calibration

Summary

Summary: Determination, by measurement or comparison with a standard, of the correct value of each scale reading on a meter or other measuring instrument; or determination of the settings of a control device that correspond to particular values of voltage, current, frequency or other output.

Top Publications

  1. ncbi A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
    B M Bolstad
    Group in Biostatistics, University of California, Berkeley, CA 94720, USA
    Bioinformatics 19:185-93. 2003
  2. ncbi Calibration of the Computer Science and Applications, Inc. accelerometer
    P S Freedson
    University of Massachusetts, Department of Exercise Science, Amherst 01003, USA
    Med Sci Sports Exerc 30:777-81. 1998
  3. ncbi Calibration of two objective measures of physical activity for children
    Kelly R Evenson
    Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill 27514 USA
    J Sports Sci 26:1557-65. 2008
  4. ncbi Calibration of accelerometer output for children
    Patty Freedson
    Department of Exercise Science, University of Massachusetts, Amherst, MA 01003, USA
    Med Sci Sports Exerc 37:S523-30. 2005
  5. ncbi Testing the impact of calibration on molecular divergence times using a fossil-rich group: the case of Nothofagus (Fagales)
    Hervé Sauquet
    Laboratoire Ecologie, Systématique, Evolution, Universite Paris Sud, CNRS UMR 8079, 91405 Orsay, France
    Syst Biol 61:289-313. 2012
  6. ncbi Variance stabilization applied to microarray data calibration and to the quantification of differential expression
    Wolfgang Huber
    Department of Molecular Genome Analysis, German Cancer Research Center, INF 280, Heidelberg, 69120, Germany
    Bioinformatics 18:S96-104. 2002
  7. ncbi Validation and calibration of an accelerometer in preschool children
    Russell R Pate
    Arnold School of Public Health, University of South Carolina, 730 Devine Street, Columbia, SC 29208, USA
    Obesity (Silver Spring) 14:2000-6. 2006
  8. ncbi Hierarchy of individual calibration levels for heart rate and accelerometry to measure physical activity
    Søren Brage
    MRC Epidemiology Unit, Cambridge CB1 9NL, UK
    J Appl Physiol (1985) 103:682-92. 2007
  9. pmc Genetic calibration of species diversity among North America's freshwater fishes
    Julien April
    Institut de Biologie Intégrative et des Systèmes, Universite Laval, Quebec, QC, Canada G1V 0A6
    Proc Natl Acad Sci U S A 108:10602-7. 2011
  10. ncbi Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data
    Christian Ramakers
    Department of Anatomy and Embryology K2 283, Experimental and Molecular Cardiology Group, Academic Medical Centre, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands
    Neurosci Lett 339:62-6. 2003

Detail Information

Publications374 found, 100 shown here

  1. ncbi A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
    B M Bolstad
    Group in Biostatistics, University of California, Berkeley, CA 94720, USA
    Bioinformatics 19:185-93. 2003
    ..Normalization is a process for reducing this variation. It is common to see non-linear relations between arrays and the standard normalization provided by Affymetrix does not perform well in these situations...
  2. ncbi Calibration of the Computer Science and Applications, Inc. accelerometer
    P S Freedson
    University of Massachusetts, Department of Exercise Science, Amherst 01003, USA
    Med Sci Sports Exerc 30:777-81. 1998
    ..We established accelerometer count ranges for the Computer Science and Applications, Inc. (CSA) activity monitor corresponding to commonly employed MET categories...
  3. ncbi Calibration of two objective measures of physical activity for children
    Kelly R Evenson
    Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill 27514 USA
    J Sports Sci 26:1557-65. 2008
    A calibration study was conducted to determine the threshold counts for two commonly used accelerometers, the ActiGraph and the Actical, to classify activities by intensity in children 5 to 8 years of age...
  4. ncbi Calibration of accelerometer output for children
    Patty Freedson
    Department of Exercise Science, University of Massachusetts, Amherst, MA 01003, USA
    Med Sci Sports Exerc 37:S523-30. 2005
    ..This paper reviews the calibration of four different accelerometers used most frequently to assess physical activity and sedentary behavior in ..
  5. ncbi Testing the impact of calibration on molecular divergence times using a fossil-rich group: the case of Nothofagus (Fagales)
    Hervé Sauquet
    Laboratoire Ecologie, Systématique, Evolution, Universite Paris Sud, CNRS UMR 8079, 91405 Orsay, France
    Syst Biol 61:289-313. 2012
    Although temporal calibration is widely recognized as critical for obtaining accurate divergence-time estimates using molecular dating methods, few studies have evaluated the variation resulting from different calibration strategies...
  6. ncbi Variance stabilization applied to microarray data calibration and to the quantification of differential expression
    Wolfgang Huber
    Department of Molecular Genome Analysis, German Cancer Research Center, INF 280, Heidelberg, 69120, Germany
    Bioinformatics 18:S96-104. 2002
    We introduce a statistical model for microarray gene expression data that comprises data calibration, the quantification of differential expression, and the quantification of measurement error...
  7. ncbi Validation and calibration of an accelerometer in preschool children
    Russell R Pate
    Arnold School of Public Health, University of South Carolina, 730 Devine Street, Columbia, SC 29208, USA
    Obesity (Silver Spring) 14:2000-6. 2006
    ..Studies of physical activity in young children are limited by the lack of valid and acceptable measures. The purpose of this study was to calibrate and validate the ActiGraph accelerometer for use with 3- to 5-year-old children...
  8. ncbi Hierarchy of individual calibration levels for heart rate and accelerometry to measure physical activity
    Søren Brage
    MRC Epidemiology Unit, Cambridge CB1 9NL, UK
    J Appl Physiol (1985) 103:682-92. 2007
    ..between physical activity intensity (PAI) and HR and accelerometry, which may be reduced by individual calibration. However, individual calibration limits feasibility of these techniques in population studies, and less ..
  9. pmc Genetic calibration of species diversity among North America's freshwater fishes
    Julien April
    Institut de Biologie Intégrative et des Systèmes, Universite Laval, Quebec, QC, Canada G1V 0A6
    Proc Natl Acad Sci U S A 108:10602-7. 2011
    ..Indeed, nearly 10% of species diversity is thought to remain undescribed. To provide an independent calibration of taxonomic uncertainty and to establish a more accessible molecular identification key for its application, ..
  10. ncbi Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data
    Christian Ramakers
    Department of Anatomy and Embryology K2 283, Experimental and Molecular Cardiology Group, Academic Medical Centre, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands
    Neurosci Lett 339:62-6. 2003
    ..A computer program to perform this calculation is available on request (e-mail: bioinfo@amc.uva.nl; subject: LinRegPCR)...
  11. ncbi Collision cross sections of proteins and their complexes: a calibration framework and database for gas-phase structural biology
    Matthew F Bush
    Department of Chemistry, Physical and Theoretical Chemistry Laboratory, University of Oxford, South Parks Road, Oxford OX1 3QZ, UK
    Anal Chem 82:9557-65. 2010
    ..of highly accurate collision cross sections from traveling-wave ion mobility data through the use of calibration standards with similar masses and mobilities...
  12. ncbi Calibration and comparison of accelerometer cut points in preschool children
    Eveline Van Cauwenberghe
    Department of Movement and Sport Sciences, University of Ghent, Ghent, Belgium
    Int J Pediatr Obes 6:e582-9. 2011
    ..The present study aimed to develop accelerometer cut points to classify physical activities (PA) by intensity in preschoolers and to investigate discrepancies in PA levels when applying various accelerometer cut points...
  13. ncbi Calibration of serum creatinine in the National Health and Nutrition Examination Surveys (NHANES) 1988-1994, 1999-2004
    Elizabeth Selvin
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21287, USA
    Am J Kidney Dis 50:918-26. 2007
    The calibration of serum creatinine values to standardized creatinine and the commutability of serum creatinine across surveys are essential to the correct use of National Health and Nutrition Examination Survey (NHANES) data for kidney ..
