polysomnography

Summary

Summary: Simultaneous and continuous monitoring of relevant normal and abnormal physiological activity during sleep. (Stedman, 25th ed)

Top Publications

  1. pmc Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults
    Lawrence J Epstein
    Sleep HealthCenters, Brighton, MA 02135, USA
    J Clin Sleep Med 5:263-76. 2009
  2. pmc Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin sleep cohort
    Terry Young
    Department of Population Health Sciences, University of Wisconsin Madison, Madison, WI, USA
    Sleep 31:1071-8. 2008
  3. pmc Behavioral and physiological consequences of sleep restriction
    Siobhan Banks
    Division of Sleep and Chronobiology, Department ofPsychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Clin Sleep Med 3:519-28. 2007
  4. ncbi Obstructive sleep apnoea and its cardiovascular consequences
    T Douglas Bradley
    Sleep Research Laboratory of the Toronto Rehabilitation Institute, Toronto, Canada
    Lancet 373:82-93. 2009
  5. ncbi Practice parameters for clinical use of the multiple sleep latency test and the maintenance of wakefulness test
    Michael R Littner
    VA Greater Los Angeles Healthcare System, CA, USA
    Sleep 28:113-21. 2005
  6. pmc Sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study
    Morten Engstrøm
    Department of Clinical Neurosciences, Norwegian University of Science and Technology, Trondheim, N 7489, Norway
    J Headache Pain 14:12. 2013
  7. ncbi Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study
    Naresh M Punjabi
    Division of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD21224, USA
    Am J Epidemiol 160:521-30. 2004
  8. ncbi Obstructive sleep apnea syndrome in the Sao Paulo Epidemiologic Sleep Study
    Sergio Tufik
    Disciplina de Medicina e Biologia do Sono, Departamento de Psicobiologia, Universidade Federal de Sao Paulo UNIFESP, Sao Paulo, Brazil
    Sleep Med 11:441-6. 2010
  9. ncbi The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation
    Hans P A Van Dongen
    Unit for Experimental Psychiatry, Division of Sleep and Chronobiology, Department of Psychiatry, and Centerfor Sleep and Respiratory Neurobiology, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
    Sleep 26:117-26. 2003
  10. ncbi Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure
    Takuya Yokoe
    First Department of Internal Medicine, Showa University, Tokyo, Japan
    Circulation 107:1129-34. 2003

Detail Information

Publications421 found, 100 shown here

  1. pmc Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults
    Lawrence J Epstein
    Sleep HealthCenters, Brighton, MA 02135, USA
    J Clin Sleep Med 5:263-76. 2009
    ..Obstructive sleep apnea (OSA) is a common chronic disorder that often requires lifelong care. Available practice parameters provide evidence-based recommendations for addressing aspects of care...
  2. pmc Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin sleep cohort
    Terry Young
    Department of Population Health Sciences, University of Wisconsin Madison, Madison, WI, USA
    Sleep 31:1071-8. 2008
    ..SDB is linked to incident cardiovascular disease, stroke, and other morbidity. However, the risk of mortality with untreated SDB, determined by polysomnography screening, in the general population has not been established.
  3. pmc Behavioral and physiological consequences of sleep restriction
    Siobhan Banks
    Division of Sleep and Chronobiology, Department ofPsychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Clin Sleep Med 3:519-28. 2007
    ....
  4. ncbi Obstructive sleep apnoea and its cardiovascular consequences
    T Douglas Bradley
    Sleep Research Laboratory of the Toronto Rehabilitation Institute, Toronto, Canada
    Lancet 373:82-93. 2009
    ..However, large-scale randomised trials are needed to determine, definitively, whether treating OSA improves cardiovascular outcomes...
  5. ncbi Practice parameters for clinical use of the multiple sleep latency test and the maintenance of wakefulness test
    Michael R Littner
    VA Greater Los Angeles Healthcare System, CA, USA
    Sleep 28:113-21. 2005
    ..These practice parameters also include recommendations for the MSLT and MWT protocols, a discussion of the normative data available for both tests, and a description of issues that need further study...
  6. pmc Sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study
    Morten Engstrøm
    Department of Clinical Neurosciences, Norwegian University of Science and Technology, Trondheim, N 7489, Norway
    J Headache Pain 14:12. 2013
    ..Our aim was to compare subjective and objective sleep quality and arousal in migraine and to evaluate the relationship between sleep quality and pain thresholds (PT) in controls, interictal, preictal and postictal migraine...
  7. ncbi Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study
    Naresh M Punjabi
    Division of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD21224, USA
    Am J Epidemiol 160:521-30. 2004
    ..The results of this study suggest that SDB is independently associated with glucose intolerance and insulin resistance and may lead to type 2 diabetes mellitus...
  8. ncbi Obstructive sleep apnea syndrome in the Sao Paulo Epidemiologic Sleep Study
    Sergio Tufik
    Disciplina de Medicina e Biologia do Sono, Departamento de Psicobiologia, Universidade Federal de Sao Paulo UNIFESP, Sao Paulo, Brazil
    Sleep Med 11:441-6. 2010
    ..To estimate the prevalence of Obstructive Sleep Apnea Syndrome (OSAS), using current clinical and epidemiological techniques, among the adult population of Sao Paulo, Brazil...
  9. ncbi The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation
    Hans P A Van Dongen
    Unit for Experimental Psychiatry, Division of Sleep and Chronobiology, Department of Psychiatry, and Centerfor Sleep and Respiratory Neurobiology, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
    Sleep 26:117-26. 2003
    ....
  10. ncbi Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure
    Takuya Yokoe
    First Department of Internal Medicine, Showa University, Tokyo, Japan
    Circulation 107:1129-34. 2003
    ..In the present study, we examined serum levels of CRP and IL-6, IL-6 production by monocytes, and the effect of nasal continuous positive airway pressure (nCPAP) in patients with obstructive sleep apnea syndrome (OSAS)...
  11. pmc Obstructive sleep apnea-hypopnea and incident stroke: the sleep heart health study
    Susan Redline
    Brigham and Women s Hospital, 221 Longwood Ave, Boston, MA 02115M, USA
    Am J Respir Crit Care Med 182:269-77. 2010
    ....
  12. pmc Association of sleep apnea and type II diabetes: a population-based study
    Kevin J Reichmuth
    Department of Medicine, University of Wisconsin Medical School, Madison, WI, USA
    Am J Respir Crit Care Med 172:1590-5. 2005
    ..Cross-sectional association has been reported between sleep-disordered breathing (SDB) and insulin resistance, but no prospective studies have been performed to determine whether SDB is causal in the development of diabetes...
  13. pmc Sleep apnea as an independent risk factor for all-cause mortality: the Busselton Health Study
    Nathaniel S Marshall
    Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia
    Sleep 31:1079-85. 2008
    ..However, it is unknown whether sleep apnea is an independent risk factor for all-cause mortality in a community-based sample free from clinical referral bias...
  14. ncbi Upper airway obstructive disease in mucopolysaccharidoses: polysomnography, computed tomography and nasal endoscopy findings
    F Santamaria
    Department of Pediatrics, Federico II University, Via Pansini 5, 80131, Naples, Italy
    J Inherit Metab Dis 30:743-9. 2007
    ..In a cross-sectional study over 2 years we evaluated upper airway obstructive disease through overnight polysomnography, upper airway computed tomography and nasal endoscopy in 5 children and 6 adults with mucopolysaccharidoses ..
  15. ncbi Obstructive sleep apnoea
    Atul Malhotra
    Brigham and Women s Hospital and Massachusetts General Hospital, Harvard Medical School, Boston, MA 02115, USA
    Lancet 360:237-45. 2002
    ..history (snoring, daytime sleepiness) and physical examination (increased neck circumference), but overnight polysomnography is needed to confirm presence of the disorder...
  16. ncbi Obstructive sleep apnea is independently associated with insulin resistance
    Mary S M Ip
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong S A R, PR China
    Am J Respir Crit Care Med 165:670-6. 2002
    ..A total of 270 consecutive subjects (197 male) who were referred for polysomnography and who did not have known diabetes mellitus were included, and 185 were documented to have OSA defined as an ..
