Genomes and Genes
Summary: Force exerted when gripping or grasping.
Publications287 found, 100 shown here
- Midlife hand grip strength as a predictor of old age disabilityT Rantanen
Epidemiology, Demography and Biometry Program, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA
JAMA 281:558-60. 1999..Poor muscle strength, functional limitations, and disability often coexist, but whether muscle strength during midlife predicts old age functional ability is not known...
- Objectively measured physical capability levels and mortality: systematic review and meta-analysisRachel Cooper
MRC Unit for Lifelong Health and Ageing and Division of Population Health, University College London, London WC1B 5JU
BMJ 341:c4467. 2010....
- Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopeniaFulvio Lauretani
Geriatric Department, Italian National Insitute of Research and Care on Aging, Florence, Italy
J Appl Physiol 95:1851-60. 2003..The findings of the study lay the basis for a cost-effective, clinical marker of sarcopenia based on a measure of isometric handgrip strength. Our findings should be verified in a longitudinal study...
- Objective measures of physical capability and subsequent health: a systematic reviewRachel Cooper
MRC Unit for Lifelong Health and Ageing, Division of Population Health, University College London, London, UK
Age Ageing 40:14-23. 2011....
- A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approachHelen C Roberts
Academic Geriatric Medicine, University of Southampton, UK
Age Ageing 40:423-9. 2011..Grip strength is recommended as a good simple measure of muscle strength when 'measured in standard conditions'. However, standard conditions remain to be defined...
- Sarcopenia and mortality risk in frail older persons aged 80 years and older: results from ilSIRENTE studyFrancesco Landi
Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
Age Ageing 42:203-9. 2013..sarcopenia has been indicated as a reliable marker of frailty and poor prognosis among the oldest individuals. We evaluated the impact of sarcopenia on the risk of all-cause death in a population of frail older persons living in community...
- Coding and use of tactile signals from the fingertips in object manipulation tasksRoland S Johansson
Physiology Section, Department of Integrative Medical Biology, Umea University, SE 901 87 Umea, Sweden
Nat Rev Neurosci 10:345-59. 2009..Analysis of signals in tactile afferent neurons and central processes in humans reveals how contact events are encoded and used to monitor and update task performance...
- Functional magnetic resonance imaging reveals the neural substrates of arm transport and grip formation in reach-to-grasp actions in humansCristiana Cavina-Pratesi
Department of Psychology, Durham University, Durham DH13LE, United Kingdom
J Neurosci 30:10306-23. 2010....
- Decoding complete reach and grasp actions from local primary motor cortex populationsCarlos E Vargas-Irwin
Department of Neuroscience, Brown University, Providence, Rhode Island 02912, USA
J Neurosci 30:9659-69. 2010....
- Neural correlates of outcome after stroke: a cross-sectional fMRI studyN S Ward
Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, UK
Brain 126:1430-48. 2003..These results further our understanding of the recovery process by demonstrating for the first time a clear relationship between task-related activation of the motor system and outcome after stroke...
- Dynapenia and aging: an updateTodd M Manini
Institute on Aging and Department of Aging and Geriatric Research, University of Florida, Gainesville, FL 32611, USA
J Gerontol A Biol Sci Med Sci 67:28-40. 2012..However, these efforts are expected to provide a specific understanding of the role that dynapenia plays in the loss of physical function and increased risk for disability among older adults...
- The impact of supplemental n-3 long chain polyunsaturated fatty acids and dietary antioxidants on physical performance in postmenopausal womenH L Hutchins-Wiese
Center on Aging, MC 5215, University of Connecticut Health Center Farmington, CT 06030 5215, USA
J Nutr Health Aging 17:76-80. 2013..Identify relationships and evaluate effects of long chain polyunsaturated fatty acids (LCPUFA) on frailty and physical performance...
- Low vitamin D status has an adverse influence on bone mass, bone turnover, and muscle strength in Chinese adolescent girlsLeng Huat Foo
Faculty of Veterinary Science, University of Sydney, Sydney 2006, Australia
J Nutr 139:1002-7. 2009..These findings suggest that adequate vitamin D status during adolescence is important for optimizing bone mass, which may lead to higher peak bone mass at maturity. Poor vitamin D status also compromises forearm muscle strength...
- Grip strength, body composition, and mortalityCatharine R Gale
MRC Epidemiology Resource Centre, University of Southampton, Southampton General Hospital, Southampton, UK
Int J Epidemiol 36:228-35. 2007..We investigated the relation between grip strength, body composition, and cause-specific and total mortality in 800 men and women aged 65 and over...
- Grip strength, postural control, and functional leg power in a representative cohort of British men and women: associations with physical activity, health status, and socioeconomic conditionsDiana Kuh
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, 1 19 Torrington Place, London, United Kingdom, WC1E 6BT
J Gerontol A Biol Sci Med Sci 60:224-31. 2005....
- Age-related changes in the neural correlates of motor performanceN S Ward
Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, UK
Brain 126:873-88. 2003..These results support the notion that an adaptable and plastic motor network is able to respond to age-related degenerative changes in order to maintain performance levels...
- Task-dependent modulations of cortical oscillatory activity in human subjects during a bimanual precision grip taskJ M Kilner
Sobell Department of Neurophysiology, Institute of Neurology, Queen Square, London, United Kingdom
Neuroimage 18:67-73. 2003....
- Contributions of descending and ascending pathways to corticomuscular coherence in humansClaire L Witham
Institute of Neuroscience, Newcastle University, Henry Wellcome Building for Neuroecology, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
J Physiol 589:3789-800. 2011..These results confirm the complex nature of corticomuscular coherence with contributions from both descending and ascending pathways...
- Patterns of muscle activity underlying object-specific grasp by the macaque monkeyT Brochier
Sobell Dept of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London WC1N 3BG, UK
J Neurophysiol 92:1770-82. 2004..These results identify the specific patterns of activity required to achieve distinct hand postures for grasping, and they open the way to our understanding of how these patterns are generated by the central motor network...
