Genomes and Genes
microbial colony count
Summary: Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. Each colony (i.e., microbial colony-forming unit) represents the progeny of a single cell in the original inoculum. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.
Publications266 found, 100 shown here
- Phage therapy reduces Campylobacter jejuni colonization in broilersJaap A Wagenaar
Division of Infectious Diseases, Animal Sciences Group, P O Box 65, 8200 AB Lelystad, The Netherlands
Vet Microbiol 109:275-83. 2005..This again resulted in a significant decrease in Campylobacter colonization. We conclude that phage treatment is a promising alternative for reducing C. jejuni colonization in broilers...
- New three-stage in vitro model for infant colonic fermentation with immobilized fecal microbiotaCécile Cinquin
Dairy Research Centre STELA, Pavillon Paul Comtois, Universite Laval, Quebec, QC, Canada
FEMS Microbiol Ecol 57:324-36. 2006..These results demonstrate that this new three-stage continuous culture with immobilized cells provides a useful tool for studying the infant colon ecosystem...
- Cell density and mobility protect swarming bacteria against antibioticsMitchell T Butler
University of Texas, Austin, TX 78712, USA
Proc Natl Acad Sci U S A 107:3776-81. 2010..This work has relevance to the adaptive antibiotic resistance of bacterial biofilms...
- Inhibition of Staphylococcus aureus by the commensal bacteria of human milkM P Heikkilä
Department of Applied Chemistry and Microbiology, University of Helsinki, Helsinki, Finland
J Appl Microbiol 95:471-8. 2003..To study the bacterial diversity in expressed human milk with a focus on detecting bacteria with an antimicrobial activity against Staphylococcus aureus, known as a causative agent of maternal breast infections and neonatal infections...
- Similar bifidogenic effects of prebiotic-supplemented partially hydrolyzed infant formula and breastfeeding on infant gut microbiotaMinna M Rinne
The University of Turku, 20014 Turku, Finland Department of Pediatrics, Turku University Central Hospital, 20520 Turku, Finland
FEMS Immunol Med Microbiol 43:59-65. 2005..This would suggest that early gut Bifidobacterium microbiota can be modified by special diets up to the age of 6 months...
- Bacterial competition for human nasal cavity colonization: role of Staphylococcal agr allelesGerard Lina
Centre National de Référence des Staphylocoques, INSERM E 0230, IFR 62, Faculte de Medecine Laennec, Lyon, France
Appl Environ Microbiol 69:18-23. 2003....
- A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of the rpfA gene coding for a resuscitation promoting factorLisa Rickman
Division of Mycobacterial Research, National Institute for Medical Research, Mill Hill, London NW7 1AA, UK
Mol Microbiol 56:1274-86. 2005..In summary, it has been shown that Rv3676 is a direct regulator of rpfA expression, and because rpfA codes for a resuscitation promoting factor this may implicate Rv3676 in reactivation of dormant M. tuberculosis infections...
- Susceptibility of biofilms to Bdellovibrio bacteriovorus attackDaniel Kadouri
Department of Microbiology and Immunology, Dartmouth Medical School, Hanover, NH 03755, USA
Appl Environ Microbiol 71:4044-51. 2005..In flow cell experiments B. bacteriovorus was able to decrease the biomass of both E. coli and Pseudomonas fluorescens biofilms as determined by phase-contrast and epifluorescence microscopy...
- Culture-independent methods for identifying microbial communities in cheeseJean Luc Jany
Laboratoire Universitaire de Biodiversité et Ecologie Microbienne, Université Européenne de Bretagne ESMISAB, Parvis Blaise Pascal, Technopôle de Brest Iroise, Plouzane, France
Food Microbiol 25:839-48. 2008..Further, our analysis draws attention to the lack of data available on suitable DNA sequences for identifying fungal communities in cheese and proposes some potential DNA targets...
- Airway bacterial concentrations and exacerbations of chronic obstructive pulmonary diseaseSanjay Sethi
Veterans Affairs Western New York Healthcare System 151, 3495 Bailey Avenue, Buffalo, NY 14215, USA
Am J Respir Crit Care Med 176:356-61. 2007..Bacterial concentrations are higher during exacerbation than during stable disease; however, these studies are cross sectional and devoid of strain typing...
- The capacity of nondigestible carbohydrates to stimulate fecal bifidobacteria in healthy humans: a double-blind, randomized, placebo-controlled, parallel-group, dose-response relation studyYoram Bouhnik
Department of Gastroenterology and the Therapeutic Research Unit, Hopital Lariboisiere, Paris, France
Am J Clin Nutr 80:1658-64. 2004..Nondigestible carbohydrates (NDCHs) are fermented in the colon, where they can selectively promote the growth of bifidobacteria...
- The role of parasites in sympatric and allopatric host diversificationAngus Buckling
Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK
Nature 420:496-9. 2002..These results show that exploiters can drive diversification between populations, but may inhibit diversification within populations by opposing diversifying selection that arises from resource competition...
- An improved protocol for quantification of freshwater Actinobacteria by fluorescence in situ hybridizationRaju Sekar
Max Planck Institute for Marine Microbiology, Celciusstrasse 1, D 28359 Bremen, Germany
Appl Environ Microbiol 69:2928-35. 2003..Our findings confirm that members of this lineage are among the numerically most important Bacteria of freshwater picoplankton...
- Development of a synthetic minimal medium for Listeria monocytogenesHsiang Ning Tsai
Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom
Appl Environ Microbiol 69:6943-5. 2003..Complex broth-grown L. monocytogenes had to adapt to HTM by inducing amino acid biosyntheis. HTM is the simplest minimal medium available for growth of L. monocytogenes...
- Computational improvements reveal great bacterial diversity and high metal toxicity in soilJason Gans
Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM 87501, USA
Science 309:1387-90. 2005..Metal pollution reduced diversity more than 99.9%, revealing the highly toxic effect of metal contamination, especially for rare taxa...
- Phylogenetic diversity, abundance, and axial distribution of bacteria in the intestinal tract of two soil-feeding termites (Cubitermes spp.)Dirk Schmitt-Wagner
Mikrobielle Okologie, Fachbereich Biologie, Universitat Konstanz, 78457 Konstanz, Germany
Appl Environ Microbiol 69:6007-17. 2003..Schmitt-Wagner, M. W. Friedrich, B. Wagner, and A. Brune, Appl. Environ. Microbiol. 69:6018-6024, 2003) corroborated the presence of compartment-specific bacterial communities in the gut of different Cubitermes species...
- Microbiological effects of consuming a synbiotic containing Bifidobacterium bifidum, Bifidobacterium lactis, and oligofructose in elderly persons, determined by real-time polymerase chain reaction and counting of viable bacteriaSabine Bartosch
Microbiology and Gut Biology Group, University of Dundee, Dundee, United Kingdom
Clin Infect Dis 40:28-37. 2005....