  17. ncbi Overnight verbal memory retention correlates with the number of sleep spindles
    Z Clemens
    National Institute of Psychiatry and Neurology, Department of Neurology, H 1021 Budapest, Huvosvolgyi ut 116, Hungary
    Neuroscience 132:529-35. 2005
    ..The data strongly support theories suggesting a link between sleep spindle activity and verbal memory consolidation...
  18. pmc Cardiovascular morbidity in obstructive sleep apnea: oxidative stress, inflammation, and much more
    David Gozal
    Kosair Children s Hospital Research Institute, University of Louisville School of Medicine, 570 South Preston Street, Suite 204, Louisville, KY 40202, USA
    Am J Respir Crit Care Med 177:369-75. 2008
    ....
  19. pmc Clinical guidelines for the use of unattended portable monitors in the diagnosis of obstructive sleep apnea in adult patients. Portable Monitoring Task Force of the American Academy of Sleep Medicine
    Nancy A Collop
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    J Clin Sleep Med 3:737-47. 2007
    ..PM may be used as an alternative to polysomnography (PSG) for the diagnosis of OSA in patients with a high pretest probability of moderate to severe OSA...
  20. pmc Effects of suvorexant, an orexin receptor antagonist, on sleep parameters as measured by polysomnography in healthy men
    Hong Sun
    Merck Sharp Dohme Corp, Whitehouse Station, NJ, USA
    Sleep 36:259-67. 2013
    ..This report describes the effects of nighttime administration of suvorexant on polysomnography (PSG) sleep parameters in healthy young men.
  21. pmc Endothelial dysfunction in children without hypertension: potential contributions of obesity and obstructive sleep apnea
    Rakesh Bhattacharjee
    Department of Pediatrics, The University of Chicago, Chicago, IL 60637, USA
    Chest 141:682-91. 2012
    ..Endothelial dysfunction can develop in the context of both obesity and obstructive sleep apnea (OSA) in children. However, the potential interactions between OSA and obesity have not been defined...
  22. pmc Differences in craniofacial structures and obesity in Caucasian and Chinese patients with obstructive sleep apnea
    Richard W W Lee
    Centre for Sleep Health and Research, Department of Respiratory Medicine, Royal North Shore Hospital, NSW, Australia
    Sleep 33:1075-80. 2010
    ..To explore differences in craniofacial structures and obesity between Caucasian and Chinese patients with obstructive sleep apnea (OSA)...
  23. ncbi Practice parameters for the indications for polysomnography and related procedures: an update for 2005
    Clete A Kushida
    Stanford University Center of Excellence for Sleep Disorders, Stanford, CA, USA
    Sleep 28:499-521. 2005
    ..practice parameters are an update of the previously-published recommendations regarding the indications for polysomnography and related procedures in the diagnosis of sleep disorders...
  24. ncbi Day-night pattern of sudden death in obstructive sleep apnea
    Apoor S Gami
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
    N Engl J Med 352:1206-14. 2005
    ..m. Obstructive sleep apnea is highly prevalent and associated with neurohormonal and electrophysiological abnormalities that may increase the risk of sudden death from cardiac causes, especially during sleep...
  25. ncbi Sleep and Parkinson's disease: a review of case-control polysomnography studies
    Tasneem Peeraully
    National Neuroscience Institute, Department of Neurology, Singapore General Hospital, Singapore, Singapore
    Mov Disord 27:1729-37. 2012
    ..We performed a systematic review of case-control polysomnography studies to evaluate the relationship between PD and sleep disorders...
  26. ncbi The official World Association of Sleep Medicine (WASM) standards for recording and scoring periodic leg movements in sleep (PLMS) and wakefulness (PLMW) developed in collaboration with a task force from the International Restless Legs Syndrome Study Grou
    Marco Zucconi
    Sleep Disorders Center, San Raffaele Hospital, Milano, Italy
    Sleep Med 7:175-83. 2006
  27. ncbi Are spatial memories strengthened in the human hippocampus during slow wave sleep?
    Philippe Peigneux
    Cyclotron Research Center, University of Liege, B 4000 Liege, Belgium
    Neuron 44:535-45. 2004
    ....
  28. pmc Quantifying the risk of neurodegenerative disease in idiopathic REM sleep behavior disorder
    R B Postuma
    Department of Neurology, L7 305 Montreal General Hospital, 1650 Cedar Ave, Montreal, Quebec, Canada
    Neurology 72:1296-300. 2009
    ..Obtaining an accurate picture of this risk is essential for counseling patients and for development of potential neuroprotective therapies...
  29. ncbi STOP questionnaire: a tool to screen patients for obstructive sleep apnea
    Frances Chung
    Department of Psychiatry, University of Toronto, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
    Anesthesiology 108:812-21. 2008
    ..However, no screening tool for OSA has been validated in surgical patients. This study was conducted to develop and validate a concise and easy-to-use questionnaire for OSA screening in surgical patients...
  30. ncbi Dysfunction of arousal systems in sleep-related migraine without aura
    G Della Marca
    Department of Neuroscience, Catholic University Rome, Italy
    Cephalalgia 26:857-64. 2006
    ..The reduced arousal index in REM suggests a dysfunction in neural structures involved in both the control of REM sleep and the pathophysiology of migraine, such as the hypothalamus and the brainstem...
  31. ncbi Sleep spindles and learning potential
    S M Fogel
    Department of Psychology, Trent University, Peterborough, ON, Canada
    Behav Neurosci 121:1-10. 2007
    ..A similar pattern was observed between spindles and PIQ. It was hypothesized that high-IQ individuals have more spindles that can support more complex cortical networks underlying perceptual/analytical abilities...
  32. ncbi Hippocampal area metabolites relate to severity and cognitive function in obstructive sleep apnea
    Delwyn J Bartlett
    Woolcock Institute of Medical Research, University of Sydney, Sydney, NSW, Australia
    Sleep Med 5:593-6. 2004
    ..As the hippocampus is particularly susceptible to hypoxia, we hypothesized that it may show biochemical abnormalities, and they may relate to apnea severity...
  33. ncbi Antioxidant status in patients with sleep apnoea and impact of continuous positive airway pressure treatment
    A Barcelo
    Serveis de Analisis Cliniques, and Pneumologia, Hospital Universitario Arnau de Vilanova, Lleida, Spain
    Eur Respir J 27:756-60. 2006
    ..In conclusion, the results indicate that patients with obstructive sleep apnoea syndrome have a decreased antioxidant capacity that is partially reversed by continuous positive airway pressure treatment...
  34. ncbi The effects of sleep deprivation on pain inhibition and spontaneous pain in women
    Michael T Smith
    Behavioral Sleep Medicine Program, Johns Hopkins Bayview, Johns Hopkins University School of Medicine, Baltimore MD 21287, USA
    Sleep 30:494-505. 2007
    ....
  35. pmc Declarative memory consolidation: mechanisms acting during human sleep
    Steffen Gais
    Department of Neuroendocrinology, University of Lubeck, Lubeck 23538, Germany
    Learn Mem 11:679-85. 2004
    ..In addition, sleep seems to provide an optimal milieu for declarative memory reprocessing and consolidation by reducing cholinergic activation and the cortisol feedback to the hippocampus during SWS...
  36. pmc Case control polysomnographic studies of sleep disorders in Parkinson's disease
    Ming Hui Yong
    Department of Neurology, National Neuroscience Institute, Singapore
    PLoS ONE 6:e22511. 2011
    ..The relationship between a number of primary sleep disorders and Parkinson's disease (PD) is still debated. There are limited case control polysomnographic studies in PD and most of these study sample sizes are small...
  37. pmc Endothelial progenitor cells and vascular dysfunction in children with obstructive sleep apnea
    Leila Kheirandish-Gozal
    Section of Pediatric Sleep Medicine, Department of Pediatrics, The University of Chicago, 5721 S Maryland Avenue, MC 8000, Suite K 160, Chicago, IL 60637, USA
    Am J Respir Crit Care Med 182:92-7. 2010
    ..Endothelial dysfunction is a potential complication of obstructive sleep apnea syndrome (OSAS) in children ascribed to systemic inflammatory changes. However, not all children with OSAS will manifest endothelial dysfunction...
