animal experimentation

Summary

Summary: The use of animals as investigational subjects.

Top Publications

  1. ncbi Should IACUCs review scientific merit of animal research projects?
    Michael D Mann
    IACUC, Nebraska Medical Center, Omaha, 68198 7830, USA
    Lab Anim (NY) 33:26-31. 2004
  2. ncbi Comments on the sixth report of the Animal Welfare Advisory Committee
    Sylvia Vaughan
    FRAME, Russell and Burch House, 96 98 North Sherwood Street, Nottingham NG1 4EE, UK
    Altern Lab Anim 31:207-12. 2003
  3. ncbi Ahimsa and alternatives -- the concept of the 4th R. The CPCSEA in India
    Shiranee Pereira
    Committee for the Purpose of Control and Supervision of Experiments on Animals, IN Chennai
    ALTEX 22:3-6. 2005
  4. ncbi Punctual professor using passé procedures. Contrary to the 3 Rs
    Pierre Freeman
    IACUC, IBC and Research Compliance and Training Officer, North Dakota State University, Fargo, ND, USA
    Lab Anim (NY) 35:18. 2006
  5. ncbi Making sense of multiple protocols and grant applications. Taking protocols for granted
    Torsten A Hopp
    Baylor College of Medicine, Houston, TX, USA
    Lab Anim (NY) 35:16. 2006
  6. ncbi A gold standard publication checklist to improve the quality of animal studies, to fully integrate the Three Rs, and to make systematic reviews more feasible
    Carlijn R Hooijmans
    Radboud University Nijmegen Medical Centre, Central Animal Laboratory and 3R Research Centre, Geert Grooteplein Noord 29, route 231, 6525 EZ Nijmegen, The Netherlands
    Altern Lab Anim 38:167-82. 2010
  7. pmc Where is the evidence that animal research benefits humans?
    Pandora Pound
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 328:514-7. 2004
  8. pmc Enhancing search efficiency by means of a search filter for finding all studies on animal experimentation in PubMed
    Carlijn R Hooijmans
    Radboud University Nijmegen Medical Centre, Central Animal Laboratory and 3R Research Centre, Geert Grooteplein Noord 29, route 231, Nijmegen, The Netherlands
    Lab Anim 44:170-5. 2010
  9. ncbi Animal experimentation in snake venom research and in vitro alternatives
    Paula G Sells
    Alistair Reid Venom Research Unit, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK
    Toxicon 42:115-33. 2003
  10. pmc How to become a top model: impact of animal experimentation on human Salmonella disease research
    Renee M Tsolis
    Department of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, One Shields Ave, Davis, CA 95661 8645, USA
    Infect Immun 79:1806-14. 2011

Detail Information

Publications252 found, 100 shown here

  1. ncbi Should IACUCs review scientific merit of animal research projects?
    Michael D Mann
    IACUC, Nebraska Medical Center, Omaha, 68198 7830, USA
    Lab Anim (NY) 33:26-31. 2004
    ..The authors examine this issue, discuss the pros and cons, suggest how IACUCs can go about reviewing protocols for scientific merit, and question what effect recent changes in regulations will have on this issue...
  2. ncbi Comments on the sixth report of the Animal Welfare Advisory Committee
    Sylvia Vaughan
    FRAME, Russell and Burch House, 96 98 North Sherwood Street, Nottingham NG1 4EE, UK
    Altern Lab Anim 31:207-12. 2003
    ....
  3. ncbi Ahimsa and alternatives -- the concept of the 4th R. The CPCSEA in India
    Shiranee Pereira
    Committee for the Purpose of Control and Supervision of Experiments on Animals, IN Chennai
    ALTEX 22:3-6. 2005
    ..This paper is about the Indian law on animal experimentation and the success story of the CPCSEA in India in inculcating the credo of 4Rs -- Replacement, Reduction, ..
  4. ncbi Punctual professor using passé procedures. Contrary to the 3 Rs
    Pierre Freeman
    IACUC, IBC and Research Compliance and Training Officer, North Dakota State University, Fargo, ND, USA
    Lab Anim (NY) 35:18. 2006
  5. ncbi Making sense of multiple protocols and grant applications. Taking protocols for granted
    Torsten A Hopp
    Baylor College of Medicine, Houston, TX, USA
    Lab Anim (NY) 35:16. 2006
  6. ncbi A gold standard publication checklist to improve the quality of animal studies, to fully integrate the Three Rs, and to make systematic reviews more feasible
    Carlijn R Hooijmans
    Radboud University Nijmegen Medical Centre, Central Animal Laboratory and 3R Research Centre, Geert Grooteplein Noord 29, route 231, 6525 EZ Nijmegen, The Netherlands
    Altern Lab Anim 38:167-82. 2010
    ..However, they are not yet widely used nor undertaken in the field of animal experimentation, even though there is a lot to be gained from the process...
  7. pmc Where is the evidence that animal research benefits humans?
    Pandora Pound
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 328:514-7. 2004
  8. pmc Enhancing search efficiency by means of a search filter for finding all studies on animal experimentation in PubMed
    Carlijn R Hooijmans
    Radboud University Nijmegen Medical Centre, Central Animal Laboratory and 3R Research Centre, Geert Grooteplein Noord 29, route 231, Nijmegen, The Netherlands
    Lab Anim 44:170-5. 2010
    ..SRs in laboratory animal science is the fact that searching for all available literature concerning animal experimentation is rather difficult...
  9. ncbi Animal experimentation in snake venom research and in vitro alternatives
    Paula G Sells
    Alistair Reid Venom Research Unit, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK
    Toxicon 42:115-33. 2003
    ..In the meantime, the principles of Reduce, Refine and Replace relating to animals in research are increasingly endorsed by those working in the field and the many agencies regulating ethical and research policy...
  10. pmc How to become a top model: impact of animal experimentation on human Salmonella disease research
    Renee M Tsolis
    Department of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, One Shields Ave, Davis, CA 95661 8645, USA
    Infect Immun 79:1806-14. 2011
    ..This article reviews important milestones in the use of animal models to study human Salmonella disease and identify research needs to guide future work...
