erythrocyte count

Summary

Summary: The number of RED BLOOD CELLS per unit volume in a sample of venous BLOOD.

Top Publications

  1. ncbi Screening toxicity study in young carp (Cyprinus carpio L.) on feed amended with fumonisin B1
    Stjepan Pepeljnjak
    Department of Microbiology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovacica 1, 10000 Zagreb, Croatia
    Mycopathologia 156:139-45. 2003
  2. ncbi [Simple hematological blood tests and urine and stool tests for diagnosis of rheumatoid arthritis]
    Masahiro Yamamura
    Department of Medicine and Clinical Science, Graduate School of Medicine and Dentistry, Okayama University
    Nihon Rinsho 63:297-300. 2005
  3. ncbi Lead decreases parasitemia and enhances survival of Plasmodium berghei-infected mice
    Saisudha Koka
    Department of Physiology, University of Tubingen, Gmelinstr 5, D 72076 Tubingen, Germany
    Biochem Biophys Res Commun 363:484-9. 2007
  4. pmc Subclinical lung disease, macrocytosis, and premature graying in kindreds with telomerase (TERT) mutations
    Alberto Diaz de Leon
    McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX, 75390 8591, USA
    Chest 140:753-63. 2011
  5. ncbi Human red blood cell aging: correlative changes in surface charge and cell properties
    Yao Xiong Huang
    Institute of Biomedical Engineering, Ji Nan University, Guang Zhou, China
    J Cell Mol Med 15:2634-42. 2011
  6. ncbi A retrospective examination of anemia during infection of humans with Plasmodium vivax
    William E Collins
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Am J Trop Med Hyg 68:410-2. 2003
  7. ncbi Red cell distribution width in heart failure: prediction of clinical events and relationship with markers of ineffective erythropoiesis, inflammation, renal function, and nutritional state
    Zsolt Förhécz
    3rd Department of Internal Medicine, and Szentágothai Knowledge Center, Semmelweis University, Budapest, Hungary
    Am Heart J 158:659-66. 2009
  8. ncbi A role of phosphatidylserine externalization in clearance of erythrocytes exposed to stress but not in eliminating aging populations of erythrocyte in mice
    Sanjay Khandelwal
    School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India
    Exp Gerontol 43:764-70. 2008
  9. ncbi Hematological and serum biochemical indices in healthy bonnet macaques (Macaca radiata)
    Peter J Pierre
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, NC, USA
    J Med Primatol 40:287-93. 2011
  10. pmc Competition for red blood cells can enhance Plasmodium vivax parasitemia in mixed-species malaria infections
    Philip G McQueen
    Center for Information Technology and Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892 5620, USA
    Am J Trop Med Hyg 75:112-25. 2006

Research Grants

Detail Information

Publications243 found, 100 shown here

  1. ncbi Screening toxicity study in young carp (Cyprinus carpio L.) on feed amended with fumonisin B1
    Stjepan Pepeljnjak
    Department of Microbiology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovacica 1, 10000 Zagreb, Croatia
    Mycopathologia 156:139-45. 2003
    ..nova) in the group treated with the higher FB1 dose. Several hematological parameters (erythrocyte count, platelet count) and serum chemical concentrations (creatinin, total bilirubin) and activities (aspartate ..
  2. ncbi [Simple hematological blood tests and urine and stool tests for diagnosis of rheumatoid arthritis]
    Masahiro Yamamura
    Department of Medicine and Clinical Science, Graduate School of Medicine and Dentistry, Okayama University
    Nihon Rinsho 63:297-300. 2005
  3. ncbi Lead decreases parasitemia and enhances survival of Plasmodium berghei-infected mice
    Saisudha Koka
    Department of Physiology, University of Tubingen, Gmelinstr 5, D 72076 Tubingen, Germany
    Biochem Biophys Res Commun 363:484-9. 2007
    ..berghei harbouring erythrocytes. In conclusion, Pb(NO3)2 accelerates eryptosis and subsequent clearance of infected erythrocytes and thus favourably influences the course of malaria...
  4. pmc Subclinical lung disease, macrocytosis, and premature graying in kindreds with telomerase (TERT) mutations
    Alberto Diaz de Leon
    McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX, 75390 8591, USA
    Chest 140:753-63. 2011
    ..The subclinical phenotypes of asymptomatic members of these families have not been evaluated with respect to TERT mutation status or telomere length...
  5. ncbi Human red blood cell aging: correlative changes in surface charge and cell properties
    Yao Xiong Huang
    Institute of Biomedical Engineering, Ji Nan University, Guang Zhou, China
    J Cell Mol Med 15:2634-42. 2011
    ..This quantitative approach not only clarifies the picture but also has implications in biology and medicine...
  6. ncbi A retrospective examination of anemia during infection of humans with Plasmodium vivax
    William E Collins
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Am J Trop Med Hyg 68:410-2. 2003
    ..An equilibrium appeared to be established between weeks 4 and 6. Decreases in Hb concentrations were greatest following the first week of parasitemia. Total restoration to preinfection levels did not occur during persistent parasitemia...
  7. ncbi Red cell distribution width in heart failure: prediction of clinical events and relationship with markers of ineffective erythropoiesis, inflammation, renal function, and nutritional state
    Zsolt Förhécz
    3rd Department of Internal Medicine, and Szentágothai Knowledge Center, Semmelweis University, Budapest, Hungary
    Am Heart J 158:659-66. 2009
    ..Understanding the mechanism underlying this observation is unclear, largely hampered by the lack of epidemiologic studies demonstrating factors that are associated with anisocytosis in cardiovascular diseases...
  8. ncbi A role of phosphatidylserine externalization in clearance of erythrocytes exposed to stress but not in eliminating aging populations of erythrocyte in mice
    Sanjay Khandelwal
    School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India
    Exp Gerontol 43:764-70. 2008
    ....
  9. ncbi Hematological and serum biochemical indices in healthy bonnet macaques (Macaca radiata)
    Peter J Pierre
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, NC, USA
    J Med Primatol 40:287-93. 2011
    ..The goal of this study was to determine reference ranges for hematological and serum biochemical indices in healthy, socially housed bonnet macaques for males and females over a range of ages...
  10. pmc Competition for red blood cells can enhance Plasmodium vivax parasitemia in mixed-species malaria infections
    Philip G McQueen
    Center for Information Technology and Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892 5620, USA
    Am J Trop Med Hyg 75:112-25. 2006
    ..Furthermore, transients in RBC production can induce coupled oscillations in the parasitemia of both species. These results are remarkably robust to changes in model parameters...
  11. ncbi Hematologic and serum biochemical values in aged female bonnet macaques (Macaca radiata) anesthetized with ketamine hydrochloride
    Ramasamy Venkatesan
    Primate Research Center, National Institute of Immunology, New Delhi, India
    J Am Assoc Lab Anim Sci 45:45-8. 2006
    ..These findings will be useful in designing experiments assessing pathologic and toxicologic changes in blood and serum parameters and interpreting data obtained from aged bonnet monkeys...
  12. ncbi Effects of fasting on hematologic and clinical chemical values in cynomolgus monkeys (Macaca fascicularis)
    X C Zeng
    National Shanghai Center for Drug Safety Evaluation and Research, Shanghai Institute of Pharmaceutical Industry, Shanghai, China
    J Med Primatol 40:21-6. 2011
    ..The aim of this study was to evaluate the influence of fasting on clinical pathology parameters in healthy adult cynomolgus monkeys...
