Top Publications

  1. ncbi From pixels to picograms: a beginners' guide to genome quantification by Feulgen image analysis densitometry
    David C Hardie
    Department of Zoology, University of Guelph, Guelph, Ontario, Canada
    J Histochem Cytochem 50:735-49. 2002
  2. ncbi The effects of radiation dose and CT manufacturer on measurements of lung densitometry
    Ren Yuan
    Department of Radiology, Vancouver General Hospital, 855 West Twelfth Ave, Room 3350 JPN, Vancouver, BC, Canada
    Chest 132:617-23. 2007
  3. ncbi Quantifying Western blots: pitfalls of densitometry
    Max Gassmann
    Institute of Veterinary Physiology, Vetsuisse Faculty University of Zürich and Zürich Center for Integrative Human Physiology, University of Zurich, Switzerland
    Electrophoresis 30:1845-55. 2009
  4. pmc Analysis of nuclear DNA content in Capsicum (Solanaceae) by flow cytometry and Feulgen densitometry
    Eduardo A Moscone
    Instituto Multidisciplinario de Biología Vegetal IMBIV, Casilla de Correo 495, 5000 Cordoba, Argentina
    Ann Bot 92:21-9. 2003
  5. ncbi Identifying bone-mass-related risk factors for fracture to guide bone densitometry measurements: a systematic review of the literature
    M Espallargues
    Catalan Agency for Health Technology Assessment and Research, Barcelona, Spain
    Osteoporos Int 12:811-22. 2001
  6. ncbi Application of TLC-densitometry, first-derivative UV-spectrophotometry and ratio derivative spectrophotometry for the determination of dorzolamide hydrochloride and timolol maleate
    Lories I Bebawy
    National Organization for Drug Control and Research, 6 Hussen Kamal el Deen, Ben el Sariat, Dokki, Giza, Egypt
    J Pharm Biomed Anal 27:737-46. 2002
  7. ncbi Blood volume measurement: The comparison of pulse dye densitometry and Dill and Costill's methods
    Eric Belin de Chantemele
    Laboratoire de Physiologie, UMR CNRS 6188, Faculté de Médecine d Angers, Rue Haute de Reculee, 49045 Angers Cedex, France
    Life Sci 78:1564-9. 2006
  8. pmc Enumeration of Mycobacterium avium subsp. paratuberculosis by quantitative real-time PCR, culture on solid media and optical densitometry
    Petr Kralik
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    BMC Res Notes 5:114. 2012
  9. ncbi Clinical application of autofluorescence densitometry with a scanning laser ophthalmoscope
    Tetsuju Sekiryu
    Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, Japan
    Invest Ophthalmol Vis Sci 50:2994-3002. 2009
  10. ncbi Effect of 17beta-estradiol or alendronate on the bone densitometry, bone histomorphometry and bone metabolism of ovariectomized rats
    L H da Paz
    Departamento de Reumatologia, Faculdade de Medicina, Universidade de Sao Paulo, Av Dr Arnaldo, 01246 930 São Paulo SP, Brazil
    Braz J Med Biol Res 34:1015-22. 2001

Detail Information

Publications277 found, 100 shown here

  1. ncbi From pixels to picograms: a beginners' guide to genome quantification by Feulgen image analysis densitometry
    David C Hardie
    Department of Zoology, University of Guelph, Guelph, Ontario, Canada
    J Histochem Cytochem 50:735-49. 2002
    ..In this review, we provide a practical guide to the new technique of Feulgen image analysis densitometry. The review is designed for those interested in genome size measurements but not extensively experienced in ..
  2. ncbi The effects of radiation dose and CT manufacturer on measurements of lung densitometry
    Ren Yuan
    Department of Radiology, Vancouver General Hospital, 855 West Twelfth Ave, Room 3350 JPN, Vancouver, BC, Canada
    Chest 132:617-23. 2007
    ..To evaluate the effect of radiation dose and scanner manufacturer on quantitative CT scan measurements of lung morphology in smokers...
  3. ncbi Quantifying Western blots: pitfalls of densitometry
    Max Gassmann
    Institute of Veterinary Physiology, Vetsuisse Faculty University of Zürich and Zürich Center for Integrative Human Physiology, University of Zurich, Switzerland
    Electrophoresis 30:1845-55. 2009
    Although Western blots are frequently quantified, densitometry is not documented and appears to be based merely on traditions and guesswork...
  4. pmc Analysis of nuclear DNA content in Capsicum (Solanaceae) by flow cytometry and Feulgen densitometry
    Eduardo A Moscone
    Instituto Multidisciplinario de Biología Vegetal IMBIV, Casilla de Correo 495, 5000 Cordoba, Argentina
    Ann Bot 92:21-9. 2003
    ..In addition, one sample each of C. annuum var. annuum and C. pubescens were also analysed using Feulgen densitometry (standard, Allium cepa 'Stuttgarter Riesen', 1C = 16.75 pg)...
  5. ncbi Identifying bone-mass-related risk factors for fracture to guide bone densitometry measurements: a systematic review of the literature
    M Espallargues
    Catalan Agency for Health Technology Assessment and Research, Barcelona, Spain
    Osteoporos Int 12:811-22. 2001
    Available evidence suggests that fracture prediction with bone densitometry may improve when used on people at high risk of osteoporotic fractures...
  6. ncbi Application of TLC-densitometry, first-derivative UV-spectrophotometry and ratio derivative spectrophotometry for the determination of dorzolamide hydrochloride and timolol maleate
    Lories I Bebawy
    National Organization for Drug Control and Research, 6 Hussen Kamal el Deen, Ben el Sariat, Dokki, Giza, Egypt
    J Pharm Biomed Anal 27:737-46. 2002
    ..The proposed methods were successfully applied to the determination of these compounds in synthetic mixtures and in pharmaceutical preparations. The proposed methods are simple, rapid and suitable for quality control application...
  7. ncbi Blood volume measurement: The comparison of pulse dye densitometry and Dill and Costill's methods
    Eric Belin de Chantemele
    Laboratoire de Physiologie, UMR CNRS 6188, Faculté de Médecine d Angers, Rue Haute de Reculee, 49045 Angers Cedex, France
    Life Sci 78:1564-9. 2006
    ..27). The DDG gives a good repeatability, not affected by the microgravity exposure. Thanks to its capacity to measure accurately the BV within 7-10 min, this device presents major advantages for clinical use and research purpose...
  8. pmc Enumeration of Mycobacterium avium subsp. paratuberculosis by quantitative real-time PCR, culture on solid media and optical densitometry
    Petr Kralik
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    BMC Res Notes 5:114. 2012
    ..McFarland turbidity standards were also compared with F57qPCR and culture, due to its frequent inclusion and use in MAP studies...
  9. ncbi Clinical application of autofluorescence densitometry with a scanning laser ophthalmoscope
    Tetsuju Sekiryu
    Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, Japan
    Invest Ophthalmol Vis Sci 50:2994-3002. 2009
    ..This study reports a clinical application of FAF in measuring photopigments by scanning laser ophthalmoscopy (SLO)...
  10. ncbi Effect of 17beta-estradiol or alendronate on the bone densitometry, bone histomorphometry and bone metabolism of ovariectomized rats
    L H da Paz
    Departamento de Reumatologia, Faculdade de Medicina, Universidade de Sao Paulo, Av Dr Arnaldo, 01246 930 São Paulo SP, Brazil
    Braz J Med Biol Res 34:1015-22. 2001
    ..1 mg/kg for 6 weeks (OVX-A, N = 8). Histomorphometry, densitometry, osteocalcin and deoxypyridinoline measurements were applied to all groups...
