hand strength

Summary

Summary: Force exerted when gripping or grasping.

Top Publications

  1. ncbi Midlife hand grip strength as a predictor of old age disability
    T Rantanen
    Epidemiology, Demography and Biometry Program, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA
    JAMA 281:558-60. 1999
  2. pmc Objectively measured physical capability levels and mortality: systematic review and meta-analysis
    Rachel Cooper
    MRC Unit for Lifelong Health and Ageing and Division of Population Health, University College London, London WC1B 5JU
    BMJ 341:c4467. 2010
  3. ncbi Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia
    Fulvio Lauretani
    Geriatric Department, Italian National Insitute of Research and Care on Aging, Florence, Italy
    J Appl Physiol 95:1851-60. 2003
  4. pmc Objective measures of physical capability and subsequent health: a systematic review
    Rachel Cooper
    MRC Unit for Lifelong Health and Ageing, Division of Population Health, University College London, London, UK
    Age Ageing 40:14-23. 2011
  5. ncbi A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approach
    Helen C Roberts
    Academic Geriatric Medicine, University of Southampton, UK
    Age Ageing 40:423-9. 2011
  6. ncbi Sarcopenia and mortality risk in frail older persons aged 80 years and older: results from ilSIRENTE study
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    Age Ageing 42:203-9. 2013
  7. ncbi Coding and use of tactile signals from the fingertips in object manipulation tasks
    Roland S Johansson
    Physiology Section, Department of Integrative Medical Biology, Umea University, SE 901 87 Umea, Sweden
    Nat Rev Neurosci 10:345-59. 2009
  8. ncbi Functional magnetic resonance imaging reveals the neural substrates of arm transport and grip formation in reach-to-grasp actions in humans
    Cristiana Cavina-Pratesi
    Department of Psychology, Durham University, Durham DH13LE, United Kingdom
    J Neurosci 30:10306-23. 2010
  9. pmc Decoding complete reach and grasp actions from local primary motor cortex populations
    Carlos E Vargas-Irwin
    Department of Neuroscience, Brown University, Providence, Rhode Island 02912, USA
    J Neurosci 30:9659-69. 2010
  10. pmc Neural correlates of outcome after stroke: a cross-sectional fMRI study
    N S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, UK
    Brain 126:1430-48. 2003

Detail Information

Publications287 found, 100 shown here

  1. ncbi Midlife hand grip strength as a predictor of old age disability
    T Rantanen
    Epidemiology, Demography and Biometry Program, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA
    JAMA 281:558-60. 1999
    ..Poor muscle strength, functional limitations, and disability often coexist, but whether muscle strength during midlife predicts old age functional ability is not known...
  2. pmc Objectively measured physical capability levels and mortality: systematic review and meta-analysis
    Rachel Cooper
    MRC Unit for Lifelong Health and Ageing and Division of Population Health, University College London, London WC1B 5JU
    BMJ 341:c4467. 2010
    ....
  3. ncbi Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia
    Fulvio Lauretani
    Geriatric Department, Italian National Insitute of Research and Care on Aging, Florence, Italy
    J Appl Physiol 95:1851-60. 2003
    ..The findings of the study lay the basis for a cost-effective, clinical marker of sarcopenia based on a measure of isometric handgrip strength. Our findings should be verified in a longitudinal study...
  4. pmc Objective measures of physical capability and subsequent health: a systematic review
    Rachel Cooper
    MRC Unit for Lifelong Health and Ageing, Division of Population Health, University College London, London, UK
    Age Ageing 40:14-23. 2011
    ....
  5. ncbi A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approach
    Helen C Roberts
    Academic Geriatric Medicine, University of Southampton, UK
    Age Ageing 40:423-9. 2011
    ..Grip strength is recommended as a good simple measure of muscle strength when 'measured in standard conditions'. However, standard conditions remain to be defined...
  6. ncbi Sarcopenia and mortality risk in frail older persons aged 80 years and older: results from ilSIRENTE study
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    Age Ageing 42:203-9. 2013
    ..sarcopenia has been indicated as a reliable marker of frailty and poor prognosis among the oldest individuals. We evaluated the impact of sarcopenia on the risk of all-cause death in a population of frail older persons living in community...
  7. ncbi Coding and use of tactile signals from the fingertips in object manipulation tasks
    Roland S Johansson
    Physiology Section, Department of Integrative Medical Biology, Umea University, SE 901 87 Umea, Sweden
    Nat Rev Neurosci 10:345-59. 2009
    ..Analysis of signals in tactile afferent neurons and central processes in humans reveals how contact events are encoded and used to monitor and update task performance...
  8. ncbi Functional magnetic resonance imaging reveals the neural substrates of arm transport and grip formation in reach-to-grasp actions in humans
    Cristiana Cavina-Pratesi
    Department of Psychology, Durham University, Durham DH13LE, United Kingdom
    J Neurosci 30:10306-23. 2010
    ....
  9. pmc Decoding complete reach and grasp actions from local primary motor cortex populations
    Carlos E Vargas-Irwin
    Department of Neuroscience, Brown University, Providence, Rhode Island 02912, USA
    J Neurosci 30:9659-69. 2010
    ....
  10. pmc Neural correlates of outcome after stroke: a cross-sectional fMRI study
    N S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, UK
    Brain 126:1430-48. 2003
    ..These results further our understanding of the recovery process by demonstrating for the first time a clear relationship between task-related activation of the motor system and outcome after stroke...
  11. pmc Dynapenia and aging: an update
    Todd M Manini
    Institute on Aging and Department of Aging and Geriatric Research, University of Florida, Gainesville, FL 32611, USA
    J Gerontol A Biol Sci Med Sci 67:28-40. 2012
    ..However, these efforts are expected to provide a specific understanding of the role that dynapenia plays in the loss of physical function and increased risk for disability among older adults...
  12. ncbi The impact of supplemental n-3 long chain polyunsaturated fatty acids and dietary antioxidants on physical performance in postmenopausal women
    H L Hutchins-Wiese
    Center on Aging, MC 5215, University of Connecticut Health Center Farmington, CT 06030 5215, USA
    J Nutr Health Aging 17:76-80. 2013
    ..Identify relationships and evaluate effects of long chain polyunsaturated fatty acids (LCPUFA) on frailty and physical performance...
  13. ncbi Low vitamin D status has an adverse influence on bone mass, bone turnover, and muscle strength in Chinese adolescent girls
    Leng Huat Foo
    Faculty of Veterinary Science, University of Sydney, Sydney 2006, Australia
    J Nutr 139:1002-7. 2009
    ..These findings suggest that adequate vitamin D status during adolescence is important for optimizing bone mass, which may lead to higher peak bone mass at maturity. Poor vitamin D status also compromises forearm muscle strength...
