body size

Summary

Summary: The physical measurements of a body.

Top Publications

  1. pmc Life course variations in the associations between FTO and MC4R gene variants and body size
    Rebecca Hardy
    MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, University College London, 33 Bedford Place, London, UK
    Hum Mol Genet 19:545-52. 2010
  2. pmc Biology of the sauropod dinosaurs: the evolution of gigantism
    P Martin Sander
    Steinmann Institute, University of Bonn, Germany
    Biol Rev Camb Philos Soc 86:117-55. 2011
  3. pmc A single IGF1 allele is a major determinant of small size in dogs
    Nathan B Sutter
    National Human Genome Research Institute, Building 50, Room 5349, 50 South Drive MSC 8000, Bethesda, MD 20892 8000, USA
    Science 316:112-5. 2007
  4. pmc A simple genetic architecture underlies morphological variation in dogs
    Adam R Boyko
    Department of Genetics, Stanford School of Medicine, Stanford, California, United States of America
    PLoS Biol 8:e1000451. 2010
  5. ncbi Climate change and distribution shifts in marine fishes
    Allison L Perry
    Centre for Ecology, Evolution and Conservation, School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK
    Science 308:1912-5. 2005
  6. ncbi Declining body size: a third universal response to warming?
    Janet L Gardner
    Fenner School of Environment and Society, Australian National University, Canberra, ACT 0200, Australia
    Trends Ecol Evol 26:285-91. 2011
  7. ncbi The status of the world's land and marine mammals: diversity, threat, and knowledge
    Jan Schipper
    International Union for Conservation of Nature IUCN Species Programme, IUCN, 28 Rue Mauverney, 1196 Gland, Switzerland
    Science 322:225-30. 2008
  8. ncbi Multiple causes of high extinction risk in large mammal species
    Marcel Cardillo
    Division of Biology, Imperial College London, Silwood Park, Ascot SL5 7PY, UK
    Science 309:1239-41. 2005
  9. pmc Associations between phthalate metabolite urinary concentrations and body size measures in New York City children
    Susan L Teitelbaum
    Mount Sinai School of Medicine, Department of Preventive Medicine, One Gustave L Levy Place, Box 1057, NY 10029, USA
    Environ Res 112:186-93. 2012
  10. pmc Adaptation to aridity in the malaria mosquito Anopheles gambiae: chromosomal inversion polymorphism and body size influence resistance to desiccation
    Caroline Fouet
    Institut de Recherche pour le Developpement, UMR MIVEGEC, UM1, UM2, CNRS 5290, IRD 224, Montpellier, France
    PLoS ONE 7:e34841. 2012

Detail Information

Publications326 found, 100 shown here

  1. pmc Life course variations in the associations between FTO and MC4R gene variants and body size
    Rebecca Hardy
    MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, University College London, 33 Bedford Place, London, UK
    Hum Mol Genet 19:545-52. 2010
    ..Studies of the aetiology of obesity spanning different age groups may identify age-specific determinants of weight gain...
  2. pmc Biology of the sauropod dinosaurs: the evolution of gigantism
    P Martin Sander
    Steinmann Institute, University of Bonn, Germany
    Biol Rev Camb Philos Soc 86:117-55. 2011
    ..With body mass increase driven by the selective advantages of large body size, animal lineages will increase in body size until they reach the limit determined by the interplay of bauplan, ..
  3. pmc A single IGF1 allele is a major determinant of small size in dogs
    Nathan B Sutter
    National Human Genome Research Institute, Building 50, Room 5349, 50 South Drive MSC 8000, Bethesda, MD 20892 8000, USA
    Science 316:112-5. 2007
    The domestic dog exhibits greater diversity in body size than any other terrestrial vertebrate. We used a strategy that exploits the breed structure of dogs to investigate the genetic basis of size...
  4. pmc A simple genetic architecture underlies morphological variation in dogs
    Adam R Boyko
    Department of Genetics, Stanford School of Medicine, Stanford, California, United States of America
    PLoS Biol 8:e1000451. 2010
    Domestic dogs exhibit tremendous phenotypic diversity, including a greater variation in body size than any other terrestrial mammal...
  5. ncbi Climate change and distribution shifts in marine fishes
    Allison L Perry
    Centre for Ecology, Evolution and Conservation, School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK
    Science 308:1912-5. 2005
    ..Further temperature rises are likely to have profound impacts on commercial fisheries through continued shifts in distribution and alterations in community interactions...
  6. ncbi Declining body size: a third universal response to warming?
    Janet L Gardner
    Fenner School of Environment and Society, Australian National University, Canberra, ACT 0200, Australia
    Trends Ecol Evol 26:285-91. 2011
    A recently documented correlate of anthropogenic climate change involves reductions in body size, the nature and scale of the pattern leading to suggestions of a third universal response to climate warming...
  7. ncbi The status of the world's land and marine mammals: diversity, threat, and knowledge
    Jan Schipper
    International Union for Conservation of Nature IUCN Species Programme, IUCN, 28 Rue Mauverney, 1196 Gland, Switzerland
    Science 322:225-30. 2008
    ..Marine mammals are also disproportionately poorly known. These data are made freely available to support further scientific developments and conservation action...
  8. ncbi Multiple causes of high extinction risk in large mammal species
    Marcel Cardillo
    Division of Biology, Imperial College London, Silwood Park, Ascot SL5 7PY, UK
    Science 309:1239-41. 2005
    ..from the way that species traits associated with vulnerability, such as low reproductive rates, scale with body size. In a broad-scale analysis of extinction risk in mammals, we find two additional patterns in the size ..
  9. pmc Associations between phthalate metabolite urinary concentrations and body size measures in New York City children
    Susan L Teitelbaum
    Mount Sinai School of Medicine, Department of Preventive Medicine, One Gustave L Levy Place, Box 1057, NY 10029, USA
    Environ Res 112:186-93. 2012
    To examine prospectively associations between urinary phthalate metabolite concentrations and body size measures in children.
  10. pmc Adaptation to aridity in the malaria mosquito Anopheles gambiae: chromosomal inversion polymorphism and body size influence resistance to desiccation
    Caroline Fouet
    Institut de Recherche pour le Developpement, UMR MIVEGEC, UM1, UM2, CNRS 5290, IRD 224, Montpellier, France
    PLoS ONE 7:e34841. 2012
    ..gambiae to xeric habitats, beyond the adaptive value conferred by a larger body size.
  11. pmc Maternal high-fat diet effects on third-generation female body size via the paternal lineage
    Gregory A Dunn
    Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6046, USA
    Endocrinology 152:2228-36. 2011
    ..We previously reported that maternal high-fat diet exposure in mice resulted in an increase in body size and reduced insulin sensitivity that persisted across two generations via both maternal and paternal lineages...
  12. ncbi Climate change affects marine fishes through the oxygen limitation of thermal tolerance
    Hans O Portner
    Alfred Wegener Institute for Polar and Marine Research, Animal Ecophysiology, Postfach 12 01 61, 27515 Bremerhaven, Germany
    Science 315:95-7. 2007
    ..Decrements in aerobic performance in warming seas will thus be the first process to cause extinction or relocation to cooler waters...
  13. ncbi Arsenic exposure during pregnancy and size at birth: a prospective cohort study in Bangladesh
    Anisur Rahman
    International Centre for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka, Bangladesh
    Am J Epidemiol 169:304-12. 2009
    ..14 (SE, 0.03) mm per 1 microg/L, respectively. No further negative effects were shown at higher levels of arsenic exposure. The indicated negative effect on birth size at a low level of arsenic exposure warrants further investigation...
