surgical flaps

Summary

Summary: Tongues of tissue (skin and subcutaneous tissue, sometimes including muscle) cut away from the underlying parts but attached at one end. They retain their own blood supply during transfer to the new site. They are used in plastic surgery for filling a defect in a neighboring region. The concept includes pedicled flaps, rotation flaps, tube flaps, etc.

Top Publications

  1. ncbi Pectoralis major myocutaneous flap vs revascularized free tissue transfer: complications, gastrostomy tube dependence, and hospitalization
    Douglas B Chepeha
    Department of Otolaryngology Head and Neck Surgery, University of Michigan, Ann Arbor 48109 0312, USA
    Arch Otolaryngol Head Neck Surg 130:181-6. 2004
  2. ncbi Endoscopic skull base reconstruction of large dural defects: a systematic review of published evidence
    Richard J Harvey
    Department of Otolaryngology and Skull Base Surgery, St Vincent s Hospital, Sydney, New South Wales, Australia
    Laryngoscope 122:452-9. 2012
  3. ncbi Pectoralis major myocutaneous flaps for head and neck reconstruction: factors influencing occurrences of complications and the final outcome
    Fábio Roberto Pinto
    FMABC, Sao Bernardo do Campo, Sao Paulo, Brazil
    Sao Paulo Med J 128:336-41. 2010
  4. ncbi Comparison of the IntraLase femtosecond laser and mechanical keratomes for laser in situ keratomileusis
    Guy M Kezirian
    Southeastern Eye Center, Greensboro, NC, USA
    J Cataract Refract Surg 30:804-11. 2004
  5. ncbi Improved viability of random pattern skin flaps through the use of adipose-derived stem cells
    Feng Lu
    Department of Plastic and Reconstructive Surgery, Nippon Medical School, Tokyo, Japan
    Plast Reconstr Surg 121:50-8. 2008
  6. ncbi Comparison of the radial forearm flap and the thinned anterolateral thigh cutaneous flap for reconstruction of tongue defects: an evaluation of donor-site morbidity
    Chih Hung Huang
    Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan
    Plast Reconstr Surg 114:1704-10. 2004
  7. ncbi Analysis of the relations between the shape of the reconstructed tongue and postoperative functions after subtotal or total glossectomy
    Yoshihiro Kimata
    Division of Plastic and Reconstructive Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
    Laryngoscope 113:905-9. 2003
  8. ncbi A novel reconstructive technique after endoscopic expanded endonasal approaches: vascular pedicle nasoseptal flap
    Gustavo Hadad
    Department of Otolaryngology Head and Neck Surgery, Medical School of Ciudad de Rosario, Provincia de Santa Fe, Republica Argentina
    Laryngoscope 116:1882-6. 2006
  9. pmc Effect of femtosecond laser energy level on corneal stromal cell death and inflammation
    Fabricio Witzel de Medeiros
    Cleveland Clinic, Cole Eye Institute, Ohio 44195, USA
    J Refract Surg 25:869-74. 2009
  10. ncbi Reconstruction of the mandible with osseous free flaps: a 10-year experience with 150 consecutive patients
    P G Cordeiro
    Plastic and Reconstructive Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Plast Reconstr Surg 104:1314-20. 1999

Research Grants

  1. Assessment of Reconstructive Surgical Flaps Using Spatially Resolved Tissue Oxima
    Anthony J Durkin; Fiscal Year: 2012
  2. Sustained Regeneration of Soft Tissue Defects
    Jonathan Kluge; Fiscal Year: 2012
  3. Molecular Heparan Sulfate Delivery in Guided Tissue Regeneration
    Arthur DeCarlo; Fiscal Year: 2007
  4. EFFECTS OF TREATMENT ON EARLY ONSET PERIODONTITIS
    Frank Roberts; Fiscal Year: 2003
  5. Microarray Analysis of Wounds
    AMY COLWELL; Fiscal Year: 2004
  6. Bone Marrow Stromal Cells for Bladder Tissue Engineering
    Yuanyuan Zhang; Fiscal Year: 2006
  7. COLLABORATIVE INITIAL GLAUCOMA TREATMENT STUDY
    Henry Jampel; Fiscal Year: 2002
  8. EARLY DETECTION OF GLAUCOMA DAMAGE
    Henry Jampel; Fiscal Year: 2004
  9. GLAUCOMA SURGICAL OUTCOMES STUDY
    Henry Jampel; Fiscal Year: 2001
  10. IN VIVO MECHANISMS OF LOCAL STATIN-INDUCED BONE
    Richard Reinhardt; Fiscal Year: 2004

Detail Information

Publications292 found, 100 shown here

  1. ncbi Pectoralis major myocutaneous flap vs revascularized free tissue transfer: complications, gastrostomy tube dependence, and hospitalization
    Douglas B Chepeha
    Department of Otolaryngology Head and Neck Surgery, University of Michigan, Ann Arbor 48109 0312, USA
    Arch Otolaryngol Head Neck Surg 130:181-6. 2004
    ..To evaluate the factors related to surgical complications, rate of gastrostomy tube (G-tube) dependence, and hospitalization in patients undergoing reconstruction with a pectoralis myocutaneous flap vs a soft-tissue revascularized flap...
  2. ncbi Endoscopic skull base reconstruction of large dural defects: a systematic review of published evidence
    Richard J Harvey
    Department of Otolaryngology and Skull Base Surgery, St Vincent s Hospital, Sydney, New South Wales, Australia
    Laryngoscope 122:452-9. 2012
    ..Such surgical innovation is likely to be reported in case series, retrospective cohorts, or case-control studies rather than higher level evidence...
  3. ncbi Pectoralis major myocutaneous flaps for head and neck reconstruction: factors influencing occurrences of complications and the final outcome
    Fábio Roberto Pinto
    FMABC, Sao Bernardo do Campo, Sao Paulo, Brazil
    Sao Paulo Med J 128:336-41. 2010
    ..The aim of this study was to identify factors that may cause complications and influence the final result from reconstructions using pectoralis major myocutaneous flaps (PMMFs) for head and neck defect repair following cancer resection...
