electrodes

Summary

Summary: Mediums used between an electric conductor and the object to which the current is to be applied. In electrotherapy, electrodes are instruments with a point or surface from which to transmit electric current to the body of a patient or to another instrument; in electrodiagnosis, they are needles or metal plates used to stimulate or record the electrical activity of tissue. (From Dorland, 28th ed)

Articles from Journal RESEARCH

Top Publications

  1. ncbi EEG source imaging
    Christoph M Michel
    Functional Brain Mapping Laboratory, Neurology Clinic, University Hospital of Geneva, 24 Rue Micheli du Crest, 1211 Geneva, Switzerland
    Clin Neurophysiol 115:2195-222. 2004
  2. pmc Percutaneous radiofrequency ablation with multiple electrodes for medium-sized hepatocellular carcinomas
    Jung Lee
    Seoul National University Hospital, Seoul 110 744, Korea
    Korean J Radiol 13:34-43. 2012
  3. ncbi Transfer of large-area graphene films for high-performance transparent conductive electrodes
    Xuesong Li
    Department of Mechanical Engineering and the Texas Materials Institute, The University of Texas at Austin, Texas 78712 0292, USA
    Nano Lett 9:4359-63. 2009
  4. ncbi Modeling the current distribution during transcranial direct current stimulation
    Pedro Cavaleiro Miranda
    Faculty of Sciences, Institute of Biophysics and Biomedical Engineering, University of Lisbon, Campo Grande, 1749 016 Lisbon, Portugal
    Clin Neurophysiol 117:1623-9. 2006
  5. ncbi Nanostructured carbon-metal oxide composite electrodes for supercapacitors: a review
    Mingjia Zhi
    Department of Mechanical and Aerospace Engineering, West Virginia University, Morgantown, WV 26505 6106, USA
    Nanoscale 5:72-88. 2013
  6. pmc High-speed graphene transistors with a self-aligned nanowire gate
    Lei Liao
    Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA
    Nature 467:305-8. 2010
  7. ncbi Dry-contact and noncontact biopotential electrodes: methodological review
    Yu Mike Chi
    Department of Electrical and Computer Engineering, Jacobs School of Engineering, University of California, San Diego, CA 92093, USA
    IEEE Rev Biomed Eng 3:106-19. 2010
  8. ncbi Epidermal electronics
    Dae Hyeong Kim
    Department of Materials Science and Engineering, Beckman Institute for Advanced Science and Technology, and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Science 333:838-43. 2011
  9. ncbi Optimizing clinical performance and geometrical robustness of a new electrode device for intracranial tumor electroporation
    Faisal Mahmood
    Copenhagen University Hospital Herlev, Center for Experimental Drug and Gene Electrotransfer, Department of Oncology, Herlev Ringvej 75, 2730 Herlev, Denmark
    Bioelectrochemistry 81:10-6. 2011
  10. ncbi Graphene-wrapped sulfur particles as a rechargeable lithium-sulfur battery cathode material with high capacity and cycling stability
    Hailiang Wang
    Department of Chemistry, Stanford University, Stanford, California 94305, United States
    Nano Lett 11:2644-7. 2011

Detail Information

Articles from Journal RESEARCH1

Publications408 found, 100 shown here

  1. ncbi EEG source imaging
    Christoph M Michel
    Functional Brain Mapping Laboratory, Neurology Clinic, University Hospital of Geneva, 24 Rue Micheli du Crest, 1211 Geneva, Switzerland
    Clin Neurophysiol 115:2195-222. 2004
    ..By introducing reasonable a priori constraints, the inverse problem can be solved and the most probable sources in the brain at every moment in time can be accurately localized...
  2. pmc Percutaneous radiofrequency ablation with multiple electrodes for medium-sized hepatocellular carcinomas
    Jung Lee
    Seoul National University Hospital, Seoul 110 744, Korea
    Korean J Radiol 13:34-43. 2012
    To prospectively evaluate the safety and short-term therapeutic efficacy of switching monopolar radiofrequency ablation (RFA) with multiple electrodes to treat medium-sized (3.1-5.0 cm), hepatocellular carcinomas (HCC).
  3. ncbi Transfer of large-area graphene films for high-performance transparent conductive electrodes
    Xuesong Li
    Department of Mechanical Engineering and the Texas Materials Institute, The University of Texas at Austin, Texas 78712 0292, USA
    Nano Lett 9:4359-63. 2009
    ..The improved transfer processes will also be of great value for the fabrication of electronic devices such as field effect transistor and bilayer pseudospin field effect transistor devices...
  4. ncbi Modeling the current distribution during transcranial direct current stimulation
    Pedro Cavaleiro Miranda
    Faculty of Sciences, Institute of Biophysics and Biomedical Engineering, University of Lisbon, Campo Grande, 1749 016 Lisbon, Portugal
    Clin Neurophysiol 117:1623-9. 2006
    ..To investigate the spatial distribution of the magnitude and direction of the current density in the human head during transcranial direct current stimulation (tDCS)...
  5. ncbi Nanostructured carbon-metal oxide composite electrodes for supercapacitors: a review
    Mingjia Zhi
    Department of Mechanical and Aerospace Engineering, West Virginia University, Morgantown, WV 26505 6106, USA
    Nanoscale 5:72-88. 2013
    This paper presents a review of the research progress in the carbon-metal oxide composites for supercapacitor electrodes. In the past decade, various carbon-metal oxide composite electrodes have been developed by integrating metal oxides ..
  6. pmc High-speed graphene transistors with a self-aligned nanowire gate
    Lei Liao
    Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA
    Nature 467:305-8. 2010
    ..A Co(2)Si-Al(2)O(3) core-shell nanowire is used as the gate, with the source and drain electrodes defined through a self-alignment process and the channel length defined by the nanowire diameter...
  7. ncbi Dry-contact and noncontact biopotential electrodes: methodological review
    Yu Mike Chi
    Department of Electrical and Computer Engineering, Jacobs School of Engineering, University of California, San Diego, CA 92093, USA
    IEEE Rev Biomed Eng 3:106-19. 2010
    ..in wireless, mobile-based healthcare has driven significant interest towards developing alternative biopotential electrodes for patient physiological monitoring...
  8. ncbi Epidermal electronics
    Dae Hyeong Kim
    Department of Materials Science and Engineering, Beckman Institute for Advanced Science and Technology, and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Science 333:838-43. 2011
    ..We used this type of technology to measure electrical activity produced by the heart, brain, and skeletal muscles and show that the resulting data contain sufficient information for an unusual type of computer game controller...
  9. ncbi Optimizing clinical performance and geometrical robustness of a new electrode device for intracranial tumor electroporation
    Faisal Mahmood
    Copenhagen University Hospital Herlev, Center for Experimental Drug and Gene Electrotransfer, Department of Oncology, Herlev Ringvej 75, 2730 Herlev, Denmark
    Bioelectrochemistry 81:10-6. 2011
    ..For example, a 2 mm displacement of 6 electrodes yields 14% better compliance with the clinical parameters, compared to the prototype, and additionally makes the ..
  10. ncbi Graphene-wrapped sulfur particles as a rechargeable lithium-sulfur battery cathode material with high capacity and cycling stability
    Hailiang Wang
    Department of Chemistry, Stanford University, Stanford, California 94305, United States
    Nano Lett 11:2644-7. 2011
    ..The resulting graphene-sulfur composite showed high and stable specific capacities up to ∼600 mAh/g over more than 100 cycles, representing a promising cathode material for rechargeable lithium batteries with high energy density...
  11. ncbi Self-assembled graphene hydrogel via a one-step hydrothermal process
    Yuxi Xu
    Department of Chemistry, Tsinghua University, Beijing 100084, People s Republic of China
    ACS Nano 4:4324-30. 2010
    ..The high-performance SGH with inherent biocompatibility of carbon materials is attractive in the fields of biotechnology and electrochemistry, such as drug-delivery, tissue scaffolds, bionic nanocomposites, and supercapacitors...
  12. ncbi Increased power generation in a continuous flow MFC with advective flow through the porous anode and reduced electrode spacing
    Shaoan Cheng
    Department of Civil and Environmental Engineering, The Penn State Hydrogen Energy H2E Center, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Environ Sci Technol 40:2426-32. 2006
    ..air-cathode microbial fuel cell (MFC) has previously been shown to increase when the spacing between the electrodes is decreased from 4 to 2 cm...
  13. pmc Ultrasensitive electrochemical immunosensor for oral cancer biomarker IL-6 using carbon nanotube forest electrodes and multilabel amplification
    Ruchika Malhotra
    Department of Chemistry and Institute of Materials Science, University of Connecticut, 55 North Eagleville Road, Storrs, Connecticut 06269, USA
    Anal Chem 82:3118-23. 2010
    ....