  14. pmc Population-based resequencing of experimentally evolved populations reveals the genetic basis of body size variation in Drosophila melanogaster
    Thomas L Turner
    Ecology, Evolution, and Marine Biology Department, University of California Santa Barbara, Santa Barbara, California, USA
    PLoS Genet 7:e1001336. 2011
    b>Body size is a classic quantitative trait with evolutionarily significant variation within many species...
  15. ncbi Early bursts of body size and shape evolution are rare in comparative data
    Luke J Harmon
    Department of Biological Sciences, University of Idaho, Moscow, Idaho 83844, USA
    Evolution 64:2385-96. 2010
    ..Here, we use phylogenetic comparative data on body size and shape in a diversity of animal clades to test a key model of adaptive radiation, in which initially rapid ..
  16. ncbi Body size, energy metabolism and lifespan
    John R Speakman
    Aberdeen Centre for Energy Regulation and Obesity ACERO, School of Biological Sciences, University of Aberdeen, Aberdeen AB24 2TZ, Scotland, UK
    J Exp Biol 208:1717-30. 2005
    ..A potentially much better model to explore the links of body size, metabolism and ageing is to examine the intraspecific links...
  17. pmc Four loci explain 83% of size variation in the horse
    Shokouh Makvandi-Nejad
    Department of Clinical Sciences, Cornell University, Ithaca, New York, United States of America
    PLoS ONE 7:e39929. 2012
    Horse body size varies greatly due to intense selection within each breed. American Miniatures are less than one meter tall at the withers while Shires and Percherons can exceed two meters...
  18. ncbi Multiple routes to mammalian diversity
    Chris Venditti
    Department of Biological Sciences, University of Hull, Hull HU6 7RX, UK
    Nature 479:393-6. 2011
    ..Niches do not seem to fill up, and diversity seems to arise whenever, wherever and at whatever rate it is advantageous...
  19. ncbi A basal dromaeosaurid and size evolution preceding avian flight
    Alan H Turner
    Division of Paleontology, American Museum of Natural History, Central Park West at 79th Street, New York, NY 10024 5192, USA
    Science 317:1378-81. 2007
    ..A dinosaur from Mongolia represents the basal divergence within Dromaeosauridae. The taxon's small body size and phylogenetic position imply that extreme miniaturization was ancestral for Paraves (the clade including ..
  20. ncbi Body size and risk of colon and rectal cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC)
    Tobias Pischon
    Department of Epidemiology, German Institute of Human Nutrition DIfE, Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
    J Natl Cancer Inst 98:920-31. 2006
    ..This discrepancy may be related to differences in fat distribution between sexes or to the use of hormone replacement therapy (HRT) in women...
  21. ncbi Adaptive radiation of multituberculate mammals before the extinction of dinosaurs
    Gregory P Wilson
    Department of Biology, University of Washington, Seattle, Washington 98195 1800, USA
    Nature 483:457-60. 2012
    ..complexity, which relates to the range of diets, rose sharply in step with generic richness and disparity in body size. Moreover, maximum dental complexity and body size demonstrate an adaptive shift towards increased herbivory...
  22. ncbi The evolution of maximum body size of terrestrial mammals
    Felisa A Smith
    Department of Biology, MSC03 2020, University of New Mexico, Albuquerque, NM 87131, USA
    Science 330:1216-9. 2010
    ..Our compilation of maximum body size at the ordinal level by sub-epoch shows a near-exponential increase after the K/Pg...
  23. ncbi Drosophila short neuropeptide F regulates food intake and body size
    Kyu Sun Lee
    Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology, 52 Eoun dong, Yusong gu, Daejeon, 395 333, Korea
    J Biol Chem 279:50781-9. 2004
    ..Also, sNPF overexpression in nervous systems produced bigger and heavier flies. These findings indicate that the sNPF is expressed in the nervous systems to control food intake and regulate body size in Drosophila melanogaster.
  24. ncbi Biomechanical consequences of scaling
    Andrew A Biewener
    Concord Field Station, Department of Organismic and Evolutionary Biology, Harvard University, Old Causeway Road, Bedford, MA 01730, USA
    J Exp Biol 208:1665-76. 2005
    ..Other 'low stress' tendons have larger safety factors, indicating that their primary design is for stiffness to reduce the amount of stretch that their muscles must overcome when contracting to control movement...
  25. ncbi Bee foraging ranges and their relationship to body size
    Sarah S Greenleaf
    Department of Plant Pathology, University of California, One Shields Avenue, Davis, CA 95616, USA
    Oecologia 153:589-96. 2007
    ..We used data from 96 records of 62 bee species to determine whether body size predicts foraging distance...
  26. ncbi Body size and dispersal mode as key traits determining metacommunity structure of aquatic organisms
    T De Bie
    Laboratory of Aquatic Ecology and Evolutionary Biology, K U Leuven, Leuven, Belgium
    Ecol Lett 15:740-7. 2012
    ..patterning than small-bodied groups suggesting an increasing impact of dispersal limitation with increasing body size. Metacommunities of organisms with the ability to fly (i.e...
  27. pmc Analysis of copy number variants by three detection algorithms and their association with body size in horses
    Julia Metzger
    Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover, Bunteweg 17p, 30559, Hannover, Germany
    BMC Genomics 14:487. 2013
    ..The aim of this study was to perform a standard comparative evaluation of CNVs in horses using three different CNV detection programs and to identify genomic regions associated with body size in horses.
  28. pmc DNA methylation patterns in cord blood DNA and body size in childhood
    Caroline L Relton
    HNRC, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 7:e31821. 2012
    ..The goal of this study was to investigate whether DNA methylation levels at birth are associated with body size later in childhood.
  29. ncbi Body size, weight change, fat distribution and breast cancer risk in Hispanic and non-Hispanic white women
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, UT 84117, USA
    Breast Cancer Res Treat 102:85-101. 2007
    The incidence of breast cancer varies among women living in the Southwestern part of the US. We evaluate how body size influences breast cancer risk among these women.
  30. pmc Adult body size, hormone receptor status, and premenopausal breast cancer risk in a multiethnic population: the San Francisco Bay Area breast cancer study
    Esther M John
    Cancer Prevention Institute of California, Fremont, 94538, USA
    Am J Epidemiol 173:201-16. 2011
    Large body size has been associated with a reduced risk of premenopausal breast cancer in non-Hispanic white women. Data on other racial/ethnic populations are limited...
  31. pmc Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1
    Kevin T Jones
    Department of Physiology and Diabetes Center, University of California San Francisco, San Francisco, CA, USA
    PLoS Biol 7:e60. 2009
    ..These mutants display a mild developmental delay and decreased body size, but have increased lipid storage...
  32. pmc Prothoracicotropic hormone regulates developmental timing and body size in Drosophila
    Zofeyah McBrayer
    The Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA
    Dev Cell 13:857-71. 2007
    In insects, control of body size is intimately linked to nutritional quality as well as environmental and genetic cues that regulate the timing of developmental transitions...
  33. pmc Patterns of body size and adiposity among UK children of South Asian, black African-Caribbean and white European origin: Child Heart And health Study in England (CHASE Study)
    Claire M Nightingale
    Division of Community Health Sciences, St George s, University of London, London, UK
    Int J Epidemiol 40:33-44. 2011
    ..A total of 5887 children aged 9-10 years participated (response rate 68%), including 1345 white Europeans, 1523 South Asians and 1570 black African-Caribbeans...
  34. ncbi Factors associated with male mating success of the dengue vector mosquito, Aedes aegypti
    Alongkot Ponlawat
    Department of Entomology, Cornell University, Ithaca, New York 14853, USA
    Am J Trop Med Hyg 80:395-400. 2009
    We studied the effects of male Aedes aegypti age, body size, and density on mating success under laboratory and field conditions...