  4. ncbi Comparison of the IntraLase femtosecond laser and mechanical keratomes for laser in situ keratomileusis
    Guy M Kezirian
    Southeastern Eye Center, Greensboro, NC, USA
    J Cataract Refract Surg 30:804-11. 2004
    ..To compare laser in situ keratomileusis (LASIK) results obtained with the femtosecond laser (IntraLase Corp.) to those obtained using 2 popular mechanical microkeratomes...
  5. ncbi Improved viability of random pattern skin flaps through the use of adipose-derived stem cells
    Feng Lu
    Department of Plastic and Reconstructive Surgery, Nippon Medical School, Tokyo, Japan
    Plast Reconstr Surg 121:50-8. 2008
    ....
  6. ncbi Comparison of the radial forearm flap and the thinned anterolateral thigh cutaneous flap for reconstruction of tongue defects: an evaluation of donor-site morbidity
    Chih Hung Huang
    Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan
    Plast Reconstr Surg 114:1704-10. 2004
    ..The results achieved are similar to those of the radial forearm flap, and the donor-site morbidity is significantly decreased...
  7. ncbi Analysis of the relations between the shape of the reconstructed tongue and postoperative functions after subtotal or total glossectomy
    Yoshihiro Kimata
    Division of Plastic and Reconstructive Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
    Laryngoscope 113:905-9. 2003
    ..The objective was to investigate the relations of the shape of the reconstructed tongue to postoperative swallowing and speech functions...
  8. ncbi A novel reconstructive technique after endoscopic expanded endonasal approaches: vascular pedicle nasoseptal flap
    Gustavo Hadad
    Department of Otolaryngology Head and Neck Surgery, Medical School of Ciudad de Rosario, Provincia de Santa Fe, Republica Argentina
    Laryngoscope 116:1882-6. 2006
    ..Reconstruction with vascularized tissue is desirable to facilitate rapid healing, especially in irradiated patients...
  9. pmc Effect of femtosecond laser energy level on corneal stromal cell death and inflammation
    Fabricio Witzel de Medeiros
    Cleveland Clinic, Cole Eye Institute, Ohio 44195, USA
    J Refract Surg 25:869-74. 2009
    ..To analyze the effects of variations in femtosecond laser energy level on corneal stromal cell death and inflammatory cell influx following flap creation in a rabbit model...
  10. ncbi Reconstruction of the mandible with osseous free flaps: a 10-year experience with 150 consecutive patients
    P G Cordeiro
    Plastic and Reconstructive Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Plast Reconstr Surg 104:1314-20. 1999
    ..The ilium is recommended only when other options are unavailable. Thoughtful flap selection and design should supplant the need for multiple, simultaneous free flaps and vein grafting in most cases...
  11. ncbi Radial forearm free flap pharyngoesophageal reconstruction
    B Azizzadeh
    University of California Los Angeles School of Medicine, Los Angeles, CA 90095
    Laryngoscope 111:807-10. 2001
    ..The main disadvantage of this technique relates to a moderately high incidence of pharyngocutaneous fistulas, which contributes to delayed oral intake in affected patients...
  12. ncbi Axillary padding as an alternative to closed suction drain for ambulatory axillary lymphadenectomy: a prospective cohort of 207 patients with early breast cancer
    Jean Marc Classe
    Surgery Unit, Centre de lutte contre le cancer, Rene Gauducheau, Boulevard Jacques Monod, 44 805 Nantes Saint Herblain, France
    Arch Surg 137:169-72; discussion 173. 2002
    ..Axillary lymphadenectomy performed without the use of a drain but with padding of the axilla is feasible and safe on an outpatient basis in the setting of conservative surgery for breast cancer...
  13. ncbi Precision of flap measurements for laser in situ keratomileusis in 4428 eyes
    Gerald W Flanagan
    Gordon Binder Vision Institute, San Diego, CA, USA
    J Refract Surg 19:113-23. 2003
    ..To determine the factor(s) that influence the dimensions and predictability of the LASIK corneal flap with the Automated Corneal Shaper (ACS) or the Summit Krumeich Barraquer microkeratome (SKBM)...
  14. ncbi Effect of tobacco smoking on advancement flap repair of complex anal fistulas
    C Neal Ellis
    Department of Surgery, University of South Alabama, 2451 Fillingim St, MSTN 706, Mobile, Alabama, 36617, USA
    Dis Colon Rectum 50:459-63. 2007
    ..This study was performed to evaluate our results with advancement flap repair of anal fistulas and to identify factors associated with failure...
  15. ncbi A femtosecond laser creates a stronger flap than a mechanical microkeratome
    Jae Yong Kim
    Department of Ophthalmology and Asan Institute for Life Sciences, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Invest Ophthalmol Vis Sci 47:599-604. 2006
    ..To compare corneal flaps made with a femtosecond (FS) laser with those made with a mechanical microkeratome (MM) in rabbits, measuring early postoperative inflammation and apoptosis and late postoperative adhesion strength...
  16. ncbi Applications of the femtosecond laser in corneal refractive surgery
    Peter Kim
    Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
    Curr Opin Ophthalmol 22:238-44. 2011
    ..With the advances in femtosecond lasers, clinical outcomes and safety with their use have improved. The purpose of this review is to outline the current surgical applications of the femtosecond laser in corneal refractive surgery...
  17. pmc Femtosecond laser and microkeratome corneal flaps: comparison of stromal wound healing and inflammation
    Marcelo V Netto
    The Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Refract Surg 23:667-76. 2007
    ..To examine early postoperative wound healing in rabbit corneas that had LASIK flaps formed with three different models (15 KHz, 30 KhZ, and 60 KHz) of a femtosecond laser compared with flaps formed with a microkeratome...
  18. ncbi Microvascular reconstruction of the hypopharynx: defect classification, treatment algorithm, and functional outcome based on 165 consecutive cases
    Joseph J Disa
    Plastic Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 111:652-60; discussion 661-3. 2003
    ..Microvascular reconstruction of pharyngeal defects is highly successful with few postoperative complications. With appropriate flap selection, functional outcome can be optimized...
  19. ncbi First efficacy and safety study of femtosecond lenticule extraction for the correction of myopia: six-month results
    Walter Sekundo
    Department of Ophthalmology, Gutenberg University, Langenbeckstrasse 1, Mainz, Germany
    J Cataract Refract Surg 34:1513-20. 2008
    ..To prospectively study the feasibility of femtosecond lenticule extraction (FLE), a new method of refractive correction...
