imaging phantoms

Summary

Summary: Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)

Top Publications

  1. ncbi Reduction of transient signal oscillations in true-FISP using a linear flip angle series magnetization preparation
    Vibhas S Deshpande
    Department of Radiology, Northwestern University, Chicago, Illinois, USA
    Magn Reson Med 49:151-7. 2003
  2. pmc A method for improving the performance of gradient systems for diffusion-weighted MRI
    Zoltan Nagy
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, UK
    Magn Reson Med 58:763-8. 2007
  3. ncbi Small pulmonary nodules: volumetrically determined growth rates based on CT evaluation
    D F Yankelevitz
    Department of Radiology, New York Presbyterian Hospital Weill Cornell Medical Center, Building Starr 8A23, 525 E 68th St, New York, NY 10021, USA
    Radiology 217:251-6. 2000
  4. ncbi Fiber-optic scanning two-photon fluorescence endoscope
    Mon Thiri Myaing
    Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA
    Opt Lett 31:1076-8. 2006
  5. ncbi Small pulmonary nodules: volume measurement at chest CT--phantom study
    Jane P Ko
    Department of Radiology, Section of Thoracic Imaging, New York University Medical Center, 560 1st Ave, New York, NY 10016, USA
    Radiology 228:864-70. 2003
  6. ncbi Functional MRI with active, fully implanted, deep brain stimulation systems: safety and experimental confounds
    David W Carmichael
    Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, UK
    Neuroimage 37:508-17. 2007
  7. ncbi Parallel magnetic resonance imaging
    David J Larkman
    The Imaging Sciences Department, Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK
    Phys Med Biol 52:R15-55. 2007
  8. ncbi T2 measurement of the human myocardium using a T2-prepared transient-state TrueFISP sequence
    Teng Yi Huang
    Massachusetts General Hospital, MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA
    Magn Reson Med 57:960-6. 2007
  9. pmc Image reconstruction in SNR units: a general method for SNR measurement
    Peter Kellman
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 54:1439-47. 2005
  10. ncbi Partial-volume correction in PET: validation of an iterative postreconstruction method with phantom and patient data
    Boon Keng Teo
    Department of Radiology, University of California, San Francisco, San Francisco, CA 94107, USA
    J Nucl Med 48:802-10. 2007

Detail Information

Publications281 found, 100 shown here

  1. ncbi Reduction of transient signal oscillations in true-FISP using a linear flip angle series magnetization preparation
    Vibhas S Deshpande
    Department of Radiology, Northwestern University, Chicago, Illinois, USA
    Magn Reson Med 49:151-7. 2003
    ..The results demonstrated substantial reduction in the apparent image artifacts when using linearly increasing flip angles during magnetization preparation...
  2. pmc A method for improving the performance of gradient systems for diffusion-weighted MRI
    Zoltan Nagy
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, UK
    Magn Reson Med 58:763-8. 2007
    ..The scaling factor is the square root of the ratio of the expected and observed diffusion constants. In addition, fiber tracking results in the human brain were noticeably affected by improving the gradient system calibration...
  3. ncbi Small pulmonary nodules: volumetrically determined growth rates based on CT evaluation
    D F Yankelevitz
    Department of Radiology, New York Presbyterian Hospital Weill Cornell Medical Center, Building Starr 8A23, 525 E 68th St, New York, NY 10021, USA
    Radiology 217:251-6. 2000
    ..To determine the accuracy of high-resolution computed tomographic (CT) volumetric measurements of small pulmonary nodules to assess growth and malignancy status...
  4. ncbi Fiber-optic scanning two-photon fluorescence endoscope
    Mon Thiri Myaing
    Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA
    Opt Lett 31:1076-8. 2006
    ..Real-time imaging of fluorescent beads and cancer cells has been performed...
  5. ncbi Small pulmonary nodules: volume measurement at chest CT--phantom study
    Jane P Ko
    Department of Radiology, Section of Thoracic Imaging, New York University Medical Center, 560 1st Ave, New York, NY 10016, USA
    Radiology 228:864-70. 2003
    ..Higher precision was associated with use of a PVM with predetermined pure nodule attenuation, high-frequency algorithm, and diagnostic CT technique (120 mAs). A PVM is promising for volume quantification and follow-up of nodules...
  6. ncbi Functional MRI with active, fully implanted, deep brain stimulation systems: safety and experimental confounds
    David W Carmichael
    Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, UK
    Neuroimage 37:508-17. 2007
    ..Further studies are required to determine the safety of MRI with DBS for other MRI systems, transmit coil configurations and DBS arrangements...
  7. ncbi Parallel magnetic resonance imaging
    David J Larkman
    The Imaging Sciences Department, Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK
    Phys Med Biol 52:R15-55. 2007
    ..Finally, active research areas where parallel imaging is being used to improve data quality by repairing artefacted images are also reviewed...
  8. ncbi T2 measurement of the human myocardium using a T2-prepared transient-state TrueFISP sequence
    Teng Yi Huang
    Massachusetts General Hospital, MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA
    Magn Reson Med 57:960-6. 2007
    ..7% with signal averaging (NEX = 10). According to our preliminary results, the T2-TrueFISP method is expected to provide a robust and sensitive tool for clinical application of myocardial BOLD contrast imaging...
  9. pmc Image reconstruction in SNR units: a general method for SNR measurement
    Peter Kellman
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 54:1439-47. 2005
    ..The procedure includes scaling for noise equivalent bandwidth of digital receivers, FFTs and associated window functions (raw data filters), and array combining...
  10. ncbi Partial-volume correction in PET: validation of an iterative postreconstruction method with phantom and patient data
    Boon Keng Teo
    Department of Radiology, University of California, San Francisco, San Francisco, CA 94107, USA
    J Nucl Med 48:802-10. 2007
    ..An iterative postreconstruction method was evaluated that corrects for PVEs without a priori knowledge of tumor size or background...
  11. ncbi Flat panel detector-based volumetric CT: prototype evaluation with volumetry of small artificial nodules in a pulmonary phantom
    Katharina Marten
    Department of Radiology, Klinikum rechts der Isar, Technical University, Munich, Germany
    J Thorac Imaging 19:156-63. 2004
    ..To evaluate amorphous silicone-based flat panel detector volumetric CT (VCT) in volumetric assessment of small nodules in a pulmonary phantom, and to perform comparative experiments with 4-row multislice CT (MSCT)...
  12. ncbi Test liquids for quantitative MRI measurements of self-diffusion coefficient in vivo
    P S Tofts
    Department of Clinical Neurology, Institute of Neurology, University College London, UK
    Magn Reson Med 43:368-74. 2000
    ..5 T and proton density are given. n-tridecane has a diffusion coefficient close to that of normal white matter. The longer n-alkanes may be useful T2 standards. Measurements from a spin-echo MRI sequence agreed to within 2%...
  13. ncbi Can PET provide the 3D extent of tumor motion for individualized internal target volumes? A phantom study of the limitations of CT and the promise of PET
    Curtis B Caldwell
    Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 55:1381-93. 2003
    ....
  14. pmc Semi-automatic measurement of the airway dimension by computed tomography using the full-width-half-maximum method: a study on the measurement accuracy according to the CT parameters and size of the airway
    Namkug Kim
    Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Korean J Radiol 9:226-35. 2008
    ..To assess the influence of variable factors such as the size of the airway and the CT imaging parameters such as the reconstruction kernel, field-of-view (FOV), and slice thickness on the automatic measurement of airway dimension...
