body constitution

Summary

Summary: The physical characteristics of the body, including the mode of performance of functions, the activity of metabolic processes, the manner and degree of reactions to stimuli, and power of resistance to the attack of pathogenic organisms.

Top Publications

  1. ncbi Obesity in children and young people: a crisis in public health
    T Lobstein
    IASO International Obesity TaskForce, 231 North Gower Street, London NW1 2NS, UK
    Obes Rev 5:4-104. 2004
  2. ncbi Differences in body mass index and waist: hip ratios in North Indian rural and urban populations
    K S Reddy
    Department of Cardiology, All India Institute of Medical Sciences, New Delhi
    Obes Rev 3:197-202. 2002
  3. ncbi The development of waist circumference percentiles in British children aged 5.0-16.9 y
    H D McCarthy
    School of Health and Sports Science, The University of North London, London, UK
    Eur J Clin Nutr 55:902-7. 2001
  4. ncbi Comparisons of waist circumferences measured at 4 sites
    Jack Wang
    Body Composition Unit and New York Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York 10025, USA
    Am J Clin Nutr 77:379-84. 2003
  5. ncbi Size control in animal development
    I Conlon
    Developmental Neurobiology Programme, Medical Research Council Laboratory for Molecular Cell Biology, University College London, United Kingdom
    Cell 96:235-44. 1999
  6. ncbi BCQ+: a body constitution questionnaire to assess Yang-Xu. Part II: Evaluation of reliability and validity
    Li Li Chen
    Graduate Institute of Chinese Medical Science, China Medical University, No 91 Hsueh Shih Road, Taichung, Taiwan
    Forsch Komplementmed 16:20-7. 2009
  7. ncbi Predictors of the metabolic syndrome and correlation with computed axial tomography
    Alfonso Soto González
    Department of Endocrinology and Nutrition, Juan Canalejo Hospital, The Coruña, Spain
    Nutrition 23:36-45. 2007
  8. ncbi BCQ+: a body constitution questionnaire to assess Yang-Xu. Part I: establishment of a first final version through a Delphi process
    Yi Chang Su
    Graduate Institute of Chinese Medicine, China Medical University, Taichung, Taiwan
    Forsch Komplementmed 15:327-34. 2008
  9. ncbi Upper abdominal obesity, insulin resistance and breast cancer risk
    B A Stoll
    Oncology Department, St Thomas Hospital, London, UK
    Int J Obes Relat Metab Disord 26:747-53. 2002
  10. ncbi Case-control study of anthropometric measures and breast cancer risk
    Christine M Friedenreich
    Division of Epidemiology, Prevention and Screening, Alberta Cancer Board, Calgary, Canada
    Int J Cancer 99:445-52. 2002

Research Grants

  1. WILD DERIVED MOUSE STOCKS--NEW MODELS FOR AGING RESEARCH
    Richard Miller; Fiscal Year: 2004
  2. Genetics of Longevity and Age-Sensitive Traits in Mice
    Richard Miller; Fiscal Year: 2008
  3. GENETICS OF AGE SENSITIVE TRAITS IN MICE
    Richard Miller; Fiscal Year: 2003
  4. DIET AND PHYSICAL ACTIVITY INTERACTIONS IN OBESITY
    James O Hill; Fiscal Year: 2010
  5. Hemodynamic predictors of brain and cognitive aging
    Naftali Raz; Fiscal Year: 2005
  6. Diet and Exercise: Race, Postmenopause and Metabolism
    ALICE RYAN; Fiscal Year: 2005
  7. THE NIGHT EATING SYNDROME
    Albert Stunkard; Fiscal Year: 2005
  8. MRI Visceral Adipose Tissue Partitioning:Advanced Models
    Steven Heymsfield; Fiscal Year: 2005
  9. Racial Differences--Stress Induced Homeostatic Response
    Gregory Harshfield; Fiscal Year: 2005
  10. RCT of a Novel Oral Contraceptive Initiation Method
    Carolyn Westhoff; Fiscal Year: 2004

Detail Information

Publications226 found, 100 shown here

  1. ncbi Obesity in children and young people: a crisis in public health
    T Lobstein
    IASO International Obesity TaskForce, 231 North Gower Street, London NW1 2NS, UK
    Obes Rev 5:4-104. 2004
  2. ncbi Differences in body mass index and waist: hip ratios in North Indian rural and urban populations
    K S Reddy
    Department of Cardiology, All India Institute of Medical Sciences, New Delhi
    Obes Rev 3:197-202. 2002
    ..This difference in prevalence in the urban population could represent the demographic transition in the Indian population...
  3. ncbi The development of waist circumference percentiles in British children aged 5.0-16.9 y
    H D McCarthy
    School of Health and Sports Science, The University of North London, London, UK
    Eur J Clin Nutr 55:902-7. 2001
    ..To develop waist circumference percentile curves for British children and to compare these curves with those from other countries...
  4. ncbi Comparisons of waist circumferences measured at 4 sites
    Jack Wang
    Body Composition Unit and New York Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York 10025, USA
    Am J Clin Nutr 77:379-84. 2003
    ....
  5. ncbi Size control in animal development
    I Conlon
    Developmental Neurobiology Programme, Medical Research Council Laboratory for Molecular Cell Biology, University College London, United Kingdom
    Cell 96:235-44. 1999
  6. ncbi BCQ+: a body constitution questionnaire to assess Yang-Xu. Part II: Evaluation of reliability and validity
    Li Li Chen
    Graduate Institute of Chinese Medical Science, China Medical University, No 91 Hsueh Shih Road, Taichung, Taiwan
    Forsch Komplementmed 16:20-7. 2009
    ..The objective of the present investigation is to assess the reliability and validity of the BCQ+...
  7. ncbi Predictors of the metabolic syndrome and correlation with computed axial tomography
    Alfonso Soto González
    Department of Endocrinology and Nutrition, Juan Canalejo Hospital, The Coruña, Spain
    Nutrition 23:36-45. 2007
    ..We also evaluated the correlation between anthropometric parameters and DXA and computed axial tomography (CAT) in predicting visceral fat...
  8. ncbi BCQ+: a body constitution questionnaire to assess Yang-Xu. Part I: establishment of a first final version through a Delphi process
    Yi Chang Su
    Graduate Institute of Chinese Medicine, China Medical University, Taichung, Taiwan
    Forsch Komplementmed 15:327-34. 2008
    ..To this end, an objective, reliable and rigorous diagnostic tool is required. This study aimed to develop a first final version of the Yang-Xu Constitution Questionnaire...
  9. ncbi Upper abdominal obesity, insulin resistance and breast cancer risk
    B A Stoll
    Oncology Department, St Thomas Hospital, London, UK
    Int J Obes Relat Metab Disord 26:747-53. 2002
    ..The putative role of aberrant insulin signalling in the promotion of mammary carcinogenesis may help to explain clinical relationships between breast cancer risk and age at menarche, pregnancies and onset of obesity...
  10. ncbi Case-control study of anthropometric measures and breast cancer risk
    Christine M Friedenreich
    Division of Epidemiology, Prevention and Screening, Alberta Cancer Board, Calgary, Canada
    Int J Cancer 99:445-52. 2002
    ..These effects were independent of dietary intake and lifetime total physical activity...
