Genomes and Genes
Summary: The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).
Publications402 found, 100 shown here
- The kappa statistic in reliability studies: use, interpretation, and sample size requirementsJulius Sim
Primary Care Sciences Research Centre, Keele University, Keele, Staffordshire ST5 5BG, United Kingdom
Phys Ther 85:257-68. 2005..This article examines and illustrates the use and interpretation of the kappa statistic in musculoskeletal research...
- Understanding interobserver agreement: the kappa statisticAnthony J Viera
Robert Wood Johnson Clinical Scholars Program, University of North Carolina, USA
Fam Med 37:360-3. 2005..A limitation of kappa is that it is affected by the prevalence of the finding under observation. Methods to overcome this limitation have been described...
- When to use agreement versus reliability measuresHenrica C W de Vet
Institute for Research in Extramural Medicine, VU University Medical Center, Amsterdam, Van der Boechorststraat 7, Amsterdam 1081 BT, The Netherlands
J Clin Epidemiol 59:1033-9. 2006..Consequently, reliability parameters are highly dependent on the heterogeneity of the study sample, while the agreement parameters, based on measurement error, are more a pure characteristic of the measurement instrument...
- Myocardial edema as detected by pre-contrast T1 and T2 CMR delineates area at risk associated with acute myocardial infarctionMartin Ugander
Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
JACC Cardiovasc Imaging 5:596-603. 2012..The aim of this study was to determine whether cardiac magnetic resonance (CMR) in vivo T1 mapping can measure myocardial area at risk (AAR) compared with microspheres or T2 mapping CMR...
- Simultaneous truth and performance level estimation (STAPLE): an algorithm for the validation of image segmentationSimon K Warfield
Harvard Medical School and the Department of Radiology of Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
IEEE Trans Med Imaging 23:903-21. 2004..STAPLE is straightforward to apply to clinical imaging data, it readily enables assessment of the performance of an automated image segmentation algorithm, and enables direct comparison of human rater and algorithm performance...
- Anthropometric measurement error and the assessment of nutritional statusS J Ulijaszek
Institute of Biological Anthropology, University of Oxford, UK
Br J Nutr 82:165-77. 1999..Anthropometry is an important tool for nutritional assessment, and the techniques reported here should allow increased precision of measurement, and improved interpretation of anthropometric data...
- Prediction of all-cause mortality from global longitudinal speckle strain: comparison with ejection fraction and wall motion scoringTony Stanton
School of Medicine, University of Queensland, Brisbane, Australia
Circ Cardiovasc Imaging 2:356-64. 2009..The aim of this study was to compare global longitudinal speckle strain (GLS), an automated technique for measurement of long-axis function, with EF and WMSI for the prediction of mortality...
- Observer variation in immunohistochemical analysis of protein expression, time for a change?T Kirkegaard
Endocrine Cancer Group, Division of Cancer Studies and Molecular Pathology, University Department of Surgery, Glasgow Royal Infirmary, Glasgow, UK
Histopathology 48:787-94. 2006..Interobserver variation is rarely analysed despite recognition that this is a key area of potential inaccuracy. Therefore our aim was to examine observer variation and suggest the revision of current standards.
- Inter-observer reproducibility of HER2 immunohistochemical assessment and concordance with fluorescent in situ hybridization (FISH): pathologist assessment compared to quantitative image analysisGulisa Turashvili
Molecular Oncology and Breast Cancer Program, British Columbia Cancer Research Centre, Vancouver, BC, Canada
BMC Cancer 9:165. 2009..Our study compares HER2 scoring by histopathologists with automated quantitation of staining, and determines the concordance of IHC scores with FISH results...
- Measurement of observer agreementHarold L Kundel
Department of Radiology and MCP Hahnemann School of Public Health, University of Pennsylvania Medical Center, 3600 Market St, Suite 370, Philadelphia, PA 19104, USA
Radiology 228:303-8. 2003..Other measures of agreement that are used less frequently, including multiple-rater kappa, are referenced and described briefly...
- Small (≤ 2 cm) hepatocellular carcinoma in patients with chronic liver disease: comparison of gadoxetic acid-enhanced 3.0 T MRI and multiphasic 64-multirow detector CTJ Hwang
Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
Br J Radiol 85:e314-22. 2012..0 T with that of multiphasic 64-multirow detector CT (MDCT) for the detection of small (≤2 cm) hepatocellular carcinoma (HCC) in patients with chronic liver disease...
- Observer variation in the sonographic measurement of optic nerve sheath diameter in normal adultsS A Ballantyne
Department of Radiology and Clinical Physics, Royal Hospital for Sick Children, G46 7PD, Glasgow, UK
Eur J Ultrasound 15:145-9. 2002To quantify the observer variation in the sonographic measurement of optic nerve sheath diameter (ONSD) in normal adults.
- Global and regional left ventricular myocardial deformation measures by magnetic resonance feature tracking in healthy volunteers: comparison with tagging and relevance of genderDaniel Augustine
Department of Cardiovascular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK
J Cardiovasc Magn Reson 15:8. 2013..We used it to record deformation parameters in healthy adults and compared values to those obtained by tagging...
- Variability in small bowel histopathology reporting between different pathology practice settings: impact on the diagnosis of coeliac diseaseCarolina Arguelles-Grande
Celiac Disease Center at Columbia University Medical Center, Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, New York, New York, USA
J Clin Pathol 65:242-7. 2012..This study evaluated the agreement in biopsy interpretation between different pathology practice types...
- Interobserver and intraobserver variability in interpretation of lumbar disc abnormalities. A comparison of two nomenclaturesM N Brant Zawadzki
Hoag Memorial Hospital, Newport Beach, California, USA
Spine (Phila Pa 1976) 20:1257-63; discussion 1264. 1995..CONCLUSIONS. Experienced readers using standardized nomenclature showed moderate to substantial agreement with interpreting disc extension beyond the interspace on magnetic resonance imaging...
- A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluationR Graham Barr
Division of Radiology, National Jewish Health, Denver, CO 80206, USA
COPD 9:151-9. 2012....
- The impact of gross tumor volume (GTV) and clinical target volume (CTV) definition on the total accuracy in radiotherapy theoretical aspects and practical experiencesElisabeth Weiss
Department of Radiation Therapy, University of Gottingen, Germany
Strahlenther Onkol 179:21-30. 2003..To evaluate the impact of interobserver variability in the contouring of gross tumor volumes (GTVs) and clinical target volumes (CTVs) on the global geometric accuracy in radiation therapy...