  35. pmc The scaling and temperature dependence of vertebrate metabolism
    Craig R White
    Environmental Biology, School of Earth and Environmental Sciences, The University of Adelaide, Adelaide, SA, 5005 Australia
    Biol Lett 2:125-7. 2006
    b>Body size and temperature are primary determinants of metabolic rate, and the standard metabolic rate (SMR) of animals ranging in size from unicells to mammals has been thought to be proportional to body mass (M) raised to the power of ..
  36. ncbi Relationships between body size and abundance in ecology
    Ethan P White
    Department of Biology and the Ecology Center, Utah State University, Logan, UT 84322, USA
    Trends Ecol Evol 22:323-30. 2007
    b>Body size is perhaps the most fundamental property of an organism and is related to many biological traits, including abundance...
  37. doi Paleontology. Sauropod gigantism
    P Martin Sander
    Division of Paleontology, Steinmann Institute, University of Bonn, D 53115 Bonn, Germany
    Science 322:200-1. 2008
  38. pmc Body size distribution of the dinosaurs
    Eoin J O'Gorman
    School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom
    PLoS ONE 7:e51925. 2012
    The distribution of species body size is critically important for determining resource use within a group or clade. It is widely known that non-avian dinosaurs were the largest creatures to roam the Earth...
  39. ncbi Genetic architecture supports mosaic brain evolution and independent brain-body size regulation
    Reinmar Hager
    Computational and Evolutionary Biology Group, Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Nat Commun 3:1079. 2012
    ..We also demonstrate that variation in brain size is independently regulated from body size. The allometric relations seen at higher phylogenetic levels are thus unlikely to be the product of strong ..
  40. pmc Influence of body size and body fat distribution on risk of uterine leiomyomata in U.S. black women
    Lauren A Wise
    Department of Epidemiology, Harvard School of Public Health, 1010 Commonwealth Avenue, Boston, MA 02215, USA
    Epidemiology 16:346-54. 2005
    ..We prospectively investigated the risk of self-reported uterine leiomyomata in relation to body mass index (BMI), weight change, height, waist and hip circumferences, and waist-to-hip ratio in a large cohort of U.S black women...
  41. ncbi Effects of body size and nutritional regimen on survival in adult Aedes albopictus (Diptera: Culicidae)
    Rui De Xue
    Anastasia Mosquito Control District, 500 Old Beach Road, St Augustine, FL 32085 1409, USA
    J Med Entomol 47:778-82. 2010
    The effects of adult body size and nutritional regimen on the mean lethal time (LT) to death for the 50th (LT50) and 90th centiles (LT90) of large and small male and female Aedes albopictus (Skuse) were determined in the laboratory...
  42. pmc Body size and the risk of ovarian cancer by hormone therapy use in the California Teachers Study cohort
    Alison J Canchola
    Cancer Prevention Institute of California, 2201 Walnut Avenue, Suite 300, Fremont, CA 94538, USA
    Cancer Causes Control 21:2241-8. 2010
    ..To investigate whether obesity and hormone therapy (HT) are associated with ovarian cancer risk among women in the California Teachers Study cohort...
  43. ncbi Small body size increases the regional differentiation of populations of tropical mantellid frogs (Anura: Mantellidae)
    Maciej Pabijan
    Division of Evolutionary Biology, Zoological Institute, Technical University of Braunschweig, Braunschweig, Germany
    J Evol Biol 25:2310-24. 2012
    ..We evaluated the contributions of five variables potentially influencing clade diversification (body size, reproductive mode, range size, microhabitat and skin texture) on mtDNA divergence and polymorphism among ..
  44. ncbi A review of body size and breast cancer risk in Hispanic and African American women
    Krystal R Sexton
    Division of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas School of Public Health, Houston, Texas, USA
    Cancer 117:5271-81. 2011
    ..Forty-five studies of body size and breast cancer risk in non-Hispanic whites were identified...
  45. pmc High diversity, low disparity and small body size in plesiosaurs (Reptilia, Sauropterygia) from the Triassic-Jurassic boundary
    Roger B J Benson
    Department of Earth Sciences, University of Cambridge, Cambridge, United Kingdom
    PLoS ONE 7:e31838. 2012
    ..Increase in both maximum and minimum body length early in plesiosaurian history suggests a driven evolutionary trend. However, Maximum-likelihood models suggest only passive expansion into higher body size categories.
  46. ncbi Body size and breast cancer prognosis in relation to hormone receptor and menopausal status: a meta-analysis
    Saroj Niraula
    Mount Sinai Hospital and Princess Margaret Hospital, Toronto, ON, Canada
    Breast Cancer Res Treat 134:769-81. 2012
    ..This has implications for studies of weight loss interventions in the adjuvant BC setting...
  47. ncbi Visual distortion of body size modulates pain perception
    Flavia Mancini
    Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, United Kingdom
    Psychol Sci 22:325-30. 2011
    ..These results demonstrate that pain perception depends on multisensory representations of the body and that visual distortions of body size modulate sensory components of pain.
  48. ncbi Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis
    Laura A E Hughes
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    Int J Epidemiol 41:1060-72. 2012
    How body size influences risk of molecular subtypes of colorectal cancer (CRC) is unclear. We investigated whether measures of anthropometry differentially influence risk of tumours according to BRAF c.1799T>A p...
  49. ncbi Intraspecific variation in body size and the rate of reproduction in female insects - adaptive allometry or biophysical constraint?
    David Berger
    Department of Zoology, Stockholm University, 106 91, Stockholm, Sweden
    J Anim Ecol 81:1244-58. 2012
    ..rate, defined as the investment in early reproduction in proportion to total potential, should decrease with body size within species. 2...
  50. ncbi Size assessment and growth control: how adult size is determined in insects
    Christen Kerry Mirth
    Department of Biology, University of Washington, Seattle, WA 98195, USA
    Bioessays 29:344-55. 2007
    ..Thus, the mechanisms that control growth rates converge on those assessing size to ensure that the larvae attain the appropriate size at metamorphosis...
  51. ncbi The evolution and distribution of species body size
    Aaron Clauset
    Santa Fe Institute, 1399 Hyde Park Rd, Santa Fe, NM 87501, USA
    Science 321:399-401. 2008
    The distribution of species body size within taxonomic groups exhibits a heavy right tail extending over many orders of magnitude, where most species are much larger than the smallest species...
  52. ncbi Longitudinal study on the role of body size in premenopausal breast cancer
    Karin B Michels
    Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 166:2395-402. 2006
    ..A high body mass index (BMI) has been related to a reduced risk of breast cancer in premenopausal women. The mechanisms underlying this association have not been elucidated...
  53. pmc Regulation of genes affecting body size and innate immunity by the DBL-1/BMP-like pathway in Caenorhabditis elegans
    Andrew F Roberts
    Waksman Institute, Department of Molecular Biology and Biochemistry, Cancer Institute of New Jersey, Rutgers University, Piscataway, NJ 08854 8020, USA
    BMC Dev Biol 10:61. 2010
    ..In C. elegans, a BMP-like pathway, the DBL-1 pathway, controls body size and is involved in innate immunity...
  54. ncbi Global biogeography and ecology of body size in birds
    Valerie A Olson
    Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath, UK
    Ecol Lett 12:249-59. 2009
    ..We generate global maps of avian body size and demonstrate a general pattern of larger body sizes at high latitudes, conforming to Bergmann's rule...
  55. ncbi Global patterns in predator-prey size relationships reveal size dependency of trophic transfer efficiency
    Carolyn Barnes
    Centre for Environment, Fisheries and Aquaculture Science, Lowestoft, Suffolk NR33 0HT, United Kingdom
    Ecology 91:222-32. 2010
    Predator-prey body size relationships influence food chain length, trophic structure, transfer efficiency, interaction strength, and the bioaccumulation of contaminants...