  20. ncbi Evidence-based recommendations for the use of Negative Pressure Wound Therapy in traumatic wounds and reconstructive surgery: steps towards an international consensus
    E Krug
    Leiden University Medical Centre, The Netherlands
    Injury 42:S1-12. 2011
    ..The development of evidence-based recommendations for NPWT with direct validation from a large group of practicing clinicians offers a broader basis for consensus than work by an expert panel alone...
  21. ncbi Nasoseptal flap reconstruction of high flow intraoperative cerebral spinal fluid leaks during endoscopic skull base surgery
    Adam M Zanation
    Department of Otolaryngology Head and Neck Surgery, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    Am J Rhinol Allergy 23:518-21. 2009
    ..The goals of this study are to prospectively evaluate the nasoseptal flap and high-risk cerebral spinal fluid (CSF) leak variables...
  22. ncbi Femtosecond laser-assisted corneal flap cuts: morphology, accuracy, and histopathology
    Mike P Holzer
    Heidelberg Intraocular Lenses and Refractive Surgery Research Group, Department of Ophthalmology, Ruprecht Karls University of Heidelberg, Heidelberg, Germany
    Invest Ophthalmol Vis Sci 47:2828-31. 2006
    ..In this study, we analyzed femtosecond laser flaps regarding their morphology, cut accuracy, and histopathology...
  23. ncbi Nasoseptal flap takedown and reuse in revision endoscopic skull base reconstruction
    Adam M Zanation
    Department of Otolaryngology Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Laryngoscope 121:42-6. 2011
    ....
  24. ncbi The use of muscle flaps in the salvage of infected exposed implants for internal fixation
    K J Tan
    University Orthopaedics, Hand and Reconstructive Microsurgery Cluster, National University Hospital, Young Loo Lin School of Medicine, National University of Singapore, National University Health System, 5 Lower Kent Ridge Road, Singapore
    J Bone Joint Surg Br 92:401-5. 2010
    ..The use of antibiotic beads, vacuum-assisted closure and dressing, the surgical site, the type of flap performed and the time from primary surgery to flap cover were not predictive of outcome...
  25. ncbi Comparison between free flap and pectoralis major pedicled flap for reconstruction in oral cavity cancer patients--a quality of life analysis
    Chih Yu Hsing
    Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan
    Oral Oncol 47:522-7. 2011
    ..Data from this study provide useful information for physicians and patients during their discussion of treatment modalities for oral cancers...
  26. ncbi Reconstruction of extensive defects from posterior en bloc resection of sacral tumors with human acellular dermal matrix and gluteus maximus myocutaneous flaps
    Hormuzdiyar H Dasenbrock
    School of Medicine, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Neurosurgery 69:1240-7. 2011
    ..However, reconstruction of the resultant extensive soft-tissue defects is challenging because a vertical rectus abdominis myocutaneous flap is not harvested...
  27. ncbi Reconstructive strategies for partial sacrectomy defects based on surgical outcomes
    Patrick B Garvey
    Department of Plastic Surgery, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Plast Reconstr Surg 127:190-9. 2011
    ..The purpose of this study was to determine what factors best guide selection of reconstructive techniques following partial sacrectomy to optimize outcomes...
  28. ncbi Long-term results of limberg flap procedure for treatment of pilonidal sinus: a report of 200 cases
    Koray Topgul
    Department of General Surgery, Ondokuz Mayis University School of Medicine, Samsun, Turkey
    Dis Colon Rectum 46:1545-8. 2003
    ..The most common problem in the treatment of this disease is recurrence. In the present study, our aim was to determine the long-term results of the Limberg flap procedure...
  29. ncbi A retrospective analysis of 154 arterialized venous flaps for hand reconstruction: an 11-year experience
    Sang Hyun Woo
    Kim and Woo s Institute for Hand and Reconstructive Microsurgery, Daegu Gangnam Hospital, Daegu, Korea
    Plast Reconstr Surg 119:1823-38. 2007
    ..The purpose of this study was to present the authors' 11-year clinical experience involving 154 cases of arterialized venous flaps for hand reconstruction...
  30. ncbi Flap prefabrication and prelamination with tissue-engineered cartilage
    Rainer Staudenmaier
    ENT Department, University of Regensburg Hospital, Regensburg, Germany
    J Reconstr Microsurg 20:555-64. 2004
    ....
  31. ncbi A review of the advantages of the anterolateral thigh flap in head and neck reconstruction
    Jagdeep S Chana
    Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, 199 Tung Hwa North Road, Taipei 10591, Taiwan, ROC
    Br J Plast Surg 57:603-9. 2004
  32. pmc Femtosecond laser in laser in situ keratomileusis
    Marcella Q Salomao
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Cataract Refract Surg 36:1024-32. 2010
    ..In this article, we review common considerations in management and complications of this step in femtosecond laser-LASIK and concentrate primarily on the IntraLase laser because most published studies relate to this instrument...
  33. ncbi Skin-sparing mastectomy and immediate reconstruction is an acceptable treatment option for patients with high-risk breast carcinoma
    Kevin J Downes
    Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Cancer 103:906-13. 2005
    ..Skin-sparing mastectomy (SSM) followed by immediate reconstruction is an effective treatment option for patients with early-stage breast carcinoma, but its use in patients with more advanced disease is controversial...
  34. ncbi Neovascularization and free microsurgical transfer of in vitro cartilage-engineered constructs
    Nguyen The Hoang
    Department of Hand Surgery and Microsurgery, Institute of Trauma and Orthopedics, Central University Hospital, Hanoi, Vietnam
    Microsurgery 29:52-61. 2009
    ..All constructs were well neovascularized and showed histologically stability in both size and form. Immunohistology showed the existence of cartilage-like tissue with extracellular matrix neosynthesis...
  35. ncbi Autologous breast reconstruction with the extended latissimus dorsi flap
    David W Chang
    Department of Plastic and Reconstructive Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 443, Houston, TX 77030, USA
    Plast Reconstr Surg 110:751-9; discussion 760-1. 2002
    ..In conclusion, the extended latissimus dorsi flap is a reliable method for total autologous breast reconstruction in most patients and should be considered more often as a primary choice for breast reconstruction...