  14. ncbi Grip strength, body composition, and mortality
    Catharine R Gale
    MRC Epidemiology Resource Centre, University of Southampton, Southampton General Hospital, Southampton, UK
    Int J Epidemiol 36:228-35. 2007
    ..We investigated the relation between grip strength, body composition, and cause-specific and total mortality in 800 men and women aged 65 and over...
  15. ncbi Grip strength, postural control, and functional leg power in a representative cohort of British men and women: associations with physical activity, health status, and socioeconomic conditions
    Diana Kuh
    MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, 1 19 Torrington Place, London, United Kingdom, WC1E 6BT
    J Gerontol A Biol Sci Med Sci 60:224-31. 2005
    ....
  16. pmc Age-related changes in the neural correlates of motor performance
    N S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, UK
    Brain 126:873-88. 2003
    ..These results support the notion that an adaptable and plastic motor network is able to respond to age-related degenerative changes in order to maintain performance levels...
  17. ncbi Task-dependent modulations of cortical oscillatory activity in human subjects during a bimanual precision grip task
    J M Kilner
    Sobell Department of Neurophysiology, Institute of Neurology, Queen Square, London, United Kingdom
    Neuroimage 18:67-73. 2003
    ....
  18. pmc Contributions of descending and ascending pathways to corticomuscular coherence in humans
    Claire L Witham
    Institute of Neuroscience, Newcastle University, Henry Wellcome Building for Neuroecology, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
    J Physiol 589:3789-800. 2011
    ..These results confirm the complex nature of corticomuscular coherence with contributions from both descending and ascending pathways...
  19. ncbi Patterns of muscle activity underlying object-specific grasp by the macaque monkey
    T Brochier
    Sobell Dept of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London WC1N 3BG, UK
    J Neurophysiol 92:1770-82. 2004
    ..These results identify the specific patterns of activity required to achieve distinct hand postures for grasping, and they open the way to our understanding of how these patterns are generated by the central motor network...
  20. ncbi Predicting movement from multiunit activity
    Eran Stark
    Department of Physiology, Hadassah Medical School, Hebrew University, Jerusalem 91120, Israel
    J Neurosci 27:8387-94. 2007
    ....
  21. ncbi Hand strength: normative values
    C A Crosby
    Pennsylvania Hand Center, Bryn Mawr 19010
    J Hand Surg Am 19:665-70. 1994
    We studied normal hand strength and the difference between dominant and nondominant hands. Two hundred fourteen volunteers were tested with a calibrated Jamar dynamometer at all five levels...
  22. pmc Absolute strength and loss of strength as predictors of mobility decline in older adults: the InCHIANTI study
    Gregory E Hicks
    Department of Physical Therapy, University of Delaware, Newark, DE 19716, USA
    J Gerontol A Biol Sci Med Sci 67:66-73. 2012
    ..This study sought to identify sex-specific cutpoints for muscle strength and power (at one time point) and 3-year changes in strength and power that would maximize prediction of 3-year mobility decline...
  23. ncbi Decoding natural grasp types from human ECoG
    Tobias Pistohl
    Bernstein Center Freiburg BCF, 79104 Freiburg, Germany
    Neuroimage 59:248-60. 2012
    ..We conclude that ECoG signals are promising candidates for BMIs that include the restoration of grasping movements...
  24. pmc Physical activity across adulthood and physical performance in midlife: findings from a British birth cohort
    Rachel Cooper
    MRC Unit for Lifelong Health and Ageing, Division of Population Health, University College London, United Kingdom
    Am J Prev Med 41:376-84. 2011
    ..It is unclear whether the benefits of physical activity accumulate across life or whether there are sensitive periods when physical activity is more influential...
  25. ncbi Delayed visual feedback affects both manual tracking and grip force control when transporting a handheld object
    Fabrice R Sarlegna
    Institute of Movement Sciences, Centre National de la Recherche Scientifique and Université de la Méditerranée, Marseille, France
    J Neurophysiol 104:641-53. 2010
    ..Overall, our findings support the idea that visual feedback of object motion can influence the predictive control of grip force even when the object is grasped...
  26. ncbi Skeletal muscle strength as a predictor of all-cause mortality in healthy men
    E Jeffrey Metter
    National Institute on Aging, Gerontology Research Center, Baltimore, Maryland 21224, USA
    J Gerontol A Biol Sci Med Sci 57:B359-65. 2002
    ..Strength and rate of change in strength contribute to the impact of sarcopenia on mortality. Although muscle mass and physical activity are important, they do not completely account for the impact of strength and changes in strength...
  27. ncbi Cortical connections of the macaque anterior intraparietal (AIP) area
    Elena Borra
    Dipartimento di Neuroscienze, Sezione di Fisiologia, Universita di Parma, I43100 Parma, Italy
    Cereb Cortex 18:1094-111. 2008
    ..Thus, AIP could represent a crucial node in a cortical circuit in which hand-related sensory and motor signals gain access to representations of object identity for tactile object recognition...
  28. pmc The cognitive neuroscience of prehension: recent developments
    Scott T Grafton
    Department of Psychology, SAGE Center for the Study of Mind, University of California at Santa Barbara, Santa Barbara, CA 93106, USA
    Exp Brain Res 204:475-91. 2010
    ..The review ends with a consideration about how prehension fits within larger action repertoires that solve more complex goals and the possible cortical architectures needed to organize these actions...
  29. ncbi Elbow position affects handgrip strength in adolescents: validity and reliability of Jamar, DynEx, and TKK dynamometers
    Vanesa España-Romero
    Department of Physiology, School of Medicine, University of Granada, Granada, Spain
    J Strength Cond Res 24:272-7. 2010
    ..The present study provides useful and relevant information indicating which elbow position, and which type of dynamometer, yield maximal handgrip strength in adolescents...
  30. ncbi Hand-grip dynamometry predicts future outcomes in aging adults
    Richard W Bohannon
    Department of Physical Therapy, Neag School of Education, University of Connecticut, Storrs, CT 06269 2101, USA
    J Geriatr Phys Ther 31:3-10. 2008
    ..One use of clinical measures is the prediction of future outcomes. The purpose of this systematic review was to summarize the literature addressing the value of grip strength as a predictor of important outcomes...
  31. ncbi Disconnecting force from money: effects of basal ganglia damage on incentive motivation
    Liane Schmidt
    Laboratoire INSERM U610, Institut Fédératif de Recherches en Neurosciences, Universite Pierre et Marie Curie Paris 6, Site Pitié Salpêtrière, F 75013 Paris, France
    Brain 131:1303-10. 2008
    ..We conclude that bilateral striato-pallidal damage specifically disconnects motor output from affective evaluation of potential rewards...