  15. ncbi Effect of varying CT section width on volumetric measurement of lung tumors and application of compensatory equations
    Helen T Winer-Muram
    Department of Radiology, Indiana University School of Medicine, Indianapolis, IN, USA
    Radiology 229:184-94. 2003
    ..To determine how volume measurements of simulated and clinical lung tumors at standard computed tomographic (CT) lung window and level settings vary with section width and to derive and apply compensatory equations...
  16. ncbi Residual motion of lung tumours in gated radiotherapy with external respiratory surrogates
    Ross I Berbeco
    Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Phys Med Biol 50:3655-67. 2005
    ..Treatment margins that account for motion should be individualized and daily imaging should be performed to ensure that the residual motion is not exceeding the planned motion on a given day...
  17. ncbi Synchronized moving aperture radiation therapy (SMART): improvement of breathing pattern reproducibility using respiratory coaching
    Toni Neicu
    Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
    Phys Med Biol 51:617-36. 2006
    ..However, about half of the patients could not follow both audio and video instructions simultaneously, suggesting that the current coaching technique requires improvements...
  18. ncbi Intrathoracic tumour motion estimation from CT imaging using the 3D optical flow method
    Thomas Guerrero
    Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Phys Med Biol 49:4147-61. 2004
    ..Surprisingly, oesophageal tumour motion was large and nonuniform, with greatest motion occurring at the gastro-oesophageal junction...
  19. ncbi Practical approaches to the evaluation of signal-to-noise ratio performance with parallel imaging: application with cardiac imaging and a 32-channel cardiac coil
    Scott B Reeder
    Department of Clinical Radiology, University Hospitals Grosshadern, Ludwig Maximilians University, Munich, Germany
    Magn Reson Med 54:748-54. 2005
    ..With this acceleration, a cardiac function study consisting of 6 image planes (3 short-axis views, 3 long-axis views) was obtained in an 18-heartbeat breath-hold...
  20. ncbi 4D-CT imaging of a volume influenced by respiratory motion on multi-slice CT
    Tinsu Pan
    GE Medical Systems, Waukesha, Wisconsin, USA
    Med Phys 31:333-40. 2004
    ..We have applied the scanning and registration methods on phantom, animal and patients, and initial results suggest the applicability of both the scanning and the registration methods...
  21. ncbi Improved lumen visualization in metallic vascular implants by reducing RF artifacts
    Lambertus W Bartels
    Image Sciences Institute, Department of Radiology, University Medical Center Utrecht, The Netherlands
    Magn Reson Med 47:171-80. 2002
    ..The method was tested in vitro and in vivo in a pig model and allowed adequate depiction of the interior of a nitinol stent and that of a vena cava filter in contrast-enhanced MR angiograms. Magn Reson Med 47:171-180, 2002...
  22. ncbi Accuracy of automated volumetry of pulmonary nodules across different multislice CT scanners
    Marco Das
    Department of Diagnostic Radiology, RWTH Aachen University, Pauwelsstrasse 30, 52072 Aachen, Germany
    Eur Radiol 17:1979-84. 2007
    ..Nodule volumetry is accurate with a reasonable volume error in data from different scanner vendors. This may have an important impact for intraindividual follow-up studies...
  23. ncbi Artifacts in computed tomography scanning of moving objects
    George T Y Chen
    Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    Semin Radiat Oncol 14:19-26. 2004
    ..These simulations predict that the effect is clearly observable even if the amplitude is decreased to 0.5 cm. Implications of scanning moving objects on treatment planning are discussed...
  24. pmc Optimization of extracranial stereotactic radiation therapy of small lung lesions using accurate dose calculation algorithms
    Barbara Dobler
    Department of Radiation Oncology, Mannheim Medical Center, University of Heidelberg, Mannheim, Germany
    Radiat Oncol 1:45. 2006
    ..The aim of this study was to compare and to validate different dose calculation algorithms for the use in radiation therapy of small lung lesions and to optimize the treatment planning using accurate dose calculation algorithms...
  25. pmc Phase-sensitive inversion recovery for detecting myocardial infarction using gadolinium-delayed hyperenhancement
    Peter Kellman
    Laboratory of Cardiac Energetics, National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 47:372-83. 2002
    ..Phase-sensitive detection also has the advantage of decreasing the sensitivity to changes in tissue T(1) with increasing delay from contrast agent injection...
  26. ncbi In vitro validation of phase-contrast flow measurements at 3 T in comparison to 1.5 T: precision, accuracy, and signal-to-noise ratios
    Joachim Lotz
    Department of Diagnostic Radiology, Hannover Medical School, 30625 Hannover, Germany
    J Magn Reson Imaging 21:604-10. 2005
    ..To evaluate the signal-to-noise ratio (SNR), precision, and accuracy of phase-contrast flow measurements at 3 T with the help of an in vitro model and to compare the results with data from two 1.5-T scanners...
  27. ncbi Speckle tracking ultrasound is independent of insonation angle and gain: an in vitro investigation of agreement with sonomicrometry
    Kim Sivesgaard
    Department of Anaesthesia and Intensive Care, Aarhus University Hospital, Skejby, Aarhus, Denmark
    J Am Soc Echocardiogr 22:852-8. 2009
    ..The aim of this study was to investigate the influence of different angles of insonation with a range of scanner settings...
  28. ncbi Normal organ volume assessment from abdominal CT
    E M Geraghty
    Department of Radiology, University of California, Davis, Medical Center, Research Imaging Center, 4701 X Street, Sacramento, CA 95817, USA
    Abdom Imaging 29:482-90. 2004
    ..Normative data are provided to allow physicians to estimate where in the normal range a particular organ volume lays. Organ volumes may be useful as quantitative indices of pathologic conditions...
  29. ncbi Cyclic variation of T1 in the myocardium at 3 T
    Janaka Wansapura
    Cincinnati Children s Hospital Medical Center, Imaging Research Center, Cincinnati, OH 45229, USA
    Magn Reson Imaging 24:889-93. 2006
    ..With further improvements, this technique could be used to assess the myocardial blood volume changes during the cardiac cycle...
  30. ncbi Comparison of two digital radiostereometric analysis methods in the determination of femoral head penetration in a total hip replacement phantom
    Charles R Bragdon
    Orthopaedic Biomechanics and Biomaterials Laboratory, Adult Reconstructive Unit, Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, 1126 Fruit Street, Jackson Building, Boston, MA 02114, USA
    J Orthop Res 22:659-64. 2004
    ..The results using the two marker configurations were similar...
  31. ncbi Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance
    Timothy G St Pierre
    School of Physics, University of Western Australia, Perth, Australia
    Blood 105:855-61. 2005
    ..Measurements of proton transverse relaxivity of aqueous MnCl2 phantoms on 13 different magnetic resonance imaging units using the method yielded a coefficient of variation of 2.1%...
  32. ncbi 64-slice multidetector coronary CT angiography: in vitro evaluation of 68 different stents
    David Maintz
    Department of Clinical Radiology, University of Muenster, Germany
    Eur Radiol 16:818-26. 2006
    ..Using 64-slice CT and high-resolution kernel, the majority of stent products show a lumen visibility of more than 50% of the stent diameter...