  11. ncbi The incidence and persistence of the NCEP (National Cholesterol Education Program) metabolic syndrome. The French D.E.S.I.R. study
    B Balkau
    INSERM U258, Villejuif, France
    Diabetes Metab 29:526-32. 2003
    ..The frequency of this syndrome at baseline and its incidence and persistence at three years is studied in a French population...
  12. ncbi Central adiposity determines prevalence differences of the metabolic syndrome
    Carlos Lorenzo
    Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78284 7873, USA
    Obes Res 11:1480-7. 2003
    ..To compare the expression of the metabolic syndrome in Spain and San Antonio, TX, two populations with major differences regarding their cardiovascular risk profile...
  13. ncbi BCQ-: A Body Constitution Questionnaire to assess Yin-Xu. Part II: evaluation of reliability and validity
    Jui Shan Lin
    Graduate Institute of Chinese Medicine, China Medical University, Taichung, Taiwan
    Forsch Komplementmed 19:285-92. 2012
    ..to develop an effective and reliable diagnostic tool using self-reported data in order to assess the Yin-Xu body constitution. In this study, we further evaluated a provisional 22-item version of the Yin-Xu Body Constitution ..
  14. ncbi Obesity, body fat distribution and incidence of sick leave in the Belgian workforce: the Belstress study
    M Moreau
    Department of Epidemiology and Health Promotion, School of Public Health, Universite Libre de Bruxelles, Brussels, Belgium
    Int J Obes Relat Metab Disord 28:574-82. 2004
    ....
  15. ncbi Waist circumference for the screening of the metabolic syndrome in children
    L A Moreno
    E U Ciencias de la Salud, Universidad de Zaragoza, Zaragoza, Spain
    Acta Paediatr 91:1307-12. 2002
    ..To identify the best anthropometric predictor of the metabolic syndrome in children...
  16. ncbi BCQ-: a body constitution questionnaire to assess Yin-Xu. Part I: establishment of a provisional version through a Delphi process
    Jun Dai Lin
    Graduate Institute of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan
    Forsch Komplementmed 19:234-41. 2012
    ..Traditional Chinese Medicine (TCM) which prescribes tailored treatment based on each patient's different body constitution may provide new strategy to break the bottleneck of modern medicine (MM)...
  17. ncbi Prevalence of coronary heart disease and risk factors in an urban Indian population: Jaipur Heart Watch-2
    Rajeev Gupta
    Department of Medicine, Monilek Hospital and Research Centre, Jaipur
    Indian Heart J 54:59-66. 2002
    ..A repeat cross-sectional survey was carried out to evaluate the changes in the major coronary risk factors in the urban population of Jaipur previously studied in the early 1990s...
  18. ncbi Correlated evolution of morphology and vocal signal structure in Darwin's finches
    J Podos
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson 85721, USA
    Nature 409:185-8. 2001
    ..These data illustrate how morphological adaptation may drive signal evolution and reproductive isolation, and furthermore identify a possible cause for rapid speciation in Darwin's finches...
  19. ncbi Breast-cancer incidence in relation to height, weight and body-fat distribution in the Dutch "DOM" cohort
    R Kaaks
    Unit of Nutrition and Cancer, International Agency for Research on Cancer, Lyon, France
    Int J Cancer 76:647-51. 1998
    ....
  20. ncbi Harmonization of anthropometric measurements for a multicenter nutrition survey in Spanish adolescents
    Luis A Moreno
    E U Ciencias de la Salud, Departamento de Pediatria, Universidad de Zaragoza, Aveñida Domingo Miral s n, 50009 Zaragoza, Spain
    Nutrition 19:481-6. 2003
    ..We describe the standardization process and reliability of anthropometric measurements carried out in a pilot study...
  21. ncbi Classification of human population based on HLA gene polymorphism and the concept of Prakriti in Ayurveda
    Patwardhan Bhushan
    Interdisciplinary School of Health Sciences, University of Pune, Pune, India
    J Altern Complement Med 11:349-53. 2005
    ..This means that current approaches for identifying phenotypes associated with haplotypes may be inadequate...
  22. ncbi The control of body size in insects
    H F Nijhout
    Department of Biology, Duke University, Durham, NC 27708, USA
    Dev Biol 261:1-9. 2003
    ..The ways in which these higher-level regulatory mechanisms interact with cell- and molecular- level mechanisms are beginning to be elucidated...
  23. pmc Shapely centrefolds? Temporal change in body measures: trend analysis
    Martin Voracek
    Department of Psychoanalysis and Psychotherapy, Statistics and Documentation Branch, University of Vienna Medical School, AKH Währinger Gürtel 18 20, A 1090 Wien, Austria
    BMJ 325:1447-8. 2002
  24. ncbi Human obesity: an evolutionary approach to understanding our bulging waistline
    A Lev-Ran
    Maccabi Health Services, Petah Tikva, Israel
    Diabetes Metab Res Rev 17:347-62. 2001
    ..Since long-term weight loss in adults is rarely achievable, public health measures should be aggressively directed at the prevention of obesity from childhood...
  25. ncbi Reference growth curves for cypriot children 6 to 17 years of age
    S C Savva
    Research and Education Foundation of Child Health, Nicosia, Cyprus, Greece
    Obes Res 9:754-62. 2001
    ....
  26. ncbi Metabolic risks identified by the combination of enlarged waist and elevated triacylglycerol concentration
    Henry S Kahn
    Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341 3717, USA
    Am J Clin Nutr 78:928-34. 2003
    ..Abdominal fat and circulating triacylglycerols increase with age, which indicates lipid overaccumulation. Enlarged waist (EW) with elevated triacylglycerols (ET) could identify adults at metabolic risk...
  27. ncbi Body image perception among men in three countries
    H G Pope
    Biological Psychiatry Laboratory, Harvard Medical School McLean Hospital, Belmont, MA 02478, USA
    Am J Psychiatry 157:1297-301. 2000
    ..The authors tested the hypothesis that men in modern Western societies would desire to have a much leaner and more muscular body than the body they actually had or perceived themselves to have...
  28. ncbi Physiome and Sasang Constitutional Medicine
    Eun Bo Shim
    Department of Mechanical and Biomedical Engineering, Kangwon National University, Hyoja Dong, Chuncheon, Kangwon Do 200 701, Republic of Korea
    J Physiol Sci 58:433-40. 2008
    ..It is emphasized that the integrative and creative combination of SCM and physiome will unlock a new era of holistic medicine...
  29. ncbi Female condition influences preferences for sexual dimorphism in faces of male humans (Homo sapiens)
    I S Penton-Voak
    School of Psychology, University of St Andrews, St Andrews, Fife, Scotland
    J Comp Psychol 117:264-71. 2003
    ....
  30. ncbi Evidence for the incompatibility of age-neutral overweight and age-neutral physical activity standards from runners
    P T Williams
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Am J Clin Nutr 65:1391-6. 1997
    ....
  31. ncbi Male size does not affect mating success (of Anopheles gambiae in São Tomé)
    J D Charlwood
    Centro de Malaria e Outras Doencas Tropicais, Instituto de Higiene e Medicina Tropical, Lisbon, Portugal
    Med Vet Entomol 16:109-11. 2002
    ..Also we showed that larval intraspecific competition is probably insignificant in this population of An. gambiae. Thus, the potential success of transgenic An. gambiae is unlikely to be affected by size selection under field conditions...
