powder diffraction

Summary

Summary: Method of using a polycrystalline powder and Rietveld refinement (LEAST SQUARES ANALYSIS) of X-RAY DIFFRACTION or NEUTRON DIFFRACTION. It circumvents the difficulties of producing single large crystals.

Top Publications

  1. ncbi Structural characterization of anhydrous naloxone- and naltrexone hydrochloride by high resolution laboratory X-ray powder diffraction and thermal analysis
    Kunihisa Sugimoto
    Max Planck Institute for Solid State Research, Heisenbergstrasse 1, Stuttgart, Germany
    J Pharm Sci 96:3316-23. 2007
  2. pmc Green synthesis of silver/montmorillonite/chitosan bionanocomposites using the UV irradiation method and evaluation of antibacterial activity
    Kamyar Shameli
    Department of Chemistry, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
    Int J Nanomedicine 5:875-87. 2010
  3. pmc Development of antiproliferative nanohybrid compound with controlled release property using ellagic acid as the active agent
    Mohd Zobir Hussein
    Advanced Materials and Nanotechnology Laboratory, Institute of Advanced Technology, Selangor, Malaysia
    Int J Nanomedicine 6:1373-83. 2011
  4. pmc Controlled release and angiotensin-converting enzyme inhibition properties of an antihypertensive drug based on a perindopril erbumine-layered double hydroxide nanocomposite
    Samer Hasan Hussein Al Ali
    Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
    Int J Nanomedicine 7:2129-41. 2012
  5. ncbi Nanoemulsion-templated shell-crosslinked nanocapsules as drug delivery systems
    Wei He
    School of Pharmacy, Fudan University, Key Laboratory of Smart Drug Delivery of Ministry of Education and PLA, Shanghai 201203, PR China
    Int J Pharm 445:69-78. 2013
  6. ncbi Piroxicam/2-hydroxypropyl-beta-cyclodextrin inclusion complex prepared by a new fluid-bed coating technique
    Xingwang Zhang
    School of Pharmacy, Fudan University, Shanghai, China
    J Pharm Sci 98:665-75. 2009
  7. ncbi Characterization and stability analysis of zinc oxide nanoencapsulated conjugated linoleic acid
    Jin Ho Choy
    Dept of Chemistry, Ewha Womans Univ, Seoul, Korea
    J Food Sci 75:N63-8. 2010
  8. ncbi Neutron powder diffraction studies of silicon-substituted hydroxyapatite
    Th Leventouri
    Physics Department, Florida Atlantic University, Boca Raton, FL 33431, USA
    Biomaterials 24:4205-11. 2003
  9. ncbi Structural characterization of iron oxide/hydroxide nanoparticles in nine different parenteral drugs for the treatment of iron deficiency anaemia by electron diffraction (ED) and X-ray powder diffraction (XRPD)
    S Futterer
    Institute of Pharmacy and Biochemistry, Johannes Gutenberg University Mainz, D 55099 Mainz, Germany Electronic address
    J Pharm Biomed Anal 86:151-60. 2013
  10. pmc Synthesis and characterization of silver/talc nanocomposites using the wet chemical reduction method
    Kamyar Shameli
    Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Selangor, Malaysia
    Int J Nanomedicine 5:743-51. 2010

Research Grants

Detail Information

Publications299 found, 100 shown here

  1. ncbi Structural characterization of anhydrous naloxone- and naltrexone hydrochloride by high resolution laboratory X-ray powder diffraction and thermal analysis
    Kunihisa Sugimoto
    Max Planck Institute for Solid State Research, Heisenbergstrasse 1, Stuttgart, Germany
    J Pharm Sci 96:3316-23. 2007
    ..naloxone and naltrexone hydrochloride were determined ab initio from high resolution laboratory X-ray powder diffraction data...
  2. pmc Green synthesis of silver/montmorillonite/chitosan bionanocomposites using the UV irradiation method and evaluation of antibacterial activity
    Kamyar Shameli
    Department of Chemistry, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
    Int J Nanomedicine 5:875-87. 2010
    ..These results show that Ag/MMT/Cts BNCs can be useful in different biologic research and biomedical applications, such as surgical devices and drug delivery vehicles...
  3. pmc Development of antiproliferative nanohybrid compound with controlled release property using ellagic acid as the active agent
    Mohd Zobir Hussein
    Advanced Materials and Nanotechnology Laboratory, Institute of Advanced Technology, Selangor, Malaysia
    Int J Nanomedicine 6:1373-83. 2011
    ..In vitro bioassay study showed that the EAN has a mild effect on the hepatocytes cells, similar to its counterpart, free EA...
  4. pmc Controlled release and angiotensin-converting enzyme inhibition properties of an antihypertensive drug based on a perindopril erbumine-layered double hydroxide nanocomposite
    Samer Hasan Hussein Al Ali
    Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
    Int J Nanomedicine 7:2129-41. 2012
    ..By virtue of the ion-exchange properties of layered double hydroxide, perindopril erbumine was released in a sustained manner. Therefore, this intercalated material can be used as a controlled-release formulation...
  5. ncbi Nanoemulsion-templated shell-crosslinked nanocapsules as drug delivery systems
    Wei He
    School of Pharmacy, Fudan University, Key Laboratory of Smart Drug Delivery of Ministry of Education and PLA, Shanghai 201203, PR China
    Int J Pharm 445:69-78. 2013
    ..Furthermore, the presence of surface food proteins introduces carboxyl and amine moieties, which enables the nanocapsules to anchor ligands, suggesting its potential application in targeting drug delivery, bioimaging and therapeutics...
  6. ncbi Piroxicam/2-hydroxypropyl-beta-cyclodextrin inclusion complex prepared by a new fluid-bed coating technique
    Xingwang Zhang
    School of Pharmacy, Fudan University, Shanghai, China
    J Pharm Sci 98:665-75. 2009
    ..Solid-state (13)C NMR spectrometry indicated possible inclusion of PIX through the pyridine ring. It is concluded that fluid-bed coating has potential to be used as a new technique to prepare cyclodextrin inclusion complex...
  7. ncbi Characterization and stability analysis of zinc oxide nanoencapsulated conjugated linoleic acid
    Jin Ho Choy
    Dept of Chemistry, Ewha Womans Univ, Seoul, Korea
    J Food Sci 75:N63-8. 2010
    ..Nanoencapsulation improved the thermal stability of CLA by about 25%, compared to pristine CLA. Practical Application: This system can be used for protection of encapsulated negatively-charged food ingredients from thermal processing...