- Predicting movement from multiunit activityEran Stark
Department of Physiology, Hadassah Medical School, Hebrew University, Jerusalem 91120, Israel
J Neurosci 27:8387-94. 2007....
- Hand strength: normative valuesC A Crosby
Pennsylvania Hand Center, Bryn Mawr 19010
J Hand Surg Am 19:665-70. 1994We studied normal hand strength and the difference between dominant and nondominant hands. Two hundred fourteen volunteers were tested with a calibrated Jamar dynamometer at all five levels...
- Absolute strength and loss of strength as predictors of mobility decline in older adults: the InCHIANTI studyGregory E Hicks
Department of Physical Therapy, University of Delaware, Newark, DE 19716, USA
J Gerontol A Biol Sci Med Sci 67:66-73. 2012..This study sought to identify sex-specific cutpoints for muscle strength and power (at one time point) and 3-year changes in strength and power that would maximize prediction of 3-year mobility decline...
- Decoding natural grasp types from human ECoGTobias Pistohl
Bernstein Center Freiburg BCF, 79104 Freiburg, Germany
Neuroimage 59:248-60. 2012..We conclude that ECoG signals are promising candidates for BMIs that include the restoration of grasping movements...
- Physical activity across adulthood and physical performance in midlife: findings from a British birth cohortRachel Cooper
MRC Unit for Lifelong Health and Ageing, Division of Population Health, University College London, United Kingdom
Am J Prev Med 41:376-84. 2011..It is unclear whether the benefits of physical activity accumulate across life or whether there are sensitive periods when physical activity is more influential...
- Delayed visual feedback affects both manual tracking and grip force control when transporting a handheld objectFabrice R Sarlegna
Institute of Movement Sciences, Centre National de la Recherche Scientifique and Université de la Méditerranée, Marseille, France
J Neurophysiol 104:641-53. 2010..Overall, our findings support the idea that visual feedback of object motion can influence the predictive control of grip force even when the object is grasped...
- Skeletal muscle strength as a predictor of all-cause mortality in healthy menE Jeffrey Metter
National Institute on Aging, Gerontology Research Center, Baltimore, Maryland 21224, USA
J Gerontol A Biol Sci Med Sci 57:B359-65. 2002..Strength and rate of change in strength contribute to the impact of sarcopenia on mortality. Although muscle mass and physical activity are important, they do not completely account for the impact of strength and changes in strength...
- Cortical connections of the macaque anterior intraparietal (AIP) areaElena Borra
Dipartimento di Neuroscienze, Sezione di Fisiologia, Universita di Parma, I43100 Parma, Italy
Cereb Cortex 18:1094-111. 2008..Thus, AIP could represent a crucial node in a cortical circuit in which hand-related sensory and motor signals gain access to representations of object identity for tactile object recognition...
- The cognitive neuroscience of prehension: recent developmentsScott T Grafton
Department of Psychology, SAGE Center for the Study of Mind, University of California at Santa Barbara, Santa Barbara, CA 93106, USA
Exp Brain Res 204:475-91. 2010..The review ends with a consideration about how prehension fits within larger action repertoires that solve more complex goals and the possible cortical architectures needed to organize these actions...
- Elbow position affects handgrip strength in adolescents: validity and reliability of Jamar, DynEx, and TKK dynamometersVanesa España-Romero
Department of Physiology, School of Medicine, University of Granada, Granada, Spain
J Strength Cond Res 24:272-7. 2010..The present study provides useful and relevant information indicating which elbow position, and which type of dynamometer, yield maximal handgrip strength in adolescents...
- Hand-grip dynamometry predicts future outcomes in aging adultsRichard W Bohannon
Department of Physical Therapy, Neag School of Education, University of Connecticut, Storrs, CT 06269 2101, USA
J Geriatr Phys Ther 31:3-10. 2008..One use of clinical measures is the prediction of future outcomes. The purpose of this systematic review was to summarize the literature addressing the value of grip strength as a predictor of important outcomes...
- Disconnecting force from money: effects of basal ganglia damage on incentive motivationLiane Schmidt
Laboratoire INSERM U610, Institut Fédératif de Recherches en Neurosciences, Universite Pierre et Marie Curie Paris 6, Site Pitié Salpêtrière, F 75013 Paris, France
Brain 131:1303-10. 2008..We conclude that bilateral striato-pallidal damage specifically disconnects motor output from affective evaluation of potential rewards...
- Anticipatory planning and control of grasp positions and forces for dexterous two-digit manipulationQiushi Fu
Department of Kinesiology, Arizona State University, Tempe, Arizona 85287 0404, USA
J Neurosci 30:9117-26. 2010..These results are discussed in the context of motor equivalence and sensorimotor integration of grasp kinematics and kinetics...
- Neural correlates of age-related changes in cortical neurophysiologyP Talelli
Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College, London, UK
Neuroimage 40:1772-81. 2008....
- The relationship between brain activity and peak grip force is modulated by corticospinal system integrity after subcortical strokeNick S Ward
Wellcome Department of Imaging Neuroscience, and Department of Brain Repair and Rehabilitation, Institute of Neurology, University College London, London, UK
Eur J Neurosci 25:1865-73. 2007..These findings suggest that the premotor cortices might play a new and functionally relevant role in controlling force production in patients with more severe corticospinal system disruption...
- Handgrip strength as a predictor of functional, psychological and social health. A prospective population-based study among the oldest oldDiana G Taekema
Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands
Age Ageing 39:331-7. 2010..Muscle strength measurements could be useful as part of a clinical evaluation of oldest old patients to determine who are most at risk of accelerated decline in the near future...
- Sarcopenia in elderly men and women: the Rancho Bernardo studyEdward M Castillo
Joint Doctoral Program, Public Health, San Diego State University University of California, San Diego, La Jolla, California, USA
Am J Prev Med 25:226-31. 2003..Sarcopenia risk factors are poorly understood...
