occult blood

Summary

Summary: Chemical, spectroscopic, or microscopic detection of extremely small amounts of blood.

Top Publications

  1. ncbi Identification of colorectal adenomas by a quantitative immunochemical faecal occult blood screening test depends on adenoma characteristics, development threshold used and number of tests performed
    P Rozen
    Gastroenterology Department, Rabin Medical Center, Beilinson Hospital, Petach Tikva
    Aliment Pharmacol Ther 29:906-17. 2009
  2. ncbi Cochrane systematic review of colorectal cancer screening using the fecal occult blood test (hemoccult): an update
    Paul Hewitson
    Department of Primary Health Care, University of Oxford, Oxford, United Kingdom
    Am J Gastroenterol 103:1541-9. 2008
  3. ncbi Screening for colorectal cancer: randomised trial comparing guaiac-based and immunochemical faecal occult blood testing and flexible sigmoidoscopy
    L Hol
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre Rotterdam, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Gut 59:62-8. 2010
  4. ncbi Asia Pacific consensus recommendations for colorectal cancer screening
    J J Y Sung
    The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong
    Gut 57:1166-76. 2008
  5. ncbi The effect of fecal occult-blood screening on the incidence of colorectal cancer
    J S Mandel
    Exponent, Menlo Park, Calif 94025, USA
    N Engl J Med 343:1603-7. 2000
  6. ncbi Inequalities in participation in an organized national colorectal cancer screening programme: results from the first 2.6 million invitations in England
    Christian von Wagner
    Health Behaviour Research Centre, Department of Epidemiology and Public Health, University College London, London, Greater London, UK
    Int J Epidemiol 40:712-8. 2011
  7. pmc Demographic, social cognitive and social ecological predictors of intention and participation in screening for colorectal cancer
    Tess A Gregory
    School of Psychology, University of Adelaide, Adelaide 5000, Australia
    BMC Public Health 11:38. 2011
  8. ncbi Results from the first three rounds of the Scottish demonstration pilot of FOBT screening for colorectal cancer
    R J C Steele
    Department of Surgery, University of Dundee, Dundee, UK
    Gut 58:530-5. 2009
  9. ncbi Colonoscopic screening of average-risk women for colorectal neoplasia
    Philip Schoenfeld
    Division of Gastroenterology, University of Michigan School of Medicine and Veterans Affairs Center for Excellence in Health Services Research, Ann Arbor 48105, USA
    N Engl J Med 352:2061-8. 2005
  10. pmc Screening for colorectal cancer: random comparison of guaiac and immunochemical faecal occult blood testing at different cut-off levels
    L Hol
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands
    Br J Cancer 100:1103-10. 2009

Detail Information

Publications343 found, 100 shown here

  1. ncbi Identification of colorectal adenomas by a quantitative immunochemical faecal occult blood screening test depends on adenoma characteristics, development threshold used and number of tests performed
    P Rozen
    Gastroenterology Department, Rabin Medical Center, Beilinson Hospital, Petach Tikva
    Aliment Pharmacol Ther 29:906-17. 2009
    Faecal occult blood tests (FOBT) are faulted by low sensitivity for advanced adenomatous polyps (AAP). Quantified, immunochemical, haemoglobin (Hb)-specific immunochemical FOBT (I-FOBT) measurements are now used for colorectal screening.
  2. ncbi Cochrane systematic review of colorectal cancer screening using the fecal occult blood test (hemoccult): an update
    Paul Hewitson
    Department of Primary Health Care, University of Oxford, Oxford, United Kingdom
    Am J Gastroenterol 103:1541-9. 2008
    ..of the systematic review was to update previous research to determine whether screening for CRC using the fecal occult blood test (FOBT) reduces CRC mortality and to consider the benefits, harms, and potential consequences of screening.
  3. ncbi Screening for colorectal cancer: randomised trial comparing guaiac-based and immunochemical faecal occult blood testing and flexible sigmoidoscopy
    L Hol
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre Rotterdam, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Gut 59:62-8. 2010
    ..We conducted a randomised trial comparing participation and detection rates (DR) per screenee of guaiac-based faecal occult blood test (gFOBT), immunochemical FOBT (FIT), and flexible sigmoidoscopy (FS) for CRC screening.
  4. ncbi Asia Pacific consensus recommendations for colorectal cancer screening
    J J Y Sung
    The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong
    Gut 57:1166-76. 2008
    ..Male gender, smoking, obesity and family history are risk factors for colorectal neoplasia. Faecal occult blood test (FOBT, guaiac-based and immunochemical tests), flexible sigmoidoscopy and colonoscopy are recommended for ..
  5. ncbi The effect of fecal occult-blood screening on the incidence of colorectal cancer
    J S Mandel
    Exponent, Menlo Park, Calif 94025, USA
    N Engl J Med 343:1603-7. 2000
    Both annual testing for fecal occult blood and biennial testing significantly reduce mortality from colorectal cancer...
  6. ncbi Inequalities in participation in an organized national colorectal cancer screening programme: results from the first 2.6 million invitations in England
    Christian von Wagner
    Health Behaviour Research Centre, Department of Epidemiology and Public Health, University College London, London, Greater London, UK
    Int J Epidemiol 40:712-8. 2011
    ..colorectal cancer screening programme was initiated in England in 2006 offering biennial faecal occult blood testing (FOBT) to adults aged 60-69 years...
  7. pmc Demographic, social cognitive and social ecological predictors of intention and participation in screening for colorectal cancer
    Tess A Gregory
    School of Psychology, University of Adelaide, Adelaide 5000, Australia
    BMC Public Health 11:38. 2011
    ..The aim of this study was to compare the social cognitive and social ecological predictors of intention to screen with predictors of participation...
  8. ncbi Results from the first three rounds of the Scottish demonstration pilot of FOBT screening for colorectal cancer
    R J C Steele
    Department of Surgery, University of Dundee, Dundee, UK
    Gut 58:530-5. 2009
    To assess the effects of the first three rounds of a pilot colorectal screening programme based on guaiac faecal occult blood testing (gFOBT) and their implications for a national population-based programme.
  9. ncbi Colonoscopic screening of average-risk women for colorectal neoplasia
    Philip Schoenfeld
    Division of Gastroenterology, University of Michigan School of Medicine and Veterans Affairs Center for Excellence in Health Services Research, Ann Arbor 48105, USA
    N Engl J Med 352:2061-8. 2005
    ..In a tandem study, we examined the yield of screening colonoscopy in women...
  10. pmc Screening for colorectal cancer: random comparison of guaiac and immunochemical faecal occult blood testing at different cut-off levels
    L Hol
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands
    Br J Cancer 100:1103-10. 2009
    Immunochemical faecal occult blood testing (FIT) provides quantitative test results, which allows optimisation of the cut-off value for follow-up colonoscopy...
  11. ncbi Monitoring disease activity by stool analyses: from occult blood to molecular markers of intestinal inflammation and damage
    D Foell
    Department of Pediatrics, University of Muenster, Albert Schweitzer Str 33, D 48149 Muenster, Germany
    Gut 58:859-68. 2009
    ..We review the biology of this novel group of molecules which can be used as surrogate markers directly linked to the molecular mechanisms of gut inflammation...
  12. ncbi A comparison of the immunochemical fecal occult blood test and total colonoscopy in the asymptomatic population
    Tamiya Morikawa
    Department of Medicine and Medical Science, Okayama University Graduate School of Medicine and Dentistry, Japan
    Gastroenterology 129:422-8. 2005
    The fecal occult blood test (FOBT) is recommended as a screening test for colorectal cancer, but there are few reliable studies on the accuracy of immunochemical FOBT...