  36. ncbi Implant surgery using bone- and mucosa-supported stereolithographic guides in totally edentulous jaws: surgical and post-operative outcomes of computer-aided vs. standard techniques
    Volkan Arisan
    Department of Oral Implantology, Faculty of Dentistry, Istanbul University, Capa, Istanbul, Turkey
    Clin Oral Implants Res 21:980-8. 2010
    ..The aim of this study was to compare the surgical and post-operative outcomes of a computer-aided implant surgery performed by bone- and mucosa-supported stereolithographic (SLA) guides against the standard technique...
  37. ncbi Enhancement of epigastric skin flap survival by adenovirus-mediated VEGF gene therapy
    Przemyslaw Lubiatowski
    Department of Plastic and Reconstructive Surgery, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Plast Reconstr Surg 109:1986-93. 2002
    ..9 and 48.7 percent, respectively. The results of this study raise the possibility of using adenovirus-mediated therapeutic angiogenesis for safer flap surgery in high-risk patients...
  38. ncbi Reconstruction of extensive partial or total sacrectomy defects with a transabdominal vertical rectus abdominis myocutaneous flap
    Brian S Glatt
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Plast Surg 56:526-30; discussion 530-1. 2006
    ..It has a low incidence of complications, low morbidity, and is easy to perform with a high success rate...
  39. ncbi The innervated anterolateral thigh flap: anatomical study and clinical implications
    Diego Ribuffo
    Division of Plastic Surgery, University of Rome La Sapienza, Rome, Italy
    Plast Reconstr Surg 115:464-70. 2005
    ..This can be helpful if one wants to harvest the flap under local anesthesia. Sensate bilobed flaps can be harvested when dual innervated flaps are required...
  40. ncbi A novel murine island skin flap for ischemic preconditioning
    Soner Tatlidede
    Plastic Surgery Research Laboratory, Division of Plastic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Surg Res 154:112-7. 2009
    ..Our first aim was to describe a novel murine skin flap model with a definable, reproducible injury. Our second aim was to test the usefulness of this model by demonstrating mitigation of injury via ischemic preconditioning...
  41. ncbi Clinical review of three types of platysma myocutaneous flap
    T Su
    Department of Oral and Maxillofacial Surgery, Xiangya Hospital, Central South University, Changsha 410008, PR China
    Int J Oral Maxillofac Surg 35:1011-5. 2006
    ..The survival rates of transverse and vertical platysma myocutaneous flaps preserving the facial artery and vein were higher than vertical flap that sacrificed the facial artery and vein...
  42. ncbi Improving outcomes in bilateral breast reconstruction using autogenous tissue
    Stephen J Vega
    Division of Plastic Surgery, University of Rochester Medical Center, Rochester, NY 14623, USA
    Ann Plast Surg 56:487-90; discussion 490-1. 2006
    ....
  43. ncbi Peroneal artery perforator-based propeller flap reconstruction of the lateral distal lower extremity after tumor extirpation: case report and literature review
    Ariel N Rad
    Division of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Microsurgery 28:663-70. 2008
    ....
  44. ncbi Pectoralis major myocutaneous flap for hypopharyngeal reconstruction
    Giuseppe Spriano
    Department of Otorhinolaryngology, Ospedale di Circolo, Varese, Italy
    Plast Reconstr Surg 110:1408-13; discussion 1414-6. 2002
    ..The other reconstructive options require surgical transgression of the abdomen and/or thorax in patients affected by malnutrition and other chronic systemic disorders...
  45. ncbi Effect of flapless surgery on pain experienced in implant placement using an image-guided system
    Thomas Fortin
    Department of Oral Surgery, Dental University of Lyon, France
    Int J Oral Maxillofac Implants 21:298-304. 2006
    ..The aim of this study was to compare the pain experienced after implant placement with 2 different surgical procedures: a flapless surgical procedure using an image-guided system based on a template and an open-flap procedure...
  46. ncbi Omental transposition: the final solution for major sternal wound infection
    Kalliopi Athanassiadi
    1st Department of Thoracic Surgery, General Hospital for Chest Diseases, Athens, Greece
    Asian Cardiovasc Thorac Ann 15:200-3. 2007
    ..Radical debridement along with omental flap transposition provides definitive control of the infection in cases of failure of other semi-conservative or surgical interventions. Prognosis depends on the general condition of the patient...
  47. ncbi Management of pilonidal sinus disease with oblique excision and bilateral gluteus maximus fascia advancing flap: result of 278 patients
    Osman Krand
    General Surgery Department, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey
    Dis Colon Rectum 52:1172-7. 2009
    ..We investigated the potential advantages of this advancing flap technique, which we developed...
  48. ncbi Skin-sparing mastectomy
    Giles H Cunnick
    Department of Breast Surgery, St George s Hospital, Tooting, London, United Kingdom
    Am J Surg 188:78-84. 2004
    ..It facilitates immediate breast reconstruction using an implant or myocutaneous flap, resulting in excellent cosmesis...
  49. ncbi Comparison of Karydakis flap reconstruction versus primary midline closure in sacrococcygeal pilonidal disease: results of 200 military service members
    Mehmet Fatih Can
    Department of Surgery, Ardahan Army Community Hospital, 75000, Ardahan, Turkey
    Surg Today 39:580-6. 2009
    ..The goal of this study was to compare the Karydakis flap reconstruction with a primary midline closure (PMC) in the treatment of patients with SPD...
  50. ncbi Improved safety of autologous breast reconstruction surgery by stabilisation of microsurgical vessel anastomoses using fibrin sealant in 349 free DIEP or fascia-muscle-sparing (fms)-TRAM flaps: a two-centre study
    Christoph Andree
    Department of Plastic and Aesthetic Surgery, Interdisciplinary Breast Centre, Sana Kliniken, Gerresheim Hospital, Dusseldorf, Germany
    Breast 17:492-8. 2008
    ..We routinely perform free DIEP flap and fascia-muscle-sparing (fms) TRAM flap procedures using fibrin sealant to stabilise anastomosed vessels, thus avoiding some of the difficulties associated with microsurgical anastomoses...