  13. ncbi Aging of red blood cells and impaired erythropoiesis following prolonged administration of dichloromethylene diphosphonate containing liposomes in rats
    Anna Lisa Giuliani
    Department of Experimental and Diagnostic Medicine, Section of General Pathology, University of Ferrara, Ferrara, Italy
    Eur J Haematol 75:406-16. 2005
    ..To investigate whether macrophage-depleted rats may serve as a model for studying red blood cell (RBC) aging...
  14. ncbi Lower red blood cell counts in middle-aged subjects with shorter peripheral blood leukocyte telomere length
    Tim De Meyer
    Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, Ghent, Belgium
    Aging Cell 7:700-5. 2008
    ..While negligible in a middle-aged population, the clinical consequences might be important in the elderly (e.g. in anemia of chronic disease). Further studies are required to confirm the impact of our results...
  15. pmc Erythrocytes and the regulation of human skeletal muscle blood flow and oxygen delivery: role of erythrocyte count and oxygenation state of haemoglobin
    Jose Gonzalez-Alonso
    Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, Middlesex UB8 3PH, UK
    J Physiol 572:295-305. 2006
    ....
  16. ncbi Comparative study of circadian variation in numbers of peripheral blood cells among mouse strains: unique feature of C3H/HeN mice
    Naoki Ohkura
    Clinical Molecular Biology, Faculty of Pharmaceutical Sciences, Teikyo University, Tsukui, Kanagawa, Japan
    Biol Pharm Bull 30:1177-80. 2007
    ..The present observations provide basic information about the numbers of peripheral blood cells and their circadian rhythm in mouse models and also demonstrate a unique feature of C3H/HeN mice...
  17. pmc Modeling time variant distributions of cellular lifespans: increases in circulating reticulocyte lifespans following double phlebotomies in sheep
    Kevin J Freise
    College of Pharmacy, The University of Iowa, Iowa City, IA 52242, USA
    J Pharmacokinet Pharmacodyn 35:285-323. 2008
    ....
  18. ncbi Howell-Jolly body counting as a measure of splenic function. A reassessment
    G R Corazza
    Department of Internal Medicine, University of L Aquila, Italy
    Clin Lab Haematol 12:269-75. 1990
    ....
  19. ncbi Pharmacokinetics and pharmacodynamics of epoetin alfa once weekly and three times weekly
    W Cheung
    The R W Johnson Pharmaceutical Research Institute, Raritan, NJ 08869, USA
    Eur J Clin Pharmacol 57:411-8. 2001
    ..These results indicate that the epoetin alfa 150 IU/kg t.i.w. and 40,000 IU q.w. regimens can be considered clinically equivalent...
  20. ncbi Quantitative trait loci for baseline erythroid traits
    Luanne L Peters
    The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, USA
    Mamm Genome 17:298-309. 2006
    ..These analyses emphasize the genetic complexity underlying the regulation of erythroid peripheral blood traits in normal populations and suggest that genes not previously recognized as significantly impacting normal erythropoiesis exist...
  21. ncbi Possible mechanism for the anemia induced by candesartan cilexetil (TCV-116), an angiotensin II receptor antagonist, in rats
    I Naeshiro
    Drug Safety Research Laboratories, Takeda Chemical Industries, Osaka, Japan
    Eur J Pharmacol 354:179-87. 1998
    ..In the TCV-116 group, the erythrocyte count, hematocrit value and hemoglobin concentration were decreased by 7-8% as compared with the values in the ..
  22. pmc Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans
    Ken Sin Lo
    Montreal Heart Institute, 5000 Belanger Street, Montreal, QC, H1T 1C8, Canada
    Hum Genet 129:307-17. 2011
    ..Our results show similarities but also differences in the genetic regulation of hematological traits in European- and African-derived populations, and highlight the role of natural selection in shaping these differences...
  23. ncbi Anemia due to losartan in hypertensive renal transplant recipients without posttransplant erythrocytosis
    A Ersoy
    Department of Nephrology, Uludag University Medical School, 16059 Gorukle Bursa, Turkey
    Transplant Proc 37:2148-50. 2005
    ..Based on the capacity of losartan to decrease Hb and Hct, this drug should be carefully used in patients with preexistent anemia or low Hb levels...
  24. ncbi Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after intravenous and subcutaneous administration in rats
    Sukyung Woo
    Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, 565 Hochstetter Hall, State University of New York at Buffalo, Buffalo, NY 14260, USA
    J Pharmacol Exp Ther 319:1297-306. 2006
    ..87 and SC(50) = 65.37 mIU/ml) and mean lifespans of major erythropoietic cell populations in rats...
  25. ncbi Arterial blood pressure. Correlation with erythrocyte count, hematocrit, and hemoglobin concentration
    B O Göbel
    Medizinische Universitäts Poliklinik Bonn, West Germany
    Am J Hypertens 4:14-9. 1991
    ..0001) and this was associated with higher values for erythrocyte count, hemoglobin concentration, and hematocrit in men as compared to women...
  26. ncbi Evidence for linkage of red blood cell size and count: genome-wide scans in the Framingham Heart Study
    Jing Ping Lin
    Office of Biostatistics Research NHLBI NIH, Bethesda, MD 20892 7938, USA
    Am J Hematol 82:605-10. 2007
    ..9. These findings suggest that further studies are warranted to identify potential causal genetic variants for RBC size and count and related erythrocyte indices...
  27. ncbi Menstruation does not cause anemia: endometrial thickness correlates positively with erythrocyte count and hemoglobin concentration in premenopausal women
    Kathryn B H Clancy
    Reproductive Ecology Laboratory, Department of Anthropology, Yale University, New Haven, Connecticut 06520 8277, USA
    Am J Hum Biol 18:710-3. 2006
    ..24, P = 0.05; r(2) = 0.25, P = 0.04, respectively). We propose that, contrary to popular understanding, a thicker endometrium suggests greater iron reserves, rather than greater risk for anemia, in healthy women...
  28. ncbi Haematological values in pregnant women in Port Harcourt, Nigeria
    D V B Dapper
    Department of Human Physiology, College of Health Sciences, University of Port Harcourt, Port Harcourt, Nigeria
    Niger J Med 15:237-40. 2006
    ....
  29. ncbi Blood lactoferrin release induced by running exercise in normal volunteers: antibacterial activity
    Hiroyoshi Inoue
    Radioisotopes Institute for Basic and Clinical Medicine, Kurume University School of Medicine, 67 Asahi Machi, Kurume 830 0011, Japan
    Clin Chim Acta 341:165-72. 2004
    ..The aim of this study was to determine serum lactoferrin concentrations and serum antibacterial activity before and after running exercise...
  30. ncbi Comparative studies on the infectivity of Theileria parva in ticks fed in vitro and those fed on cattle
    Joseph M Musyoki
    Kenyatta University, Nairobi, Kenya
    Exp Appl Acarol 32:51-67. 2004
    ..When the immunised cattle were challenged with a lethal homologous dose of T. parva (Marikebuni), they were found to be immune...
  31. ncbi Influence of dexamethasone on some cellular aspects of the immune system in cats
    M Hoffmann-Jagielska
    Department of Clinical Science, Faculty of Veterinary Medicine, Agricultural University of Warsaw, Nowoursynowska 159C, 02 786 Warsaw, Poland
    Vet Res Commun 27:643-52. 2003
    ..Dexamethasone also caused an increase in the number of B lymphocytes...