  8. ncbi Neutron powder diffraction studies of silicon-substituted hydroxyapatite
    Th Leventouri
    Physics Department, Florida Atlantic University, Boca Raton, FL 33431, USA
    Biomaterials 24:4205-11. 2003
    ..4wt% silicon-substituted HAp prepared by an aqueous precipitation method. High-resolution neutron powder diffraction and Rietveld refinement methods were used to investigate the effect of silicon substitution on the crystal ..
  9. ncbi Structural characterization of iron oxide/hydroxide nanoparticles in nine different parenteral drugs for the treatment of iron deficiency anaemia by electron diffraction (ED) and X-ray powder diffraction (XRPD)
    S Futterer
    Institute of Pharmacy and Biochemistry, Johannes Gutenberg University Mainz, D 55099 Mainz, Germany Electronic address
    J Pharm Biomed Anal 86:151-60. 2013
    ..X-ray powder diffraction (XRPD) and electron diffraction (ED) methods were used in order to investigate the nine different parenteral ..
  10. pmc Synthesis and characterization of silver/talc nanocomposites using the wet chemical reduction method
    Kamyar Shameli
    Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Selangor, Malaysia
    Int J Nanomedicine 5:743-51. 2010
    ..These Ag/talc-NCs may have potential applications in the chemical and biological industries...
  11. ncbi Controlled release of donepezil intercalated in smectite clays
    Jin Kuen Park
    Center for Intelligent Nano Bio Material CINBM, Division of Nanoscience and Department of Chemistry, Ewha Womans University, Seoul 120 750, Republic of Korea
    Int J Pharm 359:198-204. 2008
    ..Therefore, to formulate a complete drug delivery system, the hybrids were coated with Eudragit E-100 using a spray dryer, which also showed great enhancement in the release rate during a short period of time (180min)...
  12. ncbi High-throughput phase-diagram mapping via powder diffraction: a case study of HEWL versus pH
    Sebastian Basso
    European Synchrotron Radiation Facility, Grenoble, France
    Acta Crystallogr D Biol Crystallogr 61:1612-25. 2005
    ..The Rietveld analysis gave an average structural model with excellent goodness of fit and stereochemistry...
  13. ncbi Subtleties in crystal structure solution from powder diffraction data using simulated annealing: ranitidine hydrochloride
    Ashfia Huq
    Department of Physics and Astronomy, State University of New York at Stony Brook, Stony Brook, New York 11794 3800, USA
    J Pharm Sci 92:244-9. 2003
    ..We redetermine the structure from powder data using simulated annealing and show that the conformational disorder is clearly revealed by this method...
  14. pmc Fabrication of silver nanoparticles doped in the zeolite framework and antibacterial activity
    Kamyar Shameli
    Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Selangor, Malaysia
    Int J Nanomedicine 6:331-41. 2011
    ..All of the synthesized Ag/zeolite NCs were found to have antibacterial activity. These results show that Ag NPs in the zeolite framework can be useful in different biological research and biomedical applications...
  15. ncbi Synchrotron X-ray powder diffraction study of hexagonal turkey egg-white lysozyme
    Irene Margiolaki
    European Synchrotron Radiation Facility, BP 220, F 38043, Grenoble Cedex 9, France
    Acta Crystallogr D Biol Crystallogr 61:423-32. 2005
    The structure of turkey egg-white lysozyme (TEWL) has been refined from high-resolution X-ray powder diffraction data. The sample was rapidly obtained as a polycrystalline precipitate at high protein concentration using 0...
  16. ncbi X-ray powder diffraction patterns for certain fluoroquinolone antibiotic drugs
    Subbiah Thangadurai
    Department of Geology and Mining, Guindy, Chennai 600 032, India
    Acta Pharm 53:295-303. 2003
    X-ray powder diffraction (XRD) data for six pure fluoroquinolone antibiotic drugs, ciprofloxacin, norfloxacin, enrofloxacin, ofloxacin, pefloxacin and sparfloxacin have been obtained using a powder diffractometer...
  17. ncbi Powder crystallography on macromolecules
    I Margiolaki
    European Synchrotron Radiation Facility ESRF, Grenoble, France
    Acta Crystallogr A 64:169-80. 2008
    ..A wide range of small proteins have been found to give synchrotron powder diffraction profiles where the peak widths are essentially limited only by the instrumental resolution...
  18. ncbi Second SH3 domain of ponsin solved from powder diffraction
    Irene Margiolaki
    European Synchrotron Radiation Facility, ESRF, BP 220, F 38043, Grenoble, France
    J Am Chem Soc 129:11865-71. 2007
    ..seems to be no fundamental reason, except the sheer size and complexity of the structures involved, why powder diffraction should not be employed to solve structures of small proteins...
  19. ncbi Determination of the degree of deacetylation of chitin and chitosan by X-ray powder diffraction
    Yongqin Zhang
    Department of Food Science and Engineering, Ocean University of China, Qingdao 266003, China
    Carbohydr Res 340:1914-7. 2005
    ..the degree of deacetylation (DD) of alpha-chitin and chitosan in the range of 17-94% DD using X-ray powder diffraction (XRD) is proposed...
  20. ncbi Monetite formed in mixed solvents of water and ethylene glycol and its transformation to hydroxyapatite
    Ming guo Ma
    State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Biomaterials and Tissue Engineering Research Center, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, People s Republic of China
    J Phys Chem B 110:14226-30. 2006
    ..The products were characterized by X-ray powder diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Fourier transform ..
  21. ncbi Electron paramagnetic resonance, scanning electron microscopy with energy dispersion X-ray spectrometry, X-ray powder diffraction, and NMR characterization of iron-rich fired clays
    Federica Presciutti
    Chemistry Department and Center SMAArt, University of Perugia, Via Elce di Sotto 8, 06123 Perugia, Italy
    J Phys Chem B 109:22147-58. 2005
    ..paramagnetic resonance, scanning electron microscopy with electron dispersion X-ray spectrometry, X-ray powder diffraction, magic angle spinning and multiple quantum magic angle spinning NMR...
  22. ncbi In vivo and in vitro evaluation of a solid dispersion system of gliclazide:PEG 6000
    Sukmadjaja Asyarie
    Pharmaceutics Research Group, School of Pharmacy, Institut Teknologi Bandung, Ganesha 10 Bandung 40132, Bandung, Indonesia
    PDA J Pharm Sci Technol 61:400-10. 2007
    ..In this study, polyethylene glycol (PEG) 6000 was used as a matrix to disperse gliclazide in the solid state, and the pharmacokinetic profile of this solid dispersion was studied in rats...