- Control strategies in object manipulation tasksJ Randall Flanagan
Department of Psychology, Centre for Neuroscience Studies, Queen s University, Kingston, ON, K7L 3N6, Canada
Curr Opin Neurobiol 16:650-9. 2006..Successful manipulation requires the ability both to predict the motor commands required to grasp, lift, and move objects and to predict the sensory events that arise as a consequence of these commands...
- Human cortical control of hand movements: parietofrontal networks for reaching, grasping, and pointingFlavia Filimon
Max Planck Institute for Human Development, Berlin, Germany
Neuroscientist 16:388-407. 2010..The available evidence supports a cortical organization along gradients of sensory (visual to somatosensory) and effector (eye to hand) preferences...
- Functional properties of grasping-related neurons in the ventral premotor area F5 of the macaque monkeyVassilis Raos
Dipartimento di Neuroscienze, Sezione di Fisiologia, Universita di Parma, Parma, Italy
J Neurophysiol 95:709-29. 2006....
- The role of synchrony and oscillations in the motor outputS N Baker
Sobell Department of Neurophysiology, Institute of Neurology, Queen Square, London, WC1N 3BG, UK
Exp Brain Res 128:109-17. 1999..A speculative hypothesis is presented on the role of synchronous oscillations in the motor system, which is consistent with experimental observations to date...
- Motor assessment using the NIH ToolboxDavid B Reuben
Division of Geriatrics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
Neurology 80:S65-75. 2013....
- Age trajectories of grip strength: cross-sectional and longitudinal data among 8,342 Danes aged 46 to 102Henrik Frederiksen
Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark
Ann Epidemiol 16:554-62. 2006..The purpose is to study the age trajectory of hand-grip strength after the age of 45 years...
- Performance measures predict onset of activity of daily living difficulty in community-dwelling older adultsWen Ni Wennie Huang
Department of Physical Therapy, I Shou University, Kaohsiung, Taiwan
J Am Geriatr Soc 58:844-52. 2010..To assess the predictive value of five performance-based measures for the onset of difficulty in activities of daily living (ADLs)...
- Decoding 3D reach and grasp from hybrid signals in motor and premotor cortices: spikes, multiunit activity, and local field potentialsArjun K Bansal
Department of Neuroscience, Brown University, Providence, RI, USA
J Neurophysiol 107:1337-55. 2012..For BCIs, our results indicate that neuronal ensemble spiking is the preferred signal for decoding, while LFPs and combined signals from PMv and MI can add robustness to BCI control...
- Simultaneous recording of macaque premotor and primary motor cortex neuronal populations reveals different functional contributions to visuomotor graspM A Umilta
Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, UK
J Neurophysiol 98:488-501. 2007....
- What does the brain do when you fake it? An FMRI study of pantomimed and real graspingG Kroliczak
Canadian Institutes of Health Research Group in Action and Perception, Department of Psychology, University of Western Ontario, London, Canada
J Neurophysiol 97:2410-22. 2007..Moreover, pantomimed grasping may not tap object-related areas within the ventral stream, but rather may rely on mechanisms within the right hemisphere that are recruited by artificial and less practiced actions...
- Tie my hands, tie my eyesEttore Ambrosini
Laboratory of Neuropsychology and Cognitive Neuroscience, University G D Annunzio, Chieti, Italy
J Exp Psychol Hum Percept Perform 38:263-6. 2012..This suggests, for the first time, that actions are observed best when we are actually in the position to perform them...
- Sarcopenia and osteopenia among 70-80-year-old home-dwelling Finnish women: prevalence and association with functional performanceR Patil
The UKK Institute for Health Promotion Research, PO Box 30, 33501 Tampere, Finland
Osteoporos Int 24:787-96. 2013..Muscle mass and derived indices of sarcopenia were not significantly related to measures of functional ability...
- Force-independent distribution of correlated neural inputs to hand muscles during three-digit graspingBrach Poston
Department of Kinesiology, Arizona State University, Tempe, Arizona 85287 0404, USA
J Neurophysiol 104:1141-54. 2010..0039). These findings indicate that the distribution of neural drive to multiple hand muscles is force independent and may reflect the anatomical properties or functional roles of hand muscle groups...
- Memory mechanisms in graspingConstanze Hesse
Experimental Psychology, University of Giessen, Germany
Neuropsychologia 47:1532-45. 2009..Therefore, the authors propose that grasping after a delay is guided by classic memory mechanisms and that this is reflected in an increasing maximum grip aperture in grasping...
- Where one hand meets the other: limb-specific and action-dependent movement plans decoded from preparatory signals in single human frontoparietal brain areasJason P Gallivan
Brain and Mind Institute, Natural Sciences Centre and Department of Psychology, University of Western Ontario, London, Ontario, Canada
J Neurosci 33:1991-2008. 2013....
- Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS)Harnish P Patel
MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK
Age Ageing 42:378-84. 2013..The aim of this study was to describe the prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) consensus definition...
- Subthalamic nucleus activity optimizes maximal effort motor responses in Parkinson's diseaseAnam Anzak
Functional Neurosurgery Experimental Neurology Group, Department of Clinical Neurology, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK
Brain 135:2766-78. 2012....
- Getting a grip on numbers: numerical magnitude priming in object graspingOliver Lindemann
Nijmegen Institute for Cognition and Information, Radboud University Nijmegen, The Netherlands
J Exp Psychol Hum Percept Perform 33:1400-9. 2007..The data indicate a priming of size-related motor features by numerals and support the idea that representations of numbers and actions share common cognitive codes within a generalized magnitude system...
- The cortical control of visually guided graspingUmberto Castiello
Dipartimento di Psicologia Generale Università di Padova, Padova, Italy
Neuroscientist 14:157-70. 2008..It compares and summarizes results from behavioral neuroscience, electrophysiology, and neuroimaging to provide a detailed description of the neural circuits that facilitate the formation of grip patterns in human and nonhuman primates...
- Developmental origins of midlife grip strength: findings from a birth cohort studyDiana Kuh
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, UK
J Gerontol A Biol Sci Med Sci 61:702-6. 2006..We tested whether prepubertal growth, pubertal growth, or the development of motor and cognitive capabilities was associated with midlife muscle strength independently of other determinants of grip strength...
