physiologic nystagmus

Summary

Summary: Involuntary rhythmical movements of the eyes in the normal person. These can be naturally occurring as in end-position (end-point, end-stage, or deviational) nystagmus or induced by the optokinetic drum (NYSTAGMUS, OPTOKINETIC), caloric test, or a rotating chair.

Top Publications

  1. ncbi The critical role of velocity storage in production of motion sickness
    Bernard Cohen
    Department of Neurology, Mount Sinai School of Medicine, New York, New York 10029, USA
    Ann N Y Acad Sci 1004:359-76. 2003
  2. ncbi [Vibration-induced nystagmus: mechanism and clinical interest]
    E Ulmer
    Cabinet ORL Sicot Ulmer 88, Bd Carnot 06400 Cannes
    Ann Otolaryngol Chir Cervicofac 121:95-103. 2004
  3. ncbi Nonlinear nystagmus processing causes torsional VOR nonlinearity
    E Schneider
    Ludwig Maximilians University, Department of Neurology and Center for Sensorimotor Research, Munich, Germany
    Ann N Y Acad Sci 1004:500-5. 2003
  4. ncbi Dissociated eye movements: a clinical study
    Pedro Luiz Mangabeira Albernaz
    Department of Otorhinolaryngology Head and Neck Surgery, Federal University of Sao Paulo, Paulista Medical School, Sao Paulo, Brazil
    Acta Otolaryngol 125:495-8. 2005
  5. ncbi Combined influence of vergence and eye position on three-dimensional vestibulo-ocular reflex in the monkey
    H Misslisch
    Department of Neurology, University of Zurich, 8091 Zurich, Switzerland
    J Neurophysiol 88:2368-76. 2002
  6. ncbi Multiple positional nystagmus suggests multiple canal involvement in benign paroxysmal vertigo
    Jose A Lopez-Escamez
    Otology and Neurotology Group, CTS495, Department of Surgery, Hospital de Poniente de Almeria, El Ejido, Almeria, Spain
    Acta Otolaryngol 125:954-61. 2005
  7. ncbi Triple semicircular canal occlusion in guinea pigs with endolymphatic hydrops
    Shankai Yin
    Department of Otolaryngology, Affiliated Sixth People s Hospital, Shanghai Jiao Tong University, Shanghai, China
    Otol Neurotol 27:78-85. 2006
  8. ncbi The subjective visual vertical in benign paroxysmal positional vertigo. A preliminary study
    F M S Boleas-Aguirre
    Clinica Universitaria de Navarra, Dpto de ORL, Pio XII 36, 31008 Pamplona, Navarra, Spain
    Rev Laryngol Otol Rhinol (Bord) 126:253-5. 2005
  9. ncbi [Benign paroxysmal positional vertigo of the horizontal and superior semicircular canals]
    J P Sauvage
    CHU Dupuytren, Service ORL, 2 rue Martin Luther King, F 87000 Limoges, France
    Rev Laryngol Otol Rhinol (Bord) 126:257-62. 2005
  10. ncbi What is the true incidence of horizontal semicircular canal benign paroxysmal positional vertigo?
    Burak Omur Cakir
    Sisli Etfal Education and Research Hospital, I Department of Otorhinolaryngology Head and Neck Surgery, Kagithane, Istanbul, Turkey
    Otolaryngol Head Neck Surg 134:451-4. 2006

Research Grants

Detail Information

Publications159 found, 100 shown here

  1. ncbi The critical role of velocity storage in production of motion sickness
    Bernard Cohen
    Department of Neurology, Mount Sinai School of Medicine, New York, New York 10029, USA
    Ann N Y Acad Sci 1004:359-76. 2003
    ....
  2. ncbi [Vibration-induced nystagmus: mechanism and clinical interest]
    E Ulmer
    Cabinet ORL Sicot Ulmer 88, Bd Carnot 06400 Cannes
    Ann Otolaryngol Chir Cervicofac 121:95-103. 2004
    ..Since that time, several Authors have applied the vibrator test in normal subjects or patients suffering from various well-characterized conditions...
  3. ncbi Nonlinear nystagmus processing causes torsional VOR nonlinearity
    E Schneider
    Ludwig Maximilians University, Department of Neurology and Center for Sensorimotor Research, Munich, Germany
    Ann N Y Acad Sci 1004:500-5. 2003
    ..This method proved to be suitable for determining whether nonlinear processing of nystagmus frequency is responsible for the TVOR nonlinearity...
  4. ncbi Dissociated eye movements: a clinical study
    Pedro Luiz Mangabeira Albernaz
    Department of Otorhinolaryngology Head and Neck Surgery, Federal University of Sao Paulo, Paulista Medical School, Sao Paulo, Brazil
    Acta Otolaryngol 125:495-8. 2005
    ..Dissociation of eye movements is an important sign of functional or organic lesions of the central vestibular system. Qualitative differences in the movements of each eye appear to be more serious than quantitative differences...
  5. ncbi Combined influence of vergence and eye position on three-dimensional vestibulo-ocular reflex in the monkey
    H Misslisch
    Department of Neurology, University of Zurich, 8091 Zurich, Switzerland
    J Neurophysiol 88:2368-76. 2002
    ....
  6. ncbi Multiple positional nystagmus suggests multiple canal involvement in benign paroxysmal vertigo
    Jose A Lopez-Escamez
    Otology and Neurotology Group, CTS495, Department of Surgery, Hospital de Poniente de Almeria, El Ejido, Almeria, Spain
    Acta Otolaryngol 125:954-61. 2005
    ..This includes anterior and horizontal canal variants and multiple positional nystagmus, suggesting combined lesions affecting several canals...