  38. ncbi Predicting sleep apnea and excessive day sleepiness in the severely obese: indicators for polysomnography
    John B Dixon
    Monash University Department of Surgery, Alfred Hospital, Melbourne, Australia
    Chest 123:1134-41. 2003
    Obstructive sleep apnea (OSA) is common in severely obese subjects (body mass index [BMI] > 35). Overnight polysomnography (OPS) is the "gold standard" method of evaluating this condition; however, it is time-consuming, inconvenient, ..
  39. ncbi Sleep and sleep-disordered breathing in adults with predominantly mild obstructive airway disease
    Mark H Sanders
    Division of Pulmonary, Allergy, and Critical Care Medicine, Montefiore University Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Am J Respir Crit Care Med 167:7-14. 2003
    ..b>Polysomnography and spirometry results from 5,954 participants in the Sleep Heart Health Study were analyzed...
  40. ncbi Sleep disorders in patients with traumatic brain injury: a review
    Richard J Castriotta
    Division of Pulmonary, Critical Care and Sleep Medicine, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    CNS Drugs 25:175-85. 2011
    ..Approximately 46% of all chronic TBI patients have sleep disorders, which require nocturnal polysomnography and the Multiple Sleep Latency Test for diagnosis...
  41. ncbi Effect of nasal continuous positive airway pressure treatment on blood pressure in patients with obstructive sleep apnea
    Heinrich F Becker
    Department of Respiratory Medicine, Philipps University Marburg, Marburg, Germany
    Circulation 107:68-73. 2003
    ..Therefore, we studied the effect of nCPAP on arterial hypertension in patients with OSA...
  42. ncbi Acceptance and long-term compliance of nCPAP in obstructive sleep apnea
    Wietske Richard
    Department of Otolaryngology Head and Neck Surgery, St Lucas Andreas Hospital, Amsterdam, The Netherlands
    Eur Arch Otorhinolaryngol 264:1081-6. 2007
    ..Questionnaires were sent to 256 patients, who were referred to our clinic for an overnight polysomnography from January 1997 to July 2005 and received nCPAP therapy for OSAS...
  43. ncbi Effects of partial circadian adjustments on sleep and vigilance quality during simulated night work
    Simon Chapdelaine
    Chronobiology Laboratory, Center for Advanced Research in Sleep Medicine, Sacré Coeur Hospital of Montréal, Montreal, QC, Canada
    J Sleep Res 21:380-9. 2012
    ..These strategies need to be tested in the field, to determine whether they can be adapted to real-life situations and provide effective support to night workers...
  44. ncbi Fatigue and sleep disturbance following traumatic brain injury--their nature, causes, and potential treatments
    Jennie L Ponsford
    School of Psychology and Psychiatry, Monash University, Victoria, Australia
    J Head Trauma Rehabil 27:224-33. 2012
    ..Although fatigue and sleep disturbance are commonly reported following traumatic brain injury (TBI), understanding of their nature and treatment remains limited...
  45. ncbi Objective measurements of sleep for non-laboratory settings as alternatives to polysomnography--a systematic review
    Alexander T M van de Water
    Utrecht University, General Health Sciences, Physiotherapy Science, Utrecht, The Netherlands
    J Sleep Res 20:183-200. 2011
    ..Laboratory-based polysomnography (PSG) is deemed the gold standard to measure sleep objectively, but is impractical for long-term and home ..
  46. ncbi An E-health solution for automatic sleep classification according to Rechtschaffen and Kales: validation study of the Somnolyzer 24 x 7 utilizing the Siesta database
    Peter Anderer
    Department of Psychiatry, Medical University of Vienna, Vienna, Austria
    Neuropsychobiology 51:115-33. 2005
    ..5% of the recordings) are changed, can definitely be neglected. Thus, the validation study proved the high reliability and validity of the Somnolyzer 24 x 7 and demonstrated its applicability in clinical routine and sleep studies...
  47. pmc Activation of the prostaglandin system in response to sleep loss in healthy humans: potential mediator of increased spontaneous pain
    Monika Haack
    Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Pain 145:136-41. 2009
    ..Activation of the PGE2 system appears to be a potential mediator of increased spontaneous pain in response to insufficient sleep...
  48. ncbi Practice parameters for the treatment of snoring and Obstructive Sleep Apnea with oral appliances: an update for 2005
    Clete A Kushida
    Stanford University Center of Excellence for Sleep Disorders, CA, USA
    Sleep 29:240-3. 2006
    ..Follow-up polysomnography or an attended cardiorespiratory (Type 3) sleep study is needed to verify efficacy, and may be needed when ..
  49. ncbi Sleep disturbances in Malaysian patients with Parkinson's disease using polysomnography and PDSS
    M I Norlinah
    Neurology Unit, Department of Medicine, Universiti Kebangsaan Malaysia Medical Center, Kuala Lumpur, Malaysia
    Parkinsonism Relat Disord 15:670-4. 2009
    ..However, studies in the Asian population are limited...
  50. ncbi Continuous positive airway pressure therapy improves vascular dysfunction and decreases oxidative stress in patients with the metabolic syndrome and obstructive sleep apnea syndrome
    Jun ichi Oyama
    Department of Cardiovascular, Respiratory, and Geriatric Medicine, Kyushu University Hospital at Beppu and Medical Institute of Bioregulation, Kyushu University, Oita, Japan
    Clin Cardiol 35:231-6. 2012
    ..Therefore, nasal continuous positive airway pressure (CPAP) therapy may have beneficial effects in patients with the MetS and OSAS...
  51. ncbi One hundred consecutive patients undergoing drug-induced sleep endoscopy: results and evaluation
    Madeline J L Ravesloot
    Department of Otolaryngology Head and Neck Surgery, Sint Lucas Andreas Ziekenhuis, Amsterdam, The Netherlands
    Laryngoscope 121:2710-6. 2011
    b>Polysomnography (PSG) is mandatory in the diagnostic workup of obstructive sleep apnea (OSA); drug-induced sleep endoscopy (DISE) is a valid addition...
  52. pmc Validation of the ApneaLink for the screening of sleep apnea: a novel and simple single-channel recording device
    Milton K Erman
    Pacific Sleep Medicine Services, San Diego, CA, USA
    J Clin Sleep Med 3:387-92. 2007
    ..The purpose of the study was to validate the ApneaLink device (ResMed Corporation, Poway, Calif) for use as a screening tool for sleep apnea in clinical practice...
  53. ncbi Investigation of sleep disturbance in chronic low back pain: an age- and gender-matched case-control study over a 7-night period
    Alexander T M van de Water
    School of Public Health, Physiotherapy and Population Science, Health Sciences Centre, University College Dublin, Dublin 4, Ireland
    Man Ther 16:550-6. 2011
    ..05). The findings provide some evidence to support self-reported sleep assessment as an outcome measure in CLBP research, while further research is needed to determine the validity of objective sleep measurement in this population...
  54. ncbi Validation of a portable recording device (ApneaLink) for identifying patients with suspected obstructive sleep apnoea syndrome
    S S S Ng
    Department of Medicine and Therapeutics, Division of Respiratory Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China
    Intern Med J 39:757-62. 2009
    b>Polysomnography (PSG) is currently the standard diagnostic procedure for sleep apnoea...
  55. ncbi Relation of sleep-disordered breathing to cardiovascular disease risk factors: the Sleep Heart Health Study
    A B Newman
    University of Pittsburgh, 3520 Fifth Avenue, Suite 300, Pittsburgh, PA 15213, USA
    Am J Epidemiol 154:50-9. 2001
    ..6,440 men and women over age 40 years conducted from October 1995 to February 1998 and characterized by home polysomnography. In 4,991 participants who were free of self-reported CVD at the time of the sleep study, moderate levels of ..
  56. ncbi Inflammatory proteins in patients with obstructive sleep apnea with and without daytime sleepiness
    Mónica de la Peña Bravo
    Hospital Universitario Son Dureta, Servicio de Neumologia, Palma de Mallorca, Baleares 07014, Spain
    Sleep Breath 11:177-85. 2007
    ..A total of 50 consecutive patients with OSAS undergoing overnight polysomnography with or without EDS and 20 controls were evaluated...