- Reliability of photogrammetry in the evaluation of the postural aspects of individuals with structural scoliosisKaren Ruggeri Saad
School of Medicine, Vale do São Francisco Federal University, Av José de Sá Maniçoba, Petrolina PE 56304 917, Brazil
J Bodyw Mov Ther 16:210-6. 2012..The purpose of this study was to investigate the reliability of photogrammetry in the measurement of the postural deviations in individuals with idiopathic scoliosis...
- Inter-examiner reproducibility of tests for lumbar motor controlFlemming Enoch
Department of Rheumatology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
BMC Musculoskelet Disord 12:114. 2011..This has not been considered before. The aim was to analyse the reproducibility of five different quantitative tests for LMC commonly used in daily clinical practice...
- Comparison between cardiovascular magnetic resonance and transthoracic Doppler echocardiography for the estimation of effective orifice area in aortic stenosisJulio Garcia
Quebec Heart and Lung Institute, Laval University, Quebec, Canada
J Cardiovasc Magn Reson 13:25. 2011..Cardiovascular magnetic resonance (CMR) has emerged as an alternative method for non-invasive estimation of valve EOA. The objective of this study was to assess the concordance between TTE and CMR for the estimation of valve EOA...
- Reproducibility of quantitative optical coherence tomography for stent analysisNieves Gonzalo
Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands
EuroIntervention 5:224-32. 2009..To assess the inter- and intra- observer reproducibility for strut count, strut apposition and strut tissue coverage measurements with optical coherence tomography (OCT)...
- The limits of agreement and the intraclass correlation coefficient may be inconsistent in the interpretation of agreementCristina Costa-Santos
Biostatistics and Medical Informatics Department, Faculty of Medicine, University of Porto, Porto, Portugal
J Clin Epidemiol 64:264-9. 2011..To compare the interpretation of agreement in the prediction of neonatal outcome variables, using the limits of agreement (LA) and the intraclass correlation coefficient (ICC)...
- Lymphovascular invasion in colorectal cancer: an interobserver variability studyElizabeth I Harris
Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
Am J Surg Pathol 32:1816-21. 2008..This study was undertaken to examine such interobserver variability, and we hypothesized that the use of immunohistochemical markers for vascular and lymphatic channels could improve interobserver agreement...
- Inter-rater reliability of manual muscle strength testing in ICU survivors and simulated patientsEddy Fan
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 1830 East Monument Street, 5th Floor, Baltimore, MD 21205, USA
Intensive Care Med 36:1038-43. 2010..The goal of the paper is to determine inter-rater reliability of trained examiners performing standardized strength assessments using manual muscle testing (MMT)...
- Magnetic resonance imaging and magnetic resonance arthrography of the shoulder: dependence on the level of training of the performing radiologist for diagnostic accuracyJohn S Theodoropoulos
Division of Orthopaedics, Mount Sinai Hospital and the University Health Network, University of Toronto, Room 476c, 600 University Avenue, Toronto, ON, M5G 1X5, Canada
Skeletal Radiol 39:661-7. 2010..The purpose of this study was to evaluate the diagnostic performance of MR imaging examinations of the shoulder with regard to the training level of the performing radiologist...
- Phantom study on radiotherapy planning using PET/CT--delineation of GTV by evaluating SUVFumiaki Uto
Department of Radiology, Takai Hospital, Nara 632 0006, Japan
J Radiat Res 51:157-64. 2010..An SUV of 40-50% of the maximum is suggested to be appropriate for GTV contouring of sphere tumors with homogenously distributed (18)F-FDG...
- Evaluation of a new carotid intima-media thickness measurement by B-mode ultrasonography using an innovative measurement software, intimascopeToshihiko Yanase
Department of Medicine and Bioregulatory Science, Third Department of Internal Medicine, Graduate School of Medical Sciences, Kyushu University, Maidashi, Fukuoka, Japan
Am J Hypertens 19:1206-12. 2006..Carotid aver-IMT measurement using the new Intimascope software may provide a more precise and reproducible index of atherosclerosis than does conventional IMT measurement...
- Duodenal intraepithelial lymphocyte-count revisitedB Veress
Dept of Pathology, University Hospital MAS, Malmo, Sweden
Scand J Gastroenterol 39:138-44. 2004..The number of intraepithelial lymphocytes in the duodenum was determined 30 years ago, the suggested normal upper limit being 40 lymphocytes per 100 epithelial cells...
- Digital breast tomosynthesis: observer performance studyDavid Gur
Radiology Imaging Research, Department of Radiology, University of Pittsburgh, 3362 Fifth Ave, Rm 223 FARP Bldg, Pittsburgh, PA 15213, USA
AJR Am J Roentgenol 193:586-91. 2009..The purpose of this study was to compare in a retrospective observer study the diagnostic performance of full-field digital mammography (FFDM) with that of digital breast tomosynthesis...
- Prostate cancer: body-array versus endorectal coil MR imaging at 3 T--comparison of image quality, localization, and staging performanceStijn W T P J Heijmink
Department of Radiology, Radboud University Nijmegen Medical Centre, Geert Grooteplein zuid 10, NL 6500 HB, Nijmegen, The Netherlands
Radiology 244:184-95. 2007....
- Accuracy of PET for diagnosis of solid pulmonary lesions with 18F-FDG uptake below the standardized uptake value of 2.5Yaichiro Hashimoto
Division of Nuclear Medicine, Department of Radiology, School of Medicine, Tokyo Women s Medical University, Tokyo, Japan
J Nucl Med 47:426-31. 2006..5. However, the frequency of malignancies with an SUV of <2.5 is significant, and pulmonary nodules with low 18F-FDG uptake often present diagnostic challenges...
- Reliability of malaria microscopy in epidemiological studies: results of quality controlA H Kilian
Basic Health Services Project, Gesellschaft für Technische Zusammenarbeit mbH GTZ, Fort Portal, Uganda
Trop Med Int Health 5:3-8. 2000..Care must be taken, however, when individual parasite density is related to other explanatory variables, due to the high degree of variability in the parasite enumeration...
- Computer recognition of regional lung disease patternsR Uppaluri
Department of Electrical and Computer Engineering and Radiology, Divison of Pulmonary, Department of Internal Medicine, The University of Iowa, Iowa City, Iowa, USA
Am J Respir Crit Care Med 160:648-54. 1999..62. For regional tissue characterization, the AMFM is 100% reproducible and performs as well as experienced human observers who have been told the patient diagnosis...