  7. ncbi Triple semicircular canal occlusion in guinea pigs with endolymphatic hydrops
    Shankai Yin
    Department of Otolaryngology, Affiliated Sixth People s Hospital, Shanghai Jiao Tong University, Shanghai, China
    Otol Neurotol 27:78-85. 2006
    ..This surgery is safe in ears with endolymphatic hydrops...
  8. ncbi The subjective visual vertical in benign paroxysmal positional vertigo. A preliminary study
    F M S Boleas-Aguirre
    Clinica Universitaria de Navarra, Dpto de ORL, Pio XII 36, 31008 Pamplona, Navarra, Spain
    Rev Laryngol Otol Rhinol (Bord) 126:253-5. 2005
    ..This might imply that the limited damage induced by the dislodged otoconia does not disrupt utricular function or that the saccule is the source of the problem...
  9. ncbi [Benign paroxysmal positional vertigo of the horizontal and superior semicircular canals]
    J P Sauvage
    CHU Dupuytren, Service ORL, 2 rue Martin Luther King, F 87000 Limoges, France
    Rev Laryngol Otol Rhinol (Bord) 126:257-62. 2005
    ..The liberatory manoeuvre is a Semont manoeuvre, which is identical to that we would make for a contra-lateral BPPV of the posterior canal...
  10. ncbi What is the true incidence of horizontal semicircular canal benign paroxysmal positional vertigo?
    Burak Omur Cakir
    Sisli Etfal Education and Research Hospital, I Department of Otorhinolaryngology Head and Neck Surgery, Kagithane, Istanbul, Turkey
    Otolaryngol Head Neck Surg 134:451-4. 2006
    ..To assess the correct incidence of horizontal semicircular canal (H-SCC) benign paroxysmal positional vertigo (BPPV)...
  11. pmc Diagnostic and treatment strategy of lateral semicircular canal canalolithiasis
    G Asprella Libonati
    Unit of Audiology Vestibology and Phoniatrics, Department of Otorhinolaryngology and Head Neck Surgery, Madonna delle Grazie Hospital, Matera, Italy
    Acta Otorhinolaryngol Ital 25:277-83. 2005
    ....
  12. ncbi Vestibulo-oculomotor behaviour in rats following a transient unilateral vestibular loss induced by lidocaine
    A K Magnusson
    Department of Biomedicine and Surgery, Faculty of Health Sciences, SE 581 85, Linkoping, Sweden
    Neuroscience 120:1105-14. 2003
    ..By using this method, it is possible to study immediate behavioural consequences and possible neural changes that might outlast the nerve blockade...
  13. ncbi Treatment of anterior benign paroxysmal positional vertigo by canal plugging: a case report
    Krister Brantberg
    Department of Audiology, Karolinska Hospital, Stockholm, Sweden
    Acta Otolaryngol 122:28-30. 2002
    ..The most provoking head movement for the vertigo/nystagmus was Dix-Hallpike's maneuver with the affected ear lowermost...
  14. ncbi Effectiveness of the particle repositioning maneuver in benign paroxysmal positional vertigo with and without additional vestibular pathology
    Lea Pollak
    Department of Neuro otology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, England, UK
    Otol Neurotol 23:79-83. 2002
    ....
  15. pmc Clinical characteristics of benign paroxysmal positional vertigo in Korea: a multicenter study
    So Young Moon
    Department of Neurology, College of Medicine, Seoul National University, Seoul, Korea
    J Korean Med Sci 21:539-43. 2006
    ..9%). The high incidence of HC-BPPV in this study may be explained by relatively shorter time interval between the symptom onset and visit to the Dizziness Clinics in Korea, compared with previous studies in other countries...
  16. ncbi Benign positional nystagmus: a study of its three-dimensional spatio-temporal characteristics
    S T Aw
    Neurology Department, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Sydney, Australia
    Neurology 64:1897-905. 2005
    ..To describe the spatial and temporal characteristics of benign positional nystagmus (BPN) subtypes in benign positional vertigo (BPV) due to vestibular lithiasis affecting one or more semicircular canals (SCCs)...
  17. ncbi Protective effect of edaravone against streptomycin-induced vestibulotoxicity in the guinea pig
    Osamu Horiike
    Department of Otolaryngology, Yamaguchi University School of Medicine, 1 1 1 Minamikogushi, Yamaguchi 755 8505, Ube, Japan
    Eur J Pharmacol 464:75-8. 2003
    ..Animals injected with saline showed statistically smaller gains than those injected with edaravone. These results suggest that edaravone suppresses streptomycin-induced vestibulotoxicity...
  18. ncbi Otolith dysfunction during vertiginous attacks in Ménière's disease
    Ryota Oku
    Department of Otolaryngology, Head and Neck Surgery, University of Nagasaki, Nagasaki, Japan
    Acta Otolaryngol 123:1035-9. 2003
    ..The purpose of this study was to evaluate otolith dysfunction during vertiginous attacks of MD or delayed endolymphatic hydrops...
  19. ncbi Dynamics of the vestibulo-ocular reflex in patients with the horizontal semicircular canal variant of benign paroxysmal positional vertigo
    Kazunori Sekine
    Department of Otolaryngology, University of Tokushima School of Medicine, Tokushima, Japan
    Acta Otolaryngol 124:587-94. 2004
    ..In this study, we assessed the dynamics of the vestibulo-ocular reflex (VOR) of the HSCC in patients with H-BPPV...
  20. ncbi Subclassification of vestibular disorders by means of statistical analysis in caloric labyrinth testing
    Philip Düwel
    Department of Otorhinolaryngology and Plastic Surgery, University of Aachen, Aachen, Germany
    Acta Otolaryngol 124:595-602. 2004
    ..Therefore, the authors present a multivariate analysis of nystagmus findings with the aim of increasing the precision of diagnostic differentiation in cases of vestibular dysfunction...