  33. ncbi Single-voxel proton MRS of the human brain at 1.5T and 3.0T
    P B Barker
    Department of Neurology, Henry Ford Hospital, Detroit, Michigan, USA
    Magn Reson Med 45:765-9. 2001
    ..Spectra in phantoms demonstrated significantly improved resolution at 3T compared to 1.5T, but resolution improvements in in vivo spectra were almost completely offset by increased linewidths at higher field...
  34. ncbi Fast high-resolution T1 mapping of the human brain
    Ralf Deichmann
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, London, UK
    Magn Reson Med 54:20-7. 2005
    ..In addition, an improved fitting algorithm based on smoothed flip angle maps is presented and tested successfully...
  35. ncbi First performance evaluation of a dual-source CT (DSCT) system
    Thomas G Flohr
    Siemens Medical Solutions, Computed Tomography CTE PA, Siemensstr 1, 91301, Forchheim, Germany
    Eur Radiol 16:256-68. 2006
    ..As a potential application of the dual-energy acquisition mode, the automatic separation of bones and iodine-filled vessels is demonstrated...
  36. ncbi Full-brain T1 mapping through inversion recovery fast spin echo imaging with time-efficient slice ordering
    David C Zhu
    Department of Radiology, University of Chicago, Chicago, Illinois 60637, USA
    Magn Reson Med 54:725-31. 2005
    ..To reduce the scan time and maintain the quality of the T1 maps, we propose a new full-brain T1 mapping pulse sequence based on a multislice inversion recovery fast spin echo imaging using a time-efficient slice ordering technique...
  37. ncbi Variability in RF-induced heating of a deep brain stimulation implant across MR systems
    Kenneth B Baker
    Center for Neurological Restoration, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Magn Reson Imaging 24:1236-42. 2006
    ..To compare the MRI-related heating per unit of specific absorption rate (SAR) profile of a conductive implant between two 1.5-Tesla/64 MHz MR systems using a transmit/receive (t/r) head coil configuration...
  38. ncbi Radiation dose and image quality in pediatric CT: effect of technical factors and phantom size and shape
    Marilyn J Siegel
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Blvd, St Louis, MO 63110, USA
    Radiology 233:515-22. 2004
    ..To evaluate effects of varying tube current and voltage on radiation dose, image noise, and image contrast with different phantom sizes and shapes...
  39. ncbi Dosimetric feasibility of cone-beam CT-based treatment planning compared to CT-based treatment planning
    Sua Yoo
    Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
    Int J Radiat Oncol Biol Phys 66:1553-61. 2006
    ..However, it is yet unknown whether CBCT could be used in dose calculation for replanning in adaptive radiation therapy. This study investigates the dosimetric feasibility of CBCT-based treatment planning...
  40. ncbi Airflow limitation and airway dimensions in chronic obstructive pulmonary disease
    Masaru Hasegawa
    First Department of Medicine, Hokkaido University School of Medicine, N 15 W 7 Kita ku, Sapporo 060 8638, Japan
    Am J Respir Crit Care Med 173:1309-15. 2006
    ..Computed tomography has been widely used to assess emphysema severity, but less attention has been paid to the assessment of airway disease using computed tomography...
  41. ncbi Performance evaluation of a multi-slice CT system with 16-slice detector and increased gantry rotation speed for isotropic submillimeter imaging of the heart
    Thomas Flohr
    Siemens Medical Solutions, Computed Tomography, Forchheim, Germany
    Herz 28:7-19. 2003
    ..We evaluate advances in ECG-gated scanning of the heart and the coronary arteries with recently introduced 16-slice CT equipment (SOMATOM Sensation 16, Siemens, Forchheim, Germany)...
  42. ncbi EGSNRC Monte Carlo study of the effect of photon energy and field margin in phantoms simulating small lung lesions
    E K Osei
    Princess Margaret Hospital, Department of Radiation Physics, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada
    Med Phys 30:2706-14. 2003
    ..The effect, which is predominant in determining the target dose, depends on the beam energy, target-field edge distance, lung density, and the depth and size of the target...
  43. ncbi Patient-circumference-adapted dose regulation in body computed tomography. A practical and flexible formula
    U Nyman
    Department of Diagnostic Radiology, Lasarettet Trelleborg, Sweden
    Acta Radiol 46:396-406. 2005
    ..To illustrate that the attenuation formula based on monochromatic radiation in homogeneous objects may be used for dose regulation in body computed tomography (CT) based on patient circumference and using a simple cloth measuring tape...
  44. ncbi An experimental investigation on intra-fractional organ motion effects in lung IMRT treatments
    Steve B Jiang
    Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Phys Med Biol 48:1773-84. 2003
    ..From the two IMRT cases we studied where tumour motion is perpendicular to MLC leaf motion, the dose variation was found to be insensitive to the MLC delivery mode...
  45. ncbi Suitability of the Cordis Stabilizer marker guide wire for quantitative coronary angiography calibration: an in vitro and in vivo study
    G Koning
    Department of Radiology, Leiden University Medical Center, Leiden, Netherlands
    Catheter Cardiovasc Interv 52:334-41. 2001
    ..In conclusion, if accurate assessment of the lesion length is important, the marker wire should be used for calibration purposes. For vessel diameter measurements, the conventional catheter calibration approach is the method of choice...
  46. ncbi Effects of noise, image resolution, and ROI definition on the accuracy of standard uptake values: a simulation study
    Ronald Boellaard
    PET Center, VU University Medical Center, Amsterdam, The Netherlands
    J Nucl Med 45:1519-27. 2004
    ..Therefore, an experimental and simulation study was performed to determine the effects of noise, image resolution, and region-of-interest (ROI) definition on the accuracy of SUVs...
  47. ncbi Reduction of eddy-current-induced distortion in diffusion MRI using a twice-refocused spin echo
    T G Reese
    Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Magn Reson Med 49:177-82. 2003
    ..This new sequence is demonstrated in phantom measurements and in diffusion anisotropy images of normal human brain...
  48. ncbi Renal cyst pseudoenhancement with beam hardening effect on CT attenuation
    Takehiko Gokan
    Department of Radiology, Showa University School of Medicine, Tokyo, Japan
    Radiat Med 20:187-90. 2002
    ..The purpose of this study was to evaluate the extent of pseudoenhancement in a phantom model using three different CT scanners...
  49. ncbi Baseline correction of phase contrast images improves quantification of blood flow in the great vessels
    Alexander Chernobelsky
    Cardiovascular Research Foundation, New York, New York, USA
    J Cardiovasc Magn Reson 9:681-5. 2007
    ..The purpose of this study was to assess the magnitude of these flow errors and to validate a clinically applicable method for their correction...
  50. ncbi Measurement of myocardial frequency offsets during first pass of a gadolinium-based contrast agent in perfusion studies
    Pedro Ferreira
    National Heart and Lung Institute, Imperial College, London, UK
    Magn Reson Med 60:860-70. 2008
    ..However, when added to other sources of off-resonance it can cause dark rims in particular regions of the myocardium wall in balanced-SSFP sequences...
  51. ncbi Three-dimensional magnetic resonance myocardial motion tracking from a single image plane
    Khaled Z Abd-Elmoniem
    Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland, USA
    Magn Reson Med 58:92-102. 2007
    ..This capability should open up new avenues for the automatic quantification of cardiac motion and strain for scientific and clinical purposes...
