surgical mesh

Summary

Summary: Any woven or knit material of open texture used in surgery for the repair, reconstruction, or substitution of tissue. The mesh is usually a synthetic fabric made of various polymers. It is occasionally made of metal.

Top Publications

  1. ncbi Surgical intervention for complications of tension-free vaginal tape procedure
    Bjoern G Volkmer
    Department of Urology, University of Ulm, Ulm, Germany
    J Urol 169:570-4. 2003
  2. ncbi Ventral hernia repair: a study of current practice
    C A Courtney
    University Department of Surgery, Western Infirmary, G11 6NT, Glasgow, UK
    Hernia 7:44-6. 2003
  3. ncbi Long-term outcome of 254 complex incisional hernia repairs using the modified Rives-Stoppa technique
    Corey W Iqbal
    Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    World J Surg 31:2398-404. 2007
  4. ncbi Hernias: inguinal and incisional
    Andrew Kingsnorth
    Derriford Hospital, Level 7, Plymouth, UK
    Lancet 362:1561-71. 2003
  5. pmc Long-term follow-up of a randomized controlled trial of suture versus mesh repair of incisional hernia
    Jacobus W A Burger
    Department of General Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands
    Ann Surg 240:578-83; discussion 583-5. 2004
  6. ncbi Incisional ventral hernias: review of the literature and recommendations regarding the grading and technique of repair
    Karl Breuing
    Brigham and Women s Faulkner Hospital, Harvard Medical School, Boston, MA, USA
    Surgery 148:544-58. 2010
  7. ncbi Meta-analysis of randomized controlled trials comparing open and laparoscopic ventral and incisional hernia repair with mesh
    S S Forbes
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Br J Surg 96:851-8. 2009
  8. ncbi Vacuum-assisted wound closure and mesh-mediated fascial traction--a novel technique for late closure of the open abdomen
    Ulf Petersson
    Department of Surgery, University Hospital Malmo, 205 02 Malmo, Sweden
    World J Surg 31:2133-7. 2007
  9. pmc Laparoscopic repair of ventral hernias: nine years' experience with 850 consecutive hernias
    B Todd Heniford
    Department of Surgery, Carolinas Medical Center, Charlotte, North Carolina 28232, USA
    Ann Surg 238:391-9; discussion 399-400. 2003
  10. ncbi Prevention of parastomal hernia by placement of a polypropylene mesh at the primary operation
    Ismail Gogenur
    Department of Surgical Gastroenterology, University of Copenhagen, Gentofte Hospital, Hellerup, Denmark
    Dis Colon Rectum 49:1131-5. 2006

Detail Information

Publications299 found, 100 shown here

  1. ncbi Surgical intervention for complications of tension-free vaginal tape procedure
    Bjoern G Volkmer
    Department of Urology, University of Ulm, Ulm, Germany
    J Urol 169:570-4. 2003
    ..Cases of complications requiring surgical revision are reported to be rare. We report on 6 patients with complications necessitating surgery...
  2. ncbi Ventral hernia repair: a study of current practice
    C A Courtney
    University Department of Surgery, Western Infirmary, G11 6NT, Glasgow, UK
    Hernia 7:44-6. 2003
    ..Surgical practice varies widely in the repair of ventral wall hernias. Clinical trials are required to establish the best method of repair for this common condition...
  3. ncbi Long-term outcome of 254 complex incisional hernia repairs using the modified Rives-Stoppa technique
    Corey W Iqbal
    Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    World J Surg 31:2398-404. 2007
    ..Repair of complex incisional hernias poses a major challenge...
  4. ncbi Hernias: inguinal and incisional
    Andrew Kingsnorth
    Derriford Hospital, Level 7, Plymouth, UK
    Lancet 362:1561-71. 2003
    ..Many of the principles of management apply equally to inguinal and incisional hernias. We recommend that the more difficult and complex of the procedures be referred to specialists...
  5. pmc Long-term follow-up of a randomized controlled trial of suture versus mesh repair of incisional hernia
    Jacobus W A Burger
    Department of General Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands
    Ann Surg 240:578-83; discussion 583-5. 2004
    ..The objective of this study was to determine the best treatment of incisional hernia, taking into account recurrence, complications, discomfort, cosmetic result, and patient satisfaction...
  6. ncbi Incisional ventral hernias: review of the literature and recommendations regarding the grading and technique of repair
    Karl Breuing
    Brigham and Women s Faulkner Hospital, Harvard Medical School, Boston, MA, USA
    Surgery 148:544-58. 2010
    ..A generalized approach and technical considerations for the repair of incisional ventral hernias are outlined, including the appropriate use of component separation and the growing role of biologic repair materials...
  7. ncbi Meta-analysis of randomized controlled trials comparing open and laparoscopic ventral and incisional hernia repair with mesh
    S S Forbes
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Br J Surg 96:851-8. 2009
    ..Laparoscopic ventral and incisional hernia repair has been reported in a number of small trials to have equivalent or superior outcomes to open repair...
  8. ncbi Vacuum-assisted wound closure and mesh-mediated fascial traction--a novel technique for late closure of the open abdomen
    Ulf Petersson
    Department of Surgery, University Hospital Malmo, 205 02 Malmo, Sweden
    World J Surg 31:2133-7. 2007
    ..Feasibility and short-term outcome of a novel combination of techniques for managing the open abdomen are presented...
  9. pmc Laparoscopic repair of ventral hernias: nine years' experience with 850 consecutive hernias
    B Todd Heniford
    Department of Surgery, Carolinas Medical Center, Charlotte, North Carolina 28232, USA
    Ann Surg 238:391-9; discussion 399-400. 2003
    ..To evaluate the efficacy and safety of laparoscopic repair of ventral hernias...
  10. ncbi Prevention of parastomal hernia by placement of a polypropylene mesh at the primary operation
    Ismail Gogenur
    Department of Surgical Gastroenterology, University of Copenhagen, Gentofte Hospital, Hellerup, Denmark
    Dis Colon Rectum 49:1131-5. 2006
    ..We studied the safety and prophylactic effect of placing a newly designed polypropylene mesh in an onlay position at the primary operation...
  11. ncbi Comparison of contracture, adhesion, tissue ingrowth, and histologic response characteristics of permanent and absorbable barrier meshes in a porcine model of laparoscopic ventral hernia repair
    C R Deeken
    Department of Surgery, Section of Minimally Invasive Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8109, St Louis, MO 63110, USA
    Hernia 16:69-76. 2012
    ..histologic characteristics of a novel absorbable barrier mesh (Ventrio™ ST Hernia Patch) compared to existing permanent (Ventrio™ Hernia Patch) and absorbable barrier meshes (Sepramesh™ IP Composite and PROCEED™ Surgical Mesh).