  51. ncbi Reconstruction after extirpation of sacral malignancies
    Jose Diaz
    University of Miami School of Medicine, DeWitt Daughtry Department of Surgery, FL, USA
    Ann Plast Surg 51:126-9. 2003
    ..The authors' experience suggests that this combination of techniques is a reliable approach for reconstruction of these extensive surgical defects...
  52. ncbi Morbidity after flap reconstruction of hypopharyngeal defects
    Jonathan R Clark
    Department of Otolaryngology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
    Laryngoscope 116:173-81. 2006
    ..In addition, we detail a reconstructive algorithm for management of partial and total laryngopharyngectomy defects...
  53. ncbi Flap prefabrication - the bridge between conventional flaps and tissue-engineered flaps
    B K Tan
    Department of Plastic Surgery, Singapore General Hospital, Singapore
    Ann Acad Med Singapore 33:662-6. 2004
    ..Future applications incorporating biomaterials and cultured cells will usher in the era of tissue-engineered flaps...
  54. ncbi Surgical management of bisphosphonate induced osteonecrosis of the jaws
    R A Williamson
    Department of Oral Surgery, Faculty of Medicine and Dentistry, University of Western Australia, 17 Monash Avenue, Perth, WA 6009, Australia
    Int J Oral Maxillofac Surg 39:251-5. 2010
    ..It should be recognized that while the results of this paper are encouraging, some cases will be resistant to all treatments...
  55. ncbi Immediate reconstruction using inframammary adipofascial flap of the anterior rectus sheath after partial mastectomy
    Yuko Kijima
    Department of Surgical Oncology, Breast and Endocrine Surgery, Kagoshima University Graduate School of Medical and Dental Sciences 8 35 1, Sakuragaoka, Kagoshima 890 8520, Japan
    Am J Surg 193:789-91. 2007
    ..A tongue shaped flap composed of the subcutaneous fat and the anterior sheath of rectus abdominis muscle is pulled up and a C-shaped flap is rotated, gathered, and inserted to reconstruct the breast defect...
  56. ncbi Day-case Karydakis flap for pilonidal sinus
    John H Anderson
    Department of Coloproctology, Glasgow Royal Infirmary, 16 Alexandra Parade, Glasgow, United Kingdom
    Dis Colon Rectum 51:134-8. 2008
    ..Previous studies had reported in-patient protocols. This cohort study was designed to assess the feasibility, safety, and practicalities of day-case Karydakis flap surgery. Factors relating to wound healing also were explored...
  57. ncbi Usefulness of breast-volume replacement using an inframammary adipofascial flap after breast-conservation therapy
    Tomoko Ogawa
    Department of Hepatobiliary Pancreatic Surgery and Breast Surgery, Mie University Graduate School of Medicine, Mie, Japan
    Am J Surg 193:514-8. 2007
    ..We believe this to be a useful surgical modality for the reconstruction of BCT in the inferior portion breast cancer...
  58. ncbi The gluteus maximus muscle flap for reconstruction of sacral chordoma defects
    Poh Koon Koh
    Department of Plastic Surgery, Singapore General Hospital, Singapore
    Ann Plast Surg 53:44-9. 2004
    ..A longitudinally split flap was used for secondary reconstruction of a partially obliterated defect (patient 4). Over a mean follow-up period of 8 months, there was no wound breakdown and all patients were ambulant...
  59. ncbi Randomized clinical trial of no wound drains and early discharge in the treatment of women with breast cancer
    A D Purushotham
    Department of Surgery, Western Infirmary, University of Edinburgh, Edinburgh, UK
    Br J Surg 89:286-92. 2002
    ..The aim of this study was to perform a prospective randomized clinical trial to evaluate a new surgical technique of suturing flaps without wound drainage, combined with early discharge, in women undergoing surgery for breast cancer...
  60. ncbi Reconstruction of the hypopharynx: current trends
    Jeremy D Richmon
    University of California, San Diego, Division of Otolaryngology Head and Neck Surgery San Diego, California 92103 889, USA
    Curr Opin Otolaryngol Head Neck Surg 15:208-12. 2007
    ..Trends continue to evolve as many viable options exist, depending on individual patient characteristics and institutional preferences. The article reviews the most current literature available on the subject...
  61. ncbi Femtosecond lenticule extraction for the correction of myopia: preliminary 6-month results
    Marcus Blum
    Department of Ophthalmology, Helios Hospital Erfurt, Nordhäusser Str 74, 99089, Erfurt, Germany
    Graefes Arch Clin Exp Ophthalmol 248:1019-27. 2010
    ..To report the 6-month results of a new method of refractive correction, femtosecond lenticule extraction (FLEx), and the preliminary outcomes in the first 108 eyes...
  62. ncbi Corneal architecture of femtosecond laser and microkeratome flaps imaged by anterior segment optical coherence tomography
    Burkhard von Jagow
    Department of Ophthalmology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Cataract Refract Surg 35:35-41. 2009
    ..To assess and compare the morphology of laser in situ keratomileusis flaps (LASIK) created by a 60 kHz femtosecond laser and a mechanical microkeratome...
  63. ncbi Rhomboid excision and Limberg flap for managing pilonidal sinus: long-term results in 411 patients
    M Akin
    Department of General Surgery, Gazi University School of Medicine, Ankara, Turkey
    Colorectal Dis 10:945-8. 2008
    ..To investigate the results of rhomboid excision and the Limberg flap procedure to treat pilonidal sinus disease...
  64. ncbi Multicenter prospective randomized trial comparing modified Limberg flap transposition and Karydakis flap reconstruction in patients with sacrococcygeal pilonidal disease
    Mehmet Fatih Can
    Department of Surgery, Ardahan Army Community Hospital, Ardahan, Turkey
    Am J Surg 200:318-27. 2010
    ..There is still no consensus as to the optimal treatment for sacrococcygeal pilonidal disease (SPD). Many recommend off-midline closure, if any excisional procedure is to be selected...
  65. ncbi Outcome comparison between free and pedicled TRAM flap breast reconstruction in the obese patient
    S L Moran
    Division of Plastic Surgery, University of Rochester Medical Center, NY 14642, USA
    Plast Reconstr Surg 108:1954-60; discussion 1961-2. 2001
    ..Surgeons should use the technique with which they are most familiar to obtain consistent results...