  11. ncbi Systematic reviews and meta-analyses of preclinical studies: publication bias in laboratory animal experiments
    D A Korevaar
    Department of General Practice, Academic Medical Center AMC, University of Amsterdam UvA, PO Box 22700, 1100 DD Amsterdam, The Netherlands
    Lab Anim 45:225-30. 2011
    ..A statistically significant proportion of MAs considered publication bias (26/35) and tried to formally assess it (21/35)...
  12. ncbi Emergency medicine animal research: does use of randomization and blinding affect the results?
    Vik Bebarta
    University of Colorado Health Sciences Center, Denver 80262, USA
    Acad Emerg Med 10:684-7. 2003
    ....
  13. ncbi A systematic review of systematic reviews and meta-analyses of animal experiments with guidelines for reporting
    Jaime L Peters
    Centre for Biostatistics and Genetic Epidemiology, Department of Health Sciences, University of Leicester, Leicester, UK
    J Environ Sci Health B 41:1245-58. 2006
    ..Further consideration of the use and methodological quality and reporting of such studies is needed...
  14. ncbi The current status of animal use and alternatives in Korean veterinary medical schools
    Gwi Hyang Lee
    The Institute for the 3Rs, College of Veterinary Medicine, Konkuk University, Seoul, Korea
    Altern Lab Anim 38:221-30. 2010
    ..The information presented represents the first such data gathered in Korea, which should prove useful for monitoring the implementation of replacement, reduction, and refinement measures in animal use for education purposes...
  15. pmc Publication bias in laboratory animal research: a survey on magnitude, drivers, consequences and potential solutions
    Gerben Ter Riet
    Department of General Practice, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 7:e43404. 2012
    ..Publication bias jeopardizes evidence-based medicine, mainly through biased literature syntheses. Publication bias may also affect laboratory animal research, but evidence is scarce...
  16. pmc Methodological quality of systematic reviews of animal studies: a survey of reviews of basic research
    Luciano E Mignini
    Centro Rosarino de Estudios Perinatales, Rosario, Argentina
    BMC Med Res Methodol 6:10. 2006
    ..Systematic reviews can serve as a tool in translation of basic life sciences research from laboratory to human research and healthcare. The extent to which reviews of animal research are systematic and unbiased is not known...
  17. ncbi Assessing the search for and implementation of the Three Rs: a survey among scientists
    Marlies Leenaars
    Radboud University Nijmegen Medical Centre, Central Animal Laboratory, Nijmegen, The Netherlands
    Altern Lab Anim 37:297-303. 2009
    ....
  18. ncbi Progress in animal experimentation ethics: a case study from a Brazilian medical school and from the international medical literature
    Edvaldo Luiz Ramalli Jr
    Faculty of Medicine of Ribeirao Preto, USP, Sao Paulo, Brazil
    Acta Cir Bras 27:659-63. 2012
    ..This study describes in Brazil and in the global biomedical community the time course of the development of animal research welfare guidelines...
  19. ncbi Reducing animal experimentation in foot-and-mouth disease vaccine potency tests
    Richard Reeve
    Boyd Orr Centre for Population and Ecosystem Health, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom
    Vaccine 29:5467-73. 2011
    ....
  20. pmc Factors influencing the effectiveness of research ethics committees
    C A Schuppli
    Animal Welfare Program, University of British Columbia, 2357 Main Hall, Vancouver, British Columbia, V6T 1Z4, Canada
    J Med Ethics 33:294-301. 2007
    ..These results, together with results from the literature on research ethics committees, suggested potential ways to improve the effectiveness of research ethics committees...
  21. ncbi The great primate debate
    Sally Goodman
    Nature 417:684-7. 2002
  22. ncbi [Alternatives to animal experimentation v.s. animal rights terrorism]
    Tsutomu Miki Kurosawa
    The Institue of Experimental Animal Sciences, Osaka University Medical School, Suita City, Japan
    Yakugaku Zasshi 128:741-6. 2008
    Systematic modern animal experimentation was established by Bernard Claude who wrote "An Introduction to the Study of Experimental Medicine" in 1865...
  23. pmc Refining animal models in fracture research: seeking consensus in optimising both animal welfare and scientific validity for appropriate biomedical use
    Jorg A Auer
    Equine Hospital, Vetsuisse Faculty University of Zurich, Zurich, Switzerland
    BMC Musculoskelet Disord 8:72. 2007
    ....
  24. ncbi Alternatives to animal experimentation in biomedical education
    Franz P Gruber
    FFVFF, CH Zuerich
    ALTEX 21:33-48. 2004
    ..The global situation is probably worse with animals still being used in high school teaching in some countries such as the USA...
  25. ncbi Towards ethically improved animal experimentation in the study of animal reproduction
    D Blache
    UWA Institute of Agriculture M082, The University of Western Australia, Crawley, WA, Australia
    Reprod Domest Anim 43:8-14. 2008
    ..The outcome is a better experimental design, on both ethical and scientific grounds...
  26. ncbi Adaptation to stress induced by restraining rats and mice in nose-only inhalation holders
    Sandy P Narciso
    Department of Environmental Medicine, New York University School of Medicine, Tuxedo, New York 10987, USA
    Inhal Toxicol 15:1133-43. 2003
    ..Rats and mice restrained for 4 h/day every day showed a gradual decrease in heart rate and temperature over time. Full adaptation to restraint required 14 days of fixed-duration daily restraint...
  27. ncbi Potential for unintended consequences of environmental enrichment for laboratory animals and research results
    Kathryn Bayne
    AAALAC International, Hilo, HI, USA
    ILAR J 46:129-39. 2005
    ....
  28. pmc Does animal experimentation inform human healthcare? Observations from a systematic review of international animal experiments on fluid resuscitation
    Ian Roberts
    Cochrane Injuries Group, Public Health Intervention Research Unit, London School of Hygiene and Tropical Medicine, London WC1B 3DP
    BMJ 324:474-6. 2002
  29. ncbi Why are so many epidemiology associations inflated or wrong? Does poorly conducted animal research suggest implausible hypotheses?
    Michael B Bracken
    School of Public Health and Medicine, Yale University, New Haven, CT, USA
    Ann Epidemiol 19:220-4. 2009
    ....
  30. ncbi Different views on ethics: how animal ethics is situated in a committee culture
    M Ideland
    Malmo University, Sweden
    J Med Ethics 35:258-61. 2009
    Research that includes non-human animal experimentation is fundamentally a dilemmatic enterprise. Humans use other animals in research to improve life for their own species. Ethical principles are established to deal with this dilemma...
