breast implants

Summary

Summary: Implants used to reconstruct and/or cosmetically enhance the female breast. They have an outer shell or envelope of silicone elastomer and are filled with either saline or silicone gel. The outer shell may be either smooth or textured.

Top Publications

  1. ncbi Infection in breast implants
    Brigitte Pittet
    Plastic and Reconstructive Surgery Unit, Department of Surgery, University of Geneva Hospitals, Geneva, Switzerland
    Lancet Infect Dis 5:94-106. 2005
  2. ncbi Sonication of removed breast implants for improved detection of subclinical infection
    U M Rieger
    Department of Plastic, Reconstructive, and Aesthetic Surgery, University Hospital of Basel, Spitalstrasse 21, 4031, Basel, Switzerland
    Aesthetic Plast Surg 33:404-8. 2009
  3. ncbi Comparison of implant-based immediate breast reconstruction with and without acellular dermal matrix
    Andrew J Vardanian
    Division of Plastic and Reconstructive Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    Plast Reconstr Surg 128:403e-410e. 2011
  4. ncbi Surface modification of silicone breast implants by binding the antifibrotic drug halofuginone reduces capsular fibrosis
    Philip H Zeplin
    Department of Trauma, Hand, Plastic, and Reconstructive Surgery, University Hospital Wuerzburg, Wuerzburg, Germany
    Plast Reconstr Surg 126:266-74. 2010
  5. ncbi Detection of subclinical infection in significant breast implant capsules
    Aniko Pajkos
    Department of Infectious Diseases, University of Sydney, Australia
    Plast Reconstr Surg 111:1605-11. 2003
  6. pmc Pilot study of association of bacteria on breast implants with capsular contracture
    Jose L del Pozo
    Division of Clinical Microbiology and Infectious Diseases, Mayo Clinic, Rochester, MN 55905, USA
    J Clin Microbiol 47:1333-7. 2009
  7. ncbi Bacterial biofilms and capsular contracture in patients with breast implants
    U M Rieger
    Department of Plastic, Reconstructive and Aesthetic Surgery, Medical University, Innsbruck, Austria
    Br J Surg 100:768-74. 2013
  8. ncbi The use of acellular dermal matrix in immediate two-stage tissue expander breast reconstruction
    Katie E Weichman
    New York University Langone Medical Center, Institute of Reconstructive Plastic Surgery, New York, NY, USA
    Plast Reconstr Surg 129:1049-58. 2012
  9. ncbi Infectious complications following breast reconstruction with expanders and implants
    Maurice Y Nahabedian
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Plast Reconstr Surg 112:467-76. 2003
  10. ncbi Acellular dermis-assisted breast reconstruction
    S L Spear
    Department of Plastic Surgery, Georgetown University, 1st Floor PHC Building, 3800 Reservoir Road NW, Washington, DC 20007, USA
    Aesthetic Plast Surg 32:418-25. 2008

Research Grants

  1. Stem Cell Based Soft Tissue Reconstruction
    Jeremy J Mao; Fiscal Year: 2010
  2. Novel Translucent Nanocomposite Biomaterials
    Judit E Puskas; Fiscal Year: 2010
  3. COX-2 Mediated Vascular Toxicity of Methylenedianiline
    TAMMY DUGAS; Fiscal Year: 2003
  4. PET Imaging of Breast Cancer via Sigma-2 Receptors
    Robert Mach; Fiscal Year: 2006
  5. PET Imaging of Breast Cancer via Sigma-2 Receptors
    Robert Mach; Fiscal Year: 2003
  6. IMMOBILIZATION OF ANTIMICROBIAL PEPTIDES
    LISE DURAN; Fiscal Year: 1992
  7. Microarray Analysis of Wounds
    AMY COLWELL; Fiscal Year: 2004
  8. Obesity, Body Image and Weight Maintenance
    DAVID SARWER; Fiscal Year: 2005
  9. 3D Adipose Tissue Generation and Functional Verification
    Charles Patrick; Fiscal Year: 2004
  10. Changes in sexual function following bariatric surgery
    DAVID SARWER; Fiscal Year: 2009

Detail Information

Publications207 found, 100 shown here

  1. ncbi Infection in breast implants
    Brigitte Pittet
    Plastic and Reconstructive Surgery Unit, Department of Surgery, University of Geneva Hospitals, Geneva, Switzerland
    Lancet Infect Dis 5:94-106. 2005
    ..The current hypothesis of the possible role of low-grade or subclinical infection in the origin of capsular contracture is also reviewed...
  2. ncbi Sonication of removed breast implants for improved detection of subclinical infection
    U M Rieger
    Department of Plastic, Reconstructive, and Aesthetic Surgery, University Hospital of Basel, Spitalstrasse 21, 4031, Basel, Switzerland
    Aesthetic Plast Surg 33:404-8. 2009
    ..Current diagnostic tests consist of intraoperative swabs and tissue biopsies. Sonication of removed implants may improve the diagnosis of implant infection by detachment of biofilms from the implant surface...
  3. ncbi Comparison of implant-based immediate breast reconstruction with and without acellular dermal matrix
    Andrew J Vardanian
    Division of Plastic and Reconstructive Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    Plast Reconstr Surg 128:403e-410e. 2011
    ..Its performance profile remains equivocal. The authors studied whether adding it in implant-based immediate breast reconstruction improved outcomes when compared with non-acellular dermal matrix reconstruction...
  4. ncbi Surface modification of silicone breast implants by binding the antifibrotic drug halofuginone reduces capsular fibrosis
    Philip H Zeplin
    Department of Trauma, Hand, Plastic, and Reconstructive Surgery, University Hospital Wuerzburg, Wuerzburg, Germany
    Plast Reconstr Surg 126:266-74. 2010
    Capsular fibrosis is one of the most severe complications that can occur in connection with silicone breast implants. Should this case arise, a periprosthetic deposition of fibroid tissue may evolve...
  5. ncbi Detection of subclinical infection in significant breast implant capsules
    Aniko Pajkos
    Department of Infectious Diseases, University of Sydney, Australia
    Plast Reconstr Surg 111:1605-11. 2003
    ..significant capsular contracture was conducted to investigate the association of biofilm contamination, breast implants, and capsular contracture...