  11. pmc The short-term effect of atorvastatin on carotid plaque morphology assessed by computer-assisted gray-scale densitometry: a pilot study
    David Della-Morte
    Department of Neurology, Leonard M Miller School of Medicine, University of Miami, Miami, FL, USA
    Neurol Res 33:991-4. 2011
    ..Computer assisted gray-scale densitometry (GSD) index was calculated at baseline and 30 days after treatment from the normalized plaque images...
  12. ncbi Use of bone densitometry by Ontario family physicians
    R Ridout
    Department of Medicine, Sunnybrook and Women s Health Sciences Centre, University of Toronto, Canada
    Osteoporos Int 11:393-9. 2000
    ..The questionnaire examined current use of bone densitometry, focusing on reasons for its use, factors that limit use, and features of the report that are helpful to the ..
  13. ncbi Quality and performance measures in bone densitometry. Part 2: fracture risk
    C C Gluer
    Medizinische Physik, Klinik für Diagnostische Radiologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Kiel, Germany
    Osteoporos Int 17:1449-58. 2006
    This is part 2 of a core chapter of the forthcoming Report on Bone Densitometry commissioned by the International Commission on Radiation Units (ICRU)...
  14. pmc Quantitative western immunoblotting analysis in survey of human immunodeficiency virus-seropositive patients
    D G Schiavini
    Laboratory of Virology, Centre Hospitalier Universitaire Purpan, Toulouse, France
    J Clin Microbiol 27:2062-6. 1989
    ..The results are expressed as integrals. This technique confirms the decrease in p24 and p17 antibodies as the criterion giving the earliest prediction of the progression to acquired immunodeficiency syndrome...
  15. ncbi A novel technique to assess chromatin texture using pixel optical densitometry in oral squamous cell carcinoma
    Srikant Natarajan
    Department of Oral Pathology, Manipal College of Dental Sciences, Mangalore 575001, Karnataka, India nskant rediffmail com
    Microsc Res Tech 75:1119-23. 2012
    ..This study was aimed to assess and correlate the progressive changes in chromatin texture from normal to varying grades of premalignancies to malignancy of the oral cavity...
  16. pmc Elevated homocysteine and carotid plaque area and densitometry in the Northern Manhattan Study
    Sara Alsulaimani
    Department of Neurology, Miller School of Medicine, University of Miami, Clinical Research Bldg 1120, NW 14 St, Miami, FL 33136, USA
    Stroke 44:457-61. 2013
    ..We examined the association between tHcy and carotid plaque burden and morphology in a multiethnic cohort...
  17. ncbi Estimation of adenosine and its major metabolites in brain tissues of rats using high-performance thin-layer chromatography-densitometry
    Kiran Kumar Akula
    Pharmacology Division, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
    J Chromatogr A 1209:230-7. 2008
    A new, rapid and sensitive high-performance thin-layer chromatographic (HPTLC) method with densitometry was developed and validated for the concomitant estimation of purines like adenosine (Ade) and its major metabolites, inosine (Ino) ..
  18. ncbi Wavefront-optimized excimer laser in situ keratomileusis for myopia and myopic astigmatism: refractive outcomes and corneal densitometry
    Usama Fares
    Division of Ophthalmology and Visual Sciences, University of Nottingham, Nottingham, United Kingdom
    J Cataract Refract Surg 38:2131-8. 2012
    To determine the refractive outcomes of wavefront-optimized laser in situ keratomileusis (LASIK) treatments, in particular to measure corneal densitometry after LASIK using the densitometry function of the Pentacam Scheimpflug system.
  19. pmc Wood densitometry in 17th and 18th century Dutch, German, Austrian and French violins, compared to classical Cremonese and modern violins
    Berend C Stoel
    Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands
    PLoS ONE 7:e46629. 2012
    ..conjecture is true, we analyzed 17 modern and classical Dutch, German, Austrian and French violins by wood densitometry using computed tomography and correlated these results with our previous study of modern and Cremonese violins; ..
  20. ncbi Effects of low-level laser therapy (LLLT) on bone repair in rats: optical densitometry analysis
    Danillo Barbosa
    Instituto de Engenharia Biomedica, Universidade Camilo Castelo Branco, Unicastelo, Rodovia BR 116, 12247 004, Sao Jose dos Campos, Sao Paulo, Brazil
    Lasers Med Sci 28:651-6. 2013 was to evaluate the process of bone repair in rats submitted to low-level laser therapy using optical densitometry. A total of 45 rats which underwent femoral osteotomy were randomly distributed into three groups: control (..
  21. ncbi Validation of a high-performance thin-layer chromatography/densitometry method for the quantitative determination of glucosamine in a herbal dietary supplement
    Virginie Esters
    Laboratory of Pharmacognosy, Department of Pharmacy, University of Liege, CHU, B36, Avenue de l Hopital 1, B 4000 Liege, Belgium
    J Chromatogr A 1112:156-64. 2006
    ..9 and 8.6%. Moreover, the method was found to be accurate, as the two-sided 95% beta-expectation tolerance interval did not exceed the acceptance limits of 85 and 115% on the whole analytical range (800-1,200 ng of glucosamine)...
  22. ncbi Measurement of cardiac output by pulse dye densitometry using indocyanine green: a comparison with the thermodilution method
    T Imai
    Department of Anesthesiology, Gunma University School of Medicine, Maebashi, Japan
    Anesthesiology 87:816-22. 1997
    A new method for determining cardiac output (CO, l/min) using dye dilution combined with pulse dye densitometry (PDD), based on the principle of pulse oximetry, has been developed...
  23. ncbi Normative values for corneal densitometry analysis by Scheimpflug optical assessment
    Sorcha Ni Dhubhghaill
    Department of Ophthalmology, Antwerp University Hospital, Edegem, Belgium
    Invest Ophthalmol Vis Sci 55:162-8. 2014
    To describe the normative data for corneal Scheimpflug densitometry based on a cohort of normal participants.
  24. pmc Alveolar bone healing process in spontaneously hypertensive rats (SHR). A radiographic densitometry study
    Natalia Manrique
    Department of Pediatric and Community Dentistry, School of Dentistry of Aracatuba, Univ Estadual Paulista, Aracatuba, SP, Brazil
    J Appl Oral Sci 20:222-7. 2012
    ..If undiagnosed or untreated, this pathology represents a systemic risk factor and offers unfavorable conditions for dental treatments, especially those requiring bone healing...
  25. ncbi Measuring circulating blood volume in newborn infants using pulse dye densitometry and indocyanine green
    Narendra Aladangady
    Department of Child Health, Homerton University Hospital Bart s and the London School of Medicine and Dentistry, London, UK
    Paediatr Anaesth 18:865-71. 2008
    ..Circulating blood volume (BV) is an important, but often unconsidered, variable in newborn infants undergoing intensive care. The data on validation and repeatability of BV measurement are limited...
  26. ncbi Correlation of body growth and bone mineral density measured by ultrasound densitometry of the calcaneus in children and adolescents
    Takahiko Nohara
    Health Administration Center Izumo, Shimane University, Izumo, Japan
    Tohoku J Exp Med 219:63-9. 2009
    ..Boys and girls show a similar growth pattern in body height and weight before peak development; however, the physical growth of boys eventually exceeds that of girls...
  27. ncbi Simultaneous identification and quantitative determination of selected aminoglycoside antibiotics by thin-layer chromatography and densitometry
    Urszula Hubicka
    Collegium Medicum of Jagiellonian University, Department of Inorganic and Analytical Chemistry, Medyczna 9, 30 688 Krakow, Poland
    J AOAC Int 92:1068-75. 2009
    ..65 microg for gentamicin, and a wide linearity range 0.75-6.25 microg/spot for amikacin and netilmicin and 1.5-12.50 microg/spot for other antibiotics. The precision of the determination was very good; RSD varied in the range 0.3-0.6%...