  57. ncbi Current opinions and clinical practice in the titration of oral appliances in the treatment of sleep-disordered breathing
    Marijke Dieltjens
    Clinical Department of Special Care Dentistry, University of Antwerp UA and Antwerp University Hospital UZA, Edegem, Antwerp, Belgium
    Sleep Med Rev 16:177-85. 2012
    ..At present, a consensus exists that an optimal titration protocol is of primary importance to achieve a successful treatment outcome with an MRA. To date however, there is no consensus on how to define the optimal titration protocol...
  58. ncbi Validation of an automated wireless system to monitor sleep in healthy adults
    John R Shambroom
    Zeo Sleep Research Center, Zeo, Inc, Newton, MA, USA
    J Sleep Res 21:221-30. 2012
    ..Twenty-nine healthy adults underwent concurrent sleep measurement via the WS, polysomnography (PSG) and an actigraph (ACT) in a sleep laboratory for one assessment night preceded by an acclimation night...
  59. pmc Objective and subjective assessment of sleep in chronic low back pain patients compared with healthy age and gender matched controls: a pilot study
    Grainne M O'Donoghue
    School of Physiotherapy and Performance Science, Health Sciences, University College Dublin, Belfield, Dublin 4, Ireland
    BMC Musculoskelet Disord 10:122. 2009
    ....
  60. ncbi Risk for Obstructive Sleep Apnea by Berlin Questionnaire, but not daytime sleepiness, is associated with resistant hypertension: a case-control study
    Miguel Gus
    Division of Cardiology, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
    Am J Hypertens 21:832-5. 2008
    Obstructive Sleep Apnea Syndrome (OSAS) is a risk factor for resistant hypertension. Overnight polysomnography and portable sleep monitors are not generally available and questionnaires may be useful for screening OSAS...
  61. ncbi The association of oxidative stress with central obesity in obstructive sleep apnea
    Sang Don Lee
    Department of Neuropsychiatry, Seoul National University Bundang Hospital, 166 Gumi ro, Bundang gu, Seongnam si, Gyeonggi Do, 463 707, South Korea
    Sleep Breath 16:511-7. 2012
    ..The purpose of this paper is to evaluate concentrations of multiple oxidative stress and antioxidant status markers in patients with obstructive sleep apnea (OSA) and normal controls of comparable obesity...
  62. ncbi High altitude sleep disturbances monitored by actigraphy and polysomnography
    Yvonne Nussbaumer-Ochsner
    Pulmonary Division and Sleep Disorders Center, University Hospital of Zurich, and Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland
    High Alt Med Biol 12:229-36. 2011
    Data on sleep at altitude are scant due to the limited availability of polysomnography. Therefore, we investigated whether actigraphy might serve as a simple tool for monitoring sleep during altitude field studies.
  63. ncbi Sleep disorders and fibromyalgia
    Suely Roizenblatt
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Avenida Angélica 1996, Andar 1, São Paulo 01228 200, Brazil
    Curr Pain Headache Rep 15:347-57. 2011
    ..Even though sleep recording is not part of the routine evaluation, polysomnography may disclose primary sleep disorders in patients with fibromyalgia, including obstructive sleep apnea and ..
  64. pmc Polysomnographic findings are associated with cephalometric measurements in mouth-breathing children
    Maria Ligia Juliano
    Neuro Sono Section, Department of Neurology, Universidade ederal de São Paulo, Brazil
    J Clin Sleep Med 5:554-61. 2009
    ..The aim of this study was to determine whether an association exists between polysomnographic findings and cephalometric measures in mouth-breathing children...
  65. pmc Brain activation changes before and after PAP treatment in obstructive sleep apnea
    Vincenza Castronovo
    Sleep Disorders Center, Vita Salute San Raffaele University, Milan, Italy
    Sleep 32:1161-72. 2009
    ....
  66. ncbi Oxidative and carbonyl stress in patients with obstructive sleep apnea treated with continuous positive airway pressure
    Peter Celec
    Institute of Molecular Biomedicine, Comenius University, Sasinkova 4, 811 08, Bratislava, Slovakia
    Sleep Breath 16:393-8. 2012
    ..Continuous positive airway pressure (CPAP) improves symptoms and prognosis of patients with OSAS...
  67. ncbi Objective evidence that bariatric surgery improves obesity-related obstructive sleep apnea
    Krista L Haines
    Department of Surgery, Interdisciplinary Obesity Group, University of South Florida, Health Sciences Center, Tampa, FL 33601, USA
    Surgery 141:354-8. 2007
    ..Obstructive sleep apnea (OSA) is associated with obesity. Our aim in this study is to report objective improvement of obesity-related OSA and sleep quality after bariatric surgery...
  68. pmc Sleep disordered breathing and metabolic syndrome
    F Javier Nieto
    Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, 707C WARF Office Building, 610 Walnut St, Madison, WI 53726, USA
    WMJ 108:263-5. 2009
    ..This article examines the association between SDB and the prevalence of metabolic syndrome (MS) in a community-based sample...
  69. ncbi Effects of obstructive sleep apnea on cognitive function: a comparison between younger and older OSAS patients
    A Mathieu
    Centre d Etude du Sommeil et des Rythmes Biologiques, Hopital du Sacre Coeur de Montreal, 5400 Boul Gouin Ouest, Montreal, Que, Canada H4J 1C5
    Sleep Med 9:112-20. 2008
    ..The aim of the study was to assess the effects of age on cognitive functions in OSAS patients. It was hypothesized that older OSAS patients will exhibit significant cognitive dysfunction relative to younger OSAS patients and controls...
  70. ncbi Sleep and memory in healthy children and adolescents - a critical review
    Marta Kopasz
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Hauptstrasse 5, 79104 Freiburg, Germany
    Sleep Med Rev 14:167-77. 2010
    ..This line of research can provide valuable input relevant to teaching, learning and public health policy...
  71. ncbi UPPP combined with radiofrequency thermotherapy of the tongue base for the treatment of obstructive sleep apnea syndrome
    Emke van den Broek
    Department of Otorhinolaryngology, Head and Neck Surgery, St Lucas Andreas Hospital, Jan Tooropstraat 164, 1061 AE, Amsterdam, The Netherlands
    Eur Arch Otorhinolaryngol 265:1361-5. 2008
    ..Adding RFTB to UPPP results in a mild improvement compared to UPPP alone. Although the addition of RFTB to UPPP seems to result in only a limited improvement, there is no major downside to it. RFTB is well tolerated and safe...
  72. ncbi Effect of uvulopalatopharyngoplasty on positional dependency in obstructive sleep apnea
    Chul Hee Lee
    Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 300 Goomi Dong, Bundang gu, Seongnam, Gyunggi do 463 707, South Korea
    Arch Otolaryngol Head Neck Surg 137:675-9. 2011
    ..To assess the effect of uvulopalatopharyngoplasty (UPPP) on positional dependency in patients with obstructive sleep apnea (OSA)...
  73. ncbi Fast and slow spindle involvement in the consolidation of a new motor sequence
    M Barakat
    Unité de Neuroimagerie Fonctionnelle, Centre de recherche de l Institut universitaire de geriatrie de Montreal, Montreal, QC, Canada
    Behav Brain Res 217:117-21. 2011
    ..Together, these results suggest that fast sleep spindles help activate the cerebral network involved in overnight MSL consolidation, while slow spindles do not appear to play a role in this mnemonic process...
  74. pmc The Insomnia Severity Index: psychometric indicators to detect insomnia cases and evaluate treatment response
    Charles M Morin
    Université Laval and Centre de recherche Université Laval Robert Giffard, Quebec, Canada
    Sleep 34:601-8. 2011
    ..This study examined psychometric indices of the Insomnia Severity Index (ISI) to detect cases of insomnia in a population-based sample and to evaluate treatment response in a clinical sample...
  75. ncbi The Sleep Heart Health Study: design, rationale, and methods
    S F Quan
    Department of Medicine and Respiratory Sciences Center, University of Arizona, Tucson 85724, USA
    Sleep 20:1077-85. 1997
    ..The study provides sufficient statistical power for assessing OSA and other SDB as risk factors for major cardiovascular events, including myocardial infarction and stroke...
