residual volume

Summary

Summary: The volume of air remaining in the LUNGS at the end of a maximal expiration. Common abbreviation is RV.

Top Publications

  1. ncbi Pulmonary sarcoidosis. Correlation of expiratory high-resolution CT findings with inspiratory patterns and pulmonary function tests
    E Magkanas
    Department of Radiology, University Hospital of Crete, Stavrakia, Heraklion, Crete, Greece
    Acta Radiol 42:494-501. 2001
  2. ncbi Bronchoscopic lung-volume reduction with Exhale airway stents for emphysema (EASE trial): randomised, sham-controlled, multicentre trial
    P L Shah
    National Institute for Health Research Respiratory Biomedical Research Unit at Royal Brompton and Harefield NHS Foundation Trust, Imperial College, London, UK
    Lancet 378:997-1005. 2011
  3. ncbi The minimal important difference for residual volume in patients with severe emphysema
    Jorine E Hartman
    Dept of Pulmonary Diseases AA11, University Medical Center Groningen, PO Box 30001, 9700 RB Groningen, The Netherlands
    Eur Respir J 40:1137-41. 2012
  4. ncbi Bronchodilator response in residual volume in irreversible airway obstruction
    Anna Maria Balestra
    Pneumology, University Hospital Basel, Switzerland
    Swiss Med Wkly 138:251-5. 2008
  5. ncbi Pulmonary edema and hemoptysis after breath-hold diving at residual volume
    Peter Lindholm
    Centre for Environmental Physiology, Karolinska Institutet, 17177, Stockholm, Sweden
    J Appl Physiol (1985) 104:912-7. 2008
  6. pmc Preoperative estimation of residual volume for WHO grade II glioma resected with intraoperative functional mapping
    Emmanuel Mandonnet
    Department of Neurosurgery, Hopital de la Pitie Salpetriere, 75651 Paris, France
    Neuro Oncol 9:63-9. 2007
  7. ncbi Cystic fibrosis lung disease: when does it start, and how can it be prevented?
    Susanna A McColley
    J Pediatr 145:6-7. 2004
  8. ncbi High-resolution computed tomography in young patients with cystic fibrosis: distribution of abnormalities and correlation with pulmonary function tests
    Alan S Brody
    Department of Pediatrics, Children s Hospital and Medical Center, Cincinnati, Ohio 45229 3039, USA
    J Pediatr 145:32-8. 2004
  9. ncbi Early emphysema in patients with anorexia nervosa
    Harvey O Coxson
    Department of Radiology, Vancouver Coastal Health Research Institute Vancouver General Hospital, Vancouver, BC V5Z 1M9, Canada
    Am J Respir Crit Care Med 170:748-52. 2004
  10. ncbi Dual energy X-ray absorptiometry outcomes in male COPD patients after treatment with different glucocorticoid regimens
    Emile F Dubois
    Department of Pulmonary Diseases, Reinier de Graaf Groep Delft and Voorburg, The Netherlands
    Chest 121:1456-63. 2002

Detail Information

Publications240 found, 100 shown here

  1. ncbi Pulmonary sarcoidosis. Correlation of expiratory high-resolution CT findings with inspiratory patterns and pulmonary function tests
    E Magkanas
    Department of Radiology, University Hospital of Crete, Stavrakia, Heraklion, Crete, Greece
    Acta Radiol 42:494-501. 2001
    ..A significant correlation was found between AT extent at expiration, with residual volume-total lung capacity ratio and residual volume. CONCLUSION: AT is an additional HRCT finding in sarcoidosis...
  2. ncbi Bronchoscopic lung-volume reduction with Exhale airway stents for emphysema (EASE trial): randomised, sham-controlled, multicentre trial
    P L Shah
    National Institute for Health Research Respiratory Biomedical Research Unit at Royal Brompton and Harefield NHS Foundation Trust, Imperial College, London, UK
    Lancet 378:997-1005. 2011
    ..The aim of the EASE (Exhale airway stents for emphysema) trial was to evaluate safety and efficacy of airway bypass in people with severe homogeneous emphysema...
  3. ncbi The minimal important difference for residual volume in patients with severe emphysema
    Jorine E Hartman
    Dept of Pulmonary Diseases AA11, University Medical Center Groningen, PO Box 30001, 9700 RB Groningen, The Netherlands
    Eur Respir J 40:1137-41. 2012
    b>Residual volume (RV) measured by body plethysmography is a routine measurement in clinical pulmonary practice and is often an important outcome variable in clinical trials...
  4. ncbi Bronchodilator response in residual volume in irreversible airway obstruction
    Anna Maria Balestra
    Pneumology, University Hospital Basel, Switzerland
    Swiss Med Wkly 138:251-5. 2008
    ....
  5. ncbi Pulmonary edema and hemoptysis after breath-hold diving at residual volume
    Peter Lindholm
    Centre for Environmental Physiology, Karolinska Institutet, 17177, Stockholm, Sweden
    J Appl Physiol (1985) 104:912-7. 2008
    ..while breath-hold diving in a relatively safe environment, competitive breath-hold divers exhale to residual volume before diving in a swimming pool, thus compressing the chest even at depth of only 3-6 m...
  6. pmc Preoperative estimation of residual volume for WHO grade II glioma resected with intraoperative functional mapping
    Emmanuel Mandonnet
    Department of Neurosurgery, Hopital de la Pitie Salpetriere, 75651 Paris, France
    Neuro Oncol 9:63-9. 2007
    ..Because these tumors frequently invade functional areas, the preoperative estimation of the probable residual volume remains challenging...
  7. ncbi Cystic fibrosis lung disease: when does it start, and how can it be prevented?
    Susanna A McColley
    J Pediatr 145:6-7. 2004
  8. ncbi High-resolution computed tomography in young patients with cystic fibrosis: distribution of abnormalities and correlation with pulmonary function tests
    Alan S Brody
    Department of Pediatrics, Children s Hospital and Medical Center, Cincinnati, Ohio 45229 3039, USA
    J Pediatr 145:32-8. 2004
    ..To assess pulmonary abnormalities detected by high-resolution computed tomography (HRCT) in young children with cystic fibrosis (CF) and mild to moderate lung disease...
  9. ncbi Early emphysema in patients with anorexia nervosa
    Harvey O Coxson
    Department of Radiology, Vancouver Coastal Health Research Institute Vancouver General Hospital, Vancouver, BC V5Z 1M9, Canada
    Am J Respir Crit Care Med 170:748-52. 2004
    ..These data demonstrate that emphysema-like changes are present in the lungs of patients who are chronically malnourished...
  10. ncbi Dual energy X-ray absorptiometry outcomes in male COPD patients after treatment with different glucocorticoid regimens
    Emile F Dubois
    Department of Pulmonary Diseases, Reinier de Graaf Groep Delft and Voorburg, The Netherlands
    Chest 121:1456-63. 2002
    ..To compare bone mineral density (BMD) outcomes of patients who received continuous oral systemic glucocorticoids (GCs) with BMD outcomes of patients who received multiple GC courses, oral or IV...