  14. ncbi Emerging transparent electrodes based on thin films of carbon nanotubes, graphene, and metallic nanostructures
    David S Hecht
    Unidym, 1244 Reamwood Dr, Sunnyvale, CA 94070, USA
    Adv Mater 23:1482-513. 2011
    Transparent electrodes are a necessary component in many modern devices such as touch screens, LCDs, OLEDs, and solar cells, all of which are growing in demand...
  15. pmc Shewanella secretes flavins that mediate extracellular electron transfer
    Enrico Marsili
    BioTechnology Institute and Department of Microbiology, University of Minnesota, St Paul, MN 55108, USA
    Proc Natl Acad Sci U S A 105:3968-73. 2008
    ..Removal of riboflavin from biofilms reduced the rate of electron transfer to electrodes by >70%, consistent with a role as a soluble redox shuttle carrying electrons from the cell surface to ..
  16. ncbi Exoelectrogenic bacteria that power microbial fuel cells
    Bruce E Logan
    Department of Civil and Environmental Engineering, Bruce E Logan is at the Hydrogen Energy Center, Penn State University, University Park, Pennsylvania 16802, USA
    Nat Rev Microbiol 7:375-81. 2009
    ..To understand bacterial versatility in mechanisms used for current generation, this Progress article explores the underlying reasons for exocellular electron transfer, including cellular respiration and possible cell-cell communication...
  17. ncbi Graphene-based electrodes
    Xiao Huang
    School of Materials Science and Engineering, Nanyang Technological University, Singapore, Singapore
    Adv Mater 24:5979-6004. 2012
    ..Graphene-based electrodes, fabricated from mechanically cleaved graphene, chemical vapor deposition (CVD) grown graphene, or massively ..
  18. pmc Electricity production by Geobacter sulfurreducens attached to electrodes
    Daniel R Bond
    Department of Microbiology, University of Massachusetts, Amherst, MA 01003, USA
    Appl Environ Microbiol 69:1548-55. 2003
    Previous studies have suggested that members of the Geobacteraceae can use electrodes as electron acceptors for anaerobic respiration...
  19. ncbi Direct electron transfer between copper-containing proteins and electrodes
    Sergey Shleev
    Department of Analytical Chemistry, Lund University, P O Box 124, SE 221 00 Lund, Sweden
    Biosens Bioelectron 20:2517-54. 2005
    ..It is shown that long-range electron transfer between these enzymes and electrodes can be established, and the mechanistic schemes of the DET processes are proposed.
  20. ncbi Electrochemical interrogations of the Mtr cytochromes from Shewanella: opening a potential window
    Mackenzie Firer-Sherwood
    Department of Chemistry, Boston University, 590 Commonwealth Ave, Boston, MA 02215, USA
    J Biol Inorg Chem 13:849-54. 2008
    ..These data are taken together to suggest a model of electron transport where a wide window of potential allows for charge transfer from the cellular interior to the exterior to support bioenergetics...
  21. ncbi Virus-enabled synthesis and assembly of nanowires for lithium ion battery electrodes
    Ki Tae Nam
    Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Science 312:885-8. 2006
    ....
  22. ncbi Efficiency enhancement of organic solar cells using transparent plasmonic Ag nanowire electrodes
    Myung Gyu Kang
    Department of Electrical Engineering and Computer Science, The University of Michigan, Ann Arbor, Michigan 48109, USA
    Adv Mater 22:4378-83. 2010
    ..photo-current and power conversion efficiency of organic solar cells using periodic Ag nanowires as transparent electrodes are reported, as compared to the device with conventional ITO electrodes...
  23. ncbi Electron transport properties of atomic carbon nanowires between graphene electrodes
    Lei Shen
    Department of Physics, 2 Science Drive 3, National University of Singapore, Singapore 117542, Singapore
    J Am Chem Soc 132:11481-6. 2010
    ..As such, the epoxy groups might be the origin of experimentally observed low conductance in the carbon chain. Moreover, double-atomic carbon chains exhibit a negative differential resistance effect...
  24. pmc A glucose biofuel cell implanted in rats
    Philippe Cinquin
    Laboratoire TIMC IMAG Techniques de l Ingénierie Médicale et de la Complexité Informatique, Mathématiques et Applications de Grenoble, Centre National de la Recherche Scientifique, Universite Joseph Fourier, Grenoble, France
    PLoS ONE 5:e10476. 2010
    ..This GBFC, with electrodes of 0.133 mL, produced a peak specific power of 24...
  25. pmc A low-power bio-potential acquisition system with flexible PDMS dry electrodes for portable ubiquitous healthcare applications
    Chih Yuan Chen
    Department of Electric Engineering, National Cheng Kung University, 701 Tainan, Taiwan
    Sensors (Basel) 13:3077-91. 2013
    ..acquisition system for portable ubiquitous healthcare applications using flexible polydimethylsiloxane dry electrodes (FPDEs) and a low-power recording circuit...
  26. ncbi Highly flexible silver nanowire electrodes for shape-memory polymer light-emitting diodes
    Zhibin Yu
    Department of Materials Science and Engineering, Henry Samueli School of Engineering and Applied Science, University of California Los Angeles, CA 90095, USA
    Adv Mater 23:664-8. 2011
    ..Large deformation shape change and recovery of the PLEDs to various bistable curvatures result in minimal loss of electroluminescence performance...
  27. ncbi Dual frequency dielectrophoresis with interdigitated sidewall electrodes for microfluidic flow-through separation of beads and cells
    Lisen Wang
    Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA
    Electrophoresis 30:782-91. 2009
    ..in microfluidics by dual frequency coupled dielectrophoresis (DEP) forces enabled by vertical interdigitated electrodes embedded in the channel sidewalls...
  28. ncbi Self-assembly and sensor response of photosynthetic reaction centers on screen-printed electrodes
    Vijayender Bhalla
    Department of Physics, Concordia University, Montreal, Quebec, Canada
    Anal Chim Acta 707:184-90. 2011
    Photosynthetic reaction centers were immobilized onto gold screen-printed electrodes (Au-SPEs) using a self-assembled monolayer (SAM) of mercaptopropionic acid (MPA) which was deliberately defective in order to achieve effective mediator ..
  29. ncbi Level of action of cathodal DC polarisation induced inhibition of the human motor cortex
    Michael A Nitsche
    Department of Clinical Neurophysiology, University of Goettingen, Robert Koch Str 40, 37075, Goettingen, Germany
    Clin Neurophysiol 114:600-4. 2003
    ..To induce prolonged motor cortical excitability reductions by transcranial direct current stimulation in the human...
  30. ncbi Freestanding three-dimensional graphene/MnO2 composite networks as ultralight and flexible supercapacitor electrodes
    Yongmin He
    School of Physical Science and Technology, Lanzhou University, Lanzhou 730000, People s Republic of China
    ACS Nano 7:174-82. 2013
    ..S/cm), and flexible three-dimensional (3D) graphene networks, loaded with MnO(2) by electrodeposition, as the electrodes of a flexible supercapacitor...
  31. pmc Towards electrosynthesis in shewanella: energetics of reversing the mtr pathway for reductive metabolism
    Daniel E Ross
    The Biotechnology Institute, University of Minnesota Twin Cities, St Paul, Minnesota, United States of America
    PLoS ONE 6:e16649. 2011
    Bioelectrochemical systems rely on microorganisms to link complex oxidation/reduction reactions to electrodes. For example, in Shewanella oneidensis strain MR-1, an electron transfer conduit consisting of cytochromes and structural ..
  32. pmc Microbial biofilm voltammetry: direct electrochemical characterization of catalytic electrode-attached biofilms
    Enrico Marsili
    Biotechnology Institute, University of Minnesota, St Paul, MN 55108, USA
    Appl Environ Microbiol 74:7329-37. 2008
    While electrochemical characterization of enzymes immobilized on electrodes has become common, there is still a need for reliable quantitative methods for study of electron transfer between living cells and conductive surfaces...
  33. ncbi Electronically conductive phospho-olivines as lithium storage electrodes
    Sung Yoon Chung
    Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA
    Nat Mater 1:123-8. 2002
    ..In a conventional cell design, they may allow development of lithium batteries with the highest power density yet...
  34. pmc The Mtr respiratory pathway is essential for reducing flavins and electrodes in Shewanella oneidensis
    Dan Coursolle
    Biotechnology Institute, University of Minnesota, Paul, MN 55108, USA
    J Bacteriol 192:467-74. 2010
    ..Given the involvement of external flavins in the reduction of electrodes, we monitored current production by Mtr respiratory pathway mutants in three-electrode bioreactors under ..
  35. pmc Chronic, multisite, multielectrode recordings in macaque monkeys
    Miguel A L Nicolelis
    Department of Neurobiology, Duke University, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 100:11041-6. 2003
    ..This method should benefit neurophysiological investigation of learning, perception, and sensorimotor integration in primates and the development of neuroprosthetic devices...