  32. pmc Anticipatory planning and control of grasp positions and forces for dexterous two-digit manipulation
    Qiushi Fu
    Department of Kinesiology, Arizona State University, Tempe, Arizona 85287 0404, USA
    J Neurosci 30:9117-26. 2010
    ..These results are discussed in the context of motor equivalence and sensorimotor integration of grasp kinematics and kinetics...
  33. pmc Neural correlates of age-related changes in cortical neurophysiology
    P Talelli
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College, London, UK
    Neuroimage 40:1772-81. 2008
    ....
  34. pmc The relationship between brain activity and peak grip force is modulated by corticospinal system integrity after subcortical stroke
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, and Department of Brain Repair and Rehabilitation, Institute of Neurology, University College London, London, UK
    Eur J Neurosci 25:1865-73. 2007
    ..These findings suggest that the premotor cortices might play a new and functionally relevant role in controlling force production in patients with more severe corticospinal system disruption...
  35. ncbi Handgrip strength as a predictor of functional, psychological and social health. A prospective population-based study among the oldest old
    Diana G Taekema
    Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands
    Age Ageing 39:331-7. 2010
    ..Muscle strength measurements could be useful as part of a clinical evaluation of oldest old patients to determine who are most at risk of accelerated decline in the near future...
  36. ncbi Sarcopenia in elderly men and women: the Rancho Bernardo study
    Edward M Castillo
    Joint Doctoral Program, Public Health, San Diego State University University of California, San Diego, La Jolla, California, USA
    Am J Prev Med 25:226-31. 2003
    ..Sarcopenia risk factors are poorly understood...
  37. ncbi Control strategies in object manipulation tasks
    J Randall Flanagan
    Department of Psychology, Centre for Neuroscience Studies, Queen s University, Kingston, ON, K7L 3N6, Canada
    Curr Opin Neurobiol 16:650-9. 2006
    ..Successful manipulation requires the ability both to predict the motor commands required to grasp, lift, and move objects and to predict the sensory events that arise as a consequence of these commands...
  38. ncbi Human cortical control of hand movements: parietofrontal networks for reaching, grasping, and pointing
    Flavia Filimon
    Max Planck Institute for Human Development, Berlin, Germany
    Neuroscientist 16:388-407. 2010
    ..The available evidence supports a cortical organization along gradients of sensory (visual to somatosensory) and effector (eye to hand) preferences...
  39. ncbi Functional properties of grasping-related neurons in the ventral premotor area F5 of the macaque monkey
    Vassilis Raos
    Dipartimento di Neuroscienze, Sezione di Fisiologia, Universita di Parma, Parma, Italy
    J Neurophysiol 95:709-29. 2006
    ....
  40. ncbi The role of synchrony and oscillations in the motor output
    S N Baker
    Sobell Department of Neurophysiology, Institute of Neurology, Queen Square, London, WC1N 3BG, UK
    Exp Brain Res 128:109-17. 1999
    ..A speculative hypothesis is presented on the role of synchronous oscillations in the motor system, which is consistent with experimental observations to date...
  41. pmc Motor assessment using the NIH Toolbox
    David B Reuben
    Division of Geriatrics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
    Neurology 80:S65-75. 2013
    ....
  42. ncbi Age trajectories of grip strength: cross-sectional and longitudinal data among 8,342 Danes aged 46 to 102
    Henrik Frederiksen
    Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark
    Ann Epidemiol 16:554-62. 2006
    ..The purpose is to study the age trajectory of hand-grip strength after the age of 45 years...
  43. pmc Performance measures predict onset of activity of daily living difficulty in community-dwelling older adults
    Wen Ni Wennie Huang
    Department of Physical Therapy, I Shou University, Kaohsiung, Taiwan
    J Am Geriatr Soc 58:844-52. 2010
    ..To assess the predictive value of five performance-based measures for the onset of difficulty in activities of daily living (ADLs)...
  44. pmc Decoding 3D reach and grasp from hybrid signals in motor and premotor cortices: spikes, multiunit activity, and local field potentials
    Arjun K Bansal
    Department of Neuroscience, Brown University, Providence, RI, USA
    J Neurophysiol 107:1337-55. 2012
    ..For BCIs, our results indicate that neuronal ensemble spiking is the preferred signal for decoding, while LFPs and combined signals from PMv and MI can add robustness to BCI control...
  45. ncbi Simultaneous recording of macaque premotor and primary motor cortex neuronal populations reveals different functional contributions to visuomotor grasp
    M A Umilta
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, UK
    J Neurophysiol 98:488-501. 2007
    ....
  46. ncbi What does the brain do when you fake it? An FMRI study of pantomimed and real grasping
    G Kroliczak
    Canadian Institutes of Health Research Group in Action and Perception, Department of Psychology, University of Western Ontario, London, Canada
    J Neurophysiol 97:2410-22. 2007
    ..Moreover, pantomimed grasping may not tap object-related areas within the ventral stream, but rather may rely on mechanisms within the right hemisphere that are recruited by artificial and less practiced actions...
  47. ncbi Tie my hands, tie my eyes
    Ettore Ambrosini
    Laboratory of Neuropsychology and Cognitive Neuroscience, University G D Annunzio, Chieti, Italy
    J Exp Psychol Hum Percept Perform 38:263-6. 2012
    ..This suggests, for the first time, that actions are observed best when we are actually in the position to perform them...
  48. ncbi Sarcopenia and osteopenia among 70-80-year-old home-dwelling Finnish women: prevalence and association with functional performance
    R Patil
    The UKK Institute for Health Promotion Research, PO Box 30, 33501 Tampere, Finland
    Osteoporos Int 24:787-96. 2013
    ..Muscle mass and derived indices of sarcopenia were not significantly related to measures of functional ability...
  49. pmc Force-independent distribution of correlated neural inputs to hand muscles during three-digit grasping
    Brach Poston
    Department of Kinesiology, Arizona State University, Tempe, Arizona 85287 0404, USA
    J Neurophysiol 104:1141-54. 2010
    ..0039). These findings indicate that the distribution of neural drive to multiple hand muscles is force independent and may reflect the anatomical properties or functional roles of hand muscle groups...
  50. ncbi Memory mechanisms in grasping
    Constanze Hesse
    Experimental Psychology, University of Giessen, Germany
    Neuropsychologia 47:1532-45. 2009
    ..Therefore, the authors propose that grasping after a delay is guided by classic memory mechanisms and that this is reflected in an increasing maximum grip aperture in grasping...
  51. ncbi Where one hand meets the other: limb-specific and action-dependent movement plans decoded from preparatory signals in single human frontoparietal brain areas
    Jason P Gallivan
    Brain and Mind Institute, Natural Sciences Centre and Department of Psychology, University of Western Ontario, London, Ontario, Canada
    J Neurosci 33:1991-2008. 2013
    ....