  52. pmc Acoustomotive optical coherence elastography for measuring material mechanical properties
    Xing Liang
    Department of Electrical and Computer Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana Champaign, 405 North Mathews, Urbana, Illinois 61801, USA
    Opt Lett 34:2894-6. 2009
    ..Quantitative measurement, microscale resolution, and remote excitation are the main features of AM-OCE, which make the technique promising for measuring biomechanical properties...
  53. ncbi Comparison of dose calculation algorithms in slab phantoms with cortical bone equivalent heterogeneities
    P Carrasco
    Servei de Radiofísica i Radioprotecció, Hospital de la Santa Creu i Sant Pau, St Antoni Maria Claret 167, 08025 Barcelona, Spain
    Med Phys 34:3323-33. 2007
    ....
  54. ncbi Audio frequency in vivo optical coherence elastography
    Steven G Adie
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, The University of Western Australia, Crawley, Western Australia, Australia
    Phys Med Biol 54:3129-39. 2009
    ..We present quantitative results of sub-micron excitation at 820 Hz in a layered phantom and the first such measurements in human skin in vivo...
  55. ncbi ACUT2E TSE-SSFP: a hybrid method for T2-weighted imaging of edema in the heart
    Anthony H Aletras
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health DHHS, 10 Center Drive, Bethesda, MD 20892, USA
    Magn Reson Med 59:229-35. 2008
    ..Imperfect blood suppression, present in all animals on some TSE images, was a problem eliminated by TSE-SSFP and T2-prepared SSFP...
  56. ncbi Initial in vivo studies with a polymer-based MR-compatible guide wire
    Ralf Mekle
    Division of MR Physics, Department of Medical Radiology, University Hospital Basel, Basel, Switzerland
    J Vasc Interv Radiol 20:1384-9. 2009
    ..Results show great potential for this guide wire in aiding the realization of interventional peripheral MR angiography in humans...
  57. ncbi In vivo dynamic optical coherence elastography using a ring actuator
    Brendan F Kennedy
    School of Electrical, Electronic and Computer Engineering, The University of Western Australia, Crawley, Western Australia, Australia
    Opt Express 17:21762-72. 2009
    ..The results constitute the first demonstration of a practical means of performing in vivo dynamic optical coherence elastography on a human subject...
  58. pmc A robust Monte Carlo model for the extraction of biological absorption and scattering in vivo
    Janelle E Bender
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    IEEE Trans Biomed Eng 56:960-8. 2009
    ..We found the best reference-target phantom combinations to be ones with similar scattering levels. The results from these phantom studies provide a set of guidelines for extracting optical parameters from clinical studies...
  59. ncbi Flow measurement by magnetic resonance: a unique asset worth optimising
    Philip J Kilner
    CMR Unit, Royal Brompton Hospital, Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, Sydney Street, London, UK
    J Cardiovasc Magn Reson 9:723-8. 2007
    ..Awareness of the potential problems and concerted efforts towards optimisation are needed from manufacturers and users to make appropriate use of phase contrast flow measurement - a unique strength of cardiovascular magnetic resonance...
  60. ncbi Retrospective IMRT dose reconstruction based on cone-beam CT and MLC log-file
    Louis Lee
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 5847, USA
    Int J Radiat Oncol Biol Phys 70:634-44. 2008
    ..The aim of this work is to reconstruct the intensity-modulated radiation therapy dose delivered to an HN patient using the CBCT and multileaf collimator (MLC) log-files...
  61. ncbi 3D myocardial tissue tracking with slice followed cine DENSE MRI
    Bruce S Spottiswoode
    UCT MRC Medical Imaging Research Unit, University of Cape Town, South Africa
    J Magn Reson Imaging 27:1019-27. 2008
    ..To track three-dimensional (3D) myocardial tissue motion using slice followed cine displacement encoded imaging with stimulated echoes (DENSE)...
  62. ncbi A novel high-sensitivity rapid-acquisition single-photon cardiac imaging camera
    Sanjiv S Gambhir
    Departments of Radiology and Bioengineering, Molecular Imaging Program, Stanford University, Stanford, California, USA
    J Nucl Med 50:635-43. 2009
    ..The compact new camera uses a unique method for localizing gamma-photon information with a bank of 9 solid-state detector columns with tungsten collimators that rotate independently...
  63. pmc Optical micro-scale mapping of dynamic biomechanical tissue properties
    Xing Liang
    Department of Electrical and Computer Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Opt Express 16:11052-65. 2008
    ..08%. Spatial micro-scale mapping of elastic moduli of tissue offers the potential for basic science and clinical investigations into the role biomechanics play in health and disease...
  64. ncbi Correction of heart motion due to respiration in clinical myocardial perfusion SPECT scans using respiratory gating
    Gil Kovalski
    Faculty of Biomedical Engineering, Technion, Israel Institute of Technology, Haifa, Israel
    J Nucl Med 48:630-6. 2007
    ..Several studies have described nonuniform blurring of myocardial perfusion imaging (MPI) due to respiration. This article describes a technique for correcting the respiration effect and assesses its effectiveness in clinical studies...
  65. ncbi Gadolinium-enhanced off-resonance contrast angiography
    Robert R Edelman
    Department of Radiology, Evanston Northwestern Healthcare and Northwestern University School of Medicine, Evanston, Illinois 60201, USA
    Magn Reson Med 57:475-84. 2007
    ..Further study is needed to determine the practicality and potential clinical utility of this method...
  66. ncbi Organ and effective doses in pediatric patients undergoing helical multislice computed tomography examination
    Choonik Lee
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    Med Phys 34:1858-73. 2007
    ....
  67. pmc A new approach to the assessment of lumen visibility of coronary artery stent at various heart rates using 64-slice MDCT
    J M Groen
    Department of Radiology, University Medical Center Groningen, University of Groningen, The Netherlands
    Eur Radiol 17:1879-84. 2007
    ..Cardiac movement during data acquisition causes approximately twice as much blurring compared with the influence of temporal resolution on image quality...
  68. ncbi Threshold adjusted calcium scoring using CT is less susceptible to cardiac motion and more accurate
    J M Groen
    Department of Radiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands
    Med Phys 36:438-46. 2009
    ..Calcium scoring using an adjusted threshold is less susceptible to cardiac motion and more accurate compared to the physical values...
  69. pmc Novel solid-state-detector dedicated cardiac camera for fast myocardial perfusion imaging: multicenter comparison with standard dual detector cameras
    Fabio P Esteves
    Department of Radiology, Emory University School of Medicine, Atlanta, GA 30322, USA
    J Nucl Cardiol 16:927-34. 2009
    ..The primary goal was a per-patient analysis of diagnostic performance of the DNM using S-SPECT as the reference standard...
  70. ncbi Interleaved T(1) and T(2) relaxation time mapping for cardiac applications
    Ulrike Blume
    King s College London, UK
    J Magn Reson Imaging 29:480-7. 2009
    ..The calculation of both T(1) and T(2) maps can be relevant for quantitative diagnosis. In this work, we present a simultaneous quantification of T(1)-T(2) relaxation times of a short-axis view of the heart in a single scan...
  71. ncbi Tumor tracking and motion compensation with an adaptive tumor tracking system (ATTS): system description and prototype testing
    Jürgen Wilbert
    Department of Radiation Oncology, University of Wurzburg, Josef Schneider Strasse II, 97080 Wurzburg, Germany
    Med Phys 35:3911-21. 2008
    ..In conclusion, this study demonstrated that it is technically feasible to compensate breathing induced tumor motion in the lung with the adaptive tumor tracking system...