  31. pmc Are animal models predictive for humans?
    Niall Shanks
    Americans for Medical Advancement, 2251 Refugio Rd Goleta, CA 93117, USA
    Philos Ethics Humanit Med 4:2. 2009
    ..This is not surprising considering what we have learned from fields such evolutionary and developmental biology, gene regulation and expression, epigenetics, complexity theory, and comparative genomics...
  32. pmc Is the use of sentient animals in basic research justifiable?
    Ray Greek
    Americans for Medical Advancement, Goleta, CA 93117, USA
    Philos Ethics Humanit Med 5:14. 2010
    ..We conclude that the use of sentient animals in basic research cannot be justified in light of society's priorities...
  33. pmc Surveying the literature from animal experiments: systematic review and meta-analysis are important contributions
    Malcolm R Macleod
    BMJ 331:110. 2005
  34. ncbi Animal experiments under fire for poor design
    Jim Giles
    Nature 444:981. 2006
  35. ncbi Animal research ethics in Africa: an overview
    Aceme Nyika
    African Malaria Network Trust AMANET, Dar es Salaam, Tanzania
    Acta Trop 112:S48-52. 2009
    ..globally that has led to the development of guidelines and in some instances national laws governing animal experimentation. Although there may not be empirical data on the existence or adequacy of national and/or institutional ..
  36. ncbi Biomedical research. The endangered lab chimp
    Jon Cohen
    Science 315:450-2. 2007
  37. pmc The ethics of animal experimentation
    Bernard A Foex
    Manchester Royal Infirmary, Oxford Road Manchester, M13 9WL, UK
    Emerg Med J 24:750-1. 2007
  38. ncbi Animal ethical evaluation: an observational study of Canadian IACUCs
    Lise Houde
    Departement de Psychologie, Universite du Quebec a Montreal, C P 8888 Succ C V, Montreal, QC, Canada, H3C 3P8
    Ethics Behav 13:333-50. 2003
    ..The results are discussed in relation to previous nonobservational research that identified potential pitfalls and bias in animal ethical evaluation...
  39. ncbi The '3Rs' model and the concept of alternatives in animal research: a questionnaire survey
    Simone Pollo
    Dipartimento di Studi Filosofici e Epistemologici, Universita di Roma La Sapienza, Rome, Italy
    Lab Anim (NY) 33:47-53. 2004
    ..The authors used a questionnaire survey to determine how well-known experts judged issues related to the 3Rs...
  40. ncbi Animal experimentation
    Roman Kolar
    Animal Welfare Academy Akademie für Tierschutz, German Animal Welfare Federation Deutscher Tierschutzbund, Spechtstr 1, 85579 Neubiberg, Germany
    Sci Eng Ethics 12:111-22. 2006
    ..Legislation of animal experimentation in modern societies is based on the supposition that this is ethically acceptable when certain more or ..
  41. ncbi Research ethics I: Responsible conduct of research (RCR)--historical and contemporary issues pertaining to human and animal experimentation
    Jennifer Horner
    College of Health Sciences and Professions, Ohio University, W380 Grover Center, Athens, OH 45701, USA
    J Speech Lang Hear Res 54:S303-29. 2011
    ..Ethics I, they present a historical overview of the evolution of RCR in the United States then examine the evolution of human and animal experimentation from the birth of scientific medicine through World War II to the present day.
  42. ncbi Animal studies. NIH to end chimp breeding for research
    Jon Cohen
    Science 316:1265. 2007
  43. ncbi Expanding the three Rs to meet new challenges in humane animal experimentation
    Catherine A Schuppli
    Animal Welfare Program, Faculty of Agricultural Sciences and W Maurice Young Centre for Applied Ethics, University of British Columbia, 227 6356 Agriculture Road, Vancouver, BC V6T 1Z2, Canada
    Altern Lab Anim 32:525-32. 2004
    The Three Rs are the main principles used by Animal Ethics Committees in the governance of animal experimentation, but they appear not to cover some ethical issues that arise today...
  44. ncbi Is the argument from marginal cases obtuse?
    Daniel A Dombrowski
    Seattle University, Seattle, WA 98122, USA
    J Appl Philos 23:223-32. 2006
    ..The purpose of the present article is to argue that, despite Anderson's and Diamond's nuanced and perceptive treatments of the argument from marginal cases, this argument is not obtuse in either sense of the term...
  45. pmc Comparison of treatment effects between animal experiments and clinical trials: systematic review
    Pablo Perel
    Crash Trials Coordinating Centre, London School of Hygiene and Tropical Medicine, London WC1E 7HT
    BMJ 334:197. 2007
    ..To examine concordance between treatment effects in animal experiments and clinical trials. Study design Systematic review...
  46. ncbi Solutions for research chimpanzees
    Linda Brent
    Chimp Haven, Inc, 710 Spring St, 2nd Fl, Shreveport, LA, 71101, USA
    Lab Anim (NY) 33:37-43. 2004
    ..The author provides an overview of efforts to improve chimpanzee welfare, and describes a facility dedicated to providing lifelong care for these nonhuman primates following retirement from research...
  47. ncbi Ethics: views from IACUC members
    Lisa Houde
    Departement de Psychologie, Universite du Quebec a Montreal, Canada
    Altern Lab Anim 37:291-6. 2009
    ..The study suggests that IACUC members should be provided with more up-to-date information on topics such as animal ethics and animal use in research...
  48. ncbi [Animal experiments in biomedical research. An evaluation of the clinical relevance of approved animal experimental projects]
    Toni Lindl
    Institut für angewandte Zellkultur, D München
    ALTEX 22:143-51. 2005
    ..The implications of our findings may lead to demands concerning improvement of the licensing practice in Germany...
  49. ncbi The interpretation and application of the three Rs by animal ethics committee members
    Catherine A Schuppli
    The W Maurice Young Centre for Applied Ethics, The University of British Columbia, 227 6356 Agricultural Road, Vancouver, BC V6T 1Z2, Canada
    Altern Lab Anim 33:487-500. 2005
    ....