  36. ncbi Sequence-specific detection of femtomolar DNA via a chronocoulometric DNA sensor (CDS): effects of nanoparticle-mediated amplification and nanoscale control of DNA assembly at electrodes
    Jiong Zhang
    Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China
    J Am Chem Soc 128:8575-80. 2006
    ..is based on a "sandwich" detection strategy, which involves capture probe DNA immobilized on gold electrodes and reporter probe DNA labeled with gold nanoparticles that flank the target DNA sequence...
  37. ncbi Small applied electric fields guide migration of hippocampal neurons
    Li Yao
    School of Medical Sciences, University of Aberdeen, Aberdeen, Scotland, UK
    J Cell Physiol 216:527-35. 2008
    ..This work demonstrates that rat hippocampal neurons respond to applied EFs with directional migration and raises the possibility that EFs may be used as a cue to direct neuronal migration in novel strategies to repair the CNS...
  38. ncbi Enzymatic biofuel cells for implantable and microscale devices
    Scott Calabrese Barton
    Department of Chemical Engineering, Columbia University, New York, New York 10027, USA
    Chem Rev 104:4867-86. 2004
  39. ncbi Epileptic source localization with high density EEG: how many electrodes are needed?
    G Lantz
    Functional Brain Mapping Laboratory, Department of Neurology, University Hospital of Geneva, 24, Rue Micheli du Crest, CH 1211, Geneva, Switzerland
    Clin Neurophysiol 114:63-9. 2003
    ..Recently, however, EEG systems which allow for quick (10-20min) application of, and recording from, up to 125 electrodes have become available...
  40. ncbi In situ prepared transparent polyaniline electrode and its application in bifacial dye-sensitized solar cells
    Qidong Tai
    School of Physics and Technology, Key Laboratory of Artificial Micro Nano Structures of Ministry of Education, Wuhan University, Wuhan 430072, China
    ACS Nano 5:3795-9. 2011
    Highly uniform and transparent polyaniline (PANI) electrodes that can be used as counter electrodes in dye-sensitized solar cells (DSSCs) were prepared by a facile in situ polymerization method...
  41. pmc Enhanced perception of user intention by combining EEG and gaze-tracking for brain-computer interfaces (BCIs)
    Jong Suk Choi
    Division of Electronics and Electrical Engineering, Dongguk University, 26 Pil dong 3 ga, Jung Gu, Seoul 100 715, Korea
    Sensors (Basel) 13:3454-72. 2013
    ..The experimental results showed that the accuracy of proposed method was higher than the other methods...
  42. ncbi Dielectrophoresis-based cell manipulation using electrodes on a reusable printed circuit board
    Kidong Park
    School of Electrical and Computer Engineering, Purdue University, West Lafayette, IN 47907, USA
    Lab Chip 9:2224-9. 2009
    ..In this study, we present the use of interdigitated electrodes on a printed circuit board (PCB) that can be reused to manipulate and position HeLa cells and polystyrene ..
  43. ncbi Interdigitated comb-like electrodes for continuous separation of malignant cells from blood using dielectrophoresis
    Anas Alazzam
    Department of Mechanical and Industrial Engineering, Concordia University, Montreal, QC, Canada
    Electrophoresis 32:1327-36. 2011
    ..Alternatively, it may also be used to detect cancer recurrences...
  44. ncbi Coating graphene paper with 2D-assembly of electrocatalytic nanoparticles: a modular approach toward high-performance flexible electrodes
    Fei Xiao
    School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, Singapore 637457
    ACS Nano 6:100-10. 2012
    The development of flexible electrodes is of considerable current interest because of the increasing demand for modern electronics, portable medical products, and compact energy devices...
  45. ncbi Mutual enhancement of the current density and the coulombic efficiency for a bioanode by entrapping bi-enzymes with Os-complex modified electrodeposition paints
    Minling Shao
    Analytische Chemie Elektroanalytik and Sensorik, Ruhr Universitat Bochum, Universitatsstr 150, D 44780 Bochum, Germany
    Biosens Bioelectron 40:308-14. 2013
    ..We propose the use of this bioanode in biofuel cells with increased current density and coulombic efficiency...
  46. pmc Electrochemical measurement of electron transfer kinetics by Shewanella oneidensis MR-1
    Daniel Baron
    Biotechnology Institute, University of Minnesota, St Paul, Minnesota 55108, USA
    J Biol Chem 284:28865-73. 2009
    Shewanella oneidensis strain MR-1 can respire using carbon electrodes and metal oxyhydroxides as electron acceptors, requiring mechanisms for transferring electrons from the cell interior to surfaces located beyond the cell...
  47. ncbi Workfunction-tunable, N-doped reduced graphene transparent electrodes for high-performance polymer light-emitting diodes
    Jin Ok Hwang
    Department of Materials Science and Engineering, KI for the Nanocentury, KAIST, Daejeon, 305 701, Republic of Korea
    ACS Nano 6:159-67. 2012
    ..0 cd/A for FTO and 7.0 cd/A for N-doped graphene at 17,000 cd/m(2)). The reduced barrier for electron injection from a workfunction-tunable, N-doped reduced graphene cathode offered this remarkable device performance...
  48. pmc Electrochemotherapy: technological advancements for efficient electroporation-based treatment of internal tumors
    D Miklavcic
    Faculty of Electrical Engineering, University of Ljubljana, Ljubljana, Slovenia
    Med Biol Eng Comput 50:1213-25. 2012
    ..New electrodes through which electric pulses are delivered to target tissue need to be designed with the aim to access target ..
  49. pmc Nanoelectrodes for determination of reactive oxygen and nitrogen species inside murine macrophages
    Yixian Wang
    Department of Chemistry and Biochemistry, Queens College City University of New York, Flushing, NY 11367, USA
    Proc Natl Acad Sci U S A 109:11534-9. 2012
    ..Micrometer-sized electrodes coated with Pt black have previously been used for selective and sensitive detection of ROS and RNS in ..
  50. ncbi Recent developments and applications of screen-printed electrodes in environmental assays--a review
    Meng Li
    State Key Laboratory of Bioreactor Engineering and Department of Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, PR China
    Anal Chim Acta 734:31-44. 2012
    Screen-printed electrodes (SPEs), which are used as economical electrochemical substrates, have gone through significant improvements over the past few decades with respect to both their format and their printing materials...
  51. pmc Long-range electron transport in Geobacter sulfurreducens biofilms is redox gradient-driven
    Rachel M Snider
    National Research Council, Washington, DC 20001, USA
    Proc Natl Acad Sci U S A 109:15467-72. 2012
    ..The majority of these redox cofactors, however, seem to have oxidation potentials too negative to be involved in electron transport when acetate is the electron source...
  52. ncbi The conductivity of the human skull: results of in vivo and in vitro measurements
    T F Oostendorp
    Department of Medical Physics and Biophysics, University of Nijmegen, The Netherlands
    IEEE Trans Biomed Eng 47:1487-92. 2000
    ..For the in vivo measurement a small current was passed through the head by means of two electrodes placed on the scalp...
  53. ncbi Generation of photocurrents by bis-aniline-cross-linked Pt nanoparticle/photosystem I composites on electrodes
    Omer Yehezkeli
    Institute of Chemistry, Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    J Phys Chem B 114:14383-8. 2010
    ..The Fd bound to the matrix mediates the electron transfer toward the electrode and facilitates charge separation that results in enhanced generation of the photocurrent, ϕ (λ = 420 nm) = 3.8%, IPCE ∼ 0.5%...
  54. pmc A glucose fuel cell for implantable brain-machine interfaces
    Benjamin I Rapoport
    Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
    PLoS ONE 7:e38436. 2012
    ..The catalytic electrodes are separated by a Nafion membrane...
  55. pmc Cellobiose dehydrogenase modified electrodes: advances by materials science and biochemical engineering
    Roland Ludwig
    Food Biotechnology Laboratory, Department of Food Sciences and Technology, BOKU University of Natural Resources and Life Sciences, Vienna, Muthgasse 18, 1190 Vienna, Austria
    Anal Bioanal Chem 405:3637-58. 2013
    ..of CDH-based biosensors, which focus on (1) more efficient DET on chemically modified or nanostructured electrodes, (2) the synthesis of custom-made redox polymers for higher MET currents and (3) the engineering of enzymes and ..
  56. ncbi Mediatorless sugar/oxygen enzymatic fuel cells based on gold nanoparticle-modified electrodes
    Xiaoju Wang
    Laboratory of Inorganic Chemistry, Process Chemistry Centre, Abo Akademi University, 20500 Turku, Finland
    Biosens Bioelectron 31:219-25. 2012
    ..bilirubin oxidase (MvBOx), used as anodic and cathodic bioelements, respectively, were immobilised on gold electrodes modified with 20 nm AuNPs...