  21. ncbi Evidence for interacting cortical control of vestibular function and spatial representation in man
    J Ventre-Dominey
    INSERM and CNRS Cognitive Sciences Institute UMR 5015, 67 Bd Pinel, 69500, Bron, France
    Neuropsychologia 41:1884-98. 2003
    ..e. in right cortical lesions with hemi-neglect syndrome. These results demonstrate in man, the existence of a cortical influence on vestibular function related to the mechanisms of spatial representation...
  22. ncbi A new rotational test for vertical semicircular canal function
    Masahiro Morita
    Department of Otolaryngology, Minoo Municipal Hospital, Osaka University Medical School, 5 7 1 Kayano Minoo, Osaka 562 8562, Japan
    Auris Nasus Larynx 30:233-7. 2003
    ..We developed a new rotating chair in order to assess the function of the vertical semicircular canal (VSCC) by analyzing VSCC-induced post-rotatory nystagmus (PRN)...
  23. ncbi The vertical linear vestibulo-ocular reflex in patients with a hyperactive response during horizontal angular acceleration
    Frank Schmäl
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Munster, Munster, Germany
    Acta Otolaryngol 123:606-11. 2003
    ..The aim of this prospective study was to determine whether these patients also show hyperactivity of the linear VOR (LVOR)...
  24. ncbi The relation of motion sickness to the spatial-temporal properties of velocity storage
    Mingjia Dai
    Department of Neurology, Mount Sinai School of Medicine, 1 East 100th Street, Box 1135, New York, NY 10029, USA
    Exp Brain Res 151:173-89. 2003
    ....
  25. ncbi Vertical canal function in normal subjects and patients with benign paroxysmal positional vertigo
    Kazunori Sekine
    Department of Otolaryngology, University of Tokushima School of Medicine, Tokushima, Japan
    Acta Otolaryngol 124:1046-52. 2004
    ..To assess the dynamics of the vertical semicircular canal (VSCC)-ocular reflex in normal subjects and then to compare their gain in VSCC-ocular reflex with that of patients with benign paroxysmal positional vertigo (BPPV)...
  26. ncbi Artificial gravity--head movements during short-radius centrifugation: influence of cognitive effects
    Philippe Meliga
    Man Vehicle Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA
    Acta Astronaut 56:859-66. 2005
    ..No significant difference in habituation was observed between the "fight" and "go" trials...
  27. ncbi Vestibular function at the end of intratympanic gentamicin treatment of patients with Ménière's disease
    Nicolas Perez
    Department of Otolaryngology, University Hospital and Medical School, University of Navarra, Spain
    J Vestib Res 15:49-58. 2005
    ..The changes observed in the VOR correlate well with the results of bedside examination of vestibular function, which in turn reflects the damage induced by intratympanic gentamicin injection...
  28. ncbi Audiovestibular dysfunction in alcohol dependence. Are we worried?
    Roshan K Verma
    Department of Otolaryngology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Am J Otolaryngol 27:225-8. 2006
    ..To study the audiovestibular function in patients of long-term alcohol dependence and compare these changes with social users of alcohol and complete abstainers...
  29. ncbi Persistent geotropic nystagmus--a different kind of cupular pathology and its localizing signs
    Johan Bergenius
    Department of Audiology, Karolinska University Hospital, Stockholm, Sweden
    Acta Otolaryngol 126:698-704. 2006
    ..It is possible to determine the side of the affected cupula by recording the nystagmus pattern in yaw and pitch plane...
  30. ncbi Efficacy of tilt-suppression in postrotatory nystagmus in cats
    Hiroaki Fushiki
    Department of Otolaryngology, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama shi, Toyama 930 0194, Japan
    Brain Res 1108:127-32. 2006
    ....
  31. pmc Three dimensional kinematics of rapid compensatory eye movements in humans with unilateral vestibular deafferentation
    Jun Ru Tian
    Department of Ophthalmology, University of California, Los Angeles, CA 90095 7002, USA
    Exp Brain Res 182:143-55. 2007
    ..ADs have kinematics that neither conform to LL nor match the VOR axis, but appear instead programmed in 3D to correct VOR axis errors...
  32. ncbi Chronic vestibulo-ocular reflexes evoked by a vestibular prosthesis
    Daniel M Merfeld
    Jenks Vestibular Physiology Lab, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    IEEE Trans Biomed Eng 54:1005-15. 2007
    ..This suggests that long-term functional replacement of absent vestibular function is feasible...
  33. ncbi Monocular electronystagmographic analysis of caloric nystagmus
    Sachiko Aoki
    Department of Otolaryngology, Tokyo Women s Medical University, Medical Center East, Tokyo, Japan
    Int Tinnitus J 13:51-5. 2007
    ..The activities of postrotatory nystagmus were almost equal in both eyes in 50 patients. We concluded that the inhibitory effect of cold caloric stimulation is probably transmitted more intensively to the eye on the irrigated side...
  34. ncbi Monitoring of caloric response and outcome in patients with benign paroxysmal positional vertigo
    Maria I Molina
    Otology and Neurotology Group CTS495, Department of Surgery, Hospital de Poniente de Almeria, El Ejido, Almeria, Spain
    Otol Neurotol 28:798-800. 2007
    ..To analyze the time course of caloric response in patients with Benign Paroxysmal Positional Vertigo (BPPV)...
  35. ncbi Changes in slow phase eye velocity and time constant of positional nystagmus at transform from cupulolithiasis to canalolithiasis
    Takao Imai
    Department of Otolaryngology, Osaka University Medical School, Osaka, Japan
    Acta Otolaryngol 128:22-8. 2008
    ..The present findings suggested that in both patients, at the period of an increase of SPEV of the positional nystagmus with the shortening of its TC, cupulolithiasis transformed into canalolithiasis...