  32. ncbi Carotenoid availability does not limit the capability of nestling kestrels (Falco tinnunculus) to cope with oxidative stress
    David Costantini
    Dipartimento di Biologia Animale e dell Uomo, Universita La Sapienza, Viale dell Università 32, 00185 Roma, Italy
    J Exp Biol 210:1238-44. 2007
    ..Our results show that (i) in general, younger nestlings actually have to cope with a high free radical production, and (ii) the ability of wild nestling kestrels to cope with oxidative stress is not affected by carotenoid availability...
  33. ncbi Drosophila S6 kinase: a regulator of cell size
    J Montagne
    Friedrich Miescher Institute, Maulbeerstrasse 66, 4058 Basel, Switzerland
    Science 285:2126-9. 1999
    ..Thus, the dS6K gene product regulates cell size in a cell-autonomous manner without impinging on cell number...
  34. ncbi Waist circumference percentiles for Canadian youth 11-18y of age
    P T Katzmarzyk
    School of Physical and Health Education, Queen s University, Kingston, ON, Canada
    Eur J Clin Nutr 58:1011-5. 2004
    ..To develop age- and sex-specific waist circumference reference data for Canadian youth...
  35. ncbi Evolution. Enhanced: A rodent as big as a buffalo
    R McNeill Alexander
    Department of Pure and Applied Biology, University of Leeds, Leeds LS2 9JT, UK
    Science 301:1678-9. 2003
    ..reveals that the capybara would be dwarfed by Phoberomys, a giant rodent the size of a buffalo that lived during the Miocene Epoch...
  36. ncbi Interleukin-1 beta gene polymorphism and traditional constitution in obese women
    Jeong Hoon Lee
    Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk, Republic of Korea
    Int J Neurosci 118:793-805. 2008
    ..007, OR = 0.152). In overweight women, we found an association between the +3953 C/T polymorphism in the IL-1beta gene and BMI. In addition, we found an association among IL-1beta polymorphism, obesity, and Sasang constitution...
  37. pmc The relationship of anthropometric measures to radiological features of the breast in premenopausal women
    N F Boyd
    Division of Epidemiology and Statistics, Ontario Cancer Institute, Toronto, Canada
    Br J Cancer 78:1233-8. 1998
    ..In addition to per cent density, methods should be examined that combine information from these two tissues...
  38. ncbi Abdominal adiposity and clustering of multiple metabolic syndrome in White, Black and Hispanic americans
    I S Okosun
    Department of Community Medicine, Mercer University School of Medicine, Macon, GA 31207, USA
    Ann Epidemiol 10:263-70. 2000
    ..MMS was defined as the occurrence of two or more of either hypertension, type 2 diabetes mellitus, dyslipidemia, hypertriglyceridemia or hyperinsulinemia...
  39. ncbi Measuring dimensions: the regulation of size and shape
    S J Day
    28 St Oswalds Road, York, YO10 4PF, UK
    Development 127:2977-87. 2000
    ..We discuss a hypothesis that the local steepness of a morphogen gradient is a measure of length in one axis, a measure that is used to determine whether there will be net growth or not...
  40. ncbi Metabolic syndrome in Japanese men and women with special reference to the anthropometric criteria for the assessment of obesity: Proposal to use the waist-to-height ratio
    Shiun Dong Hsieh
    Medical Center of Health Science, Toranomon Hospital, Minato ku, Tokyo, Japan
    Prev Med 42:135-9. 2006
    ..Obesity is one of the criteria for defining metabolic syndrome. However, overt obesity in Asians is relatively low despite high prevalence of metabolic risks...
  41. ncbi Prevalence of obesity and associated risk factors in a Turkish population (trabzon city, Turkey)
    Cihangir Erem
    Department of Internal Medicine, Karadeniz Technical University, Trabzon, Turkey
    Obes Res 12:1117-27. 2004
    ....
  42. ncbi Risk factors for breast cancer at young ages in twins: an international population-based study
    Anthony J Swerdlow
    Section of Epidemiology, Institute of Cancer Research, Sutton, UK
    J Natl Cancer Inst 94:1238-46. 2002
    ..Comparison of risk factor levels between affected probands and unaffected twins in twin pairs can provide a unique method to investigate risk factors that act in early life...
  43. ncbi Overweight and obese anovulatory patients with polycystic ovaries: parallel improvements in anthropometric indices, ovarian physiology and fertility rate induced by diet
    Pier Giorgio Crosignani
    Infertility Unit of the First Department Obstetrics and Gynecology, University of Milan, Via della Commenda 12, 20122 Milan, Italy
    Hum Reprod 18:1928-32. 2003
    ..This prospective study evaluated the effect of weight reduction on anthropometric indices and ovarian morphology in anovulatory overweight patients with polycystic ovary syndrome (PCOS)...
  44. pmc Prevalence of obesity in primary care using different anthropometric measures--results of the German Metabolic and Cardiovascular Risk Project (GEMCAS)
    Hans Hauner
    Else Kröner Fresenius Zentrum für Ernährungsmedizin, Technical University Munich, Klinikum rechts der Isar, Ismaninger Str 22, 81675 Munchen, Germany
    BMC Public Health 8:282. 2008
    ....
  45. ncbi Do measures of body fat distribution provide information on the risk of type 2 diabetes in addition to measures of general obesity? Comparison of anthropometric predictors of type 2 diabetes in Pima Indians
    Marshall K Tulloch-Reid
    Diabetes and Arthritis Epidemiology Section, Phoenix Epidemiology and Clinical Research Branch, NIDDK National Institutes of Health, Phoenix, Arizona, USA
    Diabetes Care 26:2556-61. 2003
    ....
  46. ncbi Decrease in serum adiponectin level due to obesity and visceral fat accumulation in children
    Kohtaro Asayama
    Department of Pediatrics, School of Medicine, University of Occupational and Environmental Health, Iseigaoka, Kitakyushu, Japan
    Obes Res 11:1072-9. 2003
    ..To determine whether serum adiponectin is decreased in obesity and is restored toward normal level after treatment in children...
  47. ncbi Central obesity and breast cancer risk: a systematic review
    M Harvie
    University Departments of Medical Oncology, South Manchester University Hospitals, Manchester, UK
    Obes Rev 4:157-73. 2003
    ..Amongst pre-menopausal women, central (not general) obesity may be specifically associated with an increased risk of breast cancer...
  48. ncbi Anthropometry and body composition in northern Asian Indian patients with type 2 diabetes: receiver operating characteristics (ROC) curve analysis of body mass index with percentage body fat as standard
    N K Vikram
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Diabetes Nutr Metab 16:32-40. 2003
    ..To determine the anthropometric profile and appropriate cut off of body mass index (BMI) to define obesity in Asian Indians with Type 2 diabetes mellitus (T2DM)...
  49. ncbi Effect of two modes of antiandrogen treatment on insulin sensitivity and serum leptin in women with PCOS
    Marcin Krotkiewski
    Department of Rehabilitation Medicine, Sahlgrenska University Hospital, Goteborg, Sweden
    Gynecol Obstet Invest 55:88-95. 2003
    ..Serum leptin correlated only with body weight and body fat. It is concluded that leptin levels do not adequately reflect changes in insulin sensitivity or androgen levels after short-term antiandrogen or antigonadotropin treatment...
  50. ncbi Correlations of C-reactive protein levels with anthropometric profile, percentage of body fat and lipids in healthy adolescents and young adults in urban North India
    Naval K Vikram
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Atherosclerosis 168:305-13. 2003
    ..To investigate the relationships of sub-clinical inflammation and regional and generalized obesity and lipids in adolescent and young adult Asian Indians in north India...
