indirect calorimetry

Summary

Summary: Calculation of the energy expenditure in the form of heat production of the whole body or individual organs based on respiratory gas exchange.

Top Publications

  1. ncbi Inflexibility of energy substrate oxidation in type 1 diabetic patients
    Petr Wohl
    Diabetes Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Metabolism 53:655-9. 2004
  2. ncbi Day-to-day variance in measurement of resting metabolic rate using ventilated-hood and mouthpiece & nose-clip indirect calorimetry systems
    Darren M Roffey
    School of Human Movement Studies, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia
    JPEN J Parenter Enteral Nutr 30:426-32. 2006
  3. ncbi The use of uniaxial accelerometry for the assessment of physical-activity-related energy expenditure: a validation study against whole-body indirect calorimetry
    Hideaki Kumahara
    Laboratory of Physiology, Faculty of Medicine, University of Lausanne, Lausanne, Switzerland
    Br J Nutr 91:235-43. 2004
  4. ncbi Some mathematical and technical issues in the measurement and interpretation of open-circuit indirect calorimetry in small animals
    J R S Arch
    Clore Laboratory, University of Buckingham, Buckingham, UK
    Int J Obes (Lond) 30:1322-31. 2006
  5. ncbi Recommendations for improved data processing from expired gas analysis indirect calorimetry
    Robert A Robergs
    Exercise and Sports Sciences, University of Western Sydney, Sydney, New South Wales, Australia
    Sports Med 40:95-111. 2010
  6. ncbi Reduced adipose tissue triglyceride synthesis and increased muscle fatty acid oxidation in C5L2 knockout mice
    Sabina Paglialunga
    Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    J Endocrinol 194:293-304. 2007
  7. ncbi The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression
    Hironori Waki
    Howard Hughes Medical Institute, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Cell Metab 5:357-70. 2007
  8. ncbi Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanisms
    Yiying Zhang
    Department of Pediatrics, Division of Molecular Genetics, Columbia University, New York, NY 10032, USA
    Diabetes 56:1647-54. 2007
  9. ncbi Poor agreement between a portable armband and indirect calorimetry in the assessment of resting energy expenditure
    S Bertoli
    International Center for the Assessment of Nutritional Status, University of Milano, Milano, Italy
    Clin Nutr 27:307-10. 2008
  10. ncbi Whole-body fat oxidation determined by graded exercise and indirect calorimetry: a role for muscle oxidative capacity?
    P Nordby
    Copenhagen Muscle Research Centre, Department of Medical Physiology, The Panum Institute, University of Copenhagen, Copenhagen, Denmark
    Scand J Med Sci Sports 16:209-14. 2006

Detail Information

Publications265 found, 100 shown here

  1. ncbi Inflexibility of energy substrate oxidation in type 1 diabetic patients
    Petr Wohl
    Diabetes Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Metabolism 53:655-9. 2004
    ..kg(-1). min(-1) and period 2: 10 mU. kg(-1). min(-1)) combined with indirect calorimetry during basal period B (B, -45 to 0 minutes), period 1, and period 2 of the clamp...
  2. ncbi Day-to-day variance in measurement of resting metabolic rate using ventilated-hood and mouthpiece & nose-clip indirect calorimetry systems
    Darren M Roffey
    School of Human Movement Studies, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia
    JPEN J Parenter Enteral Nutr 30:426-32. 2006
    ..The 2 most common systems used to measure RMR involve a ventilated hood or a mouthpiece & nose clip to collect expired gases. The variation in measurement using these 2 approaches has not been systematically compared...
  3. ncbi The use of uniaxial accelerometry for the assessment of physical-activity-related energy expenditure: a validation study against whole-body indirect calorimetry
    Hideaki Kumahara
    Laboratory of Physiology, Faculty of Medicine, University of Lausanne, Lausanne, Switzerland
    Br J Nutr 91:235-43. 2004
    ..This method is also important for assessing the diurnal profile of physical activity...
  4. ncbi Some mathematical and technical issues in the measurement and interpretation of open-circuit indirect calorimetry in small animals
    J R S Arch
    Clore Laboratory, University of Buckingham, Buckingham, UK
    Int J Obes (Lond) 30:1322-31. 2006
    b>Indirect calorimetry is increasingly used to investigate why compounds or genetic manipulations affect body weight or composition in small animals...
  5. ncbi Recommendations for improved data processing from expired gas analysis indirect calorimetry
    Robert A Robergs
    Exercise and Sports Sciences, University of Western Sydney, Sydney, New South Wales, Australia
    Sports Med 40:95-111. 2010
    There is currently no universally recommended and accepted method of data processing within the science of indirect calorimetry for either mixing chamber or breath-by-breath systems of expired gas analysis...
  6. ncbi Reduced adipose tissue triglyceride synthesis and increased muscle fatty acid oxidation in C5L2 knockout mice
    Sabina Paglialunga
    Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    J Endocrinol 194:293-304. 2007
    ..3 +/- 2.4% versus C5L2KO: 59.5 +/- 6.8%, P < 0.001) were significantly reduced in C5L2KO mice. Indirect calorimetry measurements revealed C5L2KO mice have unchanged oxygen consumption levels yet reduced respiratory quotient ..
  7. ncbi The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression
    Hironori Waki
    Howard Hughes Medical Institute, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Cell Metab 5:357-70. 2007
    ....
  8. ncbi Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanisms
    Yiying Zhang
    Department of Pediatrics, Division of Molecular Genetics, Columbia University, New York, NY 10032, USA
    Diabetes 56:1647-54. 2007
    ..In conclusion, increases in dietary leucine intake substantially decrease diet-induced obesity, hyperglycemia, and hypercholesterolemia in mice with ad libitum consumption of HFD likely via multiple mechanisms...
  9. ncbi Poor agreement between a portable armband and indirect calorimetry in the assessment of resting energy expenditure
    S Bertoli
    International Center for the Assessment of Nutritional Status, University of Milano, Milano, Italy
    Clin Nutr 27:307-10. 2008
    To evaluate the agreement between resting energy expenditure (REE) estimated by a portable armband and measured by indirect calorimetry.
  10. ncbi Whole-body fat oxidation determined by graded exercise and indirect calorimetry: a role for muscle oxidative capacity?
    P Nordby
    Copenhagen Muscle Research Centre, Department of Medical Physiology, The Panum Institute, University of Copenhagen, Copenhagen, Denmark
    Scand J Med Sci Sports 16:209-14. 2006
    ..was calculated during prolonged and graded exercise from the respiratory exchange ratio using standard indirect calorimetry equations. Based on the graded exercise test, whole-body peak fat oxidation was determined...
  11. ncbi Indirect calorimetry: a practical guide for clinicians
    Heather A Haugen
    University of Colorado Health Sciences Center, School of Medicine, Denver, Colorado, USA
    Nutr Clin Pract 22:377-88. 2007
    This review provides clinicians with a comprehensive overview of indirect calorimetry including the principles, methodology, technologic advancements, benefits, and challenges...
  12. ncbi Evaluation of accuracy and reliability of indirect calorimetry for the measurement of resting energy expenditure in healthy dogs
    W N McDonell
    Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Canada
    Am J Vet Res 62:1761-7. 2001
    OBJECTIVE: To assess accuracy and reliability of open-flow indirect calorimetry in dogs. ANIMALS: 13 clinically normal dogs...
  13. ncbi Comparison of the standard predictive equation for calculation of resting energy expenditure with indirect calorimetry in hospitalized and healthy dogs
    Elizabeth O'Toole
    Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada
    J Am Vet Med Assoc 225:58-64. 2004
    ..To determine the level of clinical agreement between 2 methods for the measurement of resting energy expenditure (REE)...
  14. ncbi Automated VO2max calibrator for open-circuit indirect calorimetry systems
    C J Gore
    Australian Institute of Sport Adelaide, Henley Beach, Australia
    Med Sci Sports Exerc 29:1095-103. 1997
    The complete calibration of indirect calorimetry systems involves simultaneous checks of gas analyzers, volume device, and software, and this requires a machine that can mimic accurately and precisely the ventilation and expired gases of ..