  12. ncbi Tissue ingrowth and bowel adhesion formation in an animal comparative study: polypropylene versus Proceed versus Parietex Composite
    B P Jacob
    Department of Surgery, Mount Sinai School of Medicine, 1010 Fifth Avenue, New York, NY, USA
    Surg Endosc 21:629-33. 2007
    ..Currently, few data are available from randomized trials comparing the commercially available prostheses...
  13. ncbi Parastomal hernia
    P W G Carne
    Colorectal Unit, Department of Surgery, Christchurch Hospital, Riccarton Avenue, Christchurch, New Zealand
    Br J Surg 90:784-93. 2003
    ..This article reviews the incidence of hernia, the technical factors related to the construction of the stoma that may influence the incidence, and the success of the different methods of repair...
  14. ncbi Laparoscopic repair of parastomal hernias: early results
    B Safadi
    Department of Surgery, Stanford University, Veteran Affairs Palo Alto Health Care System, 3801 Miranda Avenue, 112G, Palo Alto, CA 94304, USA
    Surg Endosc 18:676-80. 2004
    ..The purpose of this study was to review our institution's experience with the laparoscopic repair of parastomal hernias...
  15. pmc Three-year results from a preclinical implantation study of a long-term resorbable surgical mesh with time-dependent mechanical characteristics
    H Hjort
    Novus Scientific, Rapsgatan 25, Uppsala, Sweden
    Hernia 16:191-7. 2012
    ..the biocompatibility, local tissue effects and performance of a synthetic long-term resorbable test mesh (TIGR(®) Matrix Surgical Mesh) compared to a non-resorbable polypropylene control mesh following implantation in a sheep model.
  16. ncbi Long term review of laparoscopic sacrocolpopexy
    P J Higgs
    Urogynaecology Department, Royal Women s Hospital, Melbourne, Australia
    BJOG 112:1134-8. 2005
    ..Assessment of long term outcome following laparoscopic sacrocolpopexy...
  17. ncbi Physicomechanical evaluation of polypropylene, polyester, and polytetrafluoroethylene meshes for inguinal hernia repair
    Corey R Deeken
    Department of Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Am Coll Surg 212:68-79. 2011
    ..The objectives of this study were to propose standard techniques, perform physicomechanical testing, and classify materials commonly used for inguinal hernia repair...
  18. ncbi Current approaches to inguinal hernia repair
    Samir S Awad
    Michael E DeBakey Houston Veterans Affairs Medical Center, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Operative Care Line, 2002 Holcombe Boulevard, VA 112, Houston, Texas 77030, USA
    Am J Surg 188:9S-16S. 2004
    ..Although each of these repairs boasts its successes, there are advantages and disadvantages to each approach. This article highlights each of these repairs through review of the literature...
  19. ncbi Parastomal hernias
    Leif A Israelsson
    Department of Surgery and Perioperative Science, Umea University, Umea, Sweden
    Surg Clin North Am 88:113-25, ix. 2008
    ..Several mesh repair techniques are used in open and laparoscopic surgery, but randomized trials comparing various techniques and with long-term follow-up are needed for better evidence...
  20. ncbi Safety and outcome of use of nonabsorbable mesh for repair of fascial defects in the presence of open bowel
    Daniel J Geisler
    Section of Colorectal Surgery, Saint Vincent Health Center, Erie, Pennsylvania, USA
    Dis Colon Rectum 46:1118-23. 2003
    ..The purpose of this study was to evaluate the safety and efficacy of nonabsorbable mesh used for hernia repair in the presence of a stoma or at the time of colon resection...
  21. ncbi Assessment of adhesion formation to intra-abdominal polypropylene mesh and polytetrafluoroethylene mesh
    Brent D Matthews
    Department of General Surgery, and The James B Cannon Research Center, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
    J Surg Res 114:126-32. 2003
    ....
  22. ncbi Complications requiring reoperation following vaginal mesh kit procedures for prolapse
    Rebecca U Margulies
    Pelvic Floor Research Group and the Department of Obstetrics and Gynecology, University of Michigan School of Medicine, Ann Arbor, MI, USA
    Am J Obstet Gynecol 199:678.e1-4. 2008
    ..The objective of the study was to the characterize the symptoms and management of vaginal mesh-related complications requiring operative intervention...
  23. ncbi Degradation of mesh coatings and intraperitoneal adhesion formation in an experimental model
    M H F Schreinemacher
    Department of General Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands
    Br J Surg 96:305-13. 2009
    ..In this experimental study the ability of different coated and uncoated meshes to attenuate adhesion formation was examined...
  24. ncbi Titanium coating of a polypropylene mesh for hernia repair: effect on biocompatibilty
    K Junge
    Department of Surgery, Technical University of Aachen, Pauwelsstrasse 30, 52057, Aachen, Germany
    Hernia 9:115-9. 2005
    ..No significant improvement of biocompatibility was found when analyzing the effect of titanium coating compared to the pure polypropylene mesh structure...
  25. ncbi Late fascial closure in lieu of ventral hernia: the next step in open abdomen management
    Preston R Miller
    Department of Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27514, USA
    J Trauma 53:843-9. 2002
    ..We review a method of late primary fascial closure, thus eliminating the need for delayed reconstruction in some patients...
  26. ncbi Laparoscopic versus open ventral hernia mesh repair: a prospective study
    D Lomanto
    Minimally Invasive Surgical Centre, Department of Surgery, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
    Surg Endosc 20:1030-5. 2006
    ..This prospective study was performed to objectively analyze and compare the outcomes after open and laparoscopic ventral hernia repair...
  27. ncbi Randomized, controlled, prospective trial of the use of a mesh to prevent parastomal hernia
    Xavier Serra-Aracil
    Servei de Cirurgia General i Aparell Digestiu, Corporacio Sanitaria Parc Tauli, Parc Tauli s n, 08208 Sabadell, Barcelona, Spain
    Ann Surg 249:583-7. 2009
    ..The effect of the PH may range from discomfort to life-threatening complications. Surgical procedures for repairing PH are difficult to perform and present a high-failure rate...
  28. ncbi Prospective randomized trial of polyglactin 910 mesh to prevent recurrence of cystoceles and rectoceles
    P K Sand
    Evanston Continence Center, Division of Urogynecology, Evanston Northwestern Healthcare, Northwestern University Medical School, Illinois 60201, USA
    Am J Obstet Gynecol 184:1357-62; discussion 1362-4. 2001
    ..Thirteen recurrent rectoceles were noted 1 year postoperatively, with no differences between groups. CONCLUSION: Polyglactin 910 mesh was found to be useful in the prevention of recurrent cystoceles...