  76. ncbi Comparison of cognitive performance among different age groups in patients with obstructive sleep apnea
    Manos Alchanatis
    Department of Pulmonary Medicine, University of Athens Medical School, Sotiria Hospital for Chest Diseases, Greece
    Sleep Breath 12:17-24. 2008
    ..Patients and controls were examined with all-night polysomnography and subsequently underwent cognitive testing via attention-alertness tests...
  77. ncbi Sao Paulo Epidemiologic Sleep Study: rationale, design, sampling, and procedures
    Rogério Santos-Silva
    Discipline of Medicine and Biology of Sleep, Department of Psychobiology, Univ Fed Sao Paulo UNIFESP, Rua Napoleao de Barros 925, 1o andar, CEP 04024 002, Sao Paulo SP, Brazil
    Sleep Med 10:679-85. 2009
    ....
  78. ncbi Cyclic alternating pattern (CAP): the marker of sleep instability
    Liborio Parrino
    Sleep Disorders Center, Department of Neurosciences, University of Parma, Italy
    Sleep Med Rev 16:27-45. 2012
    ....
  79. ncbi Reliability and validity of a Norwegian version of the Epworth sleepiness scale
    Kornelia K Beiske
    Department of Neurology, Medical Divison, Akershus University Hospital, Lørenskog, Norway
    Sleep Breath 13:65-72. 2009
    ..The objective of this study was to assess the reliability and validity of a Norwegian version of the self-administered Epworth sleepiness scale (ESS)...
  80. ncbi Description and validation of the apnea risk evaluation system: a novel method to diagnose sleep apnea-hypopnea in the home
    Philip R Westbrook
    Advanced Brain Monitoring, Inc, 2850 Pio Pico Dr, Suite A, Carlsbad, CA 92008, USA
    Chest 128:2166-75. 2005
    ..To evaluate the accuracy and practicality of the Apnea Risk Evaluation System (ARES; Advanced Brain Monitoring; Carlsbad, CA), a limited-channel system for diagnosing sleep apnea/hypopnea in the home...
  81. ncbi Neurobehavioral implications of habitual snoring in children
    Louise M O'Brien
    Kosair Children s Hospital Research Institute and Division of Pediatric Sleep Medicine, Department of Pediatrics, University of Louisville, Louisville, Kentucky 40202, USA
    Pediatrics 114:44-9. 2004
    ..However, PS has not been well evaluated, and it is unknown whether PS is associated with serious morbidity. This study investigated whether PS is associated with neurobehavioral deficits in children...
  82. ncbi Long-term effects of nasal continuous positive airway pressure therapy on cardiovascular outcomes in sleep apnea syndrome
    Liam S Doherty
    Respiratory Sleep Disorders Unit, St Vincent s University Hospital, Elm Park, Dublin 4, Ireland
    Chest 127:2076-84. 2005
    ..Obstructive sleep apnea syndrome (OSAS) has been associated with increased morbidity and mortality, principally from cardiovascular disease, but the impact of nasal continuous positive airway pressure (CPAP) therapy is unclear...
  83. ncbi Sleep in children improves memory performance on declarative but not procedural tasks
    Ines Wilhelm
    Department of Neuroendocrinology, University of Lubeck, Lubeck 23538, Germany
    Learn Mem 15:373-7. 2008
    ..However, opposite to adults, children showed smaller improvement in finger-tapping skill across retention sleep than wakefulness, indicating that sleep-dependent procedural memory consolidation depends on developmental stage...
  84. ncbi Sleep restriction over several days does not affect long-term recall of declarative and procedural memories in adolescents
    Ulrich Voderholzer
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Germany
    Sleep Med 12:170-8. 2011
    ..The current study addressed the question whether different extents of sleep restriction after learning would impair long-term memory consolidation in adolescents...
  85. ncbi Dreamed movement elicits activation in the sensorimotor cortex
    Martin Dresler
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Curr Biol 21:1833-7. 2011
    ..By combining brain imaging with polysomnography and exploiting the state of "lucid dreaming," we show here that a predefined motor task performed during ..
  86. pmc Decision making in narcolepsy with cataplexy
    Sophie Bayard
    Service de Neurologie, Unite des troubles du sommeil, Hôpital Gui de Chauliac Montpellier, France
    Sleep 34:99-104. 2011
    ..The hypocretin system plays a crucial role in sleep, wakefulness, and energy homeostasis, and is also involved in emotion regulation, reward processing, and addiction...
  87. ncbi Effects of caffeine on daytime recovery sleep: A double challenge to the sleep-wake cycle in aging
    Julie Carrier
    Centre d Etude du Sommeil et des Rythmes Biologiques, Hopital du Sacre Coeur de Montreal, Que, Canada
    Sleep Med 10:1016-24. 2009
    ..This study compares the effects of caffeine on daytime recovery sleep in young (20-30 y.) and middle-aged subjects (45-60 y.)...
  88. pmc Association study of serotonin transporter gene polymorphisms with obstructive sleep apnea syndrome in Chinese Han population
    Weihua Yue
    Mental Health Institute, The Second Xiangya Hospital, Central South University, Changsha, PR China
    Sleep 31:1535-41. 2008
    ....
  89. pmc Large-scale microelectrode recordings of high-frequency gamma oscillations in human cortex during sleep
    Michel Le Van Quyen
    Centre de Recherche de l Institut du Cerveau et de la Moelle Epinière INSERM Unité Mixte de Recherche en Santé 975 Centre National de la Recherche Scientifique Unité Mixte de Recherche 7225, Hopital de la Pitie Salpetriere, Paris, France
    J Neurosci 30:7770-82. 2010
    ..We speculate that these high-frequency patterns briefly restore "microwake" activity and are important for consolidation of memory traces acquired during previous awake periods...
  90. ncbi Is obstructive sleep apnea a problem in Parkinson's disease?
    Valerie Cochen De Cock
    Sleep Disorders Unit, Pitie Salpetriere Hospital, APHP, Paris, France
    Sleep Med 11:247-52. 2010
    ..Upper airway dysfunction in PD may promote obstructive sleep apnea. However, the frequency and clinical relevance of sleep-disordered breathing in PD remains unclear...
  91. ncbi Effects of moderate-intensity exercise on polysomnographic and subjective sleep quality in older adults with mild to moderate sleep complaints
    Abby C King
    Department of Health Research and Policy, Stanford Prevention Research Center, Stanford University School of Medicine, SPRC, 211 Quarry Rd, Room N229, Stanford, CA 94305 5705, USA
    J Gerontol A Biol Sci Med Sci 63:997-1004. 2008
    ..This study sought to determine the 12-month effects of exercise increases on objective and subjective sleep quality in initially inactive older persons with mild to moderate sleep complaints...
  92. pmc Cognitive behavioral therapy for patients with primary insomnia or insomnia associated predominantly with mixed psychiatric disorders: a randomized clinical trial
    Jack D Edinger
    Psychology Service, VA Medical Center Durham, NC 27705, USA
    Sleep 32:499-510. 2009
    ..This study was conducted to evaluate the efficacy of cognitive behavioral therapy (CBT) against a sleep hygiene education control therapy in patients with primary or comorbid insomnia...
  93. ncbi The Berlin questionnaire for sleep apnea in a sleep clinic population: relationship to polysomnographic measurement of respiratory disturbance
    Negar Ahmadi
    Department of Psychiatry, Toronto Western Hospital, ON, Canada
    Sleep Breath 12:39-45. 2008
    ..5%) as being at high-risk of having sleep apnea, but overnight polysomnography found only 34 of the 130 patients (26.2%) had an RDI > 10. The BQ performed with 0.62 sensitivity and 0...
  94. ncbi Polysomnographic diagnosis of idiopathic REM sleep behavior disorder
    Jacques Montplaisir
    Centre d Etude du Sommeil et des Rythmes Biologiques, Hopital du Sacre Coeur de Montreal, Quebec, Canada
    Mov Disord 25:2044-51. 2010
    ..For the five RBD patients who did not show chin EMG abnormalities, it cannot be excluded that they had increased phasic EMG activity in the upper limbs and presented visible motor activity...
  95. ncbi Obstructive sleep apnoea and urine catecholamines in hypertensive males: a population-based study
    A Elmasry
    Dept of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Akademiska sjukhuset, Sweden
    Eur Respir J 19:511-7. 2002
    ..Elevated sympathoadrenal activity may explain the increased cardiovascular morbidity associated with obstructive sleep apnoea...