  11. ncbi Short-term reproducibility of computed tomography-based lung density measurements in alpha-1 antitrypsin deficiency and smokers with emphysema
    S B Shaker
    Department of Respiratory Medicine, Gentofte Hospital, Hellerup, Denmark
    Acta Radiol 45:424-30. 2004
    ..To study the short-term reproducibility of lung density measurements by multi-slice computed tomography (CT) using three different radiation doses and three reconstruction algorithms...
  12. ncbi Comparison of lung volume measurements in individuals with spinal cord injury by two different methods
    Gregory J Schilero
    Spinal Cord Damage Research Center, The Bronx Veterans Affairs Medical Center, Bronx, New York 10468, USA
    J Spinal Cord Med 27:443-7. 2004
    ..The purpose of this study was to compare lung volume parameters obtained by whole body plethysmography with those determined by the commonly used nitrogen washout technique among individuals with SCI...
  13. ncbi Long-term pulmonary morbidity in survivors of congenital diaphragmatic hernia
    Daniel Trachsel
    Division of Respiratory Medicine, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Pediatr Pulmonol 39:433-9. 2005
    ..This should guide follow-up scheduling and should be taken into account for perioperative and critical care management...
  14. pmc Assessment of the alveolar volume when sampling exhaled gas at different expired volumes in the single breath diffusion test
    Renato Prediletto
    Institute of Clinical Physiology, National Research Council of Italy, Pisa, Italy
    BMC Pulm Med 7:18. 2007
    ..The aim of this study was to investigate the effects of the maldistribution of ventilation on the real estimate of alveolar volume and to evaluate some indicators suggestive of the presence of maldistribution of ventilation...
  15. ncbi Oxidative stress in patients with COPD and pulmonary hypertension
    Pavol Joppa
    Department of Respiratory Medicine and Tuberculosis, Faculty of Medicine, P J Safarik University and L Pasteur Teaching Hospital, Rastislavova 43, 041 90 Kosice, Slovakia
    Wien Klin Wochenschr 119:428-34. 2007
    ....
  16. ncbi Peak expiratory flow in children and adolescents with idiopathic scoliosis
    Ryszard Zaba
    Clinic Ward of Pediatrics, Medical University of Silesia
    Wiad Lek 56:552-5. 2003
    ..FEV1), residual volume (RV) and intrathoracic gas volume (ITGV). At the same time peak expiratory flow--PEF were determined...
  17. ncbi Lung-volume reduction surgery for severe emphysema: appraisal of its current status
    Terence K Trow
    Pulmonary Hypertension Center, Winthrop University Hospital, State University of New York at Stony Brook, Mineola, New York, USA
    Curr Opin Pulm Med 10:128-32. 2004
    ....
  18. ncbi Pharmacological approaches to stable chronic obstructive pulmonary disease
    Rachel Booker
    The National Respiratory Training Centre, Warwick, UK
    Br J Nurs 13:1130-4. 2004
    ..In turn this reduces disability, improves the patient's health-related quality of life and has the potential to reduce costs to the health service and to society...
  19. ncbi Deep breaths, methacholine, and airway narrowing in healthy and mild asthmatic subjects
    Emanuele Crimi
    Dipartimento di Medicina Interna, Universita di Genova, 16132 Genova, Italy
    J Appl Physiol (1985) 93:1384-90. 2002
    ..e., airway conductance, functional residual capacity, as well as flow and residual volume from partial forced expiration...
  20. ncbi Physiological characterization of variability in response to lung volume reduction surgery
    Edward P Ingenito
    Division of Pulmonary and Critical Care Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA
    J Appl Physiol (1985) 94:20-30. 2003
    ..women), spirometry [forced expiratory volume in 1 s (FEV(1)) and forced vital capacity (FVC)], lung volumes [residual volume (RV) and total lung capacity (TLC)], small airway resistance, recoil pressures, and respiratory muscle ..
  21. ncbi Diaphragm length during tidal breathing in patients with chronic obstructive pulmonary disease
    Robert B Gorman
    Prince of Wales Medical Research Institute and University of New South Wales, Sydney, Australia
    Am J Respir Crit Care Med 166:1461-9. 2002
    ..Diaphragm length was 20% shorter in patients at residual volume (413 and 536 mm in patients and control subjects, respectively) and FRC (381 and 456 mm, respectively), but ..
  22. ncbi [Lung function changes during anesthesia and thoracic surgery]
    Dennis R Bigler
    Anaestesiologisk afdeling, Amtssygehuset i Gentofte, DK 2900 Hellerup
    Ugeskr Laeger 165:232-5. 2003
    ..651 or 22% of predicted value) with lung resection and immediate extubation. A reduction in pulmonary complications after thoracic surgery from 25-30% down to 10-15% is also seen, depending on age and preoperative lung function...
  23. ncbi An automated approach to quantitative air trapping measurements in mild cystic fibrosis
    Michael L Goris
    Division of Nuclear Medicine Radiology, Stanford University, CA 94305, USA
    Chest 123:1655-63. 2003
    ..To automatically derive the degree of air trapping in mild cystic fibrosis (CF) disease from high-resolution CT (HRCT) data, and to evaluate the discriminating power of the measurement...
  24. ncbi Spinal stiffness changes throughout the respiratory cycle
    D Shirley
    School of Physiotherapy, Faculty of Health Sciences, Univ of Sydney, P O Box 170, Lidcombe, Sydney NSW 1825, Australia
    J Appl Physiol (1985) 95:1467-75. 2003
    ..The results indicate that changes in trunk muscle activity and IAP with respiratory efforts modulate spinal stiffness. In addition, the diaphragm may augment spinal stiffness via attachment of its crural fibers to the lumbar vertebrae...
  25. ncbi Lung function in children with diabetes mellitus
    Salvatore Cazzato
    Department of Pediatrics, University of Bologna, S Orsola Malpighi Hospital, Bologna, Italy
    Pediatr Pulmonol 37:17-23. 2004
    ..28, P = 0.001, respectively). These differences also existed in the group investigated at onset of diabetes. Residual volume (RV) and RV/total lung capacity ratio (RV/TLC) were significantly higher in the whole group of patients with ..
  26. pmc Physiologic basis for improved pulmonary function after lung volume reduction
    Henry E Fessler
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Proc Am Thorac Soc 5:416-20. 2008
    ..In emphysema, elevation in residual volume relative to total lung capacity reduces forced expiratory volumes, increases inspiratory effort, and impairs ..
  27. ncbi [Evaluation of a new method for detection of obstructive disease in children asthma: the negative expiratory pressure (NEP)]
    P Forey
    Service de Pediatrie, CHU Morvan, 29609 Brest Cedex, France
    Arch Pediatr 12:1338-43. 2005
    ..To take in charge of an asthmatic child it is necessary to evaluate the lung function...