- Clinical validation of atlas-based auto-segmentation of multiple target volumes and normal tissue (swallowing/mastication) structures in the head and neckDavid N Teguh
Department of Radiation Oncology, Erasmus Medical Center, Rotterdam, The Netherlands
Int J Radiat Oncol Biol Phys 81:950-7. 2011..To validate and clinically evaluate autocontouring using atlas-based autosegmentation (ABAS) of computed tomography images...
- Reliability and sensitivity to change of the OMERACT rheumatoid arthritis magnetic resonance imaging score in a multireader, longitudinal settingEspen A Haavardsholm
Department of Rhumatology, Diakonhjemmet Hospital, Oslo, Norway
Arthritis Rheum 52:3860-7. 2005....
- Lung cancer: interobserver agreement on interpretation of pulmonary findings at low-dose CT screeningDavid S Gierada
Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Blvd, St Louis, MO 63105, USA
Radiology 246:265-72. 2008..To evaluate agreement among radiologists on the interpretation of pulmonary findings at low-dose computed tomographic (CT) screening examinations for lung cancer...
- Prodromal assessment with the structured interview for prodromal syndromes and the scale of prodromal symptoms: predictive validity, interrater reliability, and training to reliabilityTandy J Miller
Yale University, New Haven, CT, USA
Schizophr Bull 29:703-15. 2003..It also presents data suggesting that excellent interrater reliability can be established for diagnosis in a day-and-a-half-long training workshop...
- Sexing skulls using discriminant function analysis of visually assessed traitsPhillip L Walker
Department of Anthropology, University of California, Santa Barbara, California 93106, USA
Am J Phys Anthropol 136:39-50. 2008..Because of such population differences, discriminant functions like those presented in this paper should be used with caution on populations other than those for which they were developed...
- Anaesthetists' Non-Technical Skills (ANTS): evaluation of a behavioural marker systemG Fletcher
Department of Psychology, University of Aberdeen, King s College, UK
Br J Anaesth 90:580-8. 2003..A prototype behavioural marker system was developed using human factors research techniques. The aim of this study was to conduct an experimental evaluation to establish its basic psychometric properties and usability...
- Are proxy assessments of health status after stroke with the EuroQol questionnaire feasible, accurate, and unbiased?P J Dorman
Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, UK
Stroke 28:1883-7. 1997..A proxy, such as a family member or caregiver, may be able to give an estimate of the patients' health status. We therefore examined the agreement between the HRQoL as assessed by a series of patients and that assessed by their proxies...
- Inter-observer variation in the assessment of clinical signs in sick Tanzanian childrenE Kahigwa
Ifakara Health Research and Development Centre, P O Box 53, Ifakara, Tanzania
Trans R Soc Trop Med Hyg 96:162-6. 2002..The difficulties surrounding the diagnosis of impaired consciousness in young children should increase vigilance in the diagnosis and management of neurological complications of illnesses in infancy...
- Error rates in buccal-dental microwear quantification using scanning electron microscopyJ Galbany
Secc Antropologia, Department Biologia Animal, Universitat de Barcelona, Barcelona, Spain
Scanning 27:23-9. 2005..The substitution of semiautomatic with fully automated procedures will completely avoid interobserver error rate differences...
- Reader agreement studiesPhilip E Crewson
Health Services Research and Development Service 124, Department of Veterans Affairs, 810 Vermont Ave, NW, Washington, DC 20420, USA
AJR Am J Roentgenol 184:1391-7. 2005
- Analysis and comparison of the psychometric properties of three balance measures for stroke patientsHui Fen Mao
School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC
Stroke 33:1022-7. 2002....
- The need for treatment and satisfaction with dental appearance among young Finnish adults with and without a history of orthodontic treatmentH Kerosuo
Department of Pedodontics and Orthodontics, University of Helsinki, Finland
J Orofac Orthop 61:330-40. 2000..The high treatment rate in relation to unnoticed treatment need calls for reevaluation of priorities in patient selection...
- Agreement and repeatability of central thickness measurement in normal corneas using ultrasound pachymetry and the OCULUS PentacamClare O'Donnell
Faculty of Life Sciences, The University of Manchester, UK
Cornea 24:920-4. 2005..To compare the accuracy and repeatability of the OCULUS Pentacam (a new Scheimpflug-based imaging system) with ultrasound pachymetry in the measurement of central corneal thickness (CCT)...
- Accuracy and repeatability of cone-beam computed tomography (CBCT) measurements used in the determination of facial indices in the laboratory setupBernard A M M L Moerenhout
Division of Maxillo Facial Surgery, Department of Surgery, General Hospital St Jan, Bruges, Belgium
J Craniomaxillofac Surg 37:18-23. 2009..V., Mechelen, Belgium)...
- Evaluation of intraexaminer and interexaminer agreement on classifying lower third molars according to the systems of Pell and Gregory and of WinterNieves Almendros-Marqués
Oral and Maxillofacial Surgery, Barcelona University Dental School, Barcelona, Spain
J Oral Maxillofac Surg 66:893-9. 2008....
- Observer reliability of three-dimensional cephalometric landmark identification on cone-beam computerized tomographyAna Emilia F de Oliveira
Department of Dentistry I, Universidade Federal do Maranhao, Maranhao, Brazil
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107:256-65. 2009..To evaluate reliability in 3-dimensional (3D) landmark identification using cone-beam computerized tomography (CBCT)...
- The accuracy and reliability of measurements made on computer-based digital modelsMeredith L Quimby
Section of Orthodontics, College of Dentistry, The Ohio State University, Columbus, Ohio 43210, USA
Angle Orthod 74:298-303. 2004..Efficacy and effectiveness were similar to those of plaster models. Therefore, computer-based models appear to be a clinically acceptable alternative to conventional plaster models...
- A comparison between 2D and 3D cephalometry on CBCT scans of human skullsO J C van Vlijmen
3 D Facial Imaging Research Group Nijmegen Bruges, The Netherlands
Int J Oral Maxillofac Surg 39:156-60. 2010..The authors recommend that 3D tracings for longitudinal research are not used in cases were there are only 2D records from the past...
- The prognostic impact of TGF-β1, fascin, NF-κB and PKC-ζ expression in soft tissue sarcomasAndrej Valkov
Department of Clinical Pathology, University Hospital of Northern Norway, Tromsø, Norway
PLoS ONE 6:e17507. 2011..We aimed to investigate the prognostic impact of TGF-β1, NF-κB p105, PKC-ζ, Par-6α, E-cadherin and vimentin in non-gastrointestinal stromal tumor soft tissue sarcomas (non-GIST STSs)...
