indwelling catheters

Summary

Summary: Catheters designed to be left within an organ or passage for an extended period of time.

Top Publications

  1. ncbi An intervention to decrease catheter-related bloodstream infections in the ICU
    Peter Pronovost
    School of Medicine, Johns Hopkins University, Baltimore, USA
    N Engl J Med 355:2725-32. 2006
  2. pmc Vascular access use and outcomes: an international perspective from the Dialysis Outcomes and Practice Patterns Study
    Jean Ethier
    Department of Nephrology, Centre Hospitalier de l Université de Montéal, Montreal, Quebec, Canada
    Nephrol Dial Transplant 23:3219-26. 2008
  3. ncbi Are physicians aware of which of their patients have indwelling urinary catheters?
    S Saint
    Department of Internal Medicine SS, MLB, UDP, SJB, TPH, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Am J Med 109:476-80. 2000
  4. ncbi In vitro evaluation of the risk of developing bacterial resistance to antiseptics and antibiotics used in medical devices
    S M Tambe
    Department of Surgery, College of Physicians and Surgeons of Columbia University, 630 West 168th Street, BB 1734, New York, NY 10032, USA
    J Antimicrob Chemother 47:589-98. 2001
  5. ncbi EBPG on Vascular Access
    Jan Tordoir
    Department of Surgery, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
    Nephrol Dial Transplant 22:ii88-117. 2007
  6. ncbi Determinants of type and timing of initial permanent hemodialysis vascular access
    C O Stehman-Breen
    Department of Surgery, Veterans Administration Puget Sound Health Care System, Seattle, WA 98108, USA
    Kidney Int 57:639-45. 2000
  7. ncbi The preventable proportion of nosocomial infections: an overview of published reports
    S Harbarth
    Infection Control Programme, Department of Internal Medicine, University of Geneva Hospitals, 24, Rue Micheli du Crest, CH 1211, Geneva 14, Switzerland
    J Hosp Infect 54:258-66; quiz 321. 2003
  8. ncbi Laparoscopic omental fixation technique versus open surgical placement of peritoneal dialysis catheters
    G Ogunc
    Department of General Surgery, Akdeniz University Medical School, Dumlupinar Bulvari, 07070, Antalya, Turkey
    Surg Endosc 17:1749-55. 2003
  9. ncbi Guidelines for the prevention of intravascular catheter-related infections
    NAOMI P O'GRADY
    Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
    Infect Control Hosp Epidemiol 23:759-69. 2002
  10. ncbi Sodium citrate versus heparin catheter locks for cuffed central venous catheters: a single-center randomized controlled trial
    Albert Power
    Haemodialysis Research Group, Imperial College Kidney and Transplant Institute, West London Renal and Transplant Centre, Hammersmith Hospital, London, UK
    Am J Kidney Dis 53:1034-41. 2009

Detail Information

Publications278 found, 100 shown here

  1. ncbi An intervention to decrease catheter-related bloodstream infections in the ICU
    Peter Pronovost
    School of Medicine, Johns Hopkins University, Baltimore, USA
    N Engl J Med 355:2725-32. 2006
    ..Catheter-related bloodstream infections occurring in the intensive care unit (ICU) are common, costly, and potentially lethal...
  2. pmc Vascular access use and outcomes: an international perspective from the Dialysis Outcomes and Practice Patterns Study
    Jean Ethier
    Department of Nephrology, Centre Hospitalier de l Université de Montéal, Montreal, Quebec, Canada
    Nephrol Dial Transplant 23:3219-26. 2008
    ..DOPPS is a prospective, observational study of haemodialysis (HD) practices and patient outcomes at >300 HD units from 12 countries and has collected data thus far from >35,000 randomly selected patients...
  3. ncbi Are physicians aware of which of their patients have indwelling urinary catheters?
    S Saint
    Department of Internal Medicine SS, MLB, UDP, SJB, TPH, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Am J Med 109:476-80. 2000
    ....
  4. ncbi In vitro evaluation of the risk of developing bacterial resistance to antiseptics and antibiotics used in medical devices
    S M Tambe
    Department of Surgery, College of Physicians and Surgeons of Columbia University, 630 West 168th Street, BB 1734, New York, NY 10032, USA
    J Antimicrob Chemother 47:589-98. 2001
    ..Although this study indicates that antibiotic catheters may be at a higher risk of being colonized by antibiotic-resistant bacteria, the implications of these results in clinical settings need to be determined...
  5. ncbi EBPG on Vascular Access
    Jan Tordoir
    Department of Surgery, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
    Nephrol Dial Transplant 22:ii88-117. 2007
  6. ncbi Determinants of type and timing of initial permanent hemodialysis vascular access
    C O Stehman-Breen
    Department of Surgery, Veterans Administration Puget Sound Health Care System, Seattle, WA 98108, USA
    Kidney Int 57:639-45. 2000
    ..We undertook a population-based study of hemodialysis (HD) patients to determine which factors are important in predicting the type of permanent access initially placed and if a functional permanent access is in place at the start of HD...
  7. ncbi The preventable proportion of nosocomial infections: an overview of published reports
    S Harbarth
    Infection Control Programme, Department of Internal Medicine, University of Geneva Hospitals, 24, Rue Micheli du Crest, CH 1211, Geneva 14, Switzerland
    J Hosp Infect 54:258-66; quiz 321. 2003
    ....
  8. ncbi Laparoscopic omental fixation technique versus open surgical placement of peritoneal dialysis catheters
    G Ogunc
    Department of General Surgery, Akdeniz University Medical School, Dumlupinar Bulvari, 07070, Antalya, Turkey
    Surg Endosc 17:1749-55. 2003
    ....
  9. ncbi Guidelines for the prevention of intravascular catheter-related infections
    NAOMI P O'GRADY
    Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
    Infect Control Hosp Epidemiol 23:759-69. 2002
    ..Although many catheter-related bloodstream infections (CRBSIs) are preventable, measures to reduce these infections are not uniformly implemented...
  10. ncbi Sodium citrate versus heparin catheter locks for cuffed central venous catheters: a single-center randomized controlled trial
    Albert Power
    Haemodialysis Research Group, Imperial College Kidney and Transplant Institute, West London Renal and Transplant Centre, Hammersmith Hospital, London, UK
    Am J Kidney Dis 53:1034-41. 2009
    ..Studies of its use as a catheter lock have suggested its efficacy in preventing infection and bleeding complications compared with sodium heparin...
  11. ncbi Risk factors for catheter-related thrombosis in cancer patients
    M E T Tesselaar
    Department of Clinical Oncology, Leiden University Medical Center, P O Box, Albinusdreef 2, Leiden ZA 2333, The Netherlands
    Eur J Cancer 40:2253-9. 2004
    ..Prophylaxis with anticoagulants is recommended for chest, but not for arm ports. Determination of plasma homocysteine levels may identify patients at an increased risk for thrombosis...
  12. ncbi Clinical and economic consequences of nosocomial catheter-related bacteriuria
    S Saint
    Division of General Medicine, University of Michigan Department of Internal Medicine, Ann Arbor, MI 48109 0376, USA
    Am J Infect Control 28:68-75. 2000
    b>Indwelling catheters are strongly associated with the development of bacteriuria, which can lead to significant morbidity in hospitalized patients...
  13. ncbi A randomized trial comparing povidone-iodine to a chlorhexidine gluconate-impregnated dressing for prevention of central venous catheter infections in neonates
    J S Garland
    St Joseph s Hospital, Milwaukee, WI 53210, USA
    Pediatrics 107:1431-6. 2001
    ..Neonates who require a central venous catheter (CVC) for prolonged vascular access experience high rates of catheter-related bloodstream infection (CRBSI)...