  28. ncbi Use of submaximal inhalation and spirometry to assess the effects of ozone exposure
    William F McDonnell
    Human Studies Division, National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Chapel Hill, North Carolina, USA
    Arch Environ Health 59:76-83. 2004
    ....
  29. ncbi Differences and relationships between residual volumes measured on land and in water calculated from estimate equations
    S Demura
    Faculty of Education, Kanazawa University, Kanazawa, Ishikawa, Japan
    J Sports Med Phys Fitness 47:309-15. 2007
    b>Residual volume error influences percent body fat estimated by hydrostatic...
  30. ncbi The structural basis of airways hyperresponsiveness in asthma
    Dan C Stănescu
    J Appl Physiol 101:1812; author reply 1813. 2006
  31. ncbi Dyspnoea at 6-min walk test in idiopathic pulmonary fibrosis: comparison with COPD
    Osamu Nishiyama
    Department of Respiratory Medicine and Allergy, Tosei General Hospital, 160 Nishioiwake cho, Seto, Aichi 489 8642, Japan
    Respir Med 101:833-8. 2007
    ..6+/-2.1 in IPF versus 4.6+/-1.9 in COPD, P<0.05). O(2) saturation is an independent predictor of dyspnoea at the end of a 6-min walk test in IPF. In comparison with COPD, desaturation is more severe, although dyspnoea is milder...
  32. ncbi Chest wall motion after thixotropy conditioning of inspiratory muscles in healthy humans
    Masahiko Izumizaki
    Department of Physiology, Showa University School of Medicine, 1 5 8 Hatanodai, Shinagawa ku, Tokyo, 142 8555 Japan
    J Physiol Sci 56:433-40. 2006
    ..05), being most obvious at 0.5 min (Delta 0.24 +/- 0.20 liter). After conditioning at residual volume, reductions in end-expiratory chest wall volume were significant at any time point (P < 0...
  33. ncbi The impact of positive end-expiratory pressure on functional residual capacity and ventilation homogeneity impairment in anesthetized children exposed to high levels of inspired oxygen
    Britta S von Ungern-Sternberg
    Division of Anesthesia, University Children s Hospital, Basel, Switzerland
    Anesth Analg 104:1364-8, table of contents. 2007
    ..We hypothesized that the use of a Fio2 of 1.0 results in a decrease of FRC and ventilation homogeneity compared with that of a Fio2 of 0.3, and that this decrease is prevented by PEEP of 6-cm H2O compared to a PEEP of 3-cm H2O...
  34. ncbi Bronchial measurement with three-dimensional quantitative thin-section CT in patients with cystic fibrosis
    Michel Montaudon
    Laboratory of Cellular Respiratory Physiology, Universite Bordeaux 2, Bordeaux, France
    Radiology 242:573-81. 2007
    ....
  35. ncbi [A twenty-year research on the pathogenesis of functional disorders of the respiratory tract in children and adolescents with idiopathic scoliosis]
    Ryszard Zaba
    Katedry i Oddzialu Klinicznego Pediatrii w Bytomiu, Slaskiej Akademii Medycznej w Katowicach
    Wiad Lek 55:998-1002. 2002
    ..The following indexes were defined: residual volume-RV, Intrathoracic gas volume-ITGV and total lung capacity-TLC...
  36. ncbi Comparison between total lung capacity and residual volume values obtained by pletysmography and single breath methods with methane
    Ricardo Marques Dias
    Gaffrée e Guinle University Hospital, and Laboratório de Função Pulmonar, Prócardiaco Hospital, Rua Dona Mariana 219, CEP 22280 020 Botafogo, Rio de Janeiro, RJ, Brazil
    Rev Port Pneumol 12:659-67. 2006
    ..Total lung capacity and residual volume were called TLC(PL) and RV(PL) when measured by pletysmography and TLC(SB) and RV(SB) when determined by ..
  37. pmc Inspiratory efforts during mechanical ventilation: is there risk of barotrauma?
    Stephen H Loring
    Chest 131:646-8. 2007
  38. ncbi Restrictive impairment in patients with asthma
    Albert Miller
    Pulmonary Division, Department of Medicine, St Vincent Catholic Medical Centers Queens Division, Mary Immaculate Hospital, Jamaica, NY 11432, USA
    Respir Med 101:272-6. 2007
    ..patients, the VC may be reduced by air trapping, with an increase in functional residual capacity (FRC) and residual volume (RV) (pseudorestriction). We have reported 12 asthmatic patients with reduced VC and no increase in RV, i.e...
  39. ncbi Respiratory function at age 8-9 years in extremely low birthweight/very preterm children born in Victoria in 1991-1992
    Lex W Doyle
    Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Victoria, Australia
    Pediatr Pulmonol 41:570-6. 2006
    ..In conclusion, the abnormalities in respiratory function in ELBW/very preterm children compared with NBW subjects described in the presurfactant era persisted in the 1990s, especially in those who had BPD in the newborn period...
  40. ncbi Airflow limitation and airway dimensions in chronic obstructive pulmonary disease
    Masaru Hasegawa
    First Department of Medicine, Hokkaido University School of Medicine, N 15 W 7 Kita ku, Sapporo 060 8638, Japan
    Am J Respir Crit Care Med 173:1309-15. 2006
    ..Computed tomography has been widely used to assess emphysema severity, but less attention has been paid to the assessment of airway disease using computed tomography...
  41. ncbi Two-year improvement in multidimensional body mass index, airflow obstruction, dyspnea, and exercise capacity index after nonresectional lung volume reduction surgery in awake patients
    Eugenio Pompeo
    Thoracic Surgery Division, Emphysema Center, Tor Vergata University, Rome, Italy
    Ann Thorac Surg 84:1862-9; discussion 1862-9. 2007
    ....
  42. ncbi Exaled nitric oxide and air trapping correlation in asthmatic children
    L Mappa
    Department of Pediatrics, University of Bari, Bari, Italy
    Allergy 60:1436-9. 2005
    ..aim of our study was to evaluate the correlation between eNo levels and functional residual capacity (FRC), residual volume (RV), RV to total lung capacity (TLC) ratio, and pulmonary resistances in asthmatic children ages 6-13 years...
  43. ncbi Effect of oral aminophylline on pulmonary function improvement and tolerability in different age groups of COPD patients
    Cheng Yu Chen
    Institute of Emergency and Critical Medicine, National Yang Ming University, Taipei, Taiwan, ROC
    Chest 128:2088-92. 2005
    ..This study attempted to explore the symptoms, pulmonary function improvement, and adverse events related to aminophylline therapy in COPD patients of different age groups...
  44. ncbi Which pulmonary volume should be used in physiotherapy to obtain higher maximal inspiratory pressure in COPD patients?
    Patricia E M Marinho
    Department of Physiotherapy, Federal University of Pernambuco, Recife, Brazil
    Physiother Res Int 10:182-9. 2005
    ..The aim of the present study was to evaluate the maximal inspiratory pressure (MIP) from the residual volume (RV) and from the functional residual capacity (FRC), in patients with COPD, and to determine which pulmonary ..