  13. pmc Comparison and combination of blood-based inflammatory markers with faecal occult blood tests for non-invasive colorectal cancer screening
    S Tao
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Centre, Heidelberg, Germany
    Br J Cancer 106:1424-30. 2012
    Faecal occult blood tests (FOBTs) are widely used for colorectal cancer (CRC) screening. Blood-based inflammatory markers have been suggested as alternative or supplementary non-invasive CRC screening tests.
  14. ncbi Comparing participation rates between immunochemical and guaiac faecal occult blood tests: a systematic review and meta-analysis
    Gemma Vart
    Department of Epidemiology and Public Health, University College London, London, WC1E 6BT, UK
    Prev Med 55:87-92. 2012
    Biennial screening with faecal occult blood tests (FOBts) has been found to reduce colorectal cancer mortality...
  15. ncbi Colonoscopy and fecal occult blood test use in Germany: results from a large insurance-based cohort
    C Stock
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Endoscopy 43:771-81. 2011
    Colonoscopy and guaiac-based fecal occult blood tests (FOBT) are recommended and offered for colorectal cancer (CRC) screening in Germany. We aimed to explore their utilization in a large insurance-based cohort.
  16. ncbi What affects the uptake of screening for bowel cancer using a faecal occult blood test (FOBt): a qualitative study
    Alison Chapple
    Department of Primary Health Care, University of Oxford, Oxford, UK
    Soc Sci Med 66:2425-35. 2008
    ..The UK National Health Service Bowel Cancer Screening Programme (NHS BCSP), using the Faecal Occult Blood test (FOBt), is being introduced over three years in the UK, but in some areas uptake is disappointing...
  17. pmc The impact of population-based faecal occult blood test screening on colorectal cancer mortality: a matched cohort study
    G Libby
    Scottish Bowel Screening Research Unit, Kings Cross, Clepington Road, Dundee DD3 8EA, UK
    Br J Cancer 107:255-9. 2012
    Randomised trials show reduced colorectal cancer (CRC) mortality with faecal occult blood testing (FOBT). This outcome is now examined in a routine, population-based, screening programme.
  18. pmc Effect of repeated invitations on uptake of colorectal cancer screening using faecal occult blood testing: analysis of prevalence and incidence screening
    R J C Steele
    Department of Surgery, University of Dundee, UK
    BMJ 341:c5531. 2010
    To analyse the effects of prevalence and incidence screening on uptake and detection of cancer in an ongoing, dynamic programme for colorectal screening using faecal occult blood testing.
  19. ncbi Effect of gender, age and deprivation on key performance indicators in a FOBT-based colorectal screening programme
    R J C Steele
    Department of Surgery, University of Dundee and Scottish Bowel Screening Centre, King s Cross Hospital, Dundee, UK
    J Med Screen 17:68-74. 2010
    ..To assess the effect of gender, age and deprivation on key performance indicators in a colorectal cancer screening programme...
  20. ncbi Colorectal cancer mortality: effectiveness of biennial screening for fecal occult blood
    J S Mandel
    Division of Environmental and Occupational Health, School of Public Health, University of Minnesota, Minneapolis 55455, USA
    J Natl Cancer Inst 91:434-7. 1999
    In 1993, a randomized controlled trial in Minnesota showed, after 13 years of follow-up, that annual fecal occult blood testing was effective in reducing colorectal cancer mortality by at least 33%. Biennial screening (i.e...
  21. pmc Stool DNA and occult blood testing for screen detection of colorectal neoplasia
    David A Ahlquist
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Ann Intern Med 149:441-50, W81. 2008
    ..Stool DNA testing is a new approach to colorectal cancer detection. Few data are available from the screening setting...
  22. ncbi Diagnostic accuracy of faecal occult blood tests used in screening for colorectal cancer: a systematic review
    J A Burch
    Centre for Reviews and Dissemination CRD, University of York, York YO10 5DD, UK
    J Med Screen 14:132-7. 2007
    To determine the accuracy of guaiac and immunochemical faecal occult blood tests (FOBTs) for the detection of colorectal cancer in an average-risk screening population.
  23. ncbi Interval cancers in a FOBT-based colorectal cancer population screening programme: implications for stage, gender and tumour site
    R J C Steele
    Department of Surgery, University of Dundee, Dundee, UK
    Gut 61:576-81. 2012
    Between 2000 and 2007, a demonstration pilot of biennial guaiac faecal occult blood test (GFOBT) screening was carried out in Scotland.
  24. ncbi Cost-effectiveness of mass screening for colorectal cancer: choice of fecal occult blood test and screening strategy
    Iradj Sobhani
    Gastroenterology Unit, Albert Chenevier Henri Mondor Hospital, Assistance Publique Hopitaux de Paris, Paris, France
    Dis Colon Rectum 54:876-86. 2011
    ..This gives high public health priority to mass screening using a noninvasive, fecal occult blood test of asymptomatic individuals...
  25. ncbi Cost evaluation in a colorectal cancer screening programme by faecal occult blood test in the District of Florence
    Grazia Grazzini
    ISPO Cancer Prevention and Research Institute Florence, Istituto Tumori Toscano, Viale A Volta 171, 50131 Firenze, Italy
    J Med Screen 15:175-81. 2008
    To evaluate the direct costs of first and repeat colorectal cancer screening by immunochemical faecal occult blood testing (I-FOBT).
  26. pmc Use of fecal occult blood tests as epidemiologic indicators of morbidity associated with intestinal schistosomiasis during preventive chemotherapy in young children
    Martha Betson
    Disease Control Strategy Group, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
    Am J Trop Med Hyg 87:694-700. 2012
    ..We investigated whether fecal occult blood (FOB) point-of-care tests could be used to assess intestinal pathology over a 12-month period in a cohort of ..
  27. ncbi Pre-notification increases uptake of colorectal cancer screening in all demographic groups: a randomized controlled trial
    Gillian Libby
    Scottish Bowel Screening Centre, Kings Cross, Clepington Road, Dundee DD3 8EA
    J Med Screen 18:24-9. 2011
    ..To assess whether pre-notification is effective in increasing uptake of colorectal cancer screening for all demographic groups...
  28. ncbi Validity of self-reported colorectal cancer screening behavior
    M Baier
    American Medical Center Cancer Research Center, Lakewood, Colorado 80214, USA
    Cancer Epidemiol Biomarkers Prev 9:229-32. 2000
    ..Cases who had received a fecal occult blood test (FOBT), flexible sigmoidoscopy, and/or colonoscopy, and controls who had no record of colorectal screening ..
  29. ncbi Responses to procedural information about colorectal cancer screening using faecal occult blood testing: the role of consideration of future consequences
    Christian von Wagner
    Cancer Research UK, Health Behaviour Research Centre, Department of Epidemiology and Public Health, UCL, London, UK
    Health Expect 15:176-86. 2012
    ..AIMS AND RESEARCH QUESTIONS: To monitor the impact of providing information about CRC screening via faecal occult blood testing (FOBt) on intentions to participate...
  30. ncbi Comparison of guaiac-based and quantitative immunochemical fecal occult blood testing in a population at average risk undergoing colorectal cancer screening
    Dong Il Park
    Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
    Am J Gastroenterol 105:2017-25. 2010
    Although some studies have shown that the quantitative, immunochemical fecal occult blood test (FOBT) (qFIT) has better performance characteristics than the standard guaiac-based FOBT (GT) for identifying advanced colorectal neoplasia (..
  31. ncbi Measures for ascertaining use of colorectal cancer screening in behavioral, health services, and epidemiologic research
    Sally W Vernon
    Cancer Epidemiol Biomarkers Prev 13:898-905. 2004
  32. pmc Physician and patient factors associated with ordering a colon evaluation after a positive fecal occult blood test
    Barbara Turner
    Division of General Internal Medicine BT, University of Pennsylvania, Philadelphia, PA, USA
    J Gen Intern Med 18:357-63. 2003
    Successful colorectal cancer screening relies in part on physicians ordering a complete diagnostic evaluation of the colon (CDE) with colonoscopy or barium enema plus sigmoidoscopy after a positive screening fecal occult blood test (FOBT).