  23. ncbi Miniaturized assay for solubility and residual solid screening (SORESOS) in early drug development
    Nicole Wyttenbach
    Department of Preclinical Research, Pharma Division, F Hoffmann La Roche Ltd, Bldg 093 724, CH 4070, Basle, Switzerland
    Pharm Res 24:888-98. 2007
    ..The aim was to develop a miniaturized method for solubility and residual solid screening of drug compounds in aqueous and non-aqueous vehicles in early drug development...
  24. ncbi Physicochemical properties of tamoxifen hemicitrate sesquihydrate
    Takashi Kojima
    Department of Pharmaceutical Technology, Kobe Pharmaceutical University, Higashinada, Kobe 658 8558, Japan
    Int J Pharm 352:146-51. 2008
    ....
  25. ncbi Detection of lot-to-lot variations in the amorphous microstructure of lyophilized protein formulations
    Yutaka Hirakura
    Pharmaceutical Analysis, Pharmaceutical Research and Technology Laboratories, Astellas Pharma Inc, 180 Ozumi, Yaizu, Shizuoka 425 0072, Japan
    Int J Pharm 340:34-41. 2007
    ..This study demonstrates the usefulness of TSDC in the analysis of lot-to-lot variations in amorphous pharmaceuticals...
  26. ncbi Crystallization of carbamazepine pseudopolymorphs from nonionic microemulsions
    Anna Kogan
    Casali Institute of Applied Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Langmuir 24:722-33. 2008
    ..Crystallization from microemulsion media enabling one to obtain the drug (CBZ) with predicted structure and morphology should be of great significance for pharmaceutical applications...
  27. ncbi Applications of solid-state NMR to pharmaceutical polymorphism and related matters
    Robin K Harris
    Department of Chemistry, University of Durham, South Road, Durham, DH1 3LE, UK
    J Pharm Pharmacol 59:225-39. 2007
    ..1%). Additional strength is being derived from computation of chemical shifts in solids, using a code that takes account of the spatial repetition inherent in crystalline materials...
  28. pmc Quantitative measurement of indomethacin crystallinity in indomethacin-silica gel binary system using differential scanning calorimetry and X-ray powder diffractometry
    Xiaohong Pan
    School of Pharmacy, University of Maryland, 20 North Pine Street, Baltimore, MD 21201, USA
    AAPS PharmSciTech 7:E11. 2006
    ..DSC demonstrated greater sensitivity and had less variation in measurement than XRPD in quantifying crystalline IMC in the IMC-SG binary system...
  29. ncbi Development and optimization of solid dispersion containing pellets of itraconazole prepared by high shear pelletization
    Guanhao Ye
    Department of Pharmaceutics, Shenyang Pharmaceutical University, No 103 Wenhua Road, Shenyang 110016, PR China
    Int J Pharm 337:80-7. 2007
    ..a simple fusion method followed by powdered and characterized by differential scanning calorimetry and X-ray powder diffraction. Solid dispersions containing pellets were consequently prepared using a lab-scale high shear mixer...
  30. ncbi Investigations of the effect of the lipid matrix on drug entrapment, in vitro release, and physical stability of olanzapine-loaded solid lipid nanoparticles
    K Vivek
    Drug Delivery Research Laboratory, Center of Relevance and Excellence in NDDS, Pharmacy Department, GH Patel Building, Donor s Plaza, Fatehgunj, M S University, Baroda 390002, Gujarat, India
    AAPS PharmSciTech 8:E83. 2007
    ..A significant increase in size and zeta potential was observed for GTS SLN and WE 85 SLN dispersions stored at 40 degrees C. Release of OL from the SLNs was sustained up to 48 hours in pH 7.4 PB and obeyed Higuchi's release kinetics...
  31. pmc Investigation of the solid state properties of amoxicillin trihydrate and the effect of powder pH
    Alireza Ghassempour
    Medicinal Plants and Drugs Research Institute MPDRI, Shahid Beheshti University, Evin, PO Box 19835 389, Tehran, Iran
    AAPS PharmSciTech 8:E93. 2007
    ..Recrystallization studies confirmed that the powder pH could be controlled by adjusting the pH of the crystallization...
  32. ncbi Molecular structure of a D-homoandrostanyl steroid derivative: single crystal and powder diffraction analyses
    P Martinetto
    Laboratoire de Cristallographie, UPR 5031, CNRS, 25 Avenue des Martyrs, BP166, 30842 Grenoble, France
    J Phys Chem B 110:15127-33. 2006
    ..diffractometry is the method of choice when it comes to crystal structure determination, methods using powder diffraction data become more and more competitive...
  33. pmc Crystal structure determination of new antimitotic agent bis(p-fluorobenzyl)trisulfide
    Haoyun An
    ACEA Biosciences, Inc, 6779 Mesa Ridge Road, Suite 100, San Diego, CA 92121, USA
    AAPS PharmSciTech 9:551-6. 2008
    ..Methods used included X-ray single crystal diffraction, X-ray powder diffraction (XRPD), Fourier-transform infrared (FT-IR) spectroscopy, differential scanning calorimetric (DSC) and ..
  34. ncbi Physicochemical, in silico and in vivo evaluation of a danazol-beta-cyclodextrin complex
    G S Jadhav
    Pharmaceutical Division, Mumbai University Institute of Chemical Technology, N P Marg, Matunga, Mumbai 400019, India
    Int J Pharm 352:5-16. 2008
    ..Moreover, in mouse model, danazol-beta-cyclodextrin complex at 51.2mg/kg (equivalent to 400mg human dose) showed 100% anovulation when given orally...
  35. ncbi The salt-cocrystal continuum: the influence of crystal structure on ionization state
    Scott L Childs
    SSCI, Inc, an Aptuit company, 3065 Kent Avenue, West Lafayette, Indiana 47906, USA
    Mol Pharm 4:323-38. 2007
    ..We propose modifications to the DeltapK(a) rule for selecting salt screen counterions that focus on the discovery of solid forms with useful physical properties rather than an arbitrary cutoff value for DeltapK(a)...
  36. ncbi Preparation and characterization of etoricoxib-beta-cyclodextrin complexes prepared by the kneading method
    Haresh M Patel
    Department of Quality Assurance, L M College of Pharmacy, Navrangpura, Ahmedabad 380009 India
    Acta Pharm 57:351-9. 2007
    ..The dissolution of etoricoxib was notably increased as compared to pure drug as well as its physical mixture. The complex showed more than 75% drug released in 30 min...