  51. ncbi Eating behaviors and indexes of body composition in men and women from the Québec family study
    Véronique Provencher
    Department of Food Sciences and Nutrition, Laval Hospital Research Center, Laval University, Ste Foy, Quebec, Canada
    Obes Res 11:783-92. 2003
    ....
  52. ncbi Body composition as a risk factor for coronary artery disease in Chinese type 2 diabetic patients in Taiwan
    Chin Hsiao Tseng
    Department of Internal Medicine, National Taiwan University Hospital, Taipei
    Circ J 67:479-84. 2003
    ..BMI and WHR were not associated with CAD in similar analyses. In conclusion, %fat was a better predictor for CAD than BMI and WHR in Chinese type 2 diabetic patients in Taiwan...
  53. ncbi Effect of dietary medium- and long-chain triacylglycerols (MLCT) on accumulation of body fat in healthy humans
    Michio Kasai
    Division of Healthcare Science Research Laboratory, Nisshin Oillio LTD, Yokosuka, Kanagawa, Japan
    Asia Pac J Clin Nutr 12:151-60. 2003
    ..The results suggest that the daily intake of MLCT diet could result in a reduction in body weight and in accumulation of body fat, and, moreover, it could reduce serum total cholesterol...
  54. ncbi Obesity and periodontal disease in young, middle-aged, and older adults
    Mohammad S Al-Zahrani
    Department of Periodontics, School of Dentistry, Case Western Reserve University, Cleveland, OH 44106, USA
    J Periodontol 74:610-5. 2003
    ..The purpose of the present study is to examine the relation between body weight and periodontal disease in a representative United States sample...
  55. ncbi Can anthropometric measurements and diet analysis serve as useful tools to determine risk factors for insulin-resistant diabetes type 2 among white and black Americans?
    H G Allen
    Nutrition Program, North Carolina State University, Raleigh, North Carolina, USA
    Nutrition 19:584-8. 2003
    ..In this study we investigated whether anthropometric measurements differ among diabetics of different races. We also evaluated whether nutrient intake of these individuals was related to anthropometric measurement changes...
  56. ncbi Trends in waist circumferences in young British children: a comparative study
    H D McCarthy
    Institute of Health Research and Policy, London Metropolitan University, London, UK
    Int J Obes (Lond) 29:157-62. 2005
    ..To compare waist circumference (a measure of central fatness) and body mass index (BMI, a measure of general fatness) between a contemporary cohort and similar aged British children measured in 1987...
  57. ncbi Anthropometric measures, body composition, body fat distribution, and knee osteoarthritis in women
    Lauren M Abbate
    Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7280, USA
    Obesity (Silver Spring) 14:1274-81. 2006
    ..Increased BMI is a well-recognized risk factor for radiographic knee osteoarthritis (rKOA); however, the contributions of the components of body composition, body fat distribution, and height to this association are not clear...
  58. ncbi Prevalence of metabolic syndrome among Filipino adults aged 20 years and over
    Celeste C Tanchoco
    Food and Nutrition Research Institute, Department of Science and Technology, Gen Santos Ave, Bicutan, Taguig, Metro Manila, Philippines
    Asia Pac J Clin Nutr 12:271-6. 2003
    ....
  59. ncbi Sexual dimorphism in fat patterning in a sample of 5 to 7-year-old children in Oxford
    J Webster-Gandy
    Research Centre for Health Studies, Buckinghamshire Chilterns University College, Chalfont St Giles HP8 4AD, UK
    Int J Food Sci Nutr 54:467-71. 2003
    ..The significance and importance of hip circumference measurements in predicting health outcome is an area that merits further investigation...
  60. ncbi Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease
    Samuel Klein
    Center for Human Nutrition, Washington University School of Medicine, St Louis 63110, USA
    N Engl J Med 350:2549-57. 2004
    ..We evaluated the effect of large-volume abdominal liposuction on metabolic risk factors for coronary heart disease in women with abdominal obesity...
  61. ncbi Association of visceral adipose tissue with incident myocardial infarction in older men and women: the Health, Aging and Body Composition Study
    Barbara J Nicklas
    Section on Gerontology and Geriatric Medicine, Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Am J Epidemiol 160:741-9. 2004
    ..79, 95% confidence interval: 1.24, 2.58 per standard-deviation increase; p < 0.01). The amount of adipose tissue stored in the intraabdominal cavity is an important, independent risk factor for MI in well-functioning, elderly women...
  62. ncbi Exercise-induced reduction in obesity and insulin resistance in women: a randomized controlled trial
    Robert Ross
    School of Physical and Health Education, Department of Medicine, Division of Endocrinology and Metabolism, Queen s University, Kingston, Ontario, Canada
    Obes Res 12:789-98. 2004
    ..To determine the effects of equivalent diet- or exercise-induced weight loss and exercise without weight loss on subcutaneous fat, visceral fat, and insulin sensitivity in obese women...
  63. ncbi Application of three-dimensional body scanner: observation of prevalence of metabolic syndrome
    J D Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Kweishan, Taoyuan Hsien, Taiwan, ROC
    Clin Nutr 23:1313-23. 2004
    ..This retrospective cross-sectional study correlates blood pressure, blood glucose, lipid and uric acid levels with anthropometric measurements...
  64. ncbi Age-related anthropometric remodelling resulting in increased and redistributed adiposity is associated with increases in the prevalence of cardiovascular risk factors in Chinese subjects
    G Neil Thomas
    Department of Community Medicine, University of Hong Kong, Pokfulam, Hong Kong SAR
    Diabetes Metab Res Rev 22:72-8. 2006
    ..Ageing promotes increases in the prevalence of components of the metabolic syndrome, which obesity often underlies...
  65. ncbi The effects of UCP-1 polymorphisms on obesity phenotypes among Korean female subjects
    Hyoung Doo Shin
    SNP Genetics, Complex B, WooLim Lion s Valley, 371 28, Gasan Dong, Geumcheon gu, Seoul 153 803, Republic of Korea
    Biochem Biophys Res Commun 335:624-30. 2005
    ..01, dominant model). In addition, ht3[GAG] was associated with the accelerated reduction of waist-to-hip ratio and body fat mass by very low calorie diet among subjects who finished one-month-weight control program (P=0.05-0.006)...
  66. ncbi Relationships of insulin sensitivity with fatness and fitness and in older men and women
    Pamela Ouyang
    Division of Cardiology, Johns Hopkins Bayview Medical Center, Baltimore, Maryland 21224, USA
    J Womens Health (Larchmt) 13:177-85. 2004
    ..Men and women differ in obesity, body fat distribution, and fitness levels. This cross-sectional study evaluated sex differences in the relationships of insulin sensitivity with fatness and fitness and obesity...
  67. ncbi Potential problems with school health report cards
    Lee M Scheier
    J Am Diet Assoc 104:525-7. 2004
  68. ncbi Regional body composition changes exhibit opposing effects on coronary heart disease risk factors
    Tomohiro Okura
    Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA
    Arterioscler Thromb Vasc Biol 24:923-9. 2004
    ..We investigated how regional body composition measured by dual-energy X-ray absorptiometry (DXA) is associated with risk factors for coronary heart disease (CHD) during weight reduction in obese women...