  56. pmc Speciation in little: the role of range and body size in the diversification of Malagasy mantellid frogs
    Katharina C Wollenberg
    Department of Organismic and Evolutionary Biology and Museum of Comparative Zoology, Harvard University, 26 Oxford St, Cambridge, MA 02134, USA
    BMC Evol Biol 11:217. 2011
    ..near-complete species-level timetree of the Mantellidae with georeferenced distribution records and maximum male body size data to infer the influence of these life-history traits on each other and on mantellid diversification.
  57. ncbi Body size, body composition and fat distribution: comparative analysis of European, Maori, Pacific Island and Asian Indian adults
    Elaine C Rush
    Faculty of Health and Environmental Sciences, Centre for Physical Activity and Nutrition Research, AUT University, Private Bag 92006, Auckland 1020, New Zealand
    Br J Nutr 102:632-41. 2009
    ..The use of universal BMI cut-off points may not be appropriate for the comparison of obesity prevalence between ethnic groups...
  58. ncbi Consumer-resource body-size relationships in natural food webs
    Ulrich Brose
    Department of Biology, Darmstadt University of Technology, Darmstadt, Germany
    Ecology 87:2411-7. 2006
    It has been suggested that differences in body size between consumer and resource species may have important implications for interaction strengths, population dynamics, and eventually food web structure, function, and evolution...
  59. pmc The allometry of ornaments and weapons
    Astrid Kodric-Brown
    Department of Biology, University of New Mexico, Albuquerque, NM 87131, USA
    Proc Natl Acad Sci U S A 103:8733-8. 2006
    ..Both ornaments and weapons increase disproportionately with overall body size, resulting in scaling exponents within species that are consistently >1.0 and usually in the range 1.5-2.5...
  60. ncbi Developmental plasticity in the life history of a prosauropod dinosaur
    P Martin Sander
    Institut für Paläontologie, Universitat Bonn, Nussallee 8, D 53115 Bonn, Germany
    Science 310:1800-2. 2005
    ..growth stop) and quantitative (growth-mark counts) features of its histology are poorly correlated with body size. Individual life histories of P...
  61. ncbi BMI compared with 3-dimensional body shape: the UK National Sizing Survey
    Jonathan C K Wells
    Childhood Nutrition Research Centre and the Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London, United Kingdom
    Am J Clin Nutr 85:419-25. 2007
    ..Three-dimensional (3-D) body scanning provides high-quality digital information about shape...
  62. ncbi Body size of Smilodon (Mammalia: Felidae)
    Per Christiansen
    Department of Vertebrates, Zoological Museum, Copenhagen, Denmark
    J Morphol 266:369-84. 2005
    ..Particularly large specimens of S. populator almost certainly exceeded 400 kg in body mass. The differences from previous estimates are most likely caused by differences in the databases used for mass estimation...
  63. pmc Effect of physical activity and body size on survival after diagnosis with colorectal cancer
    A M M Haydon
    Department of Epidemiology and Preventive Medicine, Monash Medical School, Alfred Hospital, Melbourne 3004, Australia
    Gut 55:62-7. 2006
    ..Physical inactivity and obesity increase the risk of colorectal cancer but little is known about whether they influence prognosis after diagnosis...
  64. ncbi Predator-prey size relationships in an African large-mammal food web
    Norman Owen-Smith
    Centre for African Ecology, School of Animal, Plant and Environmental Sciences, University of the Witwatersrand, Wits 2050, South Africa
    J Anim Ecol 77:173-83. 2008
    ..Nevertheless, the large carnivore assemblage was dominated overwhelmingly by the largest predator, which contributed the major share of animals killed across a wide size range...
  65. ncbi Diabetes mellitus, body size and bladder cancer risk in a prospective study of Swedish men
    Susanna C Larsson
    Division of Nutritional Epidemiology, The National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Eur J Cancer 44:2655-60. 2008
    Epidemiologic studies on diabetes and body size in relation to risk of bladder cancer have yielded inconsistent results...
  66. ncbi Antagonistic actions of ecdysone and insulins determine final size in Drosophila
    Julien Colombani
    CNRS University of Nice Sophia Antipolis, UMR6543, Parc Valrose, 06108 Nice Cedex 2, France
    Science 310:667-70. 2005
    ..Hence, ecdysone counteracts the growth-promoting action of insulins, thus forming a humoral regulatory loop that determines organismal size...
  67. ncbi Allometric scaling of mammalian metabolism
    Craig R White
    School of Earth and Environmental Sciences, The University of Adelaide, Adelaide, SA, 5005 Australia
    J Exp Biol 208:1611-9. 2005
    ..Clearly the value of the exponent depends on the conditions under which the data are selected. The exponent for true BMR is 0.686 (+/-0.014), Tb normalised SMR is 0.675 (+/-0.013) and RMRt is 0.712 (+/-0.013)...
  68. ncbi Effects of body size and temperature on population growth
    Van M Savage
    Santa Fe Institute, Santa Fe, New Mexico 87501, USA
    Am Nat 163:429-41. 2004
    ..We use the theory to make explicit how and why rmax exhibits its characteristic dependence on body size and temperature...
  69. pmc Female red deer prefer the roars of larger males
    Benjamin D Charlton
    Department of Psychology, School of Life Sciences, University of Sussex, Brighton BN1 9QH, UK
    Biol Lett 3:382-5. 2007
    ..Here, we examine the response of female red deer (Cervus elaphus) to male roars in which an acoustic cue to body size, the formants, has been re-scaled to simulate different size callers...
  70. pmc Body size and risk of MS in two cohorts of US women
    Kassandra L Munger
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Neurology 73:1543-50. 2009
    ..To examine whether obesity during childhood, adolescence, or adulthood is associated with an increased risk of multiple sclerosis (MS)...
  71. ncbi High-quality male field crickets invest heavily in sexual display but die young
    John Hunt
    School of Biological, Earth and Environmental Sciences, The University of New South Wales, Sydney, New South Wales, 2052, Australia
    Nature 432:1024-7. 2004
    ..Moreover, they caution the use of longevity as a proxy for fitness in sexual selection studies, and suggest avenues for future research on the relationship between sexual attractiveness and ageing...
  72. ncbi Internal exposure to pollutants and body size in Flemish adolescents and adults: associations and dose-response relationships
    Willem Dhooge
    Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
    Environ Int 36:330-7. 2010
    Flanders is densely populated with much industry and intensive farming. Body size of 14- to 15-year old adolescents and of adults aged 50-65 was studied in relation to internal exposure to pollutants...
  73. ncbi Size and shape: the developmental regulation of static allometry in insects
    Alexander W Shingleton
    Department of Zoology, Michigan State University, 203 Natural Science, East Lansing, MI 48910, USA
    Bioessays 29:536-48. 2007
    Among all organisms, the size of each body part or organ scales with overall body size, a phenomenon called allometry...
  74. pmc The hormonal action of IGF1 in postnatal mouse growth
    Elias Stratikopoulos
    Department of Genetics and Development, Columbia University, 1150 St Nicholas Avenue, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 105:19378-83. 2008
    ..that the endocrine IGF1 plays a very significant role in mouse growth, as its action contributes approximately30% of the adult body size and sustains postnatal development, including the reproductive functions of both mouse sexes.
  75. ncbi Acute toxicity of crude oil water accommodated fraction on marine copepods: the relative importance of acclimatization temperature and body size
    Zhibing Jiang
    Key Laboratory of Marine Ecosystem and Biogeochemistry, Second Institute of Oceanography, State Oceanic Administration, Hangzhou, China
    Mar Environ Res 81:12-7. 2012
    ..01), and there was a significant (P < 0.05) positive correlation between the 48-h LC(50) and body size. Therefore, the small copepod species confront more survival challenges under oil contamination stress, ..