  66. ncbi Is routine cavity drainage necessary in Karydakis flap operation? A prospective, randomized trial
    Ahmet Gurer
    Department of General Surgery, Ataturk Egitim ve Arastirma Hospital, Ankara, Turkey
    Dis Colon Rectum 48:1797-9. 2005
    ..Different surgical techniques for pilonidal disease have been described in the literature. In this study our aim was to evaluate the influence of routine cavity drainage in the Karydakis flap technique...
  67. ncbi Awful considerations with LCP instrumentation: a new pitfall
    Hamid Namazi
    Department of Orthopaedic Surgery, Shiraz University of Medical Sciences, Chamran Hospital, 71345 Shiraz, Iran
    Arch Orthop Trauma Surg 127:573-5. 2007
    ..But, there is no study about the potential soft tissue pitfalls that may occur. There is an attempt in this study to achieve this objective...
  68. ncbi Randomized clinical trial of local gentamicin-collagen treatment in advancement flap repair for anal fistula
    U M Gustafsson
    Department of Surgery, University Hospital, S 751 85 Uppsala, Sweden
    Br J Surg 93:1202-7. 2006
    ..A possible cause of non-healing is local infection of the flap. The aim of this study was to evaluate whether local antibiotic treatment with gentamicin-collagen improves healing after endoanal advancement flap repair for anal fistula...
  69. ncbi Smoking impairs rectal mucosal bloodflow--a pilot study: possible implications for transanal advancement flap repair
    David D E Zimmerman
    Colorectal Research Group of Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
    Dis Colon Rectum 48:1228-32. 2005
    ..018; Mann-Whitney). In conclusion, it seems likely that impaired wound healing caused by a diminished rectal mucosal perfusion is a contributing factor in the breakdown of advancement flaps in patients who smoke cigarettes...
  70. ncbi Corneal flap complications in refractive surgery: Part 1: development of an experimental animal model
    Mike P Holzer
    Magill Research Center for Vision Correction, Storm Eye Institute, Medical University of South Carolina, Charleston 29425, USA
    J Cataract Refract Surg 29:795-802. 2003
    ..To report the outcome, learning curve, and complication rates of an experimental animal model for corneal flaps in refractive surgery...
  71. ncbi Free-flap mandibular reconstruction: a 10-year follow-up study
    David A Hidalgo
    Division of Plastic Surgery, Cornell University Medical College, New York, NY, USA
    Plast Reconstr Surg 110:438-49; discussion 450-1. 2002
    ..Acceptable speech and appearance are restored and continue to be a source of patient satisfaction at least a decade after surgery...
  72. ncbi Aggressive primary treatment for poststernotomy acute mediastinitis: our experience with omental- and muscle flaps surgery
    P Schroeyers
    Department of Thoracic and Cardiovascular Surgery, Onze-Lieve-Vrouw Ziekenhuis, Moorselbaan 164, 9300 Aalst, Belgium
    Eur J Cardiothorac Surg 20:743-6. 2001
    ..CONCLUSION: In our experience, omental and pectoralis flaps for poststernotomy acute mediastinitis provides good outcome of our stable patients. We would be reluctant to use it as standard therapy in our unstable patients...
  73. ncbi Postoperative medical complications--not microsurgical complications--negatively influence the morbidity, mortality, and true costs after microsurgical reconstruction for head and neck cancer
    Neil F Jones
    Division of Plastic and Reconstructive Surgery, University of California Los Angeles School of Medicine, Los Angeles, CA, USA
    Plast Reconstr Surg 119:2053-60. 2007
    ..There remains, however, ongoing debate on whether the costs associated with this reconstructive approach merit its selection, especially considering poor patient prognoses and the high cost of care...
  74. ncbi Morbidity and cost differences between free flap reconstruction and pedicled flap reconstruction in oral and oropharyngeal cancer: Matched control study
    Ludwig E Smeele
    Department of Otolaryngology Head and Neck Surgery, Wharton Head and Neck Centre, The Toronto Hospital Princess Margaret Hospital, University of Toronto, Toronto, Ontario
    J Otolaryngol 35:102-7. 2006
    ....
  75. ncbi A longitudinal study of LASIK flap and stromal thickness with high-speed optical coherence tomography
    Yan Li
    Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA
    Ophthalmology 114:1124-32. 2007
    ..To assess corneal anatomic changes after LASIK with a high-speed corneal and anterior segment optical coherence tomography (CAS-OCT) system...
  76. ncbi Accuracy and precision of LASIK flap thickness using the IntraLase femtosecond laser in 1000 consecutive cases
    Gerard Sutton
    Auckland University, Save Sight and Eye Institute, Department of Ophthalmology, Sydney Eye Hospital, Sydney, Australia
    J Refract Surg 24:802-6. 2008
    ..To report the safety and flap thickness predictability of LASIK using the IntraLase femtosecond laser...
  77. ncbi Comparing conventional gauze therapy to vacuum-assisted closure wound therapy: a prospective randomised trial
    C M Mouës
    Department of Plastic and Reconstructive Surgery, Erasmus University Medical Centre, Rotterdam, The Netherlands
    J Plast Reconstr Aesthet Surg 60:672-81. 2007
    ..We performed a prospective randomised clinical trial to compare the efficacy of vacuum therapy to conventional moist gauze therapy in this stage of wound treatment...
  78. ncbi Laser in situ keratomileusis flap complications using mechanical microkeratome versus femtosecond laser: retrospective comparison
    Majid Moshirfar
    Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah, USA
    J Cataract Refract Surg 36:1925-33. 2010
    ..To compare the incidence of flap complications after creation of laser in situ keratomileusis (LASIK) flaps using a zero-compression microkeratome or a femtosecond laser...
  79. ncbi Comparison of flap adhesion strength using the Amadeus microkeratome and the IntraLase iFS femtosecond laser in rabbits
    Michael C Knorz
    FreeVis LASIK Zentrum, Mannheim, Germany
    J Refract Surg 24:875-8. 2008
    ..To compare adhesion strength of flaps created with a mechanical microkeratome and the IntraLase femtosecond laser as well as to analyze the effect of different side-cut configurations...