- Hand-grip strength cut points to screen older persons at risk for mobility limitationJanne Sallinen
Gerontology Research Centre, Department of Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland
J Am Geriatr Soc 58:1721-6. 2010..To determine optimal hand-grip strength cut points for likelihood of mobility limitation in older people and to study whether these cut points differ according to body mass index (BMI)...
- Cutpoints for low appendicular lean mass that identify older adults with clinically significant weaknessPeggy M Cawthon
California Pacific Medical Center Research Institute, 185 Berry Street, Suite 5700, San Francisco, CA 94107 1762
J Gerontol A Biol Sci Med Sci 69:567-75. 2014....
- Motor control strategies in a continuous task spaceChristoph Schütz
Faculty of Psychology and Sport Sciences, Bielefeld University, Bielefeld, Germany
Motor Control 15:321-41. 2011..Experimental results further revealed a work range restriction effect, which was reproduced for the dominant and the nondominant hand...
- Ventral premotor and inferior parietal cortices make distinct contribution to action organization and intention understandingLuca Bonini
Dipartimento di Neuroscienze, Universita degli Studi di Parma, Parma, Italy
Cereb Cortex 20:1372-85. 2010..Furthermore, the similarities between MNs properties of the 2 areas indicate that they constitute a functional circuit underlying others' intention understanding...
- Clinical burden of erosive hand osteoarthritis and its relationship to nodesJ Bijsterbosch
Leiden University Medical Centre, Department of Rheumatology, C1 R, P O Box 9600, 2300 RC Leiden, The Netherlands
Ann Rheum Dis 69:1784-8. 2010..To describe the clinical burden of erosive osteoarthritis (EOA) of the hand in terms of pain, functioning and health-related quality of life (HRQL) and its relationship to nodal osteoarthritis (OA)...
- Heterogeneity in rate of decline in grip, hip, and knee strength and the risk of all-cause mortality: the Women's Health and Aging Study IIQian Li Xue
Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
J Am Geriatr Soc 58:2076-84. 2010..To assess the relationship between rate of change in muscle strength and all-cause mortality...
- Reference equations for the performance of healthy adults on field walking testsVictor Zuniga Dourado
Universidade Federal de Sao Paulo, Santos, SP, Brasil
J Bras Pneumol 37:607-14. 2011..To develop regression equations for predicting six-minute and incremental shuttle walk distances (6MWD and ISWD, respectively), based on demographic characteristics, anthropometric variables, and grip strength...
- Force coordination in static manipulation tasks performed using standard and non-standard grasping techniquesPaulo B de Freitas
Human Performance Lab, Department of Health, Nutrition, and Exercise Sciences, University of Delaware, 547 South College Avenue, Newark, DE 19716, USA
Exp Brain Res 194:605-18. 2009....
- Association between lean mass and handgrip strength with bone mineral density in physically active postmenopausal womenRosangela Villa Marin
Physical Fitness Research Center of São Caetano do Sul CELAFISCS, Sao Paulo, Brazil
J Clin Densitom 13:96-101. 2010..Our results suggest that strategies aiming to improve muscle strength and lean mass must contribute to the bone health of physically active postmenopausal women...
- Validity and reproducibility of hand-held dynamometry in children aged 4-11 yearsWilleke A van den Beld
Department of Rehabilitation Medicine and Interdisciplinary Child Neurology Centre, University Medical Centre, Nijmegen St Radboud, Nijmegen, The Netherlands
J Rehabil Med 38:57-64. 2006..To evaluate validity and reproducibility of hand-held dynamometry in 11 different muscle groups in children...
- Planning of visually guided reach-to-grasp movements: inference from reaction time and contingent negative variation (CNV)Manuel Zaepffel
Institut de Neurosciences Cognitives de la Mediterranee, UMR 6193, CNRS, Universite de la Mediterranee, Marseille, France
Psychophysiology 49:17-30. 2012..Finally, we outline the composite nature of the lCNV that might reflect both high- and low-level planning processes...
- Decoding of grasping information from neural signals recorded using peripheral intrafascicular interfacesSilvestro Micera
BioRobotics Institute, Scuola Superiore Sant Anna, Pisa, Italy
J Neuroeng Rehabil 8:53. 2011..This goal can be achieved with several approaches and among them, the use of implantable interfaces connected with the peripheral nervous system, namely intrafascicular electrodes, is considered particularly interesting...
- Causal connectivity between the human anterior intraparietal area and premotor cortex during graspMarco Davare
Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK
Curr Biol 20:176-81. 2010..These findings suggest that grasp-related and muscle-specific PMv-M1 interactions are driven by information about object properties provided by AIP...
- Synchronization in monkey motor cortex during a precision grip task. II. effect of oscillatory activity on corticospinal outputStuart N Baker
Sobell Department of Neurophysiology, Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom
J Neurophysiol 89:1941-53. 2003..The oscillations will therefore be effectively transmitted to spinal motoneurons, and this has important consequences for the possible role of oscillations in motor control of the hand...
- Ipsilateral motor dysfunction from unilateral stroke: implications for the functional neuroanatomy of hemiparesisO Noskin
Neurological Institute of New York, Columbia University Medical Center, New York, NY 10032, USA
J Neurol Neurosurg Psychiatry 79:401-6. 2008..By tracking motor function of both hands beginning in the acute stroke period in patients with cortical versus subcortical lesions, we sought to understand the functional anatomy of the ipsilateral deficit...
- Hand grip strength: outcome predictor and marker of nutritional statusKristina Norman
Department of Gastroenterology, Hepatology and Endocrinology, Charite University Medicine Berlin, Berlin, Germany
Clin Nutr 30:135-42. 2011..This review outlines the prognostic relevance of grip strength in various clinical and epidemiologic settings and investigates its suitability as marker of nutritional status in cross-sectional as well as intervention studies...