  6. pmc Pilot study of association of bacteria on breast implants with capsular contracture
    Jose L del Pozo
    Division of Clinical Microbiology and Infectious Diseases, Mayo Clinic, Rochester, MN 55905, USA
    J Clin Microbiol 47:1333-7. 2009
    ..aim of this prospective observational pilot study was to test the hypothesis that the presence of bacteria on breast implants is associated with capsular contracture...
  7. ncbi Bacterial biofilms and capsular contracture in patients with breast implants
    U M Rieger
    Department of Plastic, Reconstructive and Aesthetic Surgery, Medical University, Innsbruck, Austria
    Br J Surg 100:768-74. 2013
    It has been hypothesized that bacterial biofilms on breast implants may cause chronic inflammation leading to capsular contracture. The association between bacterial biofilms of removed implants and capsular contracture was investigated.
  8. ncbi The use of acellular dermal matrix in immediate two-stage tissue expander breast reconstruction
    Katie E Weichman
    New York University Langone Medical Center, Institute of Reconstructive Plastic Surgery, New York, NY, USA
    Plast Reconstr Surg 129:1049-58. 2012
    ..This study was performed to analyze complications associated with its use in immediate two-stage, implant-based breast reconstruction and to subsequently develop guidelines for its use...
  9. ncbi Infectious complications following breast reconstruction with expanders and implants
    Maurice Y Nahabedian
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Plast Reconstr Surg 112:467-76. 2003
    ..29 times higher than when no lymph nodes were removed. No significant association between implant infection and age, diabetes, tobacco use, tumor stage, timing of implant insertion, or chemotherapy was found...
  10. ncbi Acellular dermis-assisted breast reconstruction
    S L Spear
    Department of Plastic Surgery, Georgetown University, 1st Floor PHC Building, 3800 Reservoir Road NW, Washington, DC 20007, USA
    Aesthetic Plast Surg 32:418-25. 2008
    ..This study aimed to examine the safety and efficacy of an acellular dermal sling in providing inferolateral support to the device during immediate breast reconstruction and expansion...
  11. ncbi Clinical and morphological conditions in capsular contracture formed around silicone breast implants
    Lukas Prantl
    Department of Plastic Surgery, University Hospital Regensburg, Regensburg, Germany
    Plast Reconstr Surg 120:275-84. 2007
    A study was performed to investigate histological changes in capsules formed around silicone breast implants and their correlation with the clinical classification of capsular contracture defined by the Baker score...
  12. ncbi Use of the acellular dermal matrix in revisionary aesthetic breast surgery
    G Patrick Maxwell
    Department of Plastic Surgery, Loma Linda University Medical Center, Loma Linda, CA 92354, USA
    Aesthet Surg J 29:485-93. 2009
    ..In these cases, surgeons are faced with either thinned breast tissues resulting from large breast implants with tissue stretch or encapsulation caused by excessive scarring...
  13. ncbi Breast implant research: where we have been, where we are, where we need to go
    V L Young
    Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St. Louis, Missouri, USA
    Clin Plast Surg 28:451-83, vi. 2001
    This article summarizes the current state and future needs of research into saline-filled and silicone gel breast implants. The authors describe recent investigations into possible causes and potential risk factors for silicone gel and ..
  14. ncbi In vitro analysis of modified surfaces of silicone breast implants
    W Siggelkow
    Department of Obstetrics and Gynecology, University of Aachen, Germany
    Int J Artif Organs 27:1100-8. 2004
    Although silicone breast implants are well tolerated, local complications such as capsular contracture occur because of insufficient integration with surrounding tissues...
  15. pmc Induction of hypergammaglobulinemia and macrophage activation by silicone gels and oils in female A.SW mice
    J O Naim
    Departments of Surgery, Rochester General Hospital, Rochester, New York 14621, USA
    Clin Diagn Lab Immunol 7:366-70. 2000
    ..epidemiological studies have found little evidence of systemic autoimmune disease associated with silicone breast implants, there still remains a question of whether silicones can cause local and/or systemic immune dysfunction...
  16. ncbi Breast augmentation using the spectrum implant with exteriorized injection domes
    Hilton Becker
    Boca Raton Community Hospital, Boca Raton Outpatient Surgery and Laser Center, Boca Raton, Fla, USA
    Plast Reconstr Surg 114:1617-20; discussion 1621. 2004
    ..Domes were exteriorized for 1 to 5 days to allow the implant volume to be altered in the early postoperative period. Thirty-three patients were treated without any infections...
  17. ncbi Difficulties with subpectoral augmentation mammaplasty and its correction: the role of subglandular site change in revision aesthetic breast surgery
    Malcolm A Lesavoy
    Division of Plastic Surgery, University of California, Los Angeles Medical Center, USA
    Plast Reconstr Surg 125:363-71. 2010
    ..This study defines a correction modality for the adverse results of subpectoral implant placement in augmentation mammaplasty...
  18. ncbi Breast implants: the good, the bad and the ugly. Can nanotechnology improve implants?
    Judit E Puskas
    College of Engineering, College of Polymer Science and Polymer Engineering, Goodyear Polymer Center, The University of Akron, Akron, OH, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 4:153-68. 2012
    ..The most prevalent issues involving breast implants include capsular contracture, gel bleed, implant rupture, and infection...
  19. ncbi Retrospective case review of capsular contracture after two-stage breast reconstruction: is colonization of the tissue expander pocket associated with subsequent implant capsular contracture?
    Sheina A Macadam
    Division of Plastic and Reconstructive Surgery, University of Alberta, Edmonton, Alberta, Canada
    Ann Plast Surg 53:420-4. 2004
    ..0013). These results suggest that colonization of the expander occurs frequently, irradiation predisposes to contracture, and colonization did not contribute to secondary implant contracture in this study population...
  20. ncbi Acellular dermal matrix in aesthetic revisionary breast surgery
    G Patrick Maxwell
    Department of Plastic Surgery, Loma Linda University Medical Center, Loma Linda, California, USA
    Aesthet Surg J 31:65S-76S. 2011
    ....
  21. pmc The association of matrix Gla protein isomers with calcification in capsules surrounding silicone breast implants
    Larry W Hunter
    Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA
    Biomaterials 32:8364-73. 2011
    ..that MGP, in its vitamin K-activated conformer, may represent a pharmacological target to sustain the health of the peri-prosthetic tissue which encapsulates silicone breast implants as well as other implanted silicone medical devices.