  36. ncbi Dynamics of canal response to head-shaking test in benign paroxysmal positional vertigo
    Jose A Lopez-Escamez
    Otology and Neurotology Group, Department of Surgery, Hospital de Poniente, El Ejido, Almeria, Spain
    Acta Otolaryngol 127:1246-54. 2007
    ..We suggest that vestibular lithiasis has a limited contribution to the mechanism that generates HSN...
  37. pmc Alexander's law in patients with acute vestibular tone asymmetry--evidence for multiple horizontal neural integrators
    S Hegemann
    Department of Otorhinolaryngology, Head and Neck Surgery, Zurich University Hospital, Frauenklinikstr 24, CH 8091, Zurich, Switzerland
    J Assoc Res Otolaryngol 8:551-61. 2007
    ..We conclude that the theory of a simple leak of a single horizontal neural integrator is not sufficient to explain all aspects of AL...
  38. ncbi Vertical component of the caloric response, including a caloric second phase provoked by positional change: a preliminary report
    Sachiko Aoki
    Department of Otolaryngology, Tokyo Women s Medical University, Medical Center East, Tokyo, Japan
    Int Tinnitus J 13:150-1. 2007
    ..We suspected that the vertical component of the caloric first phase was mainly due to the inhibition of the anterior semicircular canal...
  39. ncbi Influence of caloric and rotation testing upon blood pressure and pulse rate
    M E Norre
    Department of Otoneurology and Equilibriometry, University Hospitals, University of Leuven, Belgium
    Acta Otorhinolaryngol Belg 42:571-9. 1988
    ..There is some correlation between both manifestations, but also some independency in occurrence...
  40. ncbi Evaluation of balance function in peripheral vestibular disorders
    M E Norre
    Dpt Otoneurology and Equilibriometry, University of Leuven, Belgium
    Acta Otorhinolaryngol Belg 43:453-65. 1989
    ..g. Ménière's disease, etc), but it is of primary importance in the determination of a logical and adequate treatment and so for rehabilitation treatment. Some important items are reviewed...
  41. ncbi Vertigo in children
    Katarzyna Pawlak-Osińska
    Collegium Medicum of Nicolaus Copernicus University, Bydgoszcz, Poland
    Int Tinnitus J 12:185-9. 2006
    ..We discussed the probable reasons for vertigo, among which psychogenic origin, side effect of medications, hormonal disturbances, spondylosis, and diet errors had to be taken into consideration...
  42. ncbi Shifts in listing's plane produced by vertical axis rotation: sustained ocular torsion due to semicircular canal stimulation
    Benjamin T Crane
    Department of Surgery, Division of Otolaryngology, University of California, Los Angeles, California 90095 7002, USA
    Invest Ophthalmol Vis Sci 48:2076-83. 2007
    ..The present study was conducted to determine whether whole-body yaw alters the position and orientation of LP...
  43. ncbi Is posttraumatic benign paroxysmal positional vertigo different from the idiopathic form?
    Carlos R Gordon
    Department of Neurology, Meir General Hospital, Kfar Saba 44281, Israel
    Arch Neurol 61:1590-3. 2004
    ..Although head trauma is considered a common cause of benign paroxysmal positional vertigo (BPPV), clinical presentation and outcome of traumatic BPPV (t-BPPV) have not been systematically evaluated...
  44. ncbi [Benign paroxysmal positional vertigo of the horizontal semicircular canal]
    E Domenech Campos
    Servicio de Otorrinolaringologia, Hospital Arnau de Vilanova, Valencia
    Acta Otorrinolaringol Esp 57:446-9. 2006
    ..An oculographic study of features in the positional response was carried out. Electrooculograpy (EOG) allows an exhaustive study of positional nystagmus...
  45. ncbi Motion processing asymmetries and stereopsis in infants
    John Wattam-Bell
    Visual Development Unit, Department of Psychology, University College London, London WCIE 6BT, UK
    Vision Res 43:1961-8. 2003
    ..It is possible that they reflect asymmetrical directional responses in extrastriate visual cortex (e.g. area V5/MT)...
  46. ncbi Streptomycin action to the mammalian inner ear vestibular organs: comparison between pigmented guinea pigs and rats
    Graciela Meza
    Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F, Mexico
    Comp Biochem Physiol C Toxicol Pharmacol 146:203-6. 2007
    ..We hypothesize differential drug metabolism and distribution and conclude that results in laboratory animals may not always be applicable in the human situation...
  47. ncbi Otolith effect on torsional quick phases of vestibular nystagmus in humans
    A A Kori
    Neurology Department, Zurich University Hospital, Zurich, Switzerland
    Ann N Y Acad Sci 956:572-3. 2002
  48. ncbi Nystagmus using video-oculography in psychiatric patients
    Kensuke Kiyomizu
    Department of Otorhinolaryngology, University of Miyazaki, Japan
    Eur Arch Otorhinolaryngol 266:1167-74. 2009
    ..These results indicate that nystagmus may also be a very important clinical finding not only in patients with neurological and neuro-otological diseases, but also in patients with psychiatric diseases...
  49. ncbi A new clinical classification for Usher's syndrome based on a new subtype of Usher's syndrome type I
    C R Otterstedde
    Department of Otolaryngology-Head and Neck Surgery, University of Heidelberg, Germany
    Laryngoscope 111:84-6. 2001
    ..Therefore we describe a new subtype of Usher's syndrome type I and suggest a modified clinical classification for Usher's syndrome...