- Orthodontic treatment need in French schoolchildren: an epidemiological study using the Index of Orthodontic Treatment NeedMourad Souames
Department of Epidémiologie Prévention Economie de la santé Paris University 7, France
Eur J Orthod 28:605-9. 2006..The dental health component (DHC) of the IOTN was found to be reliable and simple to use. The malocclusion status of French schoolchildren was lower than that recorded in epidemiological studies of European children...
- Inter-observer variability in APACHE II scoring: effect of strict guidelines and trainingK H Polderman
Surgical Intensive Care Unit, University Hospital Vrije Universiteit, P O Box 7057, 1007 MB Amsterdam, The Netherlands
Intensive Care Med 27:1365-9. 2001..To assess the effect of strict guidelines and a rigorous training program on variability in scoring the revised Acute Physiology and Chronic Health Evaluation (APACHE II)...
- Radiographic evaluation of the hip has limited reliabilityJohn C Clohisy
Department of Orthopaedic Surgery, Washington University School of Medicine, One Barnes Hospital Plaza, Suite 11300 West Pavilion, Campus Box 8233, St Louis, MO 63110, USA
Clin Orthop Relat Res 467:666-75. 2009..Accordingly, a more clear set of definitions and measurements must be developed to allow for more reliable diagnosis of early hip disease...
- Tilt and rotation correction of acetabular version on pelvic radiographsM Tannast
Department of Orthopaedic Surgery, Inselspital, University of Bern, Bern, Switzerland
Clin Orthop Relat Res 438:182-90. 2005..The computer-assisted method allows standardized evaluation of anatomic morphologic differences of femoral coverage (dysplasia, retroversion), making their clinical relevance for development of early osteoarthritis more valuable...
- Assessment of young children using the Achenbach System of Empirically Based Assessment (ASEBA)Leslie A Rescorla
Department of Psychology, Bryn Mawr College, Bryn Mawr, PA 19010 2988, USA
Ment Retard Dev Disabil Res Rev 11:226-37. 2005..Clinical and research applications of ASEBA preschool forms are summarized in the paper, and strengths and limitations are discussed...
- Accuracy and concordance of nurses in emergency department triageKatarina Göransson
Department of Health Sciences, Orebro University, Sweden
Scand J Caring Sci 19:432-8. 2005..46 (unweighted) and kappa = 0.71 (weighted). The fact that the kappa-values are only moderate to good and the low concordance between the RNs call for further studies, especially from a patient safety perspective...
- Can ultrasonography improve on radiographic assessment in osteoarthritis of the hands? A comparison between radiographic and ultrasonographic detected pathologyH I Keen
Academic Unit of Musculoskeletal Disease, Chapel Allerton Hospital, Chapeltown Road, Leeds LS7 4SA, UK
Ann Rheum Dis 67:1116-20. 2008..This study aimed to compare the detection of osteophytosis and joint space narrowing (JSN) by US and conventional radiography (CR) in OA of the hand...
- An admissions OSCE: the multiple mini-interviewKevin W Eva
Department of Clinical Epidemiology and Biostatistics, Programme for Educational Research and Development, McMaster University, Hamilton, Ontario, Canada
Med Educ 38:314-26. 2004....
- (18)F-FDG PET-CT simulation for non-small-cell lung cancer: effect in patients already staged by PET-CTGerard G Hanna
Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Belfast, Northern Ireland, United Kingdom
Int J Radiat Oncol Biol Phys 77:24-30. 2010..In previously PET-CT staged patients with NSCLC, we assessed the effect of using an additional planning PET-CT scan for gross tumor volume (GTV) definition...
- How to perform an accurate assessment of cardiac function in mice using high-resolution magnetic resonance imagingJurgen E Schneider
Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, UK
J Cardiovasc Magn Reson 8:693-701. 2006..Here, we describe a protocol that allows for a quick and reproducible approach of obtaining the relevant cardiac views for cine-MRI, and we explain how an accurate experimental image analysis can be performed...
- Radiation dose reduction with chest computed tomography using adaptive statistical iterative reconstruction technique: initial experiencePriyanka Prakash
Division of Thoracic Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
J Comput Assist Tomogr 34:40-5. 2010..To assess radiation dose reduction and image quality for weight-based chest computed tomographic (CT) examination results reconstructed using adaptive statistical iterative reconstruction (ASIR) technique...
- Evaluation of automatic atlas-based lymph node segmentation for head-and-neck cancerLiza J Stapleford
Department of Radiation Oncology, Emory University School of Medicine and Winship Cancer Institute of Emory University, Atlanta, GA 30322, USA
Int J Radiat Oncol Biol Phys 77:959-66. 2010..To evaluate if automatic atlas-based lymph node segmentation (LNS) improves efficiency and decreases inter-observer variability while maintaining accuracy...
- Measuring the similarity of target volume delineations independent of the number of observersErik Kouwenhoven
Department of Medical Physics, Medical Center Haaglanden, 2501 CK The Hague, The Netherlands
Phys Med Biol 54:2863-73. 2009..The use of the third generalization for the CI which is based upon the volume common to all delineations shows a clear dependence upon the number of delineations and is discouraged...
- The Strengths and Difficulties Questionnaire in the Nordic countriesCarsten Obel
Perinatal Epidemiological Research Unit, Dept Gynaecology and Obstetrics, Aarhus University Hospital, Skejby, 8200, Aarhus N, Denmark
Eur Child Adolesc Psychiatry 13:II32-9. 2004..The largest studies have been performed in Norway and Denmark, and in these countries the diagnostic interview DAWBA has also been used in conjunction with the SDQ...
- Inter-observer and intra-observer reliability for lung cancer target volume delineation in the 4D-CT eraAlexander V Louie
Department of Radiation Oncology, London Regional Cancer Program, London, Ont, Canada
Radiother Oncol 95:166-71. 2010..To investigate inter-observer and intra-observer target volume delineation (TVD) error in 4D-CT imaging of thoracic tumours...
- Chest radiograph reading and recording system: evaluation for tuberculosis screening in patients with advanced HIVR Dawson
University of Cape Town Lung Institute, Division of Pulmonology and E16 Respiratory Clinic, Groote Schuur Hospital, Cape Town, South Africa
Int J Tuberc Lung Dis 14:52-8. 2010..An antiretroviral treatment (ART) service in Gugulethu township, Cape Town, South Africa...