  22. ncbi Surface and mechanical analysis of explanted Poly Implant Prosthèse silicone breast implants
    L Yildirimer
    Department of Plastic and Reconstructive Surgery, Royal Free Hospital Hampstead NHS Trust, and University College London Centre for Nanotechnology and Regenerative Medicine, UCL Division of Surgery and Interventional Science, UCL, London, UK
    Br J Surg 100:761-7. 2013
    The recent events surrounding Poly Implant Prosthèse (PIP) breast implants have renewed the debate about the safety profile of silicone implants...
  23. ncbi Late hematogenous bacterial infections of breast implants: two case reports of unique bacterial infections
    Jill Chang
    Changes Plastic Surgery, San Diego, CA, USA
    Ann Plast Surg 67:14-6. 2011
    Late infections of breast implants are rare occurrences. We present 2 cases of late infections of breast implants, resulting from hematogenous spread from bacterial infection from distant sites...
  24. ncbi Degenerative mineralization in the fibrous capsule of silicone breast implants
    André P Legrand
    Laboratoire de Physique Quantique, ESPCI, 10 rue Vauquelin, 75005, Paris, France
    J Mater Sci Mater Med 16:477-85. 2005
    The formation of a fibrous capsule made of long collagen fibers surrounding breast implants represents an unavoidable phenomenon as the patient's reaction to the presence of a foreign body...
  25. ncbi Subclinical infection in breast capsules
    David T Netscher
    Plast Reconstr Surg 114:818-20. 2004
  26. ncbi A systematic review and meta-analysis of complications associated with acellular dermal matrix-assisted breast reconstruction
    Goretti Ho
    Division of Plastic and Reconstructive Surgery, Keck School of Medicine of University of Southern California, Los Angeles, CA 90033, USA
    Ann Plast Surg 68:346-56. 2012
    ..The purpose of this study was to conduct a systematic review and meta-analysis to determine an aggregate estimate of risks associated with ADM-assisted breast reconstruction...
  27. ncbi Public health implications of differences in U.S. and European Union regulatory policies for breast implants
    Diana Zuckerman
    National Research Center for Women and Families, Washington, DC, USA
    Reprod Health Matters 20:102-11. 2012
    The recall of tens of thousands of defective breast implants in Europe in 2011-12 as well as new data on risks have raised questions about regulatory standards for these and other medical implants in the United States (U.S...
  28. ncbi Acellular dermal matrix for the treatment and prevention of implant-associated breast deformities
    Scott L Spear
    Department of Plastic Surgery, Georgetown University Hospital, Washington, DC 20007, USA
    Plast Reconstr Surg 127:1047-58. 2011
    ..This study investigates the use of acellular dermal matrix for correction or prevention of implant-associated breast deformities...
  29. ncbi Still's disease, lupus-like syndrome, and silicone breast implants. A case of 'ASIA' (Shoenfeld's syndrome)
    L J Jara
    Hospital de Especialidades Centro Medico La Raza, IMSS, Mexico City, Mexico
    Lupus 21:140-5. 2012
    ..At the age of 22 she underwent silicone breast implants and presented with a transient lupus-like syndrome...
  30. ncbi Silicone breast implants: correlation between implant ruptures, magnetic resonance spectroscopically estimated silicone presence in the liver, antibody status and clinical symptoms
    M Gaubitz
    Department of Medicine B, University of Munster, Munster, Germany
    Rheumatology (Oxford) 41:129-35; discussion 123-4. 2002
    To determine the impact of implant integrity on clinical symptoms and antibody status in women with silicone breast implants (SBIs).
  31. ncbi Immediate reconstruction with an expander/implant following ablatio mammae because of breast cancer : side effects and cosmetic results after adjuvant chest wall radiotherapy
    Marc D Piroth
    Department of Radiotherapy, University Hospital, RWTH Aachen, Aachen, Germany
    Strahlenther Onkol 185:669-74. 2009
    ..The aim of the present study was to assess the influence of adjuvant radiotherapy on morbidity and patient satisfaction after allogenous breast reconstruction...
  32. pmc Breast implants following mastectomy in women with early-stage breast cancer: prevalence and impact on survival
    Gem M Le
    Northern California Cancer Center, Fremont, California, USA
    Breast Cancer Res 7:R184-93. 2005
    Few studies have examined the effect of breast implants after mastectomy on long-term survival in breast cancer patients, despite growing public health concern over potential long-term adverse health effects.
  33. ncbi Epidemiology of silicone-gel breast implants
    S Lori Brown
    Office of Surveillance and Biometrics, Center for Devices and Radiological Health, Food and Drug Administration, Rockville, MD 20850, USA
    Epidemiology 13:S34-9. 2002
    Silicone breast implants have been marketed in the United States since 1963. Questions remain unanswered on the safety of these medical devices despite their popularity and availability...
  34. ncbi Immunogenetic differences between Caucasian women with and those without silicone implants in whom myositis develops
    Terrance O'Hanlon
    Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, NIH, 9 Memorial Drive, Bethesda, MD 10892, USA
    Arthritis Rheum 50:3646-50. 2004
    To determine whether patients in whom myositis develops after they receive silicone breast implants have distinct clinical, serologic, and/or immunogenetic features compared with patients with myositis who do not have silicone implants.
  35. ncbi Silicone breast implants and connective tissue disease: no association
    Loren Lipworth
    International Epidemiology Institute, 1455 Research Blvd, Suite 550, Rockville, MD 20850, USA
    Semin Immunopathol 33:287-94. 2011
    The association of silicone breast implants with connective tissue diseases (CTDs), including systemic sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and fibromyalgia, as well as a hypothesized new "atypical" disease, ..
  36. pmc Immediate breast reconstruction-impact on radiation management
    Ravi A Shankar
    Department of Radiation Oncology, Howard University Hospital, Washington DC 20060, USA
    J Natl Med Assoc 95:286-95. 2003
    ..reconstruction is performed by insertion of a temporary tissue expander prior to the placement of permanent breast implants. Some of these patients, following mastectomy, may require chest wall irradiation to prevent loco regional ..
  37. ncbi Breast implants as a possible etiology of epithelioid hemangioendothelioma and successful therapy with interferon-alpha2
    Robert de Wilton Marsh
    University of Florida College of Medicine, Gainesville, Florida
    Breast J 11:257-61. 2005
    ..This review proposes polyurethane/silicone breast implants as a potential cause of the condition and highlights the dramatic response to interferon (IFN)-alpha in a ..
  38. pmc Prospective cohort study of breast implants and the risk of connective-tissue diseases
    I Min Lee
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Int J Epidemiol 40:230-8. 2011
    A 2000 meta-analysis indicated no overall association between breast implants and risk of connective-tissue diseases (CTDs)...