  14. ncbi Validation and calibration of the Actical accelerometer in preschool children
    Karin A Pfeiffer
    Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
    Med Sci Sports Exerc 38:152-7. 2006
    ..The Actical accelerometer is a promising tool for measurement of PA in young children. The purpose of this study was to calibrate and validate the Actical accelerometer for use with 3- to 5-yr-old children...
  15. ncbi Calibration choice, rate smoothing, and the pattern of tetrapod diversification according to the long nuclear gene RAG-1
    Andrew F Hugall
    School of Earth and Environmental Sciences, University of Adelaide, SA, Australia
    Syst Biol 56:543-63. 2007
    ..Relaxed clock (PLRS) methods, using the amniote = 315 Mya (million years ago) calibration or a set of consistent calibrations, recovers reasonable divergence dates for most groups...
  16. pmc Assessment of physical activity using wearable monitors: recommendations for monitor calibration and use in the field
    Patty Freedson
    Department of Kinesiology, School of Public Health and Health Sciences, University of Massachusetts Amherst, Amherst, MA 01003, USA
    Med Sci Sports Exerc 44:S1-4. 2012
    ....
  17. pmc Quantitative guidelines for force calibration through spectral analysis of magnetic tweezers data
    Aartjan J W te Velthuis
    Department of BioNanoScience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, The Netherlands
    Biophys J 99:1292-302. 2010
    ..Using this simulator, we evaluate methods to correctly perform force experiments and provide guidelines for correct force calibration under configurations that can be encountered in typical magnetic tweezers experiments.
  18. ncbi Design and calibration of load sensing orthopaedic implants
    G Bergmann
    Julius Wolff Institut, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    J Biomech Eng 130:021009. 2008
    ..of instrumented implants is restricted by their small size, varying modes of load transfer, and the accuracy of calibration. Aims of this study were to test with finite element studies design features to improve the accuracy, to ..
  19. pmc The effect of inappropriate calibration: three case studies in molecular ecology
    Simon Y W Ho
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    PLoS ONE 3:e1615. 2008
    ..We illustrate this calibration problem using three case studies: avian speciation in the late Pleistocene, the demographic history of bowhead ..
  20. ncbi Design, calibration and pre-clinical testing of an instrumented tibial tray
    Bernd Heinlein
    Biomechanics Laboratory, Department of Orthopaedics, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, D 12203 Berlin, Germany
    J Biomech 40:S4-10. 2007
    ..The mean sampling rate is 125Hz. The calibration of the prosthesis resulted in an accuracy better than 2% mean measuring error...
  21. ncbi Calibration of accelerometer output for adults
    Charles E Matthew
    Department of Medicine, Division of General Internal Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA
    Med Sci Sports Exerc 37:S512-22. 2005
    This paper reviews the collective experience of monitor calibration studies in adults and seeks to answer the following questions: What has been done? What have we learned? What could be done to further enhance the comparability of ..
  22. ncbi Geological dates and molecular rates: fish DNA sheds light on time dependency
    Christopher P Burridge
    Department of Zoology, University of Otago, Dunedin, New Zealand
    Mol Biol Evol 25:624-33. 2008
    ..disruptions of linear freshwater systems and hence avoids many of the limitations associated with typical DNA calibration methods involving fossil data or island formation...
  23. ncbi Bayesian calibration of simultaneity in tactile temporal order judgment
    Makoto Miyazaki
    Advanced Research Center for Human Sciences, Faculty of Human Sciences, Waseda University, 2 579 15 Mikajima, Tokorozawa shi, Saitama 359 1192, Japan
    Nat Neurosci 9:875-7. 2006
    ..Here we report opposite perceptual changes that conform to a Bayesian integration theory in judging the order of two stimuli delivered one to each hand...
  24. pmc G-stack modulated probe intensities on expression arrays - sequence corrections and signal calibration
    Mario Fasold
    Interdisciplinary Centre for Bioinformatics, University Leipzig, Germany
    BMC Bioinformatics 11:207. 2010
    ..Probes with runs of at least three guanines (G) in their sequence show abnormal high intensities which reflect rather probe effects than target concentrations. This G-bias requires correction prior to downstream expression analysis...
  25. pmc Comparison and calibration of transcriptome data from RNA-Seq and tiling arrays
    Ashish Agarwal
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA
    BMC Genomics 11:383. 2010
    ..Understanding the relative merits of these technologies will help researchers select the appropriate technology for their needs...
  26. ncbi Calibration of an accelerometer during free-living activities in children
    Calum Mattocks
    Department of Social Medicine, University of Bristol, Bristol, UK
    Int J Pediatr Obes 2:218-26. 2007
    ..The aims of this study were to develop an equation to predict energy expenditure and to derive cut-points for moderate and vigorous physical activity intensity from the Actigraph accelerometer output in children aged 12 years...
  27. ncbi Assessing the predictive accuracy of QUICKI as a surrogate index for insulin sensitivity using a calibration model
    Hui Chen
    Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, Building 10, Room 6C 205, 10 Center Dr MSC 1632, Bethesda, MD 20892 1632, USA
    Diabetes 54:1914-25. 2005
    ..In the present study, we used a calibration model to compare the ability of QUICKI and other simple surrogates to predict SI(Clamp)...
  28. pmc Calibration of multiple poliovirus molecular clocks covering an extended evolutionary range
    Jaume Jorba
    Polio and Picornavirus Laboratory Branch, G 10, Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Virol 82:4429-40. 2008
    ....
  29. ncbi Co-adaptive calibration to improve BCI efficiency
    Carmen Vidaurre
    Machine Learning Department, Computer Science Faculty, Berlin Institute of Technology, Berlin, Germany
    J Neural Eng 8:025009. 2011
    ..Previously, we introduced the concept of machine learning based co-adaptive calibration, which provided substantially improved performance for a variety of users...
  30. pmc Calibration of self-reported oral health to clinically determined standards
    Honghu Liu
    Division of Public Health and Community Dentistry, UCLA School of Dentistry, Los Angeles, CA 90095 1668, USA
    Community Dent Oral Epidemiol 38:527-39. 2010
    ..We test hypotheses of trends across covariates, thereby creating optimal calibration models and tools that can adjust self-reported oral health to clinically determined standards.
  31. pmc Standardisation of data from real-time quantitative PCR methods - evaluation of outliers and comparison of calibration curves
    Malcolm J Burns
    Bio Molecular Innovation, LGC Limited, Queens Road, Teddington, Middlesex, TW11 0LY, UK
    BMC Biotechnol 5:31. 2005
    ..This paper presents two additional approaches for standardising data analysis through the novel application of statistical methods to RT-QPCR, in order to minimise potential uncertainty in results...
  32. ncbi The evaluation of the diet/disease relation in the EPIC study: considerations for the calibration and the disease models
    Pietro Ferrari
    International Agency for Research on Cancer IARC WHO, Lyon, France
    Int J Epidemiol 37:368-78. 2008
    ..This requires considerable work to standardize dietary measurements at the food and the nutrient levels...
  33. ncbi Estimation of markov chain transition probabilities and rates from fully and partially observed data: uncertainty propagation, evidence synthesis, and model calibration
    Nicky J Welton
    MRC Health Services Research Collaboration, Bristol, United Kingdom
    Med Decis Making 25:633-45. 2005
    ....
  34. pmc Straightforward, effective calibration of SPINAL-64 decoupling results in the enhancement of sensitivity and resolution of biomolecular solid-state NMR
    Gemma Comellas
    Center for Biophysics and Computational Biology, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    J Magn Reson 209:131-5. 2011
    ..Additionally, we also investigated the effect at higher spinning rate (33.3 kHz) and compared the results with other ¹H decoupling schemes (TPPM, XiX), as well as SPINAL-64 with the originally reported optimal values...