- Variability among breast radiation oncologists in delineation of the postsurgical lumpectomy cavityDaniel M Landis
Joint Center for Radiation Therapy Residency Training Program, Harvard Medical School, Brigham and Women s Hospital, Boston, MA, USA
Int J Radiat Oncol Biol Phys 67:1299-308. 2007..We examined the interobserver variability in delineation of the lumpectomy cavity among four academic radiation oncologists who specialize in the treatment of breast cancer...
- Are diagnostic criteria for general joint hypermobility and benign joint hypermobility syndrome based on reproducible and valid tests? A review of the literatureLars Remvig
Clinic of Orthopaedic Medicine and Rehabilitation, Rigshospitalet, Copenhagen University, Denmark
J Rheumatol 34:798-803. 2007..In this review we focus on current knowledge of the reliability of tests and diagnostic criteria for generalized joint hypermobility (GJH) and benign joint hypermobility syndrome (BJHS)...
- How precise can bony landmarks be determined on a CT scan of the knee?J Victor
AZ St Lucas, Brugge, Belgium
Knee 16:358-65. 2009..In the tibia, the best result is obtained for the tibial transverse axis...
- EQ-5D in patients with dementia: an investigation of inter-rater agreementW Coucill
Health Economics Facility, University of Birmingham, England, UK
Med Care 39:760-71. 2001..There are difficulties in obtaining health-related quality of life (HRQL) data from patients with dementia due to variation in their cognitive ability, degree of insight and capacity to make judgments. The use of proxies is one solution...
- Direct T2 quantification of myocardial edema in acute ischemic injuryDavid Verhaert
The Ohio State University, Columbus, Ohio 43210, USA
JACC Cardiovasc Imaging 4:269-78. 2011..To evaluate the utility of rapid, quantitative T2 mapping compared with conventional T2-weighted imaging in patients presenting with various forms of acute myocardial infarction...
- Bright-blood T2-weighted MRI has higher diagnostic accuracy than dark-blood short tau inversion recovery MRI for detection of acute myocardial infarction and for assessment of the ischemic area at risk and myocardial salvageAlexander R Payne
West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Glasgow, Scotland, United Kingdom
Circ Cardiovasc Imaging 4:210-9. 2011..We compared the diagnostic accuracy of a new bright-blood T2-weighted with a standard black blood T2-weighted MRI in patients with acute MI...
- Psychometric properties of the parent and teacher versions of the strengths and difficulties questionnaire for 4- to 12-year-olds: a reviewLisanne L Stone
Behavioural Science Institute, Radboud University Nijmegen, P O Box 9104, 6500 HE Nijmegen, The Netherlands
Clin Child Fam Psychol Rev 13:254-74. 2010..Longitudinal research studies should investigate predictive validity. For both practice and research, we emphasize the use of a multi-informant approach...
- Speckle-tracking echocardiography correctly identifies segmental left ventricular dysfunction induced by scarring in a rat model of myocardial infarctionZoran B Popovic
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Am J Physiol Heart Circ Physiol 292:H2809-16. 2007..0001) than on percent fibrosis (P<0.002). STE correctly identifies segmental LV dysfunction induced by scarring that follows myocardial infarction in rats...
- A randomised controlled trial of the efficacy of supervised toothbrushing in high-caries-risk childrenM M T Curnow
Tayside NHS Primary Care Trust, Dental Department, Drumhar Health Centre, Perth, Scotland, UK
Caries Res 36:294-300. 2002..In conclusion, high-caries-risk children have been shown to have significantly less caries after participating in a supervised toothbrushing programme with a fluoridated toothpaste...
- Variability in interpretation of chest radiographs among Russian clinicians and implications for screening programmes: observational studyY Balabanova
Health Protection Agency National Mycobacterium Reference Unit, Department of Microbiology and Infection, Guy s, King s, and St Thomas Medical School, London
BMJ 331:379-82. 2005..To determine variability in interpretation of chest radiographs among tuberculosis specialists, radiologists, and respiratory specialists...
- Comparison of two-dimensional speckle and tissue velocity based strain and validation with harmonic phase magnetic resonance imagingGoo Yeong Cho
Department of Medicine, University of Queensland, Brisbane, Australia
Am J Cardiol 97:1661-6. 2006..Nonetheless, epsilon2-D provides a reliable tool to quantify regional function, with radial measurements being more accurate and feasible than with TVI. Unlike epsilonTVI, epsilon2-D provides circumferential measurements...
- Accuracy of echocardiographic estimates of left ventricular mass in miceK A Collins
Noninvasive Cardiac Imaging Laboratory, University of Chicago, Chicago, Illinois 60637, USA
Am J Physiol Heart Circ Physiol 280:H1954-62. 2001....
- Reproducibility of MRI measurements of right ventricular size and function in patients with normal and dilated ventriclesChristiaan F Mooij
Department of Cardiology, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
J Magn Reson Imaging 28:67-73. 2008..To determine the inter- and intraobserver reproducibility of cardiac magnetic resonance (CMR)-derived measurements of right ventricular (RV) mass, volume, and function in patients with normal and dilated ventricles...
- Proliferating cell nuclear antigen and Ki67 immunoreactivity in ameloblastomasShabnum Meer
University of the Witwatersrand, Division of Oral Pathology, Department of Anatomical Pathology, South Africa
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95:213-21. 2003....
- T2 relaxation time of cartilage at MR imaging: comparison with severity of knee osteoarthritisTimothy C Dunn
Department of Radiology, University of California at San Francisco, 185 Berry St, Suite 350, San Francisco, CA 94107 1739, USA
Radiology 232:592-8. 2004....
- Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU)E W Ely
Department of Internal Medicine, Divisions of General Internal Medicine and Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN, USA
Crit Care Med 29:1370-9. 2001..To develop and validate an instrument for use in the intensive care unit to accurately diagnose delirium in critically ill patients who are often nonverbal because of mechanical ventilation...
- Sonographic features of benign thyroid nodules: interobserver reliability and overlap with malignancyJeffrey R Wienke
Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
J Ultrasound Med 22:1027-31. 2003..To prospectively determine the sonographic findings of nodular hyperplasia of the thyroid, to compare these with reported findings associated with malignancy, and to assess interobserver reliability...
- Consistency and precision of landmark identification in three-dimensional cone beam computed tomography scansWill Schlicher
Division of Orthodontics, Department of Orofacial Sciences, School of Dentistry, University of California at San Francisco, San Francisco, CA 94143 0438, USA
Eur J Orthod 34:263-75. 2012..The most inconsistent landmark was porion-right (2.72 mm) and the most imprecise landmark was orbitale-right (1.81 mm). Due to the lack of even distribution of the errors, careful use of these landmarks for analysis purposes is needed...