  76. ncbi The role of body size in individual-based foraging strategies of a top marine predator
    Michael J Weise
    Department of Ecology and Evolutionary Biology, University of California Santa Cruz, Center for Ocean Health, 100 Shaffer Rd, Santa Cruz, California 95060, USA
    Ecology 91:1004-15. 2010
    b>Body size is an important determinant of the diving and foraging ability in air-breathing marine vertebrate predators...
  77. pmc Sarcopenia definitions considering body size and fat mass are associated with mobility limitations: the Framingham Study
    Alyssa B Dufour
    Department of Biostatistics, Boston University School of Public Health, Massachusetts, USA
    J Gerontol A Biol Sci Med Sci 68:168-74. 2013
    ..Studies suggest that definitions should consider body size and additional influences of high fat mass (FM; sarcopenic-obesity)...
  78. ncbi Impact of iterative reconstruction on image quality and radiation dose in multidetector CT of large body size adults
    Gaurav S Desai
    Department of Abdominal Imaging and Intervention, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, White 270, Boston, MA 02114, USA
    Eur Radiol 22:1631-40. 2012
    ..To compare image quality and radiation dose using Adaptive Statistical Iterative Reconstruction (ASiR) and Filtered Back Projection (FBP) in patients weighing ≥ 91 kg...
  79. ncbi Growth and development rates have different thermal responses
    Jack Forster
    School of Biological and Chemical Sciences, Queen Mary University of London, United Kingdom
    Am Nat 178:668-78. 2011
    ..These predictions follow a concave relationship, which complicates attempts to model the impacts of increasing global temperatures on species body size.
  80. ncbi Alcohol consumption and risk of type 2 diabetes in European men and women: influence of beverage type and body size The EPIC-InterAct study
    J W J Beulens
    University Medical Center, Utrecht, The Netherlands
    J Intern Med 272:358-70. 2012
    ..To investigate the association between alcohol consumption and type 2 diabetes, and determine whether this is modified by sex, body mass index (BMI) and beverage type...
  81. ncbi The role of body size in host specificity: reciprocal transfer experiments with feather lice
    Sarah E Bush
    Department of Biology, University of Utah, 257 South 1400 East, Salt Lake City, Utah 84112, USA
    Evolution 60:2158-67. 2006
    ..Many different groups of host-specific parasites show a striking correlation between parasite and host body size, suggesting that size reinforces specificity...
  82. ncbi Allometry for sexual size dimorphism: testing two hypotheses for Rensch's rule in the water strider Aquarius remigis
    Daphne J Fairbairn
    Department of Biology, University of California, Riverside, California 92521, USA
    Am Nat 166:S69-84. 2005
    ..male secondary sexual traits and an alternative hypothesis that it is caused by greater phenotypic plasticity of body size in males...
  83. pmc Expression levels of LCORL are associated with body size in horses
    Julia Metzger
    Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover, Hannover, Germany
    PLoS ONE 8:e56497. 2013
    b>Body size is an important characteristic for horses of various breeds and essential for the classification of ponies concerning the limit value of 148 cm (58.27 inches) height at the withers...
  84. pmc Mammalian collection on Noah's Ark: the effects of beauty, brain and body size
    Daniel Frynta
    Department of Zoology, Faculty of Sciences, Charles University in Prague, Prague, Czech Republic
    PLoS ONE 8:e63110. 2013
    ..In agreement with various previous studies, we found that the body size and the attractiveness of mammals significantly affect all studied components of the mammalian collection of ..
  85. pmc Variation in metabolic rate of Anopheles gambiae and A. arabiensis in a Sahelian village
    Diana L Huestis
    Laboratory of Malaria and Vector Research, NIAID, NIH, 12735 Twinbrook Pkwy, Rockville, MD 20852, USA
    J Exp Biol 214:2345-53. 2011
    ..However, after accounting for their difference in body size, no significant difference in metabolic rate was found between these two species (whilst all other factors were ..
  86. ncbi A molecular phylogeny of nephilid spiders: evolutionary history of a model lineage
    Matjaz Kuntner
    Institute of Biology, Scientific Research Centre, Slovenian Academy of Sciences and Arts, Ljubljana, Slovenia Department of Entomology, National Museum of Natural History, Smithsonian Institution, Washington, DC, USA College of Life Sciences, Hubei University, Wuhan 430062, Hubei, China Electronic address
    Mol Phylogenet Evol 69:961-79. 2013
    ....
  87. pmc Healthy aging: is smaller better? - a mini-review
    Andrzej Bartke
    Department of Internal Medicine, Southern Illinois University School of Medicine, Springfield, 62794 9628, USA
    Gerontology 58:337-43. 2012
    ..of people with hereditary dwarfism revived interest in elucidating the relationships between growth, adult body size, age-related disease and longevity...
  88. ncbi A comparative analysis of the evolution of imperfect mimicry
    Heather D Penney
    Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, K1S 5B6, Canada
    Nature 483:461-4. 2012
    ..By contrast, a strong positive relationship between mimetic fidelity and body size supports the relaxed-selection hypothesis, suggesting that reduced predation pressure on less profitable prey ..
  89. ncbi Determinants of partial bird migration in the Amazon Basin
    Alex E Jahn
    Department of Biology, University of Florida, Gainesville, FL 32611 8525, USA
    J Anim Ecol 79:983-92. 2010
    ..sub-dominant individuals migrate at the end of the breeding season and dominant individuals do not, whereas the Body Size hypothesis predicts smaller individuals migrate and larger individuals do not. 4...
  90. pmc Effects of parental larval diet on egg size and offspring traits in Drosophila
    Roshan K Vijendravarma
    Department of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland
    Biol Lett 6:238-41. 2010
    ..However, they were slightly smaller as adults. Thus, the effects of parental diet on offspring performance under malnutrition apparently involve both adaptive plasticity and maladaptive effects of parental stress...
  91. ncbi Cues to body size in the formant spacing of male koala (Phascolarctos cinereus) bellows: honesty in an exaggerated trait
    Benjamin D Charlton
    Department of Cognitive Biology, University of Vienna, A 1090 Vienna, Austria
    J Exp Biol 214:3414-22. 2011
    ..and anatomical data to investigate whether male koala bellows provide reliable information on the caller's body size, and to confirm whether male koalas have a permanently descended larynx...
  92. pmc Mapping regions within cosmopolitan inversion In(3R)Payne associated with natural variation in body size in Drosophila melanogaster
    W Jason Kennington
    Centre for Evolutionary Biology, School of Animal Biology, The University of Western Australia, Crawley, Western Australia 6009, Australia
    Genetics 177:549-56. 2007
    ..have shown that this inversion strongly influences variation in wing size, a trait highly correlated with body size. We found three alleles from two separate regions within In(3R)Payne with significant additive effects on wing ..
  93. ncbi The SNP c.1326T>G in the non-SMC condensin I complex, subunit G (NCAPG) gene encoding a p.Ile442Met variant is associated with an increase in body frame size at puberty in cattle
    K Setoguchi
    Cattle Breeding Development Institute of Kagoshima Prefecture, Osumi, SO, Kagoshima, Japan
    Anim Genet 42:650-5. 2011
    ....
  94. pmc Resources and energetics determined dinosaur maximal size
    Brian K McNab
    Department of Zoology, University of Florida, Gainesville, FL 32611, USA
    Proc Natl Acad Sci U S A 106:12184-8. 2009
    ..The factors most responsible for setting the maximal body size of vertebrates are resource quality and quantity, as modified by the mobility of the consumer, and the ..