  32. ncbi Non-specific immunity-enhancing effects of tryptic casein hydrolysate versus Fermosorb for treatment/prophylaxis of newborn calf colibacillosis
    Gediminas A Biziulevicius
    Immunomodulators Research Sector, Institute of Immunology, Vilnius University, 29 Moletu plentas, LT 2021, Vilnius, Lithuania
    FEMS Immunol Med Microbiol 39:155-61. 2003
    ..The immunostimulatory activity of TCH most probably derives from a synergistic action of bioactive peptides encrypted in the preparation itself and the cell wall fragments resulting from microbial autolysis induction...
  33. ncbi Immune response of mice infested by Hyalomma dromedarii ticks infected with entomopathogenic nematodes
    Abdel Hakim Saad
    Department of Zoology, Faculty of Science, Cairo University, Egypt
    J Egypt Soc Parasitol 36:867-87. 2006
    ..Proinflammatory Thl T lymphocyte cytokines were suppressed and Th2 cytokines were enhanced for infestation with H. dromedarii. The data indicated a polarization of immune response towards Th2 lymphocytes...
  34. ncbi Clinico-haematological and mineral studies on experimental maduramicin toxicity in chickens
    Tersem Singh
    Department of Veterinary Pathology, CCS Haryana Agricultural University, 125 004, Hisar, India
    Vet Parasitol 116:345-53. 2003
    ..medication caused significant reduction in haemoglobin in both the medicated group from day 14 and total erythrocyte count and packed cell volume in 10 ppm group on day 21...
  35. ncbi Platelet count is independently associated with insulin resistance in non-obese Japanese type 2 diabetic patients
    Ataru Taniguchi
    Division of Diabetes, Kansai Denryoku Hospital, Osaka, Japan
    Metabolism 52:1246-9. 2003
    ..These results indicate that not only BMI, HbA(1c), and triglycerides levels but also platelet counts are independent predictor of insulin resistance in non-obese Japanese type 2 diabetic patients...
  36. ncbi [Establishing the reference range of venous blood measured by automated haematology analyzer in Chinese adults]
    Yu Long Cong
    Department of Clinical Laboratory, Chinese PLA General Hospital, Beijing 100853, China
    Zhonghua Yi Xue Za Zhi 83:1201-5. 2003
    ..To establish the reference range of venous blood measured by automated hematology analyzer in China...
  37. pmc Are published standards for haematological indices in pregnancy applicable across populations: an evaluation in healthy pregnant Jamaican women
    Tameika R James
    Department of Basic Medical Sciences, Physiology Section, Faculty of Medical Sciences, UWI, Mona Campus, Kingston 7, Jamaica, West Indies
    BMC Pregnancy Childbirth 8:8. 2008
    ....
  38. ncbi Bioaccumulation and damaging action of polymetal industrial dust on laboratory mice Mus musculus alba .II. Genetic, cell, and metabolic disturbances
    M Topashka-Ancheva
    Institute of Zoology, Bulgarian Academy of Sciences, Bd Tzar Osvoboditel 1, Sofia 1000, Bulgaria
    Environ Res 92:152-60. 2003
    ..An increase in hematocrit, accompanied by a loss of body weight after day 60, suggests dehydration resulting from lead and cadmium poisoning...
  39. ncbi Clinical and hematological effects of serial phlebotomy performed on laboratory beagles
    Tara G Ooms
    University of Illinois Chicago, Biologic Resources Laboratory, 1840 W Taylor Street, Chicago, Illinois 60612, USA
    Contemp Top Lab Anim Sci 43:38-42. 2004
    ..We conclude that removing 15% blood volume in laboratory beagles is compatible with maintaining the health and well-being of the dog and can be acceptable in laboratory situations when it is scientifically justified...
  40. ncbi Effects of feeding calves genetically modified corn bt11: a clinico-biochemical study
    Nobuaki Shimada
    Safety Research Team, National Institute of Animal Health, Ibaraki, Japan
    J Vet Med Sci 68:1113-5. 2006
    ..The results suggest that the transgenic Bt11 has no negative clinico-biochemical effects on calves...
  41. ncbi Effects of prolonged oral administration of aflatoxin B1 and fumonisin B1 in broiler chickens
    M Del Bianchi
    Departamento de Microbiologia, Instituto de Ciencias Biomedicas, Universidade de Sao Paulo, Sao Paulo, SP 05508 900, Brazil
    Poult Sci 84:1835-40. 2005
    ..Results indicated that FB1 and AFB1, singly or in combination at the levels evaluated, do not change markedly the hematological and serological parameters of broiler chickens, but may cause relevant lesions in liver and in kidneys...
  42. ncbi Hematological and biochemical changes in water buffalo calves (Bubalus bubalis) infected with Trypanosoma evansi
    M Hilali
    Parasitology Department, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt
    Vet Parasitol 139:237-43. 2006
    ..Kidney function tests revealed significant decrease of both creatinine and urea...
  43. ncbi [Effects of 1800 MHz GSM-like exposure on the gonadal function and hematological parameters of male mice]
    Zsolt Forgacs
    Országos Kémiai Biztonsági Intézet, Fodor József Országos Közegészségügyi Központ, Budapest 1450, Hungary
    Magy Onkol 49:149-51. 2005
    ..Further investigations are required to establish the biological significance of these phenomena...
  44. ncbi Effects of sodium selenite on some biochemical and hematological parameters of rainbow trout (Oncorhynchus mykiss Walbaum, 1792) exposed to Pb2+ and Cu2+
    Burhan Ates
    Department of Chemistry, Inonu University, Malatya, 44280, Turkey
    Fish Physiol Biochem 34:53-9. 2008
    ....
  45. ncbi Influence of diets supplemented with vitamins C and E on pirarucu (Arapaima gigas) blood parameters
    Jaqueline Inês Alves de Andrade
    Aquaculture Department, INPA Instituto Nacional de Pesquisas da Amazônia, Av Andre Araujo, 2936, P O Box 478, Manaus, AM, 69060 001, Brazil
    Comp Biochem Physiol A Mol Integr Physiol 146:576-80. 2007
    ..Our results suggest that 800 and 1200 mg AA kg-1 are probably the most suitable concentrations for pirarucu diets, although high vitamin E diets are not necessary for quantitative leucocyte increases for this species...
  46. ncbi The effect of repeated acute mental stress on habituation and recovery responses in hemoconcentration and blood cells in healthy men
    Katharina Mischler
    Institute for Behavioral Sciences, Federal Institute of Technology, Zurich, Switzerland
    Life Sci 77:1166-79. 2005
    ..Plasma volume shift accompanying stress affects the time course of stress polycytosis...
  47. ncbi Evaluation of the effects of serial phlebotomy on the transcriptome of major tissues and on the response to toxicants in rats
    Eric A G Blomme
    Department of Cellular, Molecular and Exploratory Toxicology, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL, USA
    Toxicol Lett 176:138-48. 2008
    ....
  48. ncbi The evaluation of coagulation profiles in calves with suspected septic shock
    K Irmak
    Department of Internal Medicine, Faculty of Veterinary Medicine, University of Selcuk, Konya, Turkey
    Vet Res Commun 30:497-503. 2006
    ..The results of this study indicate that DIC might be a significant risk factor for mortality in calves with suspected septic shock...