  37. ncbi Co-crystals of caffeine and hydroxy-2-naphthoic acids: unusual formation of the carboxylic acid dimer in the presence of a heterosynthon
    Dejan Kresimir Bucar
    Solid State Sciences, Global Pharmaceutical R and D, Abbott Laboratories, North Chicago, Illinois 60064, USA
    Mol Pharm 4:339-46. 2007
    ..In the case of 6-hydroxy-2-naphthoic acid, the co-crystal exhibits a hydrogen-bonded carboxylic acid dimer in the presence of a hydroxyl-caffeine heterosynthon...
  38. ncbi Development of spray-dried co-precipitate of amorphous celecoxib containing storage and compression stabilizers
    Ravindra S Dhumal
    Department of Pharmaceutics, Bharati Vidyapeeth University, Poona College of Pharmacy and Research Centre, Erandawane, Pune 411038 Maharashtra, India
    Acta Pharm 57:287-300. 2007
    ..The present study demonstrates the synergistic effect of combining two types of stabilizers, PVP and CAR, on the stability of amorphous drug during compression and storage as compared to their effect when used alone...
  39. ncbi Comparative physicochemical characterization of phospholipids complex of puerarin formulated by conventional and supercritical methods
    Ying Li
    Shanghai Jiao Tong University, Shanghai, PR China
    Pharm Res 25:563-77. 2008
    ..The physicochemical properties of the pure drug and the corresponding products prepared by two different SCF methods were also compared...
  40. ncbi Supramolecular medicinal chemistry: mixed-ligand coordination complexes
    Zhenbo Ma
    Department of Chemistry, Brown University, 324 Brook Street, Providence, Rhode Island 02912, USA
    Mol Pharm 4:373-85. 2007
    ....
  41. ncbi Characterization and relevance of physicochemical interactions among components of a novel multiparticulate formulation for colonic delivery
    Brahma N Singh
    Drug Delivery Systems Research Laboratory, College of Pharmacy and Allied Health Professions, St John s University, 8000 Utopia Parkway, Jamaica, NY 11439, USA
    Int J Pharm 341:143-51. 2007
    ..The formation of AZA-Ca(2+) complex could have an impact on drug release kinetics, product stability and clinical efficacy for treatment of inflammatory bowel diseases or other diseases, which merit further investigation...
  42. ncbi Crystal growth formation in melt extrudates
    Caroline Bruce
    College of Pharmacy, The University of Texas, Austin, TX 78712, United States
    Int J Pharm 341:162-72. 2007
    ..In vitro drug release studies showed no significant change during storage for up to 6 months at 25 degrees C/60% relative humidity and 40 degrees C/75% relative humidity...
  43. ncbi Application of direct crystallization for racemic compound propranolol hydrochloride
    Xiujuan Wang
    Division of Chemical and Biomolecular Engineering, Nanyang Technological University of Singapore, Innovation Centre, Block 1, 16 Nanyang Drive, Singapore
    J Pharm Sci 96:2735-45. 2007
    ..Hence, the critical supersaturation control of a solution was essential to obtain pure enantiomers from a partially resolved racemate...
  44. ncbi Structural study of polymorphs and solvates of finasteride
    Abdullah Othman
    Department of Chemistry, University of Durham, South Road, Durham DH1 3LE, UK
    J Pharm Sci 96:1380-97. 2007
    ..Mobility of the tert-butyl group is also implied. Thermal characteristics have been studied and TGA used (in conjunction with solution-state proton NMR) to estimate molar ratios...
  45. ncbi Assessment of defects and amorphous structure produced in raffinose pentahydrate upon dehydration
    Simon Bates
    SSCI, Inc, West Lafayette, Indiana 47906, USA
    J Pharm Sci 96:1418-33. 2007
    ..amorphous form by dehydration at 60 degrees C, well below its melting temperature, was monitored by X-ray powder diffraction over a period of 72 h...
  46. ncbi Polymorphism of linezolid: a combined single-crystal, powder diffraction and NMR study
    Elisabetta Maccaroni
    Dipartimento di Scienze Chimiche e Ambientali, Universita dell Insubria, Via Valleggio 11, I 22100 Como, Italy
    Int J Pharm 351:144-51. 2008
    ..1(3)A3, Z=4, Z'=1), while powders of form IV could be fully characterized by employing ab initio powder diffraction methods (triclinic, P1, a=6.5952(7)A, b=10.9875(10)A, c=12.9189(14)A, alpha=110.683(4) degrees , beta=88...
  47. ncbi Crystallographic characterization of several erythromycin A solvates: the environment of the solvent molecules in the crystal lattice
    Rodger Henry
    Structural Chemistry, Global Pharmaceutical R and D, Abbott Laboratories, 100 Abbott Park Rd, Abbott Park, Illinois 60064, USA
    J Pharm Sci 96:1251-7. 2007
    ..The isopropanol solvate exhibits uncommon modes of hydrogen bonding, which have previously been seen only in the erythomycin B hydrate. The methanol solvate is strikingly similar to the methanol solvate of 6-O-methyl erythromycin...
  48. ncbi Enhanced efficiency of direct-space structure solution from powder X-ray diffraction data in the case of conformationally flexible molecules
    Andrew J Hanson
    School of Chemistry, Cardiff University, Park Place, Cardiff, CF10 3AT Wales, UK
    J Phys Chem B 111:6349-56. 2007
    ..The strategy is shown to lead to significant improvements in the success rate of structure-solution calculations in the case of flexible molecules with a significant number of conformational degrees of freedom...
  49. ncbi Formulation of spray-dried phenytoin loaded poly(epsilon-caprolactone) microcarrier intended for brain delivery to treat epilepsy
    Zhuzhu Li
    Division of Pharmaceutical Sciences, University of Missouri Kansas City, 5005 Rockhill Road, Kansas City, Missouri 64110 2499, USA
    J Pharm Sci 96:1018-30. 2007
    ..These data suggested that PHT containing spray-dried PCL-microcarrier may be a promising drug delivery system for local brain delivery and long-term treatment of pharmacoresistant epilepsy...
  50. ncbi Physical characterization of component particles included in dry powder inhalers. I. Strategy review and static characteristics
    Anthony J Hickey
    Division of Molecular Pharmaceutics, School of Pharmacy, University of North Carolina, Campus Box 7360, 1310 Kerr Hall, Kerr Hall, Chapel Hill, North Carolina 27599 7360, USA
    J Pharm Sci 96:1282-301. 2007
    ..This is the first of two papers that discuss static and dynamic methods of characterizing dry powder inhaler formulations...
