Genomes and Genes
respiratory function tests
Summary: Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.
Publications291 found, 100 shown here
- Interpretative strategies for lung function testsR Pellegrino
Internal Medicine, University of Genoa, V le Benedetto XV, 6, Genova I 16132, Italy
Eur Respir J 26:948-68. 2005
- Standardisation of the single-breath determination of carbon monoxide uptake in the lungN MacIntyre
Duke University Medical Center, Durham, NC, USA
Eur Respir J 26:720-35. 2005
- General considerations for lung function testingM R Miller
University Hospital Birmingham NHS Trust, UK
Eur Respir J 26:153-61. 2005
- Characteristics of physical activities in daily life in chronic obstructive pulmonary diseaseFabio Pitta
Respiratory Rehabilitation and Respiratory Division, University Hospital Gasthuisberg, Herestraat 49, B 3000 Leuven, Belgium
Am J Respir Crit Care Med 171:972-7. 2005..28 < r < 0.64, p < 0.05). Patients with chronic obstructive pulmonary disease are markedly inactive in daily life. Functional exercise capacity is the strongest correlate of physical activities in daily life...
- Genome-wide association study identifies five loci associated with lung functionEmmanouela Repapi
Departments of Health Sciences and Genetics, Adrian Building, University of Leicester, Leicester, UK
Nat Genet 42:36-44. 2010..These associations offer mechanistic insight into pulmonary function regulation and indicate potential targets for interventions to alleviate respiratory disease...
- The relationship between reduced lung function and cardiovascular mortality: a population-based study and a systematic review of the literatureDon D Sin
Department of Medicine, Respiratory Division, University of British Columbia, and The James Hogg iCAPTURE Center for Cardiovascular and Pulmonary Research, St Paul s Hospital, Room 368A, 1081 Burrard St, Vancouver, BC V6Z 1Y6, Canada
Chest 127:1952-9. 2005..We sought to determine the relationship between reduced FEV1 and cardiovascular mortality, independent of smoking...
- New reference values for forced spirometry in white adults in BrazilCarlos Alberto de Castro Pereira
Service of Pulmonology Department, Hospital do Servidor Publico Estadual, HSPE, Sao Paulo, SP, Brazil
J Bras Pneumol 33:397-406. 2007..To describe spirometric reference equations for healthy Brazilian adults who have never smoked and to compare the predicted values with those derived in 1992...
- Outcomes for COPD pharmacological trials: from lung function to biomarkersM Cazzola
Unit of Respiratory Diseases, Dept of Internal Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
Eur Respir J 31:416-69. 2008..Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations...
- Relationship between serum 25-hydroxyvitamin d and pulmonary function in the third national health and nutrition examination surveyPeter N Black
Department of Medicine, University of Auckland, Private Bag 92019 Auckland, New Zealand
Chest 128:3792-8. 2005..Low concentrations of vitamin D have been associated with a number of diseases, including osteoporosis, hypertension, and type I diabetes. It is possible that serum concentrations of vitamin D might also influence pulmonary function...
- Efficacy of salmeterol/fluticasone propionate by GOLD stage of chronic obstructive pulmonary disease: analysis from the randomised, placebo-controlled TORCH studyChristine R Jenkins
Woolcock Institute of Medical Research, Sydney, Australia
Respir Res 10:59. 2009..However, there are only limited data about the influence of GOLD severity staging on the effectiveness of SFC, particularly in patients with milder disease...
- A longitudinal, population-based, cohort study of childhood asthma followed to adulthoodMalcolm R Sears
Firestone Institute for Respiratory Health, Department of Medicine, McMaster University and St Joseph s Healthcare, Hamilton, Ont, Canada
N Engl J Med 349:1414-22. 2003..The outcome of childhood asthma in adults has been described in high-risk cohorts, but few population-based studies have reported the risk factors for persistence and relapse...
- Body composition and mortality in chronic obstructive pulmonary diseaseAnnemie M W J Schols
Department of Respiratory Medicine, University of Maastricht, Maastricht, Netherlands
Am J Clin Nutr 82:53-9. 2005..Survival studies have consistently shown significantly greater mortality rates in underweight and normal-weight patients with chronic obstructive pulmonary disease (COPD) than in overweight and obese COPD patients...
- Identification of chronic obstructive pulmonary disease in lung cancer screening computed tomographic scansOnno M Mets
Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, Postbus 85500, 3508GA Utrecht, The Netherlands
JAMA 306:1775-81. 2011..Smoking is a major risk factor for both cancer and chronic obstructive pulmonary disease (COPD). Computed tomography (CT)-based lung cancer screening may provide an opportunity to detect additional individuals with COPD at an early stage...
- Interpreting thresholds for a clinically significant change in health status in asthma and COPDP W Jones
St George s Hospital Medical School, London, UK
Eur Respir J 19:398-404. 2002..Finally, an attempt is made to translate these thresholds into scenarios that illustrate what a clinically significant change with treatment may mean to an individual patient...
- Hospitalizations and mortality in the Lung Health StudyNicholas R Anthonisen
University of Manitoba, Winnipeg, Manitoba, Canada
Am J Respir Crit Care Med 166:333-9. 2002..When all participants were considered and smoking status considered as a time-dependent covariate, smoking cessation was associated with significant reductions in fatal or nonfatal cardiovascular disease and coronary artery disease...
- A genome-wide association study of pulmonary function measures in the Framingham Heart StudyJemma B Wilk
Department of Neurology, Boston University School of Medicine, Boston, MA, USA
PLoS Genet 5:e1000429. 2009..Though it is unclear what gene or regulatory effect explains the association, the region warrants further investigation...
- CT scan findings of emphysema predict mortality in COPDAkane Haruna
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Sakyo ku, Kyoto, Japan
Chest 138:635-40. 2010..However, few studies have assessed the relationship between CT scan assessment and COPD mortality from mild to severe stages of the disease. In this study, we analyzed this relationship in patients with various stages of COPD...
- Health-related quality of life is related to COPD disease severityElisabeth Stahl
Department of Respiratory Medicine and Allergology, University Hospital, SE 221 85 Lund, Sweden
Health Qual Life Outcomes 3:56. 2005..The aim of this study was to evaluate the association between health-related quality of life (HRQL) and disease severity using lung function measures...