  57. pmc Textile electrodes for EEG recording--a pilot study
    Johan Löfhede
    School of Engineering, University of Borås, 501 90 Borås, Sweden
    Sensors (Basel) 12:16907-19. 2012
    ..Long-term EEG monitoring in newborns require that the electrodes don't harm the sensitive skin of the baby, an especially relevant feature for premature babies...
  58. ncbi High-performance supercapacitors based on poly(ionic liquid)-modified graphene electrodes
    Tae Young Kim
    Department of Materials Science and Engineering, Korea University, 5 1 Anam dong Seongbuk gu, Seoul 136 713, South Korea
    ACS Nano 5:436-42. 2011
    ..5 W·h/kg with a power density of 2.4 kW/kg. These results demonstrate the potential of the PIL:RG-O material as an electrode in high-performance supercapacitors...
  59. pmc Anode biofilm transcriptomics reveals outer surface components essential for high density current production in Geobacter sulfurreducens fuel cells
    Kelly P Nevin
    Department of Microbiology, University of Massachusetts, Amherst, Massachusetts, USA
    PLoS ONE 4:e5628. 2009
    ..by which Geobacter sulfurreducens transfers electrons through relatively thick (>50 microm) biofilms to electrodes acting as a sole electron acceptor were investigated...
  60. ncbi Characteristics of third-generation glucose biosensors based on Corynascus thermophilus cellobiose dehydrogenase immobilized on commercially available screen-printed electrodes working under physiological conditions
    Muhammad Nadeem Zafar
    Department of Biochemistry and Structural Biology, Lund University, Sweden
    Anal Biochem 425:36-42. 2012
    ..the ascomycete Corynascus thermophilus (CtCDH) immobilized on different commercially available screen-printed electrodes made of carbon (SPCEs), carboxyl-functionalized single-walled carbon nanotubes (SPCE-SWCNTs), or multiwalled ..
  61. pmc Long-distance electron transfer by G. sulfurreducens biofilms results in accumulation of reduced c-type cytochromes
    Ying Liu
    BioTechnology Institute and Department of Microbiology, University of Minnesota, 140 Gortner Laboratory, 1479 Gortner Ave St Paul MN 55108, USA
    ChemSusChem 5:1047-53. 2012
    So close, but yet so far: G. sulfurreducens c-type cytochromes become reduced as biofilms grow on electrodes beyond a few cell thicknesses, even if the electrode is poised well above the potential required to oxidize all cytochromes...
  62. pmc Bilirubin oxidase from Bacillus pumilus: a promising enzyme for the elaboration of efficient cathodes in biofuel cells
    Fabien Durand
    CRPP UPR 8641, Univ Bordeaux, F 33600, Pessac, France
    Biosens Bioelectron 35:140-6. 2012
    ..tsunodae BOD modified electrode. This makes BOD from B. pumilus an attractive new candidate for application in biofuel cells (BFCs) and biosensors...
  63. pmc Multiple-electrode radiofrequency ablations using Octopus® electrodes in an in vivo porcine liver model
    E S Lee
    Department of Radiology, Seoul NationalUniversity College of Medicine, Seoul, Republic of Korea
    Br J Radiol 85:e609-15. 2012
    The objective of this study was to determine the in vivo efficacy of radiofrequency ablation (RFA) in porcine liver using Octopus® electrodes for creating a large coagulation compared with RFA using clustered electrodes.
  64. ncbi An overview of the applications of graphene-based materials in supercapacitors
    Yi Huang
    Key Laboratory of Functional Polymer Materials and Centre for Nanoscale Science and Technology, Institute of Polymer Chemistry, College of Chemistry, Nankai University, 300071, Tianjin, China
    Small 8:1805-34. 2012
    ..Several key issues for improving the structure of graphene-based materials and for achieving better capacitor performance, along with the current outlook for the field, are also discussed...
  65. ncbi Formation of ZnMn2O4 ball-in-ball hollow microspheres as a high-performance anode for lithium-ion batteries
    Genqiang Zhang
    TUM CREATE Centre for Electromobility, Singapore
    Adv Mater 24:4609-13. 2012
    ....
  66. ncbi Assembly of graphene sheets into hierarchical structures for high-performance energy storage
    Shengyan Yin
    School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore
    ACS Nano 5:3831-8. 2011
    The electrodes with the hierarchical nanoarchitectures could offer a huge increase in energy storage capacity. However, the ability to achieve such hierarchical architectures on a multiple scale still has remained a great challenge...
  67. pmc Brain-computer interface based on generation of visual images
    Pavel Bobrov
    Institute of Higher Nervous Activity and Neurophysiology of Russian Academy of Sciences, Moscow, Russia
    PLoS ONE 6:e20674. 2011
    ....
  68. ncbi Facilitated ion transport in all-solid-state flexible supercapacitors
    Bong Gill Choi
    Department of Chemical and Biomolecular Engineering BK21 Program, KAIST, Daejeon 305 701, Republic of Korea
    ACS Nano 5:7205-13. 2011
    ..Therefore, this research provides new insight into the rational design and fabrication of all-solid-state flexible energy-storage devices as well as the fundamental understanding of ion and charge transport at the interface...
  69. ncbi Spinal cord stimulation electrode design: prospective, randomized, controlled trial comparing percutaneous and laminectomy electrodes-part I: technical outcomes
    Richard B North
    Department of Neurosurgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21287 7713, USA
    Neurosurgery 51:381-9; discussion 389-90. 2002
    ..successful because of recent technical improvements, particularly the development of multiple-contact electrodes supported by programmable implanted pulse generators...
  70. ncbi Mesoporous silica as a membrane for ultra-thin implantable direct glucose fuel cells
    Tushar Sharma
    Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712, USA
    Lab Chip 11:2460-5. 2011
    ..involved the use of a surfactant-coated polypropylene membrane (50 μm) with activated carbon (198 μm) electrodes. We demonstrate that a mesoporous silica thin film (270 nm) is capable of replacing the conventional polymer ..
  71. pmc Dissolvable films of silk fibroin for ultrathin conformal bio-integrated electronics
    Dae Hyeong Kim
    Department of Materials Science and Engineering, Beckman Institute for Advanced Science and Technology and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    Nat Mater 9:511-7. 2010
    ..In vivo, neural mapping experiments on feline animal models illustrate one mode of use for this class of technology. These concepts provide new capabilities for implantable and surgical devices...
  72. ncbi Electric and thermal field effects in tissue around radiofrequency electrodes
    Eric R Cosman
    Department of Electrical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    Pain Med 6:405-24. 2005
    ..Finite-element calculation of the fields is performed, and results are compared with ex vivo tissue data. Field predictions are made for continuous and for pulsed RF applications...
  73. ncbi Electrochemical sensor for dopamine based on a novel graphene-molecular imprinted polymers composite recognition element
    Yan Mao
    Engineering Laboratory for Modern Analytical Techniques, c o State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Graduate University of the Chinese Academy of Sciences, Chinese Academy of Sciences, Changchun 130022, Jilin, PR China
    Biosens Bioelectron 28:291-7. 2011
    ..The new DA electrochemical sensor based on GSCR-MIPs composites also exhibited excellent repeatability, which expressed as relative standard deviation (RSD) was about 2.50% for 30 repeated analyses of 20 μM DA...
  74. ncbi A kinetic perspective on extracellular electron transfer by anode-respiring bacteria
    César I Torres
    Center for Environmental Biotechnology, Biodesign Institute at Arizona State University, Tempe, AZ 85287, USA
    FEMS Microbiol Rev 34:3-17. 2010
    ..Thus, a study of the biological components that create a solid conductive matrix is of critical importance for understanding the function of ARB...
  75. ncbi Patient-specific treatment planning of electrochemotherapy: procedure design and possible pitfalls
    Denis Pavliha
    University of Ljubljana, Faculty of Electrical Engineering, Ljubljana, Slovenia
    Bioelectrochemistry 87:265-73. 2012
    ..e. electric field distribution as well as electrodes' position and number) and is suitable for treatment of deep-seated tumors...
  76. ncbi Microtoming coupled to microarray analysis to evaluate the spatial metabolic status of Geobacter sulfurreducens biofilms
    Ashley E Franks
    Department of Microbiology, University of Massachusetts, Amherst, MA, USA
    ISME J 4:509-19. 2010
    ..The microtoming/microarray strategy described here may be useful for evaluating gene expression with depth in a diversity of microbial biofilms...
  77. ncbi A comparison of surface and intramuscular myoelectric signal classification
    Levi J Hargrove
    Institute of Biomedical Engineering, Department of Electrical and Computer Engineering, University of New Brunswick, P O Box 4400, Fredericton, NB E3B 5A3, Canada
    IEEE Trans Biomed Eng 54:847-53. 2007
    ..Impressive classification accuracy (97%) could be achieved by optimally selecting only three channels of surface MES...