- Endogenous interleukin-18 improves the early antimicrobial host response in severe melioidosisW Joost Wiersinga
Academic Medical Center, Meibergdreef 9, Room G2 132, 1105 AZ Amsterdam, The Netherlands
Infect Immun 75:3739-46. 2007..Together, these data indicate that the enhanced production of IL-18 in melioidosis is an essential part of a protective immune response to this severe infection...
- Fecal microbiota composition and frailtySandra P van Tongeren
Department of Medical Microbiology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
Appl Environ Microbiol 71:6438-42. 2005..In contrast to this, the number of Enterobacteriaceae was significantly higher (sevenfold) in samples from very frail volunteers...
- Rapid detection of group B streptococci in pregnant women at deliveryM G Bergeron
Infectious Diseases Research Center and the Division of Microbiology, Universite Laval, Quebec, Que, Canada
N Engl J Med 343:175-9. 2000..Group B streptococcal infections are an important cause of neonatal morbidity and mortality. A rapid method for the detection of this organism in pregnant women at the time of delivery is needed to allow early treatment of neonates...
- Transfer of vancomycin resistance transposon Tn1549 from Clostridium symbiosum to Enterococcus spp. in the gut of gnotobiotic miceAline Launay
Centre d Etudes Pharmaceutiques, Chatenay Malabry, France
Antimicrob Agents Chemother 50:1054-62. 2006..These data demonstrate functionality of the Tn1549-like element and attest that the transfer of the vanB operon between enterococci and human commensal anaerobes occurs in the intestinal environment...
- Enumeration of 16S rDNA of Desulfotomaculum lineage 1 in rice field soil by real-time PCR with SybrGreen detectionStephan Stubner
Max Planck Institute for Terrestrial Microbiology, Karl von Frisch Strasse, D 35043, Marburg, Germany
J Microbiol Methods 50:155-64. 2002..Approximately half of this number was obtained in both habitats with a PCR assay specific for a Desulfotomaculum sequence cluster obtained previously from rice field soil...
- Survival of enterococci and staphylococci on hospital fabrics and plasticA N Neely
Shriners Hospitals for Children, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229 3095, USA
J Clin Microbiol 38:724-6. 2000....
- Legionella contamination in hot water of Italian hotelsPaola Borella
Department of Hygiene and Microbiology, Via Campi, 287, I 41100 Modena, Italy
Appl Environ Microbiol 71:5805-13. 2005..pneumophila serogroup 1 colonization. The possible role of chlorine in favoring the survival of Legionella species is discussed...
- The capacity of short-chain fructo-oligosaccharides to stimulate faecal bifidobacteria: a dose-response relationship study in healthy humansYoram Bouhnik
Hépato Gastroentérologie et Assistance Nutritive, Hopital Lariboisiere, 2 rue Ambroise Pare, 75475 Paris Cedex 10, France
Nutr J 5:8. 2006..5 to 10 g/d in comparison with a placebo. The aim of this presentation is to give more details about the dose-response effects of short-chain fructo-oligosaccharides (scFOS)...
- Rectal carriage of enterohemorrhagic Escherichia coli O157 in slaughtered cattleJ Christopher Low
Animal Health Group, Scottish Agricultural College, UK
Appl Environ Microbiol 71:93-7. 2005..coli O157 carriage in cattle. The data also support the hypothesis that high-level fecal shedding (> or =1 x 10(3) CFU g of feces(-1)) of enterohemorrhagic E. coli O157 results from colonization of this site...
- Stability of microbial communities in goat milk during a lactation year: molecular approachesCécile Callon
INRA Unité de Recherches Fromagères URF545, INRA, 36 rue de Salers, 15000 Aurillac, France
Syst Appl Microbiol 30:547-60. 2007..However, the composition of the community can vary according to factors other than feeding. This study opens new investigation fields in the field of raw milk microbial ecology...
- Quantification of Bifidobacterium spp., Escherichia coli and Clostridium difficile in faecal samples of breast-fed and formula-fed infants by real-time PCRJohn Penders
Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht NUTRIM, Maastricht University, 6200 MD Maastricht, The Netherlands
FEMS Microbiol Lett 243:141-7. 2005..difficile as well as E. coli are significantly lower in the gut microbiota of breast-fed infants than in that of formula-fed infants, whereas the prevalence and counts of Bifidobacterium spp. is similar among both groups...
- Hypermutability impedes cooperation in pathogenic bacteriaFreya Harrison
Department of Zoology, University of Oxford, United Kingdom
Curr Biol 15:1968-71. 2005..Cheats appeared and increased in frequency more rapidly in mutator populations. The presence of cheats was costly to the group, as shown by a negative correlation between cheat frequency and population density...
- Extracellular replication of Listeria monocytogenes in the murine gall bladderJonathan Hardy
Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
Science 303:851-3. 2004..The data suggest that L. monocytogenes may be carried in the human gall bladder...
- The rpf gene of Micrococcus luteus encodes an essential secreted growth factorGalina V Mukamolova
Institute of Biological Sciences, University of Wales, Aberystwyth, Ceredigion SY23 3DD, UK
Mol Microbiol 46:611-21. 2002....
- Assessment of the microbial diversity at the surface of Livarot cheese using culture-dependent and independent approachesJ Mounier
UMR Genie et Microbiologie des Procedes Alimentaires, INRA, AgroParisTech, Thiverval Grignon, France
Int J Food Microbiol 133:31-7. 2009..These probes allowed the detection of these yeasts directly in cheese. The use of the rRNA gene-based approach combined with FISH analysis was useful to investigate the diversity of a surface microbial consortium from cheese...
- The effectiveness of existing and modified cleaning regimens in a Welsh hospitalC J Griffith
Cardiff School of Health Sciences, University of Wales Institute Cardiff, Cardiff, UK
J Hosp Infect 66:352-9. 2007..These findings suggest that simple improvements can be made to existing cleaning regimens to increase their efficacy...
- A novel titanium wound chamber for the study of wound infections in pigsLars Steinstraesser
Department for Plastic Surgery, Burn Center, BG University Hospital Bergmannsheil, Ruhr University, Bochum, Germany
Comp Med 56:279-85. 2006..We conclude that the use of titanium chambers in pigs provides a reliable and reproducible in vivo model to investigate wound healing, wound infection, and treatment options...
- Evaluation of the bacterial vaginal flora of 20 postmenopausal women by direct (Nugent score) and molecular (polymerase chain reaction and denaturing gradient gel electrophoresis) techniquesJeremy P Burton
Canadian Research and Development Centre for Probiotics, Lawson Health Research Institute, London, Ontario, Canada
J Infect Dis 186:1770-80. 2002..This study indicates that asymptomatic BV appears to be much more common than is currently perceived; these findings may have implications for the health of postmenopausal women...