- The effects of body mass index on lung volumesRichard L Jones
Pulmonary Division, University of Alberta, Edmonton, AB, Canada T6G 2B7
Chest 130:827-33. 2006..It is well known that obesity causes decreases in lung volumes, but there has never been a large study showing the correlation between body mass index (BMI) and the various lung volumes...
- Pulmonary function is a long-term predictor of mortality in the general population: 29-year follow-up of the Buffalo Health StudyH J Schünemann
Department of Social and Preventive Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, NY 14214 3000, USA
Chest 118:656-64. 2000..The purpose of this study was to investigate the predictive value of pulmonary function by gender after 29 years of follow-up...
- Annual change in pulmonary function and clinical phenotype in chronic obstructive pulmonary diseaseMasaharu Nishimura
First Department of Medicine, Hokkaido University School of Medicine, and Center for Respiratory Diseases, Hokkaido Social Insurance Hospital, N 15 W 7, Kita ku, Sapporo 060 8638, Japan
Am J Respir Crit Care Med 185:44-52. 2012..Although the rate of annual decline in FEV1 is one of the most important outcome measures in chronic obstructive pulmonary disease (COPD), little is known about intersubject variability based on clinical phenotypes...
- Gender and COPD in patients attending a pulmonary clinicJuan P de Torres
Respiratory Research Unit, Hospital Nuestra Sra de Candelaria, Tenerife, Spain
Chest 128:2012-6. 2005..To compare gender differences in the clinical expression of COPD patients attending a pulmonary clinic...
- Effect of salmeterol on the ventilatory response to exercise in chronic obstructive pulmonary diseaseD E O'Donnell
Respiratory Investigation Unit, Dept of Medicine, Queen s University, Kingston, Canada
Eur Respir J 24:86-94. 2004..Bronchodilator-induced lung deflation reduced mechanical restriction, increased ventilatory capacity and decreased respiratory discomfort, thereby increasing exercise endurance...
- Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosisJohn J Bissler
Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
N Engl J Med 358:140-51. 2008..The drug sirolimus suppresses mTOR signaling...
- Midthigh muscle cross-sectional area is a better predictor of mortality than body mass index in patients with chronic obstructive pulmonary diseaseKarine Marquis
Centre de Recherche, Hopital Laval, Institut Universtaire de Cardiologie et de Pneumologie de L Université Laval, Quebec, Canada
Am J Respir Crit Care Med 166:809-13. 2002..These findings suggest that the assessment of body composition may be useful in the clinical evaluation of these patients...
- Prediction equations for normal and low lung function from the Health Survey for EnglandE Falaschetti
Dept of Epidemiology and Public Health, Royal Free and University College Medical School, London, UK
Eur Respir J 23:456-63. 2004..It is, therefore, suggested that these newly developed prediction equations be used for the White English population in both epidemiological studies and clinical practice...
- Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteriaMarc Estenne
Erasme University Hospital, Brussels, Belgium
J Heart Lung Transplant 21:297-310. 2002
- An official American Thoracic Society/European Respiratory Society statement: pulmonary function testing in preschool childrenNicole Beydon
Am J Respir Crit Care Med 175:1304-45. 2007
- Early identification of small airways disease on lung cancer screening CT: comparison of current air trapping measuresOnno M Mets
Department of Radiology, University Medical Centre Utrecht, Heidelberglaan 100, HP E01 132, Postbus 85500, 3508 GA, Utrecht, The Netherlands
Lung 190:629-33. 2012..We studied which of the currently suggested measures is most suitable for detecting functionally relevant air trapping on low-dose computed tomography (CT) in a population of subjects with early-stage disease...
- Sex differences in severe pulmonary emphysemaFernando J Martinez
University of Michigan, Division of Pulmonary and Critical Care Medicine, Ann Arbor, Michigan 48109 0360, USA
Am J Respir Crit Care Med 176:243-52. 2007..Limited data on sex differences in advanced COPD are available...
- Outcome measures in chronic obstructive pulmonary disease (COPD): strengths and limitationsThomas Glaab
Pulmonary Department, University Hospital, Johannes Gutenberg University, Mainz, Germany
Respir Res 11:79. 2010....
- A comparison of the level of dyspnea vs disease severity in indicating the health-related quality of life of patients with COPDT Hajiro
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan
Chest 116:1632-7. 1999..To compare categorizations of the level of dyspnea with the staging of disease severity as defined by the FEV(1) in representing how the health-related quality of life (HRQOL) is distributed in patients with COPD...
- Exercise pathophysiology in patients with primary pulmonary hypertensionX G Sun
Department of Medicine, Harbor-UCLA Medical Center, Torrance, California, USA
Circulation 104:429-35. 2001..CONCLUSIONS: Patients with PPH can safely undergo noninvasive cycle ergometer CPET to their maximal tolerance. The CPET abnormalities were consistent and characteristic and correlated well with NYHA class...
- Genetic ancestry in lung-function predictionsRajesh Kumar
Division of Allergy and Immunology, Children s Memorial Hospital, 2300 Children s Plaza, Box 60, Chicago IL 60614, USA
N Engl J Med 363:321-30. 2010....
- A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosisGanesh Raghu
Division of Pulmonary Medicine, University of Washington, Seattle 98195, USA
N Engl J Med 350:125-33. 2004..Idiopathic pulmonary fibrosis is a progressive, fatal disease with no known efficacious therapy...
- Efficacy and safety of budesonide and formoterol in one pressurized metered-dose inhaler in patients with moderate to very severe chronic obstructive pulmonary disease: results of a 6-month randomized clinical trialDonald P Tashkin
Division of Pulmonary and Critical Care Medicine, University of California, Los Angeles, California, USA
Drugs 68:1975-2000. 2008..Budesonide/formoterol dry powder inhaler (DPI) has demonstrated efficacy and tolerability in patients with COPD...
- Exercise anaerobic threshold and ventilatory efficiency identify heart failure patients for high risk of early deathAnselm K Gitt
Herzzentrum Ludwigshafen, Department of Cardiology, Ludwigshafen, Germany
Circulation 106:3079-84. 2002..Thus, we compared these parameters with peak VO2 in identifying patients with CHF at increased risk for death within 6 months after evaluation...