- Testosterone, physical activity, and somatic outcomes among Filipino malesLee T Gettler
Department of Anthropology, Northwestern University, Evanston, IL 60208, USA
Am J Phys Anthropol 142:590-9. 2010....
- Attenuation of corticomuscular coherence with additional motor or non-motor taskAshley N Johnson
School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA
Clin Neurophysiol 122:356-63. 2011..Additionally, we examined the potential associations between corticomuscular coherence and fine motor performance...
- Association between functional capacity tests and fractures: an eight-year prospective population-based cohort studyM Karkkainen
Bone and Cartilage Research Unit, University of Kuopio, P O Box 1627, MediTeknia Building, 70211 Kuopio, Finland
Osteoporos Int 19:1203-10. 2008..The standing-on-one-foot and grip strength tests and a question about self-assessed ability to move can be used to identify women with a high risk of suffering a fracture...
- Effects of object shape and visual feedback on hand configuration during graspingLuis F Schettino
Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
Exp Brain Res 151:158-66. 2003....
- Functional properties of grasping-related neurons in the dorsal premotor area F2 of the macaque monkeyVassilis Raos
Dipartimento di Neuroscienze, Sezione di Fisiologia, Universita di Parma, 43100 Parma, Italy
J Neurophysiol 92:1990-2002. 2004..These results indicate an important role of F2 in the control of goal-related hand movements...
- Grip strength predicts cause-specific mortality in middle-aged and elderly personsHideo Sasaki
Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan
Am J Med 120:337-42. 2007..Handgrip strength is a simple measurement used to estimate overall muscle strength but might also serve as a predictor of health-related prognosis. We investigated grip strength-mortality association in a longitudinal study...
- Walking speed as a good predictor for the onset of functional dependence in a Japanese rural community populationS Shinkai
Department of Community Health, Tokyo Metropolitan Institute of Gerontology, Japan
Age Ageing 29:441-6. 2000..to investigate and compare the predictive values of four physical performance measures for the onset of functional dependence in older Japanese people living at home...
- Task goal and grip force dynamicsKimberlee Jordan
Department of Kinesiology, 266 Recreation Building, The Pennsylvania State University, University Park, PA 16802, USA
Exp Brain Res 156:451-7. 2004..Theorizing about the organization of isometric force output should include the effects of task goals as well as the level of force per se...
- Grasping the intentions of others with one's own mirror neuron systemMarco Iacoboni
Ahmanson Lovelace Brain Mapping Center, Neuropsychiatric Institute, David Geffen School of Medicine, University of California, Los Angeles, California, USA
PLoS Biol 3:e79. 2005..To ascribe an intention is to infer a forthcoming new goal, and this is an operation that the motor system does automatically...
- How objects are grasped: the interplay between affordances and end-goalsLuisa Sartori
Dipartimento di Psicologia Generale, Universita di Padova, Padova, Italy
PLoS ONE 6:e25203. 2011..Little is known about how the placement of individual fingers on objects is affected by the end-goal of the action...
- Cortical excitability changes following grasping exercise augmented with electrical stimulationGergely I Barsi
Center for Sensory Motor Interaction, Department of Health Science and Technology, Aalborg University, Fredrik Bajers Vej 7 D 3, 9220, Aalborg, Denmark
Exp Brain Res 191:57-66. 2008....
- How predictive is grip force control in the complete absence of somatosensory feedback?Dennis A Nowak
Department of Neurology and Clinical Neurophysiology, Academic Hospital Munchen Bogenhausen, Technical University of Munich, Englschalkingerstrasse 77, D 81925 Munich, Germany
Brain 127:182-92. 2004..We conclude that predictive grip force control requires at least intermittent sensory feedback to signal the effectiveness of descending motor commands and to update internal models...
- Finger interaction during accurate multi-finger force production tasks in young and elderly personsMinoru Shinohara
Department of Integrative Physiology, University of Colorado, CO 80309, Boulder, USA
Exp Brain Res 156:282-92. 2004..This general result underscores the importance of efforts to analyze motor coordination using control rather than performance variables...
- Internal models underlying grasp can be additively combinedPaul R Davidson
Sobell Dept of Motor Neuroscience, Institute of Neurology, University College London, Queen Square, WC1 N 3BG, London, UK
Exp Brain Res 155:334-40. 2004..Results show that subjects can additively combine internal models of object dynamics but the sum is biased by a default estimate of the object's weight...
- Is grip strength associated with health-related quality of life? Findings from the Hertfordshire Cohort StudyAvan Aihie Sayer
MRC Epidemiology Resource Centre, University of Southampton, Southampton, UK
Age Ageing 35:409-15. 2006..to investigate the relationship between grip strength and health-related quality of life (HRQoL)...
- Get aroused and be stronger: emotional facilitation of physical effort in the human brainLiane Schmidt
Institut du Cerveau et de la Moëlle épinière ICM, INSERM UMRS 975, Paris, France
J Neurosci 29:9450-7. 2009..We suggest that this region, by driving the motor cortex, constitutes a brain pathway that allows emotional arousal to facilitate physical effort...
- Does the intention to communicate affect action kinematics?Luisa Sartori
Dipartimento di Psicologia Generale, Universita di Padova, Italy
Conscious Cogn 18:766-72. 2009..Results are discussed in terms of cognitive pragmatics and current knowledge on how social behavior shapes action kinematics...
- The effect of obstacle position on reach-to-grasp movementsM Mon-Williams
School of Psychology, University of St Andrews, St Andrews, Fife, KY16 9JU, Scotland, UK
Exp Brain Res 137:497-501. 2001..These results show that the anticipated likelihood of a collision with potential obstacles affects the planning of movement duration and maximum grip aperture in prehension...
- Is there an association between serum 25-hydroxyvitamin D concentration and muscle strength among older women? Results from baseline assessment of the EPIDOS studyC Annweiler
Department of Geriatrics, Angers University Hospital, France
J Nutr Health Aging 13:90-5. 2009....