  14. ncbi Renal infarction and immune-mediated glomerulonephritis in sheep (Ovis aries) chronically implanted with indwelling catheters
    Varada P Rao
    Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts
    J Am Assoc Lab Anim Sci 45:14-9. 2006
    ....
  15. ncbi Management of malignant pleural effusions
    Rachel Bennett
    Department of Respiratory Medicine, Southmead Hospital, North Bristol NHS Trust, Bristol, UK
    Curr Opin Pulm Med 11:296-300. 2005
    ..Although malignant pleural effusions are a common medical problem, research into their optimal management remains sparse. The aim of this review is to summarise recent developments in this area...
  16. ncbi Spontaneous migration of a Port-a-Cath catheter into ipsilateral jugular vein in two patients with severe cough
    Pei Yu Wu
    Department of Anesthesiology, National Taiwan University Hospital, Taipei, Taiwan
    Ann Vasc Surg 19:734-6. 2005
    ..Before a new course of chemotherapy or encountering symptoms of migration, obtaining a chest roentgenogram is essential to provide early detection and repositioning management of a migrated catheter...
  17. ncbi Local infiltration of anaesthesia with subpectoral indwelling catheters after immediate breast reconstruction with implants: a pilot study
    Zana Turan
    Department of Plastic and Reconstructive Surgery, Orebro University Hospital, Orebro
    Scand J Plast Reconstr Surg Hand Surg 40:136-9. 2006
    ..The oral consumption of opioids was significantly lower in patients with subpectoral indwelling catheters. The hospital stay was reduced in patients with subpectoral indwelling catheters...
  18. ncbi Purple urine bag syndrome: a rare and interesting phenomenon
    Noriko Soffi Harun
    Department of Medicine, Raja Isteri Pengiran Anak Saleha Hospital, Bandar Seri Begawan, BA 1710, Brunei Darussalam
    South Med J 100:1048-50. 2007
    ..Tryptophan metabolism is involved in the pathogenesis. We present two cases of this rare and interesting phenomenon and discuss the underlying pathogenesis...
  19. ncbi Prevention of intravascular catheter-related infections
    L A Mermel
    Division of Infectious Diseases, Rhode Island Hospital and Brown University School of Medicine, Providence 02903, USA
    Ann Intern Med 132:391-402. 2000
    ..To review the literature on prevention of intravascular catheter-related infections...
  20. ncbi Use of ethanol lock therapy to reduce the incidence of catheter-related bloodstream infections in home parenteral nutrition patients
    Marianne T Opilla
    Department of Nursing, Nutrishare, Inc, Elk Grove, California, USA
    JPEN J Parenter Enteral Nutr 31:302-5. 2007
    ..To reduce the incidence of infection in frequently infected HPN patients, prophylactic ethanol lock therapy (ELT) was initiated...
  21. ncbi A new simplified one port laparoscopic technique of peritoneal dialysis catheter placement with intra-abdominal fixation
    Haralampos V Harissis
    Department of Surgery, University Hospital of Ioannina, Panepistimiou Av, Ioannina 45500, Greece
    Am J Surg 192:125-9. 2006
    ..Various laparoscopic techniques have been described for the insertion of peritoneal dialysis catheters. However, most use 3 to 4 ports, thus multiplying the potential risk for abdominal wall complications (hemorrhage, hernia, leaking)...
  22. ncbi Comparison between the jugular and subclavian vein as insertion site for central venous catheters: microbiological aspects and risk factors for colonization and infection
    Geraldo Sadoyama
    Laboratory of Microbiology ARIMP Federal University of Uberlândia, Uberlandia MG, Brazil
    Braz J Infect Dis 7:142-8. 2003
    ..Health professionals should be aware of this potential source of infection at the CVC insertion site...
  23. ncbi Vascular access for dialysis in the intensive care unit
    Bernard Canaud
    Department of Nephrology, Intensive Care Units, Renal Research and Training Institute, Lapeyronie University Hospital, CHU Montpellier, 34295 France
    Best Pract Res Clin Anaesthesiol 18:159-74. 2004
    ..This 'lifeline' of chronic renal failure patients may be maintained by preventing inflammation, infection and thrombosis of the superficial vessels of the arm and forearm of patient...
  24. ncbi The azygos system as a rare alternative for chronic indwelling catheters placement
    Mireille A Moise
    Cleveland Clinic Foundation Main Campus, Cleveland, Ohio 44125, USA
    J Vasc Surg 50:655-8. 2009
    Chronic indwelling catheters are plagued with a high rate of complications, including infection, central venous occlusion, or thrombosis...
  25. ncbi Bacillus cereus central line infection in an immunocompetent child with hemophilia
    Poyyapakkam R Srivaths
    Tulane University School of Medicine, Huey P Long Medical Center, Department of Pediatrics, New Orleans, Louisiana, USA
    J Pediatr Hematol Oncol 26:194-6. 2004
    ..The authors report a case of Bacillus cereus infection of a central line in an immunocompetent patient with hemophilia, which required line removal for complete cure...
  26. ncbi Complications of indwelling catheters in cystic fibrosis: a 10-year review
    M L Aitken
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, School of Medicine, University of Washington, Seattle 98195, USA
    Chest 118:1598-602. 2000
    ..We attempted to determine the type and incidence of catheter complications so that CF patients could be fully informed of the risks prior to placement of these catheters...
  27. ncbi Vascular catheter site care: the clinical and economic benefits of chlorhexidine gluconate compared with povidone iodine
    Nathorn Chaiyakunapruk
    Pharmaceutical Outcomes Research and Policy Program, Department of Pharmacy, University of Washington, Seattle, WA 98195 7630, USA
    Clin Infect Dis 37:764-71. 2003
    ..Use of chlorhexidine gluconate in place of the current standard solution for vascular catheter site care is a simple and cost-effective method of improving patient safety in the hospital setting...
  28. ncbi Urethral versus suprapubic catheter: choosing the best bladder management for male spinal cord injury patients with indwelling catheters
    H K Katsumi
    Department of Urology, University of California Irvine, Orange, CA 92868, USA
    Spinal Cord 48:325-9. 2010
    ..The objective of this study was to compare the complications associated with urethral catheter (UC) versus suprapubic tube (SPT) in patients with SCI...
  29. ncbi Vascular access and all-cause mortality: a propensity score analysis
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, Melbourne, Victoria, Australia
    J Am Soc Nephrol 15:477-86. 2004
    ..Reducing catheter use and increasing the proportion of patients commencing hemodialysis with a mature AVF remain important clinical objectives...
  30. ncbi Totally implantable central venous access ports for long-term chemotherapy. A prospective study analyzing complications and costs of 333 devices with a minimum follow-up of 180 days
    R Biffi
    Division of General Surgery, European Institute of Oncology, Milano, Italy
    Ann Oncol 9:767-73. 1998
    ..This prospective study deals with the complications and global costs of central venous ports connected to a Groshong catheter for deliverance of long-term chemotherapy...
  31. ncbi A laparoscopic method for optimal peritoneal dialysis access
    John H Crabtree
    Department of Surgery, Southern California Permanente Medical Group, Kaiser Permanente Bellflower Medical Center, Bellflower, California 90706, USA
    Am Surg 71:135-43. 2005
    ..One pericannular hernia occurred in the open group. Catheter mechanical dysfunction attributable to the surgical technique can nearly be eliminated through adjunctive procedures made possible only by a laparoscopic approach...