- Cyclophosphamide versus placebo in scleroderma lung diseaseDonald P Tashkin
University of California at Los Angeles, Los Angeles, USA
N Engl J Med 354:2655-66. 2006....
- Clinical significance of radiologic characterizations in COPDMeiLan K Han
University of Michigan Health System, Ann Arbor, Michigan 48109 5360, USA
COPD 6:459-67. 2009..Future research should clarify whether CT parameters complement BODE score in influencing survival...
- Evaluation of respiratory impedance in asthma and COPD by an impulse oscillation systemShintarou Kanda
The First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan
Intern Med 49:23-30. 2010..The purpose of this study was to clarify the differences in physiological properties of the airways between asthma and COPD using an impulse oscillation system (IOS)...
- Measurement of breathlessness in advanced disease: a systematic reviewC Bausewein
Department of Palliative Care, Policy and Rehabilitation, King s College London, Weston Education Centre, Denmark Hill, Cutcombe Road, London SE5 9RJ, UK
Respir Med 101:399-410. 2007..The aim of this systematic review was to identify all measures available via standard search techniques and review their usefulness for patients with advanced disease...
- Serum CC-chemokine ligand 18 concentration predicts outcome in idiopathic pulmonary fibrosisAntje Prasse
Department of Pneumology, University Freiburg, Germany
Am J Respir Crit Care Med 179:717-23. 2009..Conclusive data for any serum biomarker are lacking. We have recently documented that serum CCL18 concentrations correlate with the course of pulmonary function data in patients with pulmonary fibrosis of various causes...
- Increased sputum and bronchial biopsy IL-13 expression in severe asthmaShironjit K Saha
Institute for Lung Health, Clinical Sciences Wing, University Hospitals of Leicester, Leicester, United Kingdom
J Allergy Clin Immunol 121:685-91. 2008..The importance of IL-13 in the asthma paradigm is supported by increased expression in human subjects, particularly in patients with mild-to-moderate asthma. However, the role of IL-13 in severe asthma needs to be further defined...
- Fibrotic idiopathic interstitial pneumonia: the prognostic value of longitudinal functional trendsPanagiota I Latsi
Interstitial Lung Disease Unit, Emmanuel Kaye Building, Manresa Road, Chelsea, London SW6 LR6, UK
Am J Respir Crit Care Med 168:531-7. 2003..Their histologic distinction provides no additional prognostic information when pulmonary function trends are clear cut or when functional impairment is severe...
- Clinical analysis of chronic obstructive pulmonary disease phenotypes classified using high-resolution computed tomographyKeisaku Fujimoto
1st Department of Internal Medicine, Shinsu University School of Medicine, Matsumoto, Japan
Respirology 11:731-40. 2006....
- Risk factors for airway remodeling in asthma manifested by a low postbronchodilator FEV1/vital capacity ratio: a longitudinal population study from childhood to adulthoodFinn Rasmussen
Firestone Institute for Respiratory Health, St Joseph s Hospital and McMaster University, Hamilton, Ontario, Canada
Am J Respir Crit Care Med 165:1480-8. 2002..These data suggest that airway remodeling in asthma, as manifested by impaired lung function, begins in childhood and continues into adult life...
- Interstitial lung disease guideline: the British Thoracic Society in collaboration with the Thoracic Society of Australia and New Zealand and the Irish Thoracic SocietyB Bradley
Royal Infirmary Edinburgh, Little France Crescent, Edinburgh EH16 4SA, UK
Thorax 63:v1-58. 2008
- The forced oscillation technique in clinical practice: methodology, recommendations and future developmentsE Oostveen
Dept of Pulmonary Medicine, University Hospital Antwerp, Belgium
Eur Respir J 22:1026-41. 2003..Novel applications of forced oscillation technique in the clinical setting include the monitoring of respiratory mechanics during mechanical ventilation and sleep...
- Serum biomarkers as predictors of lung function decline in chronic obstructive pulmonary diseaseYuji Higashimoto
Department of Respiratory Medicine and Allergology, Kinki University School of Medicine, 377 2 Ohnohigashi, Osakasayama, Osaka, 589 8511 Japan
Respir Med 103:1231-8. 2009..We examined correlations between serum biomarkers and the decline of lung function in COPD patients...
- Forced spirometry reference values for Norwegian adults: the Bronchial Obstruction in Nord-TrÃ¸ndelag StudyA Langhammer
, The Norwegian University of Science and Technology (NTNU, Verdal
Eur Respir J 18:770-9. 2001..Healthcare providers should be encouraged to reconsider their choice of prediction equations of spirometry in order to improve management of obstructive lung diseases...
- The progression of chronic obstructive pulmonary disease is heterogeneous: the experience of the BODE cohortCiro Casanova
Pulmonary Department, Hospital Universitario La Candelaria, Tenerife, Spain
Am J Respir Crit Care Med 184:1015-21. 2011..Chronic obstructive pulmonary disease (COPD) is thought to result in rapid and progressive loss of lung function usually expressed as mean values for whole cohorts...
- Threshold effect of urinary glycosaminoglycans and the walk test as indicators of disease progression in a survey of subjects with Mucopolysaccharidosis VI (Maroteaux-Lamy syndrome)Stuart J Swiedler
BioMarin Pharmaceutical Inc, Novato, California, USA
Am J Med Genet A 134:144-50. 2005..Pending the collection of longitudinal data, these results suggest that urinary GAG levels predict clinical morbidity, and longer-term survival is associated with urinary GAG levels below a threshold of 100 mug/mg creatinine...
- Abdominal obesity and respiratory function in men and women in the EPIC-Norfolk Study, United KingdomD Canoy
Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
Am J Epidemiol 159:1140-9. 2004..In the general adult population, abdominal fat deposition may play a role in the impairment of respiratory function among the abdominally obese...
- MDCT assessment of airway wall thickness in COPD patients using a new method: correlations with pulmonary function testsTobias Achenbach
Department of Diagnostic and Interventional Radiology, Johannes Gutenberg University, Langenbeckstrasse 1, 55101, Mainz, Germany
Eur Radiol 18:2731-8. 2008..In COPD patients, the wall thickness measured as a mean for a given patient correlated with the values of FEV1 and FEV1% predicted. Correlation with FEV1 was higher when only small airways were considered...