  15. ncbi Indirect calorimetry: variability of consecutive baseline determinations of carbohydrate and fat utilization from gas exchange measurements
    S Gasic
    University of Vienna, Department of Medicine III, Austria
    Horm Metab Res 29:12-5. 1997
    During the past years, substantial methodological and interpretational limitations of indirect calorimetry, particularly concerning fuel utilisation, have been discussed...
  16. ncbi Predicted versus measured energy expenditure by continuous, online indirect calorimetry in ventilated, critically ill children during the early postinjury period
    Jose Luis Vazquez Martinez
    Pediatric Intensive Care Unit, Hospital Ramon y Cajal, Madrid, Spain
    Pediatr Crit Care Med 5:19-27. 2004
    Compare the energy expenditure, predicted by anthropometric equations, with that measured by continuous on-line indirect calorimetry in ventilated, critically ill children during the early postinjury period.
  17. ncbi Resting energy expenditure in severely burned children: analysis of agreement between indirect calorimetry and prediction equations using the Bland-Altman method
    Oscar E Suman
    Medical Staff Administration, Shriners Hospitals for Children, and Department of Surgery, The University of Texas Medical Branch, 815 Market Street, Galveston, TX 77550, USA
    Burns 32:335-42. 2006
    ..This study tests the hypothesis that estimates of REE vary significantly from measured REE (MREE) in a population of severely burned children, and are not accurate for determining nutritional requirements...
  18. ncbi Rate of carbon dioxide production and energy expenditure in fed and food-deprived adult dogs determined by indirect calorimetry and isotopic methods
    Etienne B Pouteau
    Department of Nutrition and Endocrinology, Ecole Nationale Veterinaire de Nantes, 44307 Nantes Cedex 3, France
    Am J Vet Res 63:111-8. 2002
    ..To evaluate energy expenditure (EE) in dogs by estimating rate of CO2 production (rCO2)...
  19. pmc The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes
    Adam B Mayerson
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8020, USA
    Diabetes 51:797-802. 2002
    ....
  20. ncbi Measurement of the components of nonexercise activity thermogenesis
    J Levine
    Endocrine Research Unit, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Physiol Endocrinol Metab 281:E670-5. 2001
    ..This novel technology has potential application for not only assessing NEAT but also tracking physical activity in free-living humans...
  21. ncbi Comparison of energy expenditure estimates from doubly labeled water, a physical activity questionnaire, and physical activity records
    Joan M Conway
    US Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet and Human Performance Laboratory, Beltsville, MD 20705, USA
    Am J Clin Nutr 75:519-25. 2002
    ..However, there is limited validation of these methods against the doubly labeled water technique for determining energy expenditure (EE)...
  22. ncbi Chamber for indirect calorimetry with accurate measurement and time discrimination of metabolic plateaus of over 20 min
    T Nguyen
    Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA
    Med Biol Eng Comput 41:572-8. 2003
    ..81 min (-1) and 0.01 min). The successful integration of the algorithm into the Pennington chambers allows for traditional 24 h energy expenditure measurements and various metabolic experiments requiring rapid responses...
  23. ncbi Achievement of steady state optimizes results when performing indirect calorimetry
    Stephen A McClave
    Department of Medicine, University of Louisville School of Medicine, Kentucky 40202, USA
    JPEN J Parenter Enteral Nutr 27:16-20. 2003
    The use of steady state as the endpoint for performance of indirect calorimetry (IC) is controversial. We designed this prospective study to evaluate the necessity and significance of achieving steady state.
  24. ncbi Estimation of daily energy needs with the FAO/WHO/UNU 1985 procedures in adults: comparison to whole-body indirect calorimetry measurements
    G Alfonzo-González
    Division of Kinesiology, Laval University, Sainte Foy, Quebec, Canada
    Eur J Clin Nutr 58:1125-31. 2004
    ..To compare estimated daily energy needs with their measured values...
  25. ncbi Measuring energy expenditure in cardiac patients using the Body Media Armband versus indirect calorimetry. A validation study
    P J Cole
    Exercise Physiology Laboratory, Bloomsburg University of Pennsylvania, Bloomsburg, PA, USA
    J Sports Med Phys Fitness 44:262-71. 2004
    The purpose of this study was to compare differences in energy expenditure using the newly developed SenseWear Armband body monitor to indirect calorimetry in cardiac rehabilitation patients.
  26. ncbi Rosiglitazone reduces liver fat and insulin requirements and improves hepatic insulin sensitivity and glycemic control in patients with type 2 diabetes requiring high insulin doses
    Leena Juurinen
    Department of Medicine, Division of Diabetes, University of Helsinki, PO Box 700, Room C418B, FIN 00029 HUCH Helsinki, Finland
    J Clin Endocrinol Metab 93:118-24. 2008
    ..Peroxisome proliferator-activated receptor (PPAR)-gamma agonists reduce liver fat. We therefore hypothesized that type 2 diabetic patients using exceptionally high doses of insulin might respond well to addition of a PPARgamma agonist...
  27. ncbi Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss
    D E Kelley
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Physiol 277:E1130-41. 1999
    ..measurement of glucose and free fatty acid (FFA) uptake (fractional extraction of [9,10 (3)H]oleate) and indirect calorimetry across the leg to determine substrate oxidation during fasting and insulin-stimulated conditions...
  28. ncbi Making indirect calorimetry a gold standard for predicting energy requirements for institutionalized patients
    Dale A Schoeller
    Department of Nutritional Sciences, University of Wisconsin Madison, Madison, WI 53706, USA
    J Am Diet Assoc 107:390-2. 2007
  29. ncbi Differential oxidation of individual dietary fatty acids in humans
    J P DeLany
    Pennington Biomedical Research Center, Baton Rouge, LA 70808 4124, USA
    Am J Clin Nutr 72:905-11. 2000
    ..Dietary fatty acids that are more prone to oxidation than to storage may be less likely to lead to obesity...
  30. ncbi Percent relative cumulative frequency analysis in indirect calorimetry: application to studies of transgenic mice
    Marc Riachi
    Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ontario K1H 8M5, Canada
    Can J Physiol Pharmacol 82:1075-83. 2004
    b>Indirect calorimetry is commonly used in research and clinical settings to assess characteristics of energy expenditure. Respiration chambers in indirect calorimetry allow measurements over long periods of time (e.g...
  31. ncbi Assessement of resting energy expenditure of obese patients: comparison of indirect calorimetry with formulae
    Valéria Girard Fabiano Alves
    Nutrition Support Service, NUTROCLIN RJ, Clínica São Vicente, Rua João Borges, 204 Gávea, Rio de Janeiro, RJ, Brazil
    Clin Nutr 28:299-304. 2009
    ..The importance of the measurement using indirect calorimetry (IC) is to avoid the administration of an inadequate caloric load, which can increase clinical morbidity...
  32. ncbi Energy balance in critical illness
    Lindsay D Plank
    Department of Surgery, University of Auckland, Auckland, New Zealand
    Proc Nutr Soc 62:545-52. 2003
    ..Nutritional therapy for these patients may in the future focus on glycaemic control with insulin and specialised supplements rather than on energy balance per se...
  33. ncbi Indirect calorimetry: methodology, instruments and clinical application
    Eduardo E Moreira da Rocha
    NUTROCLIN, Clínica São Vicente Gávea, Rio de Janeiro, Brazil
    Curr Opin Clin Nutr Metab Care 9:247-56. 2006
    This review aims to identify the basic methods for accurately measuring a patient's energy expenditure in clinical nutrition practice by indirect calorimetry, and the impact upon a disease state of applying the results obtained.
  34. ncbi Should indirect calorimetry be used as part of nutritional assessment?
    S A McClave
    University of Louisville School of Medicine, Department of Medicine, Division of Gastroenterology Hepatology, 550 South Jackson Street, Louisville, KY 40202, U S A
    J Clin Gastroenterol 33:14-9. 2001
    The use of indirect calorimetry in the design of nutritional support regimens is poorly appreciated by clinicians, who fail to recognize the importance of providing a sufficient volume of enteral feeding to critically ill patients...