  32. ncbi Mass spectrometry and scanning electron microscopy study of silicone tunneled dialysis catheter integrity after an exposure of 15 days to 60% ethanol solution
    Sophie Guenu
    University of Clermont 1, Laboratoire de Chimie Analytique et Spectrométrie de Masse, UFR Pharmacie, 63001 Clermont Ferrand, France
    Rapid Commun Mass Spectrom 21:229-36. 2007
    ..These results should allow the development of clinical trials to assess the efficacy of the 60% ethanol lock technique in preventing or controlling the infectious complications of silicone dialysis catheters...
  33. pmc Prevention of catheter-associated urinary tract infection
    Barbara W Trautner
    Department of Medicine, Michael E DeBakey Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas, USA
    Curr Opin Infect Dis 18:37-41. 2005
    ..Considerable work is being done in this area, but little clinical progress has been made. The purpose of this review is to analyze recent publications concerning prevention of catheter-associated urinary tract infection...
  34. ncbi Effect of covalently bound heparin coating on patency and biocompatibility of long-term indwelling catheters in the rat jugular vein
    Patricia L Foley
    Center for Comparative Medicine, University of Virginia, Charlottesville 22908, USA
    Comp Med 52:243-8. 2002
    ..Taken together, these results indicate that coating catheters with covalently bound heparin molecules can significantly prolong patency and cause less pathologic damage to the catheterized vessel...
  35. ncbi Mini-laparoscopy-assisted placement of Tenckhoff catheters: an improved technique to facilitate peritoneal dialysis
    Charlotte A Batey
    Division of Urology, Department of Surgery, University of Kentucky, 800 Rose Street, Lexington, KY 40536 0084, USA
    J Endourol 16:681-4. 2002
    ....
  36. pmc Escherichia coli 83972 inhibits catheter adherence by a broad spectrum of uropathogens
    Barbara W Trautner
    Department of Medicine, Infectious Diseases Section, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Urology 61:1059-62. 2003
    ..To explore this phenomenon further, we investigated in vitro whether E. coli 83972 could likewise inhibit catheter colonization by gram-negative and fungal uropathogens (Providencia stuartii, uropathogenic E. coli, and Candida albicans)...
  37. ncbi Antimicrobial lock solutions for the prevention of infections associated with intravascular catheters in patients undergoing hemodialysis: systematic review and meta-analysis of randomized, controlled trials
    Dafna Yahav
    Department of Medicine E, Rabin Medical Center, Beilinson Campus, 49100 Petah Tiqva, Israel
    Clin Infect Dis 47:83-93. 2008
    ..Prevention of catheter-related bloodstream infections in patients undergoing hemodialysis by use of antimicrobial catheter lock solutions has been examined in several trials, but no consensus is available for clinical practice...
  38. ncbi Ethanol lock solution as an adjunct treatment for preventing recurrent catheter-related sepsis--first case report in dialysis setting
    Clement Ackoundou-N'Guessan
    Nephrol Dial Transplant 21:3339-40. 2006
  39. ncbi Species interactions in mixed-community crystalline biofilms on urinary catheters
    Sarah M Macleod
    Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    J Med Microbiol 56:1549-57. 2007
    ..mirabilis and some of the other urinary tract organisms, the effects are temporary and whatever the pre-existing urinary microbiota, infection with P. mirabilis is thus likely to lead to catheter encrustation and blockage...
  40. pmc Pre-inoculation of urinary catheters with Escherichia coli 83972 inhibits catheter colonization by Enterococcus faecalis
    Barbara W Trautner
    Department of Medicine Infectious Diseases Section, Veterans Affairs Medical Center, Houston, TX, USA
    J Urol 167:375-9. 2002
    ..Enterococcus was chosen for these trials since it is a common urinary pathogen in patients with an indwelling urinary catheter...
  41. pmc Coating urinary catheters with an avirulent strain of Escherichia coli as a means to establish asymptomatic colonization
    Barbara W Trautner
    Department of Medicine, Infectious Diseases Section, Center for Prostheses Infection, Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Infect Control Hosp Epidemiol 28:92-4. 2007
    ..Ten of 12 subjects were successfully colonized for 14 days or more. The rate of symptomatic UTI during colonization was 0.15 per 100 patient-days...
  42. ncbi Screening cystoscopy and biopsy in patients with neuropathic bladder and chronic suprapubic indwelling catheters: is it valid?
    R Hamid
    Spinal Injuries Unit, Royal National Orthopaedic Hospital, Stanmore, Middlesex, United Kingdom
    J Urol 170:425-7. 2003
    ..Despite this practice the test has not been fully validated to date. We analyzed our experience with this screening test and explored its validity when applied to our patients...
  43. ncbi Hospital outbreak of Burkholderia stabilis bacteraemia related to contaminated chlorhexidine in haematological malignancy patients with indwelling catheters
    S T Heo
    Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Korea
    J Hosp Infect 70:241-5. 2008
    ..Following identification of the source of contamination, strict controls regarding surveillance cultures for disinfectants have been enforced. No further B. stabilis infections have been found in the hospital...
  44. ncbi Polypoid cystitis unrelated to indwelling catheters: a report of eight patients
    Suleyman Kilic
    Department of Urology, Inonu University Medical Faculty, Turgut Ozal Medical Center, Malatya, Turkey
    Int Urol Nephrol 34:293-7. 2002
    ..The final urologic examinations which were done currently, were normal. In conclusion, PC is a benign lesion and should be considered in the differential diagnosis of transitional cell carcinoma of the bladder...
  45. ncbi Peripheral Teflon catheters: factors determining incidence of phlebitis and duration of cannulation
    Oliver A Cornely
    Department I of Internal Medicine, Cologne University Hospital, Germany
    Infect Control Hosp Epidemiol 23:249-53. 2002
    ..Risk factors for catheter-related phlebitis were assessed at a single tertiary-care institution where no routine change policy for peripheral intravenous catheters is in place...
  46. ncbi Indwelling catheters for the management of malignant ascites
    A Lee
    Department of Geriatric Medicine, Tan Tock Seng Hospital, Singapore
    Support Care Cancer 8:493-9. 2000
    ..We carried out a retrospective review of all patients who had indwelling catheters inserted for the management of symptomatic malignant ascites over a 4-year period...
  47. ncbi Percutaneous vs. surgical placement of hepatic artery indwelling catheters for regional chemotherapy
    Luca Aldrighetti
    Department of Surgery, Scientific Institute H San Raffaele, Vita Salute San Raffaele University, Milan, Italy
    Hepatogastroenterology 49:513-7. 2002
    ..The aim of the present study is the comparative analysis of surgical and percutaneous transaxillary approaches to implant a catheter into the hepatic artery for intra-arterial hepatic chemotherapy with floxuridine...
  48. ncbi Randomized, multicenter trial of fluorouracil plus leucovorin administered either via hepatic arterial or intravenous infusion versus fluorodeoxyuridine administered via hepatic arterial infusion in patients with nonresectable liver metastases from colore
    M Lorenz
    Department of General and Vascular Surgery, Johann Wolfgang Goethe Universit at, Frankfurt am Main, Germany
    J Clin Oncol 18:243-54. 2000
    ....
  49. ncbi Tesio-Caths provide effective and safe long-term vascular access
    Neill D C Duncan
    Renal and Transplant Unit, St Mary s Hospital, London, UK
    Nephrol Dial Transplant 19:2816-22. 2004
    ..We report the large-scale use of Tesio-Caths, a twin-line single-lumen central venous catheter, to maximize dialysis adequacy where formation of an arteriovenous fistula was not possible...
  50. ncbi Shorter break-in period is a viable option with tighter PD catheter securing during the insertion
    Ajay P Sharma
    Department of Paediatrics, Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    Nephrology (Carlton) 13:672-6. 2008
    ..Recent single-arm studies reported good catheter outcome despite shorter break-in periods after peritoneal dialysis (PD) catheter insertions. These results were attributed to tight catheter securing during the insertions...