- Validation of the clinical COPD Questionnaire (CCQ) in primary careBjorn Stallberg
Department of Public Health and Caring Sciences, Section of Family Medicine and Clinical Epidemiology, Uppsala University, Uppsala, Sweden
Health Qual Life Outcomes 7:26. 2009..The newly developed, short Clinical COPD Questionnaire, CCQ, was therefore validated against the St George's Respiratory Questionnaire (SGRQ)...
- Idiopathic pulmonary fibrosis: physiologic tests, quantitative CT indexes, and CT visual scores as predictors of mortalityAlan C Best
Department of Radiology, University of Colorado Denver, 4200 E 9th Ave, Denver, CO 80262, USA
Radiology 246:935-40. 2008....
- Oxidative status in the lungs associated with tobacco smoke exposureSibel Doruk
Department of Pulmonary Medicine, Gaziosmanpasa University Faculty of Medicine, Tokat, Turkey
Clin Chem Lab Med 49:2007-12. 2011..We aimed to investigate oxidative stress in the lungs associated with TS and to evaluate the effect of this stress with pulmonary function tests (PFTs)...
- Chronic obstructive pulmonary disease: thin-section CT measurement of airway wall thickness and lung attenuationIlaria Orlandi
Radiodiagnostic Section, Department of Clinical Physiopathology, University of Florence, Viale Morgagni 85, Florence 50134, Italy
Radiology 234:604-10. 2005....
- Invasive and noninvasive lung function measurements in rodentsHeinz Gerd Hoymann
Fraunhofer Institute of Toxicology and Experimental Medicine ITEM, Nikolai Fuchs Str 1, Hannover, Germany
J Pharmacol Toxicol Methods 55:16-26. 2007....
- Respiratory and skeletal muscle strength in chronic obstructive pulmonary disease: impact on exercise capacity and lower extremity functionJonathan Singer
Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California, San Francisco, California 94143, USA
J Cardiopulm Rehabil Prev 31:111-9. 2011..We sought to quantify the impact of respiratory muscle and lower extremity strength on exercise capacity and lower extremity function (LEF) in patients with chronic obstructive pulmonary disease (COPD)...
- Predictive equations for lung function based on a large occupational population in North ChinaYonghui Wu
Department of Occupational Health, School of Public Health, Harbin Medical University, PR China
J Occup Health 51:471-7. 2009..The currently used predictive equations of lung function in North China were derived from early study and have not been updated for nearly two decades...
- Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screeningPeter D Sly
Division of Clinical Sciences, Telethon Institute for Child Health Research, PO Box 855, W Perth, WA 6872, Australia
Am J Respir Crit Care Med 180:146-52. 2009..The promise of newborn screening (NBS) for cystic fibrosis (CF) has not been fully realized, and the extent of improvement in respiratory outcomes is unclear. We hypothesized that significant lung disease was present at diagnosis...
- Lung clearance index in the assessment of airways diseaseAlex Horsley
Department of Respiratory Medicine, Edinburgh Royal Infirmary, 51 Little France Crescent, Edinburgh EH4 2XU, United Kingdom
Respir Med 103:793-9. 2009..Thorax, 2008;63(2):96-7]. This review will consider how LCI is derived, how it differs from conventional lung function testing, and its applications and limitations...
- Cutting edge technologies in respiratory research: lung function testingGregory G King
Woolcock Institute of Medical Research, The Northern Clinical School, Sydney Medical School, University of Sydney, New South Wales, Australia
Respirology 16:883-90. 2011..Optical coherence tomography, optical reflection, electrical impedance and vibration response imaging have arisen by development of novel devices. The recent use of these techniques is reviewed...
- Pulmonary tuberculosis, impaired lung function, disability and quality of life in a high-burden settingG P Maguire
International Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia
Int J Tuberc Lung Dis 13:1500-6. 2009..Tuberculosis treatment clinic in Papua, Indonesia...
- Serial measurements of lung function in a cohort of young children with bronchopulmonary dysplasiaKhoulood F Fakhoury
Pulmonary Section, Department of Pediatrics, Baylor College of Medicine, Texas Children s Hospital, Houston, TX 77030, USA
Pediatrics 125:e1441-7. 2010..We aimed to prospectively and longitudinally measure lung function in a cohort of children with bronchopulmonary dysplasia (BPD) during their first 3 years of life...
- The influence of gastroesophageal reflux in the lung: a case-control studyKornelija Mise
Clinical Department for Respiratory Diseases, Split University Hospital, Split, Croatia
Respirology 15:837-42. 2010..We also wished to determine whether an acidic environment in the lung influences pulmonary function and DL(CO), and whether microaspiration of gastric contents directly influences non-specific inflammation in the lung...
- Risk factors for chronic obstructive pulmonary disease in a European cohort of young adultsRoberto de Marco
Department of Public Health and Community Medicine, University of Verona, Istituti Biologici II, Verona, Italy
Am J Respir Crit Care Med 183:891-7. 2011..Few studies have investigated the factors associated with the early inception of chronic obstructive pulmonary disease (COPD)...
- Effect of acute hypoxia on respiratory muscle fatigue in healthy humansSamuel Verges
HP2 laboratory INSERM ERI17, Joseph Fourier University, Grenoble University Hospital, Grenoble, France
Respir Res 11:109. 2010..Hence, we assessed the effect of different blood oxygenation level on isolated hyperpnoea-induced inspiratory and expiratory muscle fatigue...
- Chronic obstructive pulmonary disease diagnosis and management in older adultsNalaka S Gooneratne
Division of Geriatric Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
J Am Geriatr Soc 58:1153-62. 2010..Clinicians caring for older adults with an acute COPD exacerbation should also guard against prognostic pessimism. Although COPD is associated with significant disability, there is a growing range of treatment options to assist patients...
- Sputum eosinophilia can predict responsiveness to inhaled corticosteroid treatment in patients with overlap syndrome of COPD and asthmaYoshiaki Kitaguchi
First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan
Int J Chron Obstruct Pulmon Dis 7:283-9. 2012..It was hypothesized that patients with overlap syndrome may have different clinical characteristics such as sputum eosinophilia, and better responsiveness to treatment with inhaled corticosteroid (ICS)...