  52. pmc Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS)
    Harnish P Patel
    MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK
    Age Ageing 42:378-84. 2013
    ..The aim of this study was to describe the prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) consensus definition...
  53. pmc Subthalamic nucleus activity optimizes maximal effort motor responses in Parkinson's disease
    Anam Anzak
    Functional Neurosurgery Experimental Neurology Group, Department of Clinical Neurology, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK
    Brain 135:2766-78. 2012
    ....
  54. ncbi Getting a grip on numbers: numerical magnitude priming in object grasping
    Oliver Lindemann
    Nijmegen Institute for Cognition and Information, Radboud University Nijmegen, The Netherlands
    J Exp Psychol Hum Percept Perform 33:1400-9. 2007
    ..The data indicate a priming of size-related motor features by numerals and support the idea that representations of numbers and actions share common cognitive codes within a generalized magnitude system...
  55. ncbi The cortical control of visually guided grasping
    Umberto Castiello
    Dipartimento di Psicologia Generale Università di Padova, Padova, Italy
    Neuroscientist 14:157-70. 2008
    ..It compares and summarizes results from behavioral neuroscience, electrophysiology, and neuroimaging to provide a detailed description of the neural circuits that facilitate the formation of grip patterns in human and nonhuman primates...
  56. ncbi Developmental origins of midlife grip strength: findings from a birth cohort study
    Diana Kuh
    MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, UK
    J Gerontol A Biol Sci Med Sci 61:702-6. 2006
    ..We tested whether prepubertal growth, pubertal growth, or the development of motor and cognitive capabilities was associated with midlife muscle strength independently of other determinants of grip strength...
  57. pmc Hand-grip strength cut points to screen older persons at risk for mobility limitation
    Janne Sallinen
    Gerontology Research Centre, Department of Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland
    J Am Geriatr Soc 58:1721-6. 2010
    ..To determine optimal hand-grip strength cut points for likelihood of mobility limitation in older people and to study whether these cut points differ according to body mass index (BMI)...
  58. pmc Cutpoints for low appendicular lean mass that identify older adults with clinically significant weakness
    Peggy M Cawthon
    California Pacific Medical Center Research Institute, 185 Berry Street, Suite 5700, San Francisco, CA 94107 1762
    J Gerontol A Biol Sci Med Sci 69:567-75. 2014
    ....
  59. ncbi Motor control strategies in a continuous task space
    Christoph Schütz
    Faculty of Psychology and Sport Sciences, Bielefeld University, Bielefeld, Germany
    Motor Control 15:321-41. 2011
    ..Experimental results further revealed a work range restriction effect, which was reproduced for the dominant and the nondominant hand...
  60. ncbi Ventral premotor and inferior parietal cortices make distinct contribution to action organization and intention understanding
    Luca Bonini
    Dipartimento di Neuroscienze, Universita degli Studi di Parma, Parma, Italy
    Cereb Cortex 20:1372-85. 2010
    ..Furthermore, the similarities between MNs properties of the 2 areas indicate that they constitute a functional circuit underlying others' intention understanding...
  61. ncbi Clinical burden of erosive hand osteoarthritis and its relationship to nodes
    J Bijsterbosch
    Leiden University Medical Centre, Department of Rheumatology, C1 R, P O Box 9600, 2300 RC Leiden, The Netherlands
    Ann Rheum Dis 69:1784-8. 2010
    ..To describe the clinical burden of erosive osteoarthritis (EOA) of the hand in terms of pain, functioning and health-related quality of life (HRQL) and its relationship to nodal osteoarthritis (OA)...
  62. pmc Heterogeneity in rate of decline in grip, hip, and knee strength and the risk of all-cause mortality: the Women's Health and Aging Study II
    Qian Li Xue
    Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    J Am Geriatr Soc 58:2076-84. 2010
    ..To assess the relationship between rate of change in muscle strength and all-cause mortality...
  63. ncbi Reference equations for the performance of healthy adults on field walking tests
    Victor Zuniga Dourado
    Universidade Federal de Sao Paulo, Santos, SP, Brasil
    J Bras Pneumol 37:607-14. 2011
    ..To develop regression equations for predicting six-minute and incremental shuttle walk distances (6MWD and ISWD, respectively), based on demographic characteristics, anthropometric variables, and grip strength...
  64. ncbi Force coordination in static manipulation tasks performed using standard and non-standard grasping techniques
    Paulo B de Freitas
    Human Performance Lab, Department of Health, Nutrition, and Exercise Sciences, University of Delaware, 547 South College Avenue, Newark, DE 19716, USA
    Exp Brain Res 194:605-18. 2009
    ....
  65. ncbi Association between lean mass and handgrip strength with bone mineral density in physically active postmenopausal women
    Rosangela Villa Marin
    Physical Fitness Research Center of São Caetano do Sul CELAFISCS, Sao Paulo, Brazil
    J Clin Densitom 13:96-101. 2010
    ..Our results suggest that strategies aiming to improve muscle strength and lean mass must contribute to the bone health of physically active postmenopausal women...
  66. ncbi Validity and reproducibility of hand-held dynamometry in children aged 4-11 years
    Willeke A van den Beld
    Department of Rehabilitation Medicine and Interdisciplinary Child Neurology Centre, University Medical Centre, Nijmegen St Radboud, Nijmegen, The Netherlands
    J Rehabil Med 38:57-64. 2006
    ..To evaluate validity and reproducibility of hand-held dynamometry in 11 different muscle groups in children...
  67. ncbi Planning of visually guided reach-to-grasp movements: inference from reaction time and contingent negative variation (CNV)
    Manuel Zaepffel
    Institut de Neurosciences Cognitives de la Mediterranee, UMR 6193, CNRS, Universite de la Mediterranee, Marseille, France
    Psychophysiology 49:17-30. 2012
    ..Finally, we outline the composite nature of the lCNV that might reflect both high- and low-level planning processes...
  68. pmc Decoding of grasping information from neural signals recorded using peripheral intrafascicular interfaces
    Silvestro Micera
    BioRobotics Institute, Scuola Superiore Sant Anna, Pisa, Italy
    J Neuroeng Rehabil 8:53. 2011
    ..This goal can be achieved with several approaches and among them, the use of implantable interfaces connected with the peripheral nervous system, namely intrafascicular electrodes, is considered particularly interesting...
  69. pmc Causal connectivity between the human anterior intraparietal area and premotor cortex during grasp
    Marco Davare
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK
    Curr Biol 20:176-81. 2010
    ..These findings suggest that grasp-related and muscle-specific PMv-M1 interactions are driven by information about object properties provided by AIP...