  95. ncbi Alcohol, smoking, and body size in relation to incident Hodgkin's and non-Hodgkin's lymphoma risk
    Unhee Lim
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Am J Epidemiol 166:697-708. 2007
    Studies associate alcohol consumption, cigarette smoking, and body size with the risk of overall or subtype lymphoma. Current data come mostly from case-control studies or prospective studies with few cases...
  96. pmc A computational analysis of limb and body dimensions in Tyrannosaurus rex with implications for locomotion, ontogeny, and growth
    John R Hutchinson
    Structure and Motion Laboratory, Department of Veterinary Basic Sciences, The Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom
    PLoS ONE 6:e26037. 2011
    ..Overall, the limb "antigravity" muscles may have been as large as or even larger than those of ratite birds, which themselves have the most muscular limbs of any living animal...
  97. ncbi Body size and growth in 0- to 4-year-old children and the relation to body size in primary school age
    T Stocks
    Department of Health Sciences, Faculty of Earth and Life Sciences and EMGO Institute for Health and Care Research, VU University, Amsterdam, The Netherlands
    Obes Rev 12:637-52. 2011
    ..The aim of this study was to review the literature on body size and growth in 0- to 4-year-old children and the association with body size at age 5-13 years...
  98. pmc Life-history evolution on tropidurinae lizards: influence of lineage, body size and climate
    Renata Brandt
    Departamento de Fisiologia, Instituto de Biociencias, Universidade de Sao Paulo, Sao Paulo, Brazil
    PLoS ONE 6:e20040. 2011
    ..including lizards, life history traits are plastic and relate to several sources of variation including body size, which is both a factor and a life history trait likely to modulate reproductive parameters...
  99. ncbi Size-spectra dynamics from stochastic predation and growth of individuals
    Richard Law
    Biology Department, University of York, P O Box 373, York YO105YW, United Kingdom
    Ecology 90:802-11. 2009
    ..described, is a traveling-wave solution in which waves move along the size spectrum from small to large body size. Traveling waves become more likely when predators prefer prey much smaller than themselves and when they are ..
  100. ncbi Diabetes awareness and body size perceptions of Cree schoolchildren
    Noreen D Willows
    Department of Agricultural, Food and Nutritional Science, School of Public Health, University of Alberta, Edmonton, Alberta, T6G 2P5, Canada
    Health Educ Res 24:1051-8. 2009
    ..A study was done to understand Cree schoolchildren's diabetes awareness and body size perceptions in two communities that had diabetes awareness-raising activities in the Province of Quebec, Canada...
  101. ncbi When Rensch meets Bergmann: does sexual size dimorphism change systematically with latitude?
    Wolf U Blanckenhorn
    Zoologisches Museum, Universitat Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
    Evolution 60:2004-11. 2006
    Bergmann's and Rensch's rules describe common large-scale patterns of body size variation, but their underlying causes remain elusive. Bergmann's rule states that organisms are larger at higher latitudes (or in colder climates)...

Research Grants72

  1. Structural and molecular basis of drug-induced IKACh reduction
    SAMI FOUAD NOUJAIM; Fiscal Year: 2012
    ..I obtained my PhD from the Department of Pharmacology at SUNY Syracuse in 2007. My thesis focused on ionic and body size determinants of ventricular fibrillation (VF) initiation and maintenance...
  2. Structural and molecular basis of drug-induced IKACh reduction
    SAMI FOUAD NOUJAIM; Fiscal Year: 2013
    ..I obtained my PhD from the Department of Pharmacology at SUNY Syracuse in 2007. My thesis focused on ionic and body size determinants of ventricular fibrillation (VF) initiation and maintenance...
  3. Neuropeptide modulation of biogenic amine function and aggression in a crustacean
    Maria A Sosa; Fiscal Year: 2013
    ..each animal assumes in the hierarchy of dominance is first determined by its morphotype rather than by its body size. There is ample evidence linking biogenic amines to behaviors associated with the establishment of social ..
  4. Monitoring of Cardiovascular Function in Infants By Transcutaneous Dye Dilution
    Istvan Seri; Fiscal Year: 2013
    ..measurements of cardiac function and circulating blood volume in critically ill neonates and infants whose small body size renders more invasive methods (pulmonary artery thermodilution catheter) technically challenging and associated ..
  5. Centrosomin and Centrosomes in Cell Division
    Timothy L Megraw; Fiscal Year: 2012
    ..like CDK5RAP2, Pericentrin, sas4 and Aspm, are the root cause of related syndromes that affect brain and/or body size, yet an understanding of the connection between function at the centrosome and the causes of disease are unclear...
  6. Control of developmental timing and body size in Drosophila
    MICHAEL BRENDAN O'CONNOR; Fiscal Year: 2013
    ..Altering the timing of many developmental processes can significantly affect an animals final body size, reproductive ability and ageing. In insects, timing of developmental transitions, i.e...
  7. Research and Mentoring on Energetic Factors and Cancer: Established Investigator
    Leslie Bernstein; Fiscal Year: 2013
    ..time (20% research, 20% mentoring) to pursue research with mentees on associations between physical activity and body size (using height, weight, waist and hip measurements, independently, and various ratio measures like body mass ..
  8. Effects of prenatal stress exposure on childhood physical and metabolic outcomes
    Kelsey Needham Dancause; Fiscal Year: 2013
    ..Controlling for confounding variables, I will examine relationships between level of stress exposure and body size, lean muscle and fat mass, and fat distribution patterns...
  9. Comparative Analysis of DNA Break Repair in Short- and Long-Lived Rodent Species
    Vera Gorbunova; Fiscal Year: 2012
    ..The data will be corrected for phylogenetic nonindependence, and controlled for confounding variables such as body size. Our laboratory is uniquely equipped to carry out the proposed research...
  10. Protein intake, nutrition and cardiovascular disease in stage V CKD
    Srinivasan Beddhu; Fiscal Year: 2011
    ..protein intake might improve nutritional status but it has been argued that the state of low muscle mass, small body size and low serum protein levels is not the result of decreased dietary intake, rather hypercatabolism induced by ..
  11. Gender differences in Bone Loss and Incident Fractures
    Elizabeth L Barrett Connor; Fiscal Year: 2010
    ..Using these data, we will 1) assess the age and sex related pattern of change in body size, lean body mass, BMD, NTX, bone size, bone geometry, and kyphotic posture, 2) assess the independent or co-..
  12. Exploring the Fuel-Mediated Programming of Neonatal Growth
    Dana Dabelea; Fiscal Year: 2013
    ..gestation and follow them prospectively through delivery in order to explore the relationships between maternal body size and behaviors during pregnancy [pre-pregnant BMI, weight gain, diet], intra-partum fuels (glucose, lipids, FFA), ..
  13. MSI-FLASH: An Exercise Intervention for Women with Menopausal Symptoms
    Barbara Sternfeld; Fiscal Year: 2012
    ..intervention, as will important protocol-specific variables, such as physical activity, physical fitness, and body size. The overall goal of MSI-FLASH is to accelerate the identification of effective remedies to relieve vasomotor ..
  14. LEGACY: A cohort of youth in families from the Breast Cancer Family Registry
    Mary Beth Terry; Fiscal Year: 2013
    ..of breast development), age at menarche, and breast tissue characteristics over time with childhood measures of body size, growth, lifestyle factors (physical activity, diet, vitamin D), built environment, and selected biomarkers of ..
  15. The role of mitochondrial energetics in adaptive thermogenesis with overfeeding
    DARCY LARAE JOHANNSEN; Fiscal Year: 2013
    ..overfeeding), or the ability to increase energy expenditure at rest out of proportion to the increase in body size, may be an important mechanism by which excess energy is dissipated to regulate body weight...