  28. pmc Prevalence and risk factors of discordance in diagnosis of osteoporosis using spine and hip bone densitometry
    Abdellah El Maghraoui
    Ann Rheum Dis 66:271-2. 2007
  29. ncbi Fast determination of colchicine by TLC-densitometry from pharmaceuticals and vegetal extracts
    E Bodoki
    Faculty of Pharmacy, Iuliu Hatieganu University of Medicine and Pharmacy, Emil Isac St 13, RO 400023 Cluj Napoca, Romania
    J Pharm Biomed Anal 37:971-7. 2005
  30. ncbi Determination of analytes in medical herbs extracts by SPE coupled with two-dimensional planar chromatography in combination with diode array scanning densitometry and HPLC-diode array detector
    Tomasz Tuzimski
    Department of Physical Chemistry, Chair of Chemistry, Faculty of Pharmacy with Medical Analytics Division, Medical University of Lublin, Lublin, Poland
    J Sep Sci 34:27-36. 2011
    ..samples spiked with pesticide at a concentration level of 10 μg/g in plant material are presented. Method validation parameters for the quantification of pesticides by the proposed HPLC-DAD after SPE method are also presented...
  31. ncbi [Bone metabolism in dialysis patient assessed by biochemical markers and densitometry]
    Jolanta Małyszko
    Klinika Nefrologii i Chorób Wewnetrznych AM w Białymstoku
    Pol Arch Med Wewn 110:967-72. 2003
    ..52, p < 0.05). On the basis of our finding we conclude that BMD depends on time of renal replacement therapy. Biochemical markers of bone metabolism poorly correlate with bone mineral density in dialyzed patients...
  32. ncbi Contrast sonography, video densitometry and intervillous blood flow: a pilot project
    W H Barth
    Vincent Memorial Hospital, Women s Care Division of the Massachusetts General Hospital, Boston, MA 02114, USA
    Placenta 27:719-26. 2006
    To examine the feasibility of constructing time-intensity (TI) curves from the intervillous space with an intravascular ultrasound contrast agent and computer assisted video densitometry.
  33. ncbi Benefits for bone from resistance exercise and nutrition in long-duration spaceflight: Evidence from biochemistry and densitometry
    Scott M Smith
    Human Adaptation and Countermeasures Division, National Aeronautics and Space Administration, Lyndon B Johnson Space Center, 2101 NASA Parkway, Houston, TX 77058, USA
    J Bone Miner Res 27:1896-906. 2012
    ..We report dietary intake, bone densitometry, and biochemical markers in 13 crewmembers on ISS missions from 2006 to 2009...
  34. ncbi Quality assessment for tramadol in pharmaceutical preparations with thin layer chromatography and densitometry
    Jan Krzek
    Jagiellonian University, Collegium Medicum, Department of Inorganic and Analytical Chemistry, 9 Medyczna Str, 30 688 Krakow, Poland
    Biomed Chromatogr 18:589-99. 2004
    ..1, v/v/v); (II) chloroform-toluene-ethanol (9:8:1, v/v/v). The UV densitometry was carried out at lambda = 270 nm...
  35. ncbi Official positions of the International Society for Clinical Densitometry
    Edward S Leib
    South Med J 97:107-10. 2004
  36. pmc Risk factors for prevalent vertebral fractures in black and white female densitometry patients
    Tamara J Vokes
    Department of Medicine, University of Chicago, Chicago, IL 606037, USA
    J Clin Densitom 10:1-9. 2007
    ..We conclude that use of corticosteroids may be associated with relatively greater vertebral fracture risk in blacks than in whites...
  37. ncbi [2008 official positions of the Brazilian Society for Clinical Densitometry--SBDens]
    Cynthia M A Brandão
    Sociedade Brasileira de Densitometria Clínica, Rua Pelotas 562, Sao Paulo SP
    Arq Bras Endocrinol Metabol 53:107-12. 2009
    With the evolution of bone densitometry, differences in technologies, acquisition techniques, reference databases, reporting methods, diagnostic criteria and terminology have developed and the International Society for Clinical ..
  38. pmc Comparison of trabecular metal cups and titanium fiber-mesh cups in primary hip arthroplasty: a randomized RSA and bone mineral densitometry study of 50 hips
    Thomas Baad-Hansen
    Department of Orthopaedic Surgery, Aarhus University Hospital, Denmark
    Acta Orthop 82:155-60. 2011
    ..In this randomized RSA trial, we compared a new acetabular cup with a surface made of tantalum trabecular metal and a cup with a titanium fiber-mesh surface...
  39. ncbi Pulse dye densitometry and indocyanine green plasma disappearance in ASA physical status I-II patients
    Marije Reekers
    Department of Anesthesiology, Leiden University Medical Centre, Leiden, The Netherlands
    Anesth Analg 110:466-72. 2010
    ..In addition, we evaluated the noninvasive measurement of ICG-PDR (transcutaneously by pulse dye densitometry [PDD] at the finger and the nose) and compared these with the simultaneously performed invasive measurements of ..
  40. ncbi Application of first-derivative, ratio derivative spectrophotometry, TLC-densitometry and spectrofluorimetry for the simultaneous determination of telmisartan and hydrochlorothiazide in pharmaceutical dosage forms and plasma
    Lories I Bebawy
    National Organization for Drug Control and Research, 6 Hussein Kamal El Deen, Ben El Saraiat, Dokki, Gizza 12311, Egypt
    Farmaco 60:859-67. 2005
    ..The proposed methods were applied successfully for the determination of the two drugs in bulk powder and in pharmaceutical formulations. The spectrofluorimetric method was utilized for the analysis of TELM in human plasma...
  41. ncbi An objective method to measure cell survival by computer-assisted image processing of numeric images of Petri dishes
    Marie Claude Biston
    Equipe d Accueil no 2941 Rayonnement Synchrotron et Recherche Médicale, Unité IRM, CHU, BP 217, F 38043 Grenoble 09, France
    Phys Med Biol 48:1551-63. 2003
    ..The large amount of data produced also gives information about cell and colony characteristics. Thus, this computer-assisted method has considerably improved the reliability of our statistical results...
  42. ncbi Blood volume measurement at the bedside using ICG pulse spectrophotometry
    M Haruna
    Division of Surgical Intensive Care, National Cardiovascular Center, Suita, Osaka, Japan
    Anesthesiology 89:1322-8. 1998
    ..In 10-30% of tests the method failed because of motion distortion of the record during the 10-min data collection period or because of insufficient pulse amplitude in the test tissue...
  43. ncbi Exploring the role of CT densitometry: a randomised study of augmentation therapy in alpha1-antitrypsin deficiency
    A Dirksen
    Gentofte Hospital, Copenhagen University, Hellerup, Denmark
    Eur Respir J 33:1345-53. 2009
    ..and Computed Tomography scan as Lung End-points (EXACTLE) trial explored the use of computed tomography (CT) densitometry and exacerbations for the assessment of the therapeutic effect of augmentation therapy in subjects with alpha(1)..
  44. ncbi Radiopacity evaluation of root-end filling materials by digitization of images
    Mario Tanomaru-Filho
    Department of Restorative Dentistry, Dental School of Araraquara, Sao Paulo State University, Araraquara, SP, Brazil
    J Appl Oral Sci 16:376-9. 2008
    ..05), while white/grey MTA and Super EBA presented the lowest radiopacity values (p<0.05). The tested root-end filling materials presented different radiopacities, white/grey MTA and Super EBA being the least radiopaque materials...
  45. pmc Therapeutic efficacy of α-1 antitrypsin augmentation therapy on the loss of lung tissue: an integrated analysis of 2 randomised clinical trials using computed tomography densitometry
    Robert A Stockley
    Lung Investigation Unit, University Hospitals of Birmingham, Edgbaston, Birmingham B15 2TH, UK
    Respir Res 11:136. 2010
    Two randomised, double-blind, placebo-controlled trials have investigated the efficacy of IV alpha-1 antitrypsin (AAT) augmentation therapy on emphysema progression using CT densitometry.