  51. ncbi Demonstration of a shear-based solid-state phase transformation in a small molecular organic system: chlorpropamide
    Peter L D Wildfong
    Duquesne University Mylan School of Pharmacy, 600 Forbes Avenue, Pittsburgh, Pennsylvania 15282, USA
    J Pharm Sci 96:1100-13. 2007
    ..It is suggested that the transformation of either form is allowed when resolved shear stresses initiate deformation, causing lattice distortion, which allows the simultaneous reconformation of molecules...
  52. ncbi Solving molecular crystal structures from X-ray powder diffraction data: the challenges posed by gamma-carbamazepine and chlorothiazide N,N,-dimethylformamide (1/2) solvate
    Philippe Fernandes
    Solid State Research Group, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 27 Taylor Street, Glasgow G4 0NR, UK
    J Pharm Sci 96:1192-202. 2007
    ..solvate (1/2) (P2(1)/c, Z' = 2) have been determined from synchrotron and laboratory X-ray powder diffraction data, respectively, using simulated annealing...
  53. ncbi Polymorphism of Alprazolam (Xanax): a review of its crystalline phases and identification, crystallographic characterization, and crystal structure of a new polymorph (form III)
    Hector Novoa de Armas
    Laboratory for Biocrystallography Formely Laboratorium voor Analytische Chemie en Medicinale Fysicochemie, Katholieke Universiteit Leuven, Faculty of Pharmaceutical Sciences, O and N2 Campus Gasthuisberg, Leuven, Belgium
    J Pharm Sci 96:1114-30. 2007
    ..C(17)H(13)ClN(4), has been investigated by means of X-ray powder diffraction (XRPD), single crystal X-ray diffraction, and differential scanning calorimetry (DSC)...
  54. ncbi Crystallization pathways and kinetics of carbamazepine-nicotinamide cocrystals from the amorphous state by in situ thermomicroscopy, spectroscopy, and calorimetry studies
    K Seefeldt
    Department of Pharmaceutical Sciences, 428 Church St University of Michigan, Ann Arbor, Michigan 48109 1065, USA
    J Pharm Sci 96:1147-58. 2007
    ..microscopy (HSPM), hot-stage Raman microscopy (HSRM), differential scanning calorimetry (DSC), and X-ray powder diffraction (XRPD)...
  55. ncbi Indomethacin-saccharin cocrystal: design, synthesis and preliminary pharmaceutical characterization
    Srinivas Basavoju
    Department of Health Science, Lulea University of Technology, Lulea, S 971 87, Sweden
    Pharm Res 25:530-41. 2008
    ..To design and prepare cocrystals of indomethacin using crystal engineering approaches, with the ultimate objective of improving the physical properties of indomethacin, especially solubility and dissolution rate...
  56. pmc Preparation and evaluation of taste masked famotidine formulation using drug/beta-cyclodextrin/polymer ternary complexation approach
    Ashok R Patel
    Centre for Novel Drug Delivery Systems, Department of Pharmaceutical Sciences, University Institute of Chemical Technology, Matunga, Mumbai 400019, India
    AAPS PharmSciTech 9:544-50. 2008
    ..In conclusion, the study confirmed that ternary complexation can be utilized as an alternative approach for effective taste masking...
  57. pmc Development and characterization of zaleplon solid dispersion systems: a technical note
    Atish Waghmare
    Department of Pharmaceutical Chemistry, Government College of Pharmacy, Karad, Maharashtra 415124, India
    AAPS PharmSciTech 9:536-43. 2008
  58. ncbi Preparation, characterization and in vitro cytotoxicity of indomethacin-loaded PLLA/PLGA microparticles using supercritical CO2 technique
    Yunqing Kang
    College of Materials Science and Engineering, Sichuan University, 29 Wangjiang Road, Chengdu, PR China
    Eur J Pharm Biopharm 70:85-97. 2008
    ..These results collectively suggested that IDMC-PLLA/PLGA microparticles prepared using SEDS would have potentials in anti-tumor applications as a controlled drug release dosage form without harmful organic solvent residue...
  59. ncbi The influence of thermal and mechanical preparative techniques on the amorphous state of four poorly soluble compounds
    James E Patterson
    School of Pharmacy, University of Otago, PO Box 913, 9001 Dunedin, New Zealand
    J Pharm Sci 94:1998-2012. 2005
    ..Ball milling may also be of use as a preparative technique however its effectiveness is dependent on the unit cell structure of the compound...
  60. ncbi Modulation of microenvironmental pH and crystallinity of ionizable telmisartan using alkalizers in solid dispersions for controlled release
    Phuong Ha Lien Tran
    National Research Lab for Bioavailability Control, College of Pharmacy, Kangwon National University, Chuncheon, Republic of Korea
    J Control Release 129:59-65. 2008
    ..It was evident that the alkalizers in PEG 6000 based SDs synergistically enhanced dissolution of TEL not only by modulating pH(M) but also by changing drug crystallinity to an amorphous form via molecular interactions...
  61. ncbi Single crystal and powder diffraction characterization of three polymorphic forms of Acitretin
    Luciana Malpezzi
    Dipartimento di Chimica, Materiali ed Ingegneria Chimica G Natta, Politecnico di Milano, Via Mancinelli, 20131, Milano, Italy
    J Pharm Sci 94:1067-78. 2005
    ..the crystal structures of which have been determined by single-crystal diffractometry (form I) or X-ray powder diffraction methods (form II and III) from conventional laboratory data only...
  62. ncbi Preparation of amorphous cefuroxime axetil nanoparticles by sonoprecipitation for enhancement of bioavailability
    Ravindra S Dhumal
    Department of Pharmaceutics, Poona College of Pharmacy and Research Centre, Bharati Vidyapeeth University, Erandawane, Pune, Maharashtra, India
    Eur J Pharm Biopharm 70:109-15. 2008
    ....
  63. ncbi Controlled poorly soluble drug release from solid self-microemulsifying formulations with high viscosity hydroxypropylmethylcellulose
    Tao Yi
    College of Life Science and Technology, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan 430074, China
    Eur J Pharm Sci 34:274-80. 2008
    ..microscopy (TEM), scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and X-ray powder diffraction, differences were found in the particle structure between both types of formulations...
  64. ncbi High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids
    Sherry L Morissette
    TransForm Pharmaceuticals, Inc, 29 Hartwell Avenue, Lexington, MA 02421, USA
    Adv Drug Deliv Rev 56:275-300. 2004
    ..This review highlights the opportunities and challenges of HT crystallization technologies as they apply to pharmaceutical research and development...