  16. LEGACY: A cohort of youth in families from the Breast Cancer Family Registry
    Irene Andrulis; Fiscal Year: 2013
    ..of breast development), age at menarche, and breast tissue characteristics over time with childhood measures of body size, growth, lifestyle factors (physical activity, diet, vitamin D), built environment, and selected biomarkers of ..
  17. Life Course Energy Balance and Breast Cancer Risk in Black/White Women Under 50
    Ellen M Velie; Fiscal Year: 2013
    ..by molecular tumor subtypes, but energy balance factors over the life course (growth patterns, onset of menses, body size, physical activity, diet and related genes) have been implicated...
  18. Using Community Based Participatory Research to Improve Health in Children
    LUISA contact SEIJO MALDONADO; Fiscal Year: 2010
    ..dependent variables in 3rd to 6th graders: attitudes, self-esteem, acceptance or lack of acceptance of body size, and self efficacy;and in adults we will measure stigmatization...
  19. Acid-base status and the development of hypertension and diabetes
    Eric N Taylor; Fiscal Year: 2012
    ..lower bicarbonate was associated with higher blood pressure and greater insulin resistance, independent of body size and kidney function...
  20. DYSREGULATION OF GLUCOSE HOMEOSTASIS IN AGING
    NIR J BARZILAI; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Throughout nature, a decrease in growth, and hence body size within species is associated with increased lifespan...
  21. Early life anthropometry, IGF pathway polymorphisms, and colorectal cancer risk
    Esther Wei; Fiscal Year: 2010
    ..in adulthood has been associated with increased risk of colorectal cancer, data evaluating the association body size in childhood and young adulthood and the risk of colorectal neoplasia are lacking...
  22. Suppression of tadpole limbs: a model for organ size regulation
    RICHARD ELINSON; Fiscal Year: 2009
    b>Body size can be altered by pituitary growth hormone, with the largest and smallest nonobese humans varying by about 10-fold in body mass...
  23. Epidemiology of Breast Cancer Subtypes in African American Women: a Consortium
    Julie R Palmer; Fiscal Year: 2013
    ..pregnancy history and lactation, and potential modification by genetic variants in related pathways;3) body size, early life and adult physical activity, and gene/environment interactions;and 4) risk factors that may have ..
  24. ENERGY BALANCE AND RISK OF BPH-RELATED OUTCOMES AND LUTS: A PROSPECTIVE STUDY
    Siobhan Sutcliffe; Fiscal Year: 2012
    ..Energy balance, measured as body size and physical activity (PA), shows promise as a modifiable cause of BPH/LUTS...
  25. The influence of the built environment on outcomes after breast cancer
    Theresa H M Keegan; Fiscal Year: 2010
    ..Some epidemiologic evidence suggests that body size and physical activity may be such modifiable factors and, moreover, that they are associated with community "..
  26. Integrating physiological and genetic mechanisms of body size regulation
    Viviane Callier; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Body size profoundly affects many aspects of animal biology, yet it remains one of the fundamental unsolved problems of developmental biology...
  27. Chemical Exposures and Infant Outcomes in the Neonatal Intensive Care Unit
    Annemarie Stroustrup; Fiscal Year: 2013
    ..newborns are particularly vulnerable to the effects of toxic chemicals in the environment because of their small body size, immature liver and kidney function, and rapid rate of development...
  28. Metabolic Adaptation After 2 Years of Caloric Restriction in Non-Obese Humans
    Eric Ravussin; Fiscal Year: 2012
    ..a metabolic adaptation (decrease in energy expenditure larger than accounted for by the decrease in metabolic body size) associated with a decrease in ROS-mediated oxidative damage...
  29. Genes, Hormomes, Growth, and Body Fat: Project HeartBeat
    DAVID MICHAEL HALLMAN; Fiscal Year: 2010
    ..genes from hormonal systems important in growth and development, emphasizing genes known or suspected to affect body size and body fat distribution...
  30. Genetic Mouse Models of Cartilage Healing
    LINDA J contact SANDELL; Fiscal Year: 2010
    ..Dr. Cheverud currently uses "super-healing" mice for studies on genes that contribute to body size and has developed 12 inbred strains of mice containing portions of the genome and an advanced intercross between ..
  31. In-Clinic Assessment of Organ Doses for Interventional Fluoroscopic Procedures
    DAVID BORREGO; Fiscal Year: 2013
    ..reference-point air kerma values and computational hybrid phantoms individually matched to the patient's body size and shape...
  32. The Genetics and Evolution of Extreme Body Size in Mice from Gough Island
    Bret A Payseur; Fiscal Year: 2013
    ..The largest wild house mice in the world reside on Gough Island;they have evolved extreme body size in just hundreds of generations...
  33. Childhood Origins for Cardiac Structure and Function
    Shumei S Sun; Fiscal Year: 2012
    ..specific aims that we plan to investigate include ascertaining the effects of children's blood pressure, body size, and body composition on (1) blood pressure, (2) cardiac structure, and (3) cardiac function in the same ..
  34. Stress History is Recorded in Tooth Enamel
    SHANE NEWPORT WHITE; Fiscal Year: 2012
    ..We have recently shown that an enamel biomarker corresponds to body size and to lamellar bone densitometry, confirming it as a surrogate for other important patterns of body regulation...
  35. The Genetics of Parallel Reproductive Isolation in Stickleback Species Pairs
    Catherine L Peichel; Fiscal Year: 2012
    ..Such behaviors are also contingent upon body size, shape, and ecological differences such as habitat, which therefore indirectly influence reproductive isolation...
  36. Body Size in Early Like and Insulin-Like Growth Factor in Adulthood
    HEATHER JOANNE BAER; Fiscal Year: 2010
    ..In particular, body size in early life - including birth weight and adiposity during childhood and adolescence - consistently has been ..
  37. Body size control genes & TGF-beta signaling C. elegans
    Cathy Savage Dunn; Fiscal Year: 2009
    ..In the nematode C. elegans, a TGFbeta-related signaling pathway, the dbl-1 pathway, controls body size and male tail morphogenesis...
  38. GWAS on childhood body fatness as an intermediate phenotype of breast cancer
    SARA LINDSTROEM; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Girls with large body size have a 15-30% reduced risk of developing breast cancer throughout life...
  39. Influence of Fasting Status and Specimen Processing Time on Adipokine Levels
    Howard D Strickler; Fiscal Year: 2012
    ..last meal and blood draw (fasting time) influences adipokine measurements, or how these effects may differ by body size. Second, delays in blood processing may accelerate degradation of these peptides;however, the extent of this ..
  40. Influence of Sociocultural Factors on Obesity
    KRISTIN NICOLE DUKES; Fiscal Year: 2010
    ..2007) indicates an association between SES and body image with individuals of lower SES holding a higher ideal body size than individuals of higher SES...
  41. Identifying Genome Wide SINE Retrotransposons Contributing to Dog Size Variation
    Nathan B Sutter; Fiscal Year: 2012
    ..provided functional sequence variation that enabled rapid diversification of traits under selection, such as body size. The rationale for the proposed research is that the dog's long history of intense selection under ..
  42. Anticancer Drug Pharmacology in Very Young Children
    Clinton F Stewart; Fiscal Year: 2013
    ..infants and young children with malignant brain tumors, the dosing of these toxic drugs is often scaled based on body size (e.g., BSA or body weight) or arbitrary age cut-offs...
  43. Systems Biology Approach to Growth Regulation in Cystic Fibrosis
    Mitchell L Drumm; Fiscal Year: 2012
    ..Survival of CF patients correlates strongly with body mass index, and mouse models indicate that body size in CF is due to a complex interaction of neuroendocrine function, adipose metabolism and intestinal function...