  35. ncbi Which REE prediction equation should we use in normal-weight, overweight and obese women?
    M Siervo
    Department of Neuroscience and Behaviour, Dietetic and Nutrition Section, School of Medicine, University Federico II, Naples, Italy
    Clin Nutr 22:193-204. 2003
    ..We perform a critical selection of accurate and reliable prediction equations employed on normal-weight, overweight and obese young women...
  36. ncbi Validation of energy intake by dietary recall against different methods to assess energy expenditure
    M Lof
    Division of Nutrition, Department of Biomedicine and Surgery, University of Linkoping, Linkoping, Sweden
    J Hum Nutr Diet 17:471-80. 2004
    ..To provide an example showing how procedures based on recalls of physical activity can assess the validity of dietary recalls and identify subjects constantly underreporting their energy intake (EI)...
  37. ncbi Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes
    Heidi Storgaard
    Department of Endocrinology and Clinical Research Unit, Hvidovre Hospital, University of Copenhagen, DK 2650 Hvidovre, Denmark
    J Clin Endocrinol Metab 89:1301-11. 2004
    ..b>Indirect calorimetry and excision of vastus lateralis skeletal muscle biopsies were performed before and during hyperinsulinemic ..
  38. ncbi Walking for health in pregnancy: assessment by indirect calorimetry and accelerometry
    Jennifer M DiNallo
    Department of Kinesiology, The Pennsylvania State University, University Park, PA 16802 5701, USA
    Res Q Exerc Sport 79:28-35. 2008
    ..Encouraging pregnant women to walk for 30-40 min per day at a self-selected walking pace may be an appropriate public health recommendation...
  39. ncbi Body composition changes with time in pediatric burn patients
    Rene Przkora
    Department of Surgery, University of Texas Medical Branch, Texas, USA
    J Trauma 60:968-71; discussion 971. 2006
    ..Major trauma and burns are associated with whole body catabolism which can persist for 1 or more years after injury. This study investigates body composition in massively burned children for up to 2 years...
  40. pmc Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents
    Kitt F Petersen
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    PLoS Med 2:e233. 2005
    ..In order to further characterize mitochondrial activity in these individuals, we examined insulin-stimulated rates of adenosine triphosphate (ATP) synthesis and phosphate transport in skeletal muscle in a similar cohort of participants...
  41. ncbi [Study of energy expenditure in anorexia nervosa: agreement between indirect calorimatry and several equations]
    M C Cuerda Compés
    Unidad de Nutrición, Hospital General Universitario Gregorio Marañón Madrid, Espana
    Nutr Hosp 20:371-7. 2005
    ..Nutritional management is essential in anorexia nervosa (AN), although nutrient replenishment must be done progressively to prevent the occurrence of re-alimentation syndrome...
  42. ncbi Indirect calorimetry can be used to measure cardiac output in septic patients?
    Maria Auxiliadora Martins
    Division of Intensive Care Unit, Department of Surgery and Anatomy, Ribeirao Preto Faculty of Medicine, University of Sao Paulo, SP, Brazil
    Acta Cir Bras 23:118-25; discussion 125. 2008
    The aim of this study was to compare two different cardiac output (CO) monitoring systems based on the thermodilution principle (Thermo-CO) and indirect calorimetry (Fick mixed-CO) in septic patients.
  43. ncbi Effects of intracerebroventricular and intra-accumbens melanin-concentrating hormone agonism on food intake and energy expenditure
    Benjamin Guesdon
    Centre de Recherche de l Hôpital Laval et Centre de Recherche sur le Métabolisme Energétique de l Université Laval, Quebec, Canada
    Am J Physiol Regul Integr Comp Physiol 296:R469-75. 2009
    ..energy expenditure and substrate oxidation were assessed following injections in male Wistar rats using indirect calorimetry. Food intake was also measured...
  44. ncbi Non-oxidative glucose disposal is reduced in type 2 diabetes, but can be restored by aerobic exercise
    H Yokoyama
    Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Diabetes Obes Metab 10:400-7. 2008
    ..Glucose oxidation rates were assessed by indirect calorimetry, and non-oxidative GDR was calculated by subtracting glucose oxidation rate from GDR...
  45. ncbi Meals with similar energy densities but rich in protein, fat, carbohydrate, or alcohol have different effects on energy expenditure and substrate metabolism but not on appetite and energy intake
    Anne Raben
    Research Department of Human Nutrition, Center for Advanced Food Studies, The Royal Veterinary and Agricultural University, Frederiksberg, Denmark
    Am J Clin Nutr 77:91-100. 2003
    ..It has been suggested that the satiating power of the 4 macronutrients follows the oxidation hierarchy: alcohol > protein > carbohydrate > fat. However, the experimental evidence for this is still scarce...
  46. ncbi Arg64 beta3-adrenoceptor variant and the components of energy expenditure
    Jeremy Walston
    Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Obes Res 11:509-11. 2003
    ..To determine Trp64Arg beta(3)-adrenoceptor genotype-specific differences in the components of energy expenditure...
  47. ncbi Estimating human energy expenditure: a review of techniques with particular reference to doubly labelled water
    Philip Ainslie
    Department of Physiology and Biophysics, University of Calgary, Faculty of Medicine, Heritage Medical Research Building Room 209, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada
    Sports Med 33:683-98. 2003
    ..Other methods, such as direct calorimetry, indirect calorimetry systems, heart rate and EE relationships, questionnaires and activity recall, motion sensors, combined ..
  48. ncbi Measured pulmonary oxygen consumption: difference between systemic oxygen uptake measured by the reverse Fick method and indirect calorimetry in cardiac surgery
    P J Peyton
    Department of Anaesthesia, Austin Hospital, Melbourne, Australia
    Anaesthesia 60:146-50. 2005
    Measurement of oxygen uptake by indirect calorimetry was compared with the reverse Fick method in a series of patients undergoing cardiac surgery...
  49. ncbi Computerized energy balance and complications in critically ill patients: an observational study
    David Dvir
    General Intensive Care Department, Rabin Medical Center, Beilinson Campus, Petah Tiqva 49100, Israel Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Clin Nutr 25:37-44. 2006
    ..The aim of the study was to measure the daily cumulative energy balance in critically ill patients receiving mechanical ventilation using a bedside computerized information system (CIS), and to assess its impact on outcome...
  50. ncbi Reducing the time period of steady state does not affect the accuracy of energy expenditure measurements by indirect calorimetry
    Marina M Reeves
    Centre for Research in Cancer Control, Queensland Cancer Fund, Queensland 4059, Australia
    J Appl Physiol (1985) 97:130-4. 2004
    Achievement of steady state during indirect calorimetry measurements of resting energy expenditure (REE) is necessary to reduce error and ensure accuracy in the measurement...
  51. ncbi The use of indirect calorimetry in the clinical management of adolescents with nutritional disorders
    Janet Schebendach
    Department of Nutrition, CW Post Campus of Long Island University, 720 Northern Blvd, Brookville, NY 11545, USA
    Adolesc Med 14:77-85. 2003
    b>Indirect calorimetry is a noninvasive, inexpensive technique used to determine resting energy expenditure...
  52. ncbi Hyperglycemia exacerbates muscle protein catabolism in burn-injured patients
    Dennis C Gore
    Blocker Burn Unit, University of Texas Medical Branch, Galveston, USA
    Crit Care Med 30:2438-42. 2002
    ..The purpose of this study was to assess if hyperglycemia influences energy expenditure or the extent of muscle protein catabolism in severely burned adults...
  53. ncbi Indirect calorimetry in patients with active respiratory infection--prevention of cross-infection
    Achim Schwenk
    Department of Infectious Diseases, St George s Hospital Medical School, London, UK
    Clin Nutr 21:385-8. 2002
    ..This validation study tested whether the use of disposable standard-bore air tubes and an antibacterial filter, by reducing air flow, introduces an error due to recirculation of expired air in the canopy...