  45. ncbi The structural basis of airways hyperresponsiveness in asthma
    Robert H Brown
    Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Appl Physiol (1985) 101:30-9. 2006
    ..BSMT caused an increase in residual volume (RV) that was threefold greater than the decrease in forced vital capacity (FVC) because of a simultaneous ..
  46. ncbi Effects of chest wall strapping on mechanical response to methacholine in humans
    Roberto Torchio
    Pneumologia Fisiopatologia Respiratoria, Azienda Ospedaliera S Croce e Carle, Ospedale A Carle, Via Carle, 12100 Confreria Cuneo, Italy
    J Appl Physiol 101:430-8. 2006
    ..CWSon/on day, MCh caused greater increases in pulmonary resistance, upstream resistance, dynamic elastance, residual volume, and greater decreases in maximal expiratory flow than on the CTRL day...
  47. ncbi Influence of lung volume, glossopharyngeal inhalation and P(ET) O2 and P(ET) CO2 on apnea performance in trained breath-hold divers
    Kristian Overgaard
    Department of Sport Science, University of Aarhus, Katrinebjergvej 89C, 8200, Aarhus N, Denmark
    Eur J Appl Physiol 97:158-64. 2006
    ..7+/-0.6 kPa, P=0.48). In conclusion, GI increases lung volume, relaxed airway pressure and apnea performance in well-trained breath-hold divers...
  48. pmc Plethysmography and impulse oscillometry assessment of tiotropium and ipratropium bromide; a randomized, double-blind, placebo-controlled, cross-over study in healthy subjects
    D Singh
    Medicines Evaluation Unit, North West Lung Research Centre, Manchester, UK
    Br J Clin Pharmacol 61:398-404. 2006
    ..These methods have not been compared for their ability to assess long- and short-acting anticholinergic agents. We therefore performed a double-blind, placebo-controlled, four-way cross-over study in 30 healthy subjects...
  49. pmc Predictors of mortality in patients with emphysema and severe airflow obstruction
    Fernando J Martinez
    Division of Pulmonary and Critical Care Medicine, University of Michigan Health System, Ann Arbor, MI 48109 0360, and Section of Thoracic Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Am J Respir Crit Care Med 173:1326-34. 2006
    ..Limited data exist describing risk factors for mortality in patients having predominantly emphysema...
  50. ncbi Tiotropium and simplified detection of dynamic hyperinflation
    Arthur F Gelb
    Department of Pharmacy Services, Lakewood Regional Medical Center, Lakewood, CA 90712, USA
    Chest 131:690-5. 2007
    ..To detect dynamic hyperinflation (DH) by evaluating reduction in inspiratory capacity (IC) during metronome-paced hyperventilation (MPH) in patients with moderate-to-severe COPD, studied before and after treatment with tiotropium...
  51. pmc Predictors of progression of HRCT diagnosed fibrosing alveolitis in patients with rheumatoid arthritis
    J K Dawson
    Department of Rheumatology, St Helens and Knowsley Trust Hospitals, Liverpool, UK
    Ann Rheum Dis 61:517-21. 2002
    ..Fibrosing alveolitis (FA) is the most serious pleuropulmonary extra-articular feature of rheumatoid arthritis (RA). Features that predict progression of FA in patients with RA have not yet been determined...
  52. ncbi Oropharyngeal deglutition in stable COPD
    Babak Mokhlesi
    Division of Pulmonary and Critical Care, Northwestern University Medical School and the Veterans Administration Chicago Healthcare System Lakeside Division, IL, USA
    Chest 121:361-9. 2002
    ..The aim of this study was to examine deglutition in stable patients with COPD and lung hyperinflation...
  53. ncbi Association of lung perfusion disparity and mortality in patients with cystic fibrosis awaiting lung transplantation
    Michael L Stanchina
    Lung Transplant Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Heart Lung Transplant 21:217-25. 2002
    ..These patterns were compared with other pulmonary physiologic markers of ventilation and perfusion obtained from pulmonary function and cardiopulmonary exercise tests...
  54. ncbi Respiratory muscle strength, lung function, and dyspnea in patients with sarcoidosis
    A Baydur
    School of Medicine and Los Angeles County and University of Southern California Medical Center, University of Southern California, Los Angeles, CA, USA
    Chest 120:102-8. 2001
    ..RESULTS: Mean FVC, maximal voluntary ventilation, total lung capacity (TLC), functional residual capacity, residual volume (RV), and diffusing capacity of the lung for carbon monoxide (DLCO) were all at least 16% less than ..
  55. ncbi Effect of gravity on chest wall mechanics
    D Bettinelli
    Dipartimento di Medicina Sperimentale, Ambientale e Biotecnologie Mediche, Universita di Milano Bicocca, I 20052 Monza, Italy
    J Appl Physiol 92:709-16. 2002
    ..The data suggest that the chest wall does not behave as a linear system when exposed to changing gravity, as the effect depends on both chest wall volume and magnitude of G(z)...
  56. ncbi Inspiratory muscle training in a patient with left ventricular assist device
    Ioannis D Laoutaris
    Onassis Cardiac Surgery Center, Athens, Greece
    Hellenic J Cardiol 47:238-41. 2006
    ..Studies of different modes of rehabilitation in this population are lacking. We report the benefits of inspiratory muscle training on the exercise capacity and quality of life in the recipient of a left ventricular assist device...
  57. ncbi Centrilobular fibrosis: a novel histological pattern of idiopathic interstitial pneumonia
    Maria Eudóxia Pilotto de Carvalho
    Department of Pulmonary, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, SP, Brasil
    Pathol Res Pract 198:577-83. 2002
    ..All histological parameters were significantly different among the three groups (p < 0.001). CLF is a specific, homogeneous, and recognizable histological pattern of IIP, and can be isolated from UIP and NSIP...
  58. ncbi Long-term outcome of staged versus one-stage bilateral thoracoscopic reduction pneumoplasty
    Eugenio Pompeo
    Department of Thoracic Surgery, Tor Vergata University, Policlinico Tor Vergata, Via Oxford 81, 00133 Rome, Italy
    Eur J Cardiothorac Surg 21:627-33; discussion 633. 2002
    ....
  59. ncbi Can high resolution computed tomography predict lung function in patients with chronic obstructive pulmonary disease?
    K Spiropoulos
    Division of Pulmonology, Laboratory of Cardiopulmonary Exercise Test, Patras, Greece
    Lung 181:169-81. 2003
    ..027), forced expiratory volumein 1 sec (FEV1) (r = -0.632, p = 0.002), resistance (r = 0.674, p = 0.001), residual volume (RV) (r = 0.733, p = 0.001), total lung capacity (TLC) (r = 0.696, p = 0...