  65. ncbi Preparation and characterization of glassy celecoxib
    A R Paradkar
    Department of Pharmaceutics, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Erandwane, Pune, Maharashtra State, India
    Drug Dev Ind Pharm 29:739-44. 2003
    ..celecoxib were studied using infrared (IR) spectroscopy, differential scanning calorimetry (DSC), X-ray powder diffraction (XRPD), intrinsic dissolution rate (IDR), and thin-layer-chromatography (TLC)...
  66. pmc Design and optimization of mefloquine hydrochloride microparticles for bitter taste masking
    Punit P Shah
    Center of Relevance and Excellence in NDDS, Pharmacy Department, The M S University of Baroda, G H Patel building, Donor s Plaza, Fatehgunj, Vadodara, Gujarat, India
    AAPS PharmSciTech 9:377-89. 2008
    ..The bitterness score of microparticles was decreased to zero compared to 3+ of pure ARM. In conclusion the bitterness of MFL was reduced with improved dissolution at acidic pH...
  67. ncbi Solid state and dissolution rate characterization of co-ground mixtures of nifedipine and hydrophilic carriers
    H Friedrich
    College of Pharmacy, Freie Universitat Berlin, Kelchstrasse 31, Berlin, Germany
    Drug Dev Ind Pharm 31:719-28. 2005
    ..Differential scanning calorimetry (DSC) measurements gave valuable information about the nature of drug crystallinity and the interactions with the carriers within the ground mixtures...
  68. ncbi The physicochemical characteristics of freeze-dried scutellarin-cyclodextrin tetracomponent complexes
    Feng Cao
    Department of Pharmaceutics, China Pharmaceutical University, Nanjing, P R China
    Drug Dev Ind Pharm 31:747-56. 2005
    ..65 mg/ml) was achieved with tetracomponent freeze-dried complex, up to 148-fold increase over scutellarin solubility in water, and the solubility of scutellarin is 15.35 microg/ml (up to 6-fold) in simulated gastric fluid...
  69. ncbi Structure determination of enalapril maleate form II from high-resolution X-ray powder diffraction data
    Y H Kiang
    Merck Research Laboratories, Merck and Co, Inc, PO Box 4, West Point, Pennsylvania, 19426, USA
    J Pharm Sci 92:1844-53. 2003
    ..Lattice energy calculation showed that Form II is slightly more stable than Form I by 3.5 kcal/mole...
  70. ncbi Fibrous red phosphorus
    Michael Ruck
    Institut fur Anorganische Chemie, Technische Universitat Dresden, 01062 Dresden, Germany
    Angew Chem Int Ed Engl 44:7616-9. 2005
  71. ncbi Development of fast-dissolving tablets of flurbiprofen-cyclodextrin complexes
    Marzia Cirri
    Dipartimento di Scienze Farmaceutiche, Universita di Firenze, Polo Scientifico di Sesto Fiorentino, Sesto Fiorentino, Firenze, Italy
    Drug Dev Ind Pharm 31:697-707. 2005
    ..Finally, it can be reasonably expected that the obtained drug dissolution rate improvement will result in an increase of its bioavailability, with the possibility of reducing drug dosage and side effects...
  72. ncbi Physical-chemical characterization and polymorphism determination of two nimodipine samples deriving from distinct laboratories
    Te├│filo Mazon Cardoso
    Departamento de Ciencias Farmaceuticas, Universidade Federal de Santa Catarina, Florianopolis, SC, Brazil
    Drug Dev Ind Pharm 31:631-7. 2005
    ..shape, size, and crystallinity of particles were visualized by scanning electron microscopy (SEM) and X-ray powder diffraction. To sum up, the techniques used in this study can be said to have been efficient in the characterization and ..
  73. ncbi Interconversion studies of betamethasone acetate polymorphs
    Xue Ke
    Department of Pharmaceutics, China Pharmaceutical University, Nanjing, P R of China
    Drug Dev Ind Pharm 31:813-8. 2005
    ..and suspending in water, based on differential scanning calorimetry, thermogravimetric analysis, and X-ray powder diffraction. There existed enantiotropic relationships between the three polymorphs of BA, which were named form II, ..
  74. pmc Development and evaluation of artemether taste masked rapid disintegrating tablets with improved dissolution using solid dispersion technique
    Punit P Shah
    Center of Relevance and Excellence in NDDS, Pharmacy Department, The M S University of Baroda, G H Patel building, Donor s Plaza, Fatehgunj, Vadodara, Gujarat 390002, India
    AAPS PharmSciTech 9:494-500. 2008
    ..Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), and X-ray powder diffraction (XRPD) were performed to identify the physicochemical interaction between drug and carrier, hence its effect ..
  75. ncbi Physical stability and solubility of the thermotropic mesophase of fenoprofen calcium as pure drug and in a tablet formulation
    James Patterson
    Solid State Research Group, School of Pharmacy, University of Otago, Dunedin, New Zealand
    Int J Pharm 247:147-57. 2002
    ..forms of fenoprofen calcium could be differentiated by diffuse reflectance infra-red spectroscopy and X-ray powder diffraction, both as pure drug and in tablet formulation...
  76. ncbi Urea Route to Homoleptic Cyanates-Characterization and Luminescence Properties of [M(OCN)(2)(urea)] and M(OCN)(2) with M=Sr, Eu
    Sandro Pagano
    , Department Chemie und Biochemie, Butenandtstrasse 5 13 D, , Fax 49 89 2180 77440
    Chemistry 15:6186-93. 2009
    ..The crystal structures of Sr(OCN)(2) and Eu(OCN)(2) were determined from X-ray powder diffraction data and refined by the Rietveld method...
  77. ncbi Polymorphism of microcrystalline urate oxidase from Aspergillus flavus
    Ines Collings
    European Synchrotron Radiation Facility, BP 220, F 38043 Grenoble Cedex 9, France
    Acta Crystallogr D Biol Crystallogr 66:539-48. 2010
    ..The related crystalline phases were characterized by means of high-resolution synchrotron X-ray powder diffraction. In all cases, Uox complexed with the inhibitor 8-azaxanthine (AZA) was not altered from its robust ..
  78. ncbi Characterization of dehydration behavior of untreated and pulverized creatine monohydrate powders
    Yukoh Sakata
    Healthcare Research Institute, Wakunaga Pharmaceutical Co, Ltd, 1624 Shimokotachi, Kodacho, Takatagun, Hiroshima 739 1195, Japan
    Colloids Surf B Biointerfaces 35:185-91. 2004
    ..The removal of crystal water was investigated by using differential scanning calorimetry (DSC), X-ray powder diffraction and scanning electron microscopy (SEM)...