  96. ncbi Cost-effectiveness of split-night polysomnography and home studies in the evaluation of obstructive sleep apnea syndrome
    Peter A Deutsch
    Department of Economics, Williams College, Williamstown, MA, USA
    J Clin Sleep Med 2:145-53. 2006
    Split-night polysomnography (PSG) and unattended home sleep studies have come into use as less-expensive tests for obstructive sleep apnea syndrome, but their impact on cost-effectiveness of the overall evaluation and treatment is ..
  97. ncbi Oral appliance therapy reduces blood pressure in obstructive sleep apnea: a randomized, controlled trial
    Helen Gotsopoulos
    Department of Respiratory and Sleep Medicine, St George Hospital, The University of New South Wales, Sydney Australia
    Sleep 27:934-41. 2004
    ..To investigate the short-term effect (4 weeks) of oral appliance therapy for obstructive sleep apnea on blood pressure...
  98. ncbi Polysomnography performed in the unattended home versus the attended laboratory setting--Sleep Heart Health Study methodology
    Conrad Iber
    Department of Medicine, University of Minnesota, Minneapolis, MN, USA
    Sleep 27:536-40. 2004
    ..To compare polysomnographic recordings obtained in the home and laboratory setting...
  99. pmc Endothelial dysfunction in obese non-hypertensive children without evidence of sleep disordered breathing
    Rakesh Bhattacharjee
    Division of Pediatric Sleep Medicine, Department of Pediatrics, University of Louisville, Kentucky, USA
    BMC Pediatr 10:8. 2010
    ..It is unknown whether obesity causes endothelial dysfunction in children in the absence of OSAS. This study examines endothelial function in obese and non-obese children without OSAS...
  100. ncbi A single night of partial sleep deprivation induces insulin resistance in multiple metabolic pathways in healthy subjects
    Esther Donga
    Department of Endocrinology and Metabolic Diseases, C4 R, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
    J Clin Endocrinol Metab 95:2963-8. 2010
    ..Subsequent nights with partial sleep restriction result in impaired glucose tolerance, but the effects on insulin sensitivity have not been characterized...
  101. ncbi Clinical effects of sleep fragmentation versus sleep deprivation
    Michael H Bonnet
    Dayton Department of Veterans Affairs Medical Center, Wright State University, Kettering Medical Center, Dayton, OH 45428, USA
    Sleep Med Rev 7:297-310. 2003
    ....

Research Grants73

  1. Polysomnography in Homeopathic Remedy Effects
    Iris Bell; Fiscal Year: 2007
    ..This study will contribute to our long-range goal of understanding the neurophysiological and biopsychosocial mechanisms of classical homeopathic remedy treatment in patients with specific clinical conditions. ..
  2. Validation of Apnea Risk Evaluation System Sleep Scoring
    DANIEL LEVENDOWSKI; Fiscal Year: 2007
    ..The gold standard for the diagnosis of OSA is attended, overnight laboratory polysomnography (PSG). Advanced Brain Monitoring, Inc...
  3. Autonomic, Endothelial, and Inflammatory Correlates of Sleep Duration
    MERCEDES RENEE CARNETHON; Fiscal Year: 2012
    ..IL area who do not have SDB as determined by validated screening questionnaires and in-home overnight polysomnography. Half of the population will be female and 25% each will be of Caucasian, African- American, Asian, and ..
  4. Cerebral metabolism, EEG, and sleep cycling in critically ill neonates
    Renée A Shellhaas; Fiscal Year: 2013
    ..Sleep Disorders Center and will oversee the PI's training in the theory, practice, and interpretation of polysomnography, and provide assistance with protocol development and implementation, along with guidance on transition to ..
  5. Evaluation of obstructive sleep apnea with long range 3D endoscopic FDOCT
    Jun Zhang; Fiscal Year: 2013
    ..The current gold standard diagnostic modality, overnight polysomnography is inconvenient, unable to provide information on upper airway structure and anatomy, and cannot identify the ..
  6. The Impact of Sleep-Disordered Breathing on Adverse Pregnancy Outcomes
    LOUISE M O apos BRIEN; Fiscal Year: 2010
    ..proof-of-concept" that habitual snoring is associated with objective measures of respiratory events from polysomnography in a sample of pregnant women...
  7. Sleep in Rats: From Conceptualization to Measurement, Analysis and Interpretation
    Gayle Giboney Page; Fiscal Year: 2010
    ..The key elements of this plan are to complete a foundational polysomnography course, and develop a working knowledge of the sleep literature relevant to my long-term research goal...
  8. Sleep Disordered Breathing and Passive Limb Movement in Children with Paraplegia
    Marlyn Woo; Fiscal Year: 2013
    ..Using a one-group, quasi-experimental, pre- and post- test design, we will perform overnight polysomnography on 26 pediatric and young adults with complete thoracic spinal cord injury (ASIA A paraplegia, age 12-25 ..
  9. Effects of sleep duration and architecture on insulin sensitivity
    MADHU NAGARAJU RAO; Fiscal Year: 2013
    ..clinical trial, we will assess: (1) the association between sleep architecture (sleep stages determined by polysomnography) and insulin sensitivity and (2) the specific sites of insulin resistance (ie, liver vs. skeletal muscle)...
  10. An RCT of telemedicine interventions for OSA
    DAVID W SPARROW; Fiscal Year: 2013
    ..Outcomes include the AHI derived from polysomnography, Epworth Sleepiness Scale score, Functional Outcomes of Sleep Questionnaire, BMI, physical activity, ..
  11. Circadian rhythm genes and sleep disturbances in the elderly
    Gregory J Tranah; Fiscal Year: 2010
    ..and African American participants (all with available DNA) completed wrist actigraphy and in-home overnight polysomnography. We are also including all African Americans with available DNA to improve our power to detect genotype ..
  12. Insomnia and Sleep Disordered Breathing in Seniors: A Longitudinal Outcome Study
    Nalaka S Gooneratne; Fiscal Year: 2010
    ..One major limitation of the current literature, however, is that objective measures of sleep derived by polysomnography have not been incorporated into large studies of insomnia outcomes in part because insomnia is largely a ..
  13. Melatonin in Menopausal Depression
    Barbara L Parry; Fiscal Year: 2012
    ..24-hour cycles of plasma melatonin (30 minute sampling in dim light), illumination, sleep and activity (by polysomnography and Actillume), as well as reproductive endocrine function (by gonadotropin and steroid levels) and BMI, in ..
  14. Influence of the Enteric Microbiome on the Genesis of Bronchopulmonary Dysplasia
    Aaron Hamvas; Fiscal Year: 2013
    ..In this single center project, limited polysomnography and echocardiography will be used to non- invasively and longitudinally assess airspace and pulmonary ..
  15. Impact of Sleep in the Restoring Insulin Secretion (RISE) Study
    Babak Mokhlesi; Fiscal Year: 2013
    ..to randomization, participants will undergo one week of home wrist actigraphy and one night of in-laboratory polysomnography (PSG)...
  16. Randomized Controlled Study of Adenotonsillectomy for Childhood Sleep Apnea
    SUSAN S REDLINE; Fiscal Year: 2010
    ..At baseline and 7 months later, we will obtain standardized overnight polysomnography, morning and evening blood pressures, anthropometry, a fasting blood sample, and perform a comprehensive ..
  17. Sleep Disruption and Mild Cognitive Impairment in Veterans
    CYNTHIA HOLDEN PHELAN; Fiscal Year: 2013
    ..2006;Saykin &Wishart, 2003). Electrophysiologic measurements during sleep (such as polysomnography and high-density EEG) provide a unique modality for investigating brain function as they minimize many ..
  18. Long-term effects of caffeine therapy for apnea of prematurity on sleep disorders
    Carole L Marcus; Fiscal Year: 2012
    ..Specifically, we will use ambulatory polysomnography to characterize breathing during sleep in ex-premature 5-6 year old children who received either caffeine or ..
  19. Pathogenesis of Sleep Disordered Breathing in Spinal Cord Injury Patients
    ABDUL SANKRI-TARBICHI; Fiscal Year: 2013
    ..To characterize the sleep and breathing state of each subject, polysomnography and upper airway collapsibility will be measured at baseline...