  39. ncbi Staged breast reconstruction with saline-filled implants in the irradiated breast: recent trends and therapeutic implications
    S L Spear
    Georgetown University Medical Center, Washington, DC 20007, USA
    Plast Reconstr Surg 105:930-42. 2000
    ..Purely autologous reconstruction such as a TRAM flap is another option for these patients, either before or after radiation therapy...
  40. ncbi Immediate bilateral breast reconstruction with implants and inferolateral AlloDerm slings
    Karl H Breuing
    Division of Plastic Surgery, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Ann Plast Surg 55:232-9. 2005
    ..We have selectively used this technique as a reconstructive option for 10 women undergoing bilateral mastectomy (20 breasts)...
  41. ncbi Breast lymphoma associated with breast implants: two case-reports and a review of the literature
    Guylaine Gaudet
    Department of Adult Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Leuk Lymphoma 43:115-9. 2002
    ..Even fewer cases of breast lymphomas have been reported in women who have received breast implants. Silicone, a frequent component of breast implants, has been extensively investigated as a possible etiologic ..
  42. ncbi Evaluation of the rupture of silicone breast implants by mammography, ultrasonography and magnetic resonance imaging in asymptomatic patients: correlation with surgical findings
    Anabel Medeiros Scaranelo
    Department of Diagnostic Imaging, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Sao Paulo Med J 122:41-7. 2004
    Different imaging methods can identify the integrity of breast implants and also the extent of possible silicone leakage...
  43. ncbi Evaluation of HDR interstitial breast implants planned by conventional and optimized CT-based dosimetry systems with respect to dose homogeneity and conformality
    Tibor Major
    Radiotherapy Department, National Institute of Oncology, 7 9 Rath Gy u, 1122 Budapest, Hungary
    Strahlenther Onkol 181:89-96. 2005
    ..The aim of this study was to make dosimetric comparisons between conventional (CONV) and CT-based optimized dosimetry systems applied to breast implants.
  44. ncbi An outbreak of Mycobacterium jacuzzii infection following insertion of breast implants
    G Rahav
    Sheba Medical Center, Tel Hashomer, Israel
    Clin Infect Dis 43:823-30. 2006
    Surgical wound infections caused by rapidly growing mycobacteria developed in 15 women after insertion of breast implants from August to November 2003 at a single medical center.
  45. ncbi Seroma-associated primary anaplastic large-cell lymphoma adjacent to breast implants: an indolent T-cell lymphoproliferative disorder
    Anja C Roden
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Mod Pathol 21:455-63. 2008
    ..four patients with primary T-cell anaplastic large-cell lymphoma presenting adjacent to silicone or saline breast implants. All patients presented with seroma and neoplastic cells were identified in suspension in the serous fluid ..
  46. ncbi Immediate breast reconstruction in two stages using textured, integrated-valve tissue expanders and breast implants
    Scott L Spear
    Division of Plastic Surgery, Georgetown University Hospital, Washington, DC 20007, USA
    Plast Reconstr Surg 113:2098-103. 2004
  47. pmc Risk of connective tissue disease and related disorders among women with breast implants: a nation-wide retrospective cohort study in Sweden
    O Nyren
    Department of Medical Epidemiology, Karolinska Institute, Stockholm, Sweden
    BMJ 316:417-22. 1998
    To examine the relation between connective tissue disease and related conditions and breast implants.
  48. ncbi Ki67, HSP70 and TUNEL for the specification of testing of silicone breast implants in vivo
    Wulf Siggelkow
    Department of Obstetrics and Gynecology, Aachen
    J Mater Sci Mater Med 15:1355-60. 2004
    This investigation of capsular tissue adjacent to silicone breast implants concerns the long-term tissue response to the implant environment. Fifty-three silicone breast implants have been analyzed at the time of explantation...
  49. ncbi Silicone breast implants and connective tissue disease: an updated review of the epidemiologic evidence
    Loren Lipworth
    International Epidemiology Institute, Rockville, MD 20850, USA
    Ann Plast Surg 52:598-601. 2004
    ..through 1999, which have been conducted to evaluate the potential association between cosmetic silicone breast implants and the occurrence of well-defined connective tissue diseases, as well as a hypothesized new atypical disease,..
  50. ncbi The Mentor Core Study on Silicone MemoryGel Breast Implants
    Bruce Cunningham
    Department of Plastic and Reconstructive Surgery, University of Minnesota, USA
    Plast Reconstr Surg 120:19S-29S; discussion 30S-32S. 2007
    ..In 2005, convincing safety and efficacy data were presented, resulting in the approval of Mentor MemoryGel Implants, with conditions...
  51. ncbi The owl technique combined with the inferior pedicle in mastopexy
    Hugo D Loustau
    Plastic Surgery Department, Hospital Italiano de Buenos Aires, University of Buenos Aires, School of Medicine, Gascon, 450, Buenos Aires, Argentina
    Aesthetic Plast Surg 32:11-5; discussion 16-7. 2008
    ..The authors aim to show the results from combining the owl technique with the inferior pedicle for the treatment of patients who have mammary ptosis with or without hypertrophy...
  52. ncbi Inamed silicone breast implant core study results at 6 years
    Scott L Spear
    Department of Plastic Surgery, Georgetown University Hospital, Washington, DC 20007 2113, USA
    Plast Reconstr Surg 120:8S-16S; discussion 17S-18S. 2007
    Silicone gel-filled breast implants were developed in 1962 but did not fall under the auspices of the U.S. Food and Drug Administration until 1976 and were not classified as class III devices until 1988...
  53. ncbi Style 410 highly cohesive silicone breast implant core study results at 3 years
    Bradley P Bengtson
    Plastic Surgery Associates and Medical Education Research Center, Grand Rapids, Mich 49503, USA
    Plast Reconstr Surg 120:40S-48S. 2007
    ..In February of 2001, Allergan (formerly Inamed) began an Investigational Device Exemption study of a shaped breast implant: the Style 410 highly cohesive silicone-filled breast implant...
  54. ncbi Textured surface breast implants in the prevention of capsular contracture among breast augmentation patients: a meta-analysis of randomized controlled trials
    G Philip Barnsley
    Department of Surgery, Division of Plastic Surgery, Dalhousie University
    Plast Reconstr Surg 117:2182-90. 2006
    Capsular contracture is a common complication associated with the use of breast implants. Numerous randomized controlled trials addressing the efficacy of textured surface breast implants in reducing capsular contracture have yielded ..