  29. ncbi Anterior colporrhaphy: a randomized trial of three surgical techniques
    A M Weber
    Department of Gynecology and Obstetrics, Cleveland Clinic Foundation, Ohio, USA
    Am J Obstet Gynecol 185:1299-304; discussion 1304-6. 2001
    ..The addition of polyglactin 910 mesh did not improve the cure rate compared with standard anterior colporrhaphy...
  30. ncbi Transvaginal repair of anterior and posterior compartment prolapse with Atrium polypropylene mesh
    Peter L Dwyer
    Urogynaecology Department, Mercy Hospital for Women, Melbourne, Australia
    BJOG 111:831-6. 2004
    ..To determine the efficacy and safety of a new technique using Atrium polypropylene mesh (Atrium, Hudson, New Hampshire, USA) as an overlay graft for repair of large or recurrent anterior and posterior compartment prolapse...
  31. ncbi Watchful waiting vs repair of inguinal hernia in minimally symptomatic men: a randomized clinical trial
    Robert J Fitzgibbons
    Department of Surgery, Creighton University, Omaha, Neb, USA
    JAMA 295:285-92. 2006
    ..Many men with inguinal hernia have minimal symptoms. Whether deferring surgical repair is a safe and acceptable option has not been assessed...
  32. pmc Classification of primary and incisional abdominal wall hernias
    F E Muysoms
    Department of Surgery, AZ Maria Middelares, Kortrijksesteenweg 1026, Ghent 9000, Belgium
    Hernia 13:407-14. 2009
    ..It is important to know whether the populations described in different studies are comparable...
  33. ncbi Prognosis factors in incisional hernia surgery: 25 years of experience
    C Langer
    Department of General Surgery, Georg August University Gottingen, Robert Koch Str 40, 37075 Gottingen, Germany
    Hernia 9:16-21. 2005
    ..The relevance of different factors, like operative technique, mesh material, and patient-related parameters concerning the outcome following mesh repair, are still under debate...
  34. ncbi Evaluation of new prosthetic meshes for ventral hernia repair
    J W A Burger
    Department of General Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands
    Surg Endosc 20:1320-5. 2006
    ..Recently, new meshes have been introduced. In an experimental rat study, their value was established and compared with that of meshes already available on the market...
  35. ncbi Randomized clinical trial of the use of a prosthetic mesh to prevent parastomal hernia
    A Janes
    Department of Surgery, Sundsvalls sjukhus, Sundsvall, Sweden
    Br J Surg 91:280-2. 2004
    ..The aim of this study was to determine the effect on stoma complications of using a mesh at the primary operation...
  36. ncbi Anterior colporrhaphy versus transvaginal mesh for pelvic-organ prolapse
    Daniel Altman
    Division of Obstetrics and Gynecology, Department of Clinical Science, Danderyd Hospital, Stockholm, Sweden
    N Engl J Med 364:1826-36. 2011
    ..The use of standardized mesh kits for repair of pelvic-organ prolapse has spread rapidly in recent years, but it is unclear whether this approach results in better outcomes than traditional colporrhaphy...
  37. ncbi Surgical management of inguinal hernia
    Brian Reuben
    Department of Surgery, Division of General Surgery, Salt Lake City VA Healthcare System and University of Utah School of Medicine, 30 North 1900 East, Room 3B110, SOM, Salt Lake City, UT 84132, USA
    Adv Surg 40:299-317. 2006
    ..Surgeons need to look at their own numbers and experience to decide which approach is better given the clinical situation based on their proficiency with the various techniques...
  38. ncbi Randomized clinical trial of mesh versus sutured wound closure after open abdominal aortic aneurysm surgery
    P M Bevis
    Department of Vascular Surgery, Cheltenham General Hospital, Cheltenham, UK
    Br J Surg 97:1497-502. 2010
    ..Incisional herniation is a common complication of abdominal aortic aneurysm (AAA) repair. This study investigated whether prophylactic mesh placement could reduce the rate of postoperative incisional hernia after open repair of AAA...
  39. ncbi Intraperitoneal treatment of incisional and umbilical hernias using an innovative composite mesh: four-year results of a prospective multicenter clinical trial
    J G Balique
    Clinique du Parc, 9 rue de la Piot, 42270 Saint Priest en Jarez, France
    Hernia 9:68-74. 2005
    ..In particular there was no early or long-term main complication due to the intraperitoneal location of the mesh...
  40. ncbi Management of complicated umbilical hernias in cirrhotic patients using permanent mesh: randomized clinical trial
    S A Ammar
    Department of Surgery, Assiut University Hospital, Assiut, Egypt
    Hernia 14:35-8. 2010
    ..The optimal management of complicated umbilical hernia in patients with liver cirrhosis is still undefined. The purpose of this study is to evaluate the use of polypropylene mesh to treat complicated umbilical hernia in cirrhotic patients...
  41. ncbi Surgical management of pelvic organ prolapse in women: the updated summary version Cochrane review
    Christopher M Maher
    Royal Brisbane and Wesley Hospitals Brisbane, Brisbane, Australia
    Int Urogynecol J 22:1445-57. 2011
    ..The aim of this review is to provide an updated summary version of the current Cochrane review on the surgical management of pelvic organ prolapse...
  42. ncbi Laparoscopic repair of incisional hernias
    William S Cobb
    Carolinas Laparoscopic and Advanced Surgery Program, Carolinas Medical Center, 1000 Blythe Boulevard, Charlotte, NC 28203, USA
    Surg Clin North Am 85:91-103, ix. 2005
    ....
  43. ncbi Prospective evaluation of adhesion characteristics to intraperitoneal mesh and adhesiolysis-related complications during laparoscopic re-exploration after prior ventral hernia repair
    Eric D Jenkins
    Department of Surgery, Section of Minimally Invasive Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8109, St Louis, MO 63110, USA
    Surg Endosc 24:3002-7. 2010
    ....
  44. pmc Herniorrhaphy with polypropylene mesh causing inguinal vasal obstruction: a preventable cause of obstructive azoospermia
    David Shin
    Division of Male Reproductive Medicine and Surgery, Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA
    Ann Surg 241:553-8. 2005
    ..To report a multiinstitutional experience of men presenting with infertility secondary to inguinal hernia repair using polypropylene mesh...