  50. ncbi Different forms of dizziness occurring after cochlear implant
    T Kubo
    Department of Otolaryngology, Osaka University Graduate School of Medicine, Suita City, Japan
    Eur Arch Otorhinolaryngol 258:9-12. 2001
    ..These findings suggest that inner ear lesions due to cochlear implant surgery develop gradually. Similarities in clinical features between delayed-V and Ménière's disease indicate the presence of labyrinthine hydrops...
  51. ncbi Dizziness, migrainous vertigo and psychiatric disorders
    R Teggi
    Department of ENT, San Raffaele Hospital, Vita Salute University, Milan, Italy
    J Laryngol Otol 124:285-90. 2010
    ..This study sought to establish the prevalence of vestibular disorders, migraine and definite migrainous vertigo in patients with psychiatric disorders who were referred for treatment of dizziness, without a lifetime history of vertigo...
  52. ncbi Recovery of vestibulogastrointestinal symptoms during vestibular compensation after unilateral labyrinthectomy in rats
    Jae Hee Lee
    Department of Physiology, Wonkwang University School of Medicine, Vestibulocochlear Research Center and Brain Research Institute at Wonkwang University, Iksan, Korea
    Otol Neurotol 31:241-9. 2010
    ..Thus, the temporal changes and the role of the cerebellum in the recovery of vestibulogastrointestinal symptoms after unilateral labyrinthectomy (UL) were investigated in this study...
  53. ncbi Heart rate and blood pressure effects during caloric vestibular testing
    Anand V Kasbekar
    Department of Otolaryngology, Cambridge University Hospitals NHS Foundation Trust, UK
    J Laryngol Otol 124:616-22. 2010
    ..To determine whether the caloric vestibular test causes significant changes in heart rate and mean arterial blood pressure...
  54. ncbi Dynamic pitch rotation affects eye torsion
    Shirley G Diamond
    Department of Psychology, University of California at Santa Barbara, Santa Barbara, California 93106, USA
    Acta Otolaryngol 126:248-53. 2006
    ..Opposite responses may be the result of individual variation in anatomical or physiological vector orientations of hair cells in the anterior or posterior utricle or in the saccule...
  55. ncbi Clinical significance of positionally induced downbeat nystagmus
    R John Leigh
    Ann Neurol 53:688. 2003
  56. ncbi The effects of intense click sounds on velocity storage in optokinetic after-nystagmus
    O Sasaki
    Department of Otolaryngology, Shinshu University School of Medicine, Matsumoto, Japan
    Eur Arch Otorhinolaryngol 257:490-2. 2000
    ..There was no effect on OKAN with unilateral stimulation but binaural stimulation suppressed it. These results suggest that a velocity storage integrator is influenced by intense clicks via the otolithic area...
  57. ncbi Eye velocity asymmetry, ocular orientation, and convergence induced by angular rotation in the rabbit
    Jun Maruta
    Department of Neurology, Mount Sinai School of Medicine, New York, NY, USA
    Vision Res 46:961-9. 2006
    ..Thus, mechanisms in the rabbit increase compensatory eye velocity in the eye that leads into the direction of rotation and enhance binocular vision...
  58. ncbi Oculomotor plasticity: are mechanisms of adaptation for reactive and voluntary saccades separate?
    Nadia Alahyane
    INSERM, U864, Espace et Action, 16 Avenue Lepine, Bron, F 69500, France
    Brain Res 1135:107-21. 2007
    ..Based on these findings, it is proposed that adaptations of RS and SVS may involve a neural network including both a common site and two separate sites specifically recruited for each saccade type...
  59. ncbi Diazepam tolerance effects on vestibular function testing, part II: vestibulo-ocular reflex parameters during rotational testing
    Patricia A Blau
    Dept of Otorhinolaryngology, University of Texas Southwestern Medical Center at Dallas, TX 75390 8876, USA
    Ann Otol Rhinol Laryngol 114:722-9. 2005
    ..It has been shown that repeated dosing with DZ leads to accumulation and tolerance in outcome measures that assess memory, sedation, and psychomotor tasks...
  60. ncbi Assessing vestibular function: which tests, when?
    M Fetter
    Department of Neurology, Eberhard Karl University, Tubingen, Germany
    J Neurol 247:335-42. 2000
    ....
  61. ncbi Plastic changes underlying vestibular compensation in the guinea-pig persist in isolated, in vitro whole brain preparations
    N Vibert
    Laboratoire de Neurobiologie des Reseaux Sensorimoteurs, CNRS ESA 7060, Paris, France
    Neuroscience 93:413-32. 1999
    ..This last modification may support a functional substitution of the deficient, vestibular-related synergies involved in gaze and posture stabilization by neck-related reflexes...
  62. ncbi Multivariate vestibular testing: laterality of unilateral Ménière's disease
    P S Dimitri
    Harvard University-Massachusetts Institute of Technology Division of Health Sciences and Technology, Boston, MA, USA
    J Vestib Res 11:405-12. 2001
    ..In the absence of spontaneous or positional nystagmus, asymmetry measurements significantly enhanced right/left discrimination. Directional preponderance was insignificant in determining the side of lesion...
  63. ncbi Effectiveness of particle repositioning maneuvers in the treatment of benign paroxysmal positional vertigo: a systematic review
    Janet Odry Helminski
    Department of Physical Therapy, Midwestern University, 555 31st St, Downers Grove, IL 60515, USA
    Phys Ther 90:663-78. 2010
    ..Benign paroxysmal positional vertigo (BPPV) is the most common cause of vertigo...
  64. ncbi Chiropractic management of a patient with benign paroxysmal positional vertigo: a case report
    Anette R Nørregaard
    Clinical Locomotion Science, Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
    J Manipulative Physiol Ther 32:387-90. 2009
    ....
  65. ncbi Effect of angular acceleration on the localization performance of a remembered target
    Frank Schmäl
    Department of Otorhinolaryngology, University Hospital Munster, Germany
    J Vestib Res 15:81-92. 2005
    ....