  80. ncbi The pectoralis major myocutaneous flap revisited: a reliable technique for head and neck reconstruction
    J Nicholas McLean
    Emory Division of Plastic and Reconstructive Surgery, Atlanta, GA 30308, USA
    Ann Plast Surg 64:570-3. 2010
    ..Patients who had radiation therapy had significantly higher complication rates. The PMMF flap remains a very versatile technique with proven reliability for soft tissue coverage of many head and neck defects...
  81. ncbi Practical guidelines for repair of partial mastectomy defects using the breast reduction technique in patients undergoing breast conservation therapy
    Steven J Kronowitz
    Department of Plastic and Reconstructive Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Plast Reconstr Surg 120:1755-68. 2007
    ..The authors previously compared the local tissue rearrangement, breast reduction, and latissimus dorsi flap reconstruction techniques for repairing partial mastectomy defects and showed the benefits of breast reduction...
  82. ncbi Effect of obesity on flap and donor-site complications in free transverse rectus abdominis myocutaneous flap breast reconstruction
    D W Chang
    Department of Plastic and Reconstructive Surgery at the University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Plast Reconstr Surg 105:1640-8. 2000
    ..Patients who are morbidly obese are at very high risk of failure and complications and should avoid any type of TRAM flap breast reconstruction...
  83. ncbi Use of the buccal fat pad in the reconstruction and prosthetic rehabilitation of oncological maxillary defects
    M A Amin
    S W London Regional Maxillofacial Service, St George s Hospital Medical School, Blackshaw Road, Tooting, London SW170QT, UK
    Br J Oral Maxillofac Surg 43:148-54. 2005
    ..Eight patients so far have been rehabilitated with small dentures. In conclusion, the buccal fat pad flap is a simple, quick, and reliable method of reconstruction of small to medium-sized posterior maxillary alveolar defects...
  84. ncbi Complications of vascularized fibula graft for reconstruction of long bones
    Kouichi Arai
    Department of Orthopedic Surgery, Hirosaki University School of Medicine, Zaifu cho 5, Hirosaki, Aomori 036 8562, Japan
    Plast Reconstr Surg 109:2301-6. 2002
    ..Vascularized fibular grafting offers the patient a great deal of benefit; however, this graft has a concomitant high risk of complications. Great attention to detail must be paid to prevent postoperative complications...
  85. ncbi Smoking affects the outcome of transanal mucosal advancement flap repair of trans-sphincteric fistulas
    D D E Zimmerman
    Department of Surgery, Erasmus Medical Centre, Rotterdam, The Netherlands
    Br J Surg 90:351-4. 2003
    ..The aim of the study was to identify variables affecting the outcome of transanal advancement flap repair (TAFR) for perianal fistulas of cryptoglandular origin...
  86. ncbi Skin-sparing mastectomy and immediate autologous breast reconstruction in locally advanced breast cancer patients: a UBC perspective
    Adelyn L Ho
    Department of Surgery, Division of Plastic and Reconstructive Surgery, University of British Columbia, Vancouver, British Columbia, Canada
    Ann Surg Oncol 19:892-900. 2012
    ....
  87. ncbi Reconstruction of circumferential oro- and hypopharyngeal defects with U-shaped pectoralis major myocutaneous flap
    Sven Saussez
    Department of Otorhinolaryngology Head and Neck Surgery, CHU Saint Pierre, Bruxelles, Belgium
    Otolaryngol Head Neck Surg 134:823-9. 2006
    ..The purpose of the study was to evaluate the effectiveness of a U-shaped pectoralis major myocutaneous flap (PMMF) to reconstruct a large circumferential defect involving the oro- and hypopharynx...
  88. ncbi Histologic, ultrastructural, and immunofluorescent evaluation of human laser-assisted in situ keratomileusis corneal wounds
    Daniel G Dawson
    Emory Eye Center, Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA
    Arch Ophthalmol 123:741-56. 2005
    ..To evaluate human corneas after laser-assisted in situ keratomileusis at different postoperative intervals...
  89. ncbi Two designs of platysma myocutaneous flap for reconstruction of oral and facial defects following cancer surgery
    L W Peng
    Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan 430079, PR China
    Int J Oral Maxillofac Surg 34:507-13. 2005
    ..It is recommended that the vertical design be used for reconstruction of buccal mucosa defects, and the transverse design for mouth-floor and facial defects...
  90. ncbi Surgical management of traumatic LASIK flap dislocation with macrostriae and epithelial ingrowth 14 years postoperatively
    Derick G Holt
    Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah, USA
    J Cataract Refract Surg 38:357-61. 2012
    ..This case represents the longest documented interval from LASIK surgery to traumatic flap dislocation. We describe our surgical approach to the management of this type of injury and present a video illustrating the technique...
  91. ncbi Anteriorly based inferior turbinate flap for endoscopic skull base reconstruction
    Ziv Gil
    The Head and Neck Surgery Unit, Department of Otolaryngology Head and Neck Surgery, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Israel Tel Aviv, Israel
    Otolaryngol Head Neck Surg 146:842-7. 2012
    ..In this article, the authors describe the anteriorly pedicled inferior turbinate flap (AITF) as a method for endoscopic reconstruction of anterior skull base defects...
  92. ncbi Use of custom-made stockings to control postoperative leg and foot edema following free tissue transfer and external fixation of fractures
    Cigdem Unal
    Department of Plastic, Reconstructive and Aesthetic Surgery, Kocaeli University Medical Faculty, Umuttepe, Kocaeli, Turkey
    J Foot Ankle Surg 51:246-8. 2012
    ..They are easy to apply, affordable, and can be tailored from regular compression stockings according to the needs of the patients...
  93. ncbi Free radial forearm flap versus pectoralis major myocutaneous flap reconstruction of oral and oropharyngeal defects: a cost analysis
    R de Bree
    Department of Otolaryngology, Head and Neck Surgery, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    Clin Otolaryngol 32:275-82. 2007
    ..Cost implications of radial forearm flap reconstruction within the context of the overall health care in a particular system need to be investigated particularly before it is labelled as 'costly only'...