  33. ncbi Interval fecal immunochemical testing in a colonoscopic surveillance program speeds detection of colorectal neoplasia
    Joanne M Lane
    Flinders Centre for Cancer Prevention and Control, Flinders University of South Australia, Bedford Park Adelaide, South Australia
    Gastroenterology 139:1918-26. 2010
    ..We investigated whether giving fecal immunochemical tests (FITs) for hemoglobin between surveillance colonoscopies resulted in earlier detection of neoplasia...
  34. pmc Organizational factors and the cancer screening process
    Rebecca Anhang Price
    SAIC Frederick, Inc, Applied Cancer Screening Research Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, 6130 Executive Blvd, EPN 4103A, Rockville, MD 20852, USA
    J Natl Cancer Inst Monogr 2010:38-57. 2010
    ....
  35. ncbi Colonoscopy quality measures: experience from the NHS Bowel Cancer Screening Programme
    Thomas J W Lee
    University Hospital of North Tees, Stockton on Tees, UK
    Gut 61:1050-7. 2012
    ..The NHS Bowel Cancer Screening Programme (BCSP) offers biennial faecal occult blood (FOB) testing to 60-74 year olds and colonoscopy to those with positive FOB tests...
  36. ncbi Quantitative immunochemical fecal occult blood testing for colorectal adenoma detection: evaluation in the target population of screening and comparison with qualitative tests
    Ulrike Haug
    German Cancer Research Center, Heidelberg, Germany
    Am J Gastroenterol 105:682-90. 2010
    Quantitative and qualitative immunochemical fecal occult blood tests (FOBTs) have been proposed for noninvasive colorectal cancer screening, but comparative evaluation is lacking...
  37. pmc Offering annual fecal occult blood tests at annual flu shot clinics increases colorectal cancer screening rates
    Michael B Potter
    Department of Family and Community Medicine, University of California San Francisco, San Francisco, California 94143, USA
    Ann Fam Med 7:17-23. 2009
    We wanted to determine whether providing home fecal occult blood test (FOBT) kits to eligible patients during influenza inoculation (flu shot) clinics can contribute to higher colorectal cancer screening (CRCS) rates.
  38. pmc Primary care, economic barriers to health care, and use of colorectal cancer screening tests among Medicare enrollees over time
    Chyke A Doubeni
    Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Ann Fam Med 8:299-307. 2010
    ..The objective of this study was to examine the impact of primary care and economic barriers to health care on CRC testing relative to the 2001 Medicare expansion of screening coverage...
  39. pmc Socioeconomic and racial patterns of colorectal cancer screening among Medicare enrollees in 2000 to 2005
    Chyke A Doubeni
    Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Cancer Epidemiol Biomarkers Prev 18:2170-5. 2009
    ..Therefore, we examined patterns of colorectal cancer screening and associations with race-ethnicity, education, and income over time...
  40. pmc Improving fecal occult blood testing compliance using a mailed educational reminder
    Jeffrey K Lee
    Department of Medicine, VA San Diego Healthcare System and University of California, San Diego, CA 92161, USA
    J Gen Intern Med 24:1192-7. 2009
    ..Randomized controlled trials have shown that annual screening fecal occult blood testing (FOBT) reduces CRC mortality and incidence. However, patient compliance with FOBT is low.
  41. pmc Data and trends in cancer screening in the United States: results from the 2005 National Health Interview Survey
    Judith Swan
    Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland, USA
    Cancer 116:4872-81. 2010
    ..We also examine trends from 1992 through 2005 to determine whether differences in screening use are increasing, staying the same, or decreasing...
  42. pmc Performance measures in three rounds of the English bowel cancer screening pilot
    S M Moss
    Cancer Screening Evaluation Unit, Section of Epidemiology, Institute of Cancer Research, SRD Building, Cotswold Road, Sutton, Surrey SM2 5NG, UK
    Gut 61:101-7. 2012
    To compare performance measures across all three rounds of the English bowel cancer screening faecal occult blood test pilot and their relation to social deprivation and ethnicity.
  43. pmc A randomised study of screening for colorectal cancer using faecal occult blood testing: results after 13 years and seven biennial screening rounds
    O D Jørgensen
    Department of Surgical Gastroenterology, Odense University Hospital, Denmark
    Gut 50:29-32. 2002
    Three randomised trials have demonstrated reduction in mortality from colorectal cancer (CRC) by repeated screening with faecal occult blood tests, including the trial presented here, which is the only one still in progress.
  44. pmc Randomized controlled trial of the impact of intensive patient education on compliance with fecal occult blood testing
    Charlene L Stokamer
    Department of Patient Services Nursing, VA New York Harbor Healthcare System, New York, NY 10010, USA
    J Gen Intern Med 20:278-82. 2005
    Randomized controlled trials have demonstrated that fecal occult blood testing (FOBT) reduces colorectal cancer (CRC) mortality. However, patient compliance with FOBT is low and this is one of the major barriers to CRC screening.
  45. ncbi Participation in screening for colorectal cancer based on a faecal occult blood test is improved by endorsement by the primary care practitioner
    S R Cole
    Department of Medicine, Flinders University and Bowel Health Service, Repatriation General Hospital Daw Park, South Australia
    J Med Screen 9:147-52. 2002
    To investigate the influence of general practitioner (GP) endorsement on participation in screening for colorectal cancer based on a faecal occult blood test (FOBT).
  46. ncbi Comparison of immunochemical and guaiac-based fecal occult blood test in screening and surveillance for advanced colorectal neoplasms: a meta-analysis
    Ming Ming Zhu
    Department of Gastroenterology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Institute of Digestive Disease, Shanghai, China
    J Dig Dis 11:148-60. 2010
    To systematically evaluate whether immunochemical fecal occult blood tests (iFOBT) could improve clinical performance and test accuracy in screening and surveillance for advanced colorectal neoplasms.
  47. ncbi Colorectal cancer screening knowledge, attitudes, and beliefs among veterans: does literacy make a difference?
    Nancy C Dolan
    Midwest Center for Health Services and Policy Research, VA Chicago Healthcare System, Department of Medicine, Feinberg School of Medicine, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA
    J Clin Oncol 22:2617-22. 2004
    ..To evaluate whether lower literacy is associated with poorer knowledge and more negative attitudes and beliefs toward colorectal cancer screening among veterans without recent colorectal cancer screening...
  48. ncbi American Cancer Society guidelines for the early detection of cancer
    Robert A Smith
    Cancer Control Department, American Cancer Society, Atlanta, GA, USA
    CA Cancer J Clin 52:8-22. 2002
    ....
  49. ncbi Comparative evaluation of immunochemical fecal occult blood tests for colorectal adenoma detection
    Sabrina Hundt
    The German Cancer Research Center, Heidelberg, Germany
    Ann Intern Med 150:162-9. 2009
    Different immunochemical fecal occult blood tests (FOBTs) have been proposed for noninvasive colorectal cancer screening...
  50. ncbi Which colon cancer screening test? A comparison of costs, effectiveness, and compliance
    S Vijan
    The Veterans Affairs Center for Practice Management and Outcomes Research, Ann Arbor, Michigan 48113 0170, USA
    Am J Med 111:593-601. 2001
    ..However, colonoscopy is expensive compared with other screening modalities, such as fecal occult blood testing and flexible sigmoidoscopy...
  51. ncbi Comparison of CT colonography, colonoscopy, sigmoidoscopy and faecal occult blood tests for the detection of advanced adenoma in an average risk population
    A Graser
    Department of Clinical Radiology, University of Munich, Klinikum Grosshadern, Munich, Germany
    Gut 58:241-8. 2009
    ..different screening tests in parallel for the detection of advanced colonic neoplasia: CT colonography (CTC), colonoscopy (OC), flexible sigmoidoscopy (FS), faecal immunochemical stool testing (FIT) and faecal occult blood testing (FOBT).