  69. ncbi Tanita foot-to-foot bioelectrical impedance analysis system validated in older adults
    Julie D Ritchie
    Department of Nutritional Sciences, The Pennsylvania State University, University Park 16802, USA
    J Am Diet Assoc 105:1617-9. 2005
    ..01). The Tanita BIA system provides a valid measure of percent body fat in older adults, and could be a convenient and practical approach for assessment in public health settings...
  70. ncbi Relationship of C-reactive protein with components of the metabolic syndrome in normal-weight and overweight elderly
    Tiny Hoekstra
    Division of Human Nutrition, Wageningen University, PO Box 8129, 6700 EV Wageningen, The Netherlands
    Nutr Metab Cardiovasc Dis 15:270-8. 2005
    ..We aimed to explore in more detail the relationship between CRP and other components of the metabolic syndrome in a general population of 605 Dutch elderly individuals aged 65-84 years...
  71. ncbi Value of body fat mass vs anthropometric obesity indices in the assessment of metabolic risk factors
    A Bosy-Westphal
    Institut fur Humanernahrung und Lebensmittelkunde, Christian Albrechts Universitat zu Kiel, Kiel, Germany
    Int J Obes (Lond) 30:475-83. 2006
    ....
  72. ncbi The interrelationship between insulin secretion and action in type 2 diabetes mellitus with different degrees of obesity: evidence supporting central obesity
    B Susleyici Duman
    Department of Medical Biology and Genetics, Kadir Has University, School of Medicine, Vefa Bey Sok No 5, 80810 Gayrettepe Istanbul, Turkey
    Diabetes Nutr Metab 16:243-50. 2003
    ....
  73. ncbi In vitro mononuclear cell production of tumour necrosis factor-alpha and weight loss
    Alison M Morris
    Department of Physiology, Adelaide University, Adelaide, SA 5000, Australia
    Diabetes Res Clin Pract 63:179-84. 2004
    ..Elevated tumour necrosis factor-alpha (TNF-alpha) production in adipose tissue has been associated with obesity. We investigated whether mononuclear cell production of TNF-alpha decreased with weight loss in an obese population...
  74. ncbi C-reactive protein, adiposity and cardiovascular risk factors in a Mediterranean population
    P GarcIa-Lorda
    Human Nutrition Unit, Department of Biochemistry and Biotechnology, Faculty of Medicine of Reus, Rovira i Virgili University, 43201 Reus, Spain
    Int J Obes (Lond) 30:468-74. 2006
    ..Understanding the distribution of high-sensitivity C-reactive protein (CRP) and its relations with classic cardiovascular risk factors in specific populations is important for further diagnostic use...
  75. ncbi Upward weight percentile crossing in infancy and early childhood independently predicts fat mass in young adults: the Stockholm Weight Development Study (SWEDES)
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Am J Clin Nutr 83:324-30. 2006
    ..Rapid early postnatal weight gain predicts increased subsequent obesity and related disease risks. However, the exact timing of adverse rapid postnatal weight gain is unclear...
  76. ncbi Effects of an ad libitum, high carbohydrate diet and aerobic exercise training on insulin action and muscle metabolism in older men and women
    Nicholas P Hays
    Department of Geriatrics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    J Gerontol A Biol Sci Med Sci 61:299-304. 2006
    ..We hypothesized that ad libitum consumption of a high-carbohydrate diet would result in weight loss and improved ISGD, and that aerobic exercise training would facilitate greater improvements in ISGD compared with diet alone...
  77. ncbi Body composition in the SOS (Swedish Obese Subjects) reference study
    I Larsson
    Department of Body Composition and Metabolism, Sahlgrenska Academy at Goteborg University, SE 41345 Goteborg, Sweden
    Int J Obes Relat Metab Disord 28:1317-24. 2004
    ..Another objective was to examine if secular changes in adipose tissue distribution occurred during the sampling period, 1994-1999...
  78. ncbi Indices of adipose tissue distribution, apolipoproteins B and AI, lipoprotein (a), and triglyceride concentration in children aged 4-11 years: the Third National Health and Nutrition Examination Survey
    R F Gillum
    Centers for Disease Control and Prevention, National Center for Health Statistics, Hyattsville, MD 20782, USA
    J Clin Epidemiol 54:367-75. 2001
    ..Nor was Lp (a) significantly associated with body fat distribution. Casual serum triglyceride levels were significantly positively associated with WHR independent of age and BMI in non-Hispanic white and Mexican American children...
  79. ncbi Plasma interleukin-8 concentrations are increased in obese subjects and related to fat mass and tumor necrosis factor-alpha system
    Marek Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical Academy, Bialystok 15 276, Poland
    J Clin Endocrinol Metab 87:4602-6. 2002
    ..We conclude that plasma IL-8 levels are increased in obese subjects, and are related to FM and TNF-alpha system. Increase in circulating IL-8 might be one of the factors linking obesity with greater cardiovascular risk...
  80. ncbi Liver-fat accumulation and insulin resistance in obese women with previous gestational diabetes
    Mirja Tiikkainen
    Division of Diabetes, Department of Oncology, University of Helsinki, FIN 00029 HUCH, Helsinki, Finland
    Obes Res 10:859-67. 2002
    ..We determined whether fat accumulation in the liver is associated with features of insulin resistance independent of obesity...
  81. ncbi Which aspects of socioeconomic status are related to obesity among men and women?
    K Ball
    School of Health Sciences, Deakin University, Burwood, Victoria, Australia
    Int J Obes Relat Metab Disord 26:559-65. 2002
    ..This study aimed to investigate the relationships between body weight and fat distribution, and four empirically derived domains of socioeconomic status: employment, housing, migration status and family unit...
  82. ncbi Familial resemblance of 7-year changes in body mass and adiposity
    Melanie S Hunt
    School of Kinesiology and Health Science, York University, Toronto, Ontario, Canada
    Obes Res 10:507-17. 2002
    ..To investigate the familial resemblance of 7-year changes in body mass and adiposity among Canadian families...
  83. ncbi A prospective study of adiposity and all-cause mortality: the Malmö Diet and Cancer Study
    Petra H Lahmann
    Malmo University Hospital, Department of Medicine, Lund University, Sweden
    Obes Res 10:361-9. 2002
    ..This study aims to examine the association between various measures of adiposity and all-cause mortality in Swedish middle-aged and older men and women and, additionally, to describe the influences of age and sex on these associations...
  84. ncbi Racial differences in insulin resistance and mid-thigh fat deposition in postmenopausal women
    Alice S Ryan
    Department of Medicine, Division of Gerontology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Obes Res 10:336-44. 2002
    ..To determine whether racial differences in insulin resistance between African American (AA) and white women exist in postmenopausal women and whether they are related to physical fitness and/or obesity...
  85. ncbi Substituting dietary saturated fat with polyunsaturated fat changes abdominal fat distribution and improves insulin sensitivity
    L K M Summers
    Oxford Lipid Metabolism Group, Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Infirmary, Oxford, UK
    Diabetologia 45:369-77. 2002
    ..In practice, it is difficult for people to make these changes. It may be easier to encourage people to switch from a diet rich in saturated fatty acids to one rich in polyunsaturated fatty acids...