- Body mass index may modify asthma prevalence among low-birth-weight childrenFrank Leigh Lu
Division of Pediatric Pulmonology and Critical Care Medicine, Department of Pediatrics, National Taiwan University Hospital and National Taiwan University Medical College, Taipei, Taiwan
Am J Epidemiol 176:32-42. 2012..05). Low birth weight predisposes one to develop asthma, and excess body mass amplifies the risk. A sex difference was observed. This study suggests that prenatal care and nutritional counseling could reduce asthma prevalence...
- Spirometric predictors of lung function decline and mortality in early chronic obstructive pulmonary diseaseM Bradley Drummond
Division of Pulmonary Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
Am J Respir Crit Care Med 185:1301-6. 2012..The course of lung function decline for smokers with early airflow obstruction remains undefined. It is also unclear which early spirometric characteristics identify individuals at risk for rapid decline and increased mortality...
- Lung clearance index at 4 years predicts subsequent lung function in children with cystic fibrosisPaul Aurora
Portex Respiratory Unit, UCL Institute of Child Health, 30 Guilford St, London WC1N 1EH, UK
Am J Respir Crit Care Med 183:752-8. 2011..There is an urgent need for alternative surrogates that detect early lung disease and track through early childhood...
- Cardiopulmonary exercise testing characteristics in heart failure patients with and without concomitant chronic obstructive pulmonary diseaseMarco Guazzi
Cardiopulmonary Laboratory, Cardiology Division, University of Milano, San Paolo Hospital, Milano, Italy
Am Heart J 160:900-5. 2010....
- Inhaled corticosteroids or long-acting beta-agonists alone or in fixed-dose combinations in asthma treatment: a systematic review of fluticasone/budesonide and formoterol/salmeterolChristian Frois
Analysis Group, Boston, Massachusetts 02199 7636, USA
Clin Ther 31:2779-803. 2009..Inhaled corticosteroids (ICSs) and long-acting inhaled beta(2)-agonists (LABAs) are recommended treatment options for asthma...
- Chronic obstructive pulmonary disease: CT quantification of airways diseaseMaxime Hackx
Department of Radiology, Hopital Erasme, Universite Libre de Bruxelles, 808 Route de Lennik, 1070 Brussels, Belgium
Radiology 265:34-48. 2012..This article details these three approaches and concludes with perspectives and directions for further research...
- Reference values for lung function: past, present and futureS Stanojevic
Portex Respiratory Physiology Unit, UCL Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK
Eur Respir J 36:12-9. 2010..We aim to highlight some of the main issues in selecting and using reference equations and discuss how recent developments may improve interpretation of pulmonary function results...
- Interpreting lung function data using 80% predicted and fixed thresholds identifies patients at increased risk of mortalityDavid M Mannino
Department of Preventive Medicine and Environmental Health, University of Kentucky College of Public Health, 121 Washington Ave, Lexington, KY 40536, USA
Chest 141:73-80. 2012..This study investigated mortality in a representative sample of the US adult population with COPD by comparing abnormality determined using GOLD criteria to that determined using LLN criteria...
- The chronic bronchitic phenotype of COPD: an analysis of the COPDGene StudyVictor Kim
Temple University School of Medicine, Philadelphia, PA 19140, USA
Chest 140:626-33. 2011..Despite its clinical significance, the chronic bronchitic phenotype in COPD remains poorly defined...
- Exposure to wood smoke particles produces inflammation in healthy volunteersAndrew J Ghio
The National Health and Environmental Effects Research Laboratory, US EPA, Research Triangle Park, North Carolina, USA
Occup Environ Med 69:170-5. 2012..This investigation tested the postulate that healthy volunteers exposed to WSP would demonstrate evidence of both pulmonary and systemic inflammation...
- Impaired respiratory function in mdx and mdx/utrn(+/-) micePing Huang
Department of Neurology, Cleveland Clinic, Cleveland, OH 44195, USA
Muscle Nerve 43:263-7. 2011..The mdx/utrn(+/-) mouse model may be better than the mdx model for testing antifibrotic therapies, especially at the severe stage...
- Two novel mutations in surfactant protein-C, lung function and obstructive lung diseaseMarie Baekvad-Hansen
Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Faculty of Health Sciences, Herlev Ringvej 75, DK 2730 Herlev, Copenhagen, Denmark
Respir Med 104:418-25. 2010..A53T heterozygotes had increased asthma risk, but further research is required to conclusively determine whether this mutation is associated with asthma...
- Association between combined interleukin-6 and C-reactive protein levels and pulmonary function in older women: results from the Women's Health and Aging Studies I and IISANDY S CHANG
Section of Geriatrics, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
J Am Geriatr Soc 59:113-9. 2011....
- Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samplesKatherine J Baines
Centre for Asthma and Respiratory Diseases, Hunter Medical Research Institute, University of Newcastle, Callaghan, Australia
J Allergy Clin Immunol 127:153-60, 160.e1-9. 2011..Previous studies have identified clinical or inflammatory phenotypes of asthma on the basis of clinical and demographic parameters or sputum cell counts; however, few studies have defined transcriptional phenotypes of asthma...
- Elevated plasma ghrelin level in underweight patients with chronic obstructive pulmonary diseaseTakefumi Itoh
Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center Research Institute, 5 7 1 Fujishirodai, Suita, Osaka 565 8565, Japan
Am J Respir Crit Care Med 170:879-82. 2004..In conclusion, plasma ghrelin was elevated in underweight patients with chronic obstructive pulmonary disease, and the level was associated with a cachectic state and abnormality of pulmonary function...
- Relationship between airway wall thickness assessed by high-resolution computed tomography and lung function in patients with asthma and chronic obstructive pulmonary diseaseJ Kosciuch
Department of Internal Medicine, Pneumology and Allergology, Medical University of Warsaw, Poland
J Physiol Pharmacol 60:71-6. 2009..In COPD, the thickening of airway wall also is related to exposure to tobacco smoke...
- Do family physicians' records fit guideline diagnosed COPD?Mieke Albers
Department of Primary Care Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Fam Pract 26:81-7. 2009..In family practice, chronic obstructive pulmonary disease (COPD) is usually not diagnosed until clinically apparent and of moderately advanced severity...