  52. pmc Value of symptoms and additional diagnostic tests for colorectal cancer in primary care: systematic review and meta-analysis
    Petra Jellema
    Department of General Practice, EMGO Institute for Health and Care Research, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, Netherlands
    BMJ 340:c1269. 2010
    ..To summarise available evidence on diagnostic tests that might help primary care physicians to identify patients with an increased risk for colorectal cancer among those consulting for non-acute lower abdominal symptoms...
  53. pmc Inequalities in colorectal cancer screening participation in the first round of the national screening programme in England
    C von Wagner
    Department of Epidemiology and Public Health, Cancer Research UK Health Behaviour Research Centre, University College London, Gower Street, London, UK
    Br J Cancer 101:S60-3. 2009
    Introduction of organised, population-based, colorectal cancer screening in the United Kingdom using the faecal occult blood test (FOBT) has the potential to reduce overall colorectal cancer mortality...
  54. ncbi Barriers to colorectal cancer screening among Medicare consumers
    Carrie N Klabunde
    Health Services and Economics Branch, Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland, USA
    Am J Prev Med 30:313-9. 2006
    ..Few studies have examined lack of physician recommendation and other reasons for under-utilization of colorectal cancer (CRC) screening in the Medicare population...
  55. pmc Long-term outcomes following positive fecal occult blood test results in older adults: benefits and burdens
    Christine E Kistler
    Department of Family Medicine, University of North Carolina at Chapel Hill, 27599 7595, USA
    Arch Intern Med 171:1344-51. 2011
    In the United States, older adults have low rates of follow-up colonoscopy after a positive fecal occult blood test (FOBT) result. The long-term outcomes of these real world practices and their associated benefits and burdens are unknown.
  56. ncbi Longitudinal adherence to fecal occult blood testing impacts colorectal cancer screening quality
    Ziad F Gellad
    Center for Health Services Research in Primary Care, Department of Veterans Affairs Medical Center, Durham, North Carolina, USA
    Am J Gastroenterol 106:1125-34. 2011
    ..Our goal was to evaluate the adherence to repeated yearly fecal occult blood tests (FOBTs) in order to better understand the extent to which longitudinal adherence may impact screening ..
  57. ncbi Effectiveness of the salivary occult blood test as a screening method for periodontal status
    Yoshihiro Shimazaki
    Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth, and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Japan
    J Periodontol 82:581-7. 2011
    ..This study examines the effectiveness of a novel salivary occult blood test (SOBT) as a screening method for periodontal status.
  58. ncbi Obstacles to colorectal screening in general practice: a qualitative study of GPs and patients
    Isabelle Aubin-Auger
    Département de médecine générale, Denis Diderot University Paris 7, 16 rue Henri, Huchard 75018, Paris, France
    Fam Pract 28:670-6. 2011
    The faecal occult blood test (FOBT) has proven efficiency at screening populations for an average risk of colorectal cancer. Mortality related to this cancer decreases by 15-18% among adults, 50-74 years old, tested every 2 years...
  59. pmc Cost-effectiveness of colorectal cancer screening - an overview
    Iris Lansdorp-Vogelaar
    Department of Public Health, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Best Pract Res Clin Gastroenterol 24:439-49. 2010
    ..There is consensus that the new technologies of stool DNA testing, computed tomographic colonography and capsule endoscopy are not yet cost-effective compared with the established CRC screening tests...
  60. ncbi Superior diagnostic performance of faecal immunochemical tests for haemoglobin in a head-to-head comparison with guaiac based faecal occult blood test among 2235 participants of screening colonoscopy
    Hermann Brenner
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Im Neuenheimer Feld, 69120 Heidelberg, Germany
    Eur J Cancer 49:3049-54. 2013
    ..immunochemical tests (FITs) for haemoglobin offer a number of advantages over traditional guaiac based faecal occult blood tests (gFOBTs)...
  61. pmc Socioeconomic variation in uptake of colonoscopy following a positive faecal occult blood test result: a retrospective analysis of the NHS Bowel Cancer Screening Programme
    S Morris
    Department of Applied Health Research, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Br J Cancer 107:765-71. 2012
    ..The Bowel Cancer Screening Programme (BCSP) in England screens with the Faecal Occult Blood test (FOBt), followed by colonoscopy for individuals with a positive test result...
  62. ncbi Lower risk of advanced neoplasia among patients with a previous negative result from a fecal test for colorectal cancer
    Maaike J Denters
    Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, The Netherlands
    Gastroenterology 142:497-504. 2012
    Consecutive rounds of fecal occult blood tests (FOBTs) are used to screen for colorectal cancer (CRC); they detect precursor lesions and early-stage disease...
  63. ncbi Immunochemical fecal occult blood testing is equally sensitive for proximal and distal advanced neoplasia
    T R de Wijkerslooth
    Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands
    Am J Gastroenterol 107:1570-8. 2012
    ..Fecal immunochemical testing (FIT) is increasingly used for colorectal cancer (CRC) screening. We aimed to estimate its diagnostic accuracy in invitational population screening measured against colonoscopy...
  64. ncbi Direct mailing of faecal occult blood tests for colorectal cancer screening: a randomized population study from Central Italy
    Paolo Giorgi Rossi
    Laziosanità Agency for Public Health, Lazio Region, Rome
    J Med Screen 18:121-7. 2011
    Sending faecal occult blood tests (FOBT) by mail has been proposed both as a method to increase participation and a way to reduce staff costs in colorectal cancer screening.
  65. ncbi Evaluation and comparison of an immunochemical and a guaiac faecal occult blood screening test for colorectal neoplasia
    P Rozen
    Department of Gastroenterology, Tel Aviv Medical Center, Israel
    Eur J Cancer Prev 4:475-81. 1995
    Guaiac tests for faecal occult blood are used for colorectal neoplasia screening. Specificity may be improved by using an immunochemical test for human blood...
  66. ncbi Experience with a two-tier reflex gFOBT/FIT strategy in a national bowel screening programme
    Callum G Fraser
    Centre for Research into Cancer Prevention and Screening, University of Dundee Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland
    J Med Screen 19:8-13. 2012
    To evaluate a two-tier reflex guaiac-based faecal occult blood test (gFOBT)/faecal immunochemical test (FIT) algorithm in screening for colorectal cancer.
  67. ncbi Nottingham trial of faecal occult blood testing for colorectal cancer: a 20-year follow-up
    J H Scholefield
    Department of GI Surgery, University Hospital, Nottingham, UK
    Gut 61:1036-40. 2012
    Three large randomised trials have shown that screening for colorectal cancer (CRC) using the faecal occult blood test (FOBt) can reduce the mortality from this disease...
  68. ncbi Fecal occult blood testing when colonoscopy capacity is limited
    Janneke A Wilschut
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    J Natl Cancer Inst 103:1741-51. 2011
    Fecal occult blood testing (FOBT) can be adapted to a limited colonoscopy capacity by narrowing the age range or extending the screening interval, by using a more specific test or hemoglobin cutoff level for referral to colonoscopy, and ..
  69. ncbi Outcomes and cost evaluation of the first two rounds of a colorectal cancer screening program based on immunochemical fecal occult blood test in northern Italy
    F Parente
    Gastrointestinal Unit, A Manzoni Hospital, Lecco, Italy
    Endoscopy 45:27-34. 2013
    ..The aim of the current study were to assess the outcomes and costs of the first two biennial rounds of a population-based CRC screening program using the immunochemical fecal occult blood test (i-FOBT) in a northern Italian province.
  70. ncbi A population-based comparison of immunochemical fecal occult blood tests for colorectal cancer screening
    Thibaut Raginel
    Centre Hospitalier Universitaire CHU de Caen, Caen, France Normandie University, Caen, France
    Gastroenterology 144:918-25. 2013
    ..Quantitative fecal immunochemical tests (FITs) identify individuals with colorectal cancer with greater levels of accuracy than guaiac tests. We compared the performances of 2 FITs in a population undergoing screening for colorectal cancer...