  50. pmc Translating animal research into clinical benefit
    Daniel G Hackam
    BMJ 334:163-4. 2007
  51. ncbi The refining influence of ethics committees on animal experimentation in Sweden
    Joakim Hagelin
    Department of Physiology, Division of Comparative Medicine, Uppsala University, Box 572, SE 751 23 Uppsala, Sweden
    Lab Anim 37:10-8. 2003
    ..In order to have maximal influence on the refinement of scientific protocols it is important that the scientists in the committees are continuously updated on developments in laboratory animal science...
  52. pmc Surveying the literature from animal experiments
    Roger Lemon
    BMJ 330:977-8. 2005
  53. pmc The beginning of the end for chimpanzee experiments?
    Andrew Knight
    Animal Consultants International, 91 Vanbrugh Court, Wincott St, London SE114NR, UK
    Philos Ethics Humanit Med 3:16. 2008
    ..It could even result in the first global moratorium on invasive research, for any non-human species, unless conducted in the best interests of the individual or species...
  54. ncbi Implications of experimental technique for analysis and interpretation of data from animal experiments: outliers and increased variability resulting from failure of intraperitoneal injection procedures
    R Gaines Das
    Division of Biostatistics, National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK
    Lab Anim 41:312-20. 2007
    ..p. injection failure in the analysis and interpretation of laboratory animal experiments involving this technique...
  55. pmc The ethics of animal research. Talking Point on the use of animals in scientific research
    Simon Festing
    Research Defence Society in London, UK
    EMBO Rep 8:526-30. 2007
  56. ncbi Specification of laboratory animal use in scientific articles: current low detail in the journals' instructions for authors and some proposals
    V Alfaro
    Department of Physiology, Biology, University of Barcelona, Barcelona, Spain
    Methods Find Exp Clin Pharmacol 27:495-502. 2005
    ..These proposals are classified into major and minor issues, and they are located in the corresponding parts of the article, as defined by the Introduction, Methods, Results, and Discussion (IMRAD) method...
  57. pmc Surveying the literature from animal experiments: avoidance of bias is objective of systematic reviews, not meta-analysis
    Khalid S Khan
    BMJ 331:110-1. 2005
  58. ncbi Grants proposals and animal use protocols: is the IACUC playing by the rules? Instant replay' required
    H Edwin Kennah
    Occupational and Environmental Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Lab Anim (NY) 35:16-7. 2006
  59. ncbi Grants proposals and animal use protocols: is the IACUC playing by the rules? Don't ignore the proposal
    Michael D Mann
    Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE, USA
    Lab Anim (NY) 35:17. 2006
  60. ncbi Animal health assurance
    John Donovan
    Wyeth Research, Collegeville, Pennsylvania, USA
    Curr Protoc Immunol . 2007
    ..This unit addresses all three of these health management practices. Essential in support of these practices is a diagnostic laboratory capable of testing for rodent and rabbit pathogens...
  61. ncbi Report of the 2006 RSPCA/UFAW Rodent Welfare Group meeting
    Barney Reed
    Research Animals Department, Science Group, RSPCA, Wilberforce Way, Southwater, West Sussex RH13 9RS, UK
    Lab Anim (NY) 37:216-22. 2008
    ..Topics included the housing and husbandry of mice and rats, refining the use of rodents in asthma research, good practice for the euthanasia of rodents using carbon dioxide and achieving reduction by sharing genetically modified mice...
  62. ncbi Grants proposals and animal use protocols: is the IACUC playing by the rules? Modular doesn't apply
    Michele Cunneen
    The AWEN Group Inc, Waltham, MA, USA
    Lab Anim (NY) 35:17-8. 2006
  63. ncbi Activists seek personhood for animals
    R Scott Nolen
    J Am Vet Med Assoc 223:759-60. 2003
  64. pmc Laboratory animals and the art of empathy
    D Thomas
    J Med Ethics 31:197-202. 2005
    ..Again to be consistent, we should empathise with all who may be adversely affected by our behaviour. By this yardstick, too, animal experiments fail the ethical test...
  65. ncbi Science-based assessment of animal welfare: laboratory animals
    V Baumans
    Division of Laboratory Animal Science, Utrecht University, P O Box 80 166, 3508 TD Utrecht, the Netherlands Karolinska Institute, 17177 Stockholm, Sweden
    Rev Sci Tech 24:503-13. 2005
    ..In this paper, attention is paid to the assessment of welfare, environmental factors affecting welfare, legislative requirements and future trends such as the production and use of genetically modified animals...
  66. ncbi [Animal experiments recommended by the Japanese Pharmacological Society (evaluation and decrease of pain): introduction and new guidelines for animal experiments for the Japanese Pharmacological Society]
    Yasuo Ohno
    Nihon Yakurigaku Zasshi 129:5-9. 2007
  67. ncbi [Inspection of laboratory animal facilities]
    Tsutomu Miki Kurosawa
    Nihon Yakurigaku Zasshi 129:31-4. 2007
  68. ncbi Animal welfare, human health
    Neville Goodman
    Southmead Hospital, Bristol
    Br J Hosp Med (Lond) 66:593. 2005
  69. ncbi [Importance of research on alternatives to animal experiments in pharmaceutical sciences]
    Yasuo Ohno
    National Institute of Health Sciences, Setagaya Ku, Tokyo, Japan
    Yakugaku Zasshi 128:735-40. 2008
    ..Education on proper conduct of animal experiments (3Rs, methods to evaluate and decrease distress and pain, and methods of euthanasia) was not conducted in many institutes. Further improvement seems necessary...
  70. ncbi [New guidelines and standards in revised Animal Rights Act]
    Shuji Kurio
    Nihon Seirigaku Zasshi 68:400-3. 2006
  71. ncbi Protocol audits for post-approval monitoring of animal use protocols
    Jamie F Smelser
    Animal Welfare Program, University of California, San Diego, 9500 Gillman Dr, La Jolla, CA 92093, USA
    Lab Anim (NY) 34:23-7. 2005
    ..This program, as well as the protocol audit form they provide, can be used by institutions to initiate, enhance, or evaluate post-approval monitoring programs...
  72. ncbi [An essay on the topicality and problem complex. Ethics of the Reverence for Life]
    Judith Benz-Schwarzburg
    Interfakultares Zentrum fur Ethik in den Wissenschaften IZEW, Universitat Tubingen, Germany
    ALTEX 25:63-6. 2008
    ..idea of the Reverence for Life obviously leads to ethical dilemmas - as for example in the case of animal experimentation. In many situations we cannot but kill or harm, even if we don't want to, and must live at the cost of ..