  45. pmc Histologic and biomechanical evaluation of a novel macroporous polytetrafluoroethylene knit mesh compared to lightweight and heavyweight polypropylene mesh in a porcine model of ventral incisional hernia repair
    L Melman
    Section of Minimally Invasive Surgery, Department of Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8109, St Louis, MO, USA
    Hernia 15:423-31. 2011
    ....
  46. ncbi Evaluation of adhesion formation and host tissue response to intra-abdominal polytetrafluoroethylene mesh and composite prosthetic mesh
    Brent D Matthews
    Department of Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Surg Res 123:227-34. 2005
    ....
  47. ncbi Open abdomen after trauma and abdominal sepsis: a strategy for management
    William P Schecter
    Department of Surgery, University of California, San Francisco, San Francisco, CA, USA
    J Am Coll Surg 203:390-6. 2006
  48. ncbi Comparing the behavior of different polypropylene meshes (heavy and lightweight) in an experimental model of ventral hernia repair
    J M Bellon
    Department of Surgery, Faculty of Medicine, Networking Research Center on Bioengineering, Biomaterials and Nanomedicine CIBER BBN, Alcala University, Alcala de Henares, Madrid, Spain
    J Biomed Mater Res B Appl Biomater 89:448-55. 2009
    ..Compared with HW, LW prostheses have the benefit that less foreign material was implanted, preserving the elasticity of the recipient host tissue...
  49. ncbi Intestinal perforation as a long-term complication of plug and mesh inguinal hernioplasty: case report
    M Benedetti
    Istituto di Chirurgia Generale e dei Trapianti d Organo Chirurgia Gastroenterologica e Mammaria, IRCCS Policlinico S Matteo Università degli Studi di Pavia, P le Golgi 2, 27100 Pavia, Italy
    Hernia 9:93-5. 2005
    ..We report on a case of sigmoid colon perforation due to a plug of Trabucco hernioplasty performed 2 years previously...
  50. ncbi Laparoscopic ventral hernia repair is safe and cost effective
    G Beldi
    Department of Visceral and Transplant Surgery, Inselspital University Bern, CH 3010 Bern, Switzerland
    Surg Endosc 20:92-5. 2006
    ..This study aimed to compare the early complications and cost effectiveness of open hernia repair with those associated with laparoscopic repair...
  51. ncbi Laparoscopic repair of abdominal intercostal hernia: a case report and review of the literature
    Mohamed A Kurer
    Department of Surgery, York Hospital, Wigginton Road, York, UK YO31 8HE
    Surg Laparosc Endosc Percutan Tech 16:270-1. 2006
    ..There were no peri-operative complications and the patient was asymptomatic on review 9 months later. We suggest that a laparoscopic approach may be used for treatment of an uncomplicated abdominal intercostal hernia...
  52. ncbi Mesh complications after prosthetic reinforcement of hiatal closure: a 28-case series
    Rudolf J Stadlhuber
    Department of Surgery, Creighton University School of Medicine, 601 N 30th Street, Suite 3740, Omaha, NE 68131 2197, USA
    Surg Endosc 23:1219-26. 2009
    ..This has lead to the use of mesh for crural repair, which has resulted in an improved recurrence rate (0-24%). However, mesh complications have been observed...
  53. ncbi Laparoscopic versus open ventral hernia repairs: 5 year recurrence rates
    Naveen Ballem
    Department of Surgery, Cleveland Clinic, 9500 Euclid Avenue, Crile A 80, Cleveland, OH 44195, USA
    Surg Endosc 22:1935-40. 2008
    ..There is scant data in the literature for this group of patients regarding longer follow-up. This study compares the actual 5 year recurrence rates of laparoscopic versus open techniques and determines factors that may affect recurrence...
  54. ncbi Lichtenstein inguinal hernioplasty using butyl-2-cyanoacrylate versus sutures. Preliminary experience of a prospective randomized trial
    W Nowobilski
    Department of General and Gastroenterological Surgery, St Vincent a Paulo Hospital of Gdynia, Gdynia, Poland
    Eur Surg Res 36:367-70. 2004
    ..The cost of sutures and tissue adhesive used in both procedures was comparable. The use of tissue adhesive in mesh fixation and wound closure seems to be a promising technique in Lichtenstein hernia repair...
  55. ncbi Polyvinylidene fluoride: a suitable mesh material for laparoscopic incisional and parastomal hernia repair! A prospective, observational study with 344 patients
    D Berger
    Department of Surgery, Stadtklinik, Balgerstrasse 50, 76532 Baden Baden, Germany
    Hernia 13:167-72. 2009
    ..Today, the laparoscopic approach is a standard procedure for the repair of incisional hernias. However, the direct contact of visceral organs with mesh material is a major issue...
  56. ncbi New polymer for intra-abdominal meshes--PVDF copolymer
    Joachim Conze
    Department of Surgery, Rheinish Westphalian Technical University, D 52074 Aachen
    J Biomed Mater Res B Appl Biomater 87:321-8. 2008
    ..The results were compared with a matching polypropylene (PP) mesh...
  57. ncbi Resection of sternal tumors and reconstruction of the thorax: a review of 15 patients
    Shuji Haraguchi
    Department of Surgery, Nippon Medical School Second Hospital, 1 396 Kosugi cho, Nakahara ku, Kawasaki, Kanagawa, 211 8533, Japan
    Surg Today 36:225-9. 2006
    ..We report our experience of resecting sternal tumors, followed by reconstruction of the skeletal and soft-tissue defects, and discuss the usefulness of sandwiched Marlex and stainless-steel mesh...
  58. ncbi Long-term results of hiatal hernia mesh repair and antireflux laparoscopic surgery
    E Soricelli
    La Sapienza University, Paride Stefanini, Rome, Italy
    Surg Endosc 23:2499-504. 2009
    ..This study retrospectively evaluated the long-term results of LARS with or without the use of a mesh in a series of patients treated from 1992 to 2007...
  59. ncbi Tension-free repair of hiatal hernia during laparoscopic fundoplication: a ten-year experience
    P V Gryska
    Department of Surgery, Newton Wellesley Hospital, Newton, MA 02462, USA
    Hernia 9:150-5. 2005
    ..The use of prosthetic material at the esophageal hiatus to strengthen the crural repair is relatively new and questions remain. This report examines the safety and efficacy of a tension-free crural repair with mesh...
  60. pmc Seroma and recurrence in laparoscopic ventral hernioplasty
    Evangelos C Tsimoyiannis
    Department of Surgery, G Hatzikosta General Hospital, Ioannina, Greece
    JSLS 12:51-7. 2008
    ..The aim of this study was to investigate the events, what caused recurrences, and the technique to prevent recurrence in laparoscopic ventral hernioplasty...