  71. ncbi Improving participation in colorectal cancer screening: targets for action
    Julien Le Breton
    Université Paris Est UPEC, Faculte de Medecine, Department of General Practice, Creteil, F 94000, France
    Prev Med 55:488-92. 2012
    ....
  72. ncbi Is fecal occult blood testing more sensitive for left- versus right-sided colorectal neoplasia? A systematic literature review
    Ulrike Haug
    Division of Preventive Oncology, National Center for Tumor Diseases German Cancer Research Center DKFZ, Im Neuenheimer Feld 460, 69120 Heidelberg, Germany
    Expert Rev Mol Diagn 11:605-16. 2011
    ..question whether the sensitivity of the most common noninvasive screening tool for colorectal cancer, fecal occult blood testing (FOBT), also differs for left- versus right-sided neoplasia...
  73. ncbi Reliability and validity of a questionnaire to measure colorectal cancer screening behaviors: does mode of survey administration matter?
    Sally W Vernon
    University of Texas Houston School of Public Health, Division of Health Promotion and Behavioral Sciences, Houston, TX 77030, USA
    Cancer Epidemiol Biomarkers Prev 17:758-67. 2008
    ..We evaluated test-retest reliability and validity of self-report of the fecal occult blood test (FOBT), sigmoidoscopy (SIG), colonoscopy (COL), and barium enema (BE) using the National Cancer Institute ..
  74. ncbi The view from two sides: a qualitative study of community and medical perspectives on screening for colorectal cancer using FOBT
    Alexandra M Clavarino
    School of Population Health, University of Queensland, Herston, QLD, Australia
    Prev Med 39:482-90. 2004
    Population-wide screening for people at average risk of colorectal cancer (CRC) by faecal occult blood test (FOBT) is under consideration in Australia.
  75. pmc Performance of the immunochemical fecal occult blood test in predicting lesions in the lower gastrointestinal tract
    Tsung Hsien Chiang
    Department of Internal Medicine, Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan
    CMAJ 183:1474-81. 2011
    Previous studies have suggested that the immunochemical fecal occult blood test has superior specificity for detecting bleeding in the lower gastrointestinal tract even if bleeding occurs in the upper tract...
  76. ncbi Quantitative colonoscopic evaluation of relative efficiencies of an immunochemical faecal occult blood test and a sensitive guaiac test for detecting significant colorectal neoplasms
    P Rozen
    Gastroenterology Department, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Israel
    Aliment Pharmacol Ther 29:450-7. 2009
    The guaiac faecal occult blood test (G-FOBT), HemoccultSENSA, is sensitive for significant neoplasms [colorectal cancer (CRC), advanced adenomatous polyps (AAP)], but faulted by non-specificity for human haemoglobin (Hb)...
  77. ncbi A sensitive guaiac faecal occult blood test is less useful than an immunochemical test for colorectal cancer screening in a Chinese population
    B C Y Wong
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Aliment Pharmacol Ther 18:941-6. 2003
    Colorectal cancer screening by guaiac faecal occult blood test has been shown to reduce the incidence and mortality of colorectal cancer in Western populations...
  78. pmc Costs and cost-effectiveness of full implementation of a biennial faecal occult blood test screening program for bowel cancer in Australia
    Michael P Pignone
    Lineberger Comprehensive Cancer Center, Cecil G Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, NC, USA
    Med J Aust 194:180-5. 2011
    ..To examine the costs and cost-effectiveness of full implementation of biennial bowel cancer screening for Australian residents aged 50-74 years...
  79. ncbi Immunochemical versus guaiac occult blood stool tests: results of a community-based screening program
    N Petrelli
    Department of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, New York 14263
    Surg Oncol 3:27-36. 1994
    This study was designed to investigate two guaiac-based and one immunochemical faecal occult blood test in a community screening program...
  80. ncbi High yield of colorectal neoplasia detected by colonoscopy following a positive faecal occult blood test in the NHS Bowel Cancer Screening Programme
    Thomas J W Lee
    Tees Bowel Cancer Screening Centre, University Hospital of North Tees, Stockton on Tees, UK
    J Med Screen 18:82-6. 2011
    The UK National Health Service Bowel Cancer Screening Programme (BCSP) is based on a strategy of biennial faecal occult blood (FOB) testing...
  81. ncbi Measuring the quality of colorectal cancer screening: the importance of follow-up
    David A Etzioni
    Department of General Surgery, David Geffen School of Medicine, UCLA, Los Angeles, California 90403, USA
    Dis Colon Rectum 49:1002-10. 2006
    ..This study examines patterns of colorectal cancer screening and follow-up within the nation's largest integrated health care system: the Veterans Health Administration...
  82. ncbi A combination of serum markers for the early detection of colorectal cancer
    Norbert Wild
    Department of New Technologies, Roche Diagnostics GmbH, Penzberg, Germany
    Clin Cancer Res 16:6111-21. 2010
    Fecal occult blood testing is recommended as first-line screening to detect colorectal cancer (CRC). We evaluated markers and marker combinations in serum as an alternative to improve the detection of CRC.
  83. ncbi Nonmedical costs of colorectal cancer screening with the fecal occult blood test and colonoscopy
    Steven J Heitman
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Clin Gastroenterol Hepatol 6:912-917.e1. 2008
    ..The nonmedical costs of colorectal cancer screening are unknown. However, they might influence screening uptake and impact the cost-effectiveness of colorectal cancer screening modalities...
  84. ncbi Effect of dietary restriction on participation in faecal occult blood test screening for colorectal cancer
    S R Cole
    Bowel Health Service, Repatriation General Hospital, Adelaide, SA
    Med J Aust 175:195-8. 2001
    OBJECTIVES: To determine if participation in colorectal cancer screening using faecal occult blood testing (FOBT) is affected by a restrictive diet and if it is associated with certain demographic variables...
  85. ncbi Meta-analysis of dietary restriction during fecal occult blood testing
    M Pignone
    Department of Medicine, University of North Carolina Chapel Hill School of Medicine, Chapel Hill, NC, USA
    Eff Clin Pract 4:150-6. 2001
    Dietary restriction is often recommended during fecal occult blood testing (FOBT) as a means of increasing test accuracy, but concern surrounds whether such restriction also reduces the chance that patients will complete the test.
  86. ncbi Hemoccult sensitivity estimate in a screening program for colorectal cancer in the Province of Florence
    G Castiglione
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Tumori 77:243-5. 1991
    ..Screening every year would achieve too limited an increase in sensitivity, compared to biennal screening, to be worth the difficulties of doubling organizational efforts and costs...
  87. ncbi Population screening for colorectal cancer: comparison between guaiac and immunological faecal occult blood tests
    M H Robinson
    Department of Surgery, University Hospital, Nottingham, UK
    Br J Surg 81:448-51. 1994
    There is concern about the low sensitivity of the guaiac-based Haemoccult test in mass population faecal occult blood (FOB) screening for the early detection of colorectal carcinoma...
  88. ncbi Fifteen years of bowel cancer screening policy in Australia: putting evidence into practice?
    Kathy L Flitcroft
    Sydney School of Public Health, University of Sydney, Sydney, NSW
    Med J Aust 193:37-42. 2010
    ....
  89. ncbi [National colorectal cancer screening program in the Republic of Croatia--experiences, outcomes and obstacles in the program implementation in the Medimurje County]
    Renata Kutnjak Kis
    Institute of Public Health of Medimurje County, Cakovec, Croatia
    Acta Med Croatica 64:363-74. 2010
    ..CRC mortality can be reduced by repeat screening by fecal occult blood testing (FOBT)...