  86. ncbi Association of visceral fat with coronary risk factors in a population-based sample of postmenopausal women
    A Hernandez-Ono
    Unidad de Investigacion en Epidemiologia Clinica, Hospital General del CMN La Raza, Instituto Mexicano del Seguro Social, Mexico City, Mexico
    Int J Obes Relat Metab Disord 26:33-9. 2002
    ..To investigate in a population-based random sample of postmenopausal women the adjusted association of visceral adipose tissue (VAT) with coronary risk factors...
  87. ncbi The effects of changes in body mass and subcutaneous fat on the improvement in metabolic risk factors in obese children after short-term weight loss
    K M Sudi
    Institute for Sport Sciences, Karl-Franzens University, Graz, Austria
    Metabolism 50:1323-9. 2001
    ..The contribution of SAT-pattern to the risk factor profile is an issue that needs further investigation...
  88. ncbi The relation of body fat mass and distribution to markers of chronic inflammation
    A Festa
    Department of Medicine, Division of Clinical Epidemiology, University of Texas Health Science Center at San Antonio, Texas, USA
    Int J Obes Relat Metab Disord 25:1407-15. 2001
    ..These associations were not explained by lower S(I) in obese subjects. Chronic, subclinical inflammation may be one pathophysiological mechanism explaining the increased risk of atherosclerotic disease associated with adiposity...
  89. ncbi Body fat and cardiovascular risk factors in Indian men in three geographical locations
    Himangi Govind Lubree
    Diabetes Unit, King Edward Memorial Hospital Research Centre, Rasta Peth, Pune, India
    Food Nutr Bull 23:146-9. 2002
    ..Our results suggest that urbanization increases the risk of hyperglycemia and hypertension independent of the percentage of body fat or its central distribution...
  90. ncbi The insertion/deletion polymorphism of the ACE gene is related to insulin sensitivity in overweight women
    A S Ryan
    Department of Medicine, Division of Gerontology at the University of Maryland School of Medicine, Baltimore, MD, USA
    Diabetes Care 24:1646-52. 2001
    ..The purpose of this study was to investigate the association of the I/D polymorphism of the ACE gene with insulin sensitivity and CHD risk factors...
  91. ncbi The serum concentration of tumor necrosis factor alpha is not an index of growth-hormone- or obesity-induced insulin resistance
    A I Pincelli
    Chair of Endocrinology, University of Milan, IRCCS Ospedale San Luca, Istituto Auxologico Italiano, Milan, Italy
    Horm Res 55:57-64. 2001
    ..They, however, do not exclude that TNF-alpha may induce insulin resistance at tissue level...
  92. ncbi Larger amounts of visceral adipose tissue in Asian Americans
    Y W Park
    Department of Family Medicine, Sungkyunkwan University School of Medicine, Korea
    Obes Res 9:381-7. 2001
    ..DISCUSSION: These data are the first to demonstrate higher amounts of VAT in healthy Asian Americans, a finding that suggests normative VAT values or standards derived from whites may not be applicable to Asians...
  93. ncbi Body size, composition, and blood pressure of high-altitude Quechua from the Peruvian Central Andes (Huancavelica, 3,680 m)
    S Toselli
    Dipartimento di Biologia Evoluzionistica Sperimentale, , Italy
    Am J Hum Biol 13:539-47. 2001
    ..The presence of low adiposity in the Quechua population could be associated with stresses of the high-altitude environment. Mean values of blood pressure are very low and there is no correlation with age...
  94. ncbi Insulin sensitivity regulates autonomic control of heart rate variation independent of body weight in normal subjects
    R Bergholm
    Division of Diabetes, Department of Medicine, University of Helsinki, Helsinki 00290, Finland
    J Clin Endocrinol Metab 86:1403-9. 2001
    ..These data suggest that sympathetic overactivity is not a consequence of hyperinsulinemia...
  95. ncbi Contribution of weight cycling to serum leptin in human obesity
    Z L Benini
    Clinical Nutrition Laboratory, Istituto Auxologico Italiano, Piancavallo, Verbania, Italy
    Int J Obes Relat Metab Disord 25:721-6. 2001
    ....
  96. ncbi Comparison of three-dimensional anthropometric body surface scanning to waist-hip ratio and body mass index in correlation with metabolic risk factors
    Jen Der Lin
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Kweishan, Taoyuan Hsien, Taiwan, R O C
    J Clin Epidemiol 55:757-66. 2002
    ..Further prospective long-term follow-up study is needed to determine the relationships of 3D body scanning data and HI to blood pressure, blood glucose, lipid, and uric acid levels...
  97. ncbi Prevalence of overweight, general and central obesity in 50- to 64-year-olds involved in the EPIC cohort
    M Haftenberger
    Department of Epidemiology, German Institute of Human Nutrition, Potsdam Rehbrucke, Germany
    IARC Sci Publ 156:249-52. 2002
  98. ncbi Association of neck circumference with insulin resistance-related factors
    M Laakso
    Department of Public Health Science and General Practice, University of Oulu, Oulu, Finland
    Int J Obes Relat Metab Disord 26:873-5. 2002
    ..The aim of the present study was to test the association of neck circumference with abdominal and general obesity as well as with insulin resistance related factors...
  99. ncbi Impact of visceral fat on blood pressure and insulin sensitivity in hypertensive obese women
    Alessandra Nunes Faria
    Department of Endocrinology, University of Sao Paulo, School of Medicine, Hospital do Rim e da Hipertensão, Brazil
    Obes Res 10:1203-6. 2002
    ..The relationship among body fat distribution, blood pressure, serum leptin levels, and insulin resistance was investigated in hypertensive obese women with central distribution of fat...
  100. ncbi Comparison of body composition and periodontal disease using nutritional assessment techniques: Third National Health and Nutrition Examination Survey (NHANES III)
    Nelson Wood
    Department of Periodontics, University of Mississippi School of Dentistry, 2500 North State Street, Jackson, MS 39216 4505, USA
    J Clin Periodontol 30:321-7. 2003
    ....
  101. ncbi Effects of identical weight loss on body composition and features of insulin resistance in obese women with high and low liver fat content
    Mirja Tiikkainen
    Department of Medicine, Division of Diabetes, University of Helsinki, FIN 00029 HUCH, Helsinki, Finland
    Diabetes 52:701-7. 2003
    ..These data suggest that LFAT is regulated by factors other than intra-abdominal and subcutaneous fat. Therefore, LFAT does not appear to simply reflect the size of endogenous fat stores...

Research Grants72

  1. WILD DERIVED MOUSE STOCKS--NEW MODELS FOR AGING RESEARCH
    Richard Miller; Fiscal Year: 2004
    ....
  2. Genetics of Longevity and Age-Sensitive Traits in Mice
    Richard Miller; Fiscal Year: 2008
    ..abstract_text> ..
  3. GENETICS OF AGE SENSITIVE TRAITS IN MICE
    Richard Miller; Fiscal Year: 2003
    ..At best, the program may permit the localization of loci that influence multiple age-sensitive domains and are thus plausible candidates for genes that regulate the rate of aging per se. ..
  4. DIET AND PHYSICAL ACTIVITY INTERACTIONS IN OBESITY
    James O Hill; Fiscal Year: 2010
    ..The results of this project will improve a tool that has already been shown to have great potential for helping reduce the high rates of obesity in children. ..
  5. Hemodynamic predictors of brain and cognitive aging
    Naftali Raz; Fiscal Year: 2005
    ....