- Epidemiology of balance and dizziness in a national population: findings from the English Longitudinal Study of AgeingKara N Stevens
Peninsula Medical School, Epidemiology and Public Health Group, UK
Age Ageing 37:300-5. 2008..to identify socio-economic, behavioural and disease status risks for impaired balance or self-reported dizziness in older people from a large population-based study...
- Visually guided grasping produces fMRI activation in dorsal but not ventral stream brain areasJody C Culham
Department of Psychology, University of Western Ontario, London, Ontario, N6A 5C2, Canada
Exp Brain Res 153:180-9. 2003..These results suggest that dorsal areas, including AIP, but not ventral areas such as LOC, play a fundamental role in computing object properties during grasping...
- Age-dependent changes in the neural correlates of force modulation: an fMRI studyNick S Ward
Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
Neurobiol Aging 29:1434-46. 2008..These results indicate that a reduced ability to modulate activity in appropriate motor networks when required may contribute to age-related decline in motor performance...
- Gamma-range corticomuscular coherence during dynamic force outputWolfgang Omlor
Neurological Clinic, Albert Ludwigs University, Breisacher Strasse 64, 79106 Freiburg, Germany
Neuroimage 34:1191-8. 2007....
- The cortical motor systemG Rizzolatti
Istituto di Fisiologia Umana, Universita di Parma, Via Volturno 39, I43100 Parma, Italy
Neuron 31:889-901. 2001..We submit that generating internal representations of actions is central to cortical motor function. External contingencies and motivational factors determine then whether these action representations are transformed into actual actions...
- The impact of stroke on the performance of grasping: usefulness of kinetic and kinematic motion analysisDennis A Nowak
Department of Neurology, University of Cologne, Cologne, Germany
Neurosci Biobehav Rev 32:1439-50. 2008....
- Exposure-dependent increases in IL-1beta, substance P, CTGF, and tendinosis in flexor digitorum tendons with upper extremity repetitive strain injuryJane M Fedorczyk
Department of Physical Therapy and Rehabilitation Sciences, Drexel University, 245 North 15th Street, MS502, Philadelphia, Pennsylvania 19102, USA
J Orthop Res 28:298-307. 2010....
- Objects automatically potentiate action: an fMRI study of implicit processingJ Grezes
Wellcome Department of Imaging Neuroscience, University College London, 12 Queen Square, London WC1N 3BG, London, UK
Eur J Neurosci 17:2735-40. 2003....
- A comparison of frailty indexes for the prediction of falls, disability, fractures, and mortality in older menKristine E Ensrud
Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
J Am Geriatr Soc 57:492-8. 2009....
- Chronic inflammation and the effect of IGF-I on muscle strength and power in older personsMichelangela Barbieri
Department of Geriatric Medicine and Metabolic Diseases, II University of Naples, Italy
Am J Physiol Endocrinol Metab 284:E481-7. 2003..This mechanism may explain why IL-6 is a strong risk factor for disability...
- Surgical Simulations to Optimize the Treatment of Wrist OsteoarthritisJennifer A Nichols; Fiscal Year: 2013..In Am 3, post-operative wrist and hand strength will be measured in vivo, and these data will be used in musculoskeletal computer models to evaluate how ..
- Quantifying the Recovery Response and Role of Hand Strength During Ladder FallsNa Jin Seo; Fiscal Year: 2013..quantitative knowledge on biomechanical causes and recovery response from a ladder fall as well as the role of hand strength in recovering from a ladder slip and misstep...
- Nerve Stimulation to Improve Hand Weakness in StrokeADRIANA CONFORTO; Fiscal Year: 2004..collaboration for future studies regarding: effectiveness of electrical stimulation and training in improving hand strength and decreasing motor disability in chronic stroke patients; prognostic factors for response to rehabilitation ..
- EFFECTS OF MOVEMENT CONTEXT ON HEMIPARETIC GRASPING EARLY AFTER STROKECatherine E Lang; Fiscal Year: 2010..More successful performance during rehabilitation may also lead to more practice and use outside of rehabilitation. ..
- Control of Finger Movements after StrokeCATHERINE LANG; Fiscal Year: 2003..Results from these experiments may assist rehabilitation professionals in designing and implementing rehabilitation strategies to improve hand function in people after stroke. ..
- fMRI Activity During the Visual Control of ForceDAVID VAILLANCOURT; Fiscal Year: 2004..These findings will have further implications for better understanding the visuomotor control deficits associated with aging, and diseased persons with Parkinson's disease, ataxia, and cerebellar deficits. ..
- Hand Function in Multiple SclerosisSlobodan Jaric; Fiscal Year: 2006....
- VESTIBULOSYMPATHETIC REFLEXES IN HUMANSCHESTER RAY; Fiscal Year: 2001....
- NEURAL MECHANISMS OF CUTANEOUS SPATIAL INTEGRATIONESTHER GARDNER; Fiscal Year: 2008..Principles of sensorimotor integration derived from this research may prove useful for developing better sensory prostheses or robotic manipulators based on biological models of hand function. ..
- Linking motor imagery to motor executionSheng Li; Fiscal Year: 2006..unreadable] [unreadable] [unreadable] [unreadable]..
- NEUROINFORMATICS AND EYE-HAND COORDINATIONESTHER GARDNER; Fiscal Year: 2005....
- Muscle Mechanosensitivity in Heart FailureHolly Middlekauff; Fiscal Year: 2004..After a 4 week conditioning program, which reverses the myopathy of HF, the above testing repeated to determine if the muscle mechanoreceptor sensitization is reversible. ..
- Bilingual Speech SegmentationDaniel Weiss; Fiscal Year: 2006..In sum, the proposed research will fill gaps in current knowledge regarding both bilingual language acquisition as well as statistical learning. ..
- Linkage Studies of Quantitative Ocular TraitsBarbara Klein; Fiscal Year: 2006..Subsequent follow-up with fine mapping of areas of interest in the genome is planned. ..
- OptiPush Wheelchair Training SystemW Richter; Fiscal Year: 2006..Pre- and post-training evaluations will include exercise capacity, propulsion strength, propulsion efficiency and propulsion biomechanics testing. [unreadable] [unreadable]..