  73. ncbi Grants proposals and animal use protocols: is the IACUC playing by the rules? A word from OLAW
    Carol Wigglesworth
    Office of Laboratory Animal Welfare, OER, OD, NIH, HHS
    Lab Anim (NY) 35:18. 2006
  74. ncbi Animal experimentation in Japan: regulatory processes and application for microbiological studies
    H Takahashi-Omoe
    Science and Technology Foresight Center, National Institute of Science and Technology Policy, Ministry of Education, Culture, Sports, Science and Technology, Japan
    Comp Immunol Microbiol Infect Dis 30:225-46. 2007
    We have conducted animal experimentation as a highly effective technique in biological studies. Also in microbiological studies, we have used experimentation to prevent and treat many infectious diseases in humans and animals...
  75. ncbi Human and animal subjects of research: the moral significance of respect versus welfare
    Rebecca L Walker
    Department of Social Medicine, University of North Carolina, CB 7240, Chapel Hill, North Carolina 27599 7240, USA
    Theor Med Bioeth 27:305-31. 2006
    ..While neither potential justification is sufficient to justify the regulatory difference as it stands, there is possible common ground between supporters of some regulatory difference and those rejecting the current difference...
  76. ncbi Making sense of multiple protocols and grant applications. Failure of compliance by confusion?
    Valerie Parkison
    Tufts NEMC, Boston, MA, USA
    Lab Anim (NY) 35:15-6. 2006
  77. ncbi Making sense of multiple protocols and grant applications. Room for improvement
    Lara A Weaver
    Division of Teaching and Research Resources, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA
    Lab Anim (NY) 35:16-7. 2006
  78. doi Collaborative studies and animal reuse: one study, two institutions
    Betsy L Bashaw
    Animal Resources Facility, Albany Medical College, Albany, NY, USA
    Lab Anim (NY) 37:61-2. 2008
  79. ncbi Report of the Working Group on Animal Distress in the Laboratory
    Marilyn Brown
    Charles River Laboratories Foundation, 251 Ballardvale Street, Wilmington, MA 01887, USA
    Lab Anim (NY) 35:26-30. 2006
    ....
  80. ncbi [Developments in the area of animal experiments in biomedical research]
    C F M Hendriksen
    Nederlands Vaccin Instituut NVI en Nationaal Centrum Alternatieven voor dierproeven NCA, Universiteit Utrecht, Bilt hoven
    Ned Tijdschr Geneeskd 150:2857-62. 2006
    ..The point of departure in existing legislation on animal experimentation is the principle of 'responsible use'...
  81. ncbi [Inspection of laboratory animal breeding and husbandry/experiments on animals, examples]
    H Ratsch
    Landesamt für Gesundheit und Soziales, Berlin
    Dtsch Tierarztl Wochenschr 115:143-9. 2008
    ..If in-house supervision works well, the State's role in regulating animal experiments can be reduced...
  82. doi Collaborative studies and animal reuse: the other IACUC should decide
    Debra L Hickman
    VA Medical Center, Portland, OR, USA
    Lab Anim (NY) 37:62-3. 2008
  83. doi Collaborative studies and animal reuse: a word from OLAW and USDA
    Patricia Brown
    OLAW, OER, OD, NIH, HHS, USA
    Lab Anim (NY) 37:63. 2008
  84. doi Collaborative studies and animal reuse: inter-related, not just related
    Kathryn Nepote
    Maryland Department of Agriculture, Animal Health Diagnostic Laboratory, College Park, MD, USA
    Lab Anim (NY) 37:62. 2008
  85. ncbi An analysis of the Home Office Statistics of Scientific Procedures on Living Animals, Great Britain 2004
    Michelle Hudson
    FRAME, Nottingham, NG1 4EE, UK
    Altern Lab Anim 34:85-103. 2006
    ..The use of non-human primates and dogs is also discussed. The implications of these latest statistics are considered with reference to the implementation of the Three Rs and their consequences for animal welfare...
  86. ncbi Establishing a culture of care, conscience, and responsibility: addressing the improvement of scientific discovery and animal welfare through science-based performance standards
    H J Klein
    Department of Laboratory Animal Resources, Merck Research Laboratories, Rahway, NJ, USA
    ILAR J 48:3-11. 2007
    ....
  87. ncbi Lack of progress with the replacement of animal models in medical research
    Cliff Goodman
    Altern Lab Anim 34:127. 2006
  88. ncbi Punctual professor using passé procedures. Answer unclear
    Alan L Rothman
    IACUC Member, University of Massachusetts Medical School, Worcester, MA, USA
    Lab Anim (NY) 35:17-8. 2006
  89. ncbi Punctual professor using passé procedures. Cut the funds
    William Allen Hill
    Department of Comparative Medicine, University of Tennessee Health Science Center, Memphis, TN, USA
    Lab Anim (NY) 35:18. 2006
  90. ncbi Of mice + medicine
    Howard Bell
    Minn Med 90:30-5. 2007
  91. ncbi Modifications to husbandry and housing conditions of laboratory rodents for improved well-being
    Abigail L Smith
    School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA
    ILAR J 46:140-7. 2005
    ..Also suggested are possible inexpensive and effective enrichment schemes for laboratory mice that might include reducing the cage floor space per mouse combined with providing nesting material...
  92. ncbi Scientific procedures on living animals in Great Britain in 2003: the facts, figures and consequences
    Michelle Hudson
    FRAME, Russell and Burch House, 96 98 North Sherwood Street, Nottingham NG1 4EE, UK
    Altern Lab Anim 32:473-85. 2004
    ..The implications of these latest statistics are discussed with reference to key areas of interest and to the impact of existing regulations and pending legislative reforms...
  93. ncbi Britain seeks compromise on animal research
    Laura Nelson
    Nature 428:882. 2004
  94. ncbi Retiring to a chimp paradise
    Bridget M Kuehn
    J Am Vet Med Assoc 222:565-6. 2003
  95. ncbi Sparing animals and progressing in science
    Amalia Guaitani
    Trends Pharmacol Sci 24:616-7. 2003
  96. ncbi Using grounded theory to examine people's attitudes toward how animals are used
    Sarah Knight
    University of Portsmouth, Department of Psychology, King Henry Building, King Henry Stree, Portsmouth, UK PO1 2DY
    Soc Anim 11:307-27. 2003
    ..This paper discusses how such views may be justified and maintained...