  54. ncbi Comparison of commonly used procedures, including the doubly-labelled water technique, in the estimation of total energy expenditure of women with special reference to the significance of body fatness
    Marie Lof
    Division of Nutrition, Department of Biomedicine and Surgery, University of Linkoping, SE 58185 Linkoping, Sweden
    Br J Nutr 90:961-8. 2003
    ..BMR and TEE were measured using indirect calorimetry (BMRmeas) and the doubly-labelled water method (TEEref) respectively...
  55. ncbi [Analysis of energy expenditure in adults with cystic fibrosis: comparison of indirect calorimetry and prediction equations]
    Casilda Olveira Fuster
    Unidad de Fibrosis Quística de Adultos, Servicio de Neumologia, Hospital Universitario Carlos Haya, Malaga, Espana
    Arch Bronconeumol 43:366-72. 2007
    ..The aim of this study was to compare resting energy expenditure determined by indirect calorimetry with that obtained with commonly used predictive equations in adults with cystic fibrosis and to assess the ..
  56. ncbi [Analysis of resting metabolic rate evaluated by indirect calorimetry in obese women with low and high caloric intake]
    Alessandra E Rodrigues
    Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
    Arq Bras Endocrinol Metabol 52:76-84. 2008
    ..the participants were divided in 3 groups: low (G1), medium (G2), high (G3) CI and were submitted to indirect calorimetry. Height, weight, body surface area (BSA), fat free mass and fat mass measured by bioimpedance were ..
  57. ncbi Resting energy expenditure in pre-dialysis diabetic patients
    C M Avesani
    Division of Nephrology, , UNIFESP, , Brazil
    Nephrol Dial Transplant 16:556-65. 2001
    ..METHODS: REE was measured by indirect calorimetry in 24 CRF diabetic patients (CRF diabetes group), matched for age, gender, and degree of renal impairment ..
  58. ncbi Harris-Benedict equation for critically ill patients: are there differences with indirect calorimetry?
    Camila C Japur
    Departamento de Clinica Medica, Universidade de Sao Paulo, Brasil
    J Crit Care 24:628.e1-5. 2009
    ..The aim of this study was to compare the measured energy expenditure (EE) and the estimated basal EE (BEE) in critically ill patients...
  59. ncbi Estimating energy expenditure from the Minnesota Leisure Time Physical Activity and Tecumseh Occupational Activity questionnaires - a doubly labeled water validation
    Joan M Conway
    USDA, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet and Human Performance Laboratory, Beltsville, MD 20705, USA
    J Clin Epidemiol 55:392-9. 2002
    ..This investigation demonstrates that a combination of previously validated physical activity questionnaires can be used to accurately determine the mean energy expenditure of a population of employed males...
  60. pmc Cumulative energy imbalance in the pediatric intensive care unit: role of targeted indirect calorimetry
    Nilesh M Mehta
    Divisions of Critical Care Medicine and Gastroenterology and Nutrition, Children s Hospital, Boston, MA, USA
    JPEN J Parenter Enteral Nutr 33:336-44. 2009
    ..Failure to accurately estimate energy requirements may result in underfeeding or overfeeding. In this study, a dedicated multidisciplinary nutrition team measured energy expenditure in critically ill children...
  61. ncbi Comparison of indirect calorimetry, the Fick method, and prediction equations in estimating the energy requirements of critically ill patients
    L Flancbaum
    Department of Human Nutrition, The Ohio State University, Columbus, USA
    Am J Clin Nutr 69:461-6. 1999
    ..Currently, the most accurate clinical tool used to measure REE is indirect calorimetry, which is expensive, requires trained personnel, and has significant error at higher inspired oxygen ..
  62. ncbi Indirect calorimetry protocol development for measuring resting metabolic rate as a component of total energy expenditure in free-living postmenopausal women
    N K Horner
    Fred Hutchinson Cancer Research Center, Cancer Prevention Research Program, Seattle, WA 98109-1024, USA
    J Nutr 131:2215-8. 2001
    ..Our purpose was to develop a practical indirect calorimetry (IC) protocol for estimating resting metabolic rate (RMR) in free-living, postmenopausal women...
  63. ncbi Comparison of resting energy expenditure in bronchopulmonary dysplasia to predicted equation
    L Bott
    Unité de Gastroentérologie, Hepatologie et nutrition, Clinique de Pediatrie, Hopital Jeanne de Flandre, Lille, France
    Eur J Clin Nutr 60:1323-9. 2006
    ..Evaluation of REE is a useful tool for nutritional management. Indirect calorimetry is an elective method for measuring REE, but it is time consuming and requires rigorous procedure...
  64. ncbi Evaluation of a portable device to measure daily energy expenditure in free-living adults
    Maxime St-Onge
    Metabolic Dysfunction Laboratory, Nutrition Department, University of Montreal, Montreal, Canada
    Am J Clin Nutr 85:742-9. 2007
    ..Increasing daily energy expenditure (EE) plays an important role in the prevention or treatment of several lifestyle-related diseases; however, its measurement remains problematic...
  65. ncbi Validity of an abbreviated indirect calorimetry protocol for measurement of resting energy expenditure in mechanically ventilated and spontaneously breathing critically ill patients
    S Petros
    Universitat Leipzig, Medizinische Klinik I, Abteilung für Intensivmedizin, Germany
    Intensive Care Med 27:1164-8. 2001
    To test a short indirect calorimetry protocol with five stable 1-min readings (5-min steady state) against the commonly used protocol of 30 1-min readings (30-min steady state) in critically ill patients with various modes of ventilation.
  66. ncbi Indirect calorimetry: a tool to adjust energy expenditure in very low birth weight infants
    Fernanda V M Soares
    Fundação Oswaldo Cruz FIOCRUZ, Rio de Janeiro, RJ, Brazil
    J Pediatr (Rio J) 83:567-0. 2007
    To determine the resting metabolic rate in very low birth weight infants through indirect calorimetry.
  67. ncbi Estimation of available energy of dietary fibres by indirect calorimetry in rats
    L Aust
    Department of Biochemistry and Physiology of Nutrition, German Institute for Human Nutrition, Arthur-Scheunert-Allee 114-116, , Germany
    Eur J Nutr 40:23-9. 2001
    ..AIM OF THE STUDY: Validation of the experimental design for short-term studies by using indirect calorimetry with feeding below maintenance requirement to evaluate the energetic availability of dietary fibres and ..
  68. ncbi Direct and indirect calorimetry of lactate oxidation: implications for whole-body energy expenditure
    Christopher B Scott
    Department of Sports Medicine, University of Southern Maine, Gorham, ME 04038, USA
    J Sports Sci 23:15-9. 2005
    ..Simultaneous direct/indirect calorimetry enabled us to determine if a thermodynamic reversal (i.e...
  69. ncbi Short-term overfeeding increases resting energy expenditure in patients with HIV lipodystrophy
    Lisa A Kosmiski
    Department of Medicine, University of Colorado at Denver, Health Sciences Center, Aurora, CO 80045, USA
    Am J Clin Nutr 86:1009-15. 2007
    ..Lipodystrophy syndromes are also associated with increased resting energy expenditure (REE). This hypermetabolism may be an adaptive response to an inability to store triacylglycerol fuel in a normal manner...
  70. ncbi Oxygen uptakes adjusted for body composition in normal-weight and obese adolescents
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Obes Res 12:513-20. 2004
    ....
  71. ncbi A low resting metabolic rate is associated with metabolic syndrome
    Silvio Buscemi
    Dipartimento di Medicina Interna, Malattie Cardiovascolari e Nefrourologiche, Facolta di Medicina, Universita di Palermo, Italy
    Clin Nutr 26:806-9. 2007
    ..The aim of this study was to investigate whether obese subjects with metabolic syndrome have a lower resting metabolic rate than obese subjects without metabolic syndrome...
  72. ncbi Conjugated linoleic acid supplementation alters the 6-mo change in fat oxidation during sleep
    Rachel N Close
    Department of Nutritional Sciences, University of Wisconsin Madison, Madison, WI, USA
    Am J Clin Nutr 86:797-804. 2007
    ..Conjugated linoleic acid (CLA) is a family of positional and geometric isomers with 2 conjugated double bonds formed from linoleic acid and linolenic acid. CLA has a wide range of biological effects, including body fat reduction...