- Massaging Preterm Infants Enhances GrowthTiffany Field; Fiscal Year: 2006..abstract_text> ..
- Antipsychotics: Temporal Effects on Cognitive FunctionAlvin Terry; Fiscal Year: 2006..unreadable] [unreadable]..
- ErgoChair Smart Manual WheelchairW Richter; Fiscal Year: 2008..This project will develop innovative technology that will dramatically improve the ergonomics of wheelchair transfers and lifting tasks. [unreadable] [unreadable]..
- Risk Factors and the Neurobiologic Substrate of FrailtyAron Buchman; Fiscal Year: 2009..abstract_text> ..
- TESTOSTERONE FOR PREVENTION OF FRACTURE IN MENAnne Kenny; Fiscal Year: 2005....
- Neurohormonal Effects of Massage TherapyTiffany Field; Fiscal Year: 2007..The K05 would allow me to increase my research time including being mentored and mentoring students from 25 to 75% time. [unreadable] [unreadable] [unreadable]..
- Prenatal Depression and a Yoga InterventionTiffany M Field; Fiscal Year: 2010..We would expect that yoga would decrease depression, increase vagal activity, decrease cortisol and increase gestational age (decrease prematurity). ..
- THE SLEEP HEART HEALTH STUDYAnne Newman; Fiscal Year: 2007..Accomplishing these goals will provide important information concerning the public health impact of SDB. [unreadable] [unreadable]..
- Cotinine for Cognitive Impairment in Neurological and Neuropsychiatric DisordersAlvin V Terry; Fiscal Year: 2010..The partly translational design of the study will provide results leading to eventual clinical trials with cotinine or a relevant analog. ..
- Neuromuscular Fatigue in Older AdultsSandra Hunter; Fiscal Year: 2008..unreadable] [unreadable]..
- Detecting Endothelial Dysfunction in Renal FailureJulian Stewart; Fiscal Year: 2007..These data will form the basis of future noninvasive prognostic testing and treatment of patients at risk for ECD and can provide a means to follow treatment modalities. [unreadable] [unreadable] [unreadable]..
- BENZODIAZEPINE USE AND RISK OF DISABILITY IN THE ELDERLYShelly Gray; Fiscal Year: 2003....
- Circulatory Dysfunction in Chronic Fatigue SyndromeJulian Stewart; Fiscal Year: 2004....
- Spatial Attention in Visuomotor ProcessingTODD HANDY; Fiscal Year: 2005....
- Family Clustering of Incidence & Progression of CataractBarbara Klein; Fiscal Year: 2003..We currently have no funds to support the proposed analyses. We believe this project offers the possibility of examining important hypotheses in a large group of families in a population-based framework. ..
- Task Dependence of Muscle Fatigue in Older AdultsSandra Hunter; Fiscal Year: 2005..These preliminary findings will form the foundation for an RO 1 application that will further explore the mechanisms and task dependency of muscle fatigue in older adults. ..
- PROGRESSION OF NUCLEAR DENSITY OVER A 10-YEAR INTERVALBarbara Klein; Fiscal Year: 2002....
- EPIDEMIOLOGY OF CORONARY CALCIFICATION IN THE ELDERLYAnne Newman; Fiscal Year: 2005..abstract_text> ..
- IGF-I/ALS TrialEric Sorenson; Fiscal Year: 2007..The preliminary data from our prior trial allows design of a phase III treatment trial that will yield a definitive result about the treatment effect of IGF-I. ..
- ORGANIZATION AND CONTROL OF MOVEMENTJOHN SOECHTING; Fiscal Year: 2007..Providing sensory feedback would clearly enhance the efficacy of brain-machine interfaces and these results will provide new information about the normal utilization of sensory inflow in the control of movements. ..
- Knee Disorders and Occupational Biomechanical RisksBryan Buchholz; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- The Family Blood Pressure Program (SAPPHIRe Network)JESS CURB; Fiscal Year: 2007..unreadable] (End of Abstract) [unreadable] [unreadable]..
- Oxidative Stress and Vascular Function in Chronic Kidney DiseaseDavid Edwards; Fiscal Year: 2008..Understanding these mechanisms may aid in the evaluation of therapies aimed at improving vascular function in chronic kidney disease. [unreadable] [unreadable] [unreadable]..
- TESTING THE EXERCISE PLUS PROGRAM FOLLOWING HIP FRACTUREBarbara Resnick; Fiscal Year: 2002....
- DEVELOPMENT OF FUNCTIONAL LIMITATIONS IN THE BUILT ENVIRONMENT OF MID-AGED WOMENKristin Tomey; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- DEMENTIA IN SWEDISH TWINSMargaret Gatz; Fiscal Year: 2002..Different diagnostic criteria will be compared. Quantitative indices will be derived from neuropsychological scores and from neuroimaging data subjected to quantitative mapping. ..
- Dementia in Swedish Twins Data ArchivingMargaret Gatz; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- Mechanisms of Atherosclerosis and CVD in HIV+ WomenRobert Kaplan; Fiscal Year: 2009..This investigation will have major implications for the development of strategies to predict, prevent, or reverse atherosclerosis in HIV- infected women. ..
- Magnetic Resonance in Peripheral Arterial DiseaseMary Mcgrae McDermott; Fiscal Year: 2010..This knowledge, in subsequent studies, is expected to lead to new therapies for PAD-related functional impairment and functional decline. ..
- Venous Hemodynamic Function in Older Hypertensive AdultsWILLIAM FARQUHAR; Fiscal Year: 2006....
- Phase II Therapeutic Trial of Mexiletine Richard J Barohn; Fiscal Year: 2010..These secondary measures will be quantified by lndividual Neuromuscular Quality of Life (INQOL), SF-36 (adults), SF-10 (children), grip myotonia, physical exam, and electrophysiological testing, respectively. ..