  72. ncbi Ultrasound elastography: a dynamic programming approach
    Hassan Rivaz
    Engineering Research Center for Computer Integrated Surgery, Johns Hopkins University, 3400 N Charles Street, Baltimore, MD 21218, USA
    IEEE Trans Med Imaging 27:1373-7. 2008
    ..The method operates in less than 1 s and is thus also potentially suitable for real time elastography...
  73. ncbi Novel method for rapid, simultaneous T1, T*2, and proton density quantification
    J B M Warntjes
    Center for Medical Image Science and Visualization, Linkoping University, Linkoping, Sweden
    Magn Reson Med 57:528-37. 2007
    ..We validated the experimental results against existing methods, and provide a clinical example in which quantification of the whole brain using 1.5 mm(3) voxels was achieved in less than 8 min...
  74. ncbi Temperature and SAR measurement errors in the evaluation of metallic linear structures heating during MRI using fluoroptic probes
    E Mattei
    Department of Technologies and Health, Italian National Institute of Health, Roma, Italy
    Phys Med Biol 52:1633-46. 2007
    ..MRI heating evaluations with temperature probes should use a contact position minimizing the maximum error, need to be accompanied by a thorough uncertainty budget and the temperature and SAR errors should be specified...
  75. ncbi Evaluation of 3D Monte Carlo-based scatter correction for 201Tl cardiac perfusion SPECT
    Jianbin Xiao
    Department of Nuclear Medicine, Image Sciences Institute, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Nucl Med 48:637-44. 2007
    ..Monte Carlo simulation is a general and accurate method well suited to modeling this scatter...
  76. ncbi Clinical results of a novel wide beam reconstruction method for shortening scan time of Tc-99m cardiac SPECT perfusion studies
    Salvador Borges-Neto
    Department of Radiology, Division of Nuclear Medicine, Duke University Medical Center, Durham, NC 27710, USA
    J Nucl Cardiol 14:555-65. 2007
    ....
  77. ncbi Comparing the accuracy of four-dimensional photon dose calculations with three-dimensional calculations using moving and deforming phantoms
    Yevgeniy Y Vinogradskiy
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Med Phys 36:5000-6. 2009
    ..The purpose of this work was to quantify the increase in accuracy of 4D dose calculations versus 3D dose calculations...
  78. pmc Radiation dose reduction at a price: the effectiveness of a male gonadal shield during helical CT scans
    Lawrence T Dauer
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    BMC Med Imaging 7:5. 2007
    ..This information is obtained to assist the attending radiologist in the decision to utilize such male gonadal shields in pediatric imaging practice...
  79. ncbi Imaging doses from the Elekta Synergy X-ray cone beam CT system
    A Amer
    North Western Medical Physics, Christie Hospital NHS Trust, Manchester M20 4BX, UK
    Br J Radiol 80:476-82. 2007
    ..It is important to consider further development of low dose CBCT techniques to keep additional doses as low as reasonably practicable...
  80. ncbi MR heating tests of MR critical implants
    Wolfgang Kainz
    J Magn Reson Imaging 26:450-1. 2007
  81. ncbi Online planning and delivery technique for radiotherapy of spinal metastases using cone-beam CT: image quality and system performance
    Daniel Letourneau
    Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 67:1229-37. 2007
    ..The technical challenges of this approach include cone-beam CT (CBCT) image quality for target definition, online planning, and efficient process integration...
  82. ncbi Positioning accuracy of cone-beam computed tomography in combination with a HexaPOD robot treatment table
    Jürgen Meyer
    Department of Physics and Astronomy, University of Canterbury, Christchurch, New Zealand
    Int J Radiat Oncol Biol Phys 67:1220-8. 2007
    ..To scrutinize the positioning accuracy and reproducibility of a commercial hexapod robot treatment table (HRTT) in combination with a commercial cone-beam computed tomography system for image-guided radiotherapy (IGRT)...
  83. ncbi Dose calculation using megavoltage cone-beam CT
    Olivier Morin
    Comprehensive Cancer Center, Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA 94143, USA
    Int J Radiat Oncol Biol Phys 67:1201-10. 2007
    ..To demonstrate the feasibility of performing dose calculation on megavoltage cone-beam CT (MVCBCT) of head-and-neck patients in order to track the dosimetric errors produced by anatomic changes...
  84. ncbi Coronary artery calcium: a multi-institutional, multimanufacturer international standard for quantification at cardiac CT
    Cynthia H McCollough
    Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Radiology 243:527-38. 2007
    ..To develop a consensus standard for quantification of coronary artery calcium (CAC)...
  85. ncbi Optimization and validation of a fully-integrated pulse sequence for modified look-locker inversion-recovery (MOLLI) T1 mapping of the heart
    Daniel R Messroghli
    Cardiac MRI Unit, Franz Volhard Klinik, Charite Campus Buch, Universitatsmedizin Berlin, HELIOS Klinikum Berlin, Germany
    J Magn Reson Imaging 26:1081-6. 2007
    ..To optimize and validate a fully-integrated version of modified Look-Locker inversion-recovery (MOLLI) for clinical single-breathhold cardiac T1 mapping...
  86. ncbi An approach to MRI-based dosimetry for transcranial magnetic stimulation
    Luis Hernandez-Garcia
    Functional MRI Laboratory, Ann Arbor, MI 48109 2108, USA
    Neuroimage 36:1171-8. 2007
    ..The measured static field can then be scaled to calculate the effects of a dynamic TMS pulse. This article includes a study demonstrating the feasibility of this approach on a phantom and a human subject...
  87. pmc A 128-channel receive-only cardiac coil for highly accelerated cardiac MRI at 3 Tesla
    Melanie Schmitt
    Department of Radiology, A A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    Magn Reson Med 59:1431-9. 2008
    ..The ability of the 128-channel coil to facilitate highly accelerated cardiac imaging was demonstrated in four volunteers using acceleration factors up to seven-fold (R=7) in a single spatial dimension...
  88. ncbi Feasibility of real-time magnetic resonance-guided angioplasty and stenting of renal arteries in vitro and in Swine, using a new polyetheretherketone-based magnetic resonance-compatible guidewire
    Sebastian Kos
    Division of Interventional Radiology, Institute of Radiology, University Hospital Basel, Basel, Switzerland
    Invest Radiol 44:234-41. 2009
    ..Demonstrate the usability of a new polyetheretherketone (PEEK)-based MR-compatible guidewire for renal artery catheterization, angioplasty, and stenting under MR-guidance using MR-visible markers, in vitro and in vivo...
  89. ncbi Dual-source computed tomography for assessing cardiac function: a phantom study
    Andreas H Mahnken
    Department of Diagnostic Radiology, University Hospital, RWTH Aachen University, Aachen, Germany
    Invest Radiol 42:491-8. 2007
    ..To investigate the influence of heart rate and temporal resolution on the assessment of global ventricular function with dual-source computed tomography (DSCT)...
  90. ncbi Tracking planar orientations of active MRI needles
    Shashank Sathyanarayana
    Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland, USA
    J Magn Reson Imaging 26:386-91. 2007
    ..To determine and track the planar orientation of active interventional devices without using localizing RF microcoils...
  91. ncbi Validation of metal oxide semiconductor field effect transistor technology for organ dose assessment during CT: comparison with thermoluminescent dosimetry
    Terry T Yoshizumi
    Department of Radiology, Duke University Medical Center, Box 3155, Durham, NC 27710, USA
    AJR Am J Roentgenol 188:1332-6. 2007
    ....