  55. ncbi Local complications after cosmetic breast implant surgery in Finland
    Ilona Kulmala
    Tampere School of Public Health, Tampere University, Finland
    Ann Plast Surg 53:413-9. 2004
    Concerns regarding potential health effects of silicone breast implants have recently shifted from long-term illnesses to postoperative local complications...
  56. pmc Interference of breast implants with echocardiographic image acquisition and interpretation
    Mohammad Reza Movahed
    University of Arizona Sarver Heart Center, Department of Medicine, Section of Cardiology, Tucson, Arizona, USA
    Cardiovasc Ultrasound 5:9. 2007
    ..b>Breast implants are increasing in popularity in the USA and the Federal Drug and Food Administration (FDA) just approved ..
  57. ncbi Pathology of lymph nodes from patients with breast implants: a histologic and spectroscopic evaluation
    William E Katzin
    Departments of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Am J Surg Pathol 29:506-11. 2005
    ..are only a few published reports describing the pathology of regional lymph nodes from patients with silicone breast implants. Systematic analytical chemical verification of foreign material has not previously been reported...
  58. ncbi Augmentation mammaplasty with anatomic soft, cohesive silicone implant using the transaxillary approach at a subfascial level with endoscopic assistance
    JoseMaría Serra-Renom
    Department of Plastic and Reconstructive Surgery, University Clinic Hospital, University of Barcelona Medical School, Aesthetic Surgery Institute Dr Serra Renom, Barcelona, Spain
    Plast Reconstr Surg 116:640-5. 2005
    ..Many augmentation mammaplasty techniques have been developed paying special attention to incision location and pocket plane to achieve more natural-looking breasts...
  59. ncbi [Round and anatomical mammary implants. Respective advantages and disadvantages]
    E Auclair
    IECEP, 10, rue Anna Jacquin, 92100 Boulogne, France
    Ann Chir Plast Esthet 50:505-16. 2005
    ..He shows a strategie of mammary augmentation that favorise the premuscular position and define the respective place of round and anatomical implants...
  60. ncbi Style 410 cohesive silicone breast implants: safety and effectiveness at 5 to 9 years after implantation
    Per Hedén
    Department of Plastic Surgery, Akademikliniken Hospital, Stockholm, Sweden
    Plast Reconstr Surg 118:1281-7. 2006
    ..To date, little has been published on this implant despite its widespread use in Europe, and no data are available on its long-term rupture rate...
  61. ncbi Early experience with an anatomical soft cohesive silicone gel prosthesis in cosmetic and reconstructive breast implant surgery
    Birgit H Fruhstorfer
    Department of Plastic and Reconstructive Surgery and Cambridge Breast Unit, Addenbrooke s Hospital, Cambridge, UK
    Ann Plast Surg 53:536-42. 2004
    ..Anatomic soft cohesive gel implants provide excellent results in selected cases. They are well accepted by patients and not associated with an increased rate of complications...
  62. ncbi Cancer risk among Los Angeles women with cosmetic breast implants
    Dennis M Deapen
    Department of Preventive Medicine, Division of Plastic Surgery, and Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Plast Reconstr Surg 119:1987-92. 2007
    As the first generation of women who received cosmetic breast implants ages, questions remain about cancer risk...
  63. ncbi Breast cancer following augmentation mammoplasty - a review of its impact on prognosis and management
    S A McIntosh
    Department of Surgery, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK
    J Plast Reconstr Aesthet Surg 60:1127-35. 2007
    ..This article reviews the literature on the prognosis of breast cancer patients with a history of augmentation mammoplasty and examines the available data regarding their surgical treatment...
  64. ncbi Prospective study comparing two brands of cohesive gel breast implants with anatomic shape: 5-year follow-up evaluation
    Igor Niechajev
    Lidingö Clinic, Torsvägen 30, S 181 32 Lidingö, Sweden
    Aesthetic Plast Surg 31:697-710. 2007
    The new generation of breast implants has an anatomic shape. These implants are made with a textured shell and filled with a cohesive silicone gel...
  65. ncbi Inflammatory F-18 FDG uptake secondary to ruptured breast prosthesis
    Peeyush Bhargava
    Division of Nuclear Medicine, St Luke s Roosevelt Hospital Center, New York, NY 07073, USA
    Clin Nucl Med 31:227-8. 2006
    ..The patient underwent surgery for the replacement of the prosthesis, which did not show any evidence of neoplastic disease...
  66. ncbi Platinum in silicone breast implants
    Michael A Brook
    Department of Chemistry, McMaster University, 1280 Main Street W, Hamilton, Ont, Canada L8S 4M1
    Biomaterials 27:3274-86. 2006
    Silicone elastomers are widely used in implantable devices, including silicone breast implants. These rubbers are generally formed/cured using platinum-catalyzed hydrosilylation...
  67. ncbi The diagnosis of silicone breast-implant rupture: clinical findings compared with findings at magnetic resonance imaging
    Lisbet Rosenkrantz Hölmich
    Danish Cancer Society, Institute of Cancer Epidemiology, Copenhagen, Denmark
    Ann Plast Surg 54:583-9. 2005
    ..In this study, we found that when a clinical examination is used as the sole diagnostic tool to identify implant rupture, neither the sensitivity nor the specificity is acceptable...
  68. ncbi Silicone filled breast implants and the risk of fibromyalgia and rheumatoid arthritis
    F Wolfe
    Arthritis Research Center and University of Kansas School of Medicine, Wichita, KS 67214, USA
    J Rheumatol 26:2025-8. 1999
    ..It has been hypothesized that silicone (filled) breast implants (SBI) might be causally related to the development of FM...
  69. ncbi Multicenter study to assess potential hazards from exposure to lipid peroxidation products in soya bean oil from Trilucent breast implants
    G M Williams
    Department of Pathology, New York Medical College, Valhalla, NY 10595, USA
    Regul Toxicol Pharmacol 53:107-20. 2009
    ....
  70. ncbi Lumpy silicone-injected breasts: enhanced MRI and microscopic correlation
    Yun Chung Cheung
    Department of Diagnostic Radiology, Chang Gung Memorial Hospital, 5 Fu Hsing Street, Kwei Shan, Tao Yuan Hsien, Taiwan
    Clin Imaging 26:397-404. 2002
    ..On the other hand, these illustrations indicated the importance of enhancement technique in detecting the cancers and in differentiating the angiogenic lesions from nonenhanced silicone granulomas...