  78. ncbi Minimization of cochlear implant stimulus artifact in cortical auditory evoked potentials
    Phillip M Gilley
    School of Behavioral and Brain Sciences, Callier Advanced Hearing Research Center, The University of Texas at Dallas, 1966 Inwood Road, 75235, USA
    Clin Neurophysiol 117:1772-82. 2006
    ..To compare two methods of minimizing cochlear implant artifact in cortical auditory evoked potential (CAEP) recordings...
  79. ncbi Spinal cord stimulation electrode design: a prospective, randomized, controlled trial comparing percutaneous with laminectomy electrodes: part II-clinical outcomes
    Richard B North
    Department of Neurosurgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21287 7881, USA
    Neurosurgery 57:990-6; discussion 990-6. 2005
    ..In a randomized comparison of four-contact percutaneous and four-contact insulated laminectomy electrodes placed at the same level in the dorsal, epidural midline, quantitative measures of stimulator performance ..
  80. ncbi Cell electrophysiology with carbon nanopipettes
    Michael G Schrlau
    Department of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    ACS Nano 3:563-8. 2009
    ..In addition to their superior injection capabilities reported previously, CNPs are capable of multifunctionality, enabling, for example, concurrent intracellular injection and electrical measurements without damaging cells...
  81. ncbi Prioritising guidance cues: directional migration induced by substratum contours and electrical gradients is controlled by a rho/cdc42 switch
    Ann M Rajnicek
    School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK
    Dev Biol 312:448-60. 2007
    ..Our data are consistent with the idea that migrating CECs use a cdc42/rho "switch" to sort vectoral cues, with cdc42 controlling electrotaxis and rho controlling contact guidance...
  82. pmc Hepatic radiofrequency ablation using multiple probes: ex vivo and in vivo comparative studies of monopolar versus multipolar modes
    Jeong Min Lee
    Department of Radiology, and Institute of Radiation Medicine, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    Korean J Radiol 7:106-17. 2006
    We wanted to compare the efficiency of multipolar radiofrequency ablation (RFA) using three perfused-cooled electrodes with multiple overlapping and simultaneous monopolar techniques for creating an ablation zone in ex vivo bovine livers ..
  83. pmc Greater osteoblast proliferation on anodized nanotubular titanium upon electrical stimulation
    Batur Ercan
    Division of Engineering, Brown University, Providence, RI 02912, USA
    Int J Nanomedicine 3:477-85. 2008
    ..Thus, results of this study suggest that coupling the positive influences of electrical stimulation and nanotubular features on anodized titanium may improve osteoblast responses necessary for enhanced orthopedic implant efficacy...
  84. ncbi Deep brain stimulation of the subthalamic nucleus for the treatment of Parkinson's disease
    Alim Louis Benabid
    Department of Neurosurgery and Neurology, University of Grenoble, CHU Albert Michallon, Grenoble, France
    Lancet Neurol 8:67-81. 2009
    ..side-effects created by spread of stimulation to surrounding structures, depending on the precise location of electrodes. Quality of life improves substantially, inducing sudden global changes in patients' lives, often requiring ..
  85. ncbi Temporary gastric electrical stimulation with orally or PEG-placed electrodes in patients with drug refractory gastroparesis
    Srinivasa Ayinala
    Division of Digestive Diseases, University of Mississippi Medical Center, 2500 N State Street, Jackson, MS 39216, USA
    Gastrointest Endosc 61:455-61. 2005
    ..Placement of temporary GES electrodes endoscopically (ENDOstim) or via a PEG (PEGstim) is feasible, thereby allowing rapid assessment and comparison ..
  86. pmc Study of stability of time-domain features for electromyographic pattern recognition
    Dennis Tkach
    Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, 345 E, Superior Street, Suite 1309, Chicago, IL 60611, USA
    J Neuroeng Rehabil 7:21. 2010
    ....
  87. ncbi Increasing the coulombic efficiency of glucose biofuel cell anodes by combination of redox enzymes
    Federico Tasca
    Department of Analytical Chemistry, Lund University, P O Box 124, SE 221 00 Lund, Sweden
    Biosens Bioelectron 25:1710-6. 2010
    ..They do not react directly with oxygen and produce no H(2)O(2). Electrodes were prepared by embedding (i) only AmPDH (in order to study this enzyme separately) and (ii) a mixture of AmPDH ..
  88. ncbi The use of electrochemical impedance spectroscopy for biosensing
    F Lisdat
    Biosystems Technology, Wildau University of Applied Sciences, 15745, Wildau, Germany
    Anal Bioanal Chem 391:1555-67. 2008
    ..Special attention is devoted to the various electrode design and amplification schemes developed for sensitivity enhancement. Electrolyte insulator semiconductor (EIS) structures will be treated separately...
  89. ncbi Double-codified gold nanolabels for enhanced immunoanalysis
    Adriano Ambrosi
    Nanobioelectronics and Biosensors Group, Institut Catala de Nanotecnologia, Barcelona, Catalonia, Spain
    Anal Chem 79:5232-40. 2007
    ..The developed label and method is versatile, offers enhanced performances, and can be easily extended to other protein detection schemes as well as in DNA analysis...
  90. pmc Single trial classification of motor imagination using 6 dry EEG electrodes
    Florin Popescu
    Intelligent Data Analysis Laboratory, Fraunhofer Institute FIRST, Berlin, Germany
    PLoS ONE 2:e637. 2007
    ..BCI requires accurate classification of small amplitude brain signal components in single trials from recordings which can be compromised by currents induced by muscle activity...
  91. pmc Comparison of recordings from microelectrode arrays and single electrodes in the visual cortex
    Ryan C Kelly
    Center for the Neural Basis of Cognition, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    J Neurosci 27:261-4. 2007
  92. ncbi Temporally and spatially coordinated roles for Rho, Rac, Cdc42 and their effectors in growth cone guidance by a physiological electric field
    Ann M Rajnicek
    School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen, Scotland, AB25 2ZD, UK
    J Cell Sci 119:1723-35. 2006
    ..Our results complement studies of growth cone guidance by diffusible chemical gradients and suggest that growth cones might interpret these co-existing guidance cues selectively...
  93. ncbi Novel dry polymer foam electrodes for long-term EEG measurement
    Chin Teng Lin
    Department of Electrical Engineering, Institute of Imaging and Biomedical Photonics and Brain Research Center, National Chiao Tung University, Hsinchu 300, Taiwan
    IEEE Trans Biomed Eng 58:1200-7. 2011
    ..In general, the conventional wet electrodes are most frequently used for EEG measurement...
  94. ncbi Electrode-distance dependent after-effects of transcranial direct and random noise stimulation with extracephalic reference electrodes
    Vera Moliadze
    Department of Clinical Neurophysiology, Georg August University, Robert Koch Strasse 40, Gottingen, Germany
    Clin Neurophysiol 121:2165-71. 2010
    To evaluate the importance of the distance between stimulation electrodes, in various montages, on the ability to induce sustained cortical excitability changes using transcranial direct and random noise stimulation.
  95. ncbi GABAergic modulation of DC stimulation-induced motor cortex excitability shifts in humans
    Michael A Nitsche
    Department of Clinical Neurophysiology, University of Goettingen, Robert Koch Str 40, 37075 Goettingen, Germany
    Eur J Neurosci 19:2720-6. 2004
    ..Because intracortical inhibition and facilitation are not changed in this phase compared with pre-tDCS values, excitability changes originating from remote cortical or subcortical areas could be involved...
  96. ncbi A standardized boundary element method volume conductor model
    Manfred Fuchs
    Neuroscan Laboratories, Lutterothstrasse 28e, D 20255 Hamburg, Germany
    Clin Neurophysiol 113:702-12. 2002
    ..The localization accuracy of the new approach was tested in a comparison with simulated data and with individual BEM models of epileptic spike data from several patients...
  97. ncbi Investigating and exploiting the electrocatalytic properties of hydrogenases
    Kylie A Vincent
    Inorganic Chemistry Laboratory, Department of Chemistry, University of Oxford, South Parks Road, Oxford OX1 3QR, United Kingdom
    Chem Rev 107:4366-413. 2007
  98. ncbi Propagation of interictal epileptiform activity can lead to erroneous source localizations: a 128-channel EEG mapping study
    Goran Lantz
    Functional Brain Mapping Laboratory and dagger Unit of Presurgical Epilepsy Evaluation, Neurology Clinic, University Hospital, Geneva, Switzerland
    J Clin Neurophysiol 20:311-9. 2003
    ..The results illustrate that intraspike propagation has to be considered in source localizations, and they also illustrate the usefulness of spatio-temporal segmentation for visualizing this propagation...
  99. ncbi Epimeric monosaccharide-quinone hybrids on gold electrodes toward the electrochemical probing of specific carbohydrate-protein recognitions
    Xiao Peng He
    Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Road, Shanghai, People s Republic of China
    J Am Chem Soc 133:3649-57. 2011
    ....