  44. Multilevel Longitudinal Models and Causal Networks for Childhood Obesity
    Shumei S Sun; Fiscal Year: 2012
    ..Repeated measurements of body size and composition from birth and frequent administration of questionnaires on lifestyle, diet, exercise and SES on ..
  45. The Developmental Origins of Disease and Deterioration in Old Age
    David J Barker; Fiscal Year: 2012
    ..The Helsinki Birth Cohort Study of 20,000 people is the only known data set in the world that includes maternal body size, birth size, infant and childhood growth and living conditions of people now at the end of their lives...
  46. NIH-FES-ASSISTED CYCLING TO IMPROVE FITNESS AND STRENGTH IN CHILDREN WITH CP
    Samuel C K Lee; Fiscal Year: 2013
    ..decline is the disparity that occurs when muscle strength gains due to growth are not commensurate to gains in body size or weight...
  47. Ectopic fat and atherosclerosis in South Asians
    Alka M Kanaya; Fiscal Year: 2013
    ..and adipokines between the South Asians and the four MESA ethnic groups after adjusting for age and overall body size. (2) To test the hypothesis that higher ectopic fat will be associated with worsened glucose tolerance;that ..
  48. Validation and Evaluation of a Portable Body Scanner for Determination of Obesity
    Jeanne Freeland Graves; Fiscal Year: 2009
    ..In sum, the non-contact, noninvasive nature of this new portable body scanner will produce a quick, inexpensive and objective measure of body size and type of obesity.
  49. Obesity and substance use: Identifying pathways and processes in adolescence
    HAYDEE ISABELLA LANZA; Fiscal Year: 2013
    ..ethnic and gender disparities in obesity prevalence and ethnic- and gender-specific associations between body size and social status may influence engagement in substance use...
  50. Fine mapping of mouse chr 2 for body composition genes
    DANIELLE RENEE REED; Fiscal Year: 2013
    ..One source of body size variation we have recently identified is a locus or cluster of loci on mouse chromosome 2 near 160 Mb...
  51. Systemic responses to tissue damage and regeneration
    Megumi M Fuse; Fiscal Year: 2013
    ..is modulated in response to external stresses, and how tissues interact to monitor changes in growth and body size during development...
  52. Relationship between adolescent weight, sexual behavior and reproductive outcomes
    Aletha Y Akers; Fiscal Year: 2012
    ..childhood obesity continue to rise, it is important that we develop a better understanding of how and for whom body size serves as a key contextual factor affecting adolescents'initiation and long-term perpetuation of sexual ..
  53. Genetics of leg size variation in insects
    ALEKSANDAR POPADIC; Fiscal Year: 2009
    Understanding the developmental processes by which organisms acquire their final body size is a fundamental biological question...
  54. Genetics and evolution of extreme body size in an island population of house mice
    MELISSA MARIE GRAY; Fiscal Year: 2012
    ..b>Body size has been especially well studied because of its central biological role and pervasive correlations with ..
  55. Impact of Environmental Pollutants on Breast Cancer and*
    Julia Brody; Fiscal Year: 2005
    ..to breast cancer risk -- ionizing radiation, family history, reproductive history, pharmaceutical hormones, body size, alcohol use, and lack of physical activity - but taken together these factors explain less than half of risk...
  56. PINEAL FUNCTION IN CHILDHOOD AND ADOLESCENCE
    Anita Cavallo; Fiscal Year: 1990
    ..melatonin concentrations (circadian and seasonal variations, cycles of light/dark and sleep/wake activity, body size, metabolic clearance rate) may account for many of the discrepancies in published data...
  57. Invasive Aedes Mosquitoes and Dengue in Brazil
    Leon Philip Lounibos; Fiscal Year: 2010
    ..competition in dengue-endemic areas of Rio de Janeiro, derives a surrogate measure of competition based on body size, and tests for effects of competition on adult longevity, another important variable affecting pathogen ..
  58. A Secular Change in Menstrual Characteristicis of Adult and Midlife Women?
    Sioban D Harlow; Fiscal Year: 2010
    ..Given the secular change in risk factors that influence menstrual function, including body size, smoking, parity and hormone use, evaluation of their impact on menstrual function is warranted...
  59. DIET, ACTIVITY & REPRODUCTION--RISKS FOR RECTAL CANCER
    MARTHA OR MARTY SLATTERY; Fiscal Year: 1999
    A case-control study to assess the independent and combined effects of dietary intake, physical activity, body size, reproductive factors, and family history on the risk of colon cancer in whites is proposed...
  60. High frequency auditory sensitivity in birds
    Bernard Lohr; Fiscal Year: 2004
    ..communication signals in birds, and secondarily to explore the effects of phylogenetic lineage and body size on sensitivity of the auditory system in birds...
  61. Choice, Control and Change: An inquiry-based science education
    Isobel Contento; Fiscal Year: 2009
    ..of the complex roles of biology and the 21st century food system in influencing personal behavior, health, and body size;(b) build skills and attitudes that lead to competence or personal control in navigating today's complex ..
  62. Technology to Improve Assessment of Physical Activity
    John Jakicic; Fiscal Year: 2005
    ..To assess whether variations in bodyweight and body size impact the accuracy of the KAL-X Sensor, we will recruit equal numbers of men and women from three body mass ..
  63. ANOREXIA NERVOSA: PREVALENCE, DETERMINANTS, TREATMENT
    PAUL GARFINKEL; Fiscal Year: 1980
    ..pressures to be thin, as exemplified by women who by career choice must focus increased attention on body size, would result in an increase in anorexia nervosa...
  64. OBESITY IN MEXICAN-AMERICAN CHILDREN
    JACQUELINE BLANK; Fiscal Year: 1992
    ..control over body weight as measured by scores on the Weight Locus of Control Scale? b) perceived ideal infant body size as measured by scores on the Ideal Infant Body Habitus Scale? 4) socioeconomic status as measured by Green's ..
  65. BIRTH WEIGHT EFFECT ON BLOOD PRESSURE IN LATE CHILDHOOD
    Bonita Falkner; Fiscal Year: 2001
    ..weight - high BP hypothesis, this concept is in conflict with the body of data on the association of BP with body size in childhood, adolescence, and adulthood which consistently demonstrates a direct relationship between body ..
  66. EARLY MALNUTRITION AND STATUS IN ADOLESCENCE
    Reynaldo Martorell; Fiscal Year: 1991
    ..Among these improvements are larger body size, greater working capacity, earlier maturation, and improved intellectual functioning and school achievement...
  67. Obesity, Physical Activity and Built Space in New York City
    Andrew Rundle; Fiscal Year: 2009
    We propose to investigate the impact of the built environment characteristics on body size, physical activity and diet in residents of New York City (NYC). We will use data from three large human health studies...
  68. Effects of Pregnancy on Adolescent Growth and Health
    Patricia Crawford; Fiscal Year: 2004
    ..Longitudinal studies of adolescents have not examined the effect of pregnancy on growth, body size, and blood lipid profiles since longitudinal data before, during and after pregnancy have not been available...
  69. Serum 25(OH)D, Vitamin D Intake, and Breast Cancer Recurrence in the WHEL Study
    Elizabeth T Jacobs; Fiscal Year: 2010
    ..intake of vitamin D and breast cancer recurrence;3) Explore whether calcium, vitamin A, carotenoids, or body size, modify the association between 25(OH)D and breast cancer recurrence using serum concentrations and dietary ..
  70. Accuracy of Physical Activity Measures in Cancer Studies
    Barbara Sternfeld; Fiscal Year: 2009
    ..with the PA diaries;3) aerobic capacity as determined from a sub-maximal graded exercise treadmill test;and 4) body size measurements (body mass index, % body fat from bioelectric impedance, and waist circumference)...