  92. ncbi Comparative evaluation of organ and effective doses for paediatric patients with those for adults in chest and abdominal CT examinations
    K Fujii
    Graduate School of Medicine, Nagoya University, Daikominami, Higashi ku, Nagoya, Japan
    Br J Radiol 80:657-67. 2007
    ....
  93. ncbi Development of a frameless stereotactic radiosurgery system based on real-time 6D position monitoring and adaptive head motion compensation
    Rodney D Wiersma
    Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL 60637, USA
    Phys Med Biol 55:389-401. 2010
    ..5 mm tolerance 86% of the time and the 1.0 mm tolerance 45% of the time without motion correction. With correction, this percentage was reduced to 5% and 2% for the 0.5 mm and 1.0 mm tolerances, respectively...
  94. ncbi Experimental verification of a commercial Monte Carlo-based dose calculation module for high-energy photon beams
    Thomas Künzler
    Division of Medical Radiation Physics, Department of Radiotherapy, Medical University Vienna AKH Wien, Vienna, Austria
    Phys Med Biol 54:7363-77. 2009
    ..7% +/- 3.7%, the average gamma(1%) value was 1.19 +/- 0.16 and the mean 2D gamma-value was 0.44 +/- 0.07 in the heterogeneous phantom. The iPlan MC algorithm leads to accurate dosimetric results under clinical test conditions...
  95. ncbi Variability of repeated coronary artery calcium scoring and radiation Dose on 64- and 16-slice computed tomography by prospective electrocardiographically-triggered axial and retrospective electrocardiographically-gated spiral computed tomography: a phant
    Jun Horiguchi
    Department of Clinical Radiology, Hiroshima University Hospital, Hiroshima, 734 8551, Japan
    Acad Radiol 15:958-65. 2008
    ....
  96. ncbi Comparison of the effectiveness of saturation pulses in the heart at 3T
    Daniel Kim
    Department of Radiology, New York University, New York, New York 10016, USA
    Magn Reson Med 59:209-15. 2008
    ..001), but not different between the pulse train and BIR-4 pulses. The performances of all three saturation pulses were comparatively poorer in the right ventricle (RV) than in the LV, respectively...
  97. pmc Review of failed CT phantom image evaluations in 2005 and 2006 by the CT accreditation program of the Korean Institute for Accreditation of Medical Image
    Hye Jung Park
    Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Korea
    Korean J Radiol 9:354-63. 2008
    ..We reviewed all the failed CT phantom image evaluations performed in 2005 and 2006...
  98. pmc Labeling efficacy of superparamagnetic iron oxide nanoparticles to human neural stem cells: comparison of ferumoxides, monocrystalline iron oxide, cross-linked iron oxide (CLIO)-NH2 and tat-CLIO
    Miyeoun Song
    Department of Neurology, Clinical Research Institute, Seoul National University Hospital, Seoul National University, Seoul, Korea
    Korean J Radiol 8:365-71. 2007
    ....
  99. ncbi 64 slice MDCT generally underestimates coronary calcium scores as compared to EBT: a phantom study
    M J W Greuter
    Department of Radiology, University Medical Center Groningen, University of Groningen, Groningen The Netherlands
    Med Phys 34:3510-9. 2007
    ..System information and scanprotocol is therefore needed for every calcium score procedure to ensure a correct clinical interpretation of the obtained calcium score results...
  100. ncbi Evaluation of image-guided positioning for frameless intracranial radiosurgery
    Michael Lamba
    Department of Radiation Oncology, Brain Tumor Center, University of Cincinnati Neuroscience Institute, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0757, USA
    Int J Radiat Oncol Biol Phys 74:913-9. 2009
    ..Recent improvements in image-guidance systems have introduced the possibility of image-guided radiosurgery with nonrigid immobilization. We present data on the alignment accuracy and patient stability of a frameless image-guided system...
  101. ncbi Sparse MRI: The application of compressed sensing for rapid MR imaging
    Michael Lustig
    Magnetic Resonance Systems Research Laboratory, Department of Electrical Engineering, Stanford University, Stanford, California 94305 9510, USA
    Magn Reson Med 58:1182-95. 2007
    ..Examples demonstrate improved spatial resolution and accelerated acquisition for multislice fast spin-echo brain imaging and 3D contrast enhanced angiography...

Research Grants78

  1. Multimodal Retinal Functional Imaging for Diabetic Retinopathy
    Hao F Zhang; Fiscal Year: 2013
    ..Validate and optimize the integrated system by imaging phantoms and the eyes of normal rats and rabbits. Aim 4...
  2. Advanced IVUS Imaging with MUTs
    FAHRETTIN L DEGERTEKIN; Fiscal Year: 2010
    ..propose to implement a prototype side looking CMUT-IVUS catheter with annular arrays, and use it on relevant imaging phantoms for validation...
  3. RESOLUTION LIMITS FOR FLUORESCENCE TOMOGRAPHIC MOLECULAR IMAGING
    XIAOFENG STEVE ZHANG; Fiscal Year: 2012
    ..software package for FDOT simulations and image reconstruction;(ii) Determine FDOT resolution limits in imaging phantoms;and (iii) Determine the resolution limits with prior anatomical information and apply the technology to lung ..
  4. RESOLUTION LIMITS FOR FLUORESCENCE TOMOGRAPHIC MOLECULAR IMAGING
    XIAOFENG STEVE ZHANG; Fiscal Year: 2011
    ..software package for FDOT simulations and image reconstruction;(ii) Determine FDOT resolution limits in imaging phantoms;and (iii) Determine the resolution limits with prior anatomical information and apply the technology to lung ..
  5. Intra-operative specimen tomosynthesis for margin assessment in breast surgery
    EMRE TOKER; Fiscal Year: 2009
    ..in a pre-clinical setting, utilizing simulated excised breast tissue samples and standard breast x-ray imaging phantoms. In Phase I of this research, we will utilize both computer-simulated and physical phantoms to quantify the ..
  6. ENHANCED CALIBRATION PHANTOM FOR ULTRASONIC IMAGING
    ROBERT NAUM; Fiscal Year: 1999
    ..the accuracy of medical ultrasound imaging and provide both technical and quality assurance advantages to health care providers, medical centers and research scientist PROPOSED COMMERCIAL APPLICATIONS: None provided ..
  7. New Multi-Channel ASIC and Si Detector for Gamma Cameras
    CAROLYN TULL; Fiscal Year: 2004
    ..The prototype detector array will be evaluated with radioisotope sources and medical imaging phantoms.
  8. Neonatal Chest Phantom for Computed Radiography Testing
    Steven Don; Fiscal Year: 2001
    ..With the extension to a new class of digital x-ray imaging phantoms, the potential market should exceed $150,000,000.
  9. NOVEL PHANTOM FOR SPECT AND PET IMAGING
    FRANK DIFILIPPO; Fiscal Year: 2000
    ..The phantom will be used for acceptance testing, quality assurance, performance comparisons, and research for SPECT and PET scanners. ..
  10. IMAGING SOFTWARE & METHODS FOR MAPPING BRAIN DEVELOPMENT
    Allan Reiss; Fiscal Year: 2004
    ..of the reliability and validity of the methods and algorithms comprising this software by utilization of imaging phantoms, simulations and advanced statistical procedures and, (c) the evaluation of the utility of this software as ..