  6. Diet and Exercise: Race, Postmenopause and Metabolism
    ALICE RYAN; Fiscal Year: 2005
    ..These findings may provide a rationale for targeting specific populations of women who might improve glucose and fat metabolism more from the addition of exercise to hypocaloric weight loss than weight loss alone. ..
  7. THE NIGHT EATING SYNDROME
    Albert Stunkard; Fiscal Year: 2005
    ..She will develop a manual for the treatment of the NES in consultation with the Beck Institute and will test its efficacy. ..
  8. MRI Visceral Adipose Tissue Partitioning:Advanced Models
    Steven Heymsfield; Fiscal Year: 2005
    ..Our findings could help to set new standards for VAT and adipose tissue subcompartment measurement, lower the cost of MRI body composition studies, and improve study power. ..
  9. Racial Differences--Stress Induced Homeostatic Response
    Gregory Harshfield; Fiscal Year: 2005
    ..abstract_text> ..
  10. RCT of a Novel Oral Contraceptive Initiation Method
    Carolyn Westhoff; Fiscal Year: 2004
    ..We will also assess dual method use for STD prevention in the study to adoption of and adherence to oral contraceptives. We will also assess dual method use for STD prevention in the study population. ..
  11. Linkage Studies of Quantitative Ocular Traits
    Barbara Klein; Fiscal Year: 2006
    ..Subsequent follow-up with fine mapping of areas of interest in the genome is planned. ..
  12. Dose and image quality in adult and pediatric CT
    Walter Huda; Fiscal Year: 2006
    ..Determine the choice of kVp/mAs and PR/mAs that minimize patient doses with no loss of diagnostic performance. 3. Help the Radiology community to balance the confliciting requirements of image quality and patient doses in clinical CT. ..
  13. Exercise training and inflammatory risk factors for disability
    Barbara Nicklas; Fiscal Year: 2009
    ....
  14. Obesity-Related Variables and Motor Vehicle Injury
    Shankuan Zhu; Fiscal Year: 2009
    ....
  15. Obesity, Oral Contraception and Ovarian Suppression
    Carolyn Westhoff; Fiscal Year: 2007
    ..This study will have very good power to detect clinically important differences. Results could directly and immediately affect contraceptive practice. ..
  16. DIET AND PHYSICAL ACTIVITY INTERACTIONS IN OBESITY
    James Hill; Fiscal Year: 2007
    ..The results [unreadable] will help identify the changes required in current dietary and physical [unreadable] activity patterns if we are going to be successful in preventing the [unreadable] development of obesity. [unreadable]..
  17. Gene-Specific Responses to Exercise in Discordant Twins
    Paul Williams; Fiscal Year: 2007
    ..DNA samples will be shared with other institutions to cross-validate gene associations identified from training studies or other designs. ..
  18. Pregnancy and Risk Factors for CVD and Type 2 Diabetes
    Erica Gunderson; Fiscal Year: 2006
    ..The study will also assess whether breastfeeding has beneficial effects on risk factors that may help prevent heart disease and diabetes in women. ..
  19. Impaired Sodium Regulation and BP in Obese Youth
    Gregory Harshfield; Fiscal Year: 2006
    ..Finally, measures of target organ change will include left ventricular mass, diastolic function, and glomerular hyperfiltration as estimated from creatinine clearance. ..
  20. Long-Term Exercise Maintenance via Internet Support
    Paul Williams; Fiscal Year: 2006
    ..We estimate that we will be able to detect differences in exercise cessation rates between the intervention and control group of 0.45% in runners and walkers separately (alpha=0.05, 80% statistical power). ..
  21. THE EPIDEMIOLOGY OF BODY MASS INDEX REBOUND
    Stephen Daniels; Fiscal Year: 2004
    ..They further note that elucidation of the determinants of the timing of BMI rebound could lead to the development of clinical and public health strategies to prevent the development of obesity. ..
  22. Behavioral factors and dietary change in WHTFSMP
    Alok Bhargava; Fiscal Year: 2003
    ..Overall, the results will facilitate the design of policies for improving health of especially minority women in the United States and will be useful for analyses of the Women's Health Initiative data. ..
  23. CLINICAL AND EXPERIMENTAL STUDY OF HUMAN OBESITY
    Albert Stunkard; Fiscal Year: 2002
    ..Our ultimate objective is to identify behaviors that contribute to adiposity and that might be modified in programs of prevention and treatment. ..
  24. PROSPECTIVE STUDY OF HEALTH IN RUNNERS AND WALKERS
    Paul Williams; Fiscal Year: 2002
    ..1%). Additionally, a detectable reduction in breast cancer risk as small as 1.5% per mile run in women is calculated, which is below the 1.7% reduction in risk estimated from other published data. ..
  25. PROGRESSION OF NUCLEAR DENSITY OVER A 10-YEAR INTERVAL
    Barbara Klein; Fiscal Year: 2002
    ....
  26. GENETICS OF BITTER TASTE PERCEPTION IN HUMANS
    DANIELLE REED; Fiscal Year: 2002
    ..In Specific Aim 3, the P.I. will initiate an evaluation of candidate genes located within the region identified, by screening for variabilities associated with PROP-taster status. ..
  27. Family Clustering of Incidence & Progression of Cataract
    Barbara Klein; Fiscal Year: 2003
    ..We currently have no funds to support the proposed analyses. We believe this project offers the possibility of examining important hypotheses in a large group of families in a population-based framework. ..
  28. The Prevalence of two eating disorders
    Albert Stunkard; Fiscal Year: 2003
    ..This information will be gathered upon subjects' entry into the Look AHEAD trial and again at six months and one year into treatment to assess the stability of the diagnosis. ..
  29. BEHAVIORAL STRESS AND SODIUM REGULATION IN YOUTHS
    Gregory Harshfield; Fiscal Year: 2001
    ..It will also define the hemodynamic response pattern associated with these changes. Finally, this study will examine these questions in a younger cohort than has been studied previously, providing new information on this population. ..
  30. RNAi Mediated Gene Disruption in Caenorhabditis Elegans
    Wayne Van Voorhies; Fiscal Year: 2006
    ..Such worms could identify candidate genes affecting processes that act "downstream" from the metabolic rate and provide valuable insights into the causes of aging and mechanisms by which it can be attenuated. ..
  31. NEURAL CORRELATES OF AGE RELATED DIFFERENCES IN MEMORY
    Naftali Raz; Fiscal Year: 2003
    ....
  32. Genetic Predictors of Comorbid Depressive Symptoms + CAD
    Jeanne McCaffery; Fiscal Year: 2005
    ....
  33. GIS and Breast Cancer Screening in Saint Louis
    Mario Schootman; Fiscal Year: 2004
    ..abstract_text> ..
  34. BIRTH WEIGHT EFFECT ON BLOOD PRESSURE IN LATE CHILDHOOD
    Bonita Falkner; Fiscal Year: 2001
    ..Alternatively, if post-natal/childhood parameters are the major determinants of later BP, then efforts should focus on effective preventive strategies in childhood, such as obesity. ..
  35. Effects of aging on sleep architecture
    Naresh Punjabi; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  36. Weight cycling and mortality in women
    Alison Field; Fiscal Year: 2007
    ....
  37. Gene-Environment Interactions in Obesity and Diabetes
    Tracy Nelson; Fiscal Year: 2007
    ..Environment: Dr. Nelson will have an outstanding environment in which to carry out the proposed study, as well as, the necessary resources and support to successfully complete her training. ..