  73. pmc Changes in energy expenditure associated with ingestion of high protein, high fat versus high protein, low fat meals among underweight, normal weight, and overweight females
    Amy Jo Riggs
    Department of Health and Kinesiology, Georgia Southern University, Statesboro, Georgia, USA
    Nutr J 6:40. 2007
    ....
  74. ncbi Effects of the interaction of sex and food intake on the relation between energy expenditure and body composition
    David R Paul
    Diet and Human Performance Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, MD 20705, USA
    Am J Clin Nutr 79:385-9. 2004
    ..It is possible that variables such as sex, food intake, or both may in part explain this poor coupling...
  75. ncbi Malnutrition is not related to alterations in energy balance in patients with stable liver cirrhosis
    O Riggio
    Department of Clinical Medicine, University of Rome La Sapienza, Italy
    Clin Nutr 22:553-9. 2003
    ..The aim of the present study was to evaluate the daily energy balance in clinically stable cirrhotic patients with or without malnutrition...
  76. ncbi No evidence of mass dependency of specific organ metabolic rate in healthy humans
    Wiebke Later
    Institute of Human Nutrition and Food Science, Christian Albrechts University, Kiel, Germany
    Am J Clin Nutr 88:1004-9. 2008
    ..However, interspecies data suggest allometric relations between body mass and organ metabolic rate with higher specific metabolic rates in mammals with a smaller body mass...
  77. ncbi Long-term persistence of adaptive thermogenesis in subjects who have maintained a reduced body weight
    Michael Rosenbaum
    Columbia University College of Physicians and Surgeons, New York Presbyterian Medical Center, New York, NY 10032, USA
    Am J Clin Nutr 88:906-12. 2008
    ..An important clinical issue is whether this reduction, which predisposes to weight regain, persists over time...
  78. ncbi Energy expenditure in African American and white boys and girls in a 2-y follow-up of the Baton Rouge Children's Study
    James P Delany
    Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Am J Clin Nutr 79:268-73. 2004
    ..Previously reported race and sex differences in energy expenditure (EE) may play a role in body fat gain...
  79. ncbi Acute effects on metabolism and appetite profile of one meal difference in the lower range of meal frequency
    Astrid J Smeets
    Department of Human Biology, Maastricht University, P O Box 616, 6200 MD, Maastricht, The Netherlands
    Br J Nutr 99:1316-21. 2008
    ..In healthy, normal-weight women, decreasing the inter-meal interval sustains satiety, particularly during the day, and sustains fat oxidation, particularly during the night...
  80. ncbi Energy expenditure, nutrition status, and body composition in children with cystic fibrosis
    Veronica B Marin
    Institute of Nutrition and Food Technology, University of Chile, Macul 5540, Santiago, Chile
    Nutrition 20:181-6. 2004
    ..Whether or not this is caused by a primary defect or energy metabolism is still a matter of controversy. To this end, we assessed energy expenditure, nutrition status, and body composition of clinically stable CF outpatients...
  81. pmc Prediction of daily energy expenditure during a feeding trial using measurements of resting energy expenditure, fat-free mass, or Harris-Benedict equations
    C Lawrence Kien
    Department of Pediatrics, University of Texas Medical Branch and the Shriners Hospital for Children, Galveston, TX, USA
    Am J Clin Nutr 80:876-80. 2004
    ..During feeding trials, it is useful to predict daily energy expenditure (DEE) to estimate energy requirements and to assess subject compliance...
  82. ncbi A weight reduction program preserves fat-free mass but not metabolic rate in obese adolescents
    Stefano Lazzer
    Protein Energy Metabolism Research Unit, Institut National de la Recherche Agronomique, University of Auvergne, Clermont Ferrand, France
    Obes Res 12:233-40. 2004
    ..To determine the effects of a multidisciplinary weight reduction program on body composition and energy expenditure (EE) in severely obese adolescents...
  83. ncbi Basal and postprandial substrate oxidation rates in obese women receiving two test meals with different protein content
    I Labayen
    Department of Physiology and Nutrition, University of Navarra, Irunlarrea, 1, 31008 Pamplona, Spain
    Clin Nutr 23:571-8. 2004
    ..The aim of this intervention study was to explore the extent to which the fat mass status and the macronutrient composition of an acute dietary intake influence substrate oxidation rates...
  84. ncbi Polymorphism in the PPARgamma2 and beta2-adrenergic genes and diet lipid effects on body composition, energy expenditure and eating behavior of obese women
    Eliane Lopes Rosado
    Departamento de Nutrição e Dietética, Instituto de Nutrição, Universidade Federal do Rio de Janeiro, Avenida Brigadeiro Trompowski s n, Cidade Universitaria, Ilha do Fundao, Rio de Janeiro RJ 21941 590, Brazil
    Appetite 49:635-43. 2007
    ..were submitted to anthropometric, biochemical, dietary, molecular, basal and postprandial metabolism (indirect calorimetry) and eating behavior (visual analog scale) evaluation...
  85. ncbi Low relative resting metabolic rate and body weight gain in adult Caucasian Italians
    S Buscemi
    Department of Internal Medicine and Cardiovascular Diseases, University of Palermo, Italy
    Int J Obes (Lond) 29:287-91. 2005
    ..To investigate the relationship between resting metabolic rate (RMR) and subsequent changes in body size and degree of fatness in a group of adult Caucasian Italians...
  86. ncbi Effect of lean system 7 on metabolic rate and body composition
    John L Zenk
    Minnesota Applied Research Center, Eden Prairie, Minnesota, USA
    Nutrition 21:179-85. 2005
    ....
  87. ncbi Interindividual variability in sleeping metabolic rate in Japanese subjects
    A A Ganpule
    Health Promotion and Exercise Program, National Institute of Health and Nutrition, 1 23 1 Toyama, Shinjuku ku, Tokyo, Japan
    Eur J Clin Nutr 61:1256-61. 2007
    ..An accurate prediction of BMR or SMR is needed to accurately predict total EE or physical activity EE for each individual. However, large variability in BMR and SMR has been reported...
  88. ncbi Carbohydrate balance predicts weight and fat gain in adults
    Robert H Eckel
    Division of Endocrinology, Metabolism, and Diabetes, University of Colorado at Denver and Health Sciences Center, PO Box 6511, MS 8106, Aurora, CO 80045, USA
    Am J Clin Nutr 83:803-8. 2006
    ..The prevention and treatment of obesity is a public health challenge...
  89. ncbi Energy balance in early-stage Huntington disease
    Ann M Gaba
    Department of Food and Nutrition Services, New York Presbyterian Hospital, New York, NY, USA
    Am J Clin Nutr 81:1335-41. 2005
    ..Huntington disease (HD) is a genetic neurologic disorder. Weight loss is common in HD and is related to progression of the disease, but the cause of weight loss remains unclear...
  90. ncbi Resting energy expenditure and body composition of Labrador Retrievers fed high fat and low fat diets
    S Yoo
    Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, 95616, USA
    J Anim Physiol Anim Nutr (Berl) 90:185-91. 2006
    ..hypothesis that high fat diets result in decreased resting energy expenditure (REE), we measured REE using indirect calorimetry in 10-adult intact male Labrador Retrievers, eating weight-maintenance high-fat (HF, 41% energy, average ..
  91. ncbi Energy requirements of non-ambulatory, tube-fed adult patients with cerebral palsy and chronic hypothermia
    Roland N Dickerson
    Department of Pharmacy, University of Tennessee, Arlington, Tennessee 38163, USA
    Nutrition 19:741-6. 2003
    ..We investigated the energy requirements of non-ambulatory patients with severe neurodevelopmental disabilities and chronic hypothermia...
  92. ncbi Ghrelin and glucagon-like peptide 1 concentrations, 24-h satiety, and energy and substrate metabolism during a high-protein diet and measured in a respiration chamber
    Manuela P G M Lejeune
    Department of Human Biology, Maastricht University, Maastricht, The Netherlands
    Am J Clin Nutr 83:89-94. 2006
    ..The mechanism of protein-induced satiety remains unclear...