  49. ncbi Exertional Rhabdomyolysis during a 246-km continuous running race
    Katerina P Skenderi
    Laboratory of Nutrition and Clinical Dietetics, Department of Nutrition and Dietetics, Harokopio University, Athens, Greece
    Med Sci Sports Exerc 38:1054-7. 2006
    ..To evaluate the effect of continuous, moderate-intensity ultra-endurance running exercise on skeletal muscle and hepatic damage, as indicated by serum enzyme activity measured immediately following the race...
  50. ncbi Erythropoietic response and hematological parameters in the catfish Clarias albopunctatus exposed to sublethal concentrations of actellic
    B O Mgbenka
    Fisheries and Hydrobiology Research Unit, Department of Zoology, University of Nigeria, Nsukka, Nigeria
    Ecotoxicol Environ Saf 62:436-40. 2005
    ..3, 0. 5, 0.8, and 1.0microg/L) of actellic for 18 days in a static bioassay system. The hemoglobin, erythrocyte count, hematocrit, and leucocyte counts were affected by actellic...
  51. ncbi Prevention of garlic-induced hemolytic anemia using some tropical green leafy vegetables
    Ganiyu Oboh
    Biochemistry Department, Federal University of Technology, Akure, Nigeria
    J Med Food 7:498-501. 2004
    ..5 fL). This therefore implies that garlic could induce hemolytic anemia in rats. However, such anemia could be prevented by some tropical green leafy vegetables such as A. cruentus, B. alba, and O. gratissimum...
  52. ncbi [Effect of bethametasone on blood cell count and C-reactive protein in patients with threatened preterm delivery]
    Nikola Niewegłowska
    II Katedra i Klinika Połoznictwa i Ginekologii, Akademii Medycznej w Warszawie
    Med Wieku Rozwoj 7:261-70. 2003
    ..Conclusions: Intramuscular administration of 12 mg betamethasone per day caused decrease of the RBC, HGB and HCT account and elevation of the WBC and neutrophil count. All these parameters normalized after about 7 days...
  53. ncbi Evaluation of erythropoiesis in protein energy malnutrition
    A el-Nawawy
    Department of Paediatrics, Faculty of Medicine, University of Alexandria, Alexandria, Egypt
    East Mediterr Health J 8:281-9. 2002
    ..The anaemia of protein energy malnutrition is due to mixed deficiencies resulting in ineffective erythropoiesis despite an increased level of erythropoietin...
  54. ncbi Effect of zinc supplementation on hematological parameters in athletes
    Mehmet Kilic
    School of Physical Education and Sports, Meram School of Medicine, Selcuk University, Konya Turkey
    Biol Trace Elem Res 100:31-8. 2004
    ..005) and after (p<0.05) exercise. These results suggest that zinc supplementation has a positive effect on hematological parameters in athletes...
  55. ncbi The influence of dietary vitamin C and E supplementation on the physiological response of pirarucu, Arapaima gigas, in net culture
    Glauber Cruz de Menezes
    Department of Aquaculture, INPA Amazonian National Research Institute, Av Andre Araujo, 2936, P O Box 478, Manaus, AM 69069 001, Brazil
    Comp Biochem Physiol A Mol Integr Physiol 145:274-9. 2006
    ..gigas immunological status. Red blood cell indices and immune system indicators showed no synergistic effect between the vitamins after supplementing the A. gigas diet with alpha-T+AA...
  56. ncbi Pharmacological and haematological results of rat skin burn injury treatment with Cu(II)2(3,5-diisopropylsalicylate)4
    Margarita H Malakyan
    Sector of Radiation Medicine and Burns, Center of Traumatology, Orthopedics, Burns and Radiology, Ministry of Health, Republic of Armenia, P O Box 25, Davidashen, Yerevan, Armenia 375108
    Inflammopharmacology 12:321-51. 2004
    ....
  57. ncbi Experimental concurrent infection of Afar breed goats with Oestrus ovis (L1) and Haemonchus contortus (L3): interaction between parasite populations, changes in parasitological and basic haematological parameters
    H T Yacob
    Department of Pathology and Parasitology, Faculty of Veterinary Medicine, Addis Ababa University, P O Box 34, Debre Zeit, Ethiopia
    Exp Parasitol 120:180-4. 2008
    ..05) in FEC, worm burden, fecundity and female worm length was revealed in group OH animals compared to the mono-infected animals (group H). This was associated with eosinophilia and reduced packed cell volume...
  58. ncbi Hematology and serum biochemistry of Holstein dairy calves: age related changes and comparison with blood composition in adults
    M Mohri
    Department of Clinical Sciences, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran
    Res Vet Sci 83:30-9. 2007
    ....
  59. ncbi Specific activities of poetam preparation (superlow-doses of antibodies to erythropoietin) and recombinant erythropoietin
    A M Dygai
    Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences
    Bull Exp Biol Med 142:320-3. 2006
    ..The effect of Recormon manifested immediately after injection, while the effect of Poetam was somewhat delayed, but more lasting (due to activation of host erythropoietin system)...
  60. ncbi Clinical pathologic alterations associated with subcutaneous administration of recombinant human interleukin-4 to cynomolgus monkeys
    K A Gossett
    Department of Toxicology, Sterling Winthrop Pharmaceuticals Research Division, Rensselaer, New York 12144
    Toxicol Pathol 21:46-53. 1993
    ..Based on data obtained after the 14-day recovery period, the clinical pathologic changes associated with rhuIL-4 administration were considered to be reversible...
  61. ncbi In vitro quality of red blood cells (RBCs) collected by multicomponent apheresis compared to manually collected RBCs during 49 days of storage
    Susanne M Picker
    Transfusion Medicine, University of Cologne, Cologne, Germany
    Transfusion 47:687-96. 2007
    ..This study's aim was to evaluate quality of apheresis-derived RBCs (ARBCs) collected as single units along with platelets (RBC-Ps) or double units (2-RBCs) with four different apheresis systems...
  62. ncbi Emblica officinalis (Linn.) fruit extract provides protection against radiation-induced hematological and biochemical alterations in mice
    Inder Singh
    Radiation and Cancer Biology Laboratory, Department of Zoology, University of Rajasthan, Jaipur, India
    J Environ Pathol Toxicol Oncol 25:643-54. 2006
    ..The results from the present study suggest that E. officinalis pretreatment provides protection against irradiation to Swiss albino mice...
  63. ncbi Effect of petroleum products inhalation on some haematological indices of fuel attendants in Calabar metropolis, Nigeria
    A M Okoro
    Department of Physiology, College of Medical Sciences, University of Calabar, Calabar, Cross River State, Nigeria
    Niger J Physiol Sci 21:71-5. 2006
    ..These results indicate that the petroleum fumes cause a reduction in haematological indices which worsens with prolonged exposure...
  64. ncbi Effect of increased dietary protein and decreased dietary carbohydrate on performance and body composition in racing Greyhounds
    R C Hill
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610-0126, USA
    Am J Vet Res 62:440-7. 2001
    ..Improved performance attributed to feeding meat to racing Greyhounds apparently is not attributable to increased dietary protein and decreased dietary carbohydrate...
  65. ncbi Short term evaluation of material blood compatibility using a microchannel array
    Kimi Kurotobi
    Biomaterials Center, National Institute for Materials Science NIMS, 1 1, Namiki, Tsukuba, Ibaraki 305 0044, Japan
    J Mater Sci Mater Med 18:1175-84. 2007
    ..We concluded that this method could be applied to evaluate initial blood compatibility of materials within several minutes in vitro...