  20. Impaired Sleep, Insulin Action, and Overweight in Youth
    Tamara S Hannon; Fiscal Year: 2010
    ..Methods include hyperinsulinemic-euglycemic and hyperglycemic clamp tests, oral glucose tolerance testing, polysomnography (sleep study), body compostion evaluation, and cognitive function testing...
  21. Inflammation, Stress, and Social Behavior: Using Ecological Assessments and Model
    Charles Raison; Fiscal Year: 2012
    ..environments and will undergo TSST, 14 hour diurnal neuroendocrine and immune measurement and overnight sleep polysomnography in the Atlanta Clinical and Translational Science Institute Clinical Interactions Network site at Emory ..
  22. Sleep and Brain Structure in Heart Failure
    MARY ANN WOO; Fiscal Year: 2012
    ..mean diffusivity and fractional anisotropy) in HF depends on the presence of SDB (assessed via overnight polysomnography);2) show that nerve fibers (white matter - evaluated via structural MRI and fiber tracking techniques) ..
  23. Vulnerability to Major Depression and the Role of Sleep with Interferon-Alpha
    Francis E Lotrich; Fiscal Year: 2013
    ..We will test this hypothesis by using polysomnography and power spectral analysis to examine non-depressed people before they start IFN- a...
  24. Feasibility of Measuring Sleep in a Critical Care Environment
    Margaret A Pisani; Fiscal Year: 2010
    ..The goal of the study is to examine the feasibility of using portable polysomnography to study sleep in older patients admitted to a medical ICU who require mechanical ventilation...
  25. Use of PAP in women with pre-eclampsia
    LOUISE M O'BRIEN; Fiscal Year: 2013
    ..Therefore, the main goals of this research are to identify whether SDB - as measured by overnight polysomnography - is associated with pre-eclampsia, to confirm that use of auto-titrating positive airway pressure (auto-PAP) ..
  26. Impact of MTNR1B and CRY2 variants on sleep circadian physiology and metabolism
    Frank A Scheer; Fiscal Year: 2011
    ..metabolism phenotypic measurements, and include (1) a large cohort study (n=6400) in which questionnaire and polysomnography-based measures of sleep physiology (duration, quality, and architecture), estimates of circadian physiology (..
  27. Sleep-Related Determinants of Gestational Diabetes
    Bilgay Izci-Balserak; Fiscal Year: 2013
    ..In the K99 mentored phase, slow wave sleep changes will be determined using archival polysomnography data gathered from pregnant women in their first and third trimesters...
  28. Predictors and Targets of Response to Cytokine Antagonism in Depression
    Andrew H Miller; Fiscal Year: 2013
    ..not part of the original NIH study) including measures of multiple symptom domains, neurocognitive testing, polysomnography, and serial blood samples that can be assayed for kynurenine (KYN) pathway activation and diurnal ..
  29. Prospective Assessment of The Etiology of Insomnia in Middle Aged &Elder Adults
    MICHAEL LLOYD PERLIS; Fiscal Year: 2013
    ..The lab assessment will include two nights of polysomnography, the collection of urine samples at each void (to assess cortisol and melatonin levels), and the ..
  30. Unobtrusive measurement of sleep disordered breathing in the home
    Tamara Hayes; Fiscal Year: 2012
    ..The traditional gold standard for diagnosing and monitoring these disorders is overnight polysomnography (PSG). Unfortunately PSG is expensive, obtrusive, and inconvenient...
  31. Sleep in Cardiac patients with Implantable Cardioverter Defibrillators (ICD)
    CHRISTINA MCCRAE; Fiscal Year: 2009
    ..using a [3 stage] process to differentially diagnose sleep disorders in ICD patients: 1-clinical interview;2-polysomnography;3-sleep diaries...
  32. Sleep Apnea in TIA: Reducing Cardiovascular Risk with Positive Airway Pressure
    Henry Klar Yaggi; Fiscal Year: 2012
    ..will be randomly assigned to either usual care or a diagnosis and treatment approach that includes ambulatory polysomnography and initiation of autotitrating CPAP for sleep apnea in a 1:2 (control: intervention) randomization scheme...
  33. Predicting Obstructive Sleep Apnea in Down Syndrome
    BRIAN GARY SKOTKO; Fiscal Year: 2012
    ..Afterwards, all participants will undergo standardized polysomnography at the Children's Hospital Boston Sleep Laboratory where objective measurements will be collected on OSA...
  34. Developing Novel Methods to Elucidate Mechanisms of Pediatric Sleep Apnea
    Brian M McGinley; Fiscal Year: 2013
    ..These measurements, however, are laborious, and not well tolerated by young children or during REM sleep. Polysomnography is well tolerated by children, however, conventional measures of sleep apnea severity (AHI, arousal index, ..
  35. Asthma and Nocturnal Hypoxemia in Sickle Cell Anemia II
    Robert Strunk; Fiscal Year: 2013
    ..a unique cohort of 251 children with SCD, who have received both pulmonary function testing (PFT) and full polysomnography (PSG), the largest cohort of children with SCD with this extensive evaluation in the world...
  36. EPIDEMIOLOGY OF SLEEP-DISORDERED BREATHING IN ADULTS
    Paul E Peppard; Fiscal Year: 2013
    ..To achieve these goals, we will conduct follow-up protocols with overnight polysomnography, state of the art body habitus measures including DXA, echocardiography and vascular imaging, ..
  37. Passive Foot Movement and Sleep-Disordered Breathing in Heart Failure
    MARY ANN WOO; Fiscal Year: 2011
    ..40, dilated systolic dysfunction, not in acute HF, age 40-65 years) and SDB (AHI >5 via overnight polysomnography in the previous 6 months) who will be randomized to undergo passive foot movement either during the first or ..
  38. Sleep and Neurobehavioral Performance After Cleft Palate Repair
    LOUISE M O apos BRIEN; Fiscal Year: 2010
    ..All children will undergo nocturnal polysomnography followed by neuropsychological testing...
  39. ASSOCIATION OF SLEEP DISORDERS WITH CARDIOVASCULAR HEALTH ACROSS ETHNIC GROUPS
    SUSAN S REDLINE; Fiscal Year: 2013
    ..ancillary study to the Multi-Ethnic Study of Atherosclerosis (MESA), we aim to perform standardized in-home polysomnography and 7-day wrist actigraphy in 2500 African American, Hispanic, Asian American and Caucasian individuals ..
  40. Mechanisms of Sleep Disturbance in Children with Generalized Anxiety Disorder
    Candice A Alfano; Fiscal Year: 2013
    ..advanced training in pediatric sleep medicine, laboratory-based training in the use and interpretation of polysomnography, assessment of neurohormonal dimensions of arousal in anxious children, and further training in research ..
  41. Epidemiology of Brain Aging in the Very Old
    LON RAY WHITE; Fiscal Year: 2011
    ..Frozen blood samples and DNA are available for nearly all participants. Polysomnography studies and MRI scans are available on sub-samples, and extensive neuropathologic data are collected from ..
  42. Cardiovascular and Metabolic Risk Factors Associated with Short Sleep Duration
    Michael A Grandner; Fiscal Year: 2013
    ..in-lab study, will be used to gather standardized measures of sleep continuity and sleep architecture (via polysomnography), sleepiness (via a Multiple Sleep Latency Test), psychomotor performance (via the Psychomotor Vigilance Task)..
  43. Nocturnal Deterusor Overactivity In Overactive Bladder Syndrome
    Andrew D Krystal; Fiscal Year: 2012
    ..void volume as an indicator of detrusor instability, and nocturnal urine production rate) coincident with polysomnography during a single night in the sleep laboratory in: OAB patients with nocturia (N=76);NP patients without OAB (..
  44. Mechanisms of Sleepiness Symptoms in Sleep Apnea and Cardiovascular Disease
    Victoria M Pak; Fiscal Year: 2013
    ..Blood and urine samples will be obtained after polysomnography. EDS symptoms will also be measured by using the Epworth Sleepiness Scale (ESS) and the Psychomotor Vigilance ..