  51. ncbi Placement of a permanent tunneled peritoneal drainage catheter for palliation of malignant ascites: a simplified percutaneous approach
    Ted D Barnett
    Department of Diagnostic Imaging, F F Thompson Hospital and The Sands Cancer Center, Canandaigua, New York 14424, USA
    J Vasc Interv Radiol 13:379-83. 2002
    ..To report a simple, minimally invasive method of palliative drainage of symptomatic malignant ascites, which allows patients to avoid repeated trips to the hospital for paracentesis...
  52. ncbi Use of a pleural implantable access system for the management of malignant pleural effusion: the Institut Curie experience
    Catherine Daniel
    Institut Curie, Paris, France
    Ann Thorac Surg 84:1367-70. 2007
    ..The authors report the first experience of a pleural implantable access system for the treatment of recurrent symptomatic malignant pleural effusion...
  53. ncbi Catheter-related infection in critically ill patients
    Leonardo Lorente
    Department of Intensive Care, Hospital Universitario de Canarias, Ofra s n La Cuesta, 38320 La Laguna, Santa Cruz de Tenerife, Spain
    Intensive Care Med 30:1681-4. 2004
    ..To describe the incidence of the catheter-related local infection (CRLI) and catheter-related bloodstream infection (CRBSI) of central venous catheters (CVCs) and arterial catheters (ACs)...
  54. ncbi Microsurgery in children for creation of arteriovenous fistulas in renal and non-renal diseases
    Pierre Bourquelot
    Angioaccess Department, Clinique Jouvenet, Paris, France
    Ther Apher Dial 7:498-503. 2003
    ..Microsurgery is mandatory for creation of arteriovenous fistulas, the best form of angioaccess for children treated by hemodialysis or requiring repeated access to blood in various non-renal diseases...
  55. ncbi The management of acute urinary retention in France: a cross-sectional survey in 2618 men with benign prostatic hyperplasia
    Francois Desgrandchamps
    Department of Urology, Saint Louis Hospital, 1 avenue Claude Vellefaux, 75475 Paris Cedex 10, France
    BJU Int 97:727-33. 2006
    ..To evaluate current practice in the management of acute urinary retention (AUR) in men with benign prostatic hyperplasia (BPH) in France...
  56. ncbi Bacterial biofilms in patients with indwelling urinary catheters
    David J Stickler
    Cardiff School of Biosciences, Main Building, Cardiff University, Museum Avenue, Cardiff CF103TL, UK
    Nat Clin Pract Urol 5:598-608. 2008
    ..Many bacterial species colonize indwelling catheters as biofilms, inducing complications in patients' care...
  57. ncbi Ethanol disinfection of plastic-adherent micro-organisms
    S T Chambers
    Department of Pathology, Christchurch School of Medicine, University of Otago, New Zealand
    J Hosp Infect 63:193-6. 2006
    ..These results suggest that in contrast to log phase organisms, which are killed by ethanol/water solutions in seconds, plastic-adherent organisms are more resistant to the bactericidal activity of ethanol...
  58. ncbi Meta-analysis: methods for diagnosing intravascular device-related bloodstream infection
    Nasia Safdar
    University of Wisconsin Medical School, Madison, Wisconsin, USA
    Ann Intern Med 142:451-66. 2005
    ..No consensus exists on the best methods for diagnosis of intravascular device (IVD)-related bloodstream infection...
  59. ncbi Vascular access practice patterns in the New Zealand hemodialysis population
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Center, Melbourne, Victoria, Australia
    Am J Kidney Dis 43:696-704. 2004
    ..Physician practice patterns may have a strong influence on access type. We assessed differences in vascular access practice patterns across all treating centers in New Zealand...
  60. ncbi Effect of change in vascular access on patient mortality in hemodialysis patients
    Michael Allon
    University of Alabama, Birmingham, AL, USA
    Am J Kidney Dis 47:469-77. 2006
    ..However, catheter-dependent patients also differ from those with an AV access in several clinical features, and these differences may themselves contribute to their excess mortality...
  61. ncbi Ethanol-lock technique for persistent bacteremia of long-term intravascular devices in pediatric patients
    Wes Onland
    Department of Pediatrics, Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands
    Arch Pediatr Adolesc Med 160:1049-53. 2006
    ..To use the ethanol-lock technique (in conjunction with systemic antibiotics) to salvage central lines from removal and to prevent persistence of catheter-related infections among pediatric patients with long-term intravascular devices...
  62. ncbi Recombinant tissue plasminogen activator infusion for hemodialysis catheter clearance
    Oluwatoyin F Bamgbola
    Department of Pediatrics, Division of Pediatric Nephrology, Oklahoma University Health Science Center, 940 NE 13th Street, Oklahoma, OK 73104, USA
    Pediatr Nephrol 20:989-93. 2005
    ..It may serve as an alternative method of administration to local instillation and may be used to restore patency before resorting to surgical revisions...
  63. ncbi Increased use of catheters as vascular access: is it justified by patients' clinical conditions?
    A Di Benedetto
    NephroCare Italy, Naples, Italy
    J Vasc Access 8:21-7. 2007
    ..The aim of this study was to evaluate the time patients in four European countries have to wait before undergoing their first surgery for VA (AVF or graft)...
  64. ncbi Enoxaparin for the prevention of venous thromboembolism associated with central vein catheter: a double-blind, placebo-controlled, randomized study in cancer patients
    Melina Verso
    Sezione di Medicina Interna e Cardiovascolare, Dipartimento di Medicina Interna, Universita di Perugia, Via Enrico Dal Pozzo, 06123 Perugia, Italy
    J Clin Oncol 23:4057-62. 2005
    ..The aim of this study was to evaluate the efficacy and safety of the low molecular weight heparin, enoxaparin, in the prevention of VTE...
  65. ncbi Complications of the ethanol-lock technique in the treatment of central venous catheter sepsis
    Jane Laird
    J Infect 51:338. 2005
  66. ncbi Use of a "composite" vascular access graft in a young child on hemodialysis
    Keith K Lau
    Department of Pediatrics, University of California, Davis, Sacramento, California 95817, USA
    Hemodial Int 11:190-2. 2007
    ..This modification may overcome the kinking complication associated with use of the polyurethane graft and the resulting thrombosis...
  67. ncbi Antimicrobial coating of central venous catheters: show me the data
    Elias Anaissie
    Crit Care Med 35:1197-9. 2007
  68. ncbi Randomized placebo-controlled study of low-dose warfarin for the prevention of central venous catheter-associated thrombosis in patients with cancer
    Stephen Couban
    Department of Medicine, Dalhousie University and Queen Elizabeth II Health Sciences Centre, Room 417, Bethune Bldg, 1278 Tower Rd, Halifax, Nova Scotia B3H 2Y9, Canada
    J Clin Oncol 23:4063-9. 2005
    ..In this multicenter, randomized, placebo-controlled clinical trial, we studied whether warfarin 1 mg daily reduces the incidence of symptomatic central venous catheter (CVC) -associated thrombosis in patients with cancer...
  69. ncbi Prevention of catheter-related bloodstream infections: analysis of studies published between 2002 and 2005
    P Gastmeier
    Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany
    J Hosp Infect 64:326-35. 2006
    ..Simple interventions are often useful for reducing CR-BSI rates and the opportunities to decrease CR-BSI rates appear to be greatest when multi-module programmes are applied. An average reduction of more than 50% seems to be possible...