  60. ncbi Nephrogenic diabetes insipidus with dilatation of bilateral renal pelvis, ureter and bladder
    Xiao dong Jin
    Department of Urology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
    Scand J Urol Nephrol 43:73-5. 2009
    ..Nephrogenic diabetes insipidus (NDI) with dilatation of upper urinary tract and bladder is rarely reported. This study evaluated the urological manifestations and treatment results of this rare condition...
  61. ncbi Effect of 5-hydroxytryptamine1 serotonin receptor agonists on noxiously stimulated micturition in cats with chronic spinal cord injury
    Baojun Gu
    Department of Surgery, Veterans Affairs Medical Center, Duke University Medical Center, Durham, NC 27710, USA
    J Urol 177:2381-5. 2007
    ....
  62. ncbi Scrotal edema secondary to fluid imbalance in patients on continuous peritoneal dialysis
    Muniru Adeniyi
    Section of Nephrology, Raymond G Murphy VA Medical Center, Albuquerque, New Mexico 87108, USA
    Adv Perit Dial 25:68-71. 2009
    ..showed no dialysate leaks, and peritoneal equilibration test (PET) revealed high-average transport with a residual volume above, and an ultrafiltration volume below, the expected range...
  63. pmc Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis
    John J Bissler
    Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    N Engl J Med 358:140-51. 2008
    ..The drug sirolimus suppresses mTOR signaling...
  64. ncbi Does lobectomy for lung cancer in patients with chronic obstructive pulmonary disease affect lung function? A multicenter national study
    Sergio Baldi
    Pulmonary Division, University Hospital S Giovanni Battista of Torino, Torino, Italy
    J Thorac Cardiovasc Surg 130:1616-22. 2005
    ..The purpose of this study was to evaluate the effect of lobectomy on pulmonary function in patients with chronic obstructive pulmonary disease...
  65. ncbi Randomised, placebo controlled, double blind study of alfuzosin SR in patients undergoing trial without catheter following acute urinary retention
    T Shah
    Department of Urology, Bradford Hospitals NHS Trust, St Lukes Hospital, Little Horton Lane, Bradford BD5 0NA, West Yorkshire, UK
    Eur Urol 42:329-32; discussion 332. 2002
    ..There is no conclusive evidence of the efficacy of this treatment. We conducted a study to evaluate the efficacy of using the alpha-blocker alfuzosin SR in patients with acute urinary retention...
  66. ncbi Prospective randomized trial comparing bilateral lung volume reduction surgery to pulmonary rehabilitation in severe chronic obstructive pulmonary disease
    G J Criner
    Divisions of Pulmonary and Critical Care Medicine, Department of Medicine and Cardiothoracic Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    Am J Respir Crit Care Med 160:2018-27. 1999
    ..65 +/- 0.16 L, p < 0.005) increased whereas TLC (6.53 +/- 1.3 versus 7.65 +/- 2.1 L, p < 0.001) and residual volume (RV) (3.7 +/- 1.2 versus 4.9 +/- 1.1 L, p < 0...
  67. ncbi Respiratory evaluation of patients on continuous ambulatory peritoneal dialysis prior to renal transplantation
    G Ulubay
    Department of Pulmonary Diseases, Baskent University Faculty of Medicine, Ankara, Turkey
    Clin Nephrol 66:269-74. 2006
    ..The aim of this study was to investigate whether PFT and CPET results are altered in patients on continuous ambulatory peritoneal dialysis (CAPD) according to the presence of dialysis solution in the abdomen...
  68. pmc A comparison of peak expiratory flow measured from forced vital capacity and peak flow meter manoeuvres in healthy volunteers
    Dipti Agarwal
    Department of Physiology, Postgraduate Institute of Medical Sciences, Rohtak, India
    Ann Thorac Med 2:103-6. 2007
    ..chest wall and respiratory muscles by assessing the total volume of air exhaled from total lung capacity to residual volume. Spirometry and peak flow measurements have usually been carried out on separate equipments using different ..
  69. ncbi Comparison of cisapride and metoclopramide for facilitating gastric emptying and improving tolerance to intragastric enteral nutrition in critically III, mechanically ventilated adults
    R MacLaren
    School of Pharmacy, University of Colorado Health Sciences Center, Denver 80262, USA
    Clin Ther 23:1855-66. 2001
    ..Placebo-controlled studies have indicated that both cisapride and metoclopramide promote gastric motility in critically ill patients...
  70. pmc Lung volumes and respiratory mechanics in elastase-induced emphysema in mice
    Z Hantos
    Dept of Medical Informatics, Univ of Szeged, Koranyi fasor 9, H 6720 Szeged, Hungary
    J Appl Physiol (1985) 105:1864-72. 2008
    Absolute lung volumes such as functional residual capacity, residual volume (RV), and total lung capacity (TLC) are used to characterize emphysema in patients, whereas in animal models of emphysema, the mechanical parameters are ..
  71. ncbi Effect of elastic compression stockings on venous hemodynamics during walking
    Veronica Ibegbuna
    Irvine Laboratory, Academic Vascular Surgery, Imperial College, Faculty of Medicine, Division of Surgery, Anaesthetics and Intensive Care, St Mary s Hospital, Paddington, London, England
    J Vasc Surg 37:420-5. 2003
    ....
  72. ncbi Lung volume effects on pharyngeal swallowing physiology
    Roxann Diez Gross
    Department of Audiology and Speech Pathology, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA
    J Appl Physiol (1985) 95:2211-7. 2003
    ..consistency boluses at three randomized lung volumes: total lung capacity, functional residual capacity, and residual volume. The results showed that pharyngeal activity duration of deglutition for swallows produced at residual volume ..
  73. ncbi Spiral CT evaluation of pulmonary emphysema using a low-dose technique
    M Zompatori
    Radiologia Zompatori, Policlinico S Orsola Malpighi, Bologna, Italy
    Radiol Med 104:13-24. 2002
    ....
  74. ncbi Transurethral resection versus minimally invasive treatments of benign prostatic hyperplasia: results of treatments. Our experience
    Daniele Minardi
    Institute of Urology, Polytechnic University of the Marche Region, Medical School, Ancona, Italy
    Arch Ital Urol Androl 76:11-8. 2004
    ..In this non-randomized prospective study the results of standard TURP (Transurethral Resection of the Prostate) versus other minimally invasive treatments were compared...
  75. ncbi Autonomic nervous system overactivity in men with lower urinary tract symptoms secondary to benign prostatic hyperplasia
    Kevin T McVary
    Department of Urology, Feinberg School of Medicine, Northwestern University Chicago, Illinois 60611, USA
    J Urol 174:1327-433. 2005
    ..We investigated the relationship of ANS activity to LUTS as well as to objective measures of BPH in men with BPH...
  76. ncbi Gallbladder motility and cholesterol crystallization in bile from patients with pigment and cholesterol gallstones
    P Portincasa
    University Medical School, Bari, Italy Hospital of Bisceglie, Italy University Hospital Utrecht, The Netherlands
    Eur J Clin Invest 30:317-24. 2000
    ..Little is known about gallbladder motility in patients with black pigment stones when compared to cholesterol gallstone patients, or about their relationship to biliary composition, crystallization and stone characteristics...