  46. ncbi Rat lumbar vertebrae bone densitometry using multidetector CT
    Yi Xiang J Wang
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, People s Republic of China
    Eur Radiol 19:882-90. 2009
    ..The following comparisons were carried out: 2.5-mm MDCT densitometry versus 0.625-mm MDCT densitometry; 0...
  47. ncbi Preclinical thalassemic cardiopathy: a study by acoustic densitometry
    Roberto Di Paola
    Cardiology Unit, Garibaldi Hospital, Catania, Italy
    Ital Heart J 4:413-8. 2003
    The cardiac function in thalassemia major has never been studied at ultrasonic backscatter techniques. We assessed the utility of acoustic densitometry in thalassemic patients without clinical or echocardiographic signs of heart failure.
  48. ncbi Fetal programming of body dimensions and percentage body fat measured in prepubertal children with a 4-component model of body composition, dual-energy X-ray absorptiometry, deuterium dilution, densitometry, and skinfold thicknesses
    Marinos Elia
    Institute of Human Nutrition, University of Southampton, Southampton, United Kingdom
    Am J Clin Nutr 86:618-24. 2007
    ..The effects on and consequences of body build (dimensions, mass, and length of body segments) are unclear...
  49. ncbi Improved preparation of high molecular weight DNA for pulsed-field gel electrophoresis from mycobacteria
    V M Hughes
    Moredun Research Institute, International Research Centre, Pentlands Science Park, Bush Loan, Penicuik, Midlothian EH 29 OPZ, UK
    J Microbiol Methods 44:209-15. 2001
  50. ncbi The behaviour of bone mineral density and bone metabolism index in young and menopausal women with the consideration of body mass index
    Wiesław Tryniszewski
    Department of Radiological and Isotopic Diagnostics and Therapy, Medical University of Lodz, Poland
    Med Sci Monit 16:CR342-7. 2010
    ..The aim of the study was to evaluate the behavior of bone mineral density (BMD) and bone metabolism index (IBM) in both young women and those more than 50 years old, as associated with BMI...
  51. ncbi Ultrasound densitometric analysis of carotid plaque composition. Pathoanatomic correlation
    V Y Beletsky
    Department of Neurology, Louisiana State University Medical Center, Shreveport 71130 3932, USA
    Stroke 27:2173-7. 1996
    ..Thus, methods that can enhance ultrasonic evaluation of plaque morphology might allow a more objective means of determining carotid-mediated stroke risk...
  52. ncbi Bone biopsy and densitometry findings in a child with Camurati-Engelmann disease
    Jonas Bondestam
    Department of Pediatrics, Hospital for Children and Adolescents, P O Box 281, 00029 Helsinki, Finland
    Clin Rheumatol 26:1773-7. 2007
    ..The diagnosis was verified by detecting a mutation in exon 4 of the TGF-beta1 gene. Full body bone mineral densitometry studies performed before treatment with prednisolone were indicative for osteoporosis (Z-scores for the lumbar ..
  53. ncbi CT scan appearance, densitometry, and health status in protease inhibitor SZ alpha1-antitrypsin deficiency
    Jayne Holme
    University Hospital Birmingham NHS Foundation Trust, The University of Birmingham, Birmingham, UK
    Chest 136:1284-90. 2009
    The aim of this study was to uniquely describe CT scan appearance, densitometry, and health status in subjects with protease inhibitor SZ phenotype (PiSZ) alpha(1)-antitrypsin deficiency (AATD) compared with matched subjects with protease ..
  54. ncbi Determination of thiocolchicoside in its binary mixtures (thiocolchicoside-glafenine and thiocolchicoside-floctafenine) by TLC-densitometry
    N A El-Ragehy
    Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El Aini St, 11562 Cairo, Egypt
    Farmaco 58:463-8. 2003
    ..Assay precision using two-way ANOVA was performed on results of inter- and intra-day applications of the method...
  55. pmc Ultrasonic tissue characterization of vulnerable carotid plaque: correlation between videodensitometric method and histological examination
    Liz Andréa V Baroncini
    Department of Internal Medicine Faculdade de Medicina de Ribeirão Preto, University of Sao Paulo, Sao Paulo, Brazil
    Cardiovasc Ultrasound 4:32. 2006
  56. ncbi Quantification and facilitated comparison of von Willebrand factor multimer patterns by densitometry
    J D Studt
    Department of Haematology and Oncology, Hannover Medical School, Carl-Neuberg-Str. 1, D-30625 Hannover, Germany
    Am J Clin Pathol 116:567-74. 2001
    ..Interlaboratory comparison of results therefore may be difficult. We applied densitometry to obtain a reproducible quantification of vWF multimer patterns in healthy donors, patients with vWD variants, ..
  57. pmc Distribution and densitometry mapping of L1-CAM immunoreactivity in the adult mouse brain--light microscopic observation
    Hana Munakata
    Division of Structural Cell Biology, Nara Institute of Science and Technology, NAIST, 8916 5 Takayama, Ikoma City, Nara 630 0192, Japan
    BMC Neurosci 4:7. 2003
    ..The distribution of L1 in mouse brain might provide a basis for understanding its role in the brain...
  58. ncbi Population rates of bone densitometry use in Australia, 2001-2005, by sex and rural versus urban location
    Dan P Ewald
    Northern Rivers General Practice Network, Lismore, NSW
    Med J Aust 190:126-8. 2009
    To explore use of bone densitometry in Australia and to identify any sex and geographic differences, as a marker of osteoporosis diagnosis and care.
  59. ncbi Application of LC and HPTLC-densitometry for the simultaneous determination of benazepril hydrochloride and hydrochlorothiazide
    A el-Gindy
    Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt
    J Pharm Biomed Anal 25:171-9. 2001
    ..The two proposed methods were successfully applied to the determination of both drugs in laboratory prepared mixtures and in commercial tablets. No chromatographic interference from the tablets excipients was found...
  60. ncbi Assessment of regional progression of pulmonary emphysema with CT densitometry
    M Els Bakker
    Division of Image Processing, Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Chest 134:931-7. 2008
    Lung densitometry is an effective method to assess overall progression of emphysema, but generally the location of the progression is not estimated...
  61. ncbi An improved method using densitometry for evaluating severity of laser photocoagulation induced CNV
    R J Marano
    Department of Molecular Ophthalmology, Lions Eye Institute, Nedlands, Western Australia, Australia
    Biotech Histochem 81:59-62. 2006
    ..We describe a new method for simple and rapid evaluation of laser induced choroidal neovascularization using densitometry. Fluorescein angiograms of a laser photocoagulated rat eye were scanned into a computer...
  62. ncbi Official positions of the International Society for Clinical Densitometry
    E Michael Lewiecki
    Osteoporos Int 17:1700-1. 2006
  63. ncbi Using the osteoporosis self-assessment tool for referring older men for bone densitometry: a decision analysis
    Kouta Ito
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Am Geriatr Soc 57:218-24. 2009
    To compare health benefits and costs associated with performing bone densitometry for all men with those of risk-stratifying using the Osteoporosis Self-Assessment Tool (OST) and performing bone densitometry only for a high-risk group.
  64. ncbi Determination of the standard value of circulating blood volume during anesthesia using pulse dye-densitometry: a multicenter study in Japan
    Takehiko Iijima
    Department of Anesthesiology, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, 181 8611, Japan
    J Anesth 19:193-8. 2005
    ..The standard value for circulating blood volume (BV) during anesthesia was determined by a multicenter study in Japan. The significance of BV on the reduction of blood pressure after the induction of anesthesia was also examined...