  66. ncbi The effect of Cannabis sativa L. (hemp seed) on hematological parameters in guinea pigs
    Isaac Karimi
    Department of Physiology and Pharmacology, College of Veterinary Medicine, Urmia University, Urmia, Iran
    Cardiovasc Hematol Disord Drug Targets 7:288-90. 2007
    ..It is recommended that individuals who have anemia or immunity complication should not use hemp seed in their food preparation on regular basis...
  67. ncbi Physiopathological effects of the administration of chronic cyanide to growing goats--a model for ingestion of cyanogenic plants
    B Soto-Blanco
    Department of Pathology, School of Veterinary Medicine, , SP, Brazil
    Vet Res Commun 25:379-89. 2001
    ..Reabsorption vacuoles in follicular colloid and normocytic normochromic anaemia were observed in the experimental animals. Inhibition of peripheral conversion of T4 to T3 is suggested. However, no diabetogenic effects were observed...
  68. pmc Gametocytemia in Plasmodium vivax and Plasmodium falciparum infections
    F Ellis McKenzie
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Parasitol 92:1281-5. 2006
    ..falciparum patients with gametocytemia had similar platelet counts but lower red blood cell counts, hemoglobin levels, hematocrit levels, and higher lymphocyte counts than patients without gametocytemia...
  69. ncbi Hb Ft. Worth: a27Glu changed to Gly(B8). A variant present in unusually low concentration
    R G Schneider
    Biochim Biophys Acta 243:164-9. 1971
  70. ncbi Effect of high levels of dietary vitamin C on the blood responses of matrinxã (Brycon amazonicus)
    Elizabeth Gusmão Affonso
    Department of Aquaculture, INPA Amazonian National Research Institute, Av Andre Araujo, 2936, P O Box 478, Manaus, AM, 69 060 001, Brazil
    Comp Biochem Physiol A Mol Integr Physiol 147:383-8. 2007
    ..The physiological profile and the growth performance of matrinxã suggest that diet supplemented with 800 mg AA kg(-1) can improve its performance and increase the survival rate...
  71. ncbi [A programmed autologous transfusion. A study of 47 patients]
    Jalel Gargouri
    Centre régional de transfusion sanguine de Sfax
    Tunis Med 80:616-21. 2002
    ..1%) and of the rate of platelets (average increase of 29,324 platelets/mm3). On the other hand, a transfusional complement by the concentrated homologous red corpuscles was necessary for 2 patients (2/40)...
  72. ncbi Evaluation of factors that can modify platelet-rich plasma properties
    Miguel Gustavo Setúbal Andrade
    Bahia Foundation for Science Development and Postgraduate Program in Immunology, Bahia Federal University, Bahia, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:e5-e12. 2008
    ..The aim of this article is to discuss a protocol for obtaining platelet-rich plasma (PRP) and evaluate which factors, derived from its preparation method and from whole blood, modify PRP cytometry and coagulation time...
  73. ncbi Activation of natural killer cell function in recreational athletes with paraplegia during a wheelchair half-marathon race
    Kazunari Furusawa
    Kibikogen Rehabilitation Center for Employment Injuries, Okayama ken, Japan
    Arch Phys Med Rehabil 84:706-11. 2003
    ..To investigate a part of the immune homeostasis in recreational athletes with spinal cord injury (SCI) during and after a wheelchair half-marathon race...
  74. ncbi Hematologic values for tule elk (Cervus elaphus nannodes)
    Susan E Shideler
    Institute of Toxicology and Environmental Health, School of Veterinary Medicine, University of California, Davis, California 95616, USA
    J Wildl Dis 38:589-97. 2002
    ..Differences between capture groups were assessed. Greatest differences were detected between yearling bulls and cows in December 1998 which may be a reflection of age and reproductive status...
  75. ncbi [Hematology]
    E G Beck
    Hygiene Institut,
    Zentralbl Bakteriol Mikrobiol Hyg B 185:250-7. 1987
    ..When comparing the children from the control area Freiburg, a slight increase in the number of erythrocytes and the haemoglobin content was detected with increasing height as an adaptive reaction...
  76. ncbi Comparative assessment of the erythrocyte osmotic fragility and of haematological and plasma biochemical values in the Nigerian white Fulani and N'dama breeds of cattle
    F O Olayemi
    Department of Veterinary Physiology and Pharmacology, University of Ibadan, Ibadan, Nigeria
    Trop Anim Health Prod 34:181-7. 2002
    ....
  77. ncbi Effect of preexisting FeLV infection or FeLV and feline immunodeficiency virus coinfection on pathogenicity of the small variant of Haemobartonella felis in cats
    Jeanne W George
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA
    Am J Vet Res 63:1172-8. 2002
    ..To investigate the effects of preexisting FeLV infection or FeLV and feline immunodeficiency (FIV) coinfection on the pathogenicity of the small variant of Haemobartonella felis (Hfsm, California variant) in cats...
  78. ncbi Hematologic and serum biochemical changes in Salmonella ser Typhimurium-infected calves
    Renato L Santos
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station 77843 4467, USA
    Am J Vet Res 63:1145-50. 2002
    ..To evaluate hematologic and serum biochemical changes in Salmonella ser Typhimurium-infected calves...
  79. ncbi Comparative chronic toxicity and carcinogenicity of acrylonitrile by drinking water and oral intubation to Spartan Sprague-Dawley rats
    Frederick R Johannsen
    Environmental, Safety and Health, Solutia Inc, 575 Maryville Center Drive, St Louis, MO 63141, USA
    Toxicol Lett 132:197-219. 2002
    ..Small, sometimes statistically significant, reductions in hemoglobin, hematocrit and erythrocyte count were observed in male and female rats in both high dose (10 mg/kg per day intubation and 100 ppm drinking ..
  80. ncbi Nutritional status of patients hospitalised in Poland
    J Dzieniszewski
    Department of Dietetic and Nutrition in Hospital with Clinic of Metabolic Diseases and Gastroenterology, National Food and Nutrition Institute, Powslnska 61 63 Warsaw, Poland
    Eur J Clin Nutr 59:552-60. 2005
    ..Screening and extended assessment of the nutritional status of patients on admission and on discharge from hospital were carried out...
  81. ncbi With time changes of T-lymphocytes after Babesia infection in mice pretreated with Toxoplasma lysate antigen
    M Sato
    Department of Veterinary Clinical Radiology, Obihiro University, Japan
    Zentralbl Bakteriol Mikrobiol Hyg A 264:435-45. 1987
    ..The rates of decrease in the erythrocyte count, hemoglobin concentration, and hematocrit value 10 days after inoculation, as compared with the counterparts ..
  82. ncbi [Anemia in chronic renal insufficiency--case report]
    M Popovic
    Sluzba za unutrasnje bolesti, Zdravstveni centar Dr Gere Istvan, Senta
    Med Pregl 52:279-81. 1999
    ..It is applied subcutaneously and intravenously, whereas the dosage and length of treatment are individual...
  83. ncbi Effects of feeding Fusarium verticillioides (formerly Fusarium moniliforme) culture material containing known levels of fumonisin B1 in Japanese quail (Coturnix coturnix japonica)
    R K Asrani
    Department of Veterinary Pathology, Dr CG Negi College of Veterinary and Animal Sciences, CSK Himachal Pradesh Agricultural University, Palampur, India
    Poult Sci 85:1129-35. 2006
    ..Fumonisin feeding significantly increased hemoglobin, packed cell volume, total erythrocyte count, and total leukocyte count...