- Intraobserver and interobserver agreement of the interpretation of pediatric chest radiographsJeremiah Johnson
Department of Emergency Medicine, Brooke Army Medical Center, 3851 Roger Brooke Dr, Fort Sam Houston San Antonio, TX, 78234, USA
Emerg Radiol 17:285-90. 2010..37 (0.25-0.51). Practicing emergency clinicians demonstrate considerable intraobserver and interobserver variability in the interpretation of pneumonia on pediatric chest radiographs...
- Prostate cancer: apparent diffusion coefficient map with T2-weighted images for detection--a multireader studyHyun Kyung Lim
Department of Radiology, Asan Medical Center, University of Ulsan, 388 1 Poongnap dong, Songpa Gu, Seoul, 138 736, South Korea
Radiology 250:145-51. 2009....
- Interobserver agreement for sonograms of breast lesions obtained by an automated breast volume scannerJing Zhang
Department of Diagnostic Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No 1 Shuaifuyuan, Dongcheng District, Beijing 100730, China
Eur J Radiol 81:2179-83. 2012....
- Variability of semiautomated lung nodule volumetry on ultralow-dose CT: comparison with nodule volumetry on standard-dose CTPatrick A Hein
Department of Radiology, Charite Campus Mitte, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Germany
J Digit Imaging 23:8-17. 2010..Thus, the evaluated segmentation software provides nodule volumetry that appears to be independent of the dose level with which the CT source dataset is acquired...
- Use of the Alberta Stroke Program Early CT Score (ASPECTS) for assessing CT scans in patients with acute strokeJ H Pexman
Department of Clinical Neurosciences, Foothills Hospital, Calgary, Alberta, Canada
AJNR Am J Neuroradiol 22:1534-42. 2001..CONCLUSION: ASPECTS is a systematic, robust, and practical method that can be applied to different axial baselines. Clinician agreement is superior to that of the 1/3 MCA rule...
- The contribution of integrated PET/CT to the evolving definition of treatment volumes in radiation treatment planning in lung cancerHani Ashamalla
Department of Radiation Oncology, New York Methodist Hospital, Weill Medical College of Cornell University, Brooklyn, NY 11215, USA
Int J Radiat Oncol Biol Phys 63:1016-23. 2005....
- Intraobserver and interobserver reproducibility in the evaluation of ultrasonic pachymetry measurements of central corneal thicknessS Miglior
Department of Ophthalmology, University of Milan Bicocca, Department of Neurosciences and Biomedical Technologies, Via Cadore 48, 20052 Monza, Milan, Italy
Br J Ophthalmol 88:174-7. 2004..To assess reproducibility of central corneal thickness (CCT) measurement by means of ultrasonic pachymetry...
- The Irvine-Minnesota inventory to measure built environments: reliability testsMarlon G Boarnet
Department of Planning, Policy, and Design, University of California Irvine, Irvine, California, USA
Am J Prev Med 30:153-159. 2006..This paper presents results of reliability tests of the Irvine-Minnesota Inventory, an extensive audit tool aimed at measuring a broad range of built environment features that may be linked to active living...
- Interobserver variability in the CT assessment of honeycombing in the lungsTakeyuki Watadani
Dept of Diagnostic Radiology, Saitama International Medical Ctr, Saitama Medical Univ, Hidaka, Saitama 3501298, Japan
Radiology 266:936-44. 2013..To quantify observer agreement and analyze causes of disagreement in identifying honeycombing at chest computed tomography (CT)...
- Fully automatic segmentation of white matter hyperintensities in MR images of the elderlyF Admiraal-Behloul
Department of Radiology, C2S, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands
Neuroimage 28:607-17. 2005....
- Impact of papillary muscles in ventricular volume and ejection fraction assessment by cardiovascular magnetic resonanceBurkhard Sievers
Department of Cardiology and Angiology, University of Bochum, Hölkeskampring 40, D 44625 Herne, Germany
J Cardiovasc Magn Reson 6:9-16. 2004..Not subtracting the volumes of these structures enables faster determination of right and left ventricular volumes and ejection fractions without loss of the accuracy associated with the standard short-axis technique...
- Real-time 3-dimensional echocardiographic quantification of left ventricular volumes: multicenter study for validation with magnetic resonance imaging and investigation of sources of errorVictor Mor-Avi
University of Chicago Medical Center, Chicago, Illinois 60637, USA
JACC Cardiovasc Imaging 1:413-23. 2008....
- Improved aortic pulse wave velocity assessment from multislice two-directional in-plane velocity-encoded magnetic resonance imagingJos J M Westenberg
Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands
J Magn Reson Imaging 32:1086-94. 2010..To evaluate the accuracy and reproducibility of aortic pulse wave velocity (PWV) assessment by in-plane velocity-encoded magnetic resonance imaging (MRI)...
- Intra- and inter-observer reliability in anthropometric measurements in childrenS Stomfai
Department of Paediatrics, Medical Faculty, University of Pecs, Hungary
Int J Obes (Lond) 35:S45-51. 2011..Therefore, it is important to confirm that body composition indices, which are subject to intra- and inter-individual variation, are measured using a standardised protocol that maximises their reliability and reduces error in analyses...
- Interobserver variability associated with the MIB-1 labeling index: high levels suggest limited prognostic usefulness for patients with primary brain tumorsD M Grzybicki
Department of Pathology and Laboratory Medicine, Allegheny General Hospital and MCP Hahnemann University, Pittsburgh, Pennsylvania 15212, USA
Cancer 92:2720-6. 2001..However, interobserver variability associated previously with MIB-1 LI calculation has not been reported despite the fact that the degree of interobserver variability impacts the clinical usefulness of such cut-off values...
- Detection of Liver Fibrosis Using IVIM Diffusion and DCE MRI in HCVBachir Taouli; Fiscal Year: 2013..These techniques combined could reach high diagnostic performance for detection of liver fibrosis;and could decrease the number of necessary liver biopsies, which have risks and sample only a small portion of the liver. ..
- FOUR-DIMENSIONAL MRI FOR IMAGE-GUIDED RADIATION THERAPY FOR PANCREATIC CANCERYanle Hu; Fiscal Year: 2013..With reduced uncertainty in tumor location, shape and motion, we will be able to provide more conformal treatments, reducing radiation dose to normal tissues and thus the GI toxicity rate. ..