  100. ncbi A comparison of redox polymer and enzyme co-immobilization on carbon electrodes to provide membrane-less glucose/O2 enzymatic fuel cells with improved power output and stability
    Saravanan Rengaraj
    School of Chemistry, National University of Ireland Galway, Galway, Ireland
    Biosens Bioelectron 30:294-9. 2011
    Glassy carbon and graphite electrodes modified with films of enzyme and osmium redox polymer, cross linked with poly (ethylene glycol) diglycidyl ether, were used for elaboration of a glucose/O(2) enzymatic fuel cell...
  101. ncbi Recombinantly produced cellobiose dehydrogenase from Corynascus thermophilus for glucose biosensors and biofuel cells
    Wolfgang Harreither
    Food Biotechnology Laboratory, Department of Food Sciences and Technology, BOKU University of Natural Resources and Life Sciences, Vienna, Austria
    Biotechnol J 7:1359-66. 2012
    ..The performance of rCtCDH-modified electrodes demonstrates the suitability for electrochemical studies...

Research Grants87

  1. Wireless At-Risk Infant Monitoring System
    JASON HOLMSTEDT; Fiscal Year: 2012
    ..The Petal Patch achieves high-precision electrode placement that enables the ECG electrodes to be placed at appropriate distances and provide accurate measurements, reducing human error and making it ..
  2. Chronic Electrical Stimulation to Reduce Bladder Hyperreflexia after SCI
    Kenneth J Gustafson; Fiscal Year: 2012
    ..Surface electrodes will be placed on the shaft of the penis to stimulate the GN, and urodynamic studies will be conducted every two ..
  3. Nanoelectrode arrays for study of the molecular mechanisms, triggers, and inhibit
    Peter J Burke; Fiscal Year: 2012
    ..we propose to extend studies that have monitored the action potentials in neurons using an array of parallel electrodes to which the mitochondria are adhered...
  4. Chicago Endothelial Function Study
    Louise C Hawkley; Fiscal Year: 2010
    ..CONSULTANT COSTS EQUIPMENT (Itemize) Tonometric Blood Pressure Monitor SUPPLIES (Itemize by category) EKG electrodes. Filter Paper, Blood Tubes, Chemicals $2,250 Computer, Software $2,500 Nitroglycerine, Urine Bottles, Salivettes,..
  5. Improving ambulatory community access after paralysis
    Rudi Kobetic; Fiscal Year: 2012
    ..will undergo baseline gait evaluation and have an 8-channel implantable pulse generator (IPG) and intramuscular electrodes surgically installed to correct their gait deficit...
  6. CRF and Stress Modulation of Phasic Dopamine Release and Behavior
    MATTHEW J WANAT; Fiscal Year: 2013
    ..Charles Chavkin. Dr. Phillips pioneered voltammetry recordings using chronically implanted electrodes that remain viable for months, and as such provides an excellent environment to perform these experiments...
  7. Transcutaneous vagus nerve stimulation in cerebral ischemia
    Ilknur Ay; Fiscal Year: 2013
    ..Stimulation of the cervical vagus nerve using surgically implanted electrodes (cVNS) is an FDA-approved treatment in some epilepsy and depression patients...
  8. Intra vs. extracortical command signals to restore six dimensional hand movements
    DAWN MARIE TAYLOR; Fiscal Year: 2012
    ..into the brain and can detect the firing activity of many individual neurons, and 2) larger extracortical electrodes that detect the average electrical activity of larger groups of neurons from locations outside the brain...
  9. Biomimetic Microsystem for High Throughput Evaluation of Engineered Nanomaterials
    Robert M Worden; Fiscal Year: 2010
    ..BLM will be deposited on electrodes and exposed to the ENM...
  10. Improved Source Localization for Pediatric Epilepsy
    Damon Hyde; Fiscal Year: 2013
    ..goal is to improve scalp based EEG source localization to a point where the use of highly invasive sub-dural electrodes can be reduced or eliminated...
  11. Advanced technology for neural interfaces based on microstimulation
    DOUGLAS BUCHANAN MCCREERY; Fiscal Year: 2013
    ..charge density in stimulation-induced neuronal injury when the pulse rate is high (250 to 500 pps), and the electrodes'geometric surface areas is in the upper part of the range for microstimulation (2,000 to 4,000 [unreadable]..
  12. GABA-A Receptor Pharmacology of Neural Coding in Hippocampal Place Cells
    TARA MONIQUE STEWART; Fiscal Year: 2012
    ..In this application chronically implanted multi-unit high density electrodes will be used to measure the effects of (1) systemically administered TB21007, an alpha5GABA{A}R preferring ..
  13. Factors that Initiate Arrhythamias in Long QT Syndrome
    Guy Salama; Fiscal Year: 2006
    ..The sympathetic system will be stimulated bilaterally with electrodes inserted in the vertebral column and the parasympathetic system with electrodes on the right and left vagus ..
  14. Electromechanical reshaping of tissue
    Brian Wong; Fiscal Year: 2010
    ..In EMR cartilage is bent into a new shape by a jig, platinum needle electrodes are inserted into regions of increased internal stress, and a small current (<25 mA) is delivered...
  15. Pre-Clinical Development of a Fetal Micropacemaker
    Ramen Chmait; Fiscal Year: 2013
    ..currently no effective treatment options in these cases, and attempts to implant an extra-uterine pacemaker with electrodes on the fetal heart have invariably failed due to lead dislodgement from fetal movement...
  16. Effects of expectation on gustatory cortical activity
    Alfredo Fontanini; Fiscal Year: 2013
    ..experiments proposed will be conducted in awake rats;ensembles of single neurons will be recorded with multiple electrodes implanted in connected areas known to be involved in taste and expectation (GC, orbitofrontal cortex [OFC], ..
  17. Non-invasive neonatal respiration monitor
    ROSE MARIE VISCARDI; Fiscal Year: 2013
    ..However, these electrodes have many disadvantages: (1) They suffer from calibration drift due to depletion of the electrolyte;(2) lack of ..
  18. The Impact of Deep Brain Stimulation on Frontal-Subcortical Emotional Processing
    Joseph S Neimat; Fiscal Year: 2012
    ..made from neurons in the basal ganglia allow us to precisely determine the local physiological anatomy so that electrodes are placed with precision in the required nuclei...
  19. Novel modalities for assessing the cortical tissue-electrode interface
    Jeffrey R Capadona; Fiscal Year: 2010
    ..In order to quench the neurodegenerative inflammatory response to cortical electrodes, the objective of this project is to first develop an improved understanding of the inflammatory cascade, in ..
  20. Fluid transport in inner ear development
    A PHILINE WANGEMANN; Fiscal Year: 2013
    ..sac? This aim will be addressed by measuring the composition of inner ear fluids with ion-selective electrodes. Aim2) what mechanisms mediate fluid secretion? Aim3) what mechanisms mediate fluid absorption? These aims will ..
  21. Functional Anatomic Imaging of CF Patients with Early Lung Disease Using microOCT
    Guillermo J Tearney; Fiscal Year: 2013
    ..In addition, potential difference (PD) electrodes will be integrated within the sheath of the ?OCT catheter, enabling co-localized measurements of CFTR ion ..
  22. The mechanistic basis of non-invasive deep brain stimulation by ultrasound
    MERRITT C MADUKE; Fiscal Year: 2012
    ..Current clinical applications of brain stimulation involve either implanted electrodes (which is limited by the invasive nature of the implantation) or transcranial magnetic stimulation (limited by ..
  23. A MICRO-ELECTRODE STUDY OF OXYGEN-BASED FUNCTIONAL CONNECTIVITY
    Lawrence H Snyder; Fiscal Year: 2012
    ..We will then record simultaneous electrophysiological signals from the same or adjacent electrodes and ask what portion of the electrophysiological spectrum (slow cortical potentials, local field potentials, ..
  24. A Digital Feedback Clamp Instrument for Neurophysiology
    Ying Sun; Fiscal Year: 2011
    ..clamping developed from whole cell voltage clamping, in which measured current is fed back through one of two electrodes in the cell in an amount to keep the voltage across the cell membrane constant, as measured on the second ..
  25. Regulation of conducted hyperpolarization in microvascular endothelial cell tubes
    ERIK JOSEF BEHRINGER; Fiscal Year: 2012
    ..the IKCa/SKCa opener (NS309, 1 5M) or ACh (3 5M) attenuated CHP (to -1 nA current, 500 5m separation between electrodes)...
  26. Electrical Stimulation to Restore Three Dimensional Vestibular Sensation
    Charles C Della Santina; Fiscal Year: 2012
    ..mainly due to spurious electrical stimulation of bystander vestibular nerve branches by inadequately selective electrodes. In this project, we will: (1) characterize the dependence of 3D AVOR eye rotations on stimulus parameters;(2) ..