  97. ncbi Animal experimentation as perceived by the citizens of Britain and France
    Michael Balls
    Altern Lab Anim 31:83-4. 2003
  98. ncbi [Developments in the area of animal experiments in biomedical research]
    J C Molenaar
    Ned Tijdschr Geneeskd 151:565; author reply 565. 2007
  99. ncbi Clinical blood draws: when do they require IACUC approval?
    Stacy Pritt
    Animal Resources Facility, Joslin Diabetes Center, Boston, MA, USA
    Lab Anim (NY) 33:17-21. 2004
  100. ncbi [Whereabouts of surplus and surviving laboratory animals]
    Dorothea Doehring
    Institut fuer Tierschutz, Verhaltenskunde und Tierhygiene der Tieraerztlichen Fakultaet der Ludwig Maximilians Universitaet, D Muenchen
    ALTEX 22:7-11. 2005
    ..Using such an organisation, the re-homing process is to a great extend safe and anonymous for the research institution. Many institutions already made very good experiences in the cooperation with welfare organisations...
  101. ncbi The impact of the introduction of the ethical review process for research using animals in the UK: implementation of policy
    Iain F H Purchase
    Institute of Medicine, Law and Bioethics and School of Biological Sciences, University of Manchester, UK
    Lab Anim 36:68-85. 2002
    ..A smaller proportion of respondents believed that the ERP has had a beneficial impact on animal work and training. Nearly all the respondents viewed animal care and accommodation as good or excellent...

Research Grants75

  1. Effects of Testosterone and Genetic Factors on Psychological and Motor Function i
    NICOLE RENEE TARTAGLIA; Fiscal Year: 2013
    ....
  2. Physiology of Hypothalamic Neurosteroidal Progesterone
    Paul E Micevych; Fiscal Year: 2013
    ..This type of infertility exhibits excess estrogen production without ovulation that can lead to polycystic ovary syndrome, irregular vaginal bleeding, metabolic abnormalities as well as endometrial polyps, hyperplasia, and even cancer. ..
  3. Climate Change and Adverse Birth Outcomes: Assessing the Vulnerability of Pregnan
    Shao Lin; Fiscal Year: 2013
    ..The multidisciplinary research team has a unique opportunity to use the data already collected and geo-coded through the NBDPS and other ongoing projects, which ensures the project is feasible and sustainable. ..
  4. Gross Hall Animal Resource Center
    Susan V Bryant; Fiscal Year: 2010
    ....
  5. Regional Biocontainment Laboratory
    Charles Bailey; Fiscal Year: 2007
    ..The Provost and Chief Financial Officer have committed the University to pay these costs as appropriate should they exceed the balance of the start-up contingency fund. ..
  6. Protein Phosphatase Regulation of the Principal Renal Sodium Transporter NHE3
    Ion Alexandru Bobulescu; Fiscal Year: 2013
    ....
  7. Roles of Gs Alpha and interaction with Wnt signaling in regulation of adipocyte d
    Partha S Sinha; Fiscal Year: 2011
    ..PUBLIC HEALTH RELEVANCE: This study focuses on mechanisms underlying how fat cells and bone cells develop from the bone marrow. This may help improve understanding and treatment of diseases such as obesity and osteoporosis. ..
  8. Mechanisms of Lipid-Induced Hepatic Insulin Resistance
    Gerald I Shulman; Fiscal Year: 2013
    ....
  9. MULTIDISCIPLINARY TRAINING IN PULMONARY RESEARCH
    MARK WALTER FRAMPTON; Fiscal Year: 2013
    ..by didactic courses, seminars, conferences, journal clubs, and instruction in research ethics, human and animal experimentation, and grant writing...
  10. REGULATION OF STROMAL WOUND HEALING BY GROWTH FACTORS
    GREGORY SCOTT SCHULTZ; Fiscal Year: 2012
    ....
  11. VCU Building Interdisciplinary Research Careers in Women's Health
    Jerome F Strauss; Fiscal Year: 2011
    ....
  12. Improving Air Quality for Laboratory Animal Research
    Sharron S Quisenberry; Fiscal Year: 2010
    ..A Project Liaison Officer will assist with communications and coordination among the key scientists and other Key Personnel. ..
  13. Mechanisms of Hormonal Regulation of the Sodium Chloride Cotransporter
    Robert S Hoover; Fiscal Year: 2013
    ..Mammalian cell culture, isolated tubule microperfusion and whole animal experimentation will be utilized to examine effects at the cellular/molecular, tubular and organismal level...
  14. In vivo Studies of Creatine Kinase Kinetics by 31P Magnetization Transfer MRS
    Adil Bashir; Fiscal Year: 2013
    ..The proposed project aims to develop new methodology to measure and understand energy disorders in cardiovascular disease and the techniques developed will be critically useful to advance basic research and medical care. ..
  15. Interaction of thrombospondin-1 with alpha9beta1 integrin in glioma angiogenesis
    Cezary Marcinkiewicz; Fiscal Year: 2012
    ..Investigation of this receptor may be beneficial for cancer as well as for cardiovascular disease having patients, because regulation of vascularization process is important in these pathologies. ..
  16. Functional analysis of Chk2 in DNA damage response
    Jun Hyun Kim; Fiscal Year: 2013
    ....
  17. Novel Therapies and Biomarkers for the Mucopolysaccharidoses
    CALOGERA MARIA SIMONARO; Fiscal Year: 2013
    ..Each of the four molecules to be studied has already shown efficacy in animal models of arthritis, and one (Remicade") is clinically available. ..
  18. Inflammasome Activation in Complex Regional Pain Syndrome
    Wade S Kingery; Fiscal Year: 2013
    ....
  19. Mathematical Modeling of Inflammation in ARDS
    Yoram Vodovotz; Fiscal Year: 2010
    ..End of Abstract) ..
  20. Mathematical Modeling of Inflammation in ARDS
    Gary F Nieman; Fiscal Year: 2010
    ..End of Abstract) ..