  84. ncbi Micrococcus luteus and Pseudomonas species as probiotics for promoting the growth performance and health of Nile tilapia, Oreochromis niloticus
    Azza M Abd El-Rhman
    Fish Disease Department, Central Laboratory for Aquaculture Research CLAR, Abbassa, Abu Hammad, Sharkia, Egypt
    Fish Shellfish Immunol 27:175-80. 2009
    ..M. luteus enhanced the fish growth and health. It is recommended to use M. luteus as a probiotic in vivo, while Pseudomonas species showed probiotic effects in vitro only...
  85. ncbi Fetal and juvenile animal hemorheology
    U Windberger
    Core Unit for Biomedical Research, Medical University of Vienna, General Hospital, Austria
    Clin Hemorheol Microcirc 32:191-7. 2005
    ..10/1.10/1.05; cat: 1.27/1.39 mPa s), which was associated with a low plasma protein concentration and a low erythrocyte count despite a high erythrocyte volume...
  86. ncbi [Lead exposure in highway toll-booth workers]
    Azra Hursidić-Radulović
    Arh Hig Rada Toksikol 54:133-40. 2003
    ..282, P < 0.05), EP inversely correlated with erythrocyte count (r = -0.253, P < 0.05), and ALAD positively correlated with MCHC (r = 0.306, P < 0...
  87. ncbi Fetal tobacco syndrome and perinatal outcome
    Dubravko Habek
    Division of Perinatology, Department of Obstetrics and Gynaecology, Clinical Hospital Osijek, Croatia
    Fetal Diagn Ther 17:367-71. 2002
    ..The aim of this study was to evaluate perinatal outcome in newborns of mothers who are smokers...
  88. ncbi Some aspects of hemostasis in kidney transplant recipients maintained on cyclosporine, azathioprine, and prednisone in comparison to patients treated with cyclosporine and prednisone
    J Malyszko
    Department of Nephrology and Transplantology, Medical University, 15 540 Bialystok, Zurawia 14, Poland
    Transplant Proc 35:2940-2. 2003
    ..086), the groups did not differ with regard to age, BMI, erythrocyte count, hematocrit, leukocyte count, creatinine clearance, alanine and asparagine aminotransferase activities mean ..
  89. ncbi Chronic toxicity of di(2-ethylhexyl)phthalate in rats
    R M David
    Health and Environment Laboratories, Eastman Kodak Company, Rochester, New York 14652 6272, USA
    Toxicol Sci 55:433-43. 2000
    ..b>Erythrocyte count, hemoglobin, and hematocrit values for the 12,500-ppm group were significantly lower than controls at nearly ..
  90. ncbi Elevated levels of human beta-defensin 2 and human neutrophil peptides in systemic lupus erythematosus
    S Vordenbäumen
    Department of Endocrinology, Diabetology, and Rheumatology, Heinrich Heine University Dusseldorf, Germany
    Lupus 19:1648-53. 2010
    ..In order to explore whether these defensins may have a role in the pathogenesis of systemic lupus erythematosus (SLE), we sought to determine whether altered expression can be found in SLE patients...
  91. pmc Effects of acepromazine on the stress response in Southern chamois (Rupicapra pyrenaica) captured by means of drive-nets
    Jorge R Lopez-Olvera
    Servei d Ecopatologia de Fauna Salvatge, Facultat de Veterinària Edifici V, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Can J Vet Res 71:41-51. 2007
    ..The lower heart-rate variability, temperature, erythrocyte count, hemoglobin concentration, packed cell volume (PCV), and serum creatine kinase activity in the animals ..
  92. ncbi Microbial levan in the diet of Labeo rohita Hamilton juveniles: effect on non-specific immunity and histopathological changes after challenge with Aeromonas hydrophila
    S K Gupta
    Department of Fish Nutrition and Biochemistry, Central Institute of Fisheries Education, Mumbai, India
    J Fish Dis 31:649-57. 2008
    ..An increasing trend for total erythrocyte count was observed with increasing level of dietary levan...
  93. ncbi Influence of bromfenvinphos alone, and in mixture with methoxychlor, on levels of gamma-glutamyl transpeptidase, ceruloplasmin and cholesterol in the blood plasma of laboratory mice
    K I Zaleska-Freljan
    Department of Vertebrate Animal Physiology, University of Warsaw, Poland
    Pol J Pharmacol 45:309-16. 1993
    ..The hematocrit value, the erythrocyte count and the weights of the liver, spleen, heart, kidney and gonads were also measured after the end of treatment...
  94. ncbi Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on production and metabolism in broilers
    H V L N Swamy
    Department of Animal and Poultry Science, University of Guelph, ON, Canada
    Poult Sci 81:966-75. 2002
    ..The feeding of contaminated grains in the finisher period also caused significant linear increases in blood erythrocyte count and serum uric acid concentration and a significant linear decline in the serum lipase activity...
  95. ncbi Hematological effects in F344 rats and B6C3F1 mice during the 13-week gavage toxicity study of methylene blue trihydrate
    M R Hejtmancik
    Battelle, 505 King Avenue, Columbus, Ohio 43201, USA
    Toxicol Sci 65:126-34. 2002
    ..bodies and the development of anemia that was characterized by a decrease in hemoglobin, hematocrit, and erythrocyte count. Splenomegaly was apparent in all treated mice and in the 100 mg/kg (males only) and 200 mg/kg rats at ..
  96. ncbi Hematologic changes associated with the appearance of eccentrocytes after intragastric administration of garlic extract to dogs
    K W Lee
    Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
    Am J Vet Res 61:1446-50. 2000
    ..To determine whether dogs given garlic extract developed hemolytic anemia and to establish the hematologic characteristics induced experimentally by intragastric administration of garlic extract...
  97. ncbi Erythropoietic activity of Asteracantha longifolia (Nees.) in rats
    Rajesh Singh Pawar
    VNS Institute of Pharmacy, Vidhya Vihar, Neelbud, Bhopal, MP, India
    J Ethnopharmacol 129:280-2. 2010
    ..Family-Acanthaceae) is a wild herb commonly used in traditional ayurvedic medicine as Kokilaaksha and the Unani drug as Talimakhana in India and Srilanka for various medicinal uses as aphrodisiac, tonic, sedative and blood diseases etc...
  98. ncbi Effect of diallyl trisulfide-rich garlic oil on blood coagulation and plasma activity of anticoagulation factors in rats
    Kung Chi Chan
    Department of Food and Nutrition, Providence University, Sha Lu, Taichung, Taiwan, ROC
    Food Chem Toxicol 45:502-7. 2007
    ..05), and affected the levels of several hematological parameters such as erythrocyte count, hemoglobin and platelets (P<0.05)...
  99. ncbi The erythrocyte indices of neonates, defined using data from over 12,000 patients in a multihospital health care system
    R D Christensen
    Intermountain Healthcare, Ogden, UT 84403, USA
    J Perinatol 28:24-8. 2008
    ..originally reported using hand-calculated values, based on a centrifuge-spun hematocrit, a counting-chamber erythrocyte count and a hemoglobin concentration measured by any number of hemoglobinometry methods...
  100. ncbi Flow cytometric determination of neutrophil respiratory burst activity in workers exposed to formaldehyde
    M Lyapina
    Department of Hygiene and Medical Ecology, Medical University, 15 Dimitar Nestorov St, 1431, Sofia, Bulgaria, E mail
    Int Arch Occup Environ Health 77:335-40. 2004
    ..The aim of the study was to investigate neutrophil respiratory burst activity (NRBA) in workers who were occupationally exposed to formaldehyde...