  77. pmc Lung volume does not alter the distribution of pulmonary perfusion in dependent lung in supine humans
    Susan R Hopkins
    Department of Medicine, Division of Physiology, University of California, San Diego, La Jolla, CA 92093 0623, USA
    J Physiol 588:4759-68. 2010
    ..capacity (TLC), affects the dependent 11 cm at functional residual capacity (FRC) and almost all the lung at residual volume (RV)...
  78. ncbi Alterations in the pulmonary function tests of inflammatory bowel diseases
    Fehmi Ates
    Department of Gastroenterology, Mersin University School of Medicine, Mersin, Turkey
    Turk J Gastroenterol 22:293-9. 2011
    ..We aimed to determine the changes in the pulmonary function tests of the patients with inflammatory bowel diseases...
  79. ncbi Plethysmographic lung volumes in children with sighing dyspnea
    Kin Sun Wong
    Department of Pediatrics, Division of Pediatric Pulmonology, Chang Gung Children s Hospital, Chang Gung University, College of Medicine, 5, Fu Hsin Street, Taoyuan, Taiwan
    Pediatr Int 51:405-8. 2009
    ..This study compared the plethysmographic lung volumes of children with sighing dyspnea with healthy children and tested the hypothesis that sighing children suffer from hyperinflation or gas trapping as a cause of dyspnea...
  80. ncbi Pulmonary function tests as a predictor of quantitative and qualitative outcomes after thoracic surgery for lung cancer
    Laurent Greillier
    Department of Thoracic Oncology, Université de la Méditerranée Assistance Publique, Hopitaux de Marseille, France
    Clin Lung Cancer 8:554-61. 2007
    ..We studied the impact of pulmonary function tests on both quantitative (morbidity, mortality, and overall survival [OS]) and qualitative (quality of life [QOL]) outcomes of patients undergoing thoracic surgery for NSCLC...
  81. ncbi Clinical and hemodynamic significance of the greater saphenous vein diameter in chronic venous insufficiency
    Tulio P Navarro
    Vascular Laboratory, Federal University Hospital, Minas Gerais, Belo Horizonte, Brazil
    Arch Surg 137:1233-7. 2002
    ....
  82. ncbi Long-term effect of the beta2-receptor agonist procaterol on daily life performance and exercise capacity in patients with stable chronic obstructive pulmonary disease. Clinical study with special reference to health-related quality of life and activities
    Takanobu Shioya
    Department of Physical Therapy, Akita University School of Health Sciences, Akita, Japan
    Arzneimittelforschung 58:24-8. 2008
    ..1 second (FEV1), forced vital capacity (FVC), total lung capacity (TLC), functional residual capacity (FRC), residual volume (RV), maximal inspiratory pressure (PImax), and maximal expiratory pressure (PEmax) were significantly ..
  83. pmc Gallbladder emptying in patients with primary sclerosing cholangitis
    Karouk Said
    Department of Gastroenterology and Hepatology, Karolinska Institute, Karolinska University Hospital, Huddinge, 14186 Stockholm, Sweden
    World J Gastroenterol 15:3498-503. 2009
    ..To assess gallbladder emptying and its association with cholecystitis and abdominal pain in patients with primary sclerosing cholangitis (PSC)...
  84. pmc Origin of exhaled breath particles from healthy and human rhinovirus-infected subjects
    Patricia Fabian
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02215, USA
    J Aerosol Med Pulm Drug Deliv 24:137-47. 2011
    ..Exhaled breath studies suggest that humans exhale fine particles during tidal breathing, but little is known of their physical origin in the respiratory system during health or disease...
  85. ncbi Body plethysmography--its principles and clinical use
    C P Criee
    Evangelisches Krankenhaus Göttingen Weende gGmbH, Department of Pneumology, Respiratory Care, Sleep Medicine, Pappelweg 5, D 37120 Bovenden Lenglern, Germany
    Respir Med 105:959-71. 2011
    ..In combination with deep expirations and inspirations, total lung capacity (TLC) and residual volume (RV) can be determined. Airway resistance (Raw) is calculated as the ratio of sRaw to FRC(pleth)...
  86. pmc Pulmonary dysfunction in survivors of childhood hematologic malignancies after allogeneic hematopoietic stem cell transplantation
    Hiroto Inaba
    Department of Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Cancer 116:2020-30. 2010
    ..The number of long-term survivors of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is increasing; however, few studies have addressed their long-term pulmonary function...
  87. ncbi Comparison of helium dilution and plethysmographic lung volumes in pregnant women
    F Garcia-Rio
    Servicio de Neumologia, Hospital Universitario La Paz, Madrid, Spain
    Eur Respir J 10:2371-5. 1997
    ..Total lung capacity (TLC), functional residual capacity (FRC) and residual volume (RV) were measured by multibreath helium equilibration (TLCHe, FRCHe and RVHe) and by plethysmography (TLCbox,..
  88. ncbi Rat model of lung fibrosis: comparison of functional, biochemical, and histopathological changes 4 months after single irradiation of the right hemithorax
    J Pauluhn
    Institute of Toxicology, Bayer AG, Building No 514, 42096, Wuppertal, Germany
    Toxicology 161:153-63. 2001
    ..Total lung capacity (TLC) was significantly decreased, while the residual volume (RV) and functional residual capacity (FRC) remained almost unchanged...
  89. ncbi Tidal airway closure during bronchoconstriction in asthma: usefulness of lung volume measurements
    Claudio Tantucci
    Unit of Respiratory Medicine, Department of Medical and Surgical Sciences, University of Brescia, 1st Medicina, Spedali Civili, Brescia, Italy
    J Asthma 48:33-40. 2011
    ..The presence and extent of tidal airway closure is not routinely assessed in asthma. The objective of this study was to provide a simple functional tool able to detect tidal airway closure during bronchoconstriction in asthma...
  90. ncbi Volume displaced by diaphragm motion in emphysema
    B Singh
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, University of Western Australia, Nedlands, Western Australia 6009, Australia
    J Appl Physiol (1985) 91:1913-23. 2001
    ..displaced by diaphragm motion (DeltaVdi), we compared nine subjects with emphysema and severe hyperinflation [residual volume (RV)/total lung capacity (TLC) 0.65 +/- 0.08; mean +/- SD] with 10 healthy controls...
  91. pmc Determinants of lung volumes in chronic spinal cord injury
    Evan L Stepp
    Research and Development Service, Department of Veterans Affairs, VA Boston Healthcare System, West Roxbury, MA 02132, USA
    Arch Phys Med Rehabil 89:1499-506. 2008
    ..To characterize determinants of lung volumes in chronic spinal cord injury (SCI)...