  65. ncbi Blood volume measurement to guide fluid therapy after aneurysmal subarachnoid hemorrhage: a prospective controlled study
    Reinier Hoff
    Department of Perioperative and Emergency Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Stroke 40:2575-7. 2009
    ..In a prospective controlled study we assessed whether fluid management guided by daily measurements of blood volume (BV) reduces the incidence of severe hypovolemia compared to conventional fluid balance guided fluid therapy...
  66. ncbi Bone densitometry and the diagnosis of osteoporosis
    G M Blake
    Department of Nuclear Medicine, Guy s Hospital, London, England
    Semin Nucl Med 31:69-81. 2001
    ..Although dual x-ray absorptiometry (DXA) is the technique most associated with the recent growth in bone densitometry, several innovative devices for performing measurements at sites in the peripheral skeleton are also available...
  67. ncbi Effects of light spectrum in flatbed scanner densitometry of stained polyacrylamide gels
    Han Yen Tan
    National University of Singapore
    Biotechniques 42:474-8. 2007
    ..Based on this, we demonstrate that cost-effective densitometry can be achieved using a flatbed scanner with red light-emitting diode (LED) illumination, yielding results ..
  68. ncbi Accuracy and repeatability of blood volume measurement by pulse dye densitometry compared to the conventional method using 51Cr-labeled red blood cells
    T Imai
    Department of Critical Care Medicine, Tokyo Medical and Dental University School of Medicine, Bunkyo District, Japan
    Intensive Care Med 26:1343-9. 2000
    To determine the accuracy and repeatability of pulse dye densitometry (PDD) in measuring blood volume (BV) by comparing it with the conventional method using 51Cr-labeled red blood cells (RI method) and by assessing sequential measurements...
  69. ncbi Assessment of effective hepatic blood flow in critically ill patients by noninvasive pulse dye-densitometry
    Yasuaki Mizushima
    Osaka Prefectural Senshu Critical Care Medical Center, 2 24 Rinku Orai Kita, Izumisano, Osaka 598 0048, Japan
    Surg Today 33:101-5. 2003
    ..This study was conducted to examine the relationship between cardiac output (CO) and EHBF using pulse dye-densitometry (PDD) in nonseptic and septic patients, and to assess the prognostic value of this relationship.
  70. ncbi Calcaneal ultrasound bone densitometry is not a useful tool to screen patients with inflammatory bowel disease at high risk for metabolic bone disease
    David A Schwartz
    Inflammatory Bowel Disease Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Inflamm Bowel Dis 11:749-54. 2005
    ..This would reduce the number of patients undergoing DXA testing unnecessarily. We tried to determine if calcaneal ultrasound bone densitometry is a useful tool in screening high-risk patients with IBD for metabolic bone disease.
  71. ncbi A qualitative and quantitative HPTLC densitometry method for the analysis of cannabinoids in Cannabis sativa L
    Justin T Fischedick
    Division of Pharmacognosy, Institute of Biology, Leiden University, Leiden, The Netherlands
    Phytochem Anal 20:421-6. 2009
    ..Cannabis and cannabinoid based medicines are currently under serious investigation for legitimate development as medicinal agents, necessitating new low-cost, high-throughput analytical methods for quality control...
  72. ncbi Volumetric characterization of ester- and ether-linked lipid bilayers by pressure perturbation calorimetry and densitometry
    Nobutake Tamai
    Department of Life System, Institute of Technology and Science, The University of Tokushima, Tokushima, Japan
    Colloids Surf B Biointerfaces 92:232-9. 2012
    ..DPPC) and dihexadecylphosphatidylcholine (DHPC) membranes using pressure perturbation calorimetry (PPC) and densitometry. The ln φ(2) vs temperature curves (φ(2): apparent molar volume of phospholipid) obtained from the PPC data ..
  73. ncbi Evaluation of a femoral stem with reduced stiffness. A randomized study with use of radiostereometry and bone densitometry
    Johan Kärrholm
    Department of Orthopaedics, Sahlgren University Hospital, Goteborg, Sweden
    J Bone Joint Surg Am 84:1651-8. 2002
    ..The coating consisted of a titanium porous mesh proximally covered with a mixture of hydroxyapatite and tricalcium phosphate...
  74. ncbi Bone densitometry in children: a critical appraisal
    R R van Rijn
    Department of Radiology, Academic Medical Center Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Eur Radiol 13:700-10. 2003
    Due to the introduction of new therapeutic regimen aimed at increasing and maintaining bone mass, bone densitometry in children has gained interest...
  75. ncbi Circulating blood volume measured by pulse dye-densitometry: comparison with (131)I-HSA analysis
    T Iijima
    Department of Anesthesiology, Kyorin University School of Medicine, Mitaka City, Tokyo, Japan
    Anesthesiology 89:1329-35. 1998
    Pulse dye-densitometry (PDD) is a newly developed technique for monitoring the arterial concentration of indocyanine green. Using this method, circulating blood volume (CBV) can be calculated without using radioisotopes...
  76. ncbi Of small bones and big mistakes; bone densitometry in children revisited
    R R van Rijn
    Department of Radiology, Emma Children s Hospital Academic Medical Center Amsterdam, The Netherlands
    Eur J Radiol 71:432-9. 2009
    In this paper we discuss the bone densitometry systems available and their applicability in children and adolescents...
  77. ncbi Antimicrobial screening and quantitative determination of benzoic acid derivative of Gomphrena celosioides by TLC-densitometry
    Rute Mendonça Xavier de Moura
    Departamento de Quimica, Faculdade de Filosofia, Ciencias e Letras de Ribeirao Preto, Universidade de Sao Paulo, 14040 020 Ribeirão Preto, Sao Paulo, Brazil
    Chem Pharm Bull (Tokyo) 52:1342-4. 2004
    ..determination of 4-hydroxy-3-methoxy-benzoic acid in stems, leaves, flowers and roots was established by TLC-densitometry. Results showed significant activity against Staphylococcus aureus and Salmonella typhi...
  78. ncbi Densitometry for assessment of effect of lung volume reduction surgery for emphysema
    J Stolk
    Department of Pulmonology C3 P, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands, and Department of Radiology, University Hospital Zurich, Switzerland
    Eur Respir J 29:1138-43. 2007 lung function, the effect of resection of emphysematous tissue was studied by computed tomography (CT) densitometry. In addition, the current authors studied how surgery-induced change in emphysema related to lung density in ..
  79. ncbi High-throughput film-densitometry: an efficient approach to generate large data sets
    Dieter Typke
    Life Sciences Division, Donner Laboratory, Lawrence Berkeley National Laboratory, University of California, Berkeley, CA 94720, USA
    J Struct Biol 149:17-29. 2005
  80. ncbi High resolution MR based polymer dosimetry versus film densitometry: a systematic study based on the modulation transfer function approach
    A Berg
    Institut für Medizinische Physik, Medizinische Universität Wien, Währingerstr 13, A 1090 Wien, Austria
    Phys Med Biol 49:4087-108. 2004
  81. ncbi A quantitative histochemistry technique for measuring regional distribution of acetylcholinesterase in the brain using digital scanning densitometry
    T Ma
    Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA
    Anal Biochem 296:18-28. 2001
    ..However, they are usually time-consuming. As we report here, we adapted digital scanning densitometry to quantitate AChE histochemical staining in brain sections...
  82. pmc In vivo analysis of growth hormone receptor signaling domains and their associated transcripts
    Jennifer E Rowland
    Institute for Molecular Bioscience, University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia
    Mol Cell Biol 25:66-77. 2005
    ..These mice represent the first step in delineating the domains of the GHR regulating body growth and composition and the transcripts associated with these domains...