  38. Genetic Environmental Relationship Between Bone Obesity and Leptin in Mice
    James M Cheverud; Fiscal Year: 2010
    ..This project will identify novel genes and physiological pathways affecting osteoporosis and examine how genetic and environmentally-based obesity affects bone mass, morphology and biomechanical function. ..
  39. Mechanisms of Aging in the Long-lived Naked Mole-Rat
    Rochelle Buffenstein; Fiscal Year: 2007
    ..These inter-species contrasts involving seven species with varying longevity will be used to test the ubiquity of proximate theories of aging. ..
  40. GENE INTERACTION FOR BODY WEIGHT COMPONENTS IN MICE
    James Cheverud; Fiscal Year: 2002
    ..In addition to positional cloning of the QTLs, congenic strains will be formed for each QTL and will be tested, along with the LGxSM recombinant inbred strains for a variety of obesity-related traits. ..
  41. Family Cardiac Caregiver Investigation to Evaluate Outcomes (FIT-O)
    Lori J Mosca; Fiscal Year: 2010
    ..Improved adherence to evidence-based preventive therapies could have a substantial public health benefit. ..
  42. Emergence of SIB in Developmentally Delayed Individuals
    CURT ALAN SANDMAN; Fiscal Year: 2010
    ..Findings from this project will contribute to the understanding of the emergence and maintenance of SIB. ..
  43. Obesity in early and middle adulthood and retirement
    June Stevens; Fiscal Year: 2004
    ..support researchers interested in undertaking secondary data analyses of data related to ... behavioral research on aging" and "... determinants of retirement .... " ..
  44. VLDL and LDL Particle Types as CHD Risk Factors
    Frank Sacks; Fiscal Year: 2006
    ..abstract_text> ..
  45. Modulation of AhR-dependent signaling by PPARb/d
    Jeffrey M Peters; Fiscal Year: 2010
    ..abstract_text> ..
  46. The molecular basis of morphological evolution
    David L Stern; Fiscal Year: 2010
    ..This detailed analysis of gene regulation promises to provide new insights into how gene regulation functions and evolves in natural species to cause possibly adaptive changes in morphology. ..
  47. MENTORED STUDY OF RENAL TRANSPLANT ALLOCATION EFFICIENCY
    Mark Schnitzler; Fiscal Year: 2005
    ....
  48. Meningioma: Risk Factors and Quality of Life
    Joellen M Schildkraut; Fiscal Year: 2010
    ..This study represents the first concentrated effort to examine environmental and genetic risk factors for meningioma. ..
  49. Apo A2, C1 and C2 and Diet in human apoB Metabolism
    Frank Sacks; Fiscal Year: 2005
    ..abstract_text> ..
  50. Androgens and Cardiovascular Risk in African Americans
    Bonita Falkner; Fiscal Year: 2005
    ..The results of this project can contribute to the development of prevention and earlier intervention strategies, including more specific therapeutic targets, for this high-risk minority population. ..
  51. INSULIN, IGF-1 & CANCERS OF BREAST, ENDOMETRIUM & OVARY
    Rudolf Kaaks; Fiscal Year: 2001
    ..All studies are based on the same underlying population, obtained by combining three prospective cohort studies that are currently ongoing in New York, Umea (Sweden) and Milan (Italy). ..
  52. Geography of Amputations Among African Americans
    Mario Schootman; Fiscal Year: 2005
    ..abstract_text> ..
  53. REGULATION OF SKELETAL GROWTH IN RENAL FAILURE
    CHERYL SANCHEZ; Fiscal Year: 2003
    ....
  54. Genetics Basis of Dietary Obesity in Mice
    James Cheverud; Fiscal Year: 2009
    ..These studies will increase our knowledge of the important physiological effects of dietary fat, including the genetic variants responsible for individual variations in response to a high fat diet. ..
  55. Identifying Susceptibility Genes for Metabolic Syndrome
    James Pankow; Fiscal Year: 2009
    ..Identification of genes influencing the MS will not only further the understanding of etiologic pathways that explain the clustering of abnormalities, but also may offer novel strategies for screening and prevention. ..
  56. SEX STEROID HORMONES AND RISK OF CHD IN WOMEN
    Kathryn Rexrode; Fiscal Year: 2002
    ..The investigators state that since CHD is the leading cause of death in postmenopausal women, examining the effects of endogenous hormones in postmenopausal women is an important and promising area of inquiry. ..
  57. INFLAMMATORY PRECURSORS OF TYPE 2 DIABETES
    James Pankow; Fiscal Year: 2008
    ..abstract_text> ..
  58. Measure Validation and RCT- Dog Bone Cancer Pain Model
    Dorothy Brown; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  59. Telomere Length as a Marker of Cardiovascular Aging
    Ellen Demerath; Fiscal Year: 2005
    ..Telomeric DNA length may thus be found to be a valuable plasma biomarker for the prediction and monitoring of cardiovascular health and aging. ..
  60. HEALTHY WEIGHT MANAGEMENT FOR BREAST CANCER SURVIVORS
    Cheryl Rock; Fiscal Year: 2003
    ..abstract_text> ..
  61. Hormones During Weight Loss in Breast Cancer Survivors
    Cheryl Rock; Fiscal Year: 2004
    ....
  62. DCIS--MAMMOGRAPHIC FEATURES AND PROGNOSIS
    Laurel Habel; Fiscal Year: 2003
    ..abstract_text> ..
  63. Mammographic Density in a Multi-Ethnic Cohort
    Laurel Habel; Fiscal Year: 2005
    ..abstract_text> ..
  64. CELL-SURFACE PROTEINS IN CAMPYLOBACTER FETUS VIRULENCE
    Martin Blaser; Fiscal Year: 2004
    ..Finally, the data generated can be used to develop a mathematical model of antigenic variation that focuses on the relationship between microbial recombination generating diversity and host selection determining the direction of change. ..
  65. MATERNAL CONTROL FEEDING STYLE--EATING/OBESITY EFFECTS
    Myles Faith; Fiscal Year: 2002
    ..In terms of long-term goals, the candidate will obtain the skills to successfully compete for advanced research programs (e.g., FIRST AWARD, RO-1) concerning environmental influences on child eating behavior and adiposity. ..
  66. Clinical and experimental studies of obesity
    Myles Faith; Fiscal Year: 2008
    ..abstract_text> ..
  67. H PYLORI RECOMBINATION AND GASTRIC COLONIZATION
    Martin Blaser; Fiscal Year: 2001
    ..pylori infections. ..
  68. Development of furanones for treatment of anthrax
    Martin Blaser; Fiscal Year: 2005
    ..In initial studies, spores will be given subcutaneosly. Efficacy parameters will be defined as above. Successful trials can lead to phase I studies in humans, and treatment studies in non-human primates. ..
  69. FOOD SUBSTITUTION FOR CHILD NUTRITION/OBESITY PREVENTION
    Myles Faith; Fiscal Year: 2007
    ..This investigation is designed to provide new insights into environmental manipulations that will induce food substitutions compatible with obesity prevention, while advancing behavioral-economics theory. ..
  70. Apolipoproteins and the complications of Type 1 diabetes
    Timothy Lyons; Fiscal Year: 2005
    ..The study brings together a unique population (DCCT/EDIC) with an important descriptor of lipoproteins never used in Type 1 diabetes, with the goal of preventing and treating complications ..