- Influence of pregnancy on the pathogenesis of listeriosis in mice inoculated intragastricallyTerri S Hamrick
College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
Infect Immun 71:5202-9. 2003....
- Persister cells and tolerance to antimicrobialsIris Keren
Department of Biology, Northeastern University, Boston, MA 02115, USA
FEMS Microbiol Lett 230:13-8. 2004..This suggests that persisters are not at a particular stage in the cell cycle, neither are they defective cells nor cells created in response to antibiotics. Our data indicate that persisters are specialized survivor cells...
- The viable but nonculturable state in bacteriaJames D Oliver
Department of Biology, University of North Carolina at Charlotte, Charlotte, NC 28223 0001, USA
J Microbiol 43:93-100. 2005..It is hoped that this mini-review will encourage researchers to consider this survival state in their studies as an alternative to the conclusion that a lack of culturability indicates the cells they are examining are dead...
- Biofilm susceptibility to bacteriophage attack: the role of phage-borne polysaccharide depolymeraseK A Hughes
British Antarctic Survey, High Cross, Cambridge, UK
Microbiology 144:3039-47. 1998..Scanning electron microscopy confirmed that specific phage could extensively degrade susceptible biofilms and continue to infect biofilm bacteria whilst EPS degradation was occurring...
- CellProfiler: free, versatile software for automated biological image analysisMichael R Lamprecht
Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
Biotechniques 42:71-5. 2007....
- Phenotypic tolerance: antibiotic enrichment of noninherited resistance in bacterial populationsC Wiuff
Department of Biology, Emory University, 1510 Clifton Rd, Atlanta, Georgia 30322, USA
Antimicrob Agents Chemother 49:1483-94. 2005....
- The characterisation of Bacillus spores occurring in the manufacturing of (low acid) canned productsS J C M Oomes
Unilever Food and Health Reseach Institute, Department of Advanced Food Microbiology, Unilever Research and Development Vlaardingen, Olivier van Noortlaan 120, 3133AT Vlaardingen, The Netherlands
Int J Food Microbiol 120:85-94. 2007..The data proofed to be useful for the generation of strain specific probes. Protocols to validate these probes in routine identification and innovation aimed at tailor made heat processing in soup manufacturing have been formulated...
- Maternal adaptive immunity influences the intestinal microflora of suckling miceRosa L Diaz
Department of Pediatrics, Division of Gastroenterology and Nutrition, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, CA, USA
J Nutr 134:2359-64. 2004....
- Bacterial dynamics in spring water of alpine karst aquifers indicates the presence of stable autochthonous microbial endokarst communitiesAndreas H Farnleitner
Institute of Chemical Engineering, Research Area Gene Technology and Applied Biochemistry, Vienna University of Technology, Getreidemarkt 166 9, A 1060 Vienna, Austria
Environ Microbiol 7:1248-59. 2005....
- Interactions in biofilms between Listeria monocytogenes and resident microorganisms from food industry premisesBrigitte Carpentier
Agence Francaise de Securite Sanitaire des Aliments, Laboratoire d Etudes et de Recherches sur la Qualité des Aliments et sur les Procédés Agro alimentaires, LERQAP, 23 avenue du Gnral De Gaulle, F 94706 Maisons Alfort, France
Int J Food Microbiol 97:111-22. 2004..monocytogenes cells adhering to the stainless steel coupons and forming microcolonies. This study suggests that the "house flora" can have a strong effect on the likelihood of finding L. monocytogenes on inert surfaces...
- PCR-based DNA amplification and presumptive detection of Escherichia coli O157:H7 with an internal fluorogenic probe and the 5' nuclease (TaqMan) assayR D Oberst
Food Animal Health and Management Center, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas 66506, USA
Appl Environ Microbiol 64:3389-96. 1998..coli O157:H7 in ground beef and potentially in other food and environmental samples...
- A toll-like receptor that prevents infection by uropathogenic bacteriaDekai Zhang
Section of Immunobiology and Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA
Science 303:1522-6. 2004..Mice lacking TLR11 are highly susceptible to infection of the kidneys by uropathogenic bacteria, indicating a potentially important role for TLR11 in preventing infection of internal organs of the urogenital system...
- Prospective, controlled, cross-over trial of alcohol-based hand gel in critical care units Mark E Rupp
Department of Internal Medicine, University of Nebraska Medical Center, Omaha, USA
Infect Control Hosp Epidemiol 29:8-15. 2008..There are limited data from prospective studies to indicate whether improvement in hand hygiene associated with the use of alcohol-based hand hygiene products results in improved patient outcomes...
- Detection and quantification of the human-specific HF183 Bacteroides 16S rRNA genetic marker with real-time PCR for assessment of human faecal pollution in freshwaterSylvie Seurinck
Laboratory of Microbial Ecology and Technology LabMET, Ghent University, Coupure Links 653, B 9000 Ghent, Belgium
Environ Microbiol 7:249-59. 2005....
- Enumeration of heterotrophs, fecal coliforms and Escherichia coli in water: comparison of 3M Petrifilm plates with standard plating proceduresH Schraft
Department of Biology, Lakehead University, Thunder Bay, ON, Canada P7B 5E1
J Microbiol Methods 60:335-42. 2005..coli. This comparison illustrates the high specificity of Petrifilm EC plates for enumeration of both fecal coliforms and E. coli in water...
- Effects of exogenous recombinant interleukin-12 on immune responses and protection against Brucella abortus in a murine modelI K Lee
Bacterial Diseases Research Unit, National Animal Disease Center, Agriculture Research Service, United States Department of Agriculture, Ames, Iowa 50010, USA
Can J Vet Res 65:223-8. 2001..05) S2308 colonization of splenic tissues. Our data suggest that although IL-12 may augment protective immunity induced by live SRB51, it does not influence protection induced by vaccination with killed SRB51...
- Presence of halophilic and alkaliphilic lactic acid bacteria in various cheesesM Ishikawa
Department of Fermentation Science, Tokyo University of Agriculture, Tokyo, Japan
Lett Appl Microbiol 44:308-13. 2007..We sought to confirm the presence of halophilic and alkaliphilic lactic acid bacteria (HALAB) of marine origin in cheeses and thus contribute to the understanding of the roles of LAB flora in cheese ripening...
- A comparison of thiosulphate-citrate-bile salts-sucrose (TCBS) agar and thiosulphate-chloride-iodide (TCI) agar for the isolation of Vibrio species from estuarine environmentsC Pfeffer
Department of Biology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA
Lett Appl Microbiol 36:150-1. 2003..The purpose of this study was to compare a recently described medium, thiosulphate-chloride-iodide (TCI), for the isolation of estuarine vibrios with thiosulphate-citrate-bile salts-sucrose (TCBS)...