  94. ncbi Hemiface allotransplantation in the mouse
    Robert Sucher
    Research Laboratory Innsbruck Medical University Anichstrasse 35 A 6020 Innsbruck, Austria
    Plast Reconstr Surg 129:867-70. 2012
    ..The microsurgically demanding procedure may be used to investigate basic immunology and rejection and to address questions related to nerve regeneration in reconstructive face transplantation...
  95. ncbi Reconstruction of hypopharyngeal defects with submental flap after laryngopharyngectomy
    Jih Chin Lee
    Department of Otolaryngology Head and Neck Surgery, Tri Service General Hospital, National Defense Medical Center, 325, Cheng Kung Road, Sec 2, Neihu District, Taipei, 114, Taiwan
    Eur Arch Otorhinolaryngol 270:319-23. 2013
    ..Our initial reports confirm that this kind of reconstruction is feasible and time-saving, and restored a good quality of life...
  96. ncbi Combination of rat vest, teeth shortening, and nail cutting to prevent autocannibalization and protect surgical flaps
    Omer Ozkan
    Plast Reconstr Surg 117:1671. 2006
  97. ncbi Repair of exposed hydroxyapatite orbital implants by subconjunctival tissue flaps
    Linna Lu
    Department of Ophthalmology, Ninth People s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People s Republic of China
    J Craniofac Surg 22:1452-6. 2011
    ..The purpose of the study was to determine the feasibility of the use of subconjunctival tissue flaps to repair exposed hydroxyapatite (HA) orbital implants...
  98. ncbi Vascularized bone grafts for upper limb reconstruction: defects at the distal radius, wrist, and hand
    Konstantinos N Malizos
    Department of Orthopaedic Surgery, Faculty of Medicine, School of Health Sciences, University of Thessalia, Larissa, Greece
    J Hand Surg Am 35:1710-8. 2010
    ..This article focuses on defects of the distal radius, the wrist, and the hand...
  99. ncbi [Vascularized iliac crest and distal radius reconstruction]
    L Pic Gomis
    Service de Chirurgie Plastique, CHU Lapeyronie, 371 Avenue Doyen Gaston Giraud, Montpellier, France
    Chir Main 29:S49-58. 2010
    ..Composite cutaneous bone flaps are also detailed. In the third chapter, they detail informations about treatment of distal radius bone defects with associated skeen flap if necessary...
  100. pmc Microcystic adnexal carcinoma of the centrofacial region: a case report
    G A Beltramini
    Department of Maxillo Facial Surgery, University of Milan, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy
    Acta Otorhinolaryngol Ital 30:213. 2010
    ....
  101. ncbi N-acetylcysteine attenuates leukocytic inflammation and microvascular perfusion failure in critically ischemic random pattern flaps
    A C Bächle
    Institute for Clinical and Experimental Surgery, University of Saarland, 66421 Homburg Saar, Germany
    Microvasc Res 82:28-34. 2011
    ..Microcirculatory dysfunction causes ischemia resulting in tissue necrosis. N-acetylcysteine (NAC) has been shown capable of protecting tissue from ischemic necrosis. However, the mechanism of action of NAC is yet not fully understood...

Research Grants14

  1. Assessment of Reconstructive Surgical Flaps Using Spatially Resolved Tissue Oxima
    Anthony J Durkin; Fiscal Year: 2012
    ..In parallel with the Phase II research outlined herein, we will aggressively pursue commercialization of a medical device based on MI. ..
  2. Sustained Regeneration of Soft Tissue Defects
    Jonathan Kluge; Fiscal Year: 2012
    ..All current clinical approaches, including surgical flaps, artificial fillers, and free fat transplant ll present significant limitations...
  3. Molecular Heparan Sulfate Delivery in Guided Tissue Regeneration
    Arthur DeCarlo; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  4. EFFECTS OF TREATMENT ON EARLY ONSET PERIODONTITIS
    Frank Roberts; Fiscal Year: 2003
    ..This project will enhance our understanding of the effects of root debridement on host defense systems and help to develop more effective treatment options for this complex inflammatory disease. ..
  5. Microarray Analysis of Wounds
    AMY COLWELL; Fiscal Year: 2004
    ..We hypothesize these genes can be used to modulate the biology of adult wound healing. This first step will form our basis for developing treatment to induce scarless healing. ..
  6. Bone Marrow Stromal Cells for Bladder Tissue Engineering
    Yuanyuan Zhang; Fiscal Year: 2006
    ..3.3) Evaluate extent of bladder regeneration at different time points through histology, contractility assays, and immunohistochemical staining. [unreadable] [unreadable] [unreadable]..
  7. COLLABORATIVE INITIAL GLAUCOMA TREATMENT STUDY
    Henry Jampel; Fiscal Year: 2002
    ....
  8. EARLY DETECTION OF GLAUCOMA DAMAGE
    Henry Jampel; Fiscal Year: 2004
    ..This assessment of the RTA and NFA will help to establish their utility as outcome measures for clinical management of glaucoma, epidemiological research, and clinical trials. ..
  9. GLAUCOMA SURGICAL OUTCOMES STUDY
    Henry Jampel; Fiscal Year: 2001
    ..The results of the study may allow physicians to reduce the morbidity of glaucoma surgery by altering their indications for surgery, surgical technique, and postoperative follow-up. ..
  10. IN VIVO MECHANISMS OF LOCAL STATIN-INDUCED BONE
    Richard Reinhardt; Fiscal Year: 2004
    ..abstract_text> ..
  11. DONOR SPECIFIC IMMUNOSUPPRESSION TO TRACHEAL ALLOGRAFTS
    Eric Genden; Fiscal Year: 2004
    ..Specific Aim II will focus on alternative methods of inducing donor specific tolerance to tracheal allografts. Specific Aim III will focus on the behavior of the tracheal allograft and its affect upon the established state of tolerance. ..
  12. Neurogenesis in the Human Brain
    Alfredo Quinones Hinojosa; Fiscal Year: 2003
    ....
  13. CO POISONING IN THE CONTEXT OF A REPERFUSION INJURY
    Stephen Thom; Fiscal Year: 2003
    ..The research plan is aimed to test the hypothesis that immune responses and the associated oxidative stress cause neurological injuries. ..
  14. Quantitating Absorption of Complex Chemical Mixtures
    Jim Riviere; Fiscal Year: 2009
    ..abstract_text> ..