  61. pmc Inguinal hernias
    John T Jenkins
    University Department of Surgery, Western Infirmary, Glasgow G11 6NT
    BMJ 336:269-72. 2008
  62. ncbi Differences in polypropylene shrinkage depending on mesh position in an experimental study
    Miguel Angel García-Ureña
    Department of Surgery, Cadiz University School of Medicine, Cra Nacional IV, Km 665, 11510 Puerto Real, Spain
    Am J Surg 193:538-42. 2007
    ..Polypropylene (PP) mesh is one of the most frequent materials used in hernia repair. We have experimentally evaluated the shrinkage of PP mesh depending on the place of implantation...
  63. ncbi Perioperative morbidity using transvaginal mesh in pelvic organ prolapse repair
    Daniel Altman
    Division of Obstetrics and Gynecology, Karolinska Institutet Danderyd Hospital, 182 88 Stockholm, Sweden
    Obstet Gynecol 109:303-8. 2007
    ..To describe the perioperative morbidity associated with transvaginal mesh repair of pelvic organ prolapse...
  64. ncbi Open inguinal hernia repair with the use of a polyglycolic acid-trimethylene carbonate absorbable mesh: a pilot study
    M Efthimiou
    Department of General Surgery, University Hospital of Larissa, Mezourlo, Larissa, Greece
    Hernia 15:181-4. 2011
    ..Traditionally, non absorbable materials have been used for mesh manufacture. The purpose of this pilot study was to evaluate the efficacy of using a totally absorbable prosthetic mesh for open inguinal hernia repair...
  65. ncbi Anisotropic evaluation of synthetic surgical meshes
    E R Saberski
    University of Connecticut School of Medicine, Farmington, Connecticut, USA
    Hernia 15:47-52. 2011
    ..Haphazard orientation of anisotropic mesh material can contribute to inconsistent surgical outcomes. We aimed to characterize and compare anisotropic properties of commonly used synthetic meshes...
  66. ncbi Sutureless Lichtenstein: first results of a prospective randomised clinical trial
    Christian Helbling
    Klinik für Chirurgie Kantonsspital Aarau, Buchserstrasse, Switzerland
    Hernia 7:80-4. 2003
    ..The results in group 2 were excellent, and there was no difference vs group 1. Furthermore, there was a tendency for better results in group 2. These results are very promising and justify a continuation of the study...
  67. ncbi Shouldice technique versus other open techniques for inguinal hernia repair
    Bruno Amato
    Dipartimento di Chirurgia Generale Edif 6, Universita Degli Studi Di Napoli, Napoli
    Cochrane Database Syst Rev 4:CD001543. 2012
    ..Outcome measures, such as recurrence rates, complications and length of post operative stay, vary considerably among the various techniques...
  68. ncbi Mesh implants in hernia repair. Inflammatory cell response in a rat model
    R Rosch
    Department of Surgery, RWTH Aachen University, Aachen, Germany
    Eur Surg Res 35:161-6. 2003
    ..To approach biocompatibility of surgical meshes we therefore examined the infiltrate of these cells as well as the proliferation rate in response to different clinically applied materials...
  69. pmc Laparoscopic repair of left lumbar hernia after laparoscopic left nephrectomy
    Michel Gagner
    Herbert Wertheim College of Medicine, Florida International University, Department of Surgery, Miami, Florida, PO Box 336 H, Scarsdale, NY 10583, USA
    JSLS 14:405-9. 2010
    ..A review of the literature on this infrequent operation is presented. Laparoscopic repair of lumbar hernias has all the advantages of laparoscopic ventral hernia repair...
  70. pmc The transinguinal preperitoneal hernia correction vs Lichtenstein's technique; is TIPP top?
    G G Koning
    Department of Surgery, St Elisabeth Hospital, Hilvarenbeekseweg 60, 5055 GC Tilburg, The Netherlands
    Hernia 15:19-22. 2011
    ..The aim of this study was to evaluate 3 years of TIPP and Lichtenstein experience since the start of our Hernia Center Brabant in January 2006...
  71. ncbi Patient satisfaction, chronic pain, and quality of life after elective incisional hernia repair: effects of recurrence and repair technique
    C W Snyder
    Section of Gastrointestinal Surgery, Department of Surgery, University of Alabama at Birmingham, 1922 7th Avenue South, KB 428, Birmingham, AL 35294 0016, USA
    Hernia 15:123-9. 2011
    ..To determine the effects of repair technique and hernia recurrence on patient-reported outcomes after incisional hernia repair...
  72. ncbi Amyand hernia repaired with Bio-A: a case report and review
    Pamela L Burgess
    Dwight David Eisenhower Army Medical Center, Ft Gordon, Georgia 30905, USA
    J Surg Educ 68:62-6. 2011
    ....
  73. ncbi Comparing the effects of Bassini versus tension-free hernioplasty: 3 years' follow-up
    Yulong Shi
    Division of Gastrointestinal Surgery, Affiliated Provincial Hospital of Shandong University, Jinwu Road 324, Jinan, 250021, China
    Front Med China 4:463-8. 2010
    ....
  74. ncbi Surgical management of pelvic organ prolapse in women
    Christopher Maher
    Wesley Urogynaecology Unit, Wesley Hospital, Sandford Jackson Building Level 4, Suite 86, 30 Chasely Street, Auchenflower, Queensland, Australia, 4066
    Cochrane Database Syst Rev 4:CD004014. 2010
    ..Adequately powered randomised controlled clinical trials are urgently needed on a wide variety of issues and particularly need to include women's perceptions of prolapse symptoms...
  75. ncbi Prevention of parastomal herniation with biologic/composite prosthetic mesh: a systematic review and meta-analysis of randomized controlled trials
    Sanjaya Prabhath Wijeyekoon
    Academic Surgical Unit, Barts and the London School of Medicine and Dentistry, Whitechapel, London, United Kingdom
    J Am Coll Surg 211:637-45. 2010
    ..A systematic review with meta-analysis of randomized clinical trials was performed to determine the benefits and risks of mesh reinforcement versus conventional stoma formation in preventing parastomal herniation...
  76. ncbi Disability and chronic pain after open mesh and laparoscopic inguinal hernia repair
    Michael Bozuk
    Department of Surgery, Cottage Hospital, Santa Barbara, California 93102, USA
    Am Surg 69:839-41. 2003
    ..In addition, we found that this procedure did not interfere with return to work at 6 months or return to daily activities in either the laparoscopic or open repair group...