  83. ncbi The effect of hindlimb immobilization on acid phosphatase, metalloproteinases and nuclear factor-kappaB in muscles of young and old rats
    Marina Bar-Shai
    Department of Anatomy and Cell Biology, Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, P O Box 9649, Haifa 31096, Israel
    Mech Ageing Dev 126:289-97. 2005
    ..In conclusion, it seems that the kinetics of activation of extracellular hydrolytic and proteolytic systems differ in muscles of old animals compared to young animals...
  84. ncbi Vessel-specific regulation of angiotensin II receptor subtypes during ovine development
    Blair E Cox
    Department of Pediatrics, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Pediatr Res 57:124-32. 2005
    ..Although the mechanisms that regulate mRNA and protein expression are unclear, these changes parallel differences in VSM maturation and function and local blood flow...
  85. ncbi Downregulation of NF-kappaB activity associated with alteration in proliferative response in the spleen after burn injury
    Ho H Phan
    Department of Surgery, University of California, Davis, California, USA
    Shock 23:73-9. 2005
    ..Furthermore, the regulation of NF-kappaB may be linked to the proliferative changes seen in the spleen after burn injury...
  86. ncbi Elevated neurotrophin and neurotrophin receptor expression in spontaneously hypertensive rat lungs
    Alberto Ricci
    Unità Operativa Pneumologia, Dipartimento di Scienze Cardiovascolari e Respiratorie, Università La Sapienza Policlinico Sant Andrea, Roma, Italy
    Growth Factors 22:195-205. 2004
  87. ncbi Pharmacological and molecular comparison of K(ATP) channels in rat basilar and middle cerebral arteries
    Kenneth Beri Ploug
    Department of Neurology, Glostrup Hospital, University of Copenhagen, DK 2600 Glostrup, Denmark
    Eur J Pharmacol 553:254-62. 2006
    ..Furthermore, the results indicate that Kir6.1/SUR2B is the major K(ATP) channel complex in rat basilar and middle cerebral arteries...
  88. ncbi Stress regulation of sulfotransferases in male rat liver
    Smarajit Maiti
    Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    Biochem Biophys Res Commun 323:235-41. 2004
    ..This suggests a stress regulation mechanism of SULT2A1 at the gene transcription level, possibly occurring via hormones...
  89. ncbi [Osteoporosis: Optimizing treatment strategy]
    Thierry Thomas
    Service de Rhumatologie, INSERM E0366, Saint Etienne 42
    Presse Med 35:1543-6. 2006
    ..The minimum duration of treatment is 4-5 years, after which individual fracture risk must be reevaluated. Combinations of available drugs are not recommended for treatment of postmenopausal osteoporosis...
  90. ncbi Characterization of H2O2-induced acute apoptosis in cultured neural stem/progenitor cells
    Hsingchi J Lin
    Center for Bio Molecular Science and Engineering, Naval Research Laboratory, Washington, DC 20375, USA
    FEBS Lett 570:102-6. 2004
    ..We conclude that the transient activation of PI3K-Akt signaling delays the H2O2-induced acute apoptosis in cultured NS/PCs in part through maintaining the basal pGSK3beta level and activating other downstream effectors...
  91. ncbi Enhanced podocalyxin expression alters the structure of podocyte basal surface
    Constantinos G Economou
    Institute of Biology, National Center for Scientific Research, Demokritos, Agia Paraskevi, 15310 Athens, Greece
    J Cell Sci 117:3281-94. 2004
    ..We suggest that the observed podocalyxin-mediated inhibition of binding to the matrix could be in part responsible for the specialized conformation of the basal surface of podocytes...
  92. ncbi [Non-corticosteroid drug-induced metabolic bone disease]
    Karine Briot
    Service de Rhumatologie, Universite Rene Descartes Paris V, Hopital Cochin, Paris 75
    Presse Med 35:1579-83. 2006
    ..Other drugs responsible for bone disease include: aromatase inhibitors, GnRH agonists, anticonvulsants, heparin, and L thyroxin at TSH-suppressive doses. Confirmation is required of data about neuroleptics and antivitamin K...
  93. ncbi Identification and functional characterization of a 5-transmembrane domain variant isoform of the NTS2 neurotensin receptor in rat central nervous system
    Amelie Perron
    Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec H3A 2B4, Canada
    J Biol Chem 280:10219-27. 2005
    ..Taken together, the present results indicated that the rat vNTS2 is a functional receptor that may play a role in NT signaling in mammalian central nervous system...
  94. ncbi Prostaglandin E2 induces interleukin-8 gene transcription by activating C/EBP homologous protein in human T lymphocytes
    Silvana Caristi
    Department of Experimental Pathology and Microbiology, University of Messina, 98125 Messina, Italy
    J Biol Chem 280:14433-42. 2005
    ..These findings show the complexity with which PGE(2) regulates IL-8 synthesis by inhibiting or enhancing its production depending on the cell types and environmental conditions...
  95. ncbi Prognostic significance of metastasis-associated protein S100A4 (Mts1) in prostate cancer progression and chemoprevention regimens in an autochthonous mouse model
    Mohammad Saleem
    Department of Dermatology, University of Wisconsin Madison, Wisconsin 53706, USA
    Clin Cancer Res 11:147-53. 2005
    ..Because oral consumption of green tea polyphenols (GTP) has been shown to inhibit metastasis and prostate cancer in TRAMP, we further assessed the significance of S100A4 during chemoprevention regimen...
  96. ncbi Differential expression and processing of chromogranin A and secretogranin II in relation to the secretory status of endocrine cells
    J R Peinado
    Department of Cell Biology, Physiology, and Immunology, Campus de Rabanales Edificio Severo Ochoa, Planta 3, University of Cordoba, E 14014 Cordoba, Spain
    Endocrinology 147:1408-18. 2006
    ..Thus, SgII expression is strongly related to the secretory activity of melanotrope cells, whereas CgA expression may not be related to secretory rate, but, rather, to hormone storage in this endocrine cell type...
  97. ncbi Targeted knockdown of G protein subunits selectively prevents receptor-mediated modulation of effectors and reveals complex changes in non-targeted signaling proteins
    Andrejs M Krumins
    Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    J Biol Chem 281:10250-62. 2006
    ..These findings provide a foundation for understanding the mechanisms that regulate the adaptability and remarkable resilience of G protein signaling networks...
  98. ncbi 3,4-Methylenedioxymethamphetamine (MDMA), but not morphine, alters APP processing in the rat brain
    Janos Kalman
    Department of Psychiatry and Alzheimer s Disease Research Centre, Albert Szent Györgyi Center for Medical and Pharmaceutical Sciences, Faculty of Medicine, University of Szeged, Szeged, Hungary
    Int J Neuropsychopharmacol 10:183-90. 2007
    ..These results indicate that the chronic use of 'ecstasy', but not morphine, may be harmful via a novel mode of action, i.e. by altering the APP expression and processing in the brain...
  99. ncbi Vascular endothelial growth factor (VEGF) in human tooth germ center
    F Mastrangelo
    Oral Surgery of Oral Science Department, University G D Annunzio, Chieti, Italy
    Int J Immunopathol Pharmacol 18:587-94. 2005
    ..Additionally, a positive reaction was observed for the VEGF protein in the cells of the stellate reticulum and in those endothelial tissue surrounding the microvessels in all the samples examined...
  100. ncbi Expression of SPARC in normal and fibrotic livers
    E Frizell
    Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA
    Hepatology 21:847-54. 1995
    ..These studies demonstrate the increased expression of SPARC--a protein that modulates cell shape and disrupts cell-matrix interactions--during the initial stages of hepatic fibrosis...