- Microbiologic determinants of exacerbation in chronic obstructive pulmonary diseaseAntoni Rosell
Servei de Pneumologia, Hospital Germans Trias i Pujol, 08916 Badalona, Spain
Arch Intern Med 165:891-7. 2005....
- Programmed population control by cell-cell communication and regulated killingLingchong You
Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA
Nature 428:868-71. 2004..This circuit incorporates a mechanism for programmed death in response to changes in the environment, and allows us to probe the design principles of its more complex natural counterparts...
- Antioxidative probiotic fermented goats' milk decreases oxidative stress-mediated atherogenicity in human subjectsTiiu Kullisaar
Department of Biochemistry, Medical Faculty, University of Tartu, Tartu, Estonia
Br J Nutr 90:449-56. 2003..We conclude that the goats' milk fermented with our special antioxidative lactobacilli strain Lactobacillus fermentum ME-3 exhibits anti-atherogenic effects...
- Interleukin-18 gene-deficient mice show enhanced defense and reduced inflammation during pneumococcal meningitisPetra J G Zwijnenburg
Department of Pediatrics, Vrije Universiteit Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
J Neuroimmunol 138:31-7. 2003..These findings suggest that endogenous IL-18 contributes to a detrimental inflammatory response during pneumococcal meningitis and that elimination of IL-18 may improve the outcome of this disease...
- Double blind, placebo controlled trial of two probiotic strains in interleukin 10 knockout mice and mechanistic link with cytokine balanceJ McCarthy
Department of Medicine, University College Cork, National University of Ireland, Cork, Ireland
Gut 52:975-80. 2003..Prophylactic efficacy against colitis following lactobacillus consumption in interleukin 10 (IL-10) knockout (KO) mice has been reported. Whether this applies equally to other probiotic strains is unknown, and the mechanism is unclear...
- Prolonged impact of antibiotics on intestinal microbial ecology and susceptibility to enteric Salmonella infectionAmy Croswell
Department of Pediatrics, Division of Gastroenterology, The Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Infect Immun 77:2741-53. 2009....
- A family of autocrine growth factors in Mycobacterium tuberculosisGalina V Mukamolova
Institute of Biological Sciences, University of Wales, Aberystwyth, Ceredigion SY23 3 DD, UK
Mol Microbiol 46:623-35. 2002..The Rpf family of bacterial growth factors may therefore provide novel opportunities for preventing and controlling mycobacterial infections...
- Influence of a combination of Lactobacillus acidophilus NCFM and lactitol on healthy elderly: intestinal and immune parametersArthur C Ouwehand
Health and Nutrition, Danisco, Sokeritehtaantie 20, 02460 Kantvik, Finland
Br J Nutr 101:367-75. 2009..The results suggest that consumption of lactitol combined with L. acidophilus NCFM twice daily may improve some markers of the intestinal microbiota composition and mucosal functions...
- Discerning the complexity of community interactions using a Drosophila model of polymicrobial infectionsChristopher D Sibley
Department of Microbiology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada
PLoS Pathog 4:e1000184. 2008..aeruginosa...
- Experimental Mycobacterium tuberculosis infection of cynomolgus macaques closely resembles the various manifestations of human M. tuberculosis infectionSaverio V Capuano
Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
Infect Immun 71:5831-44. 2003..In addition, this model will provide an opportunity to study the latent M. tuberculosis infection observed in approximately 90% of all infected humans...
- Lactobacilli in the intestinal microbiota of Swedish infantsSiv Ahrne
Department of Food Technology, Engineering and Nutrition, Lund University, Box 124, 22100 Lund, Sweden
Microbes Infect 7:1256-62. 2005..Our results suggest that certain Lactobacillus species, especially L. rhamnosus, thrive in the intestinal flora of breast-fed infants. After weaning they are replaced by other Lactobacillus species of types found in food...
- Novel endophytic nitrogen-fixing clostridia from the grass Miscanthus sinensis as revealed by terminal restriction fragment length polymorphism analysisTakuya Miyamoto
Graduate School of Life Sciences, Tohoku University, Katahira, Aoba ku, Sendai, Japan
Appl Environ Microbiol 70:6580-6. 2004..When phylogenetic populations from M. sinensis and the soil around the plants were compared, group II clostridia were found to exist exclusively in M. sinensis...
- The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in miceJohn L Dahl
Tuberculosis Research Section, National Institute of Allergy and Infectious Disease, 12441 Parklawn Drive, Rockville, MD 20852, USA
Proc Natl Acad Sci U S A 100:10026-31. 2003..Thus, RelMtb is critical for the successful establishment of persistent infection in mice by altering the expression of antigenic and enzymatic factors that may contribute to successful latent infection...
- Dosage-related bifidogenic effects of galacto- and fructooligosaccharides in formula-fed term infantsG Moro
Center for Infant Nutrition, Macedonio Melloni Maternity Hospital, Milan, Italy
J Pediatr Gastroenterol Nutr 34:291-5. 2002..In this study, the bifidogenic effect of an experimental prebiotic oligosaccharide mixture consisting of low-molecular-weight galactooligosaccharides and high-molecular-weight fructooligosaccharides was analyzed in 90 term infants...
- Thermally treated grass fibers as colonizable substrate for beneficial bacterial inoculumR Trifonova
Plant Research International, Wageningen, The Netherlands
Microb Ecol 56:561-71. 2008..4%) and alpha-proteobacteria (21.7%) were prevalent in TGF. A germination assay with lettuce seeds showed that the phytotoxicity of TGF and TGE decreased due to the microbial enrichment...
- Predictive model for survival and growth of Salmonella typhimurium DT104 on chicken skin during temperature abuseT P Oscar
USDA, Agricultural Res Serv, Microbial Food Safety Research Unit and USDA 1890, Center for Food Science and Technol, Univ of Maryland Eastern Shore, Princess Anne, Maryland 21853, USA
J Food Prot 72:304-14. 2009..Thus, it was concluded that the tertiary model provided valid predictions for survival and growth of Salmonella Typhimurium DT104 from a low initial dose on both nonkosher and kosher chicken skin with native flora...
- Charge effect on the photoinactivation of Gram-negative and Gram-positive bacteria by cationic meso-substituted porphyrinsEliana Alves
Department of Biology and CESAM, University of Aveiro, 3810 193 Aveiro, Portugal
BMC Microbiol 9:70. 2009..The present study complements our previous work on the search for photosensitizers that might be considered good candidates for the photoinactivation of a large spectrum of environmental microorganisms...