  90. ncbi A randomized trial of direct mailing of fecal occult blood tests to increase colorectal cancer screening
    Timothy R Church
    Division of Environmental and Occupational Health, University of Minnesota, Minneapolis 55455, USA
    J Natl Cancer Inst 96:770-80. 2004
    Although colorectal cancer screening by using a fecal occult blood test (FOBT), flexible sigmoidoscopy, colonoscopy, or barium enema x-ray reduces the incidence of and death from colorectal cancer, the rate of colorectal cancer screening ..
  91. pmc A comparative case study of bowel cancer screening in the UK and Australia: evidence lost in translation?
    K L Flitcroft
    Health Policy, Screening and Test Evaluation Program, Sydney School of Public Health, Edward Ford Building, A27, University of Sydney, NSW 2006, Australia
    J Med Screen 18:193-203. 2011
    ....
  92. pmc Evaluation of a card collection-based faecal immunochemical test in screening for colorectal cancer using a two-tier reflex approach
    Callum G Fraser
    Scottish Bowel Screening Centre Laboratory, Kings Cross, Dundee DD3 8EA, UK
    Gut 56:1415-8. 2007
    The guaiac faecal occult blood test (gFOBT) has been proved as a screening investigation for colorectal cancer, but has disadvantages...
  93. ncbi Impact of a population-based colorectal cancer screening program on local health services demand in Italy: a 7-year survey in a northern province
    Fabrizio Parente
    Gastroenterology Unit, Alessandro Manzoni Hospital, Lecco, Italy
    Am J Gastroenterol 106:1986-93. 2011
    ..Health Service recommended a population-based colorectal cancer (CRC) screening program using biennial fecal occult blood testing (FOBT), followed by total colonoscopy in positive patients...
  94. pmc Option appraisal of population-based colorectal cancer screening programmes in England
    Paul Tappenden
    School of Health and Related Research, The University of Sheffield, Regent Court, 30 Regent Street, Sheffield S1 4DA, UK
    Gut 56:677-84. 2007
    To estimate the effectiveness, cost-effectiveness and resource impact of faecal occult blood testing (FOBT) and flexible sigmoidoscopy (FSIG) screening options for colorectal cancer to inform the Department of Health's policy on bowel ..
  95. pmc Protective effect of faecal occult blood test screening for colorectal cancer: worse prognosis for screening refusers
    Y Niv
    Department of Gastroenterology, Rabin Medical Center, Beilinson Campus, Tel Aviv University, Israel
    Gut 50:33-7. 2002
    Screening for colorectal cancer (CRC) by faecal occult blood testing (FOBT) decreases CRC mortality by 15-33%. Compliance remains an obstacle to maximising the benefit of FOBT screening...
  96. ncbi Occult and obscure gastrointestinal bleeding: causes and clinical management
    Don C Rockey
    University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 8887, USA
    Nat Rev Gastroenterol Hepatol 7:265-79. 2010
    ..Patients with occult gastrointestinal bleeding include those with fecal occult blood and iron-deficiency anemia (IDA)...
  97. ncbi Cancer screening before and after switching to a high-deductible health plan
    J Frank Wharam
    Department of Ambulatory Care and Prevention, Harvard Medical School, Harvard Pilgrim Health Care, and Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Ann Intern Med 148:647-55. 2008
    ..Health plans with high deductibles could lead patients to avoid preventive care, such as cancer screening...
  98. ncbi Utilization of lower gastrointestinal endoscopy and fecal occult blood test in 11 European countries: evidence from the Survey of Health, Aging and Retirement in Europe (SHARE)
    C Stock
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center DKFZ, Heidelberg, Germany
    Endoscopy 42:546-56. 2010
    Lower gastrointestinal endoscopy (sigmoidoscopy and colonoscopy) and the fecal occult blood test (FOBT) are thought to impact on colorectal cancer incidence and mortality...
  99. pmc Test, episode, and programme sensitivities of screening for colorectal cancer as a public health policy in Finland: experimental design
    Nea Malila
    Finnish Cancer Registry, Pieni Roobertinkatu 9, 00130 Helsinki, Finland
    BMJ 337:a2261. 2008
    To report the sensitivities of the faecal occult blood test, screening episode, and screening programme for colorectal cancer and the benefits of applying a randomised design at the implementation phase of a new public health policy.
  100. ncbi Colorectal cancer screening comparing no screening, immunochemical and guaiac fecal occult blood tests: a cost-effectiveness analysis
    Leo G M van Rossum
    Department of Epidemiology, Biostatistics and HTA, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Int J Cancer 128:1908-17. 2011
    ..trial to compare cost-effectiveness of screening with either one round of immunochemical fecal occult blood testing (I-FOBT; OC-Sensor®), one round of guaiac FOBT (G-FOBT; Hemoccult-II®) or no screening in Dutch aged ..
  101. ncbi Characteristics of colorectal cancer that produce positive immunochemical occult blood test results on stool obtained by digital rectal examination
    H Nakama
    Department of Public Health, Shinshu University School of Medicine, Matsumoto, Japan
    Can J Gastroenterol 15:227-30. 2001
    To clarify the clinicopathological features of colorectal cancer that show positive results on an immunochemical fecal occult blood test of stool obtained by digital rectal examination.

Research Grants67

  1. A MicroRNA Approach to Screen for Sporadic Colon Cancer Exfoliately in Human Stoo
    Farid E Ahmed; Fiscal Year: 2010
    ..The guaiac-based fecal occult blood test is the only screening test proved to be effective in reducing CRC mortality by three randomized clinical ..
  2. Interactive Multimedia Intervention to Improve Colonoscopy and Bowel Prep Adhere
    JOHN MATTHEW INADOMI; Fiscal Year: 2012
    ..Regardless of the primary strategy (fecal occult blood testing, sigmoidoscopy, colonoscopy, fecal DNA, computed tomographic colonography [virtual colonoscopy]) ..
  3. Development of a Urine Test for the Early Detection of Colon Cancer
    Wei Song; Fiscal Year: 2012
    ..Current available noninvasive CRC screening tests include the fecal occult blood test (FOBT), fecal immunochemical test (FIT), the stool DNA test (PreGenPlus, Exact Sciences, Maynard, MA), ..
  4. Who benefits from Colorectal Cancer Screening? A subgroup Analysis of the Minnes
    Aasma Shaukat; Fiscal Year: 2013
    1. To determine the effect of fecal occult blood testing (FOBT) screening on colorectal cancer mortality, non- colorectal cancer mortality and all-cause mortality in the Minnesota Colon Cancer Control Study, (MCCCS) updated to 2006 2...
  5. Improving Gastrointestinal Disease Outcomes in Vulnerable Populations
    JOHN MATTHEW INADOMI; Fiscal Year: 2012
    ..at average risk for development of polyps in which subjects receive counseling about screening using fecal occult blood testing or colonoscopy or their choice of either test...
  6. Barriers to CRC in patients with mental illness.
    Arpita Aggarwal; Fiscal Year: 2010
    ..Health Administration data suggests that patients with mental illnesses have lower rates of annual fecal occult blood testing compared to an age and sex matched cohort of patients without mental illnesses...
  7. Nanocytological Fecal Assessment to Personalize Colonoscopic Surveillance
    Hemant K Roy; Fiscal Year: 2013
    ..Fecal tests represent an attractive potential adjunct although the typical tests (occult blood, DNA, methylation) have a poor (~10-40%) sensitivity for advanced adenomas, the target of CRC prevention ..
  8. PRE-VIEW An Interactive Video Doctor to Encourage Cancer Screening
    JUDITH MARY EILEEN WALSH; Fiscal Year: 2013
    ..of screening for breast cancer with mammography;cervical cancer with Pap tests;or colorectal cancer with fecal occult blood tests, fecal immunochemical tests, sigmoidoscopy or colonoscopy when indicated and to engage in shared decision-..