  70. ncbi Synchronization in monkey motor cortex during a precision grip task. II. effect of oscillatory activity on corticospinal output
    Stuart N Baker
    Sobell Department of Neurophysiology, Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom
    J Neurophysiol 89:1941-53. 2003
    ..The oscillations will therefore be effectively transmitted to spinal motoneurons, and this has important consequences for the possible role of oscillations in motor control of the hand...
  71. ncbi Ipsilateral motor dysfunction from unilateral stroke: implications for the functional neuroanatomy of hemiparesis
    O Noskin
    Neurological Institute of New York, Columbia University Medical Center, New York, NY 10032, USA
    J Neurol Neurosurg Psychiatry 79:401-6. 2008
    ..By tracking motor function of both hands beginning in the acute stroke period in patients with cortical versus subcortical lesions, we sought to understand the functional anatomy of the ipsilateral deficit...
  72. ncbi Hand grip strength: outcome predictor and marker of nutritional status
    Kristina Norman
    Department of Gastroenterology, Hepatology and Endocrinology, Charite University Medicine Berlin, Berlin, Germany
    Clin Nutr 30:135-42. 2011
    ..This review outlines the prognostic relevance of grip strength in various clinical and epidemiologic settings and investigates its suitability as marker of nutritional status in cross-sectional as well as intervention studies...
  73. ncbi Testosterone, physical activity, and somatic outcomes among Filipino males
    Lee T Gettler
    Department of Anthropology, Northwestern University, Evanston, IL 60208, USA
    Am J Phys Anthropol 142:590-9. 2010
    ....
  74. ncbi Attenuation of corticomuscular coherence with additional motor or non-motor task
    Ashley N Johnson
    School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA
    Clin Neurophysiol 122:356-63. 2011
    ..Additionally, we examined the potential associations between corticomuscular coherence and fine motor performance...
  75. ncbi Association between functional capacity tests and fractures: an eight-year prospective population-based cohort study
    M Karkkainen
    Bone and Cartilage Research Unit, University of Kuopio, P O Box 1627, MediTeknia Building, 70211 Kuopio, Finland
    Osteoporos Int 19:1203-10. 2008
    ..The standing-on-one-foot and grip strength tests and a question about self-assessed ability to move can be used to identify women with a high risk of suffering a fracture...
  76. ncbi Effects of object shape and visual feedback on hand configuration during grasping
    Luis F Schettino
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    Exp Brain Res 151:158-66. 2003
    ....
  77. ncbi Functional properties of grasping-related neurons in the dorsal premotor area F2 of the macaque monkey
    Vassilis Raos
    Dipartimento di Neuroscienze, Sezione di Fisiologia, Universita di Parma, 43100 Parma, Italy
    J Neurophysiol 92:1990-2002. 2004
    ..These results indicate an important role of F2 in the control of goal-related hand movements...
  78. ncbi Grip strength predicts cause-specific mortality in middle-aged and elderly persons
    Hideo Sasaki
    Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan
    Am J Med 120:337-42. 2007
    ..Handgrip strength is a simple measurement used to estimate overall muscle strength but might also serve as a predictor of health-related prognosis. We investigated grip strength-mortality association in a longitudinal study...
  79. ncbi Walking speed as a good predictor for the onset of functional dependence in a Japanese rural community population
    S Shinkai
    Department of Community Health, Tokyo Metropolitan Institute of Gerontology, Japan
    Age Ageing 29:441-6. 2000
    ..to investigate and compare the predictive values of four physical performance measures for the onset of functional dependence in older Japanese people living at home...
  80. ncbi Task goal and grip force dynamics
    Kimberlee Jordan
    Department of Kinesiology, 266 Recreation Building, The Pennsylvania State University, University Park, PA 16802, USA
    Exp Brain Res 156:451-7. 2004
    ..Theorizing about the organization of isometric force output should include the effects of task goals as well as the level of force per se...
  81. pmc Grasping the intentions of others with one's own mirror neuron system
    Marco Iacoboni
    Ahmanson Lovelace Brain Mapping Center, Neuropsychiatric Institute, David Geffen School of Medicine, University of California, Los Angeles, California, USA
    PLoS Biol 3:e79. 2005
    ..To ascribe an intention is to infer a forthcoming new goal, and this is an operation that the motor system does automatically...
  82. pmc How objects are grasped: the interplay between affordances and end-goals
    Luisa Sartori
    Dipartimento di Psicologia Generale, Universita di Padova, Padova, Italy
    PLoS ONE 6:e25203. 2011
    ..Little is known about how the placement of individual fingers on objects is affected by the end-goal of the action...
  83. ncbi Cortical excitability changes following grasping exercise augmented with electrical stimulation
    Gergely I Barsi
    Center for Sensory Motor Interaction, Department of Health Science and Technology, Aalborg University, Fredrik Bajers Vej 7 D 3, 9220, Aalborg, Denmark
    Exp Brain Res 191:57-66. 2008
    ....
  84. ncbi How predictive is grip force control in the complete absence of somatosensory feedback?
    Dennis A Nowak
    Department of Neurology and Clinical Neurophysiology, Academic Hospital Munchen Bogenhausen, Technical University of Munich, Englschalkingerstrasse 77, D 81925 Munich, Germany
    Brain 127:182-92. 2004
    ..We conclude that predictive grip force control requires at least intermittent sensory feedback to signal the effectiveness of descending motor commands and to update internal models...
  85. ncbi Finger interaction during accurate multi-finger force production tasks in young and elderly persons
    Minoru Shinohara
    Department of Integrative Physiology, University of Colorado, CO 80309, Boulder, USA
    Exp Brain Res 156:282-92. 2004
    ..This general result underscores the importance of efforts to analyze motor coordination using control rather than performance variables...
  86. ncbi Internal models underlying grasp can be additively combined
    Paul R Davidson
    Sobell Dept of Motor Neuroscience, Institute of Neurology, University College London, Queen Square, WC1 N 3BG, London, UK
    Exp Brain Res 155:334-40. 2004
    ..Results show that subjects can additively combine internal models of object dynamics but the sum is biased by a default estimate of the object's weight...
  87. ncbi Is grip strength associated with health-related quality of life? Findings from the Hertfordshire Cohort Study
    Avan Aihie Sayer
    MRC Epidemiology Resource Centre, University of Southampton, Southampton, UK
    Age Ageing 35:409-15. 2006
    ..to investigate the relationship between grip strength and health-related quality of life (HRQoL)...
  88. ncbi Get aroused and be stronger: emotional facilitation of physical effort in the human brain
    Liane Schmidt
    Institut du Cerveau et de la Moëlle épinière ICM, INSERM UMRS 975, Paris, France
    J Neurosci 29:9450-7. 2009
    ..We suggest that this region, by driving the motor cortex, constitutes a brain pathway that allows emotional arousal to facilitate physical effort...