- Computer-Aided Detection of Pulmonary Embolism on CT Pulmonary AngiographyChuan Zhou; Fiscal Year: 2012..CAD will potentially reduce missed PEs and improve the chance of timely treatment of patients, thus reducing the mortality rate and speed up recovery from this condition. ..
- Quantification of Regional Lung Disease by Computed TomographyCuneyt Yilmaz; Fiscal Year: 2010..End of Abstract) ..
- Accuracy of Breast Pathology and the Impact of Double ReadingDONALD LEE WEAVER; Fiscal Year: 2013..We will then evaluate methods for improving health care delivery using double reading. Finally, we will use a systematic method to make projections from our data to clinical implications of inaccurate diagnoses. ..
- Integrating Quantitative Histological Image and Vascular Density Patterns for ProAnant Madabhushi; Fiscal Year: 2010..Data accrual will be done at UPENN while algorithmic development for computerized image analysis and classification will be carried out at RU. ..
- Automating MRI Delta T1 Methods for the Routine Assessment of Brain Tumor BurdenKATHLEEN MARIE SCHMAINDA; Fiscal Year: 2012..This in turn can result in the performance of more efficient and cost-effective clinical trials, as well as improved care of patients on an individualized basis. ..
- Image Mining for Comparative Analysis of Expression Patterns in Tissue MicroarrayJoel H Saltz; Fiscal Year: 2013....
- Fractional flow reserve measurement based on coronary angiographic imagesSABEE Y MOLLOI; Fiscal Year: 2010..This quantification technique could be used to measure fractional flow reserve in patients undergoing standard coronary arteriography. ..
- Application of QDs-based nanotyping technology in the evaluation of chemotherapyY Andrew Wang; Fiscal Year: 2010..Moreover, IHC remains semi-quantitative and subjective, resulting in considerable inter-observer variation in results...
- Computerized Detection of Polyps in CT ColonographyHiroyuki Yoshida; Fiscal Year: 2009..abstract_text> ..
- Intelligent and Automatic Image Segmentation Software for High ThroughputAnalysiKaryn Esser; Fiscal Year: 2013....
- Novel Nanoscale Single-Cell Analysis of Exfoliative CytologyYang Liu; Fiscal Year: 2013..light microscope limis the detection of mostly micron-scale features of cancer cells, which result in intra-observer variation, missed early-stage cancers (false negatives), and indeterminate cases that often result in unnecessary ..
- QUANTITATIVE CORONARY ANGIOGRAPHY BY DUAL ENERGY DSASabee Molloi; Fiscal Year: 1993..Furthermore, the basic data set from these quantitative techniques can potentially be utilized to derive more physiologically significant parameters such as absolute blood flow or coronary blood flow reserve...
- Computer-Aided Detection of Pulmonary Embolism on CT Pulmonary AngiographyChuan Zhou; Fiscal Year: 2007..CAD will potentially reduce missed PEs and improve the chance of timely treatment of patients, thus reducing the mortality rate and speed up recovery from this condition. [unreadable] [unreadable]..
- THREE DIMENSIONAL CT COLONOGRAPHYChristopher Beaulieu; Fiscal Year: 2007..abstract_text> ..
- STROKE OUTCOME AND NEUROIMAGING OF INTRACRANIAL STENOSISEdward Feldmann; Fiscal Year: 2003..SONIA will use these techniques to develop TCD or MRA cutpoints that minimize the clinical consequences of test errors that occur in the noninvasive evaluation of patients with suspected intracranial atherosclerosis. ..
- ULTRASOUND DETECTION AND STAGING OF PROSTATIC CANCERJoseph Smith; Fiscal Year: 1992..A statistical and coordinating center has been established to record and analyze the results. Serum will be stored in a central bank and prostate specific antigen performed all on patients at a core laboratory...
- Pulmonary Lobar Analysis by 3D Surface DetectionJuerg Tschirren; Fiscal Year: 2007..The proposed methods are urgently needed to take advantage of emerging therapies for the early treatment of lung disease. [unreadable] [unreadable] [unreadable]..
- Quantification of Regional coronary Blood FlowSabee Molloi; Fiscal Year: 2003..This quantification technique could be used to measure regional myocardial perfusion in patients undergoing standard coronary arteriography. ..
- Perception and Inter-Observer Variability in MammographyClaudia Mello Thoms; Fiscal Year: 2005..In addition, the changes in sampling strategy will correspond to actual possible strategies for the human observers themselves. ..
- COMPUTER AIDED DIAGNOSIS IN BREAST IMAGINGMaryellen Giger; Fiscal Year: 2005..We believe that with the combined information from multimodality imaging and clinical information, overall patient outcome will improve. ..
- AUTOMATED QUANTITATION OF 3D ECHOCARDIOGRAMSRichard Johnson; Fiscal Year: 2003..This technology can be included in ultrasound systems or provided in workstations. The core technology can be applied to other organs and other imaging modalities. ..
- Vessel Segmentation/Registration from Ultrasound ImagesSayan Pathak; Fiscal Year: 2003..The goal of the Phase I study is to establish feasibility of the proposed methods by demonstrating an improvement in the repeatability and accuracy of measurements and reduction in delineation time. ..
- Reducing Benign Breast Biopsies with Computer ModelingJay Baker; Fiscal Year: 2006..Assuming performance approaching that of the preliminary model, a decision aid based on this model will be ready for prospective clinical trials at the conclusion of this project. ..
- Content based mammogram retrieval as a diagnostic aidMILES WERNICK; Fiscal Year: 2003..abstract_text> ..
- PERCEPTUAL MODEL FOR WORKSTATION DISPLAY OPTIMIZATIONDev Chakraborty; Fiscal Year: 2003..Also to be generated are iso-contour plots of the effects of common workstation variables on image quality in both tasks. This will allow digital mammography workstations to be more intelligently used. ..
- PERCEPTUAL MODEL FOR WORKSTATION DISPLAY OPTIMIZATIONDev Chakraborty; Fiscal Year: 2002..Also to be generated are iso-contour plots of the effects of common workstation variables on image quality in both tasks. This will allow digital mammography workstations to be more intelligently used. ..
- Conference--Medical Image PerceptionElizabeth Krupinski; Fiscal Year: 2003..This grant will be used to provide financial support for about 12 graduate students and residents, as well as logistic support for publicity and program printing. ..
- The Cardiac Atlas Project: Establishment of a Cardiac MRI Database.ALISTAIR ANDREW YOUNG; Fiscal Year: 2010..By pooling data from many studies into a single resource, researchers will be able to perform standardized comparisons across many patient groups, in order to better predict and evaluate the effects of disease and treatment. ..