  35. pmc Calibrating ADL-IADL scales to improve measurement accuracy and to extend the disability construct into the preclinical range: a systematic review
    Robert A Fieo
    Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, UK
    BMC Geriatr 11:42. 2011
    ....
  36. ncbi Polarized light cues underlie compass calibration in migratory songbirds
    Rachel Muheim
    Department of Animal Ecology, Lund University, Ecology Building, SE 223 62 Lund, Sweden
    Science 313:837-9. 2006
    ..We suggest that skylight polarization patterns are used to derive an absolute (i.e., geographic) directional system that provides the primary calibration reference for all of the compasses of migratory songbirds.
  37. ncbi Electrochemical sensor for dopamine based on a novel graphene-molecular imprinted polymers composite recognition element
    Yan Mao
    Engineering Laboratory for Modern Analytical Techniques, c o State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Graduate University of the Chinese Academy of Sciences, Chinese Academy of Sciences, Changchun 130022, Jilin, PR China
    Biosens Bioelectron 28:291-7. 2011
    ..The new DA electrochemical sensor based on GSCR-MIPs composites also exhibited excellent repeatability, which expressed as relative standard deviation (RSD) was about 2.50% for 30 repeated analyses of 20 μM DA...
  38. ncbi Calibration of gamma camera systems for a multicentre European ¹²³I-FP-CIT SPECT normal database
    Livia Tossici-Bolt
    Department of Medical Physics and Bioengineering, Southampton University Hospitals NHS Trust, Tremona Road, Southampton SO16 6YD, UK
    Eur J Nucl Med Mol Imaging 38:1529-40. 2011
    ..This study describes the characterization and harmonization of the imaging equipment of the institutions involved...
  39. ncbi Validation and calibration of physical activity monitors in children
    Maurice R Puyau
    US Department of Agriculture, Agricultural Research Service Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
    Obes Res 10:150-7. 2002
    ....
  40. pmc Estimating plasma glucose from interstitial glucose: the issue of calibration algorithms in commercial continuous glucose monitoring devices
    Paolo Rossetti
    Instituto Universitario de Automatica e Informatica Industrial, Universidad Politecnica de Valencia, Camino de Vera, S N, 46022 Valencia, Spain
    Sensors (Basel) 10:10936-52. 2010
    ..This means that CGM need calibration against blood glucose values, and the accuracy of the estimation of blood glucose will also depend on the ..
  41. ncbi Calibration problems encountered while monitoring stump/socket interface pressures with force sensing resistors: techniques adopted to minimise inaccuracies
    A W Buis
    National Centre for Training and Education in Prosthetics and Orthotics, University of Strathclyde, Glasgow, Scotland, UK P P
    Prosthet Orthot Int 21:179-82. 1997
    ..Inaccuracies using FSRs have been reported. This paper summarises both the calibration problems encountered and the techniques adopted to minimise inaccuracies...
  42. ncbi Parameter estimation and optimal experimental design
    Julio R Banga
    IIM CSIC, Spanish Council for Scientific Research, C Eduardo Cabello 6, 36208 Vigo, Spain
    Essays Biochem 45:195-209. 2008
    ..the present chapter we review two key steps of the model building process, namely parameter estimation (model calibration) and optimal experimental design...
  43. ncbi Interlaboratory round robin on cantilever calibration for AFM force spectroscopy
    Joost Te Riet
    Scanning Probe Microscopy, Radboud University Nijmegen, P O Box 9010, 6500 GL Nijmegen, The Netherlands
    Ultramicroscopy 111:1659-69. 2011
    ..Hence, to calibrate cantilevers, a reliable calibration protocol is essential...
  44. ncbi Accuracy of the Enlite 6-day glucose sensor with guardian and Veo calibration algorithms
    Desmond Barry Keenan
    Medtronic Diabetes, R and D, Northridge, California 91325, USA
    Diabetes Technol Ther 14:225-31. 2012
    ..This study investigates the accuracy of a newly developed, next-generation subcutaneous glucose sensor, evaluated for 6-day use...
  45. ncbi Effect of calibration method on Tekscan sensor accuracy
    Jill M Brimacombe
    Department of Mechanical Engineering, University of British Columbia, 6250 Applied Science Lane, Vancouver, BC, V6R 2L7, Canada
    J Biomech Eng 131:034503. 2009
    ..While the overall accuracy of these sensors has been reported previously, the effects of different calibration algorithms on sensor accuracy have not been compared...
  46. ncbi Carbonate assignment and calibration in the Raman spectrum of apatite
    Ayorinde Awonusi
    Department of Chemistry, Central Michigan University, Mt Pleasant, MI 48859, USA
    Calcif Tissue Int 81:46-52. 2007
    ..The carbonate content of apatite was calibrated to a carbonate Raman band, and the method was used to determine the carbonate content of a sample of bovine cortical bone, 7.7 +/- 0.4%...
  47. pmc Development of robust calibration models using support vector machines for spectroscopic monitoring of blood glucose
    Ishan Barman
    Laser Biomedical Research Center, G R Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Anal Chem 82:9719-26. 2010
    Sample-to-sample variability has proven to be a major challenge in achieving calibration transfer in quantitative biological Raman spectroscopy...
  48. ncbi The Neuro/PsyGRID calibration experiment: identifying sources of variance and bias in multicenter MRI studies
    John Suckling
    Department of Psychiatry and Behavioural and Clinical Neurosciences Institute, Brain Mapping Unit, University of Cambridge, Cambridge, UK
    Hum Brain Mapp 33:373-86. 2012
    b>Calibration experiments precede multicenter trials to identify potential sources of variance and bias...
  49. ncbi Discrimination and calibration of mortality risk prediction models in interventional cardiology
    M E Matheny
    Decision Systems Group, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    J Biomed Inform 38:367-75. 2005
    Using a local percutaneous coronary intervention (PCI) data repository, we sought to compare the performance of a number of local and well-known mortality models with respect to discrimination and calibration.
  50. ncbi Standardization of the 24-hour diet recall calibration method used in the european prospective investigation into cancer and nutrition (EPIC): general concepts and preliminary results
    N Slimani
    Unit of Nutrition and Cancer, International Agency for Research on Cancer, Lyon, France
    Eur J Clin Nutr 54:900-17. 2000
    Despite increasing interest in the concept of calibration in dietary surveys, there is still little experience in the use and standardization of a common reference dietary method, especially in international studies...
  51. pmc Suppressing flashes of items surrounding targets during calibration of a P300-based brain-computer interface improves performance
    G E Frye
    East Tennessee State University, Johnson City, TN 37601, USA
    J Neural Eng 8:025024. 2011
    ..further examines the checkerboard paradigm by suppressing items which surround the target from flashing during calibration (i.e. the suppression condition)...
  52. ncbi Time-dependent rates of molecular evolution
    Simon Y W Ho
    Centre for Macroevolution and Macroecology, Evolution Ecology and Genetics, Research School of Biology, Australian National University, Canberra, ACT, Australia
    Mol Ecol 20:3087-101. 2011
    ..methodological factors that can cause rates to be time dependent, including the effects of natural selection, calibration errors, model misspecification and other artefacts...
  53. pmc Validity and calibration of food frequency questionnaires used with African-American adults in the Jackson Heart Study
    Teresa C Carithers
    Department of Family and Consumer Sciences, The University of Mississippi, University, USA
    J Am Diet Assoc 109:1184-1193. 2009
    ..To examine the relative validity of two food frequency questionnaires (FFQs) developed for use in investigating diet and disease relationships within the adult African-American population in the southern United States...
  54. ncbi Defocusing microscopy
    U Agero
    Departamento de Bioquimica e Imunologia, ICB, Universidade Federal de Minas Gerais Caixa Postal 489, Belo Horizonte, CEP 31270 910, MG, Brasil
    Microsc Res Tech 65:159-65. 2004
    ..The study of such fluctuations might be important for a better understanding of the engulfment process of pathogens during phagocytosis...