  93. ncbi Prediction equation of resting energy expenditure in an adult Spanish population of obese adult population
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Ann Nutr Metab 50:193-6. 2006
    ..The aim of our study was to evaluate the accuracy of the equations to estimate REE in obese patents and develop a new equation in our obese population...
  94. ncbi Resting energy expenditure and body composition in bedridden institutionalized elderly women with advanced-stage pressure sores
    Giuseppe Sergi
    Department of Medical and Surgical Sciences, Division of Geriatrics, University of Padua, Padua, Italy
    J Gerontol A Biol Sci Med Sci 62:317-22. 2007
    ....
  95. ncbi Prediction of resting energy expenditure in a large population of obese children
    Hélène Derumeaux-Burel
    Unité du Métabolisme Protéino Energétique, National Institute for Agronomic Research University of Auvergne, Human Nutrition Research Center Auvergne, the Centre hospitalier et Universitaire, Clermont Ferrand, France
    Am J Clin Nutr 80:1544-50. 2004
    ..Recommendations for energy intake in obese children rely on accurate methods for measuring energy expenditure that cannot be assessed systematically...
  96. ncbi High-level medium-chain triglyceride feeding and energy expenditure in normal-weight women
    Elena Alexandrou
    School of Human Kinetics and Recreation, Memorial University, St John s, NL A1C 5S7, Canada
    Can J Physiol Pharmacol 85:507-13. 2007
    ..days 1 and 7 of each diet, resting metabolic rate and postprandial energy expenditure (EE) were measured by indirect calorimetry with a ventilated hood...
  97. ncbi Energy requirements of children with cerebral palsy
    S Eileen Hogan
    School of Nutrition and Dietetics, Acadia University, Wolfville, NS
    Can J Diet Pract Res 65:124-30. 2004
    ..energy recommendations for this population, resting energy expenditure should preferentially be measured by indirect calorimetry. Equations and formulae to predict healthy people's resting energy expenditure are available, but tend to ..
  98. ncbi Mechanisms of body weight gain in patients with Parkinson's disease after subthalamic stimulation
    C Montaurier
    INRA, Centre Clermont Ferrand Theix, UMR 1019, Unite de Nutrition Humaine, CRNH Auvergne, Clermont Ferrand, F 63009 France
    Brain 130:1808-18. 2007
    ..Other factors such as changes in free-living physical activity may help to limit body weight gain in some patients...
  99. ncbi Increased 24-h energy expenditure in type 2 diabetes
    Christian Bitz
    Department of Human Nutrition, The Royal Veterinary and Agricultural University, Rolighedsvej 30, 1958 Frederiksberg C, Denmark
    Diabetes Care 27:2416-21. 2004
    ....
  100. ncbi Body composition, muscle function, and energy expenditure in patients with liver cirrhosis: a comprehensive study
    Szelin Peng
    Department of Surgery, University of Auckland, Auckland, New Zealand
    Am J Clin Nutr 85:1257-66. 2007
    ..Data describing the nutritional status of patients with liver cirrhosis of diverse origin, as assessed by direct body-composition methods, are limited...
  101. ncbi Gene or size: metabolic rate and body temperature in obese growth hormone-deficient dwarf mice
    Carola W E Meyer
    Animal Physiology, Department of Biology, Karl von Frisch Strasse 8, Philipps University Marburg, D 35043 Marburg, Germany
    Obes Res 12:1509-18. 2004
    ..In this study, the basic thermal and metabolic properties of SMA1 mice were examined to detect metabolic alterations that can support the accretion of excess fat...

Research Grants64

  1. Mechanisms of action of ghrelin in muscle and adipose tissue in cancer-related ca
    Jose M Garcia; Fiscal Year: 2013
    ..Energy expenditure measurements will be performed by indirect calorimetry. Based on the data generated in our current model, we also will test the hypothesis that the same ..
  2. Role of GDNF in the regulation of hepatic steatosis
    SHANTHI K SRINIVASAN; Fiscal Year: 2013
    ..in human and murine hepatocytes (iii) GDNF-tg mice demonstrate enhanced energy utilization assessed by indirect calorimetry, (iv) compared to WT mice fed a high fat diet the GDNF-tg mice have lower serum glucose levels and improved ..
  3. Phospholipid-Mediated Metabolic Control in Liver and Brown Adipose Tissue
    David E Cohen; Fiscal Year: 2013
    ..Aim 2 will utilize indirect calorimetry, as well as cultured primary brown adipocytes in order to assess whether PC-TP-Them2 interactions limit ..
  4. Novel Small Molecule Therapeutics to Treat Obesity
    SUSAN MEDGHALCHI; Fiscal Year: 2010
    ..chronic treatment of DIO mice without toxicity, (d) increase fatty acid oxidation in DIO mice as measure by indirect calorimetry, (e) eliminate steatosis, normalize blood glucose, and reduce serum triglyceride levels in DIO mice, (f) ..
  5. Mechanisms for the Effects of Hypothalamic PTP1B on Energy Balance
    KARYN JOANNE CATALANO; Fiscal Year: 2010
    ..deletion on body weight, body composition using dual energy x-ray absorptiometry, energy expenditure using indirect calorimetry, and glucose metabolism (Aim #1)...
  6. Nutrition and Physical Activity Assessment Study (NPAAS)
    Ross L Prentice; Fiscal Year: 2013
    ..will be measured using a doubly-labeled water protocol, as will resting energy expenditure (REE) using indirect calorimetry with 0.9TEE-REE as objective measure of AREE...
  7. AREA: Rapamycin, ambient temperature, and longevity
    Steven J Swoap; Fiscal Year: 2010
    ..We propose to use indirect calorimetry and a telemetry-based heart rate and body temperature detection system to measure these physiological ..
  8. Preoptic histamine signaling in thermoregulation and energy expenditure
    IUSTIN VIRGIL TABAREAN; Fiscal Year: 2012
    ..body temperature and energy expenditure will be investigated in Specific Aim3 which will use telemetry, indirect calorimetry and ex-vivo quantification of the expression of uncoupling proteins 1, 2 and 3 at the mRNA and protein ..
  9. Maternal Overweight: Consequences for Insulin Signaling in the Offspring
    Kartik Shankar; Fiscal Year: 2013
    ..In Specific Aim 1, indirect calorimetry will be utilized to examine if gestational OW decreases energy expenditure in the offspring...
  10. Effects of chronic sleep restriction on energy homeostasis in healthy adults
    ANDREA MARIE SPAETH; Fiscal Year: 2013
    ..Aim 1) and energy expenditure (resting metabolic rate and diet-induced thermogenesis measured using indirect calorimetry;Specific Aim 2) and will explore whether the effects of sleep restriction on weight gain and ..
  11. Neuroendocrine Regulation of Adipocyte Metabolism
    Diego Perez-Tilve; Fiscal Year: 2013
    ..To further dissect that phenomenon we combine neuropharmacology and genetic deletion studies with automated indirect calorimetry, insulin-glucose clamps, pair feeding models, and molecular biochemistry of lipid metabolism...
  12. REGULATION OF HEPATIC AND PERIPHERAL GLUCOSE METABOLISM
    Ralph A DeFronzo; Fiscal Year: 2013
    ..Using the euglycemic insulin clamp with indirect calorimetry and vastus lateralis muscle biopsies, we will examine the effect of sustained hyperglycemia (+25 mg/dl) on ..
  13. CHILDHOOD METABOLIC MARKERS OF ADULT MORBIDITY IN BLACKS
    Silva Arslanian; Fiscal Year: 2009
    ..infusion to elevate circulating FFA levels;the hyperinsulinemiceuglycemic clamp with stable isotopes and indirect calorimetry to measure insulin sensitivity and substrate turnover;the hyperglycemic clamp to assess insulin secretion;..
  14. Carnitine Acetyltransferase in Defending Mitochondrial and Metabolic Function
    Deborah M Muoio; Fiscal Year: 2013
    ..Primary outcome measures will include indirect calorimetry, multiple measures of insulin action and metabolic flux, along with state-of-the-art mass spectrometry-..