  70. ncbi How to improve dialysis adequacy in patients with vascular access problems
    S Mandolfo
    Renal Unit, Maggiore Hospital, Lodi, Italy
    J Vasc Access 7:53-9. 2006
    ..Recent developments in a new class of highly effective hemodialyzer due to dialysate distribution, has opened up interesting opportunities in terms of dialysis adequacy in patients with reduced VA flow rate...
  71. pmc Accidental catheter removal in critically ill patients: a prospective and observational study
    Leonardo Lorente
    Staff Intensivist, Department of Intensive Care, Hospital Universitario de Canarias, Tenerife, Spain
    Crit Care 8:R229-33. 2004
    ..The objective of the present study was to analyze the incidence of ACR for all types of catheters in the ICU...
  72. ncbi Haemodialysis vascular access problems in Canada: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS II)
    David C Mendelssohn
    Division of Nephrology, Humber River Regional Hospital, University of Toronto, Weston, ON, Canada
    Nephrol Dial Transplant 21:721-8. 2006
    ..Vascular access practice patterns are reported for a Canadian cohort of patients from the Dialysis Outcomes and Practice Patterns Study (DOPPS II)...
  73. ncbi The role of new technologies in treating children and adolescents with type 1 diabetes mellitus
    S Shalitin
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tikva, Israel
    Pediatr Diabetes 8:72-9. 2007
    ..This review focuses on the new technologies which have been developed for treating children and adolescents with type 1 diabetes...
  74. ncbi Vascular access for hemodialysis: the impact on morbidity and mortality
    Biagio R Di Iorio
    Nephrology and Dialysis Unit, A Landolfi Hospital of Solofra, Avellino, Italy
    J Nephrol 17:19-25. 2004
    ..This study, using registry data, evaluated the morbidity and mortality risk associated with the use of different permanent vascular access (VA) in a HD patient cohort...
  75. ncbi Randomized, clinical trial comparison of trisodium citrate 30% and heparin as catheter-locking solution in hemodialysis patients
    Marcel C Weijmer
    Department of Nephrology, Free University Medical Center, Amsterdam, The Netherlands
    J Am Soc Nephrol 16:2769-77. 2005
    ..010). TSC 30% improves overall patency rates and reduces catheter-related infections and major bleeding episodes for both tunneled and untunneled hemodialysis catheters. Flow problems are not reduced...
  76. ncbi Use of an ethanol lock to prevent catheter-related infections in children with short bowel syndrome
    Elisabeth Mouw
    Department of Clinical Pharmacy and Outcome Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    J Pediatr Surg 43:1025-9. 2008
    ..Treatment strategies include antibiotic- and ethanol-containing locks, with CVC removal if the CRI cannot be cleared. Ethanol lock therapy has been reported for CRI treatment in children but not for CRI prevention...
  77. ncbi Delayed compared with immediate use of peritoneal catheter in pediatric peritoneal dialysis
    U D Patel
    Department of Internal Medicine and Department of Pediatrics and Communicable Diseases, University of Michigan Health System, Ann Arbor, Michigan, USA
    Adv Perit Dial 17:253-9. 2001
    ..On the other hand, delayed use may be associated with a greater risk of infection. Further studies involving larger numbers of children will be necessary to confirm these findings...
  78. ncbi Ethanol lock technique: review of the literature
    Melissa Maiefski
    Department of Pharmaceutical and Nutrition Care, Nebraska Medical Center, Omaha, Nebraska 68198 4031, USA
    Infect Control Hosp Epidemiol 30:1096-108. 2009
    ..Definitive catheter integrity data are limited. Clinical trials report tolerable adverse events with ethanol locks, as well as encouraging results for prevention and treatment of CLA BSI...
  79. ncbi Successful use of Tesio catheters in pediatric patients receiving chronic hemodialysis
    R D Sheth
    Department of Pediatrics, Baylor College of Medicine and Texas Children s Hospital, Houston, TX, USA
    Am J Kidney Dis 38:553-9. 2001
    ..We conclude that Tesio catheters provide superior performance compared with DL catheters in terms of catheter survival, infection rates, and duration of adequate performance...
  80. ncbi Echocardiographic evaluation of umbilical venous catheter placement
    Anne Ades
    Department of Neonatology, Children s Hospital of Philadelphia, PA 19104, USA
    J Perinatol 23:24-8. 2003
    ..To compare techniques for guiding and confirming placement of umbilical venous catheters (UVCs) using two-dimensional echocardiography...
  81. ncbi Minocycline-ethylenediaminetetraacetate lock solution for the prevention of implantable port infections in children with cancer
    Ioannis Chatzinikolaou
    Division of Internal Medicine, Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
    Clin Infect Dis 36:116-9. 2003
    ..M-EDTA is a promising lock solution in long-term catheters...
  82. ncbi Type of vascular access and mortality in U.S. hemodialysis patients
    R K Dhingra
    Division of Nephrology, University of Michigan Medical Center, Ann Arbor, Michigan, USA
    Kidney Int 60:1443-51. 2001
    ..Vascular access (VA) complications account for 16 to 25% of hospital admissions. This study tested the hypothesis that the type of VA in use is correlated with overall mortality and cause-specific mortality...
  83. ncbi Seven cases of surgical native valve endocarditis caused by coagulase-negative staphylococci: An underappreciated disease
    P S Miele
    Washington Hospital Center, Washington, DC 20010, USA
    Am Heart J 142:571-6. 2001
    ..The increasing use of intravascular access devices in the community may herald an increase in the incidence of CNS-NVE. A high index of diagnostic suspicion in the appropriate clinical setting is critical for optimal management...
  84. ncbi A randomized controlled trial of topical exit site mupirocin application in patients with tunnelled, cuffed haemodialysis catheters
    David Wayne Johnson
    Department of Renal Medicine, Princess Alexandra Hospital, Brisbane, Australia
    Nephrol Dial Transplant 17:1802-7. 2002
    ..Whether mupirocin offers any additional protection against infection in patients with tunnelled, cuffed haemodialysis catheters has not been studied...
  85. ncbi Intermittent versus indwelling catheters for older patients with hip fractures
    Inger Johansson
    Division for Health and Caring Sciences, Karlstad University, SE 651 88 Karlstad, Sweden
    J Clin Nurs 11:651-6. 2002
    ..fracture before and after surgery, to assess whether the decision to use intermittent catheters instead of indwelling catheters was adopted and to test the hypothesis that hospital stay is significantly longer for patients with UTI ..
  86. ncbi Community-care waiting list for persons with spinal cord injury
    S Vaidyanathan
    Spinal Injuries Unit, District General Hospital, Southport, Merseyside, UK
    Spinal Cord 39:584-8. 2001
    ..believe that a community care waiting list for bladder management will help to provide optimum care for neuropathic bladder and, hopefully, reduce the complications related to long-term indwelling catheters in spinal cord injury patients.
  87. ncbi A prospective double-blind randomized trial comparing intraluminal ethanol with heparinized saline for the prevention of catheter-associated bloodstream infection in immunosuppressed haematology patients
    Joanne Sanders
    Department of Pathology, Christchurch School of Medicine and Health Sciences, Otago University, Christchurch, New Zealand
    J Antimicrob Chemother 62:809-15. 2008
    ..The aim of this study was to prospectively evaluate the use of intraluminal ethanol for the prevention of catheter-associated bloodstream infection (CABSI) in immunosuppressed haematology patients...
  88. ncbi Effective flow performances and dialysis doses delivered with permanent catheters: a 24-month comparative study of permanent catheters versus arterio-venous vascular accesses
    Bernard Canaud
    Department of Nephrology and Dialysis Research and Training Institute, Lapeyronie University Hospital, CHRU Montpellier, Montpellier, France
    Nephrol Dial Transplant 17:1286-92. 2002
    ..There is limited data comparing the long-term dialysis adequacy delivered with permanent catheters vs arterio-venous vascular accesses (AVA)...