  55. ncbi HPLC-MS method for the quantification of nine anti-HIV drugs from dry plasma spot on glass filter and their long term stability in different conditions
    Antonio D'Avolio
    Laboratory of Clinical Pharmacology and Pharmacogenetics, Department of Infectious Diseases, University of Torino, Amedeo di Savoia Hospital, Corso Svizzera 164, 10149 Turin, Italy
    J Pharm Biomed Anal 52:774-80. 2010
    ....
  56. ncbi In situ calibration and [H+] sensitivity of the fluorescent Na+ indicator SBFI
    A Diarra
    Department of Anatomy, University of British Columbia, 2177 Westbrook Mall, Vancouver, British Columbia, Canada V6T 1Z3
    Am J Physiol Cell Physiol 280:C1623-33. 2001
    ..benzofuran isophthalate (SBFI) to measure intracellular free Na+ concentrations ([Na+](i)), the in situ calibration techniques described to date do not favor the straightforward determination of all of the constants required by ..
  57. pmc Comparing the performance of three generations of ActiGraph accelerometers
    Megan P Rothney
    Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA
    J Appl Physiol (1985) 105:1091-7. 2008
    ..Furthermore, the algorithms for energy expenditure predictions developed using older 7164 monitors may need to be modified for the GT1M...
  58. ncbi Rocks and clocks: calibrating the Tree of Life using fossils and molecules
    Philip C J Donoghue
    Department of Earth Sciences, University of Bristol, Bristol, BS8 1RJ, UK
    Trends Ecol Evol 22:424-31. 2007
    ..Reliably dated trees provide, for the first time, the opportunity to explore wider questions in macroevolution...
  59. pmc Mammographic density. Measurement of mammographic density
    Martin J Yaffe
    Imaging Research Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Breast Cancer Res 10:209. 2008
    ..In this article, the techniques for measurement of density are reviewed and some consideration is given to their strengths and limitations...
  60. ncbi A simple method to monitor and control methanol feeding of Pichia pastoris fermentations using mid-IR spectroscopy
    Jonas Schenk
    Laboratory of Chemical and Biochemical Engineering LGCB, Station 6 CH J2 503, Ecole Polytechnique Federale de Lausanne EPFL, CH 1015 Lausanne, Switzerland
    J Biotechnol 128:344-53. 2007
    ..However, complex and time-consuming calibration procedures are still required, and have inhibited the spreading of these instruments...
  61. ncbi Comparison of uncalibrated arterial pressure waveform analysis with continuous thermodilution cardiac output measurements in patients undergoing elective off-pump coronary artery bypass surgery
    Yong Bo Jeong
    Department of Anesthesiology and Pain Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
    J Cardiothorac Vasc Anesth 24:767-71. 2010
    ..a new device for arterial pressure waveform analysis for cardiac output (APCO) monitoring without external calibration, was developed...
  62. ncbi Actigraph calibration in obese/overweight and type 2 diabetes mellitus middle-aged to old adult patients
    Vitor Pires Lopes
    Dept of Sport Science, Polytechnic Institute of Braganca, Portugal
    J Phys Act Health 6:S133-40. 2009
    ..The purposes were: to calibrate Actigraph in middle-aged to old obese/overweight and DM2 adult patients; and to determine the threshold counts for sedentary, light, moderate, and vigorous physical activity (PA)...
  63. ncbi Validation, calibration, revision and combination of prognostic survival models
    H C van Houwelingen
    Department of Medical Statistics, Leiden University Medical Center, P O Box 9604, 2300 RC Leiden, The Netherlands
    Stat Med 19:3401-15. 2000
    ..Methods are sketched to perform validation through 'calibration', that is by embedding the literature model in a larger calibration model...
  64. pmc Accelerometer output and MET values of common physical activities
    Sarah L Kozey
    Department of Kinesiology, University of Massachusetts, 30 Eastman Lane, Amherst, MA 01003, USA
    Med Sci Sports Exerc 42:1776-84. 2010
    This article 1) provides the calibration procedures and methods for metabolic and activity monitor data collection, 2) compares measured MET values to the MET values from the compendium of physical activities, and 3) examines the ..
  65. pmc A systematic study of genome context methods: calibration, normalization and combination
    Luciana Ferrer
    Artificial Intelligence Center, SRI International, Menlo Park, California, USA
    BMC Bioinformatics 11:493. 2010
    ..Much work has been done in the application of these methods to different bioinformatics tasks, but few papers present a systematic study of the methods and their combination necessary for their optimal use...
  66. ncbi Analytical error reduction using single point calibration for accurate and precise metabolomic phenotyping
    Frans M van der Kloet
    TNO Quality of Life, P O Box 360, 3700 AJ Zeist, The Netherlands
    J Proteome Res 8:5132-41. 2009
    ..to control the analytical data quality without the availability of suitable labeled internal standards and calibration standards even within one laboratory...
  67. pmc Critical evaluation of methods used to determine amplification efficiency refutes the exponential character of real-time PCR
    Robert G Rutledge
    Natural Resources Canada, Canadian Forest Service, 1055 du PEPS, Quebec, Quebec G1V 4C7, Canada
    BMC Mol Biol 9:96. 2008
    ..Called "linear regression of efficiency" or LRE, this kinetic-based approach redefines amplification efficiency as the maximal efficiency (Emax) generated at the onset of thermocycling...
  68. ncbi Four well-constrained calibration points from the vertebrate fossil record for molecular clock estimates
    Johannes Muller
    Department of Biology, University of Toronto, Mississauga, ON, Canada
    Bioessays 27:1069-75. 2005
    Recent controversy about the use of the vertebrate fossil record for external calibration of molecular clocks centers on two issues, the number of dates used for calibration and the reliability of the fossil calibration date...
  69. pmc Appropriate calibration curve fitting in ligand binding assays
    John W A Findlay
    Pharmacokinetics, Dynamics, and Metabolism, Pfizer Global Research and Development, Groton, CT, USA
    AAPS J 9:E260-7. 2007
    b>Calibration curves for ligand binding assays are generally characterized by a nonlinear relationship between the mean response and the analyte concentration. Typically, the response exhibits a sigmoidal relationship with concentration...
  70. ncbi Comparison of different methods for lignin determination as a basis for calibration of near-infrared reflectance spectroscopy and implications of lignoproteins
    Kirsten Brinkmann
    Forstbotanisches Institut, Abtlg I Forstbotanik und Baumphysiologie, Georg August Universitat, Büsgenweg 2, 37077 Gottingen, Germany
    J Chem Ecol 28:2483-501. 2002
    ..Both NIRS calibration procedures gave good statistical fits with correlation coefficients close to 1, indicating that TGA and ADF ..
  71. pmc Accurate spectroscopic calibration for noninvasive glucose monitoring by modeling the physiological glucose dynamics
    Ishan Barman
    G R Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Anal Chem 82:6104-14. 2010
    ..problem for spectroscopic techniques, which predominantly probe ISF glucose, creating inconsistencies in calibration, where blood glucose measurements are used as a reference...
  72. pmc Cells lying on a bed of microneedles: an approach to isolate mechanical force
    John L Tan
    Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 100:1484-9. 2003
    ....
  73. pmc Evolutionary dynamics of the Pgk1 gene in the polyploid genus Kengyilia (Triticeae: Poaceae) and its diploid relatives
    Xing Fan
    Triticeae Research Institute, Sichuan Agricultural University, Sichuan, People s Republic of China
    PLoS ONE 7:e31122. 2012
    ....
  74. ncbi Performance comparison of accelerometer calibration algorithms based on 3D-ellipsoid fitting methods
    Matthias Gietzelt
    Peter L Reichertz Institute for Medical Informatics, University of Braunschweig Institute of Technology and Hannover Medical School, Muhlenpfordtstr 23, D 38106 Braunschweig, Germany
    Comput Methods Programs Biomed 111:62-71. 2013
    b>Calibration of accelerometers can be reduced to 3D-ellipsoid fitting problems...