  21. Molecular and Cellular Determinants of the Exercise Pressor Reflex in CHF
    Irving H Zucker; Fiscal Year: 2013
    ..Furthermore, w believe that these data will uncover new targets for therapy in CHF. ..
  22. A short course: An organ systems approach to target the Metabolic syndrome
    Owen P McGuinness; Fiscal Year: 2012
    ..The benefit to human disease is that these trainees will now be equipped with the tools necessary to fill a void in our training programs. ..
  23. WHOLE SLIDE IMAGING SYSTEM FOR TRANSLATIONAL NEUROSCIENCE
    Jin Moo Lee; Fiscal Year: 2010
    ..Data sharing provides great dividends by facilitating comparisons between disease models, and allowing new research findings on existing data without having to perform additional animal experiments. ..
  24. Aerobic Exercise, Neurotrophins, and fMRI of Hippocampal Function and Structure
    Karin Schon; Fiscal Year: 2011
    ..This set of studies aims to examine the relationship between aging, exercise, and the brain in healthy young and older individuals. ..
  25. Epidemiology & epigenetics: Maternal diet, DNA methylation, & offspring adiposity
    Matthew W Gillman; Fiscal Year: 2010
    ..Second is public health importance-- optimizing maternal diet in early pregnancy could improve the health of the next generation. ..
  26. Integrative Neural Systems Underlying Vital Aerodigestive Tract Functions
    Joanne Robbins; Fiscal Year: 2010
    ..The conference will provide a unique forum for established scholars and their doctoral students and fellows from multiple inter-related disciplines to interact, share ideas, present, collaborate and make important contributions. ..
  27. Aging Auditory System: Presbycusis and Its Neural Bases
    Robert D Frisina; Fiscal Year: 2013
    ..SPECIFIC AIM 3: Investigate the Neural Bases and Possible Reversibility of the Accelerated Age-Related Hearing Loss Associated with Medical Conditions: Ear and Brain Analyses. ..
  28. College of Medicine Phoenix Campus Vivarium Phase I Construction
    William M Crist; Fiscal Year: 2010
    ..The best and only way to assure optimal standards of experimental animal care required for our PHS-supported research efforts is to construct this dedicated laboratory animal vivarium serving the Phoenix Biomedical Campus. ..
  29. NORADRENERGIC SYSTEM IN DEPRESSION
    GREGORY ALLEN ORDWAY; Fiscal Year: 2012
    ..Understanding the molecular pathology of this disorder holds the promise of identifying new biological targets for the development of improved treatments. ..
  30. In Utero Exposure to Bisphenol A: Effects on the Fetal Epigenome
    DANA DOLINOY; Fiscal Year: 2013
    ....
  31. Body Burden of PAHs and Cardiovascular Disease in the United States
    JOHN DAVIS CLARK; Fiscal Year: 2010
    ..Results of this proposed study can be used to influence policy decisions and resource allocation for the prevention of cardiovascular disease. ..
  32. Endothelial Injury in Endotoxin-Induced Acute Renal Failure
    Patrick N Cunningham; Fiscal Year: 2013
    ....
  33. Astrocyte Control of Toxin-Mediated Neuron Death: Role of the Gamma-Glutamyl Path
    George I Henderson; Fiscal Year: 2010
    ..We will determine how the toxins damage it (to prevent this from happening), and how this system is normally controlled. ..
  34. High Sensitivity Mobile PET for Brain Imaging and Proton Therapy Monitoring
    Georges El Fakhri; Fiscal Year: 2010
    ....
  35. Aerobic Exercise, Neurotrophins, and fMRI of Hippocampal Function and Structure
    Karin Schon; Fiscal Year: 2013
    ..Regular moderate intensity aerobic exercise may have neuroprotective effects throughout the lifespan. ..
  36. Biocompatibility of Implantable Renal Replacement Devices
    Shuvo Roy; Fiscal Year: 2013
    ....
  37. Mechamism of Activation of Oxidative Metabolism in vivo During Exercise
    JESSICA ROSE SPIRES; Fiscal Year: 2012
    ....
  38. HORMONAL REGULATION OF BLOOD PRESSURE
    Michal Laniado Schwartzman; Fiscal Year: 2013
    ..ular tone, in the pathophysiology of hypertension and cardiovascular disease. ..
  39. Engineering of Human Corneal Endothelial Grafts
    Ying Ting Zhu; Fiscal Year: 2012
    ..Furthermore, the said technology may also be applied to engineer other similar tissues, such as the retinal pigment epithelium, in the future. ..
  40. Mechanisms of Altered Glucose Metabolism in Sleep-Disordered Breathing
    Naresh Punjabi; Fiscal Year: 2013
    ....
  41. Construction of a Dual Function Primate Facility: ABSL3 and Transplant Medicine
    Stuart M Zola; Fiscal Year: 2010
    ....
  42. Cyclotron for PET Radiopharmaceuticals
    Jogeshwar Mukherjee; Fiscal Year: 2013
    ....
  43. CENTRAL THALAMIC DEEP BRAIN STIMULATION MODELS
    Nicholas D Schiff; Fiscal Year: 2013
    ..The studies proposed here will help to advance the necessary knowledge to advance and further develop a novel application of electrical brain stimulation aimed at improving the lives of patients suffering with these lifelong challenges. ..
  44. Determinants of Nicotine Reinforcement Thresholds and Demand Elasticity in Rats
    Mark G LeSage; Fiscal Year: 2013
    ..As such, the present study could contribute to the scientific basis for evaluation of reduced nicotine tobacco products and their clinical and public health consequences. ..
  45. Sensitivity to smoking reinforcement in women: menstrual cycle effects
    Elizabeth Van Voorhees; Fiscal Year: 2012
    ....
  46. Role of C/EBPbeta in mechanical regulation of MSC potential
    Maya Styner; Fiscal Year: 2013
    ....
  47. Integrative Lipid Metabolism, Inflammation, and Chronic Diseases
    John S Parks; Fiscal Year: 2013
    ..Training will involve an integrated, multidisciplinary approach that uses molecular, cellular, and whole animal experimentation. Training for students will include rigorous didactic courses, seminars, journal clubs, Program Project ..
  48. One Health Innovation Fellowships for Zoonotic Disease Research In Mongolia
    GREGORY CHARLES GRAY; Fiscal Year: 2013
    ..abstract_text> ..