  45. Aging: Insomnia Treatment and Energy Balance
    Sarosh J Motivala; Fiscal Year: 2010
    ..insomnia have demonstrated consistent improvements in self-reported sleep, but outcome assessment, including polysomnography, behavioral factors such as health functioning and biologic factors impacted by sleep have not been ..
  46. Sleep Physiology and Risk for Alcohol Problems in Children of Alcoholics
    Maria M Wong; Fiscal Year: 2013
    ..controls over time via multiple measures of sleep, including self-report, parental ratings, actigraphy, and polysomnography;(ii) to understand the effects of sleep disturbances on neurocognitive functions, behavioral problems, and ..
  47. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel E Dimsdale; Fiscal Year: 2010
    ..admitted to the General Clinical Research Center for a 2-night stay during which they will complete overnight polysomnography, reactivity testing, and endothelial function testing...
  48. Sleep-Disordered Breathing and CPAP after Adenotonsillectomy in Children
    Ronald D Chervin; Fiscal Year: 2013
    ..Many sleep specialists now advocate for routine evaluation, by polysomnography or otherwise, after SDB is treated by adenotonsillectomy...
  49. Mechanisms of Sleep-Disordered Breathing in the Menopausal Transition
    Grace W Pien; Fiscal Year: 2010
    ..with nearly 10 years of previously collected hormonal and other data, for new data collected yearly by home polysomnography and other procedures...
  50. Behavioral Insomnia Therapy for those with Insomnia and Depression
    Colleen E Carney; Fiscal Year: 2012
    ..Objective (polysomnography, actigraph) and subjective (sleep diary, questionnaires) sleep measures, as well as depression and quality of ..
  51. Validation of Urinary Biomarkers in Diagnosis of Pediatric OSA
    David Gozal; Fiscal Year: 2012
    ..Thus, current diagnostic approaches for OSA require overnight polysomnography (PSG)...
  52. Pre- and Post-operative Differences in Brain and Sleep-related Events in Children
    Maria E Barnes; Fiscal Year: 2010
    ..I hypothesize that children diagnosed with OSA by overnight polysomnography (PSG) will exhibit differences in event-related potentials (ERPs) when presented with auditory and visual ..
  53. PAP adherence and real-world driving safety in OSA
    Matthew Rizzo; Fiscal Year: 2013
    ..using standardized neuropsychological tests;2) physiologic indices of disease severity from laboratory based polysomnography (PSG);3) extended measurements of real-world PAP adherence, sleep patterns, and self-ratings of sleepiness ..
  54. Role of Sleep in the Treatment of Cannabis Dependence
    Ryan G Vandrey; Fiscal Year: 2013
    ..Sleep assessments include polysomnography (intake, treatment weeks 1, 6, 10, and 12, and 3 month follow- up), actigraphy (daily) and sleep diaries (..
  55. National Sleep Research Resource (NSRR)
    Guo Qiang Zhang; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Since 1994, NIH has supported the standardized collection of polysomnography (PSG) studies as part of landmark multi-center studies which have used well-defined methods for data collection and ..
  56. Sleep Disturbances and Functional Decline in Elders
    ADAM PETER SPIRA; Fiscal Year: 2013
    ..SOF completed actigraphy (a means of measuring sleep by recording movement), and 3,006 completed ambulatory polysomnography at baseline and returned for follow-up 3.5 to 5 years later...
  57. Fibromyalgia and Sleep Treatments
    Nancy A Hamilton; Fiscal Year: 2010
    ..Many patients with FM report insomnia. However, in addition to difficulty initiating and maintaining sleep, polysomnography (i.e., overnight sleep studies) document frequent nighttime arousals...
  58. Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients
    Brian Gehlbach; Fiscal Year: 2012
    ..Sleep will be analyzed through the use of continuous polysomnography and circadian rhythmicity will be characterized through the measurement of core body temperature and urinary ..
  59. Statistical Methods for Developing RDoC-based Multidimensional Profiles
    MEREDITH JOANNE LOTZ WALLACE; Fiscal Year: 2013
    ..Wallace will develop clustering methods that incorporate intensively measured data captured through polysomnography, actigraphy, and daily self-report measures...
  60. Changes in Sleep and Cognition in Older Women
    Kristine Yaffe; Fiscal Year: 2013
    ..objectively measured characteristics of sleep, including wrist actigraphy (n=3,161) and overnight in-home polysomnography (n=461) obtained in primarily community-dwelling older women...
  61. Outcomes of Sleep Disorders in Older Men
    Katie L Stone; Fiscal Year: 2013
    ..Comprehensive and objective assessments of sleep (including overnight in-home polysomnography (PSG), 5-day wrist actigraphy and self-reported measures of sleep quality), adjudication of incident ..
  62. Using E-Diaries to Assess Sleep and Pain in Children and Adolescents with Sickle
    Cecelia R Valrie; Fiscal Year: 2013
    ..basis of sleep, to develop her skills to accurately assess sleep using physiological assessments, such as polysomnography and actigraphy, and paper measures, to expand her abilities to investigate, disseminate, and translate her ..
  63. Role of Sleep in Cognitive Declines in Normal Aging and Mild Cognitive Impairment
    MICHAEL SCULLIN; Fiscal Year: 2013
    ..they are either told will be important in the future or irrelevant in the future, and then they will take a polysomnography-recorded nap...
  64. ParkinStim: Transcranial Direct Current Stimulation for Parkinson's Disease
    DUSTIN ALLEN HELDMAN; Fiscal Year: 2012
    ..clinical study during which tDCS is applied to M1 while the subject sleeps in a sleep laboratory and standard polysomnography data is collected...
  65. SoundTrak: A Data Acquisition and Analysis System for OSDB
    B Parker; Fiscal Year: 2009
    ..Even without Pes, laboratory polysomnography (PSG) is a complex, burdensome, and costly procedure...
  66. PUPILLOMETRIC SLEEPINESS IN TREATED SLEEP DISORDERS
    Joan Shaver; Fiscal Year: 2003
    ..Currently, the extent of EDS is determined by polysomnography and the Multiple-Sleep Latency Test (MSLT), two EEG-based physiologic sleepiness measures that are labor ..
  67. Sleep disorders and QOL in lung cancer survivors
    Nalaka Gooneratne; Fiscal Year: 2009
    ..seeks to extend these findings by conducting a study in 280 long-term lung cancer survivors that incorporates polysomnography and pulmonary function measurements in a longitudinal design with a one-year follow-up reassessment;this is a ..
  68. Pain, Opioids, and Sleep in Cancer Patients
    Kathy Parker; Fiscal Year: 2006
    ..All subjects who meet the entrance criteria will be screened by one night of laboratory-based polysomnography to eliminate those with severe periodic leg movement disorder or sleep apnea syndrome...
  69. Effects of Zolpidem Extended-Release on Withdrawal and Sleep in Cannabis Users
    Ryan Vandrey; Fiscal Year: 2009
    ..Cannabis withdrawal severity, sleep polysomnography (PSG), performance on a comprehensive battery of state-of-the-art cognitive and psychomotor tests, and ..
  70. Outcomes of Sleep Disorders in Older Men- Reading Center
    Susan Redline; Fiscal Year: 2007
    ..of 3000 MrOS participants, we propose to add comprehensive and accurate assessments of sleep using in-home polysomnography, wrist actigraphy, questionnaires and other measures; and prospective adjudication of CVD events, to the ..
  71. Automated (AI) Analysis of Sleep Disordered Breathing
    Indu Ayappa; Fiscal Year: 2004
    ..disordered breathing (SDB) based solely on non-invasive cardiopulmonary signals collected during routine polysomnography. This will simplify, standardize and improve the diagnosis of SDB and facilitate research in this area...
  72. NEUROPSYCHOLOGY OF DEMENTIA WITH LEWY BODIES
    TANIS FERMAN; Fiscal Year: 2009
    ..whether DLB and not AD, is associated with disturbed sleep/wake mechanisms based on indices from polysomnography and multiple sleep latency tests...
  73. A Mouse Model of Inherited Frontal Lobe Epilepsy
    Jim Boulter; Fiscal Year: 2006
    ..Audiovisual monitoring and polysomnography reveals brief clusters of hyperkinetic motor seizures and vocalizations that begin during non-rapid eye ..