  89. ncbi Does the intention to communicate affect action kinematics?
    Luisa Sartori
    Dipartimento di Psicologia Generale, Universita di Padova, Italy
    Conscious Cogn 18:766-72. 2009
    ..Results are discussed in terms of cognitive pragmatics and current knowledge on how social behavior shapes action kinematics...
  90. ncbi The effect of obstacle position on reach-to-grasp movements
    M Mon-Williams
    School of Psychology, University of St Andrews, St Andrews, Fife, KY16 9JU, Scotland, UK
    Exp Brain Res 137:497-501. 2001
    ..These results show that the anticipated likelihood of a collision with potential obstacles affects the planning of movement duration and maximum grip aperture in prehension...
  91. ncbi Is there an association between serum 25-hydroxyvitamin D concentration and muscle strength among older women? Results from baseline assessment of the EPIDOS study
    C Annweiler
    Department of Geriatrics, Angers University Hospital, France
    J Nutr Health Aging 13:90-5. 2009
    ....
  92. ncbi Epidemiology of balance and dizziness in a national population: findings from the English Longitudinal Study of Ageing
    Kara N Stevens
    Peninsula Medical School, Epidemiology and Public Health Group, UK
    Age Ageing 37:300-5. 2008
    ..to identify socio-economic, behavioural and disease status risks for impaired balance or self-reported dizziness in older people from a large population-based study...
  93. ncbi Visually guided grasping produces fMRI activation in dorsal but not ventral stream brain areas
    Jody C Culham
    Department of Psychology, University of Western Ontario, London, Ontario, N6A 5C2, Canada
    Exp Brain Res 153:180-9. 2003
    ..These results suggest that dorsal areas, including AIP, but not ventral areas such as LOC, play a fundamental role in computing object properties during grasping...
  94. pmc Age-dependent changes in the neural correlates of force modulation: an fMRI study
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
    Neurobiol Aging 29:1434-46. 2008
    ..These results indicate that a reduced ability to modulate activity in appropriate motor networks when required may contribute to age-related decline in motor performance...
  95. ncbi Gamma-range corticomuscular coherence during dynamic force output
    Wolfgang Omlor
    Neurological Clinic, Albert Ludwigs University, Breisacher Strasse 64, 79106 Freiburg, Germany
    Neuroimage 34:1191-8. 2007
    ....
  96. ncbi The cortical motor system
    G Rizzolatti
    Istituto di Fisiologia Umana, Universita di Parma, Via Volturno 39, I43100 Parma, Italy
    Neuron 31:889-901. 2001
    ..We submit that generating internal representations of actions is central to cortical motor function. External contingencies and motivational factors determine then whether these action representations are transformed into actual actions...
  97. ncbi The impact of stroke on the performance of grasping: usefulness of kinetic and kinematic motion analysis
    Dennis A Nowak
    Department of Neurology, University of Cologne, Cologne, Germany
    Neurosci Biobehav Rev 32:1439-50. 2008
    ....
  98. pmc Exposure-dependent increases in IL-1beta, substance P, CTGF, and tendinosis in flexor digitorum tendons with upper extremity repetitive strain injury
    Jane M Fedorczyk
    Department of Physical Therapy and Rehabilitation Sciences, Drexel University, 245 North 15th Street, MS502, Philadelphia, Pennsylvania 19102, USA
    J Orthop Res 28:298-307. 2010
    ....
  99. ncbi Objects automatically potentiate action: an fMRI study of implicit processing
    J Grezes
    Wellcome Department of Imaging Neuroscience, University College London, 12 Queen Square, London WC1N 3BG, London, UK
    Eur J Neurosci 17:2735-40. 2003
    ....
  100. pmc A comparison of frailty indexes for the prediction of falls, disability, fractures, and mortality in older men
    Kristine E Ensrud
    Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
    J Am Geriatr Soc 57:492-8. 2009
    ....
  101. ncbi Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons
    Michelangela Barbieri
    Department of Geriatric Medicine and Metabolic Diseases, II University of Naples, Italy
    Am J Physiol Endocrinol Metab 284:E481-7. 2003
    ..This mechanism may explain why IL-6 is a strong risk factor for disability...

Research Grants74

  1. Surgical Simulations to Optimize the Treatment of Wrist Osteoarthritis
    Jennifer A Nichols; Fiscal Year: 2013
    ..In Am 3, post-operative wrist and hand strength will be measured in vivo, and these data will be used in musculoskeletal computer models to evaluate how ..
  2. Quantifying the Recovery Response and Role of Hand Strength During Ladder Falls
    Na Jin Seo; Fiscal Year: 2013
    ..quantitative knowledge on biomechanical causes and recovery response from a ladder fall as well as the role of hand strength in recovering from a ladder slip and misstep...
  3. Nerve Stimulation to Improve Hand Weakness in Stroke
    ADRIANA CONFORTO; Fiscal Year: 2004
    ..collaboration for future studies regarding: effectiveness of electrical stimulation and training in improving hand strength and decreasing motor disability in chronic stroke patients; prognostic factors for response to rehabilitation ..
  4. EFFECTS OF MOVEMENT CONTEXT ON HEMIPARETIC GRASPING EARLY AFTER STROKE
    Catherine E Lang; Fiscal Year: 2010
    ..More successful performance during rehabilitation may also lead to more practice and use outside of rehabilitation. ..
  5. Control of Finger Movements after Stroke
    CATHERINE LANG; Fiscal Year: 2003
    ..Results from these experiments may assist rehabilitation professionals in designing and implementing rehabilitation strategies to improve hand function in people after stroke. ..
  6. fMRI Activity During the Visual Control of Force
    DAVID VAILLANCOURT; Fiscal Year: 2004
    ..These findings will have further implications for better understanding the visuomotor control deficits associated with aging, and diseased persons with Parkinson's disease, ataxia, and cerebellar deficits. ..
  7. Hand Function in Multiple Sclerosis
    Slobodan Jaric; Fiscal Year: 2006
    ....
  8. VESTIBULOSYMPATHETIC REFLEXES IN HUMANS
    CHESTER RAY; Fiscal Year: 2001
    ....
  9. NEURAL MECHANISMS OF CUTANEOUS SPATIAL INTEGRATION
    ESTHER GARDNER; Fiscal Year: 2008
    ..Principles of sensorimotor integration derived from this research may prove useful for developing better sensory prostheses or robotic manipulators based on biological models of hand function. ..
  10. Linking motor imagery to motor execution
    Sheng Li; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  11. NEUROINFORMATICS AND EYE-HAND COORDINATION
    ESTHER GARDNER; Fiscal Year: 2005
    ....