  15. Exploring Specific Metabolic Rates of Major Cell Categories in Adiposity-Diverse
    ZiMian Wang; Fiscal Year: 2010
    ..The REE is measured by indirect calorimetry, and the Ci is quantified from organ/tissue mass by magnetic resonance imaging (MRI), with cellularity ..
  16. Metabolic Syndrome--Prepubertal African Amer./Caucasian
    Melinda Sothern; Fiscal Year: 2009
    ..and liver by Nuclear Magnetic Resonance pectroscopy (ill-MRS) and energy metabolism by ventilated hood indirect calorimetry. A secondary aim is to examine he relationship of birth weight and ethnicity (African American vs...
  17. Heart and Skeletal Muscle Metabolism, Energetics and Function in Barth Syndrome
    William Todd Cade; Fiscal Year: 2013
    ..production using magnetic resonance spectroscopy, skeletal muscle function by graded exercise testing and indirect calorimetry, heart function by echocardiography, and myocyte nutrient pathway mechanism examination by pluripotent stem ..
  18. Integrated system for phenotyping energy balance and metabolism in animal models
    Daniel Pomp; Fiscal Year: 2010
    ..This includes measurement of indirect calorimetry (O2 consumption &CO2 production, respiratory exchange rate, energy expenditure), feeding and drinking ..
  19. Cincinnati Mouse Metabolic Phenotyping Center
    Patrick Tso; Fiscal Year: 2013
    ..simple and detailed parameters of energy intake (food intake) and energy expenditure (including use of indirect calorimetry) and determine body composition and fat content...
  20. TSE LabMaster - CaloS-Dri/Fed+AC/Act.XY-Tel, 3x8 Mice
    Matthias H Tschop; Fiscal Year: 2010
    ..Key features are state-of-the-art open-circuit indirect calorimetry with high-speed gas sensors, and simultaneous and continuous monitoring of food and water consumption, ..
  21. Advancing the Understanding of Drug-Induced Allostasis
    Douglas S Ramsay; Fiscal Year: 2013
    ..Our laboratory uses a sophisticated experimental model that combines direct and indirect calorimetry so that core temperature and its determinants (metabolic heat production and heat release) can be ..
  22. Energy Expenditure in Subjects Successful at Weight Loss Maintenance
    Victoria A Catenacci; Fiscal Year: 2011
    ..We will use doubly labeled water to measure TDEE and total daily activity thermogenesis (TDAT), indirect calorimetry to measure RMR and thermic effect of food, and state of the art physical activity monitoring systems to ..
  23. Measuring free-living energy expenditure using direct calorimetry
    Edward L Melanson; Fiscal Year: 2013
    ..accuracy;b) compare the accuracy of this approach against the criterion measurements of DLW and whole-room indirect calorimetry;and c) compare the accuracy against a similar instrument that measures heat flux, but is not capable of ..
  24. Comprehensive Lab Animal Monitor System (CLAMS) for Rodent Metabolism and Behavio
    Gabriele V Ronnett; Fiscal Year: 2010
    ..Lab Animal Monitor System (CLAMS) to permit the continuous and simultaneous monitoring and assessment of indirect calorimetry (VO2, RER), food intake, physical activity, and voluntary and stimulus-driven exercise...
  25. Drug-Induced Allostasis and Its Motivational Effects During Adolescence
    Douglas S Ramsay; Fiscal Year: 2012
    ..The proposed studies use a sophisticated experimental model that combines direct and indirect calorimetry so that core temperature and its determinants (metabolic heat production and heat release) can be ..
  26. Study of Latinos: Nutrition &Physical Activity Assessment Study (SOLNAS)
    Yasmin Mossavar-Rahmani; Fiscal Year: 2013
    ..data from study questionnaires to the Actical (an accelerometer for measuring physical activity), DLW and indirect calorimetry. 2) To contrast measurement error properties of: (i) the 24 hr dietary recall;(ii) the 24 hr dietary recall ..
  27. ENERGY EXPENDITURE RESPONSES TO ACUTE AND CHRONIC EXERCISE IN OLDER WOMEN
    Xuewen Wang; Fiscal Year: 2013
    ..EE (using doubly labeled water) and its components (resting metabolic rate, thermic effect of feeding via indirect calorimetry, and non-exercise activity EE using the Physical Activity Monitoring System) at baseline and post-..
  28. Heart Rate and Movement Integration to Improve Physical Activity Assessment
    Scott J Strath; Fiscal Year: 2013
    ..sensor approach, and developing individualized heart rate and accelerometer calibrations relative to indirect calorimetry. Based upon these results the laboratory data will be modeled to explore conditional integrative models to ..
  29. DIETARY OMEGA-3 FATTY ACIDS, GENE EXPRESSION AND GROWTH
    William Heird; Fiscal Year: 2001
    ..Energy expenditure will be determined at the same time by indirect calorimetry and correlated with mRNA abundances...
  30. ALTERATIONS IN BODY COMPOSITION AND GROWTH AT PUBERTY
    Alan Rogol; Fiscal Year: 1999
    ..intake (nonconsecutive, 7 day, 24 hr diet recall), energy expenditure (EE; via doubly labeled water, indirect calorimetry, 7 day physical activity recall) and physical fitness (via V02 peak), which act on the genetic background...
  31. ENERGY EXPENDITURE RESPONSES TO ACUTE AND CHRONIC EXERCISE IN OLDER WOMEN
    Xuewen Wang; Fiscal Year: 2010
    ..EE (using doubly-labeled water) and its components (resting metabolic rate, thermic effect of feeding via indirect calorimetry, and non-exercise activity thermogenesis using the Physical Activity Monitoring System), and laboratory ..
  32. The Role of Ghrelin in Cancer Cachexia
    Jose M Garcia; Fiscal Year: 2013
    ..Resting energy expenditure will be measured by indirect calorimetry. Functional performance will be assessed by questionnaires and by measuring changes in muscle strength, ..
  33. MEGESTROL ACETATE FOR TREATMENT OF CANCER CACHEXIA
    David Heber; Fiscal Year: 1992
    ..We plan to measure food intake using dietary records, and energy expenditure both at rest by indirect calorimetry under controlled metabolic ward conditions and in ambulatory patients using the doubly labelled water ..
  34. CADENCE-KIDS: Cadence and Intensity in Children and Adolescents
    Catrine E Tudor-Locke; Fiscal Year: 2013
    ..Under laboratory conditions we will calibrate different treadmill cadences with indirect calorimetry. We will subsequently monitor these same individuals'habitual minute-by-minute cadence for one week...
  35. Protein and Energy Use in Pediatric Crohn's Disease
    Steven J Steiner; Fiscal Year: 2010
    ..Resting energy expenditure, using indirect calorimetry, and total energy expenditure, using doubly-labeled water, will be calculated at each visit...
  36. GLUCONEOGENESIS & DE NOVO LIPOGENESIS IN CYSTIC FIBROSIS
    DANA HARDIN; Fiscal Year: 2000
    ..Cystic fibrosis is a catabolic condition, yet the etiology of catabolism is poorly understood. Using indirect calorimetry, we recently reported that CF patients have de novo lipogenesis...
  37. Technology to Improve Assessment of Physical Activity
    John Jakicic; Fiscal Year: 2005
    ..1 we will compare energy expenditure from the KAL-X Sensor to a criterion measure of energy expenditure (indirect calorimetry)...
  38. CHILD MOBILITY: ROLE OF STRENGTH, BODY FAT & ENERGY COST
    CRAIG MC DONALD; Fiscal Year: 2000
    ..3) quantitative isometric and isokinetic strength at the elbow and knee, 4) resting metabolic rate (RMR) by indirect calorimetry, 5) energy cost of ambulation and/or wheelchair locomotion (ml O2/Kg meter and Kcal/Kg meter) via a ..
  39. EXERCISE AND ENERGY/SUBSTRATE UTIL IN BLACKS WITH NIDDM
    Dara Schuster; Fiscal Year: 2002
    ..laboratory data, assessment of glucose turnover rates with D-3 3H glucose infusion and concomitant IGTT and indirect calorimetry. On study day 2, each subject will have a dual energy x-ray absorptiometry (DEXA) scan and a magnetic ..