- Quantification of biofilm in microtiter plates: overview of testing conditions and practical recommendations for assessment of biofilm production by staphylococciSrdjan Stepanovic
Department of Bacteriology, Institute of Microbiology and Immunology, School of Medicine, Belgrade, Serbia
APMIS 115:891-9. 2007..The obtained results should simplify quantification of biofilm formation in microtiter plates, and make it more reliable and comparable among different laboratories...
- A modified ATP benchmark for evaluating the cleaning of some hospital environmental surfacesT Lewis
University Hospitals Coventry and Warwickshire NHS Trust Hospital, Walsgrave, Coventry, UK
J Hosp Infect 69:156-63. 2008..They can also be used in the assessment of novel cleaning methods, such as steam cleaning and microfibre cloths, which have potential use in the National Health Service...
- Porphyrin derivatives as photosensitizers for the inactivation of Bacillus cereus endosporesA Oliveira
Department of Biology and CESAM, University of Aveiro, Aveiro, Portugal
J Appl Microbiol 106:1986-95. 2009....
- Control of bacterial contamination in microfiltered water dispensers (MWDs) by disinfectionFranca Zanetti
Department of Medicine and Public Health, University of Bologna, Via S Giacomo, 12 40126 Bologna, Italy
Int J Food Microbiol 128:446-52. 2009..In conclusion, hydrogen peroxide at 3% can be proposed as a suitable product for periodic disinfection of domestic MWDs, taking into consideration also its low cost and easy availability...
- Italian multicentre study on microbial environmental contamination in dental clinics: a pilot studyCesira Pasquarella
Dipartimento di Sanita Pubblica, Universita degli Studi di Parma, Italy
Sci Total Environ 408:4045-51. 2010....
- Cultivation of globally distributed soil bacteria from phylogenetic lineages previously only detected in cultivation-independent surveysMichelle Sait
Department of Microbiology and Immunology, The University of Melbourne, Victoria 3010, Australia
Environ Microbiol 4:654-66. 2002....
- Modeling microbial survival in buildup biofilm for complex medical devicesMichelle J Alfa
Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada
BMC Infect Dis 9:56. 2009..This study investigated whether the BBF matrix represents a greater challenge to disinfectant efficacy and microbial eradication than traditional biofilm (TBF), which forms when a surface is constantly bathed in fluid...
- Potential for preventing spread of fungi in air-conditioning systems constructed using copper instead of aluminiumL Weaver
Environmental Healthcare Unit, University of Southampton, Biomedical Sciences Building, Bassett Crescent East, Southampton, UK
Lett Appl Microbiol 50:18-23. 2010..As copper has been previously suggested as an antimicrobial surface, we tested the effectiveness of copper as an antifungal surface which could be used in air-conditioning systems as an alternative to aluminium...
- Quantitative real-time PCR assays to identify and quantify fecal Bifidobacterium species in infants receiving a prebiotic infant formulaMonique Haarman
Microbiology Section, Biomedical Research Department, Numico Research BV, P O Box 7005, 6700 CA Wageningen, The Netherlands
Appl Environ Microbiol 71:2318-24. 2005..38% +/- 0.98% for the OSF group). In conclusion, the specific prebiotic infant formula used induces a fecal microbiota that closely resembles the microbiota of breast-fed infants also at the level of the different Bifidobacterium species...
- Wound fluid bacterial levels exceed tissue bacterial counts in controlled porcine partial-thickness burn infectionsKarl Breuing
Division of Plastic Surgery, Brigham and Women s Hospital and Children s Hospital, Boston, Mass 02115, USA
Plast Reconstr Surg 111:781-8. 2003....
- Development and validation of a stochastic model for predicting the growth of Salmonella typhimurium DT104 from a low initial density on chicken frankfurters with native microfloraT P Oscar
U S Department of Agriculture, Agricultural Research Service, Microbial Food Safety Research Unit, Maryland 21853, USA
J Food Prot 71:1135-44. 2008..Based on this performance evaluation, the tertiary model was considered acceptable and valid for stochastic predictions of Salmonella Typhimurium DT104 growth from a low initial density on chicken frankfurters with native microflora...
- Origin and spoilage potential of the microbiota dominating genus Psychrobacter in sterile rehydrated salt-cured and dried salt-cured cod (Gadus morhua)Ingebrigt Bjørkevoll
Norwegian Institute of Fisheries and Aquaculture Research, N 9291 Tromsø, Norway
Int J Food Microbiol 84:175-87. 2003..The dominating bacterium in rehydrated salt-cured and dried salt-cured cod seems to mainly originate from the fresh fish itself and not from contamination during processing...
- Effect of brining, modified atmosphere packaging, and superchilling on the shelf life of Cod (Gadus morhua) loinsHélène L Lauzon
Matis ohf, 101 Reykjavik, Iceland
J Food Sci 74:M258-67. 2009..The shelf life of air-packed brined loins at -2 degrees C was 12 to 15 d but only 13 d under MA. The same synergistic effect did therefore not apply to brined loins as with unbrined ones...
- Impact of immunization against SpyCEP during invasive disease with two streptococcal species: Streptococcus pyogenes and Streptococcus equiClaire E Turner
Department of Infectious Diseases and Immunity, Hammersmith Hospital, Du Cane Road, London, W12 0NN, United Kingdom
Vaccine 27:4923-9. 2009..CEP-immunized mice also demonstrated reduced bacterial dissemination from S. equi intramuscular infection. Therefore immunization against SpyCEP may provide protection against other streptococci species with homologous proteases...
- Control of Pseudomonas aeruginosa and Stenotrophomonas maltophilia contamination of microfiltered water dispensers with peracetic acid and hydrogen peroxideRossella Sacchetti
Department of Medicine and Public Health, Division of Hygiene, University of Bologna, Via S Giacomo, 12 40126 Bologna, Italy
Int J Food Microbiol 132:162-6. 2009..In the case of disinfection with HP for 40 min, P. aeruginosa was not detected in most of the samples (73.7%). Numbers of S. maltophilia decreased with increasing time after treatment...
- Airway inflammation and bronchial bacterial colonization in chronic obstructive pulmonary diseaseSanjay Sethi
Division of Pulmonary Critical Care and Sleep Medicine, and Division of Infectious Diseases, Department of Medicine, University at Buffalo, Buffalo, NY, USA
Am J Respir Crit Care Med 173:991-8. 2006..This "colonization" of the tracheobronchial tree, currently believed to be innocuous, could serve as an inflammatory stimulus, independent of current tobacco smoke exposure...