  75. ncbi Calibration of the optical torque wrench
    Francesco Pedaci
    Department of BioNanoScience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands
    Opt Express 20:3787-802. 2012
    ..Quantitative torque measurements rely on an accurate calibration of the instrument...
  76. pmc A calibration protocol for population-specific accelerometer cut-points in children
    Kelly A Mackintosh
    Faculty of Education, Community and Leisure, Liverpool John Moores University, Liverpool, United Kingdom
    PLoS ONE 7:e36919. 2012
    ....
  77. ncbi Psychometric evaluation and calibration of health-related quality of life item banks: plans for the Patient-Reported Outcomes Measurement Information System (PROMIS)
    Bryce B Reeve
    National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Med Care 45:S22-31. 2007
    ..The construction and evaluation of item banks to measure unidimensional constructs of health-related quality of life (HRQOL) is a fundamental objective of the Patient-Reported Outcomes Measurement Information System (PROMIS) project...
  78. ncbi Optimizing the accuracy of a helical diode array dosimeter: a comprehensive calibration methodology coupled with a novel virtual inclinometer
    Jakub Kozelka
    Sun Nuclear Corp, Melbourne, FL 32940, USA
    Med Phys 38:5021-32. 2011
    ..This work introduces enhancements to the measurement accuracy of a 3D dosimeter comprised of a helical plane of diodes in a volumetric phantom...
  79. ncbi Key wavelengths screening using competitive adaptive reweighted sampling method for multivariate calibration
    Hongdong Li
    Research Center of Modernization of Traditional Chinese Medicines, College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, PR China
    Anal Chim Acta 648:77-84. 2009
    ..In each sampling run, a fixed ratio (e.g. 80%) of samples is first randomly selected to establish a calibration model...
  80. pmc Automatic chessboard detection for intrinsic and extrinsic camera parameter calibration
    Arturo de la Escalera
    Grupo de Sistemas Inteligentes, Universidad Carlos III de Madrid, Avda de la Universidad 30, 28911, Leganes, Madrid, Spain
    Sensors (Basel) 10:2027-44. 2010
    There are increasing applications that require precise calibration of cameras to perform accurate measurements on objects located within images, and an automatic algorithm would reduce this time consuming calibration procedure...
  81. ncbi A dual-respiration chamber system with automated calibration
    P F Schoffelen
    Department of Human Biology, Maastricht University, 6200 MD Maastricht, The Netherlands
    J Appl Physiol (1985) 83:2064-72. 1997
    This study characterizes respiration chambers with fully automated calibration. The system consists of two 14-m3 pull-type chambers...
  82. pmc Investigation of microdialysis sampling calibration approaches for lipophilic analytes: doxorubicin
    Gillian Whitaker
    Department of Chemistry, University of Kansas, RN Adams Institute for Bioanalytical Chemistry, 2030 Becker Drive, Lawrence, KS 66047, USA
    J Pharm Biomed Anal 53:490-6. 2010
    ..However, the only point in which no DOX was present in the perfusate was not on the no-net flux line. In addition, the transport of DOX across the microdialysis membrane was considerably slower than the transport of antipyrine...
  83. ncbi Correction of mass calibration gaps in liquid chromatography-mass spectrometry metabolomics data
    H Paul Benton
    Biomolecular Medicine, Department of Surgery and Cancer, Faculty of Medicine, Sir Alexander Fleming Building, Imperial College London, London, SW7 2AZ, UK
    Bioinformatics 26:2488-9. 2010
    ..Some manufacturers employ a mass calibration system that regularly switches between the analyte and a standard reference compound, and leads to gaps in the ..
  84. ncbi Adaptation minimizes distance-related audiovisual delays
    James Heron
    Department of Optometry, University of Bradford, Bradford, UK
    J Vis 7:5.1-8. 2007
    ..These effects demonstrate a novel functionality of temporal recalibration with clear ecological benefits...
  85. pmc Breast cancer risk estimation with artificial neural networks revisited: discrimination and calibration
    Turgay Ayer
    Industrial and Systems Engineering Department, University of Wisconsin, Madison, Wisconsin 53792 3252, USA
    Cancer 116:3310-21. 2010
    ..All studies have reported discrimination performance, but not one has assessed calibration, which is an equivalently important measure for accurate risk prediction...
  86. ncbi A new microparticle size calibration standard for use in measuring smaller microparticles using a new flow cytometer
    W L Chandler
    Department of Laboratory Medicine, University of Washington, Seattle, WA 98195, USA
    J Thromb Haemost 9:1216-24. 2011
    ..Microparticle size measurements are often calibrated on flow cytometers using polystyrene microspheres that forward scatter more light vs. particle diameter than cellular microparticles...
  87. pmc A quantitative collagen fibers orientation assessment using birefringence measurements: calibration and application to human osteons
    Ewa M Spiesz
    Institute of Lightweight Design and Structural Biomechanics, Vienna University of Technology, Vienna, Austria
    J Struct Biol 176:302-6. 2011
    ..The calibration curve was applied to human cortical bone osteons to quantify the out-of-plane collagen fibers arrangement...
  88. ncbi Utilization of a multiple antigenic peptide as a calibration standard in the BAN50 single antibody sandwich ELISA for Aβ oligomers
    Takashi Kasai
    Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602 0841, Japan
    Biochem Biophys Res Commun 422:375-80. 2012
    ..its practical application to large-scale or longitudinal studies has been limited because of lack of a reliable calibration standard...
  89. ncbi Review of measurement methods and clinical validation studies of noninvasive blood pressure monitors: accuracy requirements and protocol considerations for devices that require patient-specific calibration by a secondary method or device before use
    Kim Gau Ng
    Upper Iowa University, Singapore
    Blood Press Monit 16:291-303. 2011
    ..blood pressure (BP) monitors do not have specific provisions for monitors that require patient-specific calibration by a secondary method or device before use...
  90. pmc A focusing method in the calibration process of image sensors based on IOFBs
    Pedro R Fernández
    Electronics Department, Superior Polytechnic School, University of Alcala, Universitary Campus, Alcala de Henares 28871, Madrid, Spain
    Sensors (Basel) 10:47-60. 2010
    A focusing procedure in the calibration process of image sensors based on Incoherent Optical Fiber Bundles (IOFBs) is described using the information extracted from fibers...
  91. ncbi The extent and implications of sphygmomanometer calibration error in primary care
    A Rouse
    Department of Public Health and Epidemiology, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    J Hum Hypertens 15:587-91. 2001
    ..Its accuracy depends on correct maintenance and calibration. This study was designed to: (1) assess the maintenance and calibration of sphygmomanometers in use in primary ..
  92. pmc Requirements for calibration in noninvasive glucose monitoring by Raman spectroscopy
    Jan Lipson
    C8 MediSensors, Los Gatos, California, USA
    J Diabetes Sci Technol 3:233-41. 2009
    In the development of noninvasive glucose monitoring technology, it is highly desirable to derive a calibration that relies on neither person-dependent calibration information nor supplementary calibration points furnished by an existing ..
  93. pmc Unit-specific calibration of Actigraph accelerometers in a mechanical setup - is it worth the effort? The effect on random output variation caused by technical inter-instrument variability in the laboratory and in the field
    Niels C Moeller
    Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
    BMC Med Res Methodol 8:19. 2008
    Potentially, unit-specific in-vitro calibration of accelerometers could increase field data quality and study power...
  94. ncbi The human relevant potency threshold: reducing uncertainty by human calibration of cumulative risk assessments
    C J Borgert
    Applied Pharmacology and Toxicology, Inc, Gainesville, FL, USA
    Regul Toxicol Pharmacol 62:313-28. 2012
    ..The proposed approach recommends application of independent action for phthalates and other chemicals with potential anti-androgenic properties at current human exposure levels...
  95. ncbi Accurate technique for complete geometric calibration of cone-beam computed tomography systems
    Youngbin Cho
    Radiation Medicine Program, Princess Margaret Hospital, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada
    Med Phys 32:968-83. 2005
    ..Geometric calibration involves the estimation of a set of parameters that describes the geometry of such systems, and is essential ..