  9. CT Colonoscopy Screening for CRC:Comparative Effectiveness vs Traditional Models
    G Scott Gazelle; Fiscal Year: 2010
    ..Randomized trials of colorectal cancer screening with a fecal occult blood test (FOBT) show a 20% reduction in cancer incidence and a 15% to 33% reduction in cancer mortality...
  10. THE FLU-FOBT PROGRAM: TRANSLATION OF AN EVIDENCE-BASED COLORECTAL CANCER SCREENI
    Michael B Potter; Fiscal Year: 2010
    ..In these settings the primary CRCS option for average risk patients is annual home fecal occult blood testing (FOBT), a test that has been shown in several studies to reduce colorectal cancer mortality...
  11. Systems of Support (SOS) to Increase Colon Cancer Screening and Follow-up
    BEVERLY BETH GREEN; Fiscal Year: 2013
    ..due for screening (n=4675) were randomized to (1) Usual Care, (2) Automated care (automated mailings and fecal occult blood tests), (3) automated plus assisted care from medical assistants (phone reminders and sending orders to ..
  12. Preclinical assay development of a novel Colon Cancer Marker (CCSA-4)
    JACK CLEMENS; Fiscal Year: 2007
    ..Several methods are available for detection of colon cancer, including fecal occult blood testing, flexible sigmoidoscopy, double contrast barium enema and colonoscopy...
  13. DEterminants of Timely Evaluation Colonoscopy for crc+ screening Tests
    Melissa R Partin; Fiscal Year: 2013
    Item 6 Project Summary/Abstract a) Project Background/Rationale. Fecal Occult Blood Testing (FOBT), the primary screening mode employed by the Veterans Health Administration (VA), can be a highly efficacious colorectal cancer screening ..
  14. Maximizing yield of the fecal immunochemical test for colorectal cancer screening
    ELIZABETH GRACE LILES; Fiscal Year: 2013
    ..Screening for CRC reduces CRC mortality, yet rates of screening in the United States remain low. Fecal occult blood testing (FOBT) is the only CRC screening method with an established positive balance of benefit and risk, is ..
  15. Tailored Touchscreen Colorectal Cancer Prevention in American Indian Communities
    K Allen Greiner; Fiscal Year: 2013
    ..screen administered assessment and, depending on stated preference, be offered either an immunochemical fecal occult blood test (iFOBT-InSure TM) or colonoscopy...
  16. Tailored Interactive Multimedia to Reduce Colorectal CA Screening Disparities
    ANTHONY FRANCIS JERANT; Fiscal Year: 2013
    ..Screening methods targeted will be fecal occult blood testing, flexible sigmoidoscopy, and colonoscopy...
  17. Quantifying Risk to Target Screening Colonoscopy
    Thomas Imperiale; Fiscal Year: 2009
    ..known as "advanced neoplasia") could allow use of different screening tests (CY, sigmoidoscopy, fecal occult blood) to be tailored to risk...
  18. An Interactive Preventive Health Record to Increase Colorectal Cancer Screening
    Resa M Jones; Fiscal Year: 2013
    ..CRCS) recommendations and interventions to increase adherence can be less than optimally effective (fecal occult blood test kit mailings) or expensive (patient navigators)...
  19. PROSPECTIVE COMPARISON OF COLONIC IMAGING TEST
    Don Rockey; Fiscal Year: 2001
    ..by patients and to determine which is the most cost-effective approach for evaluation of patients with fecal occult blood, the major indication for colonic imaging...
  20. Increasing Colon Cancer Screening in Primary Care
    Ronald Myers; Fiscal Year: 2004
    ABSTRACT=The American Cancer Society recommends that men and women 50 or more years of age have a annual fecal occult blood test (FOBT) and a flexible sigmoidoscopy (FS) examination every five years to screen for colorectal cancer (CRC)...
  21. Role of Physicians and Their Groups in Cancer Screening
    George Wright; Fiscal Year: 2005
    ..the year 2002 will be analyzed to calculate rates for five screening tests (mammography, sigmoidoscopy, fecal occult blood, PAP smears, and PSA tests)...
  22. Colorectoral cancer screening decisions in primary care
    James Dolan; Fiscal Year: 2006
    ..Current screening guidelines for average risk patients endorse 5 options: annual fecal occult blood tests, flexible sigmoidoscopy every 5 years, combined annual fecal occult blood tests and flexible ..
  23. Adherence and the Economics of Colon Cancer Screening
    John Inadomi; Fiscal Year: 2009
    ..Strategies to be evaluated include fecal occult blood testing (FOBT), flexible sigmoidoscopy (FS), colonoscopy, and virtual colonoscopy (VC, when approved for CRC ..
  24. Tailored Touchscreen Colorectal Cancer Prevention in Urban Core Clinics
    K Allen Greiner; Fiscal Year: 2010
    ..screen administered assessment and, depending on stated preference, be offered either an immunochemical fecal occult blood test (iFOBT-lnSure"), colonoscopy, or sigmoidoscopy...
  25. ENHANCING DIAGNOSTIC EVALUATION IN COLORECTAL CANCER
    Ronald Myers; Fiscal Year: 1999
    DESCRIPTION: Complete diagnostic evaluation (CDE) for persons with positive results on fecal occult blood testing (FOBT plus) is a key component of colorectal cancer screening...
  26. ADDING NEW FECAL OCCULT BLOOD TESTS TO SIGMOIDOSCOPY
    Theodore Levin; Fiscal Year: 2000
    ..Colorectal cancer (CRC) screening reduces mortality, but it remains unclear whether the combination of a fecal occult blood test (FOBT) and sigmoidoscopy offers any advantage over either method used alone...
  27. CONTROL OF LARGE BOWEL CANCER FOLLOWING POLYPECTOMY
    Sidney Winawer; Fiscal Year: 1991
    ..randomization; continuation of follow-up of currently enrolled patients with an annual questionnaire and fecal occult blood test, and at 6 years with a complete colonoscopy and double contrast barium enema; and implementation of a ..
  28. Predictors of Cancer Screening in Diverse Practices
    Richard Zimmerman; Fiscal Year: 2005
    ..6 percent reported fecal occult blood screening (FOBT) within the last year and 33...
  29. A Test of Iron Malabsorption in Patients with IDA
    Morteza Janghorbani; Fiscal Year: 2005
    ..Despite thorough GI tract evaluation, a significant number of patients are found to be negative for fecal occult blood (FOB) and >30% do not have lesions consistent with chronic blood loss, suggesting that iron (Fe) ..
  30. HEALTHTOUCH--COMPUTER-ASSISTED CANCER PREVENTION
    W MC CARTER; Fiscal Year: 1992
    ..activities, including mammogram, BSE, physician breast examination, pap smears, flexible sigmoidoscopy, fecal occult blood tests, digital rectal exams, and oral examinations...
  31. Colorectal Cancer Screening in Chinese Americans
    Shin Ping Tu; Fiscal Year: 2004
    ..The overall goal of this research is to increase the uptake of fecal occult blood testing (FOBT) by Chinese Americans...
  32. RANDOMIZED TRIAL TO EVALUATE SCREENING FOR COLON CANCER
    Timothy Church; Fiscal Year: 1999
    ..Control Study (CCCS), a randomized controlled trial, is designed to evaluate the effectiveness of a fecal occult blood test (Hemoccult) in reducing mortality from colorectal cancer...
  33. A New Marker for Colon Cancer Screening
    Robert Kinders; Fiscal Year: 2001
    ..In a head-to-head comparison with two different fecal occult blood tests (FOBT), the prototype sandwich assay has demonstrated superior clinical diagnostic performance to both...
  34. High Sensitivity Molecular Test for Colorectal Cancer
    Mark Lim; Fiscal Year: 2005
    ..During Phase II, an optimized non-invasive assay system will be evaluated for CRC population screening. ..