- NIH OSTEOPOROSIS & RELATED BONE DISEASES RESOURCE CENTERBess Dawson Hughes; Fiscal Year: 2002..Specific efforts include supporting the National Osteoporosis Data Group, collecting and disseminating definitive statistics on bone diseases and on conditions co-morbid with osteoporosis, and preparing summary reports. ..
- POSTMENOPAUSAL HORMONAL REPLACEMENT THERAPYWanpen Vongpatanasin; Fiscal Year: 2006..The long-term goal of her work would be the discovery the most effective estrogen preparation that can prevent or treat hypertension in women after menopause. ..
- Genomic Characterization in Depression and Suicide.Etienne Sibille; Fiscal Year: 2007..The training program proposes formal courses, supervised training and frequent interactions with several research groups involved in pioneering aspects of genomic research in mood disorders. [unreadable] [unreadable]..
- Cognitive-Emotional Integration in Adulthood and AgingMark Lumley; Fiscal Year: 2007..abstract_text> ..
- A Preclinical Model of Adolescent Toluene Abuse in RatsScott Bowen; Fiscal Year: 2005..The model also has the potential to assist in devising effective treatments and prevention strategies for adolescent inhalant abuse. ..
- Mechanisms of Disability in Peripheral Arterial DiseaseMary McDermott; Fiscal Year: 2005..Results will be used to develop interventions designed to improve lower extremity functioning and prevent functional decline in persons with PAD. ..
- Self-administration of abused inhalants in miceScott Bowen; Fiscal Year: 2004....
- Developing an Instrument to Measure Keyboarding StyleNancy Baker; Fiscal Year: 2006..This information will be integrated into the final tool, the PECKS. The PECKS can then be used to identify an individual who have keyboarding...styles that have been associated with MSD-UE. ..
- ADJUNCT VITAMIN A THERAPY FOR TUBERCULOSIS AND HIV/AIDSRichard Semba; Fiscal Year: 2005....
- Estimating Joint Impedance from the Surface EMGEDWARD CLANCY; Fiscal Year: 2004..abstract_text> ..
- Task Practice Schedules to Enhance Recovery after StrokeNicolas Schweighofer; Fiscal Year: 2006..The hypothesis is that subjects with mild deficits benefit most from expanded variable practice, whereas subjects with moderate deficits benefit most from massed practice schedules. [unreadable] [unreadable]..
- COMMUNITY EPIDEMIOLOGIC STUDY OF CAREGIVING AND HEALTHLiesi Hebert; Fiscal Year: 2004..Factors found to minimize negative health effects will provide potential interventions to minimize stress and maintain the health of older caregivers, and thereby minimize the social and economic impacts of caregiving. ..
- Development of Eye-Hand Coordination in Infant ReachingDaniela Corbetta; Fiscal Year: 2004..From these data, hypotheses regarding the processes underlying the development of infants' eye-hand coordination in the 1st year will be assessed. ..
- fMRI and TMS of Motor Recovery after Hemiparetic StrokeJudith Schaechter; Fiscal Year: 2007..abstract_text> ..
- Reactive astrocytes from gliotic capsuleJ Marc Simard; Fiscal Year: 2007..unreadable] [unreadable]..
- Regulation of Cell Signaling and AdhesionJOE RAMOS; Fiscal Year: 2006..Moreover, this work will elucidate the potential role of PEA-15 in the pathogenesis of cancer and diabetes. ..
- Functional Substrates of Long-Term Motor LearningScott Grafton; Fiscal Year: 2006..The experiments demanding extensive practice are particularly relevant for developing rational pathophysiologic models of brain plasticity that are applicable to studies of functional recovery after stroke. [unreadable] [unreadable]..
- Aerobic Exercise, Diet and Cholesterol: A Meta-AnalysisGeorge A Kelley; Fiscal Year: 2010..This is important since one of the major goals of the Department of Health and Human Services is to increase the quality and years of healthy life. ..
- Outcomes of Perinatal StrokeMeredith Golomb; Fiscal Year: 2008..During the last year of the study, she plans to apply for an R01 grant to set up a pilot clinical trial. [unreadable] [unreadable]..
- Inflammatory response to sleep apnea in obese subjectsJULIO ALONSO CHIRINOS MEDINA; Fiscal Year: 2010..We propose that this study design will provide the best way to separate the independent effects of obesity and OSA on cardiovascular risk. ..
- EXERCISE AND BLOOD PRESSURE IN CHILDREN: A META-ANALYSISGeorge Kelley; Fiscal Year: 2001..The investigators state that the results of this project will provide clarification regarding the role of exercise in reducing resting systolic and diastolic blood pressure in children and adolescents. ..
- Regulation of Cell Signaling and AdhesionJOE RAMOS; Fiscal Year: 2007..This will determine if PEA-15 is a suitable target for the development of new cancer therapies and if it can be used as a marker for cancer progression. ..
- Gene-enviornment interactions in facial cleftsKaare Christensen; Fiscal Year: 2006..This study will provide a new level of understanding for a complex birth defect trait. ..
- Repressive Style, suppression and chronic PainJohn Burns; Fiscal Year: 2004..Moreover, findings should provide theoretical principles on which to found new intervention strategies (e.g., "regulating" suppression by engaging in cognitive exercises). ..
- TRAINING IN COGNITIVE AND COMPUTATIONAL NEUROSCIENCEMichael Arbib; Fiscal Year: 2002..The plan for the postdoctoral position focuses on permitting a student trained in psychology or linguistics to gain additional expertise related to cognitive and computational neuroscience. ..
- Motor Unit Activity and Force Steadiness Changes w AgingLisa Griffin; Fiscal Year: 2007..This elucidation of the neuromuscular mechanisms that enable hand steadiness will provide the foundation for the design of advanced rehabilitation systems. ..
- ANGER, SYMPTOM SPECIFIC REACTIVITY AND CHRONIC PAINJohn Burns; Fiscal Year: 2002..Documenting a link between anger and LP reactivity will give empirical justification for targeting problematic anger among CLPB patients, and will provide principles on which to found new intervention strategies. ..