  66. ncbi Approach to bilateral benign paroxysmal positioning vertigo
    Lea Pollak
    Department of Neurology, Assaf Harofeh Medical Center, Zerifin, Israel
    Am J Otolaryngol 27:91-5. 2006
    ..Inappropriate head positioning during testing in unilateral BPPV causes the otolith debris in the uppermost ear to move toward the cupula, resulting in an inhibitory nystagmus and mimicking bBPPV...
  67. pmc Motion sickness induced by off-vertical axis rotation (OVAR)
    Mingjia Dai
    Department of Neurology, Mount Sinai School of Medicine, 1 East 100th Street, Box 1135, New York, NY, 10029, USA
    Exp Brain Res 204:207-22. 2010
    ..These results suggest that the sensory-motor conflict that produces motion sickness involves coding of the spatial vertical by the otolith organs and body tilt receptors and processing of eye velocity through velocity storage...
  68. ncbi Dissociated hysteresis of static ocular counterroll in humans
    A Palla
    Department of Neurology, Zurich University Hospital, Zurich, Switzerland
    J Neurophysiol 95:2222-32. 2006
    ..We hypothesize that ocular torsional hysteresis is introduced at the level of the otolith pathways because the direction-dependent torsional position lag of the eyes is related to the head roll position and not the eye position...
  69. ncbi 3D eye movement analysis during sinusoidal off vertical axis rotation in human subjects
    Y Koizumi
    Department of Otolaryngology, Nippon Medical School, Tokyo, Japan
    Acta Otolaryngol 123:121-8. 2003
    ..In order to investigate these characteristics, we performed a 3D analysis of eye movements induced by human sinusoidal s-OVAR, and compared the result with that of eye movements induced by constant c-OVAR...
  70. ncbi Positional vertigo and macroscopic downbeat positioning nystagmus in spinocerebellar ataxia type 6 (SCA6)
    Ichiro Yabe
    Department of Neurology, Hokkaido University Graduate School of Medicine, N15 W7, Kita ku, Sapporo 060 8638, Japan
    J Neurol 250:440-3. 2003
    ..Our findings indicated that DPN is a distinct part of the clinical presentation of SCA6, showing that vestibular cerebellum is more affected in SCA6 than other types of degenerative ataxia...
  71. ncbi Short-latency eye movements evoked by near-threshold galvanic vestibular stimulation
    Alexandra Séverac Cauquil
    Centre de Recherche Cerveau and CognitionUMR 5549 CNRS Université Paul Sabatier, Toulouse, France
    Exp Brain Res 148:414-8. 2003
    ..The overall pattern of eye movement suggests that semicircular canal afferents contribute to these low-intensity GVS responses...
  72. ncbi Three-dimensional analysis of pressure nystagmus in labyrinthine fistulae
    T Yagi
    Department of Otolaryngology, Nippon Medical School, Tokyo, Japan
    Acta Otolaryngol 119:150-3. 1999
    ..On the other hand, pressure nystagmus in cases with fistulae of both the lateral and anterior canals were not aligned with the anatomical axes of the combination of both canals...
  73. ncbi The influence of gravitoinertial force level on oculomotor and perceptual responses to sudden stop stimulation
    P DiZio
    Ashton Graybiel Spatial Orientation Laboratory, Brandeis University, Waltham, Massachusetts 02254
    Aviat Space Environ Med 58:A224-30. 1987
    ..Attenuation of the vestibular response to rotary acceleration in free-fall causes sensory-motor mismatches during natural head movements in orbital flight that may be important factors in the evocation of space motion sickness...
  74. ncbi 3D analysis of human locomotion before and after caloric stimulation
    T Kubo
    Department of Otolaryngology, Osaka University Medical School, Japan
    Acta Otolaryngol 117:143-8. 1997
    ..The importance of the hip joint for locomotion (hip strategy) was confirmed from the present data...
  75. ncbi Pathomechanism of mammalian downbeat nystagmus due to cerebellar lesion: a simple hypothesis
    A Böhmer
    Department of Otorhinolaryngology, University Hospital, Zurich, Switzerland
    Neurosci Lett 250:127-30. 1998
    ..This peripheral vestibular bias is centrally cancelled by floccular and parafloccular inhibitory pathways which are related to the smooth pursuit system, but becomes disinhibited in the presence of posterior cerebellar lesions...
  76. ncbi Differing effects on the inner ear of three gentamicin compounds: GM-C1, -C2 and -C1a
    Masamichi Kobayashi
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Acta Otolaryngol 123:916-22. 2003
    ..In this study we investigated differences in cochleo- and vestibulotoxicity between the three compounds..
  77. ncbi Some effects of sleep loss on vestibular responses
    W E Collins
    Human Resources Research Branch, FAA Civil Aeromedical Institute, Oklahoma City, Oklahoma 73125
    Aviat Space Environ Med 59:523-9. 1988
    ..d-Amphetamine had no consistent effect on responses of control subjects, but significantly increased nystagmus and elevated (but not significantly) measures of turning experiences for the sleep deprived...
  78. ncbi Experimental endolymphatic hydrops: are cochlear and vestibular symptoms caused by increased endolymphatic pressure?
    A Böhmer
    ENT Department, University Hospital, Zurich, Switzerland
    Ann Otol Rhinol Laryngol 99:470-6. 1990
    ..Endolympathic-perilymphatic pressure gradients may contribute to auditory threshold increase in endolymphatic hydrops, but are not its only cause...
  79. ncbi Posterior semicircular canal type benign paroxysmal positioning vertigo with ageotropic paroxysmal positioning nystagmus
    A Rapoport
    Department of Neurology, Wolfson Medical Center, Holon, Israel
    Audiol Neurootol 6:50-3. 2001
    ..Two patients had changing patterns of paroxysmal positioning nystagmus...