  71. ncbi Breast augmentation and reconstructive surgery: MR imaging of implant rupture and malignancy
    Christoph U Herborn
    Institute of Diagnostic Radiology, University Hospital, Zurich, Switzerland
    Eur Radiol 12:2198-206. 2002
    ..Magnetic resonance imaging is a reliable and reproducible technique for diagnosing both implant rupture and malignant lesions in women after breast augmentation and reconstruction...
  72. ncbi Women's psychosocial outcomes of breast augmentation with silicone gel-filled implants: a 2-year prospective study
    Thomas F Cash
    Department of Psychology, Old Dominion University, Norfolk, VA 23529 0267, USA
    Plast Reconstr Surg 109:2112-21; discussion 2122-3. 2002
    ..surrounding the Food and Drug Administration's voluntary moratorium on the use of silicone gel-filled breast implants, which occurred during the study, revealed a limited effect, if any, on women's psychosocial outcomes...
  73. ncbi Safety and effectiveness of Mentor's MemoryGel implants at 6 years
    Bruce Cunningham
    Division of Plastic and Reconstructive Surgery, University of Minnesota Medical School, Mayo Memorial Bldg, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Aesthetic Plast Surg 33:440-4. 2009
    ..2006, the FDA approved the Premarket Approval PMA applications for the round, cohesive, silicone gel-filled breast implants of Mentor (MemoryGel) and Allergan...
  74. ncbi Comparison of the capsular response to the Biocell RTV and Mentor 1600 Siltex breast implant surface texturing: a scanning electron microscopic study
    A M Danino
    Department of Plastic and Reconstructive Surgery, Saint Louis University Hospital of Paris, France
    Plast Reconstr Surg 108:2047-52. 2001
    ..If this last is not directly linked to the prevention of capsular contracture, it can have an effect on implant stabilization in the primary mammary reconstruction and in the secondary corrections of asymmetry or bad position...
  75. ncbi Do silicone breast implants cause rheumatologic disorders? A systematic review for a court-appointed national science panel
    P Tugwell
    Centre for Global Health, University of Ottawa, Institute of Population Health, Ontario, Canada
    Arthritis Rheum 44:2477-84. 2001
    ..Panel to assess whether existing studies provide scientific evidence of an association between silicone breast implants and systemic classic/accepted connective disease, atypical connective disease, and certain signs and symptoms ..
  76. ncbi Infections related to breast implants reported to the Food and Drug Administration, 1977-1997
    S L Brown
    Office of Surveillance and Biometrics, Center for Devices and Radiological Health, Food and Drug Administration, Rockville, MD 20850, USA
    J Long Term Eff Med Implants 11:1-12. 2001
    ..There was a large increase in the number of reports on infections related to breast implants between 1992 and 1995 due to the publicity and litigation surrounding breast implants...
  77. ncbi Complications in breast augmentation: prevention and correction
    M A Codner
    Paces Plastic Surgery, Atlanta, Georgia, USA
    Clin Plast Surg 28:587-95; discussion 596. 2001
    ..Patients should understand clearly the immediate and long-term risks associated with breast augmentation and the requirement for future reoperation...
  78. ncbi Breast augmentation with full-height anatomic saline implants: the pros and cons
    J B Tebbetts
    Clin Plast Surg 28:567-77. 2001
    ..Absent the willingness and skills development to meet these requirements, surgeons should avoid using anatomic implants...
  79. ncbi Patient evaluation, operative planning, and surgical techniques to increase control and reduce morbidity and reoperations in breast augmentation
    J B Tebbetts
    Clin Plast Surg 28:501-21. 2001
    ....
  80. ncbi Monocyte-dependent stimulation of human T cells by silicon dioxide
    D L Smalley
    Baptist Regional Laboratories, The University of Tennessee, Memphis, Tenn, USA
    Pathobiology 66:302-5. 1998
    ..These results confirm the T-cell response to silicon dioxide is monocyte-dependent and not a superantigen as has been speculated...
  81. ncbi Monoclonal gammopathy of undetermined significance and exposure to breast implants
    E W Karlson
    Harvard Medical School, Boston, MA 02115
    Arch Intern Med 161:864-7. 2001
    ..Animal studies and uncontrolled case series in humans have suggested a possible association between breast implant exposure and monoclonal gammopathy...
  82. ncbi Textured-surface saline-filled silicone breast implants for augmentation mammaplasty
    S L Spear
    Division of Plastic Surgery, Georgetown University Medical Center, Washington, DC 20007, USA
    Plast Reconstr Surg 105:1542-52; discussion 1553-4. 2000
    The earliest silicone breast implants were smooth-surface, silicone rubber devices filled with either silicone gel or saline...
  83. ncbi Meta-analyses of the relation between silicone breast implants and the risk of connective-tissue diseases
    E C Janowsky
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, 27599, USA
    N Engl J Med 342:781-90. 2000
    The postulated relation between silicone breast implants and the risk of connective-tissue and autoimmune diseases has generated intense medical and legal interest during the past decade...
  84. ncbi Analysis of risk factors associated with rupture of silicone gel breast implants
    L J Feng
    Mount Sinai Medical Center, Department of Epidemiology and Biostatistics, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
    Plast Reconstr Surg 104:955-63. 1999
    ..The knowledge will enable the medical community to better advise their breast implant population regarding durability and appropriate time for removal or replacement...
  85. ncbi Anaplastic large-cell lymphoma in women with breast implants
    Daphne de Jong
    Department of Pathology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066CX, The Netherlands
    JAMA 300:2030-5. 2008
    ..Similar cases have been reported in the literature. Although an increased risk of ALCL in patients with breast prostheses has been speculated, no studies have been conducted so far...
  86. ncbi Subfascial breast implant: a new procedure
    Ruth Maria Graf
    Plastic Surgery Department, Federal University of Parana, Curitiba, Brazil
    Plast Reconstr Surg 111:904-8. 2003
    ..These technical details lead to fewer patient complaints. Morbidity is similar to that of other techniques...
  87. ncbi Women's health after plastic surgery
    H Englert
    Westmead Hospital, Sydney, New South Wales, Australia
    Intern Med J 31:77-89. 2001
    BACKGROUND: Allegations that exposure to endogenous silicone, especially related to breast implants, might be causally related to connective tissue disease originated from case studies...