  101. ncbi Mitochondrial NOS upregulation during renal I/R causes apoptosis in a peroxynitrite-dependent manner
    J L Viñas
    Department of Experimental Pathology, Instituto de Investigaciones Biomedicas, IIBB CSIC, IDIBAPS, Barcelona, Spain
    Kidney Int 69:1403-9. 2006

Research Grants63

  1. Ethanol Regulation of Serum Glucocorticoid Kinase I
    BLAIR N COSTIN; Fiscal Year: 2012
    ..measuring Sgk1 protein and isoform levels following acute ethanol exposure through western blotting followed by densitometry analysis and the quantitative polymerase chain reaction (Q-rtPCR)...
  2. Validation of Novel Infertility Biomarker
    PETER SUTOVSKY SUTOVSKY; Fiscal Year: 2012
    ..microscopic analysis of immunolabeled spermatozoa, and by semi-quantitative western blotting/densitometry technique...
  3. Novel Risk Factors for Vertebral Fractures in Health and Chronic Kidney Disease
    Julie Paik; Fiscal Year: 2013
    ..Rosen, MD, an endocrinologist with clinical expertise in osteoporosis, bone health, and clinical densitometry and Director of the Osteoporosis Prevention and Treatment Center at BIDMC;and Jerome Ackerman, PhD, Director of ..
  4. Robust BCT for Clinical Use
    DAVID KOPPERDAHL; Fiscal Year: 2010
    ..With substantial reimbursement cuts being introduced by Medicare for bone densitometry by dual energy X-ray absorptiometry (DXA, the current clinical standard), with a sensitivity of DXA for ..
    Ralph L Sacco; Fiscal Year: 2013
    ..and adiponectin, a new marker of obesity, new measures of subclinical carotid disease (carotid plaque area and densitometry), and quantitative MRI measures of vascular subclinical brain disease, as well as evaluate the impact on ..
  6. Epidemiology of lens aging in older women
    JASON LEIGH SANDERS; Fiscal Year: 2013 cycle, we will add a measure of lens transparency using Scheimpflug photography, which uses linear densitometry to provide a quantitative measure of transparency...
  7. Adenosine Receptors and Ethanol Withdrawal
    TRACY RENEE BUTLER; Fiscal Year: 2010
    ..Slices will be visualized using fluorescent microscopy and data will be quantified using densitometry and confocal imaging...
  8. A Novel Human DNA Damage Response Which Directly Alters DNA Polymerase Delta
    ..This will be done through Western blotting and densitometry. In addition, cell lines which are deficient in specific DNA damage response proteins (such as p53 or ATM) will ..
  9. Neonatal Methamphetamine Effects on Adult Cholinergic and Cognitive Function
    Jessica A Siegel; Fiscal Year: 2010
    ..This will be achieved using immunohistochemistry and confocal microscopy with densitometry and unbiased stereological techniques;2) determine the effects of neonatal MA on the number and affinity of M1 ..
  10. Combining Imaging and Modeling in Osteoporosis Fracture Risk Assessment
    GARY BEAUPRE; Fiscal Year: 2009
    ..The specific densitometry technologies to be assessed were chosen so that the results will have the broadest possible impact for ..
  11. Role of Notch Signaling in Osteocytes
    Ernesto Canalis; Fiscal Year: 2013
    ..of mice misexpressing Notch will be compared to that of wild type mice and determined by contact radiography, densitometry, micro CT scanning and histomorphometry...
  12. Growth Factors;Effect on Aspects of Bone Formation
    Ernesto Canalis; Fiscal Year: 2012
    ..mice will be compared to that of wild type mice and determined by histomorphometry, contact radiography, densitometry and micro CT scanning;2) To determine the function of Nov in vivo by targeted gene deletion...
  13. Stress History is Recorded in Tooth Enamel
    SHANE NEWPORT WHITE; Fiscal Year: 2012
    ..We have recently shown that an enamel biomarker corresponds to body size and to lamellar bone densitometry, confirming it as a surrogate for other important patterns of body regulation...
  14. Mechanisms of Cortisol and Notch Action in Bone
    Ernesto Canalis; Fiscal Year: 2012
    ..HES-1 will be compared to that of wild type mice and determined by histomorphometry, contact radiography, densitometry and micro CT scanning;and 3) To determine the mechanism of action of HES-1 in vitro and signals responsible for ..
  15. Fetal Programming and Human Physical Performance
    Tom Brutsaert; Fiscal Year: 2009
    ..We will also measure body composition via hydro-densitometry and insulin resistance via an oral glucose tolerance test, both before and after training...
  16. Multiethnic Study of Breast Arterial Calcium Gradation and CVD
    Sabee Molloi; Fiscal Year: 2012
    ..A new, validated densitometry method will be used to estimate BAC mass (in milligrams) using digital mammograms;2) To document race/ethnic ..
  17. Tissue and Airway Analysis for Emphysema Interventions
    Juerg Tschirren; Fiscal Year: 2012
    ..II SBIR, (Tissue and Airway Assessment for Emphysema Interventions) which resulted in an FDA approved lung densitometry and airway measurement software application...
  18. Alterations of the Synaptic Transcriptome in Response to Repeated Ethanol
    MEGAN ANNE O'BRIEN; Fiscal Year: 2012
    ..Western blot analysis followed by densitometry will be used to quantitate the changes in synaptic proteins encoded by targeted transcripts...
  19. Phase 2 Study of Magnesium Supplements in the Treatment of PXE
    Mark Lebwohl; Fiscal Year: 2013
    ..biopsy of target lesion, ophthalmologic evaluations, photographs of skin lesions, electrocardiogram, and bone densitometry. Upon completion of the first year, barring any safety concerns, all subjects will be administered magnesium ..
  20. Multi-view, Photon Counting DXA Scanner for Quantitative Musculoskeletal Imaging
    Thomas J Beck; Fiscal Year: 2011
    ..PUBLIC HEALTH RELEVANCE: Bone densitometry scanners are designed to measure bone density as way to determine if patients are susceptible to osteoporotic ..
    Henry Chambers; Fiscal Year: 1993
    ..Amounts of protein are measured by scanning densitometry. Factors that influence autolytic activity, and which may regulate expression of methicillin resistance, will ..
  22. Tracking change in rod, cone, and RPE mosaics independently in geographic atrophy
    Ethan A Rossi; Fiscal Year: 2011
    ..Using high resolution retinal densitometry in AOSLO, we will assess changes in photoreceptor function that accompany structural changes in geographic ..
  23. Dopamine levels in postmortem human nucleus accumbens in schizophrenia
    Lesley A McCollum; Fiscal Year: 2013 determined in control subjects compared to groups of off- and on-drug schizophrenia subjects using optical densitometry and western blot assays...
    Scott Going; Fiscal Year: 1991 that more accurate estimates of body composition can be developed for these age groups for such methods as densitometry, hydrometry, anthropometry, and total body electrical impedance...
    Allan Brasier; Fiscal Year: 1993
    ..Subsequent quantitation of the developed autoradiographic film is performed by scanning laser densitometry, a labor-intensive and time consuming process that depends on empiric (and frequently multiple) film exposures...
  26. Improved Zwitterions for Proteomics
    LEO RODKEY; Fiscal Year: 2005
    ..Patterns of ampholyte distribution will be analyzed by image analysis densitometry to assure smooth uninterrupted distribution across the pH gradient...
    Marja Hurley; Fiscal Year: 2003
    ..Dynamic histomorphometry and bone densitometry will be performed on mice of different ages to determine the rate that decreased trabecular bone volume in FGF-..
    THOMAS SEYFRIED; Fiscal Year: 1992
    ..and the individual ganglioside species will be analyzed using high performance thin-layer chromatography and densitometry. A specific objective will be to determine if the ganglioside abnormalities are a primary or secondary effect ..