  11. Very-High-Frequency Ultrasound Imaging With Coded Signals and Annular Arrays
    Jonathan Mamou; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  12. A Beta-Sensitive Probe System for Use in Endoscopy
    RAYMOND RAYLMAN; Fiscal Year: 2002
    ..abstract_text> ..
  13. Data Consistency Based Motion Artifact Reduction for Head CT
    Hengyong Yu; Fiscal Year: 2008
    ..Hence, the proposed techniques promise to be translated for clinical use and should generate great healthcare benefits, especially for children. [unreadable] [unreadable] [unreadable]..
  14. Prediction of Second Cancer Risks for Children Treated with Proton - vs. - Photon
    Wayne D Newhauser; Fiscal Year: 2010
    ..In the future, we expect that the lower-risk treatments will result in fewer second cancers and this will translate into longer, higher-quality lives for survivors of childhood cancer (presently 270,000 persons in the United States). ..
  15. Non-Invasive Localization of Vulnerable Plaques
    Cynthia McCollough; Fiscal Year: 2009
    ....
  16. New Scanning Methods for 3-D Breast Ultrasound
    Jesse Yen; Fiscal Year: 2006
    ..A series of water tank and tissue phantom experiments will be performed to evaluate imaging performance in terms of resolution, contrast, and signal-to-noise ratio. ..
  17. Resolution requirements for mammographic displays
    Ehsan Samei; Fiscal Year: 2004
    ..The results will be used to formulate recommendations to the breast imaging community concerning display resolution criteria for safe and optimized soft-copy display of digital mammograms. ..
  18. Phase-Contrast Imaging of Microvascular Stucture
    MARK ANASTASIO; Fiscal Year: 2006
    ..The successful completion of our proposed research will establish in-line phase-contrast tomography as an effective and important modality for imaging microvascular structure. [unreadable] [unreadable]..
  19. Bi-Plane Correlation Imaging: Detection of Lung Cancer
    Ehsan Samei; Fiscal Year: 2007
    ..The findings will be used to substantiate the capability of BCI for improving the early detection of lung nodules and to optimize its performance on actual clinical cases. ..
  20. 31P/1H MRI Measurement of Bone Mineralization
    Yaotang Wu; Fiscal Year: 2008
    ..abstract_text> ..
  21. In-vivo intravascular autoradiography with storage phosphor detector
    POLAD SHIKHALIEV; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  22. Image Reconstruction with Solid Srate SPECR
    LAWRENCE ZENG; Fiscal Year: 2005
    ..abstract_text> ..
  23. Early Detection of Lung Cancer via Bi Plane Correlation
    Ehsan Samei; Fiscal Year: 2002
    ..The findings will be used to demonstrate the capability of the approach for improving the detection of lung nodules, and thus the prognosis of lung cancer. ..
  24. Detection of neonatal ventricular hemorrhage using EIT
    Rosalind Sadleir; Fiscal Year: 2006
    ..These data will be analyzed to determine the best way of separating artifacts produced by shape changes and other body impedance changes from the bleeding process. ..
  25. Breast Cancer Imaging Using a Solid-State SPECT Camera
    G Zeng; Fiscal Year: 2005
    ..abstract_text> ..
  26. 3-D Transrectal Ultrasound with 2-D Arrays
    JESSE T P YEN; Fiscal Year: 2010
    ..Lastly, a small number of in vitro experiments of canine prostates will be done. ..
  27. Local Tomography for Radiation Therapy Tumor Imaging
    MARK ANASTASIO; Fiscal Year: 2005
    ..By increasing the conformality of the radiation therapy treatment procedure, the chances of survival for cancer patients could be improved while simultaneously minimizing the risk of radiation-induced complications. ..
  28. Radio-Immunotherapy (RIT) Planning Using SPECT
    LAWRENCE ZENG; Fiscal Year: 2004
    ..Novel image reconstruction algorithms will be developed to provided quantitative SPECT images. Our hypothesis will be verified through human observer studies and Channelized Hotelling observer studies. ..
  29. Wide-bore Short-bore 3.0T MRI Neuroscanner
    Peter van Zijl; Fiscal Year: 2002
    ..The 3T is essential for continued high-quality state-of-the-art research at our institutions. ..
  30. Diffusion Tensor Imaging of Wallerian Degeneration in MS
    Khader Hasan; Fiscal Year: 2009
    ..This tool will also help in the fusion of multi-modal MRI data for a robust segmentation of the subregions of CC and 1C. The DTI measures, after accounting for the age and gender dependence will be correlated with the clinical measures. ..
  31. QUANTITATION OF THE BOLD EFFECT IN FUNCTIONAL MRI
    Peter van Zijl; Fiscal Year: 2002
    ..This understanding should facilitate optimal design of fMRI experiments in terms of the most suitable MRI pulse sequence parameters to obtain maximum effects. ..
  32. TOMOGRAPHIC DOSIMETRY PHANTOMS FOR PEDIATRIC RADIOLOGY
    Wesley Bolch; Fiscal Year: 2002
    ....
  33. US Prostate Cancer Detection with Dutasteride Pretreatment
    Ethan Halpern; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  34. Accurate, easy-to-commission radiotherapy beam models
    Bruce Faddegon; Fiscal Year: 2008
    ..This will allow clinics around the country to take advantage of the computational accuracy of this state-of-the-art clinical tool. [unreadable] [unreadable]..
  35. PORTABLE DEVICE FOR INSTANT DIAGNOSIS OF PNEUMOTHORAX
    Hansen Mansy; Fiscal Year: 2002
    ..PROPOSED COMMERCIAL APPLICATION: Not Available ..
  36. Intravascular Photoacoustic Imaging of Atherosclerotic Plaques
    STANISLAV EMELIANOV; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  37. K-Space energy spectrum analysis for echo-planar imaging
    Nan kuei Chen; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  38. Quantification of coronary calcium mass by dual energy fluoroscopy
    Sabee Molloi; Fiscal Year: 2009
    ..Dual-energy imaging, because of its motion insensitivity, can serve as a foundation for quantitative cardiac analysis to proceed. ..
  39. Pressure and Flow-Induced Remodeling of Coronary Arteries
    Ghassan S Kassab; Fiscal Year: 2010
    ..The long-term goal of this research is to develop optimal therapies to restore the oxidative balance in CAD. ..
  40. Microwave Thermal Monitoring for Breast Hyperthermia
    PAUL MEANEY; Fiscal Year: 2002
    ..It will set the stage for future treatment/monitoring systems targeting other anatomical sites. ..
  41. FUNCTIONAL MAGNETIC RESONANCE STUDIES OF THE BRAIN
    Peter van Zijl; Fiscal Year: 2002
    ..Our fourth and final aim is to implement the new technologies on the clinical scanner and to optimize their use for a fast and specific clinical stroke exam. ..
  42. Fractional flow reserve measurement based on coronary angiographic images
    SABEE Y MOLLOI; Fiscal Year: 2010
    ..This quantification technique could be used to measure fractional flow reserve in patients undergoing standard coronary arteriography. ..
  43. Academy of Molecular Imaging 2006 Annual Meeting
    Sanjiv Gambhir; Fiscal Year: 2006
    ..The annual conference is being held March 25-29, 2006 at the Gaylord Palms Resort Hotel and Convention Center in Orlando, Florida. [unreadable] [unreadable] [unreadable]..