  96. pmc Direct and indirect haptic calibration of visual size judgments
    Monica Gori
    Robotics, Brain and Cognitive Sciences Department, Istituto Italiano di Tecnologia, Genova, Italy
    PLoS ONE 6:e25599. 2011
    It has long been suspected that touch plays a fundamental role in the calibration of visual perception, and much recent evidence supports this idea...
  97. ncbi Characterization of synthetic nucleic acids by electrospray ionization quadrupole time-of-flight mass spectrometry
    Herbert Oberacher
    Institute of Legal Medicine, Innsbruck Medical University, Muellerstrasse 44, 6020 Innsbruck, Austria
    J Mass Spectrom 40:932-45. 2005
    ..58 ppm and 3.06 ppm demonstrating the high stability of the applied external calibration. The molecular mass of a 51-mer was measured with a deviation smaller than 3.23 ppm from the theoretical value...
  98. pmc Design and instrumentation of a measurement and calibration system for an acoustic telemetry system
    Zhiqun Deng
    Pacific Northwest National Laboratory, P O Box 999, Richland, WA 99332, USA
    Sensors (Basel) 10:3090-9. 2010
    ..The objective of this study was to design and build a Measurement and Calibration System (MCS) for evaluating the JSATS components, because the JSATS requires comprehensive acceptance and ..
  99. ncbi Improved fMRI calibration: precisely controlled hyperoxic versus hypercapnic stimuli
    Clarisse I Mark
    McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada
    Neuroimage 54:1102-11. 2011
    The calibration of functional magnetic resonance imaging (fMRI) for the estimation of neuronal activation-induced changes in cerebral metabolic rate of oxygen (CMRO(2)) has been achieved through hypercapnic-induced iso-metabolic ..
  100. pmc Relaxivity-iron calibration in hepatic iron overload: probing underlying biophysical mechanisms using a Monte Carlo model
    Nilesh R Ghugre
    Division of Cardiology, Department of Radiology, Children s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California 90027 0034, USA
    Magn Reson Med 65:837-47. 2011
    ..Although recent work has demonstrated clinically valid estimates of human liver iron, the calibration varies with MRI sequence, field strength, iron chelation therapy, and organ imaged, forcing recalibration in ..
  101. pmc Multisensory calibration is independent of cue reliability
    Adam Zaidel
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 31:13949-62. 2011
    Multisensory calibration is fundamental for proficient interaction within a changing environment. Initial studies suggested a visual-dominant mechanism...

Research Grants75

  1. Novel TIRF microscopy analyzing trafficking & signaling at the cell cortex
    Derek Toomre; Fiscal Year: 2009
    ..circuits to control the galvometric XY mirror on our multi-angle FRAP/TIRFM (Aim 1B) and/or new auto-sensing calibration devices (Aim 2) or ii) Develop models or software to visualize and track vesicles in 3D by multi-angle TIRFM (..
  2. Advanced Magnetization Transfer Imaging in Multiple Sclerosis Disease
    Alexey Samsonov; Fiscal Year: 2012
    ..Truly quantitative MTI (qMTI) methods can circumvent these crippling deficiencies if rapid calibration and measurement of other MR parameters can be obtained in a reasonable scan time...
  3. Nutrition and Physical Activity Assessment Study (NPAAS)
    Ross L Prentice; Fiscal Year: 2013
    ..9TEE-REE as objective measure of AREE. We will develop calibration equations for each nutrient/food or activity measure having a suitable biomarker, by regression analysis of the ..
  4. Robust BCT for Clinical Use
    DAVID KOPPERDAHL; Fiscal Year: 2010
    ..computer vision, CT scanning, and biomechanics in order to develop an automated method of "phantomless" cross-calibration of CT scans for robust vertebral strength assessment...
  5. Patient-centered approaches to diagnosing coronary heart disease
    JOSEPH ABIODUN LADAPO; Fiscal Year: 2013
    ..benefit from additional training in advanced clinical decision-analysis, computer modeling techniques, model calibration, and validation...
  6. Novel Therapeutics in PTSD: A Randomized Clinical Trial of Mifepristone
    Gerardo Villarreal; Fiscal Year: 2013
    ..after drug discontinuation in these disorders, has led to the view that mifepristone's actions include re- calibration of a dysregulated HPA axis...
  7. 1H MRI based nanosensors for imaging tumor oxygenation
    Vikram D Kodibagkar; Fiscal Year: 2010
    ..months 7-12) Test nanoprobe stability in plasma over time and under variable pH conditions and obtain pO2 calibration curve as a function of temperature: Next, the stability of the synthesized nanoemulsions will be tested in a ..
  8. Plant-based diets and risk of cancer
    Gary E Fraser; Fiscal Year: 2013
    ..A large and comprehensive calibration study of 1011 representative subjects has been formed to validate the estimation of dietary intake, and also to ..
  9. Risk prediction of atrial fibrillation: clinical, biological and genetic markers
    EMELIA J contact BENJAMIN; Fiscal Year: 2010
    ..biomarkers, specifically natriuretic peptides or C-reactive protein enhance risk prediction (discrimination, calibration, reclassification) of AF when added to standard clinical factors;3...
  10. 10-Theory and Experiment for Genome Packaging in HBV Nucleocapsids
    JIANZHONG contact WU; Fiscal Year: 2010
    ..will create a synergy because, on the one hand, the scattering experiments provide necessary data for calibration of theoretical predictions and, on the other hand, computational results will further understanding the genome ..
  11. Validity of Diet and Activity Measures in Men
    Meir Stampfer; Fiscal Year: 2013
    ..Thus, NCI had requested proposals for a series of collaborative validation/calibration studies imbedded in existing cohorts using a common design with multiple self-reported and biomarker measures ..
  12. Use of Optogenetics to Assess the Role of Climbing Fibers in Motor Learning
    Rhea R Kimpo; Fiscal Year: 2013
    ..Research Project The execution of any skilled movement requires accurate calibration of the amplitude and timing of that movement...
  13. Cardiovascular Safety of Combination Therapies for Type 2 Diabetes Mellitus
    James S Floyd; Fiscal Year: 2013
    ..disease, adjustment for key potential confounding factors, analytic methods such as propensity score calibration, and sensitivity analyses will be used to address residual confounding, the most serious threat to the validity ..
  14. Pregnancy complications, future cardiovascular disease risk factors and cardiovas
    NISHA INDRAVADAN PARIKH; Fiscal Year: 2013
    ..the pregnancy factor risk score (developed in specific AIM 2) improves CVD risk stratification (discrimination, calibration and net reclassification) above and beyond established CVD risk factors among women using the VIP dataset ..
  15. Comparative effectiveness of noninvasive cardiac imaging
    Marcelo F Di Carli; Fiscal Year: 2010
    ..data comparing the clinical- and cost-effectiveness of noninvasive cardiac imaging with respect to diagnosis, calibration of future risk, and guiding management in patients with known or suspected CAD...
  16. WEARABLE SENSOR FOR CONTINUOUS NONINVASIVE MONITORING OF PULSE PRESSURE
    Sridhar Madala; Fiscal Year: 2010
    ..These measurements are input to an algorithm to estimate pulse pressure for each heartbeat without the need for calibration. The sensor can also estimate systolic, diastolic, and mean pressure with intermittent calibration against an ..
  17. Structural microenvironment of bone marrow stem cells
    FRANCESCO B RAMIREZ; Fiscal Year: 2013
    ..We previously demonstrated that osteopenia in MFS mice reflects perturbed bone remodeling due to impaired calibration of local anabolic and catabolic signals...
  18. Non-invasive neonatal respiration monitor
    ROSE MARIE VISCARDI; Fiscal Year: 2013
    ..However, these electrodes have many disadvantages: (1) They suffer from calibration drift due to depletion of the electrolyte;(2) lack of sensitivity at low O2 due to consumption of O2 by the ..