  12. Muscle Mechanosensitivity in Heart Failure
    Holly Middlekauff; Fiscal Year: 2004
    ..After a 4 week conditioning program, which reverses the myopathy of HF, the above testing repeated to determine if the muscle mechanoreceptor sensitization is reversible. ..
  13. Bilingual Speech Segmentation
    Daniel Weiss; Fiscal Year: 2006
    ..In sum, the proposed research will fill gaps in current knowledge regarding both bilingual language acquisition as well as statistical learning. ..
  14. Linkage Studies of Quantitative Ocular Traits
    Barbara Klein; Fiscal Year: 2006
    ..Subsequent follow-up with fine mapping of areas of interest in the genome is planned. ..
  15. OptiPush Wheelchair Training System
    W Richter; Fiscal Year: 2006
    ..Pre- and post-training evaluations will include exercise capacity, propulsion strength, propulsion efficiency and propulsion biomechanics testing. [unreadable] [unreadable]..
  16. Massaging Preterm Infants Enhances Growth
    Tiffany Field; Fiscal Year: 2006
    ..abstract_text> ..
  17. Antipsychotics: Temporal Effects on Cognitive Function
    Alvin Terry; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  18. ErgoChair Smart Manual Wheelchair
    W Richter; Fiscal Year: 2008
    ..This project will develop innovative technology that will dramatically improve the ergonomics of wheelchair transfers and lifting tasks. [unreadable] [unreadable]..
  19. Risk Factors and the Neurobiologic Substrate of Frailty
    Aron Buchman; Fiscal Year: 2009
    ..abstract_text> ..
  20. TESTOSTERONE FOR PREVENTION OF FRACTURE IN MEN
    Anne Kenny; Fiscal Year: 2005
    ....
  21. Neurohormonal Effects of Massage Therapy
    Tiffany Field; Fiscal Year: 2007
    ..The K05 would allow me to increase my research time including being mentored and mentoring students from 25 to 75% time. [unreadable] [unreadable] [unreadable]..
  22. Prenatal Depression and a Yoga Intervention
    Tiffany M Field; Fiscal Year: 2010
    ..We would expect that yoga would decrease depression, increase vagal activity, decrease cortisol and increase gestational age (decrease prematurity). ..
  23. THE SLEEP HEART HEALTH STUDY
    Anne Newman; Fiscal Year: 2007
    ..Accomplishing these goals will provide important information concerning the public health impact of SDB. [unreadable] [unreadable]..
  24. Cotinine for Cognitive Impairment in Neurological and Neuropsychiatric Disorders
    Alvin V Terry; Fiscal Year: 2010
    ..The partly translational design of the study will provide results leading to eventual clinical trials with cotinine or a relevant analog. ..
  25. Neuromuscular Fatigue in Older Adults
    Sandra Hunter; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  26. Detecting Endothelial Dysfunction in Renal Failure
    Julian Stewart; Fiscal Year: 2007
    ..These data will form the basis of future noninvasive prognostic testing and treatment of patients at risk for ECD and can provide a means to follow treatment modalities. [unreadable] [unreadable] [unreadable]..
  27. BENZODIAZEPINE USE AND RISK OF DISABILITY IN THE ELDERLY
    Shelly Gray; Fiscal Year: 2003
    ....
  28. Circulatory Dysfunction in Chronic Fatigue Syndrome
    Julian Stewart; Fiscal Year: 2004
    ....
  29. Spatial Attention in Visuomotor Processing
    TODD HANDY; Fiscal Year: 2005
    ....
  30. Family Clustering of Incidence & Progression of Cataract
    Barbara Klein; Fiscal Year: 2003
    ..We currently have no funds to support the proposed analyses. We believe this project offers the possibility of examining important hypotheses in a large group of families in a population-based framework. ..
  31. Task Dependence of Muscle Fatigue in Older Adults
    Sandra Hunter; Fiscal Year: 2005
    ..These preliminary findings will form the foundation for an RO 1 application that will further explore the mechanisms and task dependency of muscle fatigue in older adults. ..
  32. PROGRESSION OF NUCLEAR DENSITY OVER A 10-YEAR INTERVAL
    Barbara Klein; Fiscal Year: 2002
    ....
  33. EPIDEMIOLOGY OF CORONARY CALCIFICATION IN THE ELDERLY
    Anne Newman; Fiscal Year: 2005
    ..abstract_text> ..
  34. IGF-I/ALS Trial
    Eric Sorenson; Fiscal Year: 2007
    ..The preliminary data from our prior trial allows design of a phase III treatment trial that will yield a definitive result about the treatment effect of IGF-I. ..
  35. ORGANIZATION AND CONTROL OF MOVEMENT
    JOHN SOECHTING; Fiscal Year: 2007
    ..Providing sensory feedback would clearly enhance the efficacy of brain-machine interfaces and these results will provide new information about the normal utilization of sensory inflow in the control of movements. ..
  36. Knee Disorders and Occupational Biomechanical Risks
    Bryan Buchholz; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  37. The Family Blood Pressure Program (SAPPHIRe Network)
    JESS CURB; Fiscal Year: 2007
    ..unreadable] (End of Abstract) [unreadable] [unreadable]..
  38. Oxidative Stress and Vascular Function in Chronic Kidney Disease
    David Edwards; Fiscal Year: 2008
    ..Understanding these mechanisms may aid in the evaluation of therapies aimed at improving vascular function in chronic kidney disease. [unreadable] [unreadable] [unreadable]..
  39. TESTING THE EXERCISE PLUS PROGRAM FOLLOWING HIP FRACTURE
    Barbara Resnick; Fiscal Year: 2002
    ....
  40. DEVELOPMENT OF FUNCTIONAL LIMITATIONS IN THE BUILT ENVIRONMENT OF MID-AGED WOMEN
    Kristin Tomey; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  41. DEMENTIA IN SWEDISH TWINS
    Margaret Gatz; Fiscal Year: 2002
    ..Different diagnostic criteria will be compared. Quantitative indices will be derived from neuropsychological scores and from neuroimaging data subjected to quantitative mapping. ..
  42. Dementia in Swedish Twins Data Archiving
    Margaret Gatz; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  43. Mechanisms of Atherosclerosis and CVD in HIV+ Women
    Robert Kaplan; Fiscal Year: 2009
    ..This investigation will have major implications for the development of strategies to predict, prevent, or reverse atherosclerosis in HIV- infected women. ..
  44. Magnetic Resonance in Peripheral Arterial Disease
    Mary Mcgrae McDermott; Fiscal Year: 2010
    ..This knowledge, in subsequent studies, is expected to lead to new therapies for PAD-related functional impairment and functional decline. ..
  45. Venous Hemodynamic Function in Older Hypertensive Adults
    WILLIAM FARQUHAR; Fiscal Year: 2006
    ....