  40. Does CR Alter the Metabolic Rate of Specific Tissues
    Roger McCarter; Fiscal Year: 2004
    ..Using PET measurements together with magnetic resonance imaging and indirect calorimetry, we propose to provide the first test of the Hypothesis: The extended longevity of caloric restriction and ..
  41. FUEL METABOLISM DURING AND AFTER EXERCISE IN DIABETES
    John Devlin; Fiscal Year: 1991
    ..Whole body rates of carbohydrate and lipid oxidation and total energy expenditure will be estimated by indirect calorimetry. Total glucose disposal and endogenous glucose production in the basal state and during insulin infusions ..
  42. DIFFERENTIAL METABOLISM OF DIETARY FATTY ACIDS
    CRAIG KIEN; Fiscal Year: 2003
    ..This would have significance to the treatment and prevention of obesity. Indirect calorimetry will be performed in the fed and fasting state in 34 young, healthy adults who will be studied under two ..
  43. LabMaster: Calo/Dri-Fed/Act.XYZ/Wheel 16 Mice/Rats
    Michael Schwartz; Fiscal Year: 2009
    ..b>Indirect calorimetry is used to monitor rates of oxygen consumption and carbon dioxide production by monitoring gas ..
  44. Objective Physical Activity and Cardiovascular Health in Women Aged 80 and Older
    Andrea Z LaCroix; Fiscal Year: 2013
    ..200 women for participation in a clinic visit to measure energy expenditure during various activities using indirect calorimetry. This evidence is crucial for formulating evidence-based physical activity guidelines that pertain to the ..
  45. GENERAL CLINICAL RESEARCH CENTER
    John Daly; Fiscal Year: 2002
    ..perform state-of-the-art biochemical analyses and versed in the use of sophisticated methodology including indirect calorimetry, glucose, fat and protein turnover studies using stable isotopes and gas chromatography-mass spectrometry, ..
  46. INSULIN RESISTANCE AND GLUCOSE METABOLISM IN PREGNANCY
    Patrick Catalano; Fiscal Year: 1991
    ..weighing; (4) islet cell antibodies; and, (5) the hyperinsulinemic-euglycemic clamp with simultaneous indirect calorimetry. The specific methodology employed will allow evaluation of: (1) endogenous glucose production in the basal ..
  47. Nitrous Oxide, Individual Differences, and Conditioning
    Douglas Ramsay; Fiscal Year: 2007
    ..By combining direct and indirect calorimetry with implanted telemetric temperature assessment, core temperature and its determinants (metabolic heat ..
  48. ENDOSCOPIC LASER THERAPY FOR ESOPHAGEAL CANCER
    Benjamin Krevsky; Fiscal Year: 1993
    ..transit scintigraphy, endoscopic ultrasound, nutritional assessment, calorie and nutrient intake diary, indirect calorimetry, and Karnofsky performance assessment. Patients determined to be curable by surgery will be excluded...
  49. PATHWAYS OF SKELETAL MUSCLE GLUCOSE METABOLISM IN MAN
    Lawrence Mandarino; Fiscal Year: 1991
    ..will be used to measure muscle glucose uptake, release of glycolytic products, glucose oxidation (muscle indirect calorimetry) and storage as glycogen during infusions of insulin and glucose nd manipulations of plasma FFA levels...
  50. New Accelerometry Method for Energy Expenditure and Fitness Assessment Devices
    John Richardson; Fiscal Year: 2007
    ..Phase I, subjects will be instrumented with our device and a common activity monitor and gas-exchange indirect calorimetry will be the criterion for EE...
  51. PHARMACOGENETICS OF PRO12ALA PPAR GAMMA 2 IN DIABETES
    ALAN SHULDINER; Fiscal Year: 2002
    ..euglycemic hyperinsulinemic clamp), and fat metabolism (lipolysis by microdialysis and fat oxidation by indirect calorimetry. Furthermore, to detect novel genes and pathways that predict rosiglitazone responsivity and/or influence ..
  52. AGE, EXERCISE, DIET--EFFECTS ON GLUCOSE/FATTY ACID CYCLE
    John Kirwan; Fiscal Year: 1999
    ..b>Indirect calorimetry will be used to examine changes in carbohydrate and fat oxidation...
  53. Dietary Protein Requirements in Hemodialysis Patients
    Joel Kopple; Fiscal Year: 2007
    ..60, 0.80, 1.00, 1.15 and 1.30 g/kg/day. Energy intake for each patient will be based on their indirect calorimetry. The key outcome measure is nitrogen balance...
  54. Exercise Substrate Utilization:The Crossover Concept
    George Brooks; Fiscal Year: 2006
    ..use the combination of tracers {[1-13C]palmitate, [1,1,2,3,3-2H2]-glycerol (D5-glycerol), and D2-glucose}, indirect calorimetry, (a-v) measurements, biopsies, and, possibly, NMR spectroscopy...
  55. Increased Gluconeogenesis Is One Cause of CFRD
    DANA HARDIN; Fiscal Year: 2006
    ..We will measure resting energy expenditure using indirect calorimetry and intake of carbohydrate, protein and fat will be quantified with a three day food journal...
  56. Can IGF-I/IGFBP-3 Reverse Central Fat Accumulation?
    Morris Schambelan; Fiscal Year: 2005
    ..proton spectroscopy), insulin-mediated glucose uptake and disposal (euglycemic hyperinsulinemic clamp with indirect calorimetry), oral glucose tolerance, integrated lipid and carbohydrate metabolism (stable isotope studies of glucose ..
  57. REGULATION OF ENERGY BALANCE--INTESTINAL MECHANISMS
    Richard Atkinson; Fiscal Year: 1999
    ..The specific aims for the in vivo studies are to use indirect calorimetry to assess energy expenditure (EE) in VIT and control rats with perturbations that stimulate the SNS, ..
  58. Exercise and energy/substrate use in blacks with NIDDM
    Dara Schuster; Fiscal Year: 2002
    ..laboratory data, assessment of glucose turnover rates with D-3 3H glucose infusion and concomitant OGTT and indirect calorimetry. On study day 2, each subject will have a dual energy x-ray absorptiometry (DEXA) scan and a magnetic ..
  59. INSULIN ACTION IN CYSTIC FIBROSIS
    DANA HARDIN; Fiscal Year: 1999
    ..Insulin action on protein; turnover will be determined using the stable isotope [1-13C]leucine. Indirect calorimetry at baseline and maximal glucose uptake during the clamp will allow determination of glucose oxidation, non-..
  60. ENERGY EXPENDITURE AND THE INCIDENCE OF OBESITY
    William Dietz; Fiscal Year: 1993
    ..and the energy cost of activity (TDEE/BMR) will be measured during the first two years of the study suing indirect calorimetry and the doubly labeled water method (2h2018)...
  61. FAMILY SYSTEMS APPROACH TO CHILDHOOD OBESITY
    Susan Johnson; Fiscal Year: 2000
    ..3) their body composition characteristics; 4) 24 hour energy expenditure as determined by whole room indirect calorimetry; and 5) selected psychological variables such as children's self-esteem, body image and their perception of ..
  62. DIABETES IN HEMOCHROMATOSIS: PREVALENCE AND MECHANISMS
    Donald McClain; Fiscal Year: 2007
    ..if humans with HH exhibit a preference for fat oxidation over glucose oxidation by characterizing them by indirect calorimetry, FSIVGTT, serum adiponectin and measurment of the metabolic fate of [1,2-13C]glucose...
  63. COMPARATIVE STUDIES OF INTRACELLULAR GLUCOSE METABOLISM
    Robert Henry; Fiscal Year: 1992
    ..will be employed to measure glucose uptake rates in conjunction with simultaneous computerized open circuit indirect calorimetry to quantitate oxidative and non-oxidative glucose metabolism (NOGM)...
  64. ENERGETIC ADAPTATION TO THE MENOPAUSE TRANSITION
    Dwight Matthews; Fiscal Year: 2001
    ..We will use: 1) doubly labeled water and indirect calorimetry to measure changes in total daily energy expenditure, resting metabolic rate, thermic effect of a meal and ..