  88. ncbi Cohesive silicone gel breast implants in aesthetic and reconstructive breast surgery
    Mitchell H Brown
    Division of Plastic Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Plast Reconstr Surg 116:768-79; discussion 780-1. 2005
    Cohesive silicone gel breast implants are composed of a textured silicone elastomer shell and are filled with cohesive silicone gel...
  89. ncbi F-18 FDG positron emission tomographic imaging in a case of ruptured breast implant: inflammation or recurrent tumor?
    Robert Hurwitz
    Department of Radiology and Nuclear Medicine, Hoag Memorial Hospital Presbyterian, Newport Beach, California 92658 6100, USA
    Clin Nucl Med 28:755-6. 2003
    ..An F-18 FDG PET scan demonstrated intense uptake in these nodes. Lymph node biopsy demonstrated benign inflammatory reaction and no recurrence of malignancy...
  90. ncbi Effect of breast augmentation on the accuracy of mammography and cancer characteristics
    Diana L Miglioretti
    Center for Health Studies, Group Health Cooperative, Department of Biostatistics, University of Washington, Seattle, Wash 98101, USA
    JAMA 291:442-50. 2004
    ..Breast augmentation is not associated with an increased risk of breast cancer; however, implants may interfere with the detection of breast cancer thereby delaying cancer diagnosis in women with augmentation...
  91. ncbi Silicone breast implants may be close to US approval
    Alicia Ault
    Lancet 362:1384. 2003
  92. ncbi Immediate breast reconstruction with saline-filled implants: no interference with the oncologic outcome?
    E Vandeweyer
    Plastic and Reconstructive Surgery, Department and the Breast Diseases Surgery Department at Jules Bordet Institute for Cancer, Brussels, Belgium
    Plast Reconstr Surg 107:1409-12. 2001
    ..immediate breast reconstruction with saline-filled implants, 49 patients reconstructed with saline-filled breast implants at the Jules Bordet Cancer Institute were studied...
  93. ncbi Long-term health status of Danish women with silicone breast implants
    Vibeke B Breiting
    Holte Clinic of Plastic Surgery, Denmark
    Plast Reconstr Surg 114:217-26; discussion 227-8. 2004
    Long-term safety data are important in the evaluation of possible adverse health outcomes related to silicone breast implants. The authors evaluated long-term symptoms and conditions and medication use among 190 Danish women with ..
  94. ncbi Matrix metalloproteinases, tissue inhibitors of metalloproteinases, aminoterminal propeptide of procollagen type III, and hyaluronan in sera and tissue of patients with capsular contracture after augmentation with Trilucent breast implants
    Dietmar Ulrich
    Department of Plastic Surgery and Hand Surgery, University Hospital, Aachen University of Technology, Aachen, Germany
    Plast Reconstr Surg 114:229-36. 2004
    ..In the histologic evaluation, there was a chronic inflammatory reaction in the capsules around the breast implants and refracting material within the substance...
  95. ncbi MR imaging of extracapsular silicone from breast implants: diagnostic pitfalls
    Wendie A Berg
    Department of Radiology, University of Maryland, University Imaging Center, 419 W Redwood St, Ste 110, Baltimore, MD 21201, USA
    AJR Am J Roentgenol 178:465-72. 2002
    ..We sought to identify pitfalls in recognition of extracapsular silicone on MR imaging...
  96. ncbi Reduction of capsular thickness around silicone breast implants by zafirlukast in rats
    A Spano
    Plastic Surgery Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
    Eur Surg Res 41:8-14. 2008
    ..Our study confirms the effectiveness of this compound in preventing fibrosis and putatively also in reducing the extent of collagen reaction when a capsule has been formed...
  97. ncbi Mortality among augmentation mammoplasty patients
    L A Brinton
    Environmental Epidemiology Branch, National Cancer Institute, 6120 Executive Boulevard, Room 7068, Bethesda, MD 20892-7234, USA
    Epidemiology 12:321-6. 2001
    Much attention has focused on disease risks among women receiving silicone breast implants, but there has been little evaluation of their mortality experience...
  98. ncbi Capsular contracture in subglandular breast augmentation with textured versus smooth breast implants: a systematic review
    Chin Ho Wong
    Department of Plastic Surgery, Singapore General Hospital, Singapore
    Plast Reconstr Surg 118:1224-36. 2006
    ..The authors reviewed the literature to evaluate the effectiveness of surface texturization in reducing capsular contracture...
  99. ncbi Retromammary fluid collection as a late complication of breast implants: magnetic resonance imaging findings
    Victor Pineda
    Department of Radiology, H G Vall d Hebron, Universitat Autonoma de Barcelona, Spain
    J Comput Assist Tomogr 28:386-9. 2004
    ..It is important for radiologists to know the MRI findings of this complication, which suggest the correct diagnosis, avoiding unnecessary additional procedures...
  100. ncbi Use of the rectus sternalis in augmentation mammoplasty: case report and literature search
    Umar Daraz Khan
    Belvedere Private Hospital, Knee Hill Abbeywood, London, SE2 0GD, UK
    Aesthetic Plast Surg 32:21-4. 2008
    ..The rectus sternalis, an nomalous muscle, may interfere with the submuscular pocket dissection when an intraalveolar or submammary approach is used. The use of this muscle to cover the prosthesis in its most medial part is presented...
  101. ncbi MOC-PSSM CME article: Breast reconstruction
    Leif Sigurdson
    Division of Plastic Surgery, Dalhousie University, Halifax, Nova Scotia B3H 3A7, Canada
    Plast Reconstr Surg 121:1-12. 2008
    ..3. Gain knowledge about the indications and contraindications for different breast reconstructive procedures. 4. Understand the complications inherent to different reconstructive breast procedures...

Research Grants32

  1. Stem Cell Based Soft Tissue Reconstruction
    Jeremy J Mao; Fiscal Year: 2010
    ..and with severe clinical consequences as exemplified by the reported negative sequela of silicone breast implants. The surgical literature is replete with continuing aspiration to 'grow'patient's own soft ..
  2. Novel Translucent Nanocomposite Biomaterials
    Judit E Puskas; Fiscal Year: 2010
    ..The existing design and material choice of silicone rubber for breast implants are associated with health complications, such as gel bleed and capsular contracture, to require patients to ..
  3. COX-2 Mediated Vascular Toxicity of Methylenedianiline
    TAMMY DUGAS; Fiscal Year: 2003
    ..polyurethanes, which are made into a plethora of products ranging from floor coverings to dialysis tubing and breast implants. This new discovery raises the possibility that other aromatic amines, ubiquitous compounds found in a ..