  46. Phase II Therapeutic Trial of Mexiletine
    Richard J Barohn; Fiscal Year: 2010
    ..These secondary measures will be quantified by lndividual Neuromuscular Quality of Life (INQOL), SF-36 (adults), SF-10 (children), grip myotonia, physical exam, and electrophysiological testing, respectively. ..
  47. NIH OSTEOPOROSIS & RELATED BONE DISEASES RESOURCE CENTER
    Bess Dawson Hughes; Fiscal Year: 2002
    ..Specific efforts include supporting the National Osteoporosis Data Group, collecting and disseminating definitive statistics on bone diseases and on conditions co-morbid with osteoporosis, and preparing summary reports. ..
  48. POSTMENOPAUSAL HORMONAL REPLACEMENT THERAPY
    Wanpen Vongpatanasin; Fiscal Year: 2006
    ..The long-term goal of her work would be the discovery the most effective estrogen preparation that can prevent or treat hypertension in women after menopause. ..
  49. Genomic Characterization in Depression and Suicide.
    Etienne Sibille; Fiscal Year: 2007
    ..The training program proposes formal courses, supervised training and frequent interactions with several research groups involved in pioneering aspects of genomic research in mood disorders. [unreadable] [unreadable]..
  50. Cognitive-Emotional Integration in Adulthood and Aging
    Mark Lumley; Fiscal Year: 2007
    ..abstract_text> ..
  51. A Preclinical Model of Adolescent Toluene Abuse in Rats
    Scott Bowen; Fiscal Year: 2005
    ..The model also has the potential to assist in devising effective treatments and prevention strategies for adolescent inhalant abuse. ..
  52. Mechanisms of Disability in Peripheral Arterial Disease
    Mary McDermott; Fiscal Year: 2005
    ..Results will be used to develop interventions designed to improve lower extremity functioning and prevent functional decline in persons with PAD. ..
  53. Self-administration of abused inhalants in mice
    Scott Bowen; Fiscal Year: 2004
    ....
  54. Developing an Instrument to Measure Keyboarding Style
    Nancy Baker; Fiscal Year: 2006
    ..This information will be integrated into the final tool, the PECKS. The PECKS can then be used to identify an individual who have keyboarding...styles that have been associated with MSD-UE. ..
  55. ADJUNCT VITAMIN A THERAPY FOR TUBERCULOSIS AND HIV/AIDS
    Richard Semba; Fiscal Year: 2005
    ....
  56. Estimating Joint Impedance from the Surface EMG
    EDWARD CLANCY; Fiscal Year: 2004
    ..abstract_text> ..
  57. Task Practice Schedules to Enhance Recovery after Stroke
    Nicolas Schweighofer; Fiscal Year: 2006
    ..The hypothesis is that subjects with mild deficits benefit most from expanded variable practice, whereas subjects with moderate deficits benefit most from massed practice schedules. [unreadable] [unreadable]..
  58. COMMUNITY EPIDEMIOLOGIC STUDY OF CAREGIVING AND HEALTH
    Liesi Hebert; Fiscal Year: 2004
    ..Factors found to minimize negative health effects will provide potential interventions to minimize stress and maintain the health of older caregivers, and thereby minimize the social and economic impacts of caregiving. ..
  59. Development of Eye-Hand Coordination in Infant Reaching
    Daniela Corbetta; Fiscal Year: 2004
    ..From these data, hypotheses regarding the processes underlying the development of infants' eye-hand coordination in the 1st year will be assessed. ..
  60. fMRI and TMS of Motor Recovery after Hemiparetic Stroke
    Judith Schaechter; Fiscal Year: 2007
    ..abstract_text> ..
  61. Reactive astrocytes from gliotic capsule
    J Marc Simard; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  62. Regulation of Cell Signaling and Adhesion
    JOE RAMOS; Fiscal Year: 2006
    ..Moreover, this work will elucidate the potential role of PEA-15 in the pathogenesis of cancer and diabetes. ..
  63. Functional Substrates of Long-Term Motor Learning
    Scott Grafton; Fiscal Year: 2006
    ..The experiments demanding extensive practice are particularly relevant for developing rational pathophysiologic models of brain plasticity that are applicable to studies of functional recovery after stroke. [unreadable] [unreadable]..
  64. Aerobic Exercise, Diet and Cholesterol: A Meta-Analysis
    George A Kelley; Fiscal Year: 2010
    ..This is important since one of the major goals of the Department of Health and Human Services is to increase the quality and years of healthy life. ..
  65. Outcomes of Perinatal Stroke
    Meredith Golomb; Fiscal Year: 2008
    ..During the last year of the study, she plans to apply for an R01 grant to set up a pilot clinical trial. [unreadable] [unreadable]..
  66. Inflammatory response to sleep apnea in obese subjects
    JULIO ALONSO CHIRINOS MEDINA; Fiscal Year: 2010
    ..We propose that this study design will provide the best way to separate the independent effects of obesity and OSA on cardiovascular risk. ..
  67. EXERCISE AND BLOOD PRESSURE IN CHILDREN: A META-ANALYSIS
    George Kelley; Fiscal Year: 2001
    ..The investigators state that the results of this project will provide clarification regarding the role of exercise in reducing resting systolic and diastolic blood pressure in children and adolescents. ..
  68. Regulation of Cell Signaling and Adhesion
    JOE RAMOS; Fiscal Year: 2007
    ..This will determine if PEA-15 is a suitable target for the development of new cancer therapies and if it can be used as a marker for cancer progression. ..
  69. Gene-enviornment interactions in facial clefts
    Kaare Christensen; Fiscal Year: 2006
    ..This study will provide a new level of understanding for a complex birth defect trait. ..
  70. Repressive Style, suppression and chronic Pain
    John Burns; Fiscal Year: 2004
    ..Moreover, findings should provide theoretical principles on which to found new intervention strategies (e.g., "regulating" suppression by engaging in cognitive exercises). ..
  71. TRAINING IN COGNITIVE AND COMPUTATIONAL NEUROSCIENCE
    Michael Arbib; Fiscal Year: 2002
    ..The plan for the postdoctoral position focuses on permitting a student trained in psychology or linguistics to gain additional expertise related to cognitive and computational neuroscience. ..
  72. Motor Unit Activity and Force Steadiness Changes w Aging
    Lisa Griffin; Fiscal Year: 2007
    ..This elucidation of the neuromuscular mechanisms that enable hand steadiness will provide the foundation for the design of advanced rehabilitation systems. ..
  73. ANGER, SYMPTOM SPECIFIC REACTIVITY AND CHRONIC PAIN
    John Burns; Fiscal Year: 2002
    ..Documenting a link between anger and LP reactivity will give empirical justification for targeting problematic anger among CLPB patients, and will provide principles on which to found new intervention strategies. ..