  80. ncbi The effect of hyperventilation on downbeat nystagmus in cerebellar disorders
    M F Walker
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Neurology 53:1576-9. 1999
    ..In four of eight patients, hyperventilation produced an increase in the slow-phase velocity of downbeat nystagmus. We speculate that this effect may be mediated through metabolic effects on cerebellar calcium channels...
  81. ncbi Novel subtype of idiopathic bilateral vestibulopathy: bilateral absence of vestibular evoked myogenic potentials in the presence of normal caloric responses
    Chisato Fujimoto
    Department of Otolaryngology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
    J Neurol 256:1488-92. 2009
    ....
  82. ncbi Potential role of anti-GAD antibodies in abnormal eye movements
    Caroline Tilikete
    Neuro Ophthalmology Unit, Hopital Neurologique, Hospices Civils de Lyon, 59 Bd Pinel, 69 677 Bron Cedex, France
    Ann N Y Acad Sci 1039:446-54. 2005
    ..The potential role of antiGAD-Ab and the resultant GABAergic neurotransmission deficit in oculomotor manifestations is discussed...
  83. pmc Short latency disconjugate vestibulo-ocular responses to transient stimuli in the audio frequency range
    P Jombik
    Department of Neurology, Laboratory of Clinical Neurophysiology, Zvolen Hospital, Slovak Republic
    J Neurol Neurosurg Psychiatry 76:1398-402. 2005
    ..To determine whether unilateral activation of the vestibular labyrinth by brief air conducted tones can elicit disconjugate reflex eye movements in healthy subjects...
  84. pmc Biomechanics of horizontal canal benign paroxysmal positional vertigo
    Suhrud M Rajguru
    Department of Bioengineering, University of Utah, Salt Lake City, UT 84112, USA
    J Vestib Res 15:203-14. 2005
    ..The model was further applied to assess the efficacy of a 360 degrees -rotation CRP for the treatment of canalithiasis HC-BPPV...
  85. ncbi Sensation and action during active and passive movement
    M Takahashi
    Department of Otolaryngology, Yamaguchi University School of Medicine, Ube, Japan
    Acta Otolaryngol 119:121-5. 1999
    ..It seems likely that sensation and action, whether they are skilled or ataxic, are controlled by the perception of an outer world which is integrated from visual and vestibular inputs and functions as a vector in the head...
  86. ncbi A maximum motion technique for assessment of color vision defects
    C A Collin
    Psychology Department, McGill University, Montreal, Canada
    Percept Psychophys 60:1337-43. 1998
    ....
  87. ncbi Three-dimensional analysis of post-caloric nystagmus caused by postural change
    Y H Young
    Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan
    Acta Otolaryngol Suppl 545:69-72. 2001
    ..Thus using 3D VNG coupled with postural change during caloric testing, the horizontal or vertical components of PCN can be successfully provoked...
  88. ncbi Differential diagnosis of true and pseudo-bilateral benign positional nystagmus
    Takao Imai
    Department of Otolaryngology, Osaka University Graduate School of Medicine, Osaka, Japan
    Acta Otolaryngol 128:151-8. 2008
    ..Since canalolithiasis in the uppermost PSCC may be transient cupulolithiasis, evoking positional nystagmus with long TC, the diagnosis of the latter patients should be pseudo-bilateral P-BPPN...
  89. pmc Absence of nystagmus during REM sleep in patients with vestibular neuritis
    I Eisensehr
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany
    J Neurol Neurosurg Psychiatry 71:386-9. 2001
    ..The eye movement pattern in REM was the same for patients and controls. In conclusion, peripheral vestibular imbalance producing nystagmus in vestibular neuritis in the awake state is not active at the brain stem level during REM sleep...
  90. ncbi Direction-fixed fluctuating positional nystagmus in a dizzy patient who had a drop attack
    Kenneth H Brookler
    Neurotologic Associates, P C, New York City, USA
    Ear Nose Throat J 83:221-2. 2004
  91. ncbi [Inhibitory effect of yunfujing on vestibular stimulative response in rats and volunteers]
    X Deng
    86th Hospital of PLA
    Zhongguo Zhong Yao Za Zhi 15:240-1, 256. 1990
    ..34 to 759.63 s. In the mean time, no changes of blood pressure and pulse were observed in the treated group...
  92. ncbi Inner ear changes with intracochlear gentamicin administration in Guinea pigs
    Takeshi Okuda
    Department of Otolaryngology, Yamaguchi University School of Medicine, Yamaguchi, Japan
    Laryngoscope 114:694-7. 2004
    ..The authors examined the relation between gentamicin dosages and inner ear function in guinea pigs...
  93. ncbi Orienting eye movements and nystagmus produced by translation while rotating (TWR)
    Jun Maruta
    Department of Neurology and Physiology and Biophysics, Mount Sinai School of Medicine, 1 Gustave L Levy Place, New York, NY 10029, USA
    Exp Brain Res 163:273-83. 2005
    ..We speculate that the brain may use these low amplitude rotating linear accelerations to generate eye velocities that help to orient gaze when making turns during normal locomotion...
  94. ncbi Characteristics of 629 vestibular schwannomas according to preoperative caloric responses
    Stephane Tringali
    Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Département d Otologie et d Oto neurochirurgie, Pierre Benite, France
    Otol Neurotol 31:467-72. 2010
    ..To assess the contribution of preoperative caloric responses in patients with vestibular schwannoma on the following: preoperative parameters and postoperative results (facial function and hearing preservation)...