- [Occurrence of bacteria from the Legionella genus in cooling water systems]Renata Matuszewska
Zakład Higieny Komunalnej, Narodowy Instytut Zdrowia Publicznego Państwowy Zakład Higieny, 00 791 Warszawa, ul Chocimska 24
Rocz Panstw Zakl Hig 59:445-54. 2008..Creation of low regulations which will put the obligation of cooling water systems monitoring of Legionella bacteria occurrence and taking preventive measures is necessary...
- Evaluation of logistic processing to reduce cross-contamination of commercial broiler carcasses with Campylobacter sppLakshmi Prasanna Potturi-Venkata
Department of Poultry Science, Auburn University, Auburn, Alabama 36849 5416, USA
J Food Prot 70:2549-54. 2007..These findings suggest that a simple logistic processing schedule can preserve the Campylobacter-negative status of broiler carcasses and result in products with enhanced food safety...
- Survival of Clostridium difficile on copper and steel: futuristic options for hospital hygieneL Weaver
Environmental Healthcare Unit, School of Biological Sciences, University of Southampton, Southampton, UK
J Hosp Infect 68:145-51. 2008..The results suggest that using copper alloys in hospitals and other healthcare facilities could offer the potential to reduce spread of C. difficile from contaminated surfaces...
- Bacterial community dynamics during the winter-spring transition in the North SeaMelanie Sapp
Alfred Wegnener Institute, Foundation for Polar and Marine Research, Biologische Anstalt Helgoland, Helgoland, Germany
FEMS Microbiol Ecol 59:622-37. 2007..Overall, results indicate that changes in the bacterial community were caused not only by abiotic factors but also by the phytoplankton community...
- Character displacement promotes cooperation in bacterial biofilmsMichael A Brockhurst
School of Biological Sciences, Biosciences Building, University of Liverpool, Crown Street, Liverpool L69 7ZB, United Kingdom
Curr Biol 16:2030-4. 2006..These results demonstrate that diversification into different ecological niches can minimize selection against cooperation in the face of local resource competition...
- Transfer coefficient models for escherichia coli O157:H7 on contacts between beef tissue and high-density polyethylene surfacesRolando A Flores
Crop Conversion Science and Engineering Research Unit, U S Department of Agriculture, Agricultural Research Service, Eastern Regional Research Center, 600 East Mermaid Lane, Wyndmoor, Pennsylvania 19038, USA
J Food Prot 69:1248-55. 2006..The parameters for the exponential model for cross-contamination with E. coli O157:H7 between beef tissue and HDPE surfaces were determined, allowing for the use of the resulting model in quantitative microbial risk assessment...
- Serotypes, virulence genes and intimin types of Shiga toxin (verocytotoxin)-producing Escherichia coli isolates from minced beef in Lugo (Spain) from 1995 through 2003Azucena Mora
Laboratorio de Referencia de E coli, Departamento de Microbioloxia e Parasitoloxia, Universidade de Santiago de Compostela USC, 27002 Lugo, Spain
BMC Microbiol 7:13. 2007..Also to establish if those STEC isolated from food possessed the same virulence profiles as STEC strains causing human infections...
- Lactobacillus salivarius CECT 5713, a potential probiotic strain isolated from infant feces and breast milk of a mother-child pairR Martin
Departamento de Nutricion, Bromatologia y Tecnologia de los Alimentos, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain
Int J Food Microbiol 112:35-43. 2006..Finally, it was strongly adhesive to Caco-2 and HT-29 cells did not produce biogenic amines and were unable to degrade gastric mucin in vitro...
- Bacteriological quality of drinking water from dispensers (coolers) and possible control measuresAndreas Baumgartner
Federal Office of Public Health, Section of Microbiology and Biotechnology, 3003 Bern, Switzerland
J Food Prot 69:3043-6. 2006..Consequently, in keeping with legal requirement for bottled spring and mineral water in Switzerland, it is also advisable that P. aeruginosa be absent in 100-ml samples of cooler water...
- Growth and lysis of the fish pathogen Moritella viscosaE Benediktsdottir
Institute of Biology, University of Iceland, Askja, Iceland
Lett Appl Microbiol 45:115-20. 2007..The sensitivity to lysis is a profound bottleneck to studies of the fish pathogen Moritella viscosa. The aim of this study was to examine the growth and the lysis process of M. viscosa cells under different physical and chemical conditions...
- Risk Factors for Methicillin-Resistant Staphylococcus aureus (MRSA) and Use of a Nasal Mupirocin Ointment in Oral Cancer InpatientsMinoru Miyake
Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan
J Oral Maxillofac Surg 65:2159-63. 2007..Elimination of methicillin-resistant Staphylococcus aureus (MRSA) is of critical importance in oral and maxillofacial surgery because control is very difficult once infection of an oral tumor or oral wound with MRSA is established...
- Biofilm-forming ability profiling of Staphylococcus aureus and Staphylococcus epidermidis mastitis isolatesM Oliveira
CIISA Faculdade de Medicina Veterinaria, Avenida da Universidade Tecnica, 1300 477 Lisboa, Portugal
Vet Microbiol 118:133-40. 2006..This method better mimics the in vivo conditions, especially in terms of the presence of calcium and iron, which in high concentrations, respectively, are known to inhibit or induce biofilm production...
- Inactivation of Pseudomonas aeruginosa and Aeromonas hydrophila by silver in tap waterNadia Silvestry-Rodriguez
Department of Agricultural and Biosystems Engineering, The University of Arizona, Tucson, Arizona, USA
J Environ Sci Health A Tox Hazard Subst Environ Eng 42:1579-84. 2007..Furthermore, silver shows promise as a secondary disinfectant, even in the presence of organic matter in concentrations that would reduce the effectiveness of free chlorine...
- Inflammation patterns induced by different Burkholderia species in miceW Joost Wiersinga
Center for Infection and Immunity Amsterdam CINIMA, Amsterdam, The Netherlands
Cell Microbiol 10:81-7. 2008..pseudomallei 1026b or AJ1D8. These data show that B. pseudomallei AJ1D8 is just as lethal as wild-type B. pseudomallei in an in vivo mouse model, and B. thailandensis is perhaps more virulent than is often recognized...
- Potential use of copper surfaces to reduce survival of epidemic meticillin-resistant Staphylococcus aureus in the healthcare environmentJ O Noyce
Environmental Healthcare Unit, University of Southampton, Southampton, UK
J Hosp Infect 63:289-97. 2006..Consequently, the contemporary application of stainless steel in hospital environments for work surfaces and door furniture is not recommended...
- Development of a HTS system:topoisomerase targets (RMI)Yuk Ching Tse Dinh; Fiscal Year: 2004..The screening system should also be applicable for targeting topoisomerases in pathogenic bacteria relevant for biodefense. ..