  79. ncbi Lanthanide oleates: chelation, self-assembly, and exemplification of ordered nanostructured colloidal contrast agents for medical imaging
    Guozhen Liu
    CSIRO Molecular and Health Technologies CMHT, Private Bag 10, Clayton South MDC, VIC 3169, Australia
    J Phys Chem B 113:15949-59. 2009
    ..oleates have been studied by elemental analysis, Fourier transfer infrared spectroscopy (FTIR), and X-ray powder diffraction (XRD) analysis...
  80. ncbi Microcrystalline cellulose, a useful alternative for sucrose as a matrix former during freeze-drying of drug nanosuspensions - a case study with itraconazole
    Bernard Van Eerdenbrugh
    Laboratory for Pharmacotechnology and Biopharmacy, Leuven, Belgium
    Eur J Pharm Biopharm 70:590-6. 2008
    ..The crystalline itraconazole nanoparticles showed peak broadening in the X-ray powder diffraction spectra and a lower melting point as inferred from differential scanning calorimetry...
  81. ncbi Visible-light-induced photocatalysis through surface plasmon excitation of gold on titania surfaces
    Ewa Kowalska
    Catalysis Research Center, Hokkaido University, North 21, West 10, Sapporo 001 0021, Japan
    Phys Chem Chem Phys 12:2344-55. 2010
    ..field-emission scanning electron microscopy (FE-SEM), scanning transmission microscopy (STEM) and X-ray powder diffraction (XRD)...
  82. ncbi Enhanced solubility and bioavailability of sibutramine base by solid dispersion system with aqueous medium
    Dong Xun Li
    College of Pharmacy, Yeungnam University, 214 1 Dae Dong, Gyongsan 712 749, South Korea
    Biol Pharm Bull 33:279-84. 2010
    ..investigated using scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and X-ray powder diffraction. The dissolution and pharmacokinetics in rats of solid dispersion were evaluated compared to the sibutramine ..
  83. ncbi Structure and solid-state chemistry of anhydrous and hydrated crystal forms of the trimethoprim-sulfamethoxypyridazine 1:1 molecular complex
    G Bettinetti
    Dipartimento di Chimica Farmaceutica, Universita di Pavia, Viale Taramelli 12, I 27100 Pavia, Italy
    J Pharm Sci 89:478-89. 2000
    ..5 molecules of water of crystallization (TMP.SMPD.W) are reported in this article. X-ray powder diffraction patterns (both computer generated and experimental) and thermal analytical data from differential scanning ..
  84. ncbi Coordination chemistry of mercury(II) in liquid and aqueous ammonia solution and the crystal structure of tetraamminemercury(II) perchlorate
    Kersti B Nilsson
    Department of Chemistry, Swedish University of Agricultural Sciences, PO Box 7015, SE 750 07 Uppsala, Sweden
    Inorg Chem 47:1953-64. 2008
    ..199)Hg NMR, and Raman spectroscopy and in solid solvates by combining results from X-ray single crystal and powder diffraction, thermogravimetry, differential scanning calorimetry, EXAFS, and Raman spectroscopy...
  85. ncbi Rapid assessment of the structural relaxation behavior of amorphous pharmaceutical solids: effect of residual water on molecular mobility
    Danforth P Miller
    Nektar Therapeutics, 150 Industrial Road, San Carlos, California 94070, USA
    Pharm Res 23:2291-305. 2006
    ....
  86. ncbi Characterisation of products of tricalcium silicate hydration in the presence of heavy metals
    Q Y Chen
    School of Environmental Science and Engineering, Donghua University, Shanghai 200051, PR China
    J Hazard Mater 147:817-25. 2007
    ..doped with nitrate salts of Zn(2+), Pb(2+), Cu(2+) and Cr(3+) were examined at different ages by X-ray powder diffraction (XRD), thermal analysis (DTA/TG) and (29)Si solid-state magic angle spinning/nuclear magnetic resonance (MAS/..
  87. ncbi Direct electrochemistry and electrocatalysis of horseradish peroxidase in alpha-zirconium phosphate nanosheet film
    Xiushuang Yang
    State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China
    Bioelectrochemistry 74:90-5. 2008
    ..X-ray powder diffraction (XRD) results revealed that ZrPNS in HRP-ZrPNS film remained unorderly structured for the effect of HRP...
  88. ncbi Foreign material as a cause of choledocholithiasis
    V Prochazka
    2nd Internal Clinic, Palacky University, Olomouc, Czech Republic
    Endoscopy 31:383-5. 1999
    ..Gallstones obtained endoscopically from the biliary duct were analyzed to determine their structure and the presence of foreign material. The possible correlation between foreign material in gallstones and clinical data was investigated...
  89. ncbi Microcalorimetric measurement of the interactions between water vapor and amorphous pharmaceutical solids
    David Lechuga-Ballesteros
    Nektar Therapeutics formerly Inhale Therapeutics Systems, Inc, 150 Industrial Road, San Carlos, California 94070, USA
    Pharm Res 20:308-18. 2003
    ....
  90. ncbi Hydrogarnet: a host phase for Cr(VI) in chromite ore processing residue (COPR) and other high pH wastes
    S Hillier
    Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
    Environ Sci Technol 41:1921-7. 2007
    ..X-ray powder diffraction data show that peak intensities are altered by chromium substitution and that chromium substituted ..
  91. ncbi Novel three-dimensional pillared-layer Ln(III)-Cu(I) coordination polymers featuring spindle-shaped heterometallic building units
    Qi Bing Bo
    School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China
    Inorg Chem 49:561-71. 2010
    ..thermogravimetry-differential thermal analysis (TG-DTA), single-crystal X-ray diffraction, X-ray powder diffraction (XRPD), and nitrogen adsorption/desorption techniques...
  92. ncbi Immobilization of lead in shooting range soils by means of cement, quicklime, and phosphate amendments
    Xinde Cao
    Center for Environmental Systems, Stevens Institute of Technology, Hoboken, NJ 07030, USA
    Environ Sci Pollut Res Int 15:120-7. 2008
    ..This study investigated stabilization of Pb in shooting range soils treated with cement, quicklime, and phosphate...
  93. ncbi Implications of organic matter on arsenic mobilization into groundwater: evidence from northwestern (Chapai-Nawabganj), central (Manikganj) and southeastern (Chandpur) Bangladesh
    A H M Selim Reza
    Department of Earth Sciences, National Cheng Kung University, Tainan 70101, Taiwan
    Water Res 44:5556-74. 2010
    ..X-ray powder diffraction (XRD) and X-ray fluorescence (XRF) were performed to characterize the major mineral and chemical contents of ..