  95. ncbi Nystagmus measured with video-oculography: methodological aspects and normative data
    Hilla Levo
    Department of Otolaryngology and Head and Neck Surgery, Helsinki University Central Hospital, Helsinki, Finland
    ORL J Otorhinolaryngol Relat Spec 66:101-4. 2004
    ..7 degrees /s). The VOG is a modern and sensitive method to record eye movements, but visual inspection of the videotape may be needed in selected cases to confirm occurrence of nystagmus...
  96. ncbi Visual-vestibular interactions during vestibular compensation: role of the pretectal not in horizontal VOR recovery after hemilabyrinthectomy in rhesus monkey
    C Matthew Stewart
    Department of Otolaryngology, University of Texas Medical Branch, Galveston, 77555 0130, USA
    J Neurophysiol 94:2653-66. 2005
    ..Therefore our studies demonstrate that the NOT is an essential source of visual signals for the process of vestibular compensation after HL...
  97. ncbi [Flow kinetics of endolymph in rotational stimulation]
    H W Pau
    HNO Klinik des Universitäts Krankenhauses Hamburg Eppendorf
    Laryngorhinootologie 68:622-5. 1989
    ..Our results suggest that endolymph flows, evoked either by calorisation or rotation, represent adequate stimuli for vestibular excitability...
  98. ncbi Postural reactions induced by vertical motion of visual scenes and the effects of weightlessness
    G Clement
    Laboratoire de Physiologie de la Perception et de l Action, CNRS College de France, Paris
    Acta Otolaryngol 118:466-73. 1998
    ..This ineffectiveness might reflect a confusion between body tilt and translation as the result of adaptation to weightlessness...
  99. ncbi Time course of vestibular function changes of experimental endolymphatic hydrops in guinea pigs
    Akinobu Kakigi
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Bunkyo ku, Tokyo, Japan
    ORL J Otorhinolaryngol Relat Spec 71:19-25. 2010
    ..To investigate the relationship between endolymphatic hydrops and vestibular dysfunction...
  100. ncbi Eye movements in response to electric stimulation of the human posterior ampullary nerve
    Conrad Wall
    Department of Otology and Laryngology, Harvard Medical School, Boston, MA, USA
    Ann Otol Rhinol Laryngol 116:369-74. 2007
    ..It remains to be shown, however, that electric stimulation of the human end organ or its vestibular nerve branches is capable of eliciting a nystagmic eye movement response...
  101. ncbi Benign paroxysmal positional vertigo. State of the art
    R Boniver
    Acta Otorhinolaryngol Belg 52:281-9. 1998
    ..It recalls the ethiopathogeny of the syndrome and describes the different types of BPV and their treatment by "liberatory maneuvers". The paper also discusses the need for an otoneurological examination to achieve an exact diagnosis...

Research Grants14

  1. DIZZINESS IN OLDER PEOPLE
    Robert Baloh; Fiscal Year: 2006
    ..By continuing this longitudinal study of carefully studied older patients and controls, our multidisciplinary research team is in a good position to achieve our goals. ..
  2. Diseases of the Vestibular System
    Robert Baloh; Fiscal Year: 2006
    ..abstract_text> ..
  3. Development of semicircular canal prostheses for studies of vestibular plasticity
    DANIEL MERFELD; Fiscal Year: 2009
    ..abstract_text> ..
  4. Adaptation to controlled vestibular stimulation
    DANIEL MERFELD; Fiscal Year: 2005
    ..All of these proposed specific aims will be investigated by measuring changes in the vestibulo-ocular responses induced by changes in chronic, patterned, electrical stimulation of the peripheral vestibular system. ..
  5. OCULOMOTOR SYSTEM AND BODY POSTURAL MECHANISMS
    Bernard Cohen; Fiscal Year: 2009
    ..abstract_text> ..
  6. Vestibulocerebellar function in channelopathy mutants
    John Stahl; Fiscal Year: 2004
    ..Thus, the insights into normal cerebellar function generated by this study should also advance our understanding of mechanisms of heritable neurological disease. ..
  7. EYE MOVEMENTS IN THE PERCEPTION OF DEPTH FROM MOTION
    Mark Nawrot; Fiscal Year: 2002
    ..The addition of an eye movement signal would expand the scope of the model to include motion parallax and its various interactions with binocular stereopsis. ..
  8. MULTIDIMENSIONAL DYNAMIC OF THE VESTIBULO OCULAR REFLEX
    Theodore Raphan; Fiscal Year: 2008
    ..When the study is completed, we will have a quantitative model of how the vestibular system contributes to maintenance of binocular gaze stability while moving. ..
  9. Building a New Model for Diagnosis of ED Dizzy Patients
    David Newman Toker; Fiscal Year: 2007
    ..This research project and the research paradigms derived from it will form the nucleus of a career devoted to research in medical decision-making, causes of diagnostic errors, and methods to preventthem. ..
  10. Short-Latency Disparity Vergence in Strabismic Subjects
    Dongsheng Yang; Fiscal Year: 2006
    ..The rapid, reflex-like nature allows objective assessments of binocular function for potentially all age subjects since active visual attention is not required and promises for future studying of the development of binocular vision. ..
  11. Clinical Trial for Tinnitus Retraining Therapy(TRT)
    C Formby; Fiscal Year: 2002
    ....
  12. MRI, MIT, and MRS of MPS VII and Krabbe Disease
    Charles Vite; Fiscal Year: 2003
    ..x0a; ..
  13. VESTIBULAR MECHANISMS IN THE DYNAMICS OF LOCOMOTION
    Theodore Raphan; Fiscal Year: 2006
    ....
  14. Central Neuronal Activity in Vestibular Compensation
    SHAWN NEWLANDS; Fiscal Year: 2009
    ..This research is an outgrowth of the P.l.'s interest in vestibular compensation developed from his previous research experience and from his work as an otolaryngologist treating patients complaining of dizziness. ..