- Duodenal Mucosal Defense MechanismsJonathan D Kaunitz; Fiscal Year: 2013..Since Duox is hypothesized to control foregut bacterial colonization, the proposed system may bear on several important diseases, such as small intestinal bacteria overgrowth (SIBO), cystic fibrosis, and inflammatory bowel disease. ..
- The effectiveness of copper surfaces in reducing healthcare acquired infectionsDANIEL ZACHARY USLAN; Fiscal Year: 2013..This project therefore addresses the recent focus of AHRQ on novel approaches to prevention and reduction of healthcare-associated infections. ..
- ERADICATING BIOFILMS WITH AN ATMOSPHERIC GLOW PLASMAKimberly Kelly Wintenberg; Fiscal Year: 2000..The technology is relatively inexpensive and can be engineered to fit on a tabletop or to be portable. Such a device would find great use in hospitals, clinics, physican and dental offices, to name a few. ..
- An in vivo Gene Deletion System for Analyzing Temporal Requirement of the Dot/IcmZhao Qing Luo; Fiscal Year: 2009..In addition, study on this bacterium could share light on our understanding of other intracellular pathogens because L. pneumophila and these infectious agents share many pathogenic mechanisms. ..
- Novel Polymer Coatings for Prevention of Biofilms in Dental Unit WaterlinesJeffrey Dalsin; Fiscal Year: 2009..Coatings for waterlines that are designed to prevent bacterial growth would largely prevent this problem, reducing health-related risks to both patients and Dental care workers. ..
- DETECTION OF DENTAL WATER LINE BIOFILMSThomas Rogers; Fiscal Year: 2000..Development of a rapid, automated system that can be integrated into biocide control processes would be of enormous value in dealing with these multibillion dollar problems. ..
- RAPID SCREENING OF MICROBES IN URINEWAI CHUN LO; Fiscal Year: 2000..Reagent systems which will distinguish bacteria from other urine sediment elements have high potential as products. 60,000,000 annual urine microbiology cultures are performed in North America. ..
- Novel Targets for Treatment of Pseudomonas aeruginosaPhilip Lister; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- MICROBIAL ASSOCIATIONS IN PERIODONTAL HEALTH AND DISEASEAnne Haffajee; Fiscal Year: 2006..These data will provide a basis for understanding microbial community structure, ecological relationships and define desired microbiological end-point of therapy. ..
- Identification of Uncultivated and Unrecognized Pathogens of PeriodontitisANNE DENISE HAFFAJEE; Fiscal Year: 2010..The identification of such pathogens should, over time, lead to better diagnosis of disease, optimal treatment strategies for the individual patient, new therapeutic approaches and carefully targeted approaches to prevention. ..
- Three Periodontal Therapies in Current & Non-SmokersAnne Haffajee; Fiscal Year: 2007..The proposed investigation should provide a model to examine methods that could be useful in treating compromised patients whether compromised by harmful habits such as smoking, systemic disease, or genetic background. ..
- EFFECT OF ANTIBIOTICS ON ORAL BIOFILMS IN VIVOAnne Haffajee; Fiscal Year: 2001..abstract_text> ..
- C. difficile Toxin Membrane Test with Magnetic ParticlesROBERT CARMAN; Fiscal Year: 2004..perfringens enterotoxin, another cause of AAD. The technology developed in this project will be widely applicable for the development of new highly sensitive stool antigen tests. ..
- Mucin-degrading microflora for prophylactic antibioticsROBERT CARMAN; Fiscal Year: 2008..difficile, and reduces the incidence of C. difficile- induced antibiotic-associated diarrhea. [unreadable] [unreadable] [unreadable]..
- Chronic Prostatitis Collaborative Research NetworkAnthony Schaeffer; Fiscal Year: 2007..abstract_text> ..
- Novel Application of Infection Control Strategies to Limit Transmission of ESBL'SEbbing Lautenbach; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- QUINOLONE RESISTANCE IN NOSOCOMIAL URINARY INFECTIONSEbbing Lautenbach; Fiscal Year: 2004....
- Clinical Impact of Quinolone-Resistant E.coli carriageEbbing Lautenbach; Fiscal Year: 2007..unreadable] [unreadable]..
- Quinolone resistant E coli in long term care facilitiesEbbing Lautenbach; Fiscal Year: 2009..abstract_text> ..
- Novel Antimicrobial Agents Against M. tuberculosisMARCUS HORWITZ; Fiscal Year: 2008..mammalian GS, and test the toxicity of the analogs in mice. 2) Test the novel MSO analogs for their capacity to inhibit M. tuberculosis growth in broth culture, in human macrophages, and in guinea pigs. ..
- Quantitative PCR for the Detection of Fungal InfectionsDavid Fredricks; Fiscal Year: 2008..Hypothesis: Fungal 18S rDNA qPCR employing a broad range fungal probe, or a system of multiple specific probes, will be useful for detecting emerging fungal pathogens in the transplant setting. [unreadable] [unreadable]..
- Innate Effectors of rAls3p-N Anti-Candida VaccineBrad J Spellberg; Fiscal Year: 2010..PNS 398/2590 (Rev. 11/07) Page - Continuation Format Page ..
- Adrenergic Antagonism During Murine CandidiasisBrad Spellberg; Fiscal Year: 2008..For these reasons, the potential for adrenergic antagonism to act as an effective immunotherapy is highly meritorious of investigation in this training application. ..
- Effectiveness of Sealing Caries: A Way to Reduce Disparities in Dental CariesMargherita Fontana; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Cellular & Molecular Fungal Biology 2008 Gordon Research ConferenceNancy Keller; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- LcrV Plague Vaccine with Altered Immune Modulatory PropertiesOlaf Schneewind; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Attachment of Oral Actinobacillus to EpitheliumDaniel Fine; Fiscal Year: 2008..The longterm goal of this application is to use this information to identify targets for therapeutic agents that can interfere with attachment of Aa to oral tissues and thus prevent colonization leading to LAP. [unreadable] [unreadable]..
- Tularemia and the Human Innate Immune ResponseGary Klimpel; Fiscal Year: 2009..abstract_text> ..
- Human Cellular Immune Responses to LeptospiraGary Klimpel; Fiscal Year: 2009..Learning how Leptospira interact with the human immune system will lead us to understand the pathogenesis of leptospirosis and how to develop vaccines and strategies to control the associated pathology. ..
- Interdisciplinary Research:Antimicrobial Resistance(RMI)Elaine Larson; Fiscal Year: 2006..In the final year, plans for a sustainable Consortium on antimicrobial resistance will be formalized. [unreadable] [unreadable]..
- Regulation of Pulmonary Host Defense by LeptinPeter Mancuso; Fiscal Year: 2010..They will also test the use of exogenous leptin as an adjunctive therapeutic agent in the treatment of pneumococcal pneumonia. ..