  92. ncbi [Study of erythromycin and metoclopramide in treatment of feeding intolerance of critically ill patients in intensive care unit]
    Nian Fang Lu
    Intensive Care Unit, Subei People s Hospital of Jiangsu Province, Clinical Medical School of Yangzhou University, Yangzhou 225001, Jiangsu, China
    Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 22:36-9. 2010
    ..To compare the effect of erythromycin and metoclopramide on feeding intolerance of critically ill patients in intensive care unit (ICU)...
  93. ncbi Tiotropium administered by a pressurized metered dose inhaler (pMDI) and spacer produces a similar bronchodilator response as that administered by a Rotahaler in adult subjects with stable moderate-to-severe COPD
    B Brashier
    Chest Research Foundation, Marigold Complex, Kalyaninagar, Pune 411014, India
    Respir Med 101:2464-71. 2007
    ..The clinical efficacy of this mode of tiotropium delivery has, so far, not been compared with the currently available dry powder inhaler (DPI) devices...
  94. ncbi [Ultrasound guided transthoracic biopsy - safety and efficaces]
    H J Seyfarth
    Abteilung Pneumologie der Universität Leipzig
    Pneumologie 61:563-7. 2007
    ..The biopsy techniques differ with respect to the guiding imaging method, the devices used and the quantity of specimen. This study investigates efficacy and safety of the ultrasound guided transthoracic biopsy...
  95. ncbi A syringe simulation of biological controls for quality assessment of prospective lung volume measurements
    Maarten K Ninaber
    Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands
    Respiration 76:187-92. 2008
    ....
  96. ncbi Effects of antimuscarinics on voiding function after cerebral infarction in a rat model of overactive bladder
    Anwar Yusup
    Department of Urology, Faculty of Medical Science, University of Fukui, 23 3 Shimoaizuki, Matsuoka, Fukui 910 1193, Japan
    Eur J Pharmacol 577:143-9. 2007
    ..Low-dose i.v. tolterodine (<or=20 nmol/kg) significantly reversed this effect without altering residual volume or bladder contraction pressure. Low-dose i.v...
  97. ncbi Study of eye drops dispensing and dose variability by using plastic dropper tips
    Zdenka Sklubalova
    Department of Pharmaceutical Technology, Charles University in Prague, Faculty of Pharmacy, Hradec Kralove, Czech Republic
    Drug Dev Ind Pharm 32:197-205. 2006
    ..02%, the dispensing angle from 90 degrees to 30 degrees from horizontal, and the residual volume of liquid in the dropper bottle from 4 to 10 mL on the mean drop weights were examined...
  98. ncbi Hemodynamic impairment, venous segmental disease, and clinical severity scoring in limbs with Klippel-Trenaunay syndrome
    Konstantinos T Delis
    Division of Vascular Surgery, Mayo Clinic, Rochester, MN 55905, USA
    J Vasc Surg 45:561-7. 2007
    ..With the purpose of determining the actual significance of venous impairment in patients with KTS, we quantified the venous valvular competency and calf muscle pump function and examined their effect on clinical severity...
  99. ncbi Immediate Foley removal after laparoscopic and vaginal hysterectomy: determinants of postoperative urinary retention
    Fabio Ghezzi
    Department of Obstetrics and Gynecology, University of Insubria, Del Ponte Hospital, Varese, Italy
    J Minim Invasive Gynecol 14:706-11. 2007
    ....
  100. ncbi Prokinetic therapy for feed intolerance in critical illness: one drug or two?
    Nam Q Nguyen
    Department of Gastroenterology and Hepatology, University of Adelaide, Royal Adelaide Hospital, South Australia
    Crit Care Med 35:2561-7. 2007
    ..To compare the efficacy of combination therapy, with erythromycin and metoclopramide, to erythromycin alone in the treatment of feed intolerance in critically ill patients...
  101. ncbi Outcome of bilateral lung volume reduction in patients with emphysema potentially eligible for lung transplantation
    B F Meyers
    Division of Cardiothoracic Surgery and the Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, MO, USA
    J Thorac Cardiovasc Surg 122:10-7. 2001
    ..The outcomes of these 99 patients are reviewed to assess the consequences of proceeding with lung volume reduction surgery on patients potentially eligible for lung transplantation...

Research Grants38

  1. Forced expiration and lung volume in infant lung disease
    MOHY MORRIS; Fiscal Year: 2006
    ..The P.I. will use his novel noninvasive technique for measuring the residual volume (RV) by the nitrogen washout technique...
  2. Bladder and Sphincter Control after Spinal Cord Injury
    Changfeng Tai; Fiscal Year: 2012
    ..With this approach, a large bladder capacity and low pressure voiding with a minimal residual volume of urine will be expected...
  3. Alternative Therapies for BPH, Multiethnic Variability
    Steven A Kaplan; Fiscal Year: 2010
    ..Post-void residual volume, PSA level...
  4. PHASE III TRIAL FO SIROLIMUS IN LYMPHANGIOLEIOMYLMATOSIS
    Francis McCormack; Fiscal Year: 2009
    ..Secondary outcome measures will include forced vital capacity, residual volume, diffusing capacity, six minute walk, cyst volume percent based on volumetric CT, all-cause mortality and ..
  5. NURSING MODEL--RESPIRATORY MUSCLE STRENGTH IN COPD
    Janet Larson; Fiscal Year: 2001
    ..muscle strength measured as the maximal inspiratory pressure, (2) hyperinflation defined as the ratio of the residual volume to total lung capacity, (3) body composition measured with dual energy x-ray absorptiometry, skinfold ..
  6. DELIRIUM AMONG THE ELDERLY IN RURAL LTC FACILITIES
    Kennith Culp; Fiscal Year: 2003
    ..with a portable photometric urine analyzer and an ultrasound of the urinary bladder for post-void residual volume using a BladderScan BVT3000...
  7. MECHANISMS FOR ALTERED DETRUSOR CONTRACTILITY IN DIABET
    Samuel Chacko; Fiscal Year: 2002
    ..with a spectrum of voiding dysfunctions characterized by impaired bladder sensation, increased postvoidal residual volume and decreased detrusor contractility that may progress in detrusor areflexia and diminished urinary flow...
  8. Modeling of Aerosol Transport in Alveolated Airways
    Chantal Darquenne; Fiscal Year: 2009
    ..The results of this study will provide a link to the mechanisms by which even seemingly modest PM exposure can cause or exacerbate lung disease and will also help to better design spatial targeting of inhaled drugs. ..
  9. Pneumografting - a novel cell-based therapy for emphysema
    Edward P Ingenito; Fiscal Year: 2010
    ..We intend to advance this approach, known as pneumografting, into human trials under a physician-sponsored Investigation New Drug Application. ..
  10. Force Propagation of Emphysema in Vivo
    Edward Ingenito; Fiscal Year: 2007
    ..The results of these experiments will provide new insight into the role of mechanical forces in promoting injury in the intact emphysema lung, and the effect of mechanical forces on tissue remodeling. [unreadable] [unreadable]..