  19. Development of a Low Cost, Real-time Biofeedback Gait Retraining System
    SAUNDERS WHITTLESEY; Fiscal Year: 2012
    ..optically based 3D Motion Capture system using NaturalPoint Optitrack Flex:V100R2 cameras, ADtech's AMASS calibration and 3D reconstruction software...
  20. Clinical Validation of BCT - Phase II
    DAVID KOPPERDAHL; Fiscal Year: 2010
    ..to analyze CT scans acquired for any medical test with coverage of the hip and/or spine without an external calibration phantom...
  21. Clinical Evaluation of a Long Term Implanted Glucose Sensor
    JOSEPH Y LUCISANO; Fiscal Year: 2011
    ..pilot human clinical trials, and we will develop patient-friendly instructions for sensor operation, including calibration method and interval...
  22. Translational approaches to multilevel models of prenatal exposure to cigarettes
    Vanja Dukic; Fiscal Year: 2010
    ..This project is proposing to devise new Bayesian statistical models for prediction and calibration of smoking exposure measure, derived from combined biological and self-report information which can reflect ..
  23. Improving Methods for Comparative Effectiveness Research in Cardiovascular Care
    SOKO SETOGUCHI-IWATA; Fiscal Year: 2012
    ..propensity score using data mining techniques, B) instrumental variable analysis, and C) propensity score calibration to combat bias due to lack of detailed clinical information in claims data research assessing CE of therapies ..
  24. Cost-effective chronic disease prevention in developing countries
    JEREMY DAVID GOLDHABER-FIEBERT; Fiscal Year: 2013
    ..In order to determine model inputs, econometric regression and statistical calibration will be used.
  25. T Cell Signaling in Rheumatoid Arthritis
    Jorg J Goronzy; Fiscal Year: 2013
    ..We have found an increased responsiveness of the ERK pathway in RA T cells that is central to TCR calibration and amplifying signal strength and have proposed that mechanisms controlling the Raf-MEK-ERK module in T cells ..
  26. MEASUREMENT ERRORS IN ENVIRONMENTAL EPIDEMIOLOGY
    DONNA L SPIEGELMAN; Fiscal Year: 2013
    ..In the previous cycle of this project, we extended the regression calibration method for adjustment for measurement error in multivariate regression models, including Cox models and ..
  27. Identifying urinary biomarkers for early type 2 diabetic nephropathy
    Maryam Afkarian; Fiscal Year: 2013
    ..The preliminary data describes calibration and adaptation of a sensitive proteomic technology (iTRAQ: isobaric Tags for Relative and Absolute Quantitation)..
  28. Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension
    Flemming Forsberg; Fiscal Year: 2013
    ..Following calibration studies in the hepatic and portal veins of 3 canines, we will conduct a large scale clinical trial of the novel ..
  29. Optimizing localized therapy for primary liver cancer: a clinical trial and model
    REBECCA ANNE MIKSAD; Fiscal Year: 2013
    ..National OLT data, an institutional HCC database, and the literature will inform model parameters and model calibration. The effect of each liver directed strategy on overall survival (OS) and OLT wait list drop out will be ..
  30. Arterial Structure and Function and Atrial Fibrillation
    Lin Yee Chen; Fiscal Year: 2013
    ..discriminatory power of these novel risk factors, the extent to which these risk factors improve accuracy and calibration of predictive risk models, and the ability of these risk factors to improve risk classification...
  31. Modulating and Monitoring the Foreign Body Response to Implants
    Julie A Stenken; Fiscal Year: 2013
    ..The microdialysis probe will also be used to assess how device calibration and longevity is altered during the different treatments...
  32. Eye Movements: The Motor System that Sees the World
    Paul J May; Fiscal Year: 2011
    ..Motor Learning, Calibration, Plasticity, and Reward in the Oculomotor System, in which the roles of the cerebellum and basal ganglia in ..
  33. Continuous monitoring of anti-fibrinolytic therapy in cardiovascular surgery
    Francis G Spinale; Fiscal Year: 2012
    ..the use of microdialysis and microfluidics, the specific aims of this development project are (1) to complete calibration studies of a prototype and validated method to specifically and continuously measure PLact following ..
  34. X-Ray Fluorescence Computer Tomography with Emission Tomography Apertures
    LING JIAN MENG; Fiscal Year: 2011
    ..The techniques proposed here would provide calibration and subcellular localization information critical for the continued advancement of these technologies...
  35. TAS::75 0862::TAS
    Martin D Chapman; Fiscal Year: 2010
    ..will use monoclonal antibody pairs for allergen capture and detection and a standard of purified biomarkers for calibration purposes...
  36. Sensor-Enabled Elder Social Support Platform
    MARTIN LEWIS GRISS; Fiscal Year: 2010
    ..interfacing requirements, precision and interoperability, and 2) experimental validation of the attributes and calibration of the weights by integrating and evaluating a representative set of sensors into the Kinnexxus platform via a ..
  37. NK Cell Differentiation from Stem Cells
    Jeffrey S Miller; Fiscal Year: 2010
    ..The process of NK cell education is also referred to as licensing, calibration or arming/disarming...
  38. Biomarkers and Breast Cancer Risk Prediction in Younger Women
    Anne Zeleniuch-Jacquotte; Fiscal Year: 2013
    ..first degree relatives with a history of breast cancer), will be compared to the Gail model 2 with respect to calibration and discriminatory accuracy...
  39. A DNA biomarker of oral cancer metastasis
    Brian L Schmidt; Fiscal Year: 2013
    ..These documents, participant calibration, and the established committees will be the deliverables for the R34.
  40. Phenotype of urinary symptoms and relationships with genotype, sleep and obesity
    BRIAN TODD HELFAND; Fiscal Year: 2013
    ..Our methods include two aims: Instrument development/calibration;and clinical validation...
  41. RGR-based motion tracking for real-time adaptive MR imaging and spectroscopy
    THOMAS M ERNST; Fiscal Year: 2012
    ..D. (Medical College of Wisconsin) will be responsible for the overall engineering of the tracking and calibration system specifically within the confines of an MRI scanner. Oliver Speck, Ph.D...
  42. Magnetoresistive Sensor Platform for Parallel Cancer Marker Detection
    Marc D Porter; Fiscal Year: 2013
    ..g., noise and signal attributes, internal response calibration, design and layout of the addresses on the capture substrate array, separation between sensor (i.e...
  43. Portable Instrument for Chemifluorescent Detection of Lead in Dust
    JOAN STADER; Fiscal Year: 2011
    ..Phase I of this SBIR application are: (1) Assemble a functional benchtop prototype instrument with automated calibration capability, (2) Develop a robust standard protocol for use of the device to enable application for ..
  44. MRI Biometry of the Pseudophakic Cadaver Eye
    Susan A Strenk; Fiscal Year: 2010
    ..cadaver globes in order to fully characterize IOL placement in the anterior segment and to provide much needed calibration algorithms between our existing in vivo MRI biometry and cadaver biometry, since cadaver studies are routinely ..
  45. Photonic Crystal Enhanced Fluorescence: Development of Sensors Structures and Det
    Richard C Zangar; Fiscal Year: 2013
    ..To validate the new sensor and detection instrument, we will detect biomarkers spiked into plasma to establish calibration standards, directly compare against conventional ELISAs, and subsequently quantify biomarker concentrations in ..
  46. Discovery of exon, microRNA and clinical prognostic markers of glioblastoma survi
    SANDRA L RODRIGUEZ ZAS; Fiscal Year: 2010
    ..b>Calibration of the survival predictive equation will use cross-validation approaches and benchmarking to known markers of ..
  47. Development of a comprehensive model for colorectal cancer risk prediction
    Polly A Newcomb; Fiscal Year: 2013
    ..We will determine how well, in terms of calibration and predictive capacity, the model's predicted CRC risks (based on their baseline data) predict the CRC ..