  77. ncbi Surgical management of pelvic organ prolapse in women: a short version Cochrane review
    C Maher
    Neurourol Urodyn 27:3-12. 2008
    ..Pelvic organ prolapse may occur in up to 50% of parous women. A variety of urinary, bowel and sexual symptoms may be associated with prolapse...
  78. ncbi Textile analysis of heavy weight, mid-weight, and light weight polypropylene mesh in a porcine ventral hernia model
    William S Cobb
    Department of General Surgery, Carolinas Laparoscopic and Advanced Surgery Program, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
    J Surg Res 136:1-7. 2006
    ..The purpose of this study was to assess the burst strength and stiffness of heavy weight (HW), mid-weight (MW), and light weight (LW) polypropylene mesh pre-implantation and 5 months post-implantation in a porcine ventral hernia model...
  79. pmc The effect of bacterial infection on the biomechanical properties of biological mesh in a rat model
    Charles F Bellows
    Department of Surgery, Tulane University Health Sciences Center, New Orleans, Louisiana, United States of America
    PLoS ONE 6:e21228. 2011
    ..However, failure rates and infections of these materials persist clinically. The purpose of this study was to determine the mechanical properties of biologic mesh in response to a bacterial encounter...
  80. ncbi Cyanoacrylate tissue sealant impairs tissue integration of macroporous mesh in experimental hernia repair
    R H Fortelny
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria Research Center for Traumatology of AUVA, Donaveschingenstr 13, 1200, Vienna, Austria
    Surg Endosc 21:1781-5. 2007
    ..The beneficial effects of fibrin sealant have been reported in both experimental and clinical hernia repair. However, data on cyanoacrylate glues for mesh sealing are limited...
  81. ncbi Laparoscopic ventral/incisional hernia repair: a single centre experience of 1,242 patients over a period of 13 years
    A Sharma
    Max Institute of Minimal Access, Metabolic and Bariatric Surgery, A unit of Devki Devi Foundation, Max Super Speciality Hospital, East Block, 2, Press Enclave Road, Saket, New Delhi, 110 017, India
    Hernia 15:131-9. 2011
    ..However several issues such as optimal fixation technique, occult hernias, management of inadvertent enterotomies, postoperative seromas and recurrence require appraisal...
  82. ncbi A single-surgeon randomized trial comparing three composite meshes on chronic pain after Lichtenstein hernia repair in local anesthesia
    H Paajanen
    Department of General Surgery, The Central Hospital of Mikkeli, Porrassalmenkatu 35 37, 50100 Mikkeli, Finland
    Hernia 11:335-9. 2007
    ..Chronic pain may be a long-term problem related to operative trauma and mesh material in Lichtenstein hernioplasty...
  83. ncbi Laparoscopic sacral colpopexy with Gynemesh as graft material--experience and results
    Neena Agarwala
    University of Nebraska Medical Center, Omaha, Nebraska 68198, USA
    J Minim Invasive Gynecol 14:577-83. 2007
    ..To evaluate the safety and efficacy of Prolene (Ethicon, Inc., Johnson and Johnson, Somerville, NJ) graft for sacral colpopexy and ease of use laparoscopically...
  84. pmc Use of biological meshes for abdominal wall reconstruction in highly contaminated fields
    Andrea Cavallaro
    General Surgery and Senology, Department of Surgery, Policlinico Vittorio Emanuele Hospital, University of Catania Medical School, Via S Sofia 78, 95123 Catania, Italy
    World J Gastroenterol 16:1928-33. 2010
    ..Bovine pericardium graft was placed in the retrorectus space and secured to the anterior abdominal wall using polypropylene sutures in a tension-free manner. We experienced no evidence of recurrence at 4 and 5 years follow-up...
  85. ncbi Laparoscopic repair of parastomal hernias with a modified Sugarbaker technique
    F Muysoms
    Department of Surgery, AZ Maria Middelares, Gent, Belgium
    Acta Chir Belg 107:476-80. 2007
    ..With the increasing experience in laparoscopic ventral and incisonal hernia repair this minimal invasive technique has also been used to repair parastomal hernias. Different types of laparoscopic repair have been described...
  86. ncbi Comparison of cross-linked and non-cross-linked porcine acellular dermal matrices for ventral hernia repair
    Charles E Butler
    Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    J Am Coll Surg 211:368-76. 2010
    ..The newer non-cross-linked PADMs, however, have not been directly compared with cross-linked PADMs. We hypothesized that chemical cross-linking affects the biologic host response to PADMs used to repair ventral hernias...
  87. ncbi Comparison of recurrence with lightweight composite polypropylene mesh and heavyweight mesh in laparoscopic totally extraperitoneal inguinal hernia repair: an audit of 1,232 repairs
    D Akolekar
    Department of Surgery, Royal Infirmary Edinburgh, 51, Little France Crescent, Edinburgh, EH16 4SA, UK
    Hernia 12:39-43. 2008
    ..The aim of this study was to compare the outcome following the use of a new lightweight vs a standard heavyweight mesh during TEP hernia repair...
  88. ncbi Relationship between tissue ingrowth and mesh contraction
    Rodrigo Gonzalez
    Department of Surgery, Emory Endosurgery Unit and Hernia Institute, Emory University School of Medicine, 1364 Clifton Road NE, Atlanta, Georgia 30322, USA
    World J Surg 29:1038-43. 2005
    ..PE resulted in less contraction than polypropylene. A strong integration of the mesh into the tissue helps prevent this phenomenon, which is evidenced by a significant correlation between tissue ingrowth force and mesh size...
  89. pmc Defining success after surgery for pelvic organ prolapse
    Matthew D Barber
    Obstetrics, Gynecology, and Women s Health Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Obstet Gynecol 114:600-9. 2009
    ..To describe pelvic organ prolapse surgical success rates using a variety of definitions with differing requirements for anatomic, symptomatic, or re-treatment outcomes...
  90. ncbi The Lichtenstein repair in 2002: an overview of causes of recurrence after Lichtenstein tension-free hernioplasty
    P K Amid
    Lichtenstein Hernia Institute, 5901 W Olympic Boulevard, Suite 207, Los Angeles, CA 90036, USA
    Hernia 7:13-6. 2003
    ..Following the key principles of the Lichtenstein tension-free hernioplasty, which can be facilitated by using a recently developed prosthesis that addresses all the key principles of the procedure, achieves the best result...