  11. Responses to Surgical and Bronchoscopic Volume Reduction
    Edward Ingenito; Fiscal Year: 2006
    ..We believe that by accomplishing these objectives, we can help advance this technology into the clinical arena. ..
  12. Urodynamic and Multiethnic Variability of Men Treated b*
    Steven Kaplan; Fiscal Year: 2005
    ..Baseline urodynamic parameters which may predict improved outcome after MIST 3. The success of various types of MIST in treating BPH in African - American, Hispanic and Caucasian men. ..
  13. Deposition of 0.5 to 2 Micron Aerosol in the Human Lung
    G Prisk; Fiscal Year: 2003
    ..5 to 1 micron). Such information will provide a much-improved basis for the assessment of exposure to small inhaled particles both in long duration spaceflight and on Earth. ..
  14. The Effect of Pulmonary Interstitial Edema on Gas Exchange
    G Prisk; Fiscal Year: 2009
    ..3) Define and quantify the relationship between alterations in the heterogeneity of pulmonary blood flow and lung water content using functional magnetic resonance imaging (fMRI) and X-ray techniques. ..
  15. Integrity of the Pulmonary Blood-Gas Barrier
    John West; Fiscal Year: 2007
    ..In addition, at the more basic level, this research is devoted to a fundamental biological dilemma of the lung, namely how the blood-gas barrier combines extreme thinness with immense strength. [unreadable] [unreadable]..
  16. DETECTING ASPIRATION ASSOCIATED WITH TUBE FEEDINGS
    Norma Metheny; Fiscal Year: 2007
    ..Modifiable risk factors for aspiration include feeding site, tube position, patient position, and gastric residual volume (GRV)...
  17. Development of a 'Nurse-Friendly' Bedside Test for Aspiration
    Norma A Metheny; Fiscal Year: 2010
    ....
  18. Lung Perfusion Heterogeneity and Mechanisms of Edema
    Susan R Hopkins; Fiscal Year: 2010
    ..abstract_text> ..
  19. Telomere Length as a Marker of Cardiovascular Aging
    Ellen Demerath; Fiscal Year: 2005
    ..Telomeric DNA length may thus be found to be a valuable plasma biomarker for the prediction and monitoring of cardiovascular health and aging. ..
  20. Natural History of Prostatism: The Olmsted County Study
    JENNIFER LYNN ST SAUVER; Fiscal Year: 2010
    ....
  21. Ventilator-induced diaphragm dysfunction
    SANFORD NO MIDDLE NAME LEVINE; Fiscal Year: 2010
    ..Moreover, these studies may directly lead to therapy for this newly recognized but relatively common disease of diaphragm muscle. ..
  22. Utility of Rapamycin for the Treatment of Renal Angiomy*
    John Bissler; Fiscal Year: 2004
    ..Successful completion of the aim of this study will help to establish tuberous sclerosis as a valuable model for targeted molecular therapy for neoplasia. ..
  23. Platelet-Derived Growth Factor, Remodeling and Asthma
    Monica Kraft; Fiscal Year: 2010
    ..This proposal will also determine whether PDGF inhibition could provide important adjuvant therapy for the treatment of severe asthmatics by limiting structural changes that result from activity of this pathway. ..
  24. STRUCTURAL MECHANISMS OPERATING IN UNRESPONSIVE ASTHMA
    Robert Brown; Fiscal Year: 2003
    ....
  25. REGULATION OF PROSTATE GROWTH BY NEURAL FACTORS
    Kevin McVary; Fiscal Year: 2001
    ..Using this model allows one to explore the limits of understanding prostatic neuroregulation, to explore neurotrophic influences on exocrine gland development, and to possibly uncover novel methods to influence prostate disease. ..
  26. The Efficacy of TUMT and Neoadjuvant Finasteride for BPH
    Kevin McVary; Fiscal Year: 2005
    ..We are proposing a 3-arm, placebo/sham controlled, randomized clinical trial using changes in symptoms as the primary ..
  27. GROWTH OF AIRWAYS AND LUNG PARENCHYMA IN NORMAL INFANTS
    Robert Tepper; Fiscal Year: 2009
    ..abstract_text> ..
  28. Airway as Target Organ in Infants with Atopic Dermatitis
    Robert Tepper; Fiscal Year: 2008
    ..Specific Aim # 2: Evaluate whether the presence of phenotypic characteristics of the asthmatic airway identifies infants and toddlers that develop clinical asthma by 5 years of age. [unreadable] [unreadable]..
  29. Genetic epidemiology of TLR4 alleles and bacteremia
    Jason Chien; Fiscal Year: 2006
    ..Ultimately, this cohort of patients will be developed in anticipation of future genetic discoveries in the complicated pathway of pathogen recognition and host inflammatory response. ..
  30. Respiratory Function in Infants with Persistent Wheezing
    AMY GOLDSTEIN FILBRUN; Fiscal Year: 2006
    ..Bronchodilator response will be assessed by changes in maximal flow following bronchodilator. Parents will also complete a symptom diary and respiratory history questionnaire. ..
  31. Air Disinfection Interventions in Grade Schools
    MARIA FABIAN; Fiscal Year: 2006
    ..Data will be modeled using advanced logistic regression models to determine effectiveness of interventions. ..
  32. Randomized Trial for Botox for Urinary Incontinence
    Michael Flynn; Fiscal Year: 2006
    ..It will provide valuable data to allow for further studies on the clinical and cost-effectiveness of Botox for detrusor instability and urge urinary incontinence. ..
  33. Extra-Fine Inhaled Corticosteroid Effect on Distal Lung Disease in Asthma
    Michelle Zeidler; Fiscal Year: 2007
    ..Non-invasive markers of distal disease include: 1) quantitative analysis of thoracic computed tomography at residual volume (RV) before and after methacholine challenge; 2) physiologic measures of small airways disease including RV, ..
  34. Clinical Center-COPD Clinical Research Network
    Jeffrey Hasday; Fiscal Year: 2007
    ..In addition to presenting these formal proposals, we have developed several concept proposals. We have also offered the development of a health cost utilization core for the COPD CRN. ..
  35. Strategies to Prevent COPD Exacerbation
    Fernando Martinez; Fiscal Year: 2007
    ..abstract_text> ..
  36. DNA Replication Fork: Pausing, Recombination and Disease
    John Bissler; Fiscal Year: 2007
    ..By understanding the effects of these sequences on the fidelity of DNA replication, therapeutic inroads into delaying disease onset can be made. ..
  37. N O S AND NEUROPATHIC AND ENDOTHELIAL INDUCED ED
    Kevin McVary; Fiscal Year: 2002
    ..Results of this research will aid in the understanding of how diabetic neuropathy contributes to sexual dysfunction and elucidate possible mechanisms to prevent them. ..
  38. Minimally Invasive Surgical Therapies Treatment Consort*
    Claus Roehrborn; Fiscal Year: 2005
    ..The MIST Study Group will be a blueprint for a technology assessment group applicable to other areas of urology and other medical or surgical subspecialties. ..