  27. PHARMACOLOGY AND PHYSIOLOGY OF RETINAL GANGLION CELLS
    Andrew T Ishida; Fiscal Year: 2013
    ..will be used to initiate spikes in RGCs, and elicited spikes will be recorded in the nerve fiber layer with MEA electrodes and in the optic nerve with suction electrodes...
  28. Retraining Spinal Circuits With Robot-Assisted Functional Electrical Stimulation
    Deborah Won; Fiscal Year: 2013
    ..Animals will be implanted with electrodes to record electrical activity from the ankle flexor and extensor muscles (EMG) and to stimulate innervating ..
  29. Peripheral chemoreflex hypersensitivity and periodic breathing in heart failure
    NOAH JUSTIN MARCUS; Fiscal Year: 2013
    ..to assess breathing effort/pattern) and renal sympathetic nerve activity (RSNA) at rest via implanted telemetry electrodes, and acute RSNA and ventilatory responses to activation of the CB and central chemoreflexes via brief exposure ..
  30. Advanced Engineering Development of a Chronic Retinal Implant
    JOHN L contact WYATT; Fiscal Year: 2010
    ..initial design will allow for 200 electrically conducting pins to pass through the case to stimulate almost 200 electrodes, over 3 times as many as any other hermetically sealed design currently available...
  31. New Intramuscular Electrodes for Respiratory Pacing in SCI
    James S Walter; Fiscal Year: 2012
    ..As an alternative to mechanical ventilation, stimulation of the phrenic nerve with electrodes implanted in the diaphragm is gaining acceptance...
  32. Neural Interface and Control Design to Restore Sensation in Amputees
    MATTHEW ANTHONY SCHIEFER; Fiscal Year: 2012
    ..Research Plan and Methodology: Five subjects will be implanted with nerve cuff electrodes around residual nerves in their arm: the median, radial, ulnar, and musculocutaenous nerves...
  33. Mechanisms of Synaptic Integration in Central Neurons
    William J Spain; Fiscal Year: 2012
    ..The methods employ patch pipettes (or sharp electrodes in some experiments) to record from visualized neurons in brain slices...
  34. Basal Ganglia-Thalamic Interactions in Behaving Songbirds During Learning
    JESSE HEYMANN GOLDBERG; Fiscal Year: 2013
    ..Even though current therapies in humans involve the stimulation of electrodes chronically implanted into BG structures, we still do not understand how electrical signals propagate through ..
  35. Basal Ganglia-Thalamic Interactions in Behaving Songbirds During Learning
    JESSE HEYMANN GOLDBERG; Fiscal Year: 2011
    ..Even though current therapies in humans involve the stimulation of electrodes chronically implanted into BG structures, we still do not understand how electrical signals propagate through ..
  36. A device for rapid, painless, bedside muscle evaluation of children
    JOSE LUIS BOHORQUEZ; Fiscal Year: 2012
    ..In EIM, non-detectible, low- intensity, alternating electrical current is applied through two surface electrodes and resulting surface voltages are measured...
  37. Cortical and basal ganglia local field potentials in human movement disorders
    Philip A Starr; Fiscal Year: 2012
    ..Movement disorders patients are studied while undergoing awake placement of DBS electrodes. Epilepsy patients are studied while undergoing inpatient video monitoring...
  38. Trigeminal Nerve Stimulation for Epilepsy
    Christopher DeGiorgio; Fiscal Year: 2012
    ..Before the pivotal trial, there is a need to optimize the electrodes used to minimize skin irritation, a common side effect when used for more than 12 hours per day...
  39. Evaluation of Wire Electrodes to Activate the Expiratory Muscles to Restore Cough
    Anthony F DiMarco; Fiscal Year: 2010
    ..can be electrically activated by spinal cord stimulation, a method which involves the surgical placement of disc electrodes through laminotomy incisions...
  40. Synaptic Mechanisms of Vestibular Efferent Responses
    JOSEPH CHRISTOPHER HOLT; Fiscal Year: 2012
    ..For specific aim 3, sharp-electrodes will be used to record efferent activity and label single efferent fibers in a decerebrate preparation...
  41. Delivery of Channel Rhodopsin for Optogenetic Control of Neurons in the Cochlea
    Daniel J Lee; Fiscal Year: 2013
    ..Specifically, although speech perception has been shown to increase with the number of electrodes, the number of effective channels is diminished by the longitudinal spread of electricity...
  42. The Use of Electropalatography in the Treatment of Apraxia of Speech
    Shannon C Mauszycki; Fiscal Year: 2012
    ..the speaker wearing a pseudopalate, which is a custom made acrylic plate embedded with a varying number of electrodes that fits tightly against the upper palate...
  43. Neonatal EEG Monitor
    Tammy Tsuchida; Fiscal Year: 2012
    ..EEG technology to the point that its signal quality is considered comparable to that obtained with wet electrodes on adult subjects...
  44. Linking Spatial Variations in Shear Stress with Oxidation Stress
    Tzung K Hsiai; Fiscal Year: 2013
    ..in vivo model of EIS measurements using fat-fed NZW rabbits;specifically, microfabrication and deployment of the electrodes for intravascular EIS measurements...
  45. Ultrananocrystalline Diamond Microarray Biosensor for Neurochemical Detection
    Prabhu U Arumugam; Fiscal Year: 2012
    ..The goal is to develop chronically implantable UNCD microarray electrodes for long-term (i.e., months to years) recording of multiple neurochemicals, especially if human compatible...
  46. Multichannel Electrosonic Actuation Microarray for Cell-Based Screening
    JOHN MARK MEACHAM; Fiscal Year: 2010
    ..biological cells through microscopic (of order size of a single cell) nozzles with incorporated electroporation electrodes, thereby opening pores in the cell membrane via combined mechano/electroporation for uptake of nanomaterials...
  47. Thalamic Visual Prosthesis
    John S Pezaris; Fiscal Year: 2013
    ..prosthesis by adapting the output phase of the VR simulation to multichannel stimulators driving multicontact electrodes, and implant them in NHPs...
  48. Antihypertensive Effects of Tetanic Baraoreceptor Input Stimulation
    Xiaorui Tang; Fiscal Year: 2011
    ..Thirteen (10 experimental + 3 control) dogs will be used;every dog will have bilateral CSN electrodes. Aim 1 consists of 3 phases: Baseline (7 days) ->Tetanus (7 days) ->Recovery (7 days)...
  49. Assessment and evaluation of Hill-type muscle models for predicting in vivo force
    Andrew A Biewener; Fiscal Year: 2011
    ..EMG recordings, whether from indwelling electrodes or measured from the skin surface, are frequently used in combination with muscle models to simulate and ..
  50. Wireless Cardiorespiratory Monitor for Neonates
    MICHAEL JOHN SCIARRA; Fiscal Year: 2012
    ..have developed a method for acquiring an infant's heart rate at the abdomen and back without the use of electrodes. This new method has been combined with a previously developed FDA 510K cleared wireless respiratory rate sensor...
  51. Interactions Between the Brain Reward and Pain Systems.
    Conan Kornetsky; Fiscal Year: 2010
    ..The intracerebral implanting of two stimulating electrodes, one in a reward site and one in a nociceptive site allows the determination of the brain stimulation escape ..
  52. Mechanisms of Memory Enhancement by Deep Brain Stimulation in Humans
    Itzhak Fried; Fiscal Year: 2013
    ..The project utilizes a rare opportunity to record the activity of single neurons and LFPs from depth electrodes implanted in patients with intractable epilepsy in order to identify the seizure focus fr potential surgical ..
  53. Biosensing Devices for Cytotoxic and Genotoxic Assessment of Nanomaterials
    Chenzhong Li; Fiscal Year: 2012
    ..technology will allow up to several hundred different individual culture wells containing the detecting electrodes to be fabricated on a single chip...
  54. Parallel Solid-State Electrodes for Turn-Key Intracellular Electrophysiology
    Ari Chaney; Fiscal Year: 2013
    ..Our group invented a new technology which we call "Stealth" or biomimetic electrodes. These electrodes are able to fuse into the cellular membrane, providing a minimally damaging, electrically ..
  55. Biosensing in electrochemically controlled nano-junctions
    Krzysztof Slowinski; Fiscal Year: 2013
    ..we will use the electrical conductivity of the NB modified DNA helix interposed between two closely spaced gold electrodes as an analytical nano-device for the detection of TBP based on sequence-specific binding to DNA...
  56. NIH SBIR Phase I: Development of a Novel Boron-doped Ultrananocrystalline Diamond
    Prabhu U Arumugam; Fiscal Year: 2011
    ..As a proof-of-concept, the electrodes will be used to measure dopamine (the most widely studied neurotransmitter) down to 10 nM physiological ..