  101. ncbi [Effects of nCPAP therapy on the blood picture in patients with obstructive sleep apnea]
    B Sanner

    Pneumologie 49:413-7. 1995
    ..001), the erythrocyte count from 5.02 +/- 0.42/pl to 4.79 +/- 0.51/pl (p < 0.001), and hematocrit from 45.4 +/- 3.1% to 43.1 +/- 4...

Research Grants63

  1. GENETIC DETERMINANTS OF CHOLESTEROL GALLSTONES IN MICE
    Beverly Paigen; Fiscal Year: 2005
    ..Identifying the full range of QTLs that lead to gallstone disease in the mouse will position the field of cholesterol gallstone research to take advantage of the large genomic sequencing efforts currently underway. ..
  2. Xenobiotics, Lipid Peroxidation and Autoimmunity
    M Firoze Khan; Fiscal Year: 2006
    ..abstract_text> ..
  3. SPLENIC TOXICITY OF ANILINE
    M Firoze Khan; Fiscal Year: 2010
    ..These studies will elucidate the mechanisms of aniline-induced splenic toxicity, and will be important in devising strategies to prevent toxicity, and in risk assessment of aniline and other structurally-related aromatic amines. ..
  4. Vanadocenes as a New Class of Spermicidal Drugs
    OSMOND D CRUZ; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  5. Mammalian Lactoferrin Receptors: Structure and Function
    Bo Lonnerdal; Fiscal Year: 2007
    ..Overall, our understanding of the physiological significance of Lf and its receptor will be increased. ..
  6. Pain Mechanisms and the Development of Analgesics
    Tony Yaksh; Fiscal Year: 2006
    ..g. COX2 inhibitors, GABApentin, ziconotide) and failures (NK1 antagonist). [unreadable] [unreadable] [unreadable]..
  7. IN VIVO DYNAMIC OF BETA-CAROTENE METABOLISM IN HUMANS
    Andrew Clifford; Fiscal Year: 2006
    ....
  8. Advanced Techniques for Assessing Osteoarthritis in Rats
    Mark Brezinski; Fiscal Year: 2008
    ..3. Examining the Combination of OCT with the Microawl Therapeutic Technique in a Surgical Rat Model of OA. 4. Examining the Combination of OCT with a Pharmaceutical Intervention in Surgical Rat Model of OA. ..
  9. Phase II SBIR: WHI-07: A Novel Dual-Function Microbicide
    OSMOND D CRUZ; Fiscal Year: 2005
    ....
  10. Omega-3 Fatty Acids in the Treatment of Depression
    David Mischoulon; Fiscal Year: 2005
    ..It is hoped that this project will provide the critical fund of basic knowledge and practical experience necessary to aid the candidate in becoming an independent investigator. ..
  11. NEUROBIOLOGY OF PAIN
    Tony Yaksh; Fiscal Year: 2005
    ..The complexity of the problems and the diversity of the training approaches emphasize that the training received by these fellows will provide a broad base of knowledge relevant to wide areas of neurobiology. ..
  12. Spinal Galanin and its Receptors in Pain Processing
    Tony Yaksh; Fiscal Year: 2005
    ..We believe the outcome of these studies will provide direct evidence for the role played by this spinal peptidergic system in pain and point to the development of novel anti-hyperpathic agents. ..
  13. Optical Coherence Tomography for Microsurgical Guidance
    Mark Brezinski; Fiscal Year: 2005
    ..Use structural, polarization, and spectroscopic data to identify sensor vs motor nerves, and 7. guide epineural nerve repair with OCT guidance. ..
  14. Biobehavioral-Cytokine Interactions in Ovarian Cancer
    Susan Lutgendorf; Fiscal Year: 2007
    ..Findings will have implications for innovative behavioral and pharmacological intervention strategies for ovarian cancer patients. ..
  15. ALCOHOL, HIV, AND THE BRAIN
    Adolf Pfefferbaum; Fiscal Year: 2006
    ..Specific Aim 3: To establish cross-sectional and longitudinal within-subject relationships among nueroimaging, neuropsychological, and clinical measures. ..
  16. Quantitation of Tocopherol Metabolism in Humans
    ANDREW JOSEPH CLIFFORD; Fiscal Year: 2010
    ..Particular attention will be directed to the absorption phase. The results are expected to provide information about vitamin E biopotency and eventually improved Dietary Recommendations. ..
  17. NORMAL AGING OF BRAIN STRUCTURE AND FUNCTION
    EDITH VIONI SULLIVAN; Fiscal Year: 2010
    ..Initiate longitudinal 4-year follow-up data collection to test hypotheses regarding selective accelerated deterioration of frontally-based brain systems in normal aging. ..
  18. Lung Perfusion Heterogeneity and Mechanisms of Edema
    Susan R Hopkins; Fiscal Year: 2010
    ..abstract_text> ..
  19. Omega-3 Fatty Acids for Treatment of Major Depression
    David Mischoulon; Fiscal Year: 2010
    ..e. integrates biological findings with treatment in order to have a direct impact on the clinical practice of psychiatry. ..
  20. Identification and Treatment Of Unstable Plaque with OCT
    Mark Brezinski; Fiscal Year: 2009
    ..In addition, we will in parallel attempt to further improve the rabbit hemorrhagic plaque model by inducing angiogenesis, the factor which may ultimately be the trigger of many plaque ruptures. ..
  21. CEREBELLAR STRUCTURE AND FUNCTION IN ALCOHOLISM
    Edith Sullivan; Fiscal Year: 2008
    ..abstract_text> ..
  22. Mechanism & Efficacy of Assessing Osteoarthritis by OCT
    Mark Brezinski; Fiscal Year: 2009
    ..5. In patients undergoing microfracture during arthroscopy for the treatment of localized OA, OCT imaging will be performed of adjacent articular cartilage. ..
  23. Rapid Screen for Genotoxicants, Chemoprotectors, and Radioprotectors
    Stephen Dertinger; Fiscal Year: 2008
    ..In addition, this assay can be used to investigate agents designed to ameliorate the effects of radiation exposure, e.g. biological response modifiers. [unreadable] [unreadable] [unreadable] [unreadable]..
  24. Attentional Dysfunction in Children with Phenylketonuria
    Georgianne Arnold; Fiscal Year: 2008
    ....
  25. High Throughput Radiation Biodosimetry
    Stephen Dertinger; Fiscal Year: 2007
    ..We propose to develop such a radiation biodosimetry assay based on the extremely high analysis rates that are possible with flow cytometry instrumentation. [unreadable] [unreadable] [unreadable]..
  26. Optical Coherence Tomography for Pulmonary Circulation
    Mark Brezinski; Fiscal Year: 2005
    ..Development of an OCT Imaging Catheter, Aim 2. Assessing the Pulmonary Veins Ablation in an Animal Model, Aim 3. Vascular Assessments In Vitro, Aim 4. OCT Elastography and Aim 5. OCT Imaging will be performed in an Animal Model of PTN. ..
  27. PAIN EVOKED RELEASE OF AMINO ACIDS AND PROSTANOIDS
    Tony Yaksh; Fiscal Year: 2005
    ....
  28. NOVEL CONTRACEPTIVES WITH ANTI-HIV ACTIVITY
    OSMOND D CRUZ; Fiscal Year: 2001
    ..The preclinical data on in vivo efficacies of WHI-05 and WHI-07 will be essential to further explore the utility of these novel drugs for clinical studies in human patients. ..