- Induced sputum markers of fibrosis and decline in pulmonary function in asbestosis and silicosis: a pilot studyP Prince
Centre de Recherche de l Hopital Laval, Institut de cardiologie et de pneumologie de l Université Laval, Quebec, Canada
Int J Tuberc Lung Dis 12:813-9. 2008..To evaluate the usefulness of fibrogenic cytokines and mediators in the analysis of induced sputum and determine if their levels correlated with previous decline in lung function in asbestosis and silicosis...
- Lung volume, breathing pattern and ventilation inhomogeneity in preterm and term infantsPhilipp Latzin
Division of Respiratory Medicine, Department of Paediatrics, Inselspital and University of Bern, Bern, Switzerland
PLoS ONE 4:e4635. 2009..Although some studies have shown lower lung volumes and increased ventilation inhomogeneity in BPD infants, conflicting results exist possibly due to differences in sedation and measurement techniques...
- Telomere shortening in chronic obstructive pulmonary diseaseJoyce M J Houben
Department of Health Risk Analysis and Toxicology, University of Maastricht, The Netherlands
Respir Med 103:230-6. 2009..05). These data provide evidence for a relationship between a disturbed oxidant/antioxidant balance and telomere shortening and indicate that preservation of fat mass may be protective in delaying telomere shortening in COPD patients...
- Airway inflammation in cystic fibrosisArnon Elizur
Department of Pediatrics, Assaf Harofeh Medical Center, Zerifin, Israel
Chest 133:489-95. 2008..Strategies for modulating the airway inflammation in patients with CF are currently under development and may offer new therapeutic options for these patients...
- No increase in the prevalence of COPD in two decadesT M Vasankari
Dept of Respiratory Medicine, Turku University Hospital, PL 52, FI 20521, Turku, Finland
Eur Respir J 36:766-73. 2010..In conclusion, no significant difference was found in the prevalence of COPD stages II-IV between similar population based surveys performed 20 yrs apart. Since COPD is mostly mild or moderate there is a strong case for early prevention...
- Sex differences in emphysema and airway disease in smokersPat G Camp
James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, St Paul s Hospital, Vancouver, BC, Canada
Chest 136:1480-8. 2009..The purpose of this study was to test for sex differences in COPD phenotypes by using high-resolution CT (HRCT) scanning in male and female smokers with and without COPD...
- Early pulmonary involvement in ankylosing spondylitis: assessment with thin-section CTK Turetschek
Department of Radiology, University of Vienna, Austria
Clin Radiol 55:632-6. 2000....
- Association of increased CCL5 and CXCL7 chemokine expression with neutrophil activation in severe stable COPDA Di Stefano
Division of Pulmonary Disease and Laboratory of Cytoimmunopathology of Heart and Lung, Salvatore Maugeri Foundation, IRCCS, Veruno, Italy
Thorax 64:968-75. 2009..Increased numbers of activated neutrophils have been reported in the bronchial mucosa of patients with stable chronic obstructive pulmonary disease (COPD), particularly in severe disease...
- Prevalence of airflow obstruction in smokers and never-smokers in SwitzerlandP O Bridevaux
Division of Pulmonary Medicine, University Hospitals of Geneva, Geneva
Eur Respir J 36:1259-69. 2010..Never-smokers account for a third of the prevalence, which is higher proportion than elsewhere. Airflow obstruction in never-smokers deserves attention because of its frequency and its similar health impact to that in smokers...
- Bronchiectasis in infants and preschool children diagnosed with cystic fibrosis after newborn screeningStephen M Stick
Department of Respiratory Medicine, Princess Margaret Hospital for Children, School of Paediatrics and Child Health, University of Western Australia, Melbourne, Australia
J Pediatr 155:623-8.e1. 2009..To determine the prevalence of bronchiectasis in young children with cystic fibrosis (CF) diagnosed after newborn screening (NBS) and the relationship of bronchiectasis to pulmonary inflammation and infection...
- Progressive preclinical interstitial lung disease in rheumatoid arthritisBernadette R Gochuico
Pulmonary Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, MSC 1590, Bethesda, MD 20892 1590, USA
Arch Intern Med 168:159-66. 2008..The objective of this study was to identify asymptomatic lung disease and potential therapeutic targets in patients having RA and preclinical ILD (RA-ILD)...
- Functional status measurement in COPD: a review of available methods and their feasibility in primary careJanwillem W H Kocks
Department of General Practice, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Prim Care Respir J 20:269-75. 2011..This review aims to categorize systematically the available tools based on their construct (i.e. what the tool intends to measure) and to rate the tools for use in the primary care setting...
- Pulmonary involvement in patients with early rheumatoid arthritisZ M Metafratzi
Department of Clinical Radiology and Imaging, Medical School of Patras, Greece
Scand J Rheumatol 36:338-44. 2007..To assess the pleuropulmonary changes in patients with early rheumatoid arthritis (RA), using high-resolution computed tomography (HRCT)...
- The influence of air pollution mixtures on biomarkers of airway oxidative stressRoby Greenwald; Fiscal Year: 2013..In addition, we will actively engage in a process of biomarker discovery and evaluation. ..
- VitC to Decrease Effects of Smoking in Pregnancy on Infant Lung Function-CCC-LeadCYNTHIA T MCEVOY; Fiscal Year: 2013..End of Abstract) ..
- VitC to Decrease Effects of Smoking in Pregnancy on Infant Lung Function-DCCCynthia D Morris; Fiscal Year: 2013..This research has great public health significance to potentially alter the fetal origins of respiratory disease by blocking some of the effects of in-utero smoke exposure on lung development. ..
- Modulation of Genes Responsible for Cilia Length by Exposure to Cigarette SmokeAnn E Tilley; Fiscal Year: 2013..An understanding of one of the mechanisms underlying dysfunctional mucociliary clearance in smokers may lead to targets for therapeutic intervention. ..
- Novel Protective Antiapoptotic Action of Alpha 1-Antitrypsin In EmphysemaRubin M Tuder; Fiscal Year: 2011..abstract_text> ..
- XeBox-E10 Gas Polarizer for Functional MRI of Pediatric Lung DiseaseSEAN BEDILION FAIN; Fiscal Year: 2013..To apply ventilation/perfusion MRI to clinical research investigations of early disease in asthma, CF, and BPD, while supporting ongoing studies of adult lung disease and expansion to new opportunities. ..
- Imaging regional physiologic parameters of lung functionRahim R Rizi; Fiscal Year: 2011....