  49. Gene Expression, Compensation Mechanisms, and Successful Cognitive Aging
    CARL WAYNE COTMAN; Fiscal Year: 2013
    ..Accordingly, these studies will help provide a rational for including exercise as a formula to promote successful cognitive health during aging. ..
  50. Age Dependent Mechanical Ventilator-Induced Inflammation: Modeling &Experiments
    ANGELA MARIE REYNOLDS; Fiscal Year: 2013
    ....
  51. Genesis of Esophageal Pain: Longitudinal Muscle Spasm and Wall Ischemia
    Ravinder K Mittal; Fiscal Year: 2013
    ..With the better understanding of pathogenesis of pain, we hope more effective strategies to treat esophageal pain will be forthcoming. ..
  52. Pre- and peri-natal predictors of childhood obesity
    Matthew W Gillman; Fiscal Year: 2013
    ..The results of this research will lead to new scientific knowledge about the drivers of growth and adiposity in childhood and may very well lead to new avenues for prevention of obesity, diabetes, and cardiovascular disease. ..
  53. Dissecting expression divergence in developmental networks across Drosophilids
    ZEBA BATOOL WUNDERLICH; Fiscal Year: 2013
    ..The department and university has a number of faculty members with interests that overlap with mine and also provides the animal husbandry, microscopy, computational and administrative resources that will enable this project. ..
  54. Nanotechnology enabled desktop image-guided microbeam radiation therapy system
    OTTO Z contact ZHOU; Fiscal Year: 2010
    ..If human patients response to MRT in similar ways as reported in numerous MRT animal studies, MRT will literally revolutionize cancer treatment. ..
  55. Force Clamp Systems for Evaluation of Mechanotransduction
    BETH L PRUITT; Fiscal Year: 2013
    ....
  56. Effector and regulatory T cell responses and protection from clinical malaria
    Margaret E Feeney; Fiscal Year: 2013
    ..but not liver-stage malaria, will be compared to children who do not receive chemoprevention, and these immune parameters will be correlated with prospective protection from clinical malaria following cessation of chemoprevention ..
  57. An XFM Interventional Guidance System for Cardiac Resynchronization Therapy
    Reza Nezafat; Fiscal Year: 2012
    ....
  58. Nicotine delivery to rodents with lung alveolar region-targeted aerosol tech
    Xinmin Simon Xie; Fiscal Year: 2011
    ..Furthermore, this method will serve as a platform to develop more effective and safer medications for smoking cessation and treatment of tobacco-related diseases. ..
  59. An Animal Biosafety Level 3 Laboratory for Stony Brook University
    Samuel L Stanley; Fiscal Year: 2010
    ....
  60. Inhibition of Lung Carcinogenesis by Tea Polyphenols and Atorvastatin
    Chung S Yang; Fiscal Year: 2012
    ..The possible use of the combination of tea polyphenols and Lipitor for lung cancer prevention is an attractive strategy and could have a large impact in public health. ..
  61. Toll-like receptors and intestinal inflammation
    Charalabos Pothoulakis; Fiscal Year: 2010
    ..Our proposed studies will provide significant information relevant to the pathogenesis of colonic inflammation, including IBD. ..
  62. Self Organized Criticality as a new paradigm of sleep regulation
    PLAMEN CHRISTOV IVANOV; Fiscal Year: 2013
    ....
  63. Bladder Voiding via Pudendal Nerve Block
    KENNETH GUSTAFSON; Fiscal Year: 2009
    ..In addition, the substantial potential future clinical impact from HF nerve block to a number of other clinical applications, such as chronic pain, muscle spasticity, etc. increases the value of this work. ..
  64. Improving Outcomes in Hydrocephalus: Bridging the Gap between Basic Science and C
    James McAllister; Fiscal Year: 2009
    ..We expect that this conference will create a substantial increase in the quality and quantity of hydrocephalus research similar to the advances gained from the previous workshop. ..
  65. Exchangeable Heart Valve for Tissue Engineering Applications
    Ivan Vesely; Fiscal Year: 2007
    ..VXI will thus continue to advance the field of heart valve technologies into new areas where innovative solutions for patients with heart valve disease are needed. [unreadable] [unreadable] [unreadable]..
  66. In Vivo Optical Imaging Scanner for Small Animal Research
    STUART BERR; Fiscal Year: 2009
    ....
  67. EXTRAMURAL RESEARCH FACILITIES IMPROVEMENT PROGRAM
    John Blake; Fiscal Year: 2005
    ..We are recognizably weak in PHS funding but we have confidence in our new scientists and we are motivated to provide the necessary environment for them to succeed. ..
  68. MRI-Guided Angioplasty of Renal Artery Stenosis
    Reed Omary; Fiscal Year: 2005
    ..MRI guidance will also avoid the ionizing radiation exposure of x-rays and the potential kidney toxicity of iodinated contrast agents. ..
  69. Cardiovascular Inflammation Function Imaging by Photoacoustics using Gold Nanorod
    Kang Kim; Fiscal Year: 2010
    ..This method also can be rapidly translated into clinical practice since it is based upon novel processing of ultrasound data that can be obtained with commercially available scanners. ..
  70. Adenosine and Nitric Oxide Deficiency
    Italo Biaggioni; Fiscal Year: 2004
    ....
  71. MODEL OF DYSRHYTHMIAS AFTER CONGENITAL HEART SURGERY
    Arthur Garson; Fiscal Year: 1991
    ....
  72. MECHANISMS OF PULMONARY FIBROSIS CAUSED BY SILICA
    Gerald Davis; Fiscal Year: 2003
    ..And other interstitial lung diseases where the cause is not known and treatment is not effective. ..
  73. ANIMAL FACILITY IMPROVEMENT
    TERESA SYLVINA; Fiscal Year: 1992
    ..5. Meet NIH and USDA standards for housing cats and monkeys and enhance their psychological well-being by replacing existing caging with new stainless steel cages. ..
  74. NEURONAL BASIS OF VISUAL PERCEPTION IN EYE MOVEMENTS
    Hitoshi Sato; Fiscal Year: 1991
    ....
  75. DEVELOPING AND IMPROVING INSTITUTIONAL ANIMAL RESOURCES
    Patrick Manning; Fiscal Year: 1992
    ..The program is part of a centralized program of laboratory animal care on the Twin Cities Campus...