  89. ncbi Purple urinary bag syndrome: a harmless but alarming problem
    John Robinson
    Continence Advisory Service, Morecambe Bay Primary Health Care Trust NHS, Morecambe
    Br J Community Nurs 8:263-6. 2003
    ..Over a period of time this discolouration then impregnates their catheter. This condition also produces a strong odour, and as air temperature increases, so does the smell. This condition is known as purple urinary bag syndrome or PUBS...
  90. ncbi Central venous lines for chronic hemodialysis: survey of the Midwest Pediatric Nephrology Consortium
    Rudolph P Valentini
    Division of Nephrology, The Carman and Ann Adams Department of Pediatrics, Children s Hospital of Michigan, Wayne State University School of Medicine, Detroit, MI, USA
    Pediatr Nephrol 23:291-5. 2008
    ..As treatment strategies varied greatly, future prospective studies are needed to determine the effectiveness of each individual therapy...
  91. ncbi In vitro and in vivo efficacy of catheters impregnated with antiseptics or antibiotics: evaluation of the risk of bacterial resistance to the antimicrobials in the catheters
    L A Sampath
    Department of Surgery, College of Physicians and Surgeons, Columbia University, New York City, New York 10032, USA
    Infect Control Hosp Epidemiol 22:640-6. 2001
    ..05). CONCLUSIONS: Antiseptic and antibiotic catheters exhibit similar efficacy; however, when challenged with a rifampin-resistant strain, the antibiotic catheter appeared to be more susceptible to colonization than the antiseptic device...
  92. ncbi Managing the complications of long-term tunneled dialysis catheters
    Donald Schon
    Arizona Kidney Disease and Hypertension Center Surgery Center and Renal Section, University of Arizona Health Sciences Center, Phoenix, Arizona 85012 2319, USA
    Semin Dial 16:314-22. 2003
    ..The topics reviewed include stenoses, thrombus formation, fibrin sheath formation, infections, and vascular ingrowth. Suggestions for management are also discussed...
  93. ncbi Mechanical complications related to indwelling central venous catheter in pediatric hematology/oncology patients
    G Fratino
    Department of Paediatric Surgery, G Gaslini Institute, L go G Gaslini, 5 I 16147 Genoa, Italy
    Pediatr Hematol Oncol 18:317-24. 2001
    ..Moreover, the experience of administering a systemic low-dosage thrombolytic therapy demonstrates new prospects of reducing CVC replacement by restoring CVC viability...
  94. ncbi Effect of antimicrobial locks for tunneled hemodialysis catheters on bloodstream infection and bacterial resistance: a quality improvement report
    Saib A Abbas
    Department of Renal Medicine, Middlemore Hospital, Counties Manukau District Health Board, Manukau, New Zealand
    Am J Kidney Dis 53:492-502. 2009
    ..Catheter-restricted antimicrobial lock (AML) use reduces catheter-associated bloodstream infection (CA-BSI) in clinical trial settings, but may not be as effective in clinical settings and may increase bacterial resistance...
  95. ncbi A model of catheter-associated urinary tract infection initiated by bacterial contamination of the catheter tip
    Jessica M T Barford
    Medical Microbiology, Centre for Infection, Division of Cellular and Molecular Medicine, St George s, University of London, London, UK
    BJU Int 102:67-74. 2008
    ..To examine the microbial colonization of urinary catheters that have been used by patients, to model catheter colonization in vitro and thus provide information about the way bacteria gain access to the bladder during catheterization...
  96. ncbi Comparison of various antimicrobial agents as catheter lock solutions: preference for ethanol in eradication of coagulase-negative staphylococcal biofilms
    Yue Qu
    School of Applied Sciences, RMIT University, Plenty Road, Bundoora, Victoria 3083, Australia
    J Med Microbiol 58:442-50. 2009
    ....
  97. ncbi Selective performance of prophylactic omentopexy during laparoscopic implantation of peritoneal dialysis catheters
    John H Crabtree
    Department of Surgery, Southern California Permanente Medical Group, Kaiser Permanente Bellflower Medical Center, California 90706, USA
    Surg Laparosc Endosc Percutan Tech 13:180-4. 2003
    ..Actuarial analysis demonstrates that an operative strategy of selectively performing omentopexy for redundant omentum significantly improves catheter survival free of flow dysfunction (P < 0.0001)...
  98. ncbi Temporary hemodialysis catheters as a long-term vascular access in chronic hemodialysis patients
    Rafael Ponikvar
    Department of Nephrology, University Medical Center Ljubljana, University of Ljubljana, Ljubljana, Slovenia
    Ther Apher Dial 9:250-3. 2005
    ..The main reasons for catheter exchange or removal were malfunction and mechanical damage of the catheter...
  99. ncbi Long-term management of the tunneled venous catheter
    Orfeas Liangos
    Department of Medicine, Tufts University School of Medicine, Caritas St Elizabeth s Medical Center, Boston, Massachusetts 02135, USA
    Semin Dial 19:158-64. 2006
    ..However, these measures should not detract from the goal of avoiding or limiting the long-term use of catheters, thereby optimizing vascular access management by ensuring the timely availability of functioning arteriovenous fistulas...
  100. ncbi Treatment of refractory central vein stenosis in hemodialysis patients with stents
    Ivan D Maya
    Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Semin Dial 20:78-82. 2007
    ..However, long-term symptomatic relief can be achieved with multiple subsequent interventions in many patients...
  101. ncbi Use of LifeSite port systems for hemodialysis in Germany
    M Hollenbeck
    Department of Nephrology and Rheumatology, Knappschaftskrankenhaus, Bottrop, Germany
    Clin Nephrol 64:138-43. 2005
    ..We investigated complications in patients with exhausted access sites and a high comorbidity...

Research Grants62

  1. MOLECULAR MECHANISMS OF SEPTIC SHOCK
    JACK HAWIGER; Fiscal Year: 2003
    ..In many cases these bacterial infections occur in the setting of indwelling catheters coated with bacterial biofilms following their insertion for neonatal parenteral nutrition, accident- and ..
  2. Chronic Electrical Stimulation to Reduce Bladder Hyperreflexia after SCI
    Kenneth J Gustafson; Fiscal Year: 2012
    ..In persons with indwelling catheters it is expected to reduce the number and intensity of bladder spasms as well as average bladder pressures in ..
  3. Effects of Cannabinoids on the Immune Response to Murine Systemic Candidiasis
    NANCY ELIZABETH BUCKLEY-NIEVES; Fiscal Year: 2012
    ..The present proposal will investigate the effects of THC, its related compound 2-arachidonoylglycerol and the peripheral cannabinoid receptor on the immune responses to a systemic Candida albicans infection in mice. ..
  4. Innovative technologies to effectively treat Multi-drug resistant and/or biofilm-
    Jie Wen; Fiscal Year: 2010
    ..0 M people in the U.S. each year and costs more than $11.0 B to the healthcare providers. Wound care and indwelling catheters, the two most commonly associated areas of infection, experienced a surge of antimicrobial devices in the ..
  5. Spinal cord injury: Targeting local inhibition to improve outcome
    Linda J Noble; Fiscal Year: 2010
    ..residual walking ability, tolerance, withdrawal syndrome, and infectious and other complications related to indwelling catheters;and posterior rhizotomy which can cause weakness, sensory loss, urinary dysfunction, sexual dysfunction, ..