  29. FLP-102: Rationally Engineered Antiviral Protein
    OSMOND D CRUZ; Fiscal Year: 2003
    ..The preclinical data on FLP-102 will be essential to further explore the utility of this novel recombinant PAP mutant for Phase II. ..
  30. IMPROVING THE DIAGNOSTIC POTENTIAL OF OCT FOR VULNERABLE
    Mark Brezinski; Fiscal Year: 2002
    ..abstract_text> ..
  31. FACSVantage SE Sorting Flow Cytometer
    Jane Barker; Fiscal Year: 2002
    ..Funds are requested to purchase the FACSVantage SE and the optional equipment for TJL's Flow Cytometry Service. This will provide a cost-effective way to fill an urgent need of TJL's principal investigators. ..
  32. Healing Touch and Immunity in Advanced Cervical Cancer
    Susan Lutgendorf; Fiscal Year: 2002
    ....
  33. INDICES OF BIOTIN NUTRITION
    Donald Mock; Fiscal Year: 2001
    ..4) Whether biotin deficiency of similar severity to that observed either early or late in human gestation causes increased rates of fetal malformation in the mouse. 5) The enzyme(s) responsible for biotin beta-oxidation. ..
  34. TUMOR NECROSIS FACTOR INVOLVEMENT IN FUMONISIN TOXICITY
    RAGHUBIR SHARMA; Fiscal Year: 2001
    ..Results will help in defining the mechanism(s) of fumonisin toxicity, causes of species-specificity, and provide a better appraisal of risk in humans, including modification of fumonisin response by gram-negative infections. ..
  35. Measuring Cytogenetic Damage in Human Blood
    Stephen Dertinger; Fiscal Year: 2003
    ..abstract_text> ..
  36. PHI-443: Novel Non-Spermicidal Anti-HIV Microbicide
    OSMOND D CRUZ; Fiscal Year: 2003
    ..Specific Aims 1 and 2 may provide the foundation for the clinical development of PHI-443 in Phase II studies as a safe, effective broad-spectrum anti-HIV microbicide without conception-inhibiting functions. ..
  37. ALCOHOL, HIV, AND THE BRAIN
    Adolf Pfefferbaum; Fiscal Year: 2004
    ..Specific Aim 3: To establish cross-sectional and longitudinal within-subject relationships among nueroimaging, neuropsychological, and clinical measures. ..
  38. GENETICS OF HEART AND KIDNEY DAMAGE IN HYPERTENSION
    Christian Deschepper; Fiscal Year: 2004
    ..abstract_text> ..
  39. In vivo mutation assay based on pig-a locus
    Stephen Dertinger; Fiscal Year: 2004
    ....
  40. REFERENCE LABORATORY TO EVALUATE THERAPIES FOR SCD
    Toshio Asakura; Fiscal Year: 2004
    ..This enhances the likelihood of finding potentially clinically useful compounds. ..
  41. Healing Touch, Immunity, and Fatigue in Breast Cancer
    Susan Lutgendorf; Fiscal Year: 2004
    ....
  42. Stampidine: A Novel Broad-Spectrum Anti-HIV Microbicide
    OSMOND D CRUZ; Fiscal Year: 2005
    ..Specific Aims 1 and 2 may provide the foundation for the clinical development of STAMP in Phase II studies as a safe, effective broad-spectrum anti-HIV microbicide without conception-inhibiting functions. ..
  43. GENETIC ENGINEERING OF CELLS FROM ANEMIC ANIMALS
    Jane Barker; Fiscal Year: 2003
    ..abstract_text> ..
  44. Quantitation of In Vivo Human Lutein Metabolism
    ANDREW JOSEPH CLIFFORD; Fiscal Year: 2010
    ..Therefore, the purpose of this study is to determine how the human body uses lutein and other related compounds. ..
  45. Characterization of Toxicity with Spinal Opiates
    Tony L Yaksh; Fiscal Year: 2010
    ..The present studies aim to define the mechanisms of granuloma formation and point to specific methods to prevent granuloma formation, which will increase the utility and reduce the risks of this important pain therapy. ..
  46. METVAN: A Novel Anticancer Agent
    OSMOND D CRUZ; Fiscal Year: 2003
    ..The knowledge gained from these studies described under Specific Aims 1-2 is expected to facilitate the design of innovative treatment regimens employing METVAN for metastatic breast cancer and brain tumor patients. ..
  47. Automation of the vitro Micronucleus Assay
    Stephen Dertinger; Fiscal Year: 2004
    ..abstract_text> ..
  48. PHI 346: A Novel Dual-Function Microbicide
    OSMOND D CRUZ; Fiscal Year: 2003
    ..Following successful completion of the Phase I in vivo efficacy studies, gel formulation of PHI-346 will be further explored as a vaginal dual-function microbicide in Phase II. ..
  49. Mouse Models for Heart, Lung and Blood Disease
    LUANNE PETERS; Fiscal Year: 2007
    ..New mouse models will be cryo-preserved in order to maintain their availability. Provision are likewise to maintain all JAX PGA resources beyond the PGA program. ..
  50. Versatile Mutation Assay Platform
    Stephen Dertinger; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  51. CO POISONING IN THE CONTEXT OF A REPERFUSION INJURY
    Stephen Thom; Fiscal Year: 2003
    ..The research plan is aimed to test the hypothesis that immune responses and the associated oxidative stress cause neurological injuries. ..
  52. DYNAMIC AND KINETIC BEHAVIOR OF FOLATE METABOLISM
    Andrew Clifford; Fiscal Year: 2005
    ..We will determine the in vivo kinetic behavior of a tracer dose of folate in blood, urine, and stool. We will then compare the behavior of folate metabolism (functional endpoint) among the various genotypes. ..
  53. ORGANELLE MEMBRANES IN PLATELET STORAGE POOL DISEASE
    LUANNE PETERS; Fiscal Year: 2009
    ..Lung fibrosis typically leads to death in the 4th to 5th decades. This study is designed to identify the underlying genetic causes of HPS, which will provide avenues of research for potential therapies. ..
  54. CLONING AND CHARACTERIZATION OF ATH8
    Beverly Paigen; Fiscal Year: 2001
    ..Finally, the most compelling candidate gene will be tested by transgenic rescue of the phenotype or construction of a knockout with a resulting change in atherosclerosis phenotype. ..
  55. From QTL to Gene for HDL Cholesterol
    Beverly Paigen; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  56. GENETIC INTERACTIONS IN RED CELL MEMBRANE DISEASE
    LUANNE PETERS; Fiscal Year: 2003
    ....
  57. Identifying Genes Regulating HDL Cholesterol Levels
    Beverly Paigen; Fiscal Year: 2007
    ..The genes will be proved with the techniques of gene targeting and transgenics. Human homologue genes will be identified by comparative genomics. [unreadable] [unreadable]..
  58. Adducin and the Membrane Skeleton
    LUANNE PETERS; Fiscal Year: 2007
    ..Follow up studies will include electrocardiology and echocardiology. ..
  59. GENE EXPRESSION ARRAYS FOR HEART, LUNG AND BLOOD RESEARC
    Beverly Paigen; Fiscal Year: 2003
    ....
  60. Hemolytic Anemia: Models
    LUANNE PETERS; Fiscal Year: 2006
    ..5 isoform in the structure and assembly of the sarcoplasmic reticulum by an in vivo developmental study. ..
  61. Mouse Allergen-Specific IgG as a Biomarker of Exposure
    Beverly Paigen; Fiscal Year: 2006
    ....