  4. PET Imaging of Breast Cancer via Sigma-2 Receptors
    Robert Mach; Fiscal Year: 2006
    ..e., women with dense breast tissue, breast implants, or scar tissue for an earlier biopsy study) that interfere with the identification of abnormalities that may ..
  5. PET Imaging of Breast Cancer via Sigma-2 Receptors
    Robert Mach; Fiscal Year: 2003
    ..e., women with dense breast tissue, breast implants, or scar tissue for an earlier biopsy study) that interfere with the identification of abnormalities that may ..
  6. IMMOBILIZATION OF ANTIMICROBIAL PEPTIDES
    LISE DURAN; Fiscal Year: 1992
    ..Infection of catheters, orthopedic and dental prostheses, vascular grafts and valves, pacemaker leads, breast implants, and cerebrospinal fluid shunts can lead to re-operation, amputation, or death...
  7. Microarray Analysis of Wounds
    AMY COLWELL; Fiscal Year: 2004
    ..We hypothesize these genes can be used to modulate the biology of adult wound healing. This first step will form our basis for developing treatment to induce scarless healing. ..
  8. Obesity, Body Image and Weight Maintenance
    DAVID SARWER; Fiscal Year: 2005
    ..These studies have been selected to further develop my knowledge of the treatment of obesity, and the training program has been designed to facilitate my development as an independent investigator in the field of obesity. ..
  9. 3D Adipose Tissue Generation and Functional Verification
    Charles Patrick; Fiscal Year: 2004
    ..abstract_text> ..
  10. Changes in sexual function following bariatric surgery
    DAVID SARWER; Fiscal Year: 2009
    ..The proposed study is innovative, as it will provide new and important information on the long-term effects of bariatric surgery on these important areas of quality of life. ..
  11. BREAST CANCER STAGING WITH MRI PRIOR RE-EXCISION
    Susan Orel; Fiscal Year: 2001
    ..Correlation of MRI, mammographic, clinical, and pathological findings will generate a profile of patients at risk for occult, diffuse or multifocal disease who should undergo MRI prior to treatment recommendation. ..
  12. VASCULARIZATION IN TISSUE ENGINEERED CONSTRUCTS
    Charles Patrick; Fiscal Year: 2001
    ..does TEC-recipient inosculation play in TEC vascularization? (b) What are the biological functions of CD144, principally with regards to its role in inosculation and its regulation by the unique TEC microenvironment? ..
  13. Postoperative dietary counseling after bariatric surgery
    DAVID SARWER; Fiscal Year: 2005
    ..Results of this study could have a significant impact on the postoperative care of these individuals. ..
  14. HEROIN AIDS ENCEPHALOPATHY--NEUROPATHOGENESIS MECHANISMS
    Madhavan Nair; Fiscal Year: 2005
    ..Further studies will elucidate the molecular mechanisms underlying the immuno- and neuropathogenic effects of heroin use in HIV-l infection, and may yield novel therapies for the treatment of heroin using, HIV-infected patients. ..
  15. AIDS encephalopathy and HIV disease: role of opioids
    Madhavan Nair; Fiscal Year: 2006
    ..abstract_text> ..
  16. World Workshop in Oral Medicine IV
    Peter Lockhart; Fiscal Year: 2005
    ..The proceedings will be published as evidence-based recommendations for best clinical practice in Oral Medicine as well as providing suggestions for future basic science and clinical research. ..
  17. New Technology for Computed Radiography
    Andrew Karellas; Fiscal Year: 2008
    ..The potential impact of this inherently low-cost high resolution CR plate reader in a cassette-like package can be very high as it can be easily adapted to the needs of current clinical practice. ..
  18. Communication Between Patients and their Providers
    PATRICIA PARKER; Fiscal Year: 2005
    ....
  19. Immunopathogenesis of HIV-1 Infection: Role of Methamphetamine
    Madhavan P Nair; Fiscal Year: 2010
    ....
  20. DIGITAL MAMMOGRAPHY HIGH RESOLUTION FLAT PANEL IMAGER
    Andrew Karellas; Fiscal Year: 2002
    ..The proposed prototype using an array of seamlessly tiled CCDs coupled to a structured CsI:TI scintillator by a non-tapering fiberoptic plate will deliver the highest resolution than any other flat panel mammographic detector. ..
  21. Archiving the Charleston Heart Study
    Paul Nietert; Fiscal Year: 2002
    ..abstract_text> ..
  22. Bacteremia from Dental Extraction vs. Oral Hygiene
    Peter Lockhart; Fiscal Year: 2004
    ..Additionally, we will have unique and critical data for the development of both future research and evidence-based guidelines concerning antibiotic prophylaxis for individuals currently felt to be at risk for DSI. ..
  23. Cocaine/Immuno and Neuropathogenesis of HIV-1 Infection
    Madhavan Nair; Fiscal Year: 2008
    ..These studies may lead to novel anti-HIV therapies such as targeting the CD4 independent, virus attachment receptor, DC-SIGN, or devising inhibitors of TDO and DC-SIGN or stimulating costimulatory molecules. ..
  24. ANTIOXIDANTS AND FEMALE HORMONES IN THE ETIOLOGY OF RA
    Elizabeth Karlson; Fiscal Year: 2002
    ..RA will be confirmed by a screening questionnaire regarding rheumatic symptoms and review of medical records. The study will identify potentially modifiable risk factors for primary prevention of RA. ..
  25. Dermatopharmacokinetics: In Vivo Analysis of Solvents
    Karla Thrall; Fiscal Year: 2005
    ..To evaluate the kinetics and dermal bioavailability of ethylbenzene, styrene, and toluene vapor using F344 rats. ..
  26. Influence of Uncertainty and Communication on Adjustment
    PATRICIA PARKER; Fiscal Year: 2007
    ..The proposed K07 Research Award would allow Dr. Parker to transition into an independent researcher in cancer prevention with a focus on psycho-oncology and physician-patient communication. ..
  27. Colon and liver anticarcinogenicity by acetaminophen
    Gary Williams; Fiscal Year: 2004
    ..In addition, these experiments will provide support for the epidemiological observations of reduced cancer risk associated with the use of APAP. ..
  28. Incidence & Outcomes of SSI After Breast Cancer Surgery
    Margaret Olsen; Fiscal Year: 2008
    ....