- Community Assessment of Freeway Pollution and HealthDoug Brugge; Fiscal Year: 2012....
- Ph2 of T-Cell Depl Familial Haploidentical SCT for tx Hi-Risk Sickle Cell AnemiaMitchell S Cairo; Fiscal Year: 2013..abstract_text> ..
- HIV and COPD:Immune mediated mechanismsBenjamin D Medoff; Fiscal Year: 2013....
- Quantitative Structural and Functional Imaging of the LungRahim R Rizi; Fiscal Year: 2013..These novel markers will significantly improve understanding of COPD and will be critical to characterizing disease response to therapy. ..
- Normal Tissue Complication Modeling for RadiotherapyJoseph Deasy; Fiscal Year: 2009....
- Fibroblast Cell Signaling in Utero Nicotine-Induced Lung InjuryVirender K Rehan; Fiscal Year: 2012....
- High-Resolution MicroCT Scanner for Cardiopulmonary Imaging ApplicationsRahim R Rizi; Fiscal Year: 2010..Important clinical applications include diagnosis of tumors and other pathologies in various application areas including pulmonary, cardiac, biomechanics and cancer tumors. ..
- Late Preterm Birth, Ureaplasma Species and Childhood Lung DiseaseSuhas Kallapur; Fiscal Year: 2012..abstract_text> ..
- Stability of Pullmonary AirwaysJAMES BERNARD GROTBERG; Fiscal Year: 2010....
- Optimization of Hyperpolarized Xenon-129 Diffusion MRI for COPDChengbo Wang; Fiscal Year: 2013..This will lay the foundation for future clinical trials to evaluate the potential of HP 129Xe diffusion MRI as a fundamentally improved approach for staging and monitoring progression of COPD. ..
- An integrative statistics-guided image-based multi-scale lung modelChing Long Lin; Fiscal Year: 2013..Human subject studies will be conducted using volumetric 3D lung dual energy computed tomography (DECT) and 99mTc-MPAO-labelled white blood cell (WBC) lung SPECT imaging for model validation and longitudinal studies. ..
- Regional Quantification of Lung Function in Cystic Fibrosis using Xe129 MRIJaime Mata; Fiscal Year: 2013..All subjects under this aim will also receive full pulmonary function tests (PFTs) to evaluate the degree of disease severity and to correlate with the results from 3D SB-CSI. ..
- Regional Lung Mechanics by 3D Image RegistrationJoseph M Reinhardt; Fiscal Year: 2010..This information is now critical to the development and evaluation of new pulmonary disease therapies. ..
- CT-based Biomarker for Diagnosis of COPD Phenotypes and Disease ProgressionCraig J Galban; Fiscal Year: 2013..Overall, it is anticipated that the successful outcome of this effort will significanty improve the diagnostic capability of CT imaging for COPD, leading to improved patient care and a reduction in cost to the healthcare system. ..
- Radiation-Induced Cardiopulmonary Injury in HumansLawrence B Marks; Fiscal Year: 2012..This information will lead to algorithms that accurately predict the risk of cardiopulmonary injury, facilitate the design of "safer" 3D dose distributions, and thus improve patient care. ..
- Exposure-induced Systemic Oxidative Stress in Children with AsthmaMELINDA SUE BUTSCH KOVACIC; Fiscal Year: 2010..Consequently, these and planned future efforts will underscore the importance of environmental exposures in asthma treatment, development of diagnostic tools and new evidenced-based environmental policies. ..
- Reducing Dynamic Hyperinflation through Breathing RetrainingEileen G Collins; Fiscal Year: 2013..Multiple regression analysis will be employed to determine the predictors of improved exercise performance. ..
- Couple-Based Mind-Body Program for Lung Cancer Patients and their PartnersKathrin Milbury; Fiscal Year: 2013..The training and research activities proposed in this application will help her become an independent researcher capable of obtaining such grant support. ..
- DIET AND CHRONIC OBSTRUCTIVE PULMONARY DISEASECarlos Camargo; Fiscal Year: 2002..The proposed study is cost-effective, as it makes use of an existing cohort, and it will provide information that could have direct clinical application to reduce risk of COPD. ..
- EPIDEMIOLOGY OF IMMUNOLOGIC LUNG DISEASEKathleen Kreiss; Fiscal Year: 1991..This proposal is the critical step in development of a screening test for the prevention of beryllium disease among the 800,000 Americans who have had industrial exposure to beryllium...
- Very-short-time diffusion MRI of hyperpolarized gasesG Miller; Fiscal Year: 2009..Application of these methods may be used for early detection of serious lung diseases such as emphysema and will provide a tool for medical researchers to better investigate the causes and potential treatments of lung disease. ..
- Bronchial Reactivity and the Course of Lung Function After WTC ExposureThomas K Aldrich; Fiscal Year: 2013..The results should define the natural history of WTC-associated OAD, determine whether clinical outcomes varied according to bronchial reactivity, assess the influence of anti- inflammatory treatment on outcomes. ..
- IMMUNE REGULATION IN LUNG TRANSPLANTATIONWILLIAM BURLINGHAM; Fiscal Year: 2003..We will determine how the sensitivity, specificity, and predictive value of each test would be clinically useful in the management of lung transplant patients. ..
- Imaging Regional Physiological and Structural Parameters of Airway RemodelingKiarash Emami; Fiscal Year: 2009..Assessment of the sensitivity of these techniques to airway remodeling induced by a murine model of asthma, compared to conventional pulmonary function tests, and validation of measurements against histological gold standard markers. ..
- Mentored Patient-Oriented Research Career Development AwardRuey Kang Chang; Fiscal Year: 2006..The principal investigator will take advanced courses to enhance knowledge and skills needed for patient-oriented research and work with the mentors to conduct the proposed project during the award period. ..
- Development of Hyperpolarized Helium for Assessing ILDMilton Rossman; Fiscal Year: 2009..We believe that these measurements can differentiate inflammatory from fibrotic DPLD and will have important diagnostic and prognostic utility in humans ..
- RADIATION INDUCED WHOLE & REGIONAL LUNG INJURY IN HUMANSLawrence Marks; Fiscal Year: 2000..While not part of this study, patients enrolled onto this protocol will be included in parallel biological studies designed to consider the molecular biological mechanisms of radiation-induced lung injury. ..