  48. Novel Device for Sensitive, Small Sample Volume Assessment of Clot Elasticity
    Amy L Oldenburg; Fiscal Year: 2012
    ..modes are an intrinsic property of the specimen directly related to the CEM, the measurement requires no calibration procedures. Furthermore, there is no limitation to sample size, and measurement speeds <0.2s are anticipated...
  49. Esophageal Adenocarcinoma Policy Model: Trends, Risk Factors and Screening
    Chin Hur; Fiscal Year: 2013
    ..b>Calibration methodology will be used to systematically fine tune model parameters to produce targeted endpoints (e.g...
  50. Mapping pH at the surface of individual cell
    Yana K Reshetnyak; Fiscal Year: 2013
    ..selected, since it demonstrates shift of the emission spectra in response to pH, which solves the problem of calibration for the probe concentration. The probe will be attached to the N- or C- terminus of pHLIPs...
  51. HEART DISEASE IN RHEUMATOID ARTHRITIS
    Sherine E Gabriel; Fiscal Year: 2013
    ..g., Framingham) were of little value in RA, due to poor calibration (i.e., ability to predict absolute risk), and poor discrimination (i.e...
  52. Ambient PM2.5 and ETS exposure: interactive health effects for asthmatic children
    Matthew J Strand; Fiscal Year: 2010
    ..Using these, plus more unbiased measures of exposures from selected samples, regression calibration can be applied to yield estimates that are in similar and meaningful units of measurement...
  53. Calibrated ChIP-seq: determining local histone modification density genome-wide
    ALEXANDER JACKSON RUTHENBURG; Fiscal Year: 2013
    ..tag counts resulting from the exogenous semisynthetic nucleosome DNA series will serve as an internal-standard calibration curve for absolute quantification of mark density with the positional accuracy of ChIP-seq in a genome-wide ..
  54. PORTABLE IMAGING DEVICE FOR PROSTATE CANCER DETECTION
    Armen Sarvazyan; Fiscal Year: 2009
    ..As a separate component, an automatic calibration setup for tactile sensor testing, tuning and calibration will be designed and built...
  55. Multiphoton imaging and uncaging system with a capability of simultaneous electro
    Anders M Dale; Fiscal Year: 2010
    ..The requested system was chosen because of its high image quality, high acquisition speed, easy calibration of the two-photon imaging and uncaging optical pathways and compatibility with electrophysiology components...
  56. Continuous Glucose Monitoring with a Subcutaneous, Non-enzymatic Fluorescent Sens
    JEFF THOMAS SURI; Fiscal Year: 2011
    ..These limitations include inaccuracy in the hypoglycemic range, frequent calibration requirements, and long run-in times...
  57. High sensitivity Troponin T as a novel predictor of cardiovascular events
    ALEXIS LYNN BEATTY; Fiscal Year: 2012
    ..value of using hs-cTnT in addition to basic clinical measures by comparing discrimination (C statistic), calibration, and Net Reclassification Improvement (NRI) for predictive models with and without hs-cTnT...
  58. Survey and Test Platform for Use in Underserved Populations
    Gislin Dagnelie; Fiscal Year: 2012
    ..screen portable PC with an external flat screen, sound card, and earphones for stimulus presentation;screen calibration subsystem;and optional chin rest and gaze tracking subsystem...
  59. Quantitative Mapping of Molecules and Release Properties at Nerve Terminals
    TIMOTHY AIDAN RYAN; Fiscal Year: 2013
    ..b>Calibration procedures will allow us to determine the absolute number of these regulatory molecules at each nerve terminal ..
  60. Laser spectroscopic instrumentation for isotopic sensing of biogenic Nitric Oxide
    Gerard Wysocki; Fiscal Year: 2012
    ..2. Development, laboratory tests and implementation of reliable consumable-free calibration techniques, which will provide automatic and maintenance-free operation of the instrument. 3...
  61. Low Cost Laser Diagnostic for CD4+ T Cell Counting
    Michael J Lochhead; Fiscal Year: 2013
    ..We will develop a combination of calibration kit components and on-cartridge quality control features, including count calibrators, fluorescent stain ..
  62. Identification of Somatic Mutations in Rare Subclones of Solid Tumors
    Olivier Harismendy; Fiscal Year: 2012
    ..We will then precisely model the sequencing error using calibration samples to filter true mutations from the sequencing noise...
  63. MRI Biometry of the Pseudophakic Cadaver Eye
    Susan Strenk; Fiscal Year: 2007
    ..cadaver globes in order to fully characterize IOL placement in the anterior segment and to provide much needed calibration algorithms between our existing in vivo MRI biometry and cadaver biometry, since cadaver studies are routinely ..
  64. NEURAL CONTROL OF HUMAN VOLUNTARY MOVEMENTS
    Jerome Sanes; Fiscal Year: 2001
    ..during changing exigencies of voluntary motor action; (2) use somatic sensory inputs for muscle activity calibration needed for voluntary muscle activity...
  65. Peptide Biomarker Discovery by Mass Spectrometry for Early Detection of Liver Can
    Habtom Ressom; Fiscal Year: 2009
    ..The spectra from these studies will be used to optimize our peak detection/calibration and selection methods, and compare the methods with other existing solutions...
  66. Molecular Markers for Anopheles Gambiae Age Grading
    Guiyun Yan; Fiscal Year: 2009
    ..In order to adapt this new technique to An. gambiae, age-grading calibration models specifically for An...
  67. Ultra-soft atomic force microscope (USAFM) technology using nano-cantilevers for
    MEHDI YAZDANPANAH; Fiscal Year: 2009
    ..3. Experimental calibration and imaging under liquids: USPs fabricated on commercially- available AFM cantilevers will be tested in a ..
  68. MR of Heart Iron: T2*/T2 Calibration & Application
    Dudley Pennell; Fiscal Year: 2006
    ..These centers are Philadelphia (USA), Cagliari (Italy), Athens (Greece), Nicosia (Cyprus), Mumbai (India) and Singapore. ..
  69. SUBCUTANEOUS GLUCOSE BIOSENSORS
    Adam Heller; Fiscal Year: 1999
    ..are not fouled by cell growth; are calibrated, for the first time, in vivo by the long- sought one-point calibration. When the glucose concentration was monitored with pairs of the microwire sensors in rats and the sensors were ..
  70. OPTICAL PROBES OF LUNG VASCULAR ENDOTHELIAL FUNCTION
    Thomas Harris; Fiscal Year: 1993
    ..computerized multi- channel optical analyzer capable of measuring optical density in flowing blood; 3) perform calibration studies, studies of the effects of light scattering and comparisons of optical and radioactive tracer curves ..
  71. LEFT VENTRICLE OF THE DEVELOPING HEART
    Page Anderson; Fiscal Year: 1990
    ..Three LV dimensions will be used to derive in-vivo EDV, using a prolate ellipsoid model. In-vitro calibration will provide correction factors for the in-vivovivo data...
  72. Calibration Tools For PC-Based Vision Assessment
    Gislin Dagnelie; Fiscal Year: 2006
    ..This fault tolerance does not automatically extend to the setup and calibration of hardware, however...
  73. Multi-Resolution Corneal Topography (MRCT)
    EDWIN SARVER; Fiscal Year: 2006
    ..frame; 4) optical head enclosure; 5) system software; 6) mechanical interface to off-the-shelf manipulator; 7) calibration fixture and software. We will also evaluate performance of the system with test objects...
  74. Airway Navigational System
    JENELLE GANATRA; Fiscal Year: 2007
    ..B. Registration: We will refine our current fiduciary point based registration to an easier to use touchless calibration process...
  75. Development of a Handheld Transflectance Finger Noninvasive Glucose Monitor
    HANNU HARJUNMAA; Fiscal Year: 2007
    ..4) design a handheld system; 5) further enhance the glucose measurement algorithms; 6) achieve one point calibration; 7) build three handheld devices; and 8) test their performance with patients...