  91. ncbi Technique and outcomes of abdominal incisional hernia repair using a synthetic composite mesh: a report of 455 cases
    David A Iannitti
    Division of Gastrointestinal and Minimally Invasive Surgery, Carolinas Medical Center, Charlotte, NC 28203, USA
    J Am Coll Surg 206:83-8. 2008
    ..Several different surgical techniques and types of mesh prosthetics are available for repair. We evaluated outcomes of an open ventral hernia repair using a synthetic composite mesh...
  92. ncbi [TAPP versus TEP: a retrospective analysis 5 years after laparoscopic transperitoneal and total endoscopic extraperitoneal repair in inguinal and femoral hernia]
    A Czechowski
    Chirurgische Klinik, Städtisches Klinikum Lüneburg
    Chirurg 74:1143-9. 2003
    ..The 5-year results after laparoscopic repair of inguinal and femoral hernias with the TAPP and TEP techniques were analyzed...
  93. pmc Vaginal repair with mesh versus colporrhaphy for prolapse: a randomised controlled trial
    M Carey
    Department of Urogynaecology, Royal Women s Hospital, Melbourne, Vic, Australia
    BJOG 116:1380-6. 2009
    ..To compare vaginal repair augmented by mesh with traditional colporrhaphy for the treatment of pelvic organ prolapse...
  94. ncbi Endoscopic removal of intravesical polypropylene sling with the holmium laser
    Marc Hodroff
    Center for Continence Care at Metropolitan Urologic Specialists, St Paul, Minnesota, USA
    J Urol 172:1361-2. 2004
  95. ncbi Polypropylene meshes to prevent abdominal herniation. Can stable coatings prevent adhesions in the long term?
    Pieter J Emans
    Department of General Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands
    Ann Biomed Eng 37:410-8. 2009
    ..The data indicate that long-term protection of implanted meshes against excessive adhesions may be achieved through stable biocompatible hydrogel surface coatings...
  96. pmc Influence of preservation versus division of ilioinguinal, iliohypogastric, and genital nerves during open mesh herniorrhaphy: prospective multicentric study of chronic pain
    Sergio Alfieri
    Department of Digestive Surgery, Catholic University of Sacred Heart, Roma, Italy
    Ann Surg 243:553-8. 2006
    ..To evaluate whether the various surgical treatment reserved for ilioinguinal, iliohypogastric, and genital branch of the genitofemoral nerves, during open hernia mesh repair, is effective in reducing chronic postoperative pain...
  97. ncbi Mechanical properties of urogynecologic implant materials
    H P Dietz
    Royal Hospital for Women, New South Wales, Australia
    Int Urogynecol J Pelvic Floor Dysfunct 14:239-43; discussion 243. 2003
    ..83 N/mm. We concluded that the TVT and other wide-weave Prolene tapes have unique biomechanical characteristics. These properties may be at least partly responsible for the apparent clinical success of the implants...
  98. ncbi Multicentre prospective study of fascial closure rate after open abdomen with vacuum and mesh-mediated fascial traction
    S Acosta
    Vascular Centre, Skane University Hospital, Lund University, Malmo, Sweden
    Br J Surg 98:735-43. 2011
    ..The main objective of this study was to evaluate the fascial closure rate in patients after vacuum-assisted wound closure and mesh-mediated fascial traction (VAWCM) for long-term OA treatment, and to describe complications...
  99. ncbi Graft use in transvaginal pelvic organ prolapse repair: a systematic review
    Vivian W Sung
    Alpert Medical School at Brown University, Women and Infants Hospital, Providence, Rhode Island 02903, USA
    Obstet Gynecol 112:1131-42. 2008
    ..To estimate the anatomic and symptomatic efficacy of graft use in transvaginal prolapse repair and to estimate the rates and describe the spectrum of adverse events associated with graft use...
  100. ncbi Practical experience with the Stoppa repair of ventral/incisional hernias
    G Veillette
    University of Connecticut School of Medicine, Farmington, USA
    Conn Med 65:67-70. 2001
    ..In such repairs it achieves a recurrence rate comparable to that achieved by other mesh techniques for less complex hernias...
  101. ncbi Causes, prevention, and surgical treatment of postherniorrhaphy neuropathic inguinodynia: triple neurectomy with proximal end implantation
    P K Amid
    Lichtenstein Hernia Institute, 5901 W Olympic Boulevard Suite 207, Los Angeles, CA 90036, USA
    Hernia 8:343-9. 2004
    ..A one-stage surgical procedure resecting all three nerves from an anterior approach avoids a second operation through the flank and successfully treats chronic neuralgia...

Research Grants38

  1. A New Surgical Mesh for Pelvic Floor Reconstruction
    Simon Williams; Fiscal Year: 2005
    The objective of this research is to determine the feasibility of developing a new absorbable surgical mesh for pelvic floor reconstruction...
  2. Assessment of Tissue Response to Stress
    Joan Sanders; Fiscal Year: 2006
    ..this technology could be applied to other areas of rehabilitation, for example, shoe design for patients with insensate feet, cushion design for wheelchair users, and mattress design for bedridden patients [unreadable] [unreadable]..
  3. Core-Shell Fiber Mesh for the Treatment of UI and PFD in Elderly Women
    MICHAEL P H LAU; Fiscal Year: 2011
    DESCRIPTION (provided by applicant): This phase I SBIR application investigates the feasibility of using surgical mesh composed of novel timed-release fibers to controllably contract and provide support to pelvic organs with the long ..
  4. Development of a Novel Composite Surgical Mesh
    David J Vachon; Fiscal Year: 2012
    ....
  5. Biodegradable Drug-Eluting Surgical Meshes with Tunable Release Kinetics
    JOHN JOHN SCHWARTZ; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): We have developed and are optimizing a prototype drug-eluting surgical mesh comprised of novel copolymer blends for controlled locoregional delivery of chemotherapy to prevent local colorectal tumor ..
  6. Biopolymer fiber as a bioabsorbable monofilament suture
    David Martin; Fiscal Year: 2002
    ..abstract_text> ..
  7. Biopolymer fiber as a bioabsorbable monofilament suture
    David Martin; Fiscal Year: 2005
    ....
  8. Natural History of POP-- A Prospective Cohort Study
    Ingrid Nygaard; Fiscal Year: 2005
    ..The national cost burden is large. This project will provide fundamental data to guide future decisions about intervention threshold, preventative measures, and risk factor modification. ..
  9. INTERFACE MECHANICS, MATERIALS AND TISSUE RESPONSE
    Joan Sanders; Fiscal Year: 2007
    ..The development of methods to predict and overcome the detrimental effects of residual limb shape change and ultimately prevent soft-tissue breakdown will help to prevent secondary disability and morbidity in the amputee population. ..