- IMPACT OF AEROSOL CYCLOSPORINE IN LUNG TRANSPLANTATIONAdriana Zeevi; Fiscal Year: 2002..abstract_text> ..
- IMMUNOTHERAPY OF CHILDHOOD ASTHMAN Adkinson; Fiscal Year: 1993..Finally, the effect of high-dose, long-term immunotherapy on parameters of target cell sensitivity in children will be examined...
- Standardized Indices of BreathlessnessJohn Baird; Fiscal Year: 2007..The overall goal is to further our understanding about these diseases and to identify better clinical outcome measures. [unreadable] [unreadable] [unreadable]..
- R21 PROJECT--EFFICACY OF OSTEOPATHIC MANIPULATION IN COPDONALD NOLL; Fiscal Year: 2001..abstract_text> ..
- APD to Measure the Resistance of the Respiratory SystemJAFAR VOSSOUGHI; Fiscal Year: 2004..In Phase I work we plan to further develop the system to be battery-operated, low weight, portable, and less expensive. It will be clinically tested on at least 200 individuals. ..
- Antibiotics in Infancy-Risk Factor for Childhood AsthmaDennis Ownby; Fiscal Year: 2002..This new analysis will allow a much more rigorous examination of the possible relationship between early antibiotic use and asthma in a population of American children. ..
- Association Between Asthma and Helminthic InfectionsMaria Araujo; Fiscal Year: 2004....
- RANDOMIZED TRIAL OF REHABILITATION IN COPDRobert Kaplan; Fiscal Year: 1992..Using the quality of life outcome data and data obtained on costs, we will construct a policy model evaluating the cost/utility of the rehabilitation interventions...
- YOGA AND PEAK FLOW RATES IN PREGNANT ASTHMATICSJudith Balk; Fiscal Year: 2000..The study is designed as an intent to treat trial, however compliance will be assessed by a prospectively gathered diary which will be blinded until the end of the study. ..
- YOGA AND PEAK FLOW RATES IN PREGNANT ASTHMATICSJudith Balk; Fiscal Year: 2002..The study is designed as an intent to treat trial, however compliance will be assessed by a prospectively gathered diary which will be blinded until the end of the study. ..
- Genetic studies in difficult to treat asthma: TENOREugene Bleecker; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Noninvasive Ventilation in Children with Cystic FibrosisCAROLE MARCUS; Fiscal Year: 2004..In keeping with the mission of the RFA, this study will use a multidisciplinary approach to improve management and enhance the quality of life in children with chronic respiratory failure. ..
- LUNG HEALTH STUDY--LONG TERM FOLLOW UPRobert Wise; Fiscal Year: 2002..All ten of the original LHS clinical centers plan to participate. To minimize bias, all surviving participants of the LHS will be invited to participated, giving a potential sample size of 5600. ..
- MULTIPLE GAS MEASUREMENT OF LUNG TISSUE VOLUMEGEORGE SWANSON; Fiscal Year: 1980..Theoretical studies will assess the reliability of the technique in maldistribution and the possibility of assessing an index of maldistribution. ..
- LUNG PARAMETERS FROM RESPIRATORY IMPEDANCE MEASUREMENTSAndrew Jackson; Fiscal Year: 1992..2 -200 Hz in healthy and sick children ages 42 months to 18 years. The statistical reliability and physiological appropriateness of parameters in inverse models applied to such data will be determined...
- PHYSICAL GROWTH IN PATIENTS WITH CYSTIC FIBROSISPAMELA BYARD; Fiscal Year: 1990....
- LUNG HEALTH STUDY--LONG TERM FOLLOW-UP DATA COORD CTRJohn Connett; Fiscal Year: 2002....
- LUNG HEALTH STUDY--LONG TERM FOLLOW-UPRobert Rogers; Fiscal Year: 2002..All ten of the original LHS clinical centers plan to participate. To minimize bias, all surviving participants of the LHS will be invited to participate, giving a potential sample size of 5600. ..
- LUNG HEALTH STUDY--LONG TERM FOLLOW UPMURRAY ALTOSE; Fiscal Year: 2002..All ten of the original LHS clinical centers plan to participate. To minimize bias, all surviving participants of the LHS will be invited to participate, giving a potential sample size of 5600. ..
- LUNG HEALTH STUDY--LONG TERM FOLLOW-UPMichael Eichenhorn; Fiscal Year: 2002..All ten of the original LHS clinical centers plan to participate. To minimize bias, all surviving participants of the LHS will be invited to participate, giving a potential sample size of 5600. ..
- LUNG HEALTH STUDY--LONG TERM FOLLOW-UPALINE BUIST; Fiscal Year: 2002
- LUNG HEALTH STUDY--LONG TERM FOLLOW-UPPaul Scanlon; Fiscal Year: 2002
- LUNG HEALTH STUDY--LONG TERM FOLLOW UPNicholas Anthonisen; Fiscal Year: 2002
- LUNG HEALTH STUDY--LONG TERM FOLLOW-UPRICHARD KANNER; Fiscal Year: 2002..All ten of the original LHS clinical centers plan to participate. Of minimize bias, all surviving participants of the LHS will be invited to participate, giving a potential sample size of 5600. ..
- Tissue Tagging MRI of Regional Lung MechanicsQun Chen; Fiscal Year: 2007..unreadable] [unreadable]..
- MULTI-CNTER PHASE 2 TRIAL OF ORAL TYPE I BOVINE COLLAGEArnold Postlethwaite; Fiscal Year: 2000..In addition, studies are proposed to explore the underlying mechanisms that mediate a potential effect of oral collagen peptides in the immune pathogenesis of SSc. ..
- LUNG HEALTH STUDY--LONG TERM FOLLOW UPDonald Tashkin; Fiscal Year: 2002..All ten of the original LHS clinical centers plan to participate in this study. To minimize bias, all surviving participants of the LHS will be invited to participate, giving a potential sample size of 5600. ..
- SCLERODERMA LUNG STUDYDonald Tashkin; Fiscal Year: 2003..abstract_text> ..
- Distal Lung Inflammation Effect on Asthma ExacerbationsDonald Tashkin; Fiscal Year: 2008..This study has the potential to clarify the contribution of the "silent zone" to the persistent morbidity encountered with asthma. ..