  6. Delayed Onset of Biofilm Formation and CAUTI with Superhydrophobic Catheters
    Sanjiv Lalwani; Fiscal Year: 2011
    ..urinary tract infections (CAUTI) occur in >40&of the 21-50% patients that are administered indwelling catheters, annually costing a staggering $421-$451 million in medical intervention, antimicrobial treatments and ..
  7. Optimal Amino Acid Nutrition in Sepsis
    Robert R Wolfe; Fiscal Year: 2012
    ..The specific aims will be tested in a chronically instrumented pig model prepared with indwelling catheters to enable sampling across the gut, liver, and muscle...
  8. Analysis of Novel Acinetobacter baumannii Adhesins
    Anthony A Campagnari; Fiscal Year: 2013
    ..infections such as pneumonia in intubated patients and urinary tract infections in patients with indwelling catheters. There have been occasional reports implicating A...
  9. EXPERIMENTAL MODEL FOR CHORIOAMNIONITIS AND PREMATURITY
    Michael Gravett; Fiscal Year: 2005
    ..associated uterine activity; (3) infuse proinflammatory cytokine IL-1beta into the amniotic cavity through indwelling catheters in the absence of infection...
  10. COATING OF URINARY PROTHESES TO PREVENT ENCRUSTATION
    Harmeet Sidhu; Fiscal Year: 2000
    ..Such devices could benefit urological patients, a population where >10% of hospitalizations require catheterization and stenting. ..
  11. Improving Indwelling Catheter Use to Reduce CAUTI in the Nursing Home
    Jerry H Gurwitz; Fiscal Year: 2013
    ..a) newly admitted NH residents (a "present on admission" catheter group);and (b) NH residents in whom indwelling catheters are placed within 14 days following admission to the facility (an "early placement" post-admission catheter ..
  12. NOVEL ACCESSORY FOR URINARY LEG BAGS
    SHANTHA SARANGAPANI; Fiscal Year: 1999
    Urinary drainage bags called leg bags are commonly used with permanent indwelling catheters in patients, with incontinence or chronic disabilities, at rehabilitation centers or hospitals...
  13. ENZYME-COATED URINARY PROSTHESES TO PREVENT ENCRUSTATION
    STEPHEN BARTELMEZ; Fiscal Year: 2004
    Use of indwelling catheters and stents long-term in the urinary tract is often limited due to the occurrence of encrustation and biofilm formation To date, there are no biomaterials used in the urinary tract that are completely ..
  14. ZYNPEPTIDES AS MODULATORS OF RESPONSES TO BIOMATERIALS
    Gregory Kopia; Fiscal Year: 1991
    ..as in renal dialysis), or chronic, in-dwelling catheters. Demonstration of the validity of this hypothesis would also support a general approach to site-specific modification of biological responses to implantable biomaterials...
  15. MICROBICIDAL PROTEINS FROM PLATELETS
    Michael Yeaman; Fiscal Year: 2000
    ..light of the increasing use of indwelling biomaterials such as artificial cardiac valves, prolonged use of indwelling catheters, and endovascular stents, the incidence of endovascular infections will likely continue to grow...
  16. Apoptosis Inducing to Enhance Tumor Targeting
    Ze Lu; Fiscal Year: 2004
    ..Second, ip therapy is associated with infection due to prolonged use of indwelling catheters and abdominal pain due to the high local drug concentrations...
  17. Antimicrobial Nanocoating
    R Dillingham; Fiscal Year: 2005
    ..g. indwelling catheters, central lines, prostheses and other invasive devices); and 2) treating dental and surgical instruments to ..
  18. Aqueous Vein Drain Tube
    John Swanson; Fiscal Year: 2002
    ..Other applications for this technology would include chronic indwelling catheters for drug delivery within the venous or suprachoroidal space for neuroprotective medications and antitumor ..
  19. INFECTION-RESISTANT POLYURETHANE MATERIALS
    Michael Szycher; Fiscal Year: 2001
    ..cPU polymer will be coated onto pre-formed indwelling catheters. Cipro will be dyed onto cPU-coated catheters using parameters from phase I...
  20. Animal Testing of a Blocking Antibody of PcrV
    Teiji Sawa; Fiscal Year: 2002
    ..aeruginosa infection in patients at high risk for this infection, including patients on ventilators, burn patients, patients with in-dwelling catheters, neutropenic patients, an patients with cystic fibrosis. ..
  21. INFECTION RESISTANT POLYURETHANE MATERIALS
    Michael Szycher; Fiscal Year: 1999
    ..with long-term infection resistance has applications in wa wide range of implantable devices, such as indwelling catheters, vascular grafts, stents, and as coatings on existing catheters...
  22. CQCH Internet Access to Digital Libraries
    James Dickson; Fiscal Year: 2005
    ..is as follows: A local physician sees a patient who has moved here from Elfrida and has a particular indwelling catheters that needs to be flushed...
  23. A TARGETED AMPHOTERICIN B PRODRUG FOR ANTIFUNGAL THERAPY
    SEAN O MALLEY; Fiscal Year: 2000
    ..patients, iv drug abusers, diabetics, severe burn patients, transplant recipients, and individuals with indwelling catheters. Ironically, it is because of the advent of medical advances in the use of antibiotics, chemotherapeutics, ..
  24. Self-Disinfecting Catheters
    CRAIG TURCHI; Fiscal Year: 2002
    ..In addition to urethral catheters this technology can be applied to other sites of biofilm growth including dialysis catheters, fluid conduits in medical equipment, and hospital waterlines. ..
  25. Prevention of Pseudomonas Infection with anti-PcrV
    EDWARD SPACK; Fiscal Year: 2001
    ..aervginosa infection in patients at high risk for this infection, including patients on ventilators, bum patients, patients with in-dwelling catheters, neutropenic patients, and patients with cystic fibrosis. ..
  26. EFFECT OF SEIZURE UPON ENERGY METABOLISM IN BRAIN
    ROBERT GUYNN; Fiscal Year: 1980
    ..Blood will be drawn from indwelling catheters placed under light anesthesia once the animal is awake...
  27. NON-INVASIVE BLOOD PRESSURE MEASUREMENT
    RUBEN BUNAG; Fiscal Year: 1980
    ..finally developed will be validated by comparison with phasic aortic pressure recorded simultaneously from indwelling catheters in trained awake normotensive and hypertensive rats...
  28. PREVENTION OF UTI USING E. COLI 83972 IN SCI PATIENTS
    Richard Hull; Fiscal Year: 2001
    ..there was agreement at a 1992 NIDRR sponsored Consus Validation Conference that ABU in SCI patients with indwelling catheters should be treated only if symptoms occur. Unfortunately, little is known about bacteria associated with ABU...
  29. ANTI-THROMBOGENIC COATING FOR MEDICAL DEVICES
    SCOTT ROSEBROUGH; Fiscal Year: 2003
    ..PROPOSED COMMERCIAL APPLICATIONS: Medical devices and procedures that would benefit from anti- thrombogenic MEDI-COAT/TM system include in dwelling catheters, coronary bypass oxygnators, coronary stents and hemodialysis. ..
  30. CENTRAL REGULATION OF FERTILITY
    REID NORMAN; Fiscal Year: 2000
    ..All of the animals used in these studies will have indwelling catheters which will allow blood sampling and delivery of test substances from a remote site...
  31. ANTI-THROMBOGENIC COATING FOR MEDICAL DEVICES
    SCOTT ROSEBROUGH; Fiscal Year: 2000
    ..APPLICATIONS: Medical devices and procedures that would benefit from anti-thrombogenic MEDI-COAT(TM) system include indwelling catheters, coronary-bypass oxygenators, coronary stents and hemodialysis equipment.