  10. Skin Adaptation to Mechanical Stress
    Joan Sanders; Fiscal Year: 2006
    ..By understanding the process of skin adaptation (natural skin strengthening) at both a cellular and molecular level, therapies to encourage skin adaptation before breakdown occurs can be intelligently pursued. ..
  11. INTERFACE MECHANICS, MATERIALS, AND TISSUE RESPONSE
    Joan Sanders; Fiscal Year: 2003
    ....
  12. INTERFACE MECHANICS, MATERIALS, AND TISSUE RESPONSE
    Joan Sanders; Fiscal Year: 2002
    ....
  13. NEW BIOMATERIALS TO MINIMIZE SCAR TISSUE FORMATION
    Joan Sanders; Fiscal Year: 2002
    ..e. soft-tissue complications that require surgical repair through use of a biomaterial. The new materials will prevent scar tissue formation and reduce the occurrence of secondary complications. ..
  14. Function of the Urethra in Continent Women
    Kimberly Kenton; Fiscal Year: 2008
    ..Normative ranges will be calculated for EMG, current perception thresholds, and urethral pressures for Caucasian and African American women. These data can then be used by other centers as reference data. [unreadable] [unreadable]..
  15. Conference--National Urology Resident Female Pelvic Med
    Firouz Daneshgari; Fiscal Year: 2006
    ..abstract_text> ..
  16. Mechanobiology and Regenerative Medicine
    Michael S Sacks; Fiscal Year: 2010
    ..A timeline for completion of these studies, hypotheses to drive the specific aims, alternative approaches for completion of the work, and quantitative criteria for success are provided. ..
  17. Cell Recruitment Induced by ECM Scaffold Degradation
    Stephen F Badylak; Fiscal Year: 2010
    ..The objectives of the studies, the hypothesis upon which the experimental design is based, and a timeline for completion of the studies are presented. ..
  18. ORIGIN OF CELLS THAT REPOPULATE RESORBABLE ECM SCAFFOLDS
    Stephen Badylak; Fiscal Year: 2003
    ..abstract_text> ..
  19. LIPOPROTEINS MODULATE THE HEPATIC RESPONSE TO ENDOTOXIN
    Hobart Harris; Fiscal Year: 2008
    ..abstract_text> ..
  20. Mechanisms of Vaginal Sling Effects on Continence
    Firouz Daneshgari; Fiscal Year: 2006
    ..The long-term goal of this proposal is to expand the findings of this project into an R01 application in order to translate our findings into relevant clinical studies. [unreadable] [unreadable]..
  21. ADIPOSE DERIVED STEM CELLS FOR TREATMENT OF INCONTINENCE
    LARISSA RODRIGUEZ; Fiscal Year: 2008
    ..Lastly, we will use an animal model of incontinence and decreased urethral resistance to test the hypothesis that these cells can be used to reconstruct a functional urethra as a treatment of stress incontinence. ..
  22. Cellular Remodeling of ECM Scaffolds
    Stephen Badylak; Fiscal Year: 2009
    ..We have identified clearly defined specific aims with quantifiable end points and an efficient three year timeline to conduct this work. ..
  23. ORIGIN OF CELLS THAT REPOPULATE RESORBABLE ECM SCAFFOLDS
    Stephen Badylak; Fiscal Year: 2001
    ..abstract_text> ..
  24. Mechanisms of ECM Scaffold Remodeling
    Stephen Badylak; Fiscal Year: 2006
    ..The work will be conducted by an experienced interdisciplinary team of scientists and a timeline is presented for completion of the work. ..
  25. Effect of vertebral endplate composition on disc health
    Frank Acosta; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  26. Modified Late Infarct Reperfusion to Prevent Post MI CHF
    Robert Gorman; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  27. Regulation of Fibroblast Survival in the Collagen Matrix
    Mark Carlson; Fiscal Year: 2005
    ..Loss of matrix anchorage is hypothesized to reverse these effects and induce apoptosis. The involvement of each protein will be probed with mutated isoforms. ..
  28. Treatment Investigation for Posterior Prolapse
    GEOFFREY CUNDIFF; Fiscal Year: 2005
    ..All subjects will be followed for a total of three years. ..
  29. Advancing Clinical Research in Pediatric Surgery
    KEVIN LALLY; Fiscal Year: 2006
    ..Lally with his research and mentoring to advance the quality of clinical research in pediatric surgery, develop an expanded international trials network, and improve the outcome of high-risk infants. ..
  30. PKC ALTERATIONS IN LUT DYSFUNCTION
    Firouz Daneshgari; Fiscal Year: 2004
    ..abstract_text> ..
  31. Pittsburgh Collab Reconstructive Pelvic Surgery Program
    Halina Zyczynski; Fiscal Year: 2005
    ..The surgical team is proficient in both surgical approaches and comfortable with the concept of a randomized surgical trial. ..
  32. Assessment of Altered Function in Diabetic Bladder
    Firouz Daneshgari; Fiscal Year: 2005
    ....
  33. Volume-Outcomes in Incontinence Surgery
    Jennifer Anger; Fiscal Year: 2005
    ..The primary outcome will be re-operation rates, repeat sling procedures (for failures), and other postoperative complications, stratified by high and low volume surgeons and hospitals. ..
  34. Bariatric Surgery Outcome/Cost in Medicare Beneficiaries
    David Flum; Fiscal Year: 2006
    ..3. Perform a modeled cost effectiveness analysis of bariatric procedures compared to non-surgical approaches. ..
  35. URINE LOSS AND PROLAPSE IN NUNS AND THEIR PAROUS SISTERS
    GUNHILDE BUCHSBAUM; Fiscal Year: 2003
    ..A matched pair logistic regression will be performed to obtain an adjusted estimate of the impact of familiality and vaginal delivery in UT and POP, taking into account other risk factors. ..
  36. MOLECULAR AND BIOCHEMICAL STUDY OF COLLAGEN IN PROLAPSE
    Anthony Visco; Fiscal Year: 2002
    ..This study would be the first large-scale comprehensive description of collagen cross-linking, lysine hydroxylation, and of genes coding for enzymes involved in the cross-linking process, in patients with pelvic organ prolapse. ..
  37. BOTULINUM TOXIN THERAPY FOR INTERSTITIAL CYSTITIS/CHRON*
    Mary FitzGerald; Fiscal Year: 2007
    ..abstract_text> ..
  38. Sensory Testing in Subjects with Interstitial Cystitis
    Mary FitzGerald; Fiscal Year: 2004
    ..abstract_text> ..