  35. Molecular Biomarkers/Non-invasive Diagnosis Of Colon CA
    SMITI GUPTA; Fiscal Year: 2002
    ..Present screening methods include fecal occult blood testing (FOBT) and endoscopy, which can detect some early colon cancers and large polyps...
  36. COMMUNITY TRIAL TO INCREASE CANCER SCREENING ADHERENCE
    Sarah Fox; Fiscal Year: 2002
    ..Task Force for women over age 50, include mammography, clinical breast examination (CBE), Pap smear, and fecal occult blood test (FOBT). In spite of widespread endorsement, many women do not systematically receive these tests...
  37. CASE-CONTROL EVALUATIONS OF COLORECTAL CANCER SCREENING
    Joe Selby; Fiscal Year: 1990
    ..to evaluate the efficacy of three screening tests - digital rectal examination, sigmoidoscopy, and fecal occult blood testing - in reducing mortality from colorectal cancer...
  38. Increasing Screening Colonoscopy Among Minority Women
    Moshe Shike; Fiscal Year: 2004
    ..S. with an estimated incidence of 148,000 cases and 56,000 deaths in 2002. CRC screening (CRCS) by fecal occult blood testing has been shown to reduce mortality...
  39. INCREASING SCREENING ADHERENCE THROUGH A PHYSICIAN TRIAL
    Sarah Fox; Fiscal Year: 2003
    ..Task Force for women over age 50, include mammography, clinical breast exam (CBE), pap smear, and fecal occult blood test (FOBT)...
  40. IMPROVING COLORECTAL CANCER SCREENING RATES
    Patricia Ganz; Fiscal Year: 2001
    ..The goal for the intervention program will be to increase colorectal cancer screening rates with fecal occult blood testing (FOBT) and flexible sigmoidoscopy in men and women age greater than or equal to 50 years who are ..
  41. A Novel-Invasive CRC Test Based on Mass Spec of In Vitro Expressed Proteins
    James Han; Fiscal Year: 2006
    ..For the purpose of assay validation and eventual FDA approval, AmberGen will work closely with Quest Diagnostics, Inc., which operates the largest network of in vitro diagnostic testing facilities in the U.S. [unreadable] [unreadable]..
  42. IMPROVING COLORECTAL CANCER SCREENING BY OB/GYNS
    David Weinberg; Fiscal Year: 2002
    DESCRIPTION: (Applicant's Description) Appropriate colorectal cancer (CRC) screening using fecal occult blood testing (FOBT) can substantially reduce CRC mortality...
  43. DETECTION OF EARLY COLON CANCER
    Sidney Winawer; Fiscal Year: 1980
    ..Improved survival may be possible by screening asymptomatic patients at risk with currently available fecal occult blood tests coupled with available sensitive radiologic and endoscopic diagnostic techniques...
  44. CANCER PREVENTION IN PRIMARY CARE--PATIENT ACTIVATION
    Russell Harris; Fiscal Year: 1999
    ..multiple cancer risk behaviors mammography and clinical breast exam; PAP testing; sigmoidoscopy and fecal occult blood testing; and smoking)...
  45. Intervention for Colorectal Cancer
    Charles Bennett; Fiscal Year: 2003
    ..aims are to: 1) assess patient and physician factors that affect the use of colorectal screening with fecal occult blood testing (FOBT) and flexible sigmoidoscopy in the primary care setting, and 2) develop and evaluate the ..
  46. EVALUATION OF EFFICACY OF FECAL OCCULT BLOOD TEST
    DeAnn Lazovich; Fiscal Year: 1993
    Although widely used as a screening test for the early detection of colorectal cancer, the efficacy of fecal occult blood testing (FOBT), to prevent death from colorectal cancer is unknown...
  47. Development of a Cancer Specific PCNA Tumor Marker Immu*
    Cha Mei Tang; Fiscal Year: 2004
    ..S. alone. Currently some 50 million Pap smears, 30 million mammograms, 30 million PSA tests, 20 million occult blood tests, and 2.5 million biopsies are performed annually for these purposes.
  48. CULTURAL METHODS--DECREASE CANCER FATALISM AMONG BLACKS
    Barbara Powe; Fiscal Year: 1999
    ..to reduce cancer fatalism, increase knowledge of colorectal cancer, and increase participation in fecal occult blood testing among rural African American elders...
  49. Colorectal Cancer Screening Preferences in Primary Care
    Sarah Hawley; Fiscal Year: 2005
    ..as trading test accuracy for invasiveness; 2) potential "what if' situations, such as a more accurate fecal occult blood test or virtual colonoscopy, can be easily evaluated using CA; and 3) the approach identifies characteristics ..
  50. Colorectal Screening in Vietnamese : A Controlled Trial
    Bang Nguyen; Fiscal Year: 2006
    ..of colorectal screening is low among Vietnamese Americans; only 35 percent of Vietnamese have ever had a fecal occult blood test...
  51. SIMPLE LAB TEST FOR LOCALIZING GI BLEEDING SITE
    BRIAN CRAINE; Fiscal Year: 1999
    ..The largest market for this test will be in the evaluation of patients with occult blood in their stool...
  52. CORI: Consortium Expansion and Database Enhancement
    David Lieberman; Fiscal Year: 2004
    ....
  53. Screening for colortectal cancer in an Asian Community Center
    David Lieberman; Fiscal Year: 2008
    ..This is a new paradigm for screening, which takes advantage of the trust and cultural awareness that exists at the community center and does not rely on the primary care provider. [unreadable] [unreadable] [unreadable] [unreadable]..
  54. The effect of physical activity on metabolic syndrome in pregnancy and fetal outc
    Cynthia Ko; Fiscal Year: 2008
    ..It may offer a safe and readily available method to control weight and improve infant health during and after pregnancy. [unreadable] [unreadable] [unreadable]..
  55. Epidemiology of hepatocellular carcinoma
    Cynthia Ko; Fiscal Year: 2006
    ....
  56. A Primary-Care Based Colorectal Cancer Screening Program
    Cynthia Ko; Fiscal Year: 2006
    ..shown that only a minority of people over the age of 50 is screened for colorectal cancer with either focal occult blood testing or flexible sigmoidoscopy. Barriers to screening include patient and provider-related factors...
  57. Colonoscopy quality and outcomes in clinical practice
    Cynthia W Ko; Fiscal Year: 2010
    ..The various algorithms we develop will be tested in a second, validation subset of our database to find the algorithm with optimal performance characteristics. ..
  58. INCREASING ACCESS TO CLINICAL AND EDUCATIONAL STUDIES
    Ronald Myers; Fiscal Year: 2004
    ..In Phase 3, we will prepare and submit new research grant applications based on results from the pilot studies. ..
  59. Insulin Resistance and Adenomas of the Colorectum
    Theodore Levin; Fiscal Year: 2003
    ..abstract_text> ..
  60. Evaluation of Enteral Stent Placement Using Claims Data
    Sujha Subramanian; Fiscal Year: 2004
    ..abstract_text> ..
  61. Promoting Colon Cancer Screening Among African Amercians
    Susan M Rawl; Fiscal Year: 2010
    ..to promote CRC screening among African Americans resulted in increased CRC knowledge and higher rates of fecal occult blood testing...
  62. Tailored Messaging in Colorectal Cancer Screening
    Ronald Myers; Fiscal Year: 2005
    ..Determine intervention impact on CRC screening utilization, 2. Determine intervention impact on screening decision stage, and 3. Determine intervention impact on patient perceptions about screening. ..
  63. Increasing screening in families with colorectal cancer
    Susan Rawl; Fiscal Year: 2003
    ..Transition probabilities for stage of change will be calculated separately for the intervention groups for each screening test. ..
  64. Primary Care Colorectal Ca Screening Surveillance System
    Richard Hoffman; Fiscal Year: 2005
    ..type, screening programs) characteristics; delivery of colorectal cancer screening tests, including fecal occult blood testing, endoscopic procedures, and radiolologic procedures; patient utilization of these screening services; ..