  32. Lipid/DNA/Antigen Complexes for Pseudomonas vaccines
    Jeff Fairman; Fiscal Year: 2004
    ..pneumonia (VAP), severe bums, immunosuppression due to chemotherapy, cystic fibrosis, or patients with indwelling catheters. In these patients, P...
  33. LIGHT, ENVIRONMENTAL ENRICHMENT AND STRESS
    David Lawson; Fiscal Year: 2005
    ..to stressors (prolactin and corticosterone) will be analyzed in the serum of blood samples taken by indwelling catheters and stress related behaviors will be determined by visual observation and standardized behavioral testing...
  34. Novel Therapies for BioFilm-Related Infections
    Timothy Opperman; Fiscal Year: 2005
    ..In the body, infecting bacteria form biofilms on medical implants, such as indwelling catheters. In this biofilm mode of growth, they are resistant to antibiotics and attack by the body's immune system...
  35. HEMOCOMPATIBLE SURFACE TREATMENT
    Bryan Smith; Fiscal Year: 1999
    ..the wide variety of currently available biomedical polymers, including those currently used in vascular grafts, indwelling catheters, implanted prostheses and sensors as well as extracorporeal blood handling equipment.
  36. MethLock vs. heparin as dialysis catheter lock
    Stephen Ash; Fiscal Year: 2008
    ..In Phase II we will implement the protocol in a number of dialysis centers and complete the study as originally proposed or as modified after Phase I. ..
  37. HEMODIALYSIS VASCULAR ACCESS CLINICAL TRIALS CONSORTIUM
    Michael Allon; Fiscal Year: 2007
    ..The primary endpoint will be fistula thrombosis within 6 weeks, and the secondary endpoint will be the ability to use the fistula successfully for dialysis within 6 months. ..
  38. Vascular Access in Hemodialysis Patients
    Michael Allon; Fiscal Year: 2005
    ..The applicant will assist the trainees in acquiring the conceptual skills, research experience, and motivation required to pursue a successful career in Academic Nephrology. ..
  39. Pheresis Treatment of Bioterrorism-Induced Sepsis
    Stephen Ash; Fiscal Year: 2005
    ..The safety systems of the existing PF system will be modified to meet the needs of the stand-alone system. Finally, an animal model of sepsis will be used to check efficacy and safety of the entire system. ..
  40. Infection Risk of Urinary Collection Strategies
    Sanjay Saint; Fiscal Year: 2006
    ..Since approximately 40% of elderly Americans will enter a nursing home at some point, identification of those at risk of infection could have considerable health, quality of life, and economic consequences. ..
  41. RENAL MEDULLARY NITRIC OXIDE AND BLOOD PRESSURE
    David Mattson; Fiscal Year: 2001
    ....
  42. Treatment and/or Prevention of Urinary Tract Infections
    BARBARA TRAUTNER; Fiscal Year: 2008
    ..An agent to prevent and treat UTI that does not encourage microbial resistance would have a significant impact on public health. [unreadable] [unreadable] [unreadable]..
  43. THE CLOUD ADULT
    Robert Sherertz; Fiscal Year: 2003
    ..aureus associated with a viral URI, have been shown to cause outbreaks. Understanding the "cloud phenomenon" may facilitate S.aureus outbreak prevention and possibly the transmission of other pathogens, as well. ..
  44. Clinical Investigation of E.coli Biofilm Formation in the Human Bladder
    BARBARA TRAUTNER; Fiscal Year: 2007
    ..No effective strategy exists to prevent CAUTI in persons who require ongoing catheter use. Identifying genes that are required to cause CAUTI will lead to new strategies to prevent this illness. [unreadable] [unreadable] [unreadable]..
  45. Device use in Nursing Homes: Reducing Risk of Infection
    Lona Mody; Fiscal Year: 2007
    ..abstract_text> ..
  46. E. coli for prevention of Catheter UTI in SCI Patients
    BARBARA TRAUTNER; Fiscal Year: 2006
    ..The overall goal of this project is to develop a new approach for prevention of UTI in persons who rely in indwelling catheters for bladder drainage...
  47. RELATIVE ARGININE DEFICIENCY IN PULMONARY HYPERTENSION
    David Badesch; Fiscal Year: 2004
    ..abstract_text> ..
  48. THERAPY OF HEPATIC METASTASES FROM COLORECTAL CARCINOMA
    Nancy Kemeny; Fiscal Year: 2001
    ..Cryosurgery and newer hepatic arterial therapies are therapeutic modalities that can be used in patients in whom liver resection is impossible. ..
  49. HOME HYGIENE INTERVENTION
    Elaine Larson; Fiscal Year: 2002
    ..Logistic regression, Liang-Zeger regression, and Chi Square analyses will be used to test differences in rates of transmission of symptoms and changes in quantity, types and resistance patterns of microbial flora of the hands. ..
  50. Continuation of Dialysis Access Consortium Clinical Trials
    Jonathan Himmelfarb; Fiscal Year: 2007
    ..The health care cost o maintaining adequate vascular access should also decrease from its current rate of over one billion dollars per year. ..
  51. Type II secretion system of P. aeruginosa in acute lung infection
    Reuben Ramphal; Fiscal Year: 2010
    ..We wish to examine which of the many known toxins are involved in death and to explore new methods to block secretion of the toxins that may eventually be useful for therapy. ..
  52. Molecular Requirements for Recombinant Cytotoxins Efficacy
    Waldemar Debinski; Fiscal Year: 2010
    ..It is expected that the new information gathered will be invaluable in further molecular design of recombinant anti-cancer cytotoxins. ..
  53. ALPHA-1 ADRENERGIC SYSTEM IN ACTIVITY AND DEPRESSION
    Eric A Stone; Fiscal Year: 2010
    ..The research will likely identify the EPI/alpha-1 system as a new and important target for antidepressant and antistress medications ..
  54. Susceptibility Testing, Treatment Choices, and Outcomes of MDR-GNB Infections
    Lisa Maragakis; Fiscal Year: 2009
    ..This research is designed to better understand how providers use information from various microbiology laboratory testing methods to choose treatments and to identify strategies that lead to the best patient outcomes. ..
  55. Medical Maintenance of Hemodialysis Vascular Access (DAC)
    Miguel Vazquez; Fiscal Year: 2006
    ..The health care cost of maintaining adequate vascular access should also decrease from its current rate of over one billion dollars per year. ..
  56. PSEUDOMONAS AERUGINOSA FLAGELLAR BIOGENESIS PATHWAY
    Reuben Ramphal; Fiscal Year: 2007
    ..abstract_text> ..
  57. NABTC Member Intitution Grant (UCSF Project Leader)
    Susan Chang; Fiscal Year: 2008
    ..The overall goal of this program is to more effectively treat patients with primary brain tumors, especially malignant glioma, with the purpose of increasing the duration and quality of survival. ..
  58. Prenatal Hypoxia and Development of Insulin Resistance
    RUSSELL ANTHONY; Fiscal Year: 2006
    ..These studies will provide insight in to the role fetal hypoxia alone may play in the development of Syndrome X. [unreadable] [unreadable]..
  59. Antiproliferative Rx for venous neointimal hyperplasia
    Prabir Roy Chaudhury; Fiscal Year: 2005
    ..We believe that the results from this study could transform the clinical care of hemodialysis patients and at the same time result in the successful clinical application of local therapy for the treatment of neointimal hyperplasia...
  60. Coating Reduces Encrustation on Urethral Stent
    Shih Horng Su; Fiscal Year: 2004
    ..Ureteral stents equipped with the anti-encrustation coating will be compared to many similar products on the market in the aspect of encrustation severity. The data will guide future optimization. ..