  94. pmc Effects of spray drying on physicochemical properties of chitosan acid salts
    Mirna Fernández Cervera
    Institute of Pharmacy and Food, University of Havana, La Coronela, La Lisa, Cuba
    AAPS PharmSciTech 12:637-49. 2011
    ..salts were investigated by means of solid-state CP-MAS (13)C nuclear magnetic resonance (NMR), X-ray powder diffraction (XRPD), differential scanning calorimetry, and Fourier transform infrared spectrometry (FTIR) and near-..
  95. ncbi Design and synthesis of vanadium hydrazide gels for Kubas-type hydrogen adsorption: a new class of hydrogen storage materials
    Tuan K A Hoang
    Department of Chemistry and Biochemistry, University of Windsor, 401 Sunset Avenue, Windsor, Ontario N9B 3P4, Canada
    J Am Chem Soc 132:11792-8. 2010
    ..5, and 1:2 and characterized by X-ray powder diffraction, X-ray photoelectron spectroscopy, nitrogen adsorption, elemental analysis, infrared spectroscopy, and ..
  96. ncbi Synthesis and crystal structure from X-ray powder diffraction data of two zirconium diphosphonates containing piperazine groups
    Marco Taddei
    Department of Chemistry, University of Perugia, Via Elce di Sotto 8, 06123 Perugia, Italy
    Inorg Chem 49:9664-70. 2010
    ..Their crystal structure has been determined ab initio from X-ray powder diffraction data collected with a conventional diffractometer...
  97. ncbi Hydration of microcrystalline cellulose and milled cellulose studied by sorption calorimetry
    Vitaly Kocherbitov
    Biomedical Laboratory Science and Technology, Faculty of Health and Society, Malmo University, SE 205 06 Malmo, Sweden
    J Phys Chem B 112:3728-34. 2008
    ..was studied using water sorption calorimetry, gravimetric water vapor sorption, nitrogen sorption, and X-ray powder diffraction. Amorphous cellulose was prepared by means of ball-milling of microcrystalline cellulose (MCC)...
  98. ncbi Optimization of a pharmaceutical freeze-dried product and its process using an experimental design approach and innovative process analyzers
    T R M De Beer
    Department of Pharmaceutical Analysis, Ghent University, Gent, Belgium
    Talanta 83:1623-33. 2011
    ..Off-line X-ray powder diffraction analysis and Karl-Fisher titration were performed to determine the morphology and residual moisture content ..
  99. ncbi Itraconazole/TPGS/Aerosil200 solid dispersions: characterization, physical stability and in vivo performance
    Bernard Van Eerdenbrugh
    Laboratory for Pharmacotechnology and Biopharmacy, K U Leuven, Gasthuisberg O and N2, Herestraat 49, box 921, 3000 Leuven, Belgium
    Eur J Pharm Sci 38:270-8. 2009
    ..3% and 7.8%. X-ray powder diffraction (XRPD), solid state NMR (SSNMR) and differential scanning calorimetry (DSC) evaluation on the powders ..
  100. ncbi Crystal chemistry of sodium zirconium phosphate based simulated ceramic waste forms of effluent cations (Ba(2+), Sn(4+), Fe(3+), Cr(3+), Ni(2+) and Si(4+)) from light water reactor fuel reprocessing plants
    O P Shrivastava
    Department of Chemistry, Dr HS Gour University, Sagar, India
    J Hazard Mater 153:285-92. 2008
    ..14)O(12)) has been investigated using General Structure Analysis System (GSAS) programming of the X-ray powder diffraction data...
  101. ncbi Metastable Se6 as a ligand for Ag+: from isolated molecular to polymeric 1D and 2D structures
    Damian Aris
    Department of Chemistry, University of New Brunswick, Fredericton N B, E3B 6E2, Canada
    Dalton Trans 40:5865-80. 2011
    ..X-ray structure determinations, 2b and 4 additionally by chemical analysis and 4 also by X-ray powder diffraction, FT-Raman and FT-IR spectroscopy...

Research Grants10

  1. CARBON-13 MAGNETIC RESONANCE - METHODS AND THEORY
    DAVID MORRIS GRANT; Fiscal Year: 2010
    ..This allows x-ray powder diffraction (XRPD) to be combined with SSNMR in obtaining lattice structure...
  2. STRUCTURAL CHEMICAL STUDIES OF METABOLIC PHOSPHATES
    Robert Blessing; Fiscal Year: 1992
    ..electron crystallography for unit cell and space group determination, state- of-the-art methods of X-ray powder diffraction for structure determination and refinement, time-of-flight neutron diffraction with powder samples and a ..
  3. Strutural basis of amyloid fiber pathology
    Ruben Diaz Avalos; Fiscal Year: 2003
    ..5 Angstrom units resolution will be correlated with X-ray powder diffraction data to determine the atomic structure of the tightly-paired, water-excluding cross-beta peptide chains in ..
  4. 1-D Silicon Detector for Synchrotron XRD
    CAROLYN TULL; Fiscal Year: 2004
    ..detector, and the accompanying integrated circuit pulse-processing electronics, for high-speed synchrotron powder diffraction experiments...
  5. X-RAY DIFFRACTION SUPPORT UNDERGRADUATE RESEARCH
    Edward Valente; Fiscal Year: 1990
    ..isotherms with spectroscopy, and crystals will be studied by ft-ir spectroscopy and single crystal and powder diffraction methods...
  6. Sol-Gel Synthesis of bioactive glass materials
    Aderemi Oki; Fiscal Year: 2003
    ..Zinc compound has also been shown to reveal a stimulatory effect on differentiation of osteoblastic cells. ..
  7. Structural analysis of the hepatitis C core protein
    Marc Allaire; Fiscal Year: 2005
    ..Altogether, the determination of the structure of the capsid will facilitate the development of research programs that aim to inhibit the assembly of the virus, a novel and very promising target for drug development. ..
  8. MECHANISMS OF RESPONSE TO PULMONARY VACCINATION
    Anthony Hickey; Fiscal Year: 2005
    ..The significance of this work lies in the novelty of pulmonary vaccination for the treatment of tuberculosis and the knowledge of the immune response gained from targeted antigen delivery to the lungs. ..
  9. Metals and Protein Structure in Protein-Folding Diseases
    Lisa Miller; Fiscal Year: 2007
    ..Finally, we use the local structure and homogeneity of the in situ metal-protein complex to develop a possible mechanism for the complex formation and toxicity. ..
  10. Synchrotron-Based Infrared Microscope for Chemical Imaging of Disease
    Lisa Miller; Fiscal Year: 2007
    ..This instrument will be unique worldwide. [unreadable] [unreadable] [unreadable]..