    Mira Edgerton; Fiscal Year: 1991
    ..individual salivary components, and their quantitation by immunodot blotting coupled with scanning laser densitometry. The potential role of salivary mucins and secretory IgA in the adherence of Streptococcus and Actinomyces ..
    Arezoo Campbell; Fiscal Year: 2003
    ..will be compared, based (a) on electrophoresis and ethidium bromide staining of the amplified DNA and densitometry of the band obtained: (b) measurement of fluorescence produced following reaction of the PCR mixture with the ..
    William Burke; Fiscal Year: 1993
    ..CA enzyme mRNA levels will be measured using polymerase chain reaction with autoradiography and quantitative densitometry. 4...
    Neil Kaplowitz; Fiscal Year: 1999
    ..We will use quantitative densitometry of autoradiographs and HPLC of biopsies of the perfused rat liver to study the zonation of sulfur amino acid ..
  33. X-Ray Scattering Bone Densitometry
    MIODRAG KRMAR; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  34. Vertebral Fracture: Trabecular Bone Structure Assessment
    Sharmila Majumdar; Fiscal Year: 2006
    ..Current assessment of osteoporotic fracture risk is based on bone densitometry techniques that do not entirely predict fracture risk or the impact of a particular intervention...
    M Clark; Fiscal Year: 2000
    ..Bone mineral density of the femoral neck and lumbar spine will be measured using dual energy x-ray densitometry. Biological and self- reported factors which may impact bone density will also be evaluated...
  36. Improving BMP retention and healing in engineered bone
    ELSA BROCHMANN MURRAY; Fiscal Year: 2007
    ..of BMP-2-mediated healing in vivo in a rabbit critical-sized calvarial defect repaired with a BMSC/HA SBGS by densitometry, microCT scanning, and quantitative static and dynamic bone histomorphometry as part of developing a cheaper ..
  37. Rett syndrome: determinants of outcome and burden
    Helen Leonard; Fiscal Year: 2007
    ..In 2003 and 2005 clinical assessments or clinical file review will provide EEG, ECG, blood parameters, bone densitometry and autonomic nervous system data...
    Robert Burke; Fiscal Year: 1993
    ..Quantitative assessment of changes in fiber density and distribution will be performed by densitometry and image analysis...
    Roger Warnke; Fiscal Year: 1993
    ..Quantitation of immunostained cells both in frozen and paraffin sections will employ video densitometry/image analysis...
  40. Volume and Morphology of Fibroglandular Tissue for Breast Cancer Risk Prediction
    MIN YING L SU; Fiscal Year: 2013
    ..will be made available for sharing, and it will provide a very useful tool for researchers in the breast densitometry research field to analyze large datasets...
    Felix Wehrli; Fiscal Year: 2000
    ..BVF), a single-modality examination that evaluates both R2' and BVF, better predicts fractures than bone densitometry. We shall examine the above hypothesis by pursuing the aims below; specifically, we shall 1...
    Theresa Scholl; Fiscal Year: 2000
    ..2: To measure maternal blood lead levels and bone (by dual X-ray densitometry, os calcis ultrasound and bone turnover markers) in adolescent and adult women at parturition and at 3, 6, 12 ..
    MATTHEW BOEGEHOLD; Fiscal Year: 2003
    ..These hypotheses will be tested by using Western analysis and densitometry to quantify the expression of xanthine-oxidase and NAD(P)H oxidase (oxidant-generating enzymes) as well as ..
    STEVEN BRADWAY; Fiscal Year: 1990
    ..of mucosal pellicle components will be carried out using immuno-dot blotting coupled with scanning laser densitometry. In Phase II, the nature of candida-salivary interactions will be studied...
  45. 4th International Conference on Children's Bone Health
    Mary Leonard; Fiscal Year: 2007
    ..3) to have attendees provide substantial input and public comment on the International Society for Clinical Densitometry evidence-based guidelines for the assessment of bone density in children...
    RICHARD DEY; Fiscal Year: 1991
    ..imaging needs of the group include threshholding and segmentation, image capture, size sorting, edge detection, densitometry, morphometry, low level fluorescence detection, fluorescence ratio imaging and three dimensional reconstruction ..
    Anne Fulton; Fiscal Year: 1992
    ..Photon-counting densitometry, measurements of the Stiles-Crawford effect and Westheimer functions will be added to the probes of retinal ..
    STEVEN ARNOLD; Fiscal Year: 1999
    ..immunohistochemical and other molecular methods and will be quantified with particle counting and/or optical densitometry using principles of stereology and systematic sampling...
    Frank DiBianca; Fiscal Year: 1993
    This grant application proposes the development of two new imaging techniques for bone densitometry and their evaluation by performance comparisons with a commercial bone densitometer...
  50. Improving the Accuracy of Pediatric DXA Bone Studies
    Vicente Gilsanz; Fiscal Year: 2009
    ..In this regard, the official position of the International Society for Clinical Densitometry states its recent recommendations that subjects <20 years of age should not be diagnosed with osteoporosis ..
    HOWARD BAKER; Fiscal Year: 1990
    ..The technique of retinal densitometry is used to examine pigment density and pigment regeneration after bleaching for both rods and foveal cones in ..
    Sven Prevrhal; Fiscal Year: 2003
    ..The clinically established method to predict a person's hip fracture risk, bone densitometry, cannot separately measure the status of trabecular and cortical bone but only reports overall bone density...
    Robert Shaye; Fiscal Year: 1991
    ..Therapeutics of the University of Florida's College of Pharmacy and Medicine request a shared Quantitative Densitometry Instrument...
    Joan Lappe; Fiscal Year: 2001 pubertal females who consume a high calcium diet will have a greater increase bone quality, as measured by densitometry and ultrasound, than pubertal females who consume their usual dietary calcium intake...
    JOHN VANDEBERG; Fiscal Year: 2002
    ..The procedures areas include treatment rooms, surgical suites, x-ray rooms, ultrasound room, densitometry room, neonatal intensive care unit, necropsy, pathology laboratories and tissue samples storage...
    DENNIS DACEY; Fiscal Year: 2002
    ..connections of the long (L) and middle (M) wavelength-sensitive cone types using a new method of reflection densitometry and electron microscopy: the hypothesis that the L and M cone types form non-randomly distributed submosaics ..
    Grazyna Rajkowska; Fiscal Year: 2001
    ..and examine the cytoarchitecture of this cortex in the four diagnostic groups; 3) reveal the autoradiographic densitometry of catecholaminergic and serotonergic receptors in prefrontal cortex of the four groups; 4) and compare ..
    Dennis Leavitt; Fiscal Year: 1993
    ..These calculations will be verified both for fixed-field and arc irradiations using head phantoms and film densitometry. Computer calculation of isodose distributions and dose volume histograms will be used to compare radiosurgery ..
    Jair Soares; Fiscal Year: 2004
    ..phosphoinositides, which will be done with two-dimensional thin-layer chromotography followed by scanning laser densitometry. They will also undergo a 1...
    William Balch; Fiscal Year: 1993
    ..Standard approaches using autoradiography and densitometry lack sensitivity, linearity and a dynamic exposure range to generate accurate quantitative results without ..
  61. The Role of CDK4 in Bone Formation
    Fayez Safadi; Fiscal Year: 2003
    ..Previous studies showed that CDK4-/-mice compared to age-matched, wild-type (+/+) mice. Densitometry by peripheral quantitative computerized tomography (pQCT) showed a reduction in trabecular bone density in CDK4 ..
  62. Proteome Markers for Alzheimer's Disease Diagnosis
    Kelvin Lee; Fiscal Year: 2004
    ..protein markers used in proteome analysis that includes high solution two-dimensional electrophoresis, laser densitometry, fluorescence imaging, and computer aided in each analysis (Specific Aim 2)...
    Om Mishra; Fiscal Year: 2008
    ..abstract_text> ..