- Optimized Compression for Telepathology Virtual SlidesElizabeth Krupinski; Fiscal Year: 2009....
- MIPS XII ConferenceElizabeth Krupinski; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- OPTIMIZING SOFTCOPY DISPLAYS FOR DIGITAL MAMMOGRAPHYElizabeth Krupinski; Fiscal Year: 2002..The JND metrix model will then be used to systematically explore and optimize CRT design tradeoffs for current and future digital-mammography display systems. ..
- Medical Image Perception Society Confrence XIElizabeth Krupinski; Fiscal Year: 2005..abstract_text> ..
- OPTIMIZING SOFTCOPY DISPLAYS FOR DIGITAL MAMMOGRAPHYElizabeth Krupinski; Fiscal Year: 2003..The JND metrix model will then be used to systematically explore and optimize CRT design tradeoffs for current and future digital-mammography display systems. ..
- The ODIE Toolkit - Software for Information Extraction and Biomedical Ontology DeRebecca S Crowley; Fiscal Year: 2010..Additionally, the project would contribute to the software for developing other applications by helping researchers build more comprehensive ontologies. The results of this work may benefit both medical research and patient care. ..
- Capacity to Appoint a Proxy for Research ConsentScott Kim; Fiscal Year: 2009..abstract_text> ..
- Enteric flora modulates the development of colitisAlbert Jergens; Fiscal Year: 2008..g., graduate students and postdoctoral fellow). There are ample opportunities to attend seminars, journal clubs and work-in-progress research meetings during which the applicant can become engaged in scientific discussions. ..
- PROGNOSIS OF CHILDREN WITH A FIRST UNPROVOKED SEIZUREShlomo Shinnar; Fiscal Year: 2002....
- Family Involvement /Resident Psychosocial Status in LTCJOSEPH GAUGLER; Fiscal Year: 2002..abstract_text> ..
- EARLY VOCAL DEVELOPMENT IN YOUNG CHILDREN WITH COCHLEARDAVID ERTMER; Fiscal Year: 2002..18). ..
- An Automated System for Breast Cancer Biomarker AnalysisJohn J Heine; Fiscal Year: 2010..This work will produce a calibrated automated density assessment package that may be easily implemented across institutions without modifications for use in the FFDM systems that is tailored for tissue-related risk research. ..
- PHARYNGEAL AIRWAY FUNCTIONSAMUEL KUNA; Fiscal Year: 2003....
- Manipulating the ProteomeJoshua Labaer; Fiscal Year: 2001..The focus of this Center is to develop a toolkit of technologies that will enable the genome-scale study of protein function. ..
- b-catenin's role in establishing the gut stem cell nicheMelissa Wong; Fiscal Year: 2009..These proposed studies will directly examine the role of Wnt/beta-catenin signaling on maintenance of the stem cell niche and will shed insight into the regulatory control of intestinal stem cells. ..
- Caregiver Outcomes Post NH Placement of a Family MemberJOSEPH GAUGLER; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Speech Production in Phonological ImpairmentBenjamin Munson; Fiscal Year: 2005....
- Multiple Factors Affecting Placebo Response in PDChristopher Goetz; Fiscal Year: 2004..Defining these determinant influences will help enhance placebo responses in clinical practice and control them in clinical trials. ..
- MMP-2 and MMP-9: Colorectal Cancer DiagnosisMary Murnane; Fiscal Year: 2005....
- A Novel Method for Determining Image SimilarityRobert Nishikawa; Fiscal Year: 2006..A reduction in the number of "unnecessary" biopsies will reduce cost, and physical and mental trauma to patients. [unreadable] [unreadable]..
- High-Performance Computer Cluster for Image AnalysisRobert Nishikawa; Fiscal Year: 2007....
- YFLEX: Saccharomyces cerevisiae ORF Clone ResourceJoshua Labaer; Fiscal Year: 2004..abstract_text> ..
- Molecular Dissection of Benign Prostatic HyperplasiaMark Rubin; Fiscal Year: 2004..b) Validation of tissue markers using MTOPS samples. Aim 4: Validation of candidate serum biomarkers of symptomatic BPH. a) Serum Microarray Validation using Michigan samples. b) Validation of serum markers using MTOPS samples. ..
- In search of the intestinal stem cellMelissa Wong; Fiscal Year: 2004..These studies will determine if a signaling cascade is responsible for defining "stemness" or if a yet to be defined master regulator molecule directs synergy of the multiple pathways. ..
- Epidemiology of Carotid Intima-Medial Thickness (IMT) in AtherosclerosisJoseph Polak; Fiscal Year: 2007..unreadable] [unreadable]..
- Disability in Valued Life Activities in Persons with Rheumatoid ArthritisPatricia Katz; Fiscal Year: 2007..unreadable] [unreadable]..
- Multimodality CAD system with image references for breast mass characterizationBerkman Sahiner; Fiscal Year: 2007..Any reduction in this number without a decrease in breast cancer detection sensitivity will decrease health care costs, as well as contribute to the well-being of the patient by reducing anxiety and morbidity. ..
- Clinical Features in Nursing Home Residents with Suspected UTIManisha Juthani Mehta; Fiscal Year: 2008..This study will create an evidence-based definition of UTI. Future studies will identify residents with UTI in whom antibiotic therapy improves clinical outcome. [unreadable] [unreadable] [unreadable]..
- MRI Detection, Lateralization, and Quantification of Mesial Temporal Lobe EpilepsRotem Elgavish; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Low-cost, portable, computer assisted imaging for diabe*Michael Abramoff; Fiscal Year: 2008..Our overall aim is to validate and optimize a low-cost, high quality, patient friendly imaging system for the early diagnosis of diabetic retinopathy. ..
- Computer mediated speech assessment in aphasia and AOSKatarina Haley; Fiscal Year: 2006..These will include clinicians' and everyday listeners' ratings of speech severity, estimation of speaking rate, and frequency of errors identified on broad phonetic transcription. ..
- IRT and Psychological Disturbance in Young OffendersGina Vincent; Fiscal Year: 2005..Indirectly, findings will work toward advancing our misunderstanding of the nature and development of child psychopathology in general. ..
- Development of Improved Earphone for Hearing TestingRobert Margolis; Fiscal Year: 2008..In this project an earphone is being developed that can be used in both automated and manual testing and will significantly increase the efficiency, accuracy, and accessibility. [unreadable] [unreadable] [unreadable]..