- The Pore-forming Toxin of Legionella PneumophilaYousef Abu Kwaik; Fiscal Year: 2003..Our studies on L. pneumophila may provide a paradigm for other vacuolar intracellular pathogens such as Mycobacterium, Salmonella, and Chlamydia. ..
- Recombinant murine IL-10 produced in situ by H. pyloriKATHRYN EATON; Fiscal Year: 2005..pylori, but will also establish a model in which the roles of other cytokines and mediators can be determined, and host and bacterial interactions can be directly evaluated in vivo. ..
- M TUBERCULOSIS PHAGOSOMEMARCUS HORWITZ; Fiscal Year: 2002..tuberculosis to survive and multiply within its host cells and should facilitate the development of new strategies for prevention and treatment of tuberculosis. ..
- Oral Immunology/Microbiology Research Group Annual MtgDaniel Fine; Fiscal Year: 2003..Perpetuation of the OIMRG and its annual meetings greatly enhances the spirit of collegial interaction/collaboration among investigators with expertise in immunology and microbial pathogenesis as related to oral health and disease. ..
- Characterization of the Francisella tularensis phagosomeMARCUS HORWITZ; Fiscal Year: 2003..tularensis subverts the host cell membrane trafficking pathways and attains an intracellular compartment that is hospitable for its survival and growth will help guide new strategies for the prevention and treatment of tularemia. ..
- Toll-like Receptors and the Innate Immune ResponseTHOMAS HAWN; Fiscal Year: 2003..tuberculosis and L. major will reveal novel insights about innate immunity and infectious diseases that will have implications for vaccine development. ..
- BACTERIAL MODULATION OF LUNG INFLAMMATORY RESPONSEThomas Russo; Fiscal Year: 2004..g. hemolysin) and bacterially induced host response elements in directly mediating the pathogenesis of lung injury. ..
- HOME HYGIENE INTERVENTIONElaine Larson; Fiscal Year: 2002..Logistic regression, Liang-Zeger regression, and Chi Square analyses will be used to test differences in rates of transmission of symptoms and changes in quantity, types and resistance patterns of microbial flora of the hands. ..
- SORBENTS+ENGINEERED BACTERIA AS GUT-BASED UREMIA THERAPYNatarajan Ranganathan; Fiscal Year: 2002..It is equally feasible that our oral formulation may also have applications as a adjunct therapy for dialysis. ..
- Microbial Markers for Periodontal Disease in ChildrenDaniel Fine; Fiscal Year: 2005....
- Oral infection and inflammation in transplant patientsAnna Dongari Bagtzoglou; Fiscal Year: 2005....
- Periodontal Disease and PrematurityAnanda Dasanayake; Fiscal Year: 2006..The collective expertise of the investigative team and the excellent clinical and research facilities are additional strengths. ..
- Tracking Mucosal T cells to Commensal Microbes in VivoMassimo Costalonga; Fiscal Year: 2006..The data will be important to human health, establishing a framework to study in vivo mucosal infectious agents and oral vaccines. ..
- Predicting Caries Risk in Underserved ToddlersMargherita Fontana; Fiscal Year: 2005....
- PCR assays to detect individual pneumococcal serotypesLORRY RUBIN; Fiscal Year: 2006..Furthermore, they will be critical for determining the effects of current and future pneumococcal vaccines on serotype-specific carriage. ..
- Host and Bacterial Factors in Disease due to H. pyloriKathryn A Eaton; Fiscal Year: 2010..This will allow us to hire additional staff to ensure rapid completion of the remaining experiments. With these changes we fully expect to complete these experiments in 2 years. ..
- Oral Exposure and Transmission of HIVPeter Southern; Fiscal Year: 2003....
- Role of Cytokines in Two Hit Organ InjuryJean Nemzek; Fiscal Year: 2006..Successful completion of these aims could impact current two hit theories and use of immune therapy in septic patients exposed to additional inflammatory insults. ..
- P. Aeruginosa Biofilms and Burn Wound InfectionsKarin Sauer; Fiscal Year: 2006..aeruginosa pathogenesis and by identifying virulence factors that may be targeted for therapeutic intervention. ..
- The Molecular Microbiology of Bacterial VaginosisDavid Fredricks; Fiscal Year: 2003..In future studies, vaginal fluid samples from a larger cohort of women will be assayed to determine if a candidate pathogen is specifically associated with BV. ..
- A dietary supplement for augmenting kidney functionNatarajan Ranganathan; Fiscal Year: 2004..The fully developed product will have immense benefits for the uremic patients both in a higher quality of life and a decrease in the financial burden associated with renal dysfunction therapy. ..
- Incidence, risk factors, and consequences of neonatal hypothermia in NepalLUKE MULLANY; Fiscal Year: 2008..Examination of alternate cutoffs for defining hypothermia severity may improve design of low-cost technologies for identification and subsequent management of hypothermic infants in the community. [unreadable] [unreadable] [unreadable]..
- Microbiology of Stenotrophomonas maltophilia infectionJOANNA BROOKE; Fiscal Year: 2005..abstract_text> ..
- The Type III Pathway of Yersinia PestisOlaf Schneewind; Fiscal Year: 2004..Together these studies are also aimed at identifying molecular targets for drug therapies, an important area of research to aid in the defense against biological warfare and bioterrorist deployment of the select agent Y. pestis. ..
- OmpR and acid regulation of Escherichia coli fim genesWILLIAM SCHWAN; Fiscal Year: 2007..unreadable] [unreadable] [unreadable] [unreadable]..
- Oral Immunology/Microbiology Annual MeetingDaniel Fine; Fiscal Year: 2003..Perpetuation of the OIMRG and its annual meetings greatly enhances the spirit of collegial interaction/collaboration among investigators with expertise in immunology and microbial pathogenesis as related to oral health and disease. ..
- Receptor-Mediated Endocytosis of Legionella PneumophilaYousef Abu Kwaik; Fiscal Year: 2004..Our studies may uncover potential pathogenic evolution of Lpn to invade the more evolved mammalian cells, and may contribute to the understanding of invasion of protozoa by Mycobacterium and Chlamydia. ..
- Social Ordering and Mental/Physical Health in ChildrenW Boyce; Fiscal Year: 2006..abstract_text> ..
- Social Disparities in the Early Neurobiology of StressW Boyce; Fiscal Year: 2006..abstract_text> ..
- Impact of Social Stress on TLR4-Induced Microbicidal Activity of CD11b+ CellsMichael Bailey; Fiscal Year: 2008..Defining the stress-induced cellular changes that enhance immune functioning could stimulate new therapeutic approaches to treating infectious diseases. [unreadable] [unreadable] [unreadable] [unreadable]..