  44. SPECT with pinholes separated by slats for high-sensitivity complete imaging
    SCOTT DEAN METZLER; Fiscal Year: 2010
    ..Thus, clinical and research scans that are likely to benefit from this new technique include brain, breast, limb, as well as some pediatric and animal applications. ..
  45. Smash Contrast-Enhanced 3D MR Angiography
    Robert Edelman; Fiscal Year: 2002
    ....
  46. Thick scintillation detector with continuous positioning & DOI capability for PET
    Suleman Surti; Fiscal Year: 2008
    ..Hence, thick continuous detectors have the potential to significantly impact the clinical imaging situation and the resultant patient treatment. [unreadable] [unreadable] [unreadable]..
  47. Quantitative Imaging with High Frequency Ultrasound
    Emad Ebbini; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  48. Correlative Imaging of Tumor Angiogenesis
    Sanjiv Gambhir; Fiscal Year: 2004
    ..We plan to perform pharmacokinetics and toxicology studies with preclinical materials and prepare an agent for gamma and SPECT imaging in clinical studies and file an IRB for cancer angiogenesis evaluation. ..
  49. RECONSTRUCTION ALGORITHM FOR MULTI-SLICE SPIRAL X-RAY CT
    Frederic Noo; Fiscal Year: 2004
    ..Indirectly, this project will have significant impacts on all aspects of medical imaging - particularly in oncology, angiography, evaluation of infections and cardiac diseases, trauma, and radiotherapy. ..
  50. VERY-HIGH-FREQUENCY ULTRASOUND ARRAYS FOR OPHTHALMOLOGY
    Jeffrey Ketterling; Fiscal Year: 2005
    ..Concepts are validated and refined using scans of in-vitro porcine eyes and in-vivo rabbit eyes. ..
  51. MRI Diffusion Correlates of Neuronal Activity
    JAMES MAC FALL; Fiscal Year: 2005
    ..abstract_text> ..
  52. Microwave Thermal Monitoring for Breast Hyperthermia
    PAUL MEANEY; Fiscal Year: 2003
    ..It will set the stage for future treatment/monitoring systems targeting other anatomical sites. ..
  53. Dynamic Multi-Modality Imaging for Radiotherapy
    Janelle Molloy; Fiscal Year: 2005
    ..The proposed system will find application in the areas of image-guided biopsy, brachytherapy, and education, as well as in radiation therapy treatment planning and daily verification. ..
  54. Advances in Skeletal Dosimetry Through Microimaging
    Wesley Bolch; Fiscal Year: 2006
    ..abstract_text> ..
  55. MRI-Based Method to Evaluate Engineered Cartilage
    Corey Neu; Fiscal Year: 2006
    ..The deformation measurements will be used to approximate the 3D finite strain tensor field throughout normal and tissue engineered cartilage. ..
  56. Smash Contrast-Enhanced 3D MR Angiography
    Robert Edelman; Fiscal Year: 2003
    ....
  57. An Integrated PET-MRI System for Molecular Imaging
    Bernd Pichler; Fiscal Year: 2005
    ..abstract_text> ..
  58. Two-dimensional MR Spectroscopic Characterization of HE
    Michael Thomas; Fiscal Year: 2006
    ..Minimal spectral overlap leading to less ambiguous assignment and better quantitation of glutamate/glutamine, GABA, myo-inositol, threonine, glucose, taurine and glutathione, will be a major outcome of this work. ..
  59. 3D Time-resolved Tomographic Interventional Platform
    Guang Hong Chen; Fiscal Year: 2004
    ....
  60. Integrated Tomosynthetic Perfusion and Cone-beam CT Imaging on a C-arm Gantry
    Guang Hong Chen; Fiscal Year: 2009
    ..The new interventional platform will not only benefit those at researchcenters,but also will enable image-guided interventional stroke treatmentsfor hospitals without advanced imaging facilities. ..
  61. Improved MRI techniques for measurement of absolute temperature distributions
    NICHOLAS TODD; Fiscal Year: 2008
    ..A temporally constrained reconstruction algorithm has been shown to be capable of reducing scan time and can also be implemented with any pulse sequence. [unreadable] [unreadable] [unreadable]..
  62. MrSPA: Integrated tools and development platform for magnetic resonance research
    Karl A Young; Fiscal Year: 2010
    ....
  63. Technology Development in Optical Coherence Tomography
    Emily McDowell; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  64. ULTRASONIC WAVE DISTORTION MEASUREMENT AND CORRECTION
    ROBERT WAAG; Fiscal Year: 2001
    ....
  65. MR Studies of Myocardial Creatine Kinase Metabolism
    PAUL BOTTOMLEY; Fiscal Year: 2007
    ....
  66. SODIUM IMAGING IN ISCHEMIC HEART DISEASE
    PAUL BOTTOMLEY; Fiscal Year: 2002
    ..The availability of thousands of clinical MRI scanners offers a great opportunity for advancing 23Na MRI as a tool for assessing sodium pump function in human heart disease. ..
  67. ULTRASONIC WAVE DISTORTION MEASUREMENT AND CORRECTION
    ROBERT WAAG; Fiscal Year: 2008
    ..abstract_text> ..
  68. AUTOMATIC CORRECTION OF MOTION ARTIFACTS IN MR IMAGES
    Armando Manduca; Fiscal Year: 2001
    ..They are applicable to both conventional and fast scan applications, and may be adaptable to many non- motion sources of artifacts as well. ..
  69. Ultrasound-Guided MRI
    David Feinberg; Fiscal Year: 2005
    ..Ultrasound-guided MRI should permit dramatic improvements in imaging the heart or abdominal organs that are affected by physiological motion. ..
  70. Improved 3D MRI with cylindrical trajectories
    David Feinberg; Fiscal Year: 2004
    ..During the commercialization phase the developed set of pulse sequences will be ported for suitable hardware and software platforms of all major MR hardware manufacturers. ..
  71. Helical Pinhole SPECT for Small-Scale Quantification
    SCOTT METZLER; Fiscal Year: 2006
    ..Another long-term vision for this system is its miniaturization to a table-top research instrument. [unreadable] [unreadable]..
  72. Accurate and Precise Calibrations for Pinhole SPECT
    SCOTT METZLER; Fiscal Year: 2006
    ..These models are important for accurate quantification. Our goal is to develop the techniques and RS necessary for reconstruction resolutions in the range of approximately 0.5 mm or less. ..
  73. Image-Guided Otologic Surgery
    Robert Labadie; Fiscal Year: 2004
    ..It is anticipated that this system will make ear surgery safer and more efficient. ..
  74. Robotic Mastoidectomy
    Robert Labadie; Fiscal Year: 2008
    ..It is hypothesized that this strategy will be more efficient than either the human or robotic interventions examined in Specific Aim 2. [unreadable] [unreadable] [unreadable]..
  75. AUTOMATIC CORRECTION OF MOTION ARTIFACTS IN MR IMAGES
    Armando Manduca; Fiscal Year: 2007
    ..They represent perhaps the most flexible and universally applicable techniques for the correction of motion (and other) artifacts in MR imaging. ..
  76. Mouse Modeling Techniques for Bioluminescence Tomography
    Wenxiang Cong; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  77. Software for the Analysis and Visualization of High Angular Resolution DTI Data
    Lawrence Frank; Fiscal Year: 2009
    ....