  57. A Novel Treatment for Retinal Ischemia
    Mark S Humayun; Fiscal Year: 2013
    ..implantable components consist of electronics to receive power and data, electronic circuitry attached to MEMS electrodes inside oxygen permeable membrane bag for electrolysis, and a refillable saline reservoir to replenish the saline ..
  58. Wireless ECoG Recording for Epilepsy Monitoring
    Stuart F Cogan; Fiscal Year: 2013
    ..The accepted best method for locating the epileptogenic zones is to record seizure activity with subdural electrodes implanted chronically for up to seven days...
  59. Synaptic Regulation of Neurogenesis in the Dentate Gyrus
    Brian E Derrick; Fiscal Year: 2012
    ..To test these hypotheses, we will use adult rats with permanently implanted electrodes in the perforant pathway and dentate gyrus...
  60. AUDITORY MEMORIES AND VOCAL LEARNING
    Frederic E Theunissen; Fiscal Year: 2013
    ..in the anesthetized preparation, both with multi-electrode arrays for extracellular recordings or with glass electrodes for intracellular recordings and immunohistochemical work...
  61. Global cortical dynamics in sleep and general anesthesia
    Eran A Mukamel; Fiscal Year: 2013
    ..Using intracranial recordings, obtained from patients implanted with arrays of electrodes in the course of treatment for epilepsy, this study will provide the first map in humans of the fine-scale ..
  62. Interictal discharge events: from physiological effects to cognitive consequences
    Gabriel Kreiman; Fiscal Year: 2012
    ..D., Ph.D., Loddenkemper, M.D. and Madsen, M.D.). We study patients with intractable epilepsy implanted with electrodes to localize epileptogenic areas for resection...
  63. Bladder Voiding via Pudendal Nerve Block
    KENNETH GUSTAFSON; Fiscal Year: 2009
    ..Nerve cuff electrodes will be placed on the pudendal nerves to allow HF block of the urethral sphincter, and on the sacral roots to ..
  64. Virus Electrodes for Fungal Pathogen Detection
    Gary Fujii; Fiscal Year: 2009
    ..The best candidate viratrode will be selected based in maximal sensitivity and largest signal relative to the control electrode. TAF levels in these fluids will be validated in Dr. Moore's laboratory by HPLC. ..
  65. Novel 3D Catheter Tracking System for Intracardiac Navigation
    DORON HARLEV; Fiscal Year: 2009
    ..have the following aims: (1) Develop a prototype system that would be able to track the 3D location of multiple electrodes within an ex-vivo test chamber...
  66. Electrical Stimulation for Hemiplegic Shoulder Pain
    John Chae; Fiscal Year: 2010
    ..Finally, clinical skill or intensive patient training is required to reliably place electrodes on a daily basis and adjust stimulation parameters to provide optimal and tolerable treatment with minimal ..
  67. Electrodeposited Noble Metal Oxide Neural Electrodes
    Stuart Cogan; Fiscal Year: 2002
    ..noble metal oxides as low-impedance, high-charge injection coatings for neural recording and stimulating electrodes is proposed. The coatings are based on iridium and ruthenium oxides...
  68. CHEMORECEPTOR ACTIVITY OF THE CAROTID BODY
    Carlos Eyzaguirre; Fiscal Year: 1990
    ..Intracellular ion-selective electrodes (liquid membrane type) should help reveal the cytoplasmatic ionic activities at rest and during receptor ..
  69. NORMAL & PATHOLOGICAL ENAMEL MINERALIZATION
    Takaaki Aoba; Fiscal Year: 1993
    ..Analyses of micro volumes of the fluid will be conducted by the use of ion chromatography and micro- electrodes. 2) Identification of the calcium-binding ligands in the fluid...
  70. DEVELOPMENT OF AN IMPLANTABLE EMG MICRO-TELEMETER
    DAVID EDELL; Fiscal Year: 2006
    ..These are most often controlled by electrical signals or ElectroMyoGrams (EMGs) from a pair of skin surface electrodes. The joint being controlled is most commonly selected by tensing both muscles simultaneously which causes the ..
  71. A Continuous Monitor for Arsenic in Drinking Water
    William Dietze; Fiscal Year: 2004
    ..pretreatment system and a novel flow-cell that will use the patented and proven technology of Nano-Band (TM) Electrodes to determine arsenic concentrations at or below 0.2 ppb...
  72. ELECTRODE DESIGN FOR CARDIAC TACHYARRYTHMIA RF ABLATION
    John Webster; Fiscal Year: 2002
    ..This research will improve the electrodes and improve the procedure...
  73. Development of Natural Orifice Translumenal Endoscopic Neurostimulation
    Anthony Ignagni; Fiscal Year: 2007
    ..sclerosis (ALS) patients have been successfully implanted with laparoscopically placed intramuscular diaphragm electrodes to pace and condition the diaphragm...
  74. Integrated EEG/NIR Sensor System for Infants
    Catherine Poulsen; Fiscal Year: 2009
    ..A dense-array of 128 combined opto-electrodes sitting on the surface of the scalp will simultaneously record brain electrical activity (electroencephalography,..
  75. DIRECT BRAIN INTERFACE BASED ON EVENT DETECTION IN ECOG
    SIMON LEVINE; Fiscal Year: 2002
    ..and testing with subjects at the University of Michigan and Henry Ford Hospitals who have implanted electrodes for purposes related to epilepsy surgery...
  76. DIRECT BRAIN INTERFACE BASED ON EVENT DETECTION IN ECOG
    SIMON LEVINE; Fiscal Year: 2005
    ..and testing with subjects at the University of Michigan and Henry Ford Hospitals who have implanted electrodes for purposes related to epilepsy surgery...
  77. Wireless Multichannel Electrocorticogram Recording for Epilepsy Monitoring
    Stuart Cogan; Fiscal Year: 2009
    ..for surgical placement and will avoid the use of the transcranial multiwire cables that connect the recording electrodes to data processing and storage hardware...
  78. Anticonvulsant effects of novel concentric ring electrode electrical stimulation
    WALTER GRANT BESIO; Fiscal Year: 2010
    ..Non-invasive transcutaneous electrical stimulation (TcES) via unique concentric ring electrodes on the scalp surface is proposed as an innovative approach to seizure control...
  79. Breast Cancer Diagnosis by Electrical Impedance Imaging
    JONATHAN NEWELL; Fiscal Year: 2009
    ..Impedance Tomography (EIT), makes images of the interior of the body by applying electrical signals to electrodes applied to the skin...
  80. Implanted Neuroprosthesis for Restoring Arm and Hand Function after Stroke
    Jayme Knutson; Fiscal Year: 2009
    ..The implanted components include a multi- channel stimulator-telemeter, stimulation electrodes, and EMG-recording electrodes. The stimulating electrodes will be implanted on paralyzed upper extremity muscles...
  81. Carbon Nanopipette ElectroProbe in Cell-Electrophysiology Applications
    CHAMIKA WANSAPURA; Fiscal Year: 2009
    ..Conducting films can be patterned on the glass capillary's outer surface to form counter/reference electrodes. These devices can inject chemicals and macromolecules into single cells, extract fluids and specific proteins ..
  82. SPEECH PROCESSORS FOR AUDITORY PROSTHESES
    BLAKE WILSON; Fiscal Year: 2000
    ..conveyed to the remaining auditory nerve fibers and the cochlear nucleus during electrical stimulation with electrodes in the scala tympani and on the surface of the cochlear nucleus...
  83. Wireless Multi-Modal Brain Monitoring
    BRUCE LANNING; Fiscal Year: 2010
    ..is an increasing demand for real-time monitoring of a larger number (>200 channels) and different types of electrodes and modalities to provide adequate spatial and temporal resolution for pathophysiology;a challenge that becomes ..
  84. Multi-electrode Arrays with Non-hermetic Encapsulation for Neural Prostheses
    Stuart F Cogan; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Neural prostheses presently in commercial use employ foil and wire electrodes connected to implantable pulse generators (IPGs) housed in hermetically sealed titanium cans...
  85. Carbon Nanotube Fibers as Implantable Neural Electrodes
    Douglas Adamson; Fiscal Year: 2009
    ..hair-like" fibers, CNF combine unique properties of porous nanostructured scaffolds, conductive microwires and electrodes, permeable microfluidic conduits, and high area supports for bioactive agents and biocatalysts...
  86. ADAPTIVE ELECTRIC CURRENT COMPUTED TOMOGRAPHY SYSTEM
    JONATHAN NEWELL; Fiscal Year: 1990
    ..This system will apply patterns of electric current through an array of electrodes on the surface of a body, and record the voltages that result on those electrodes...
  87. Enhancing Neuroprosthesis Performance with Nerve Cuff Electrodes
    Ronald J Triolo; Fiscal Year: 2010
    ..We will accomplish this by developing and deploying new nerve cuff electrodes designed specifically for the compound femoral and sciatic nerves...