pain measurement

Summary

Summary: Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.

Top Publications

  1. ncbi Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations
    Robert H Dworkin
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Pain 9:105-21. 2008
  2. ncbi Acceptance of chronic pain: component analysis and a revised assessment method
    Lance M McCracken
    Pain Management Unit, Royal National Hospital for Rheumatic Diseases and University of Bath, Bath BA1 1RL, UK
    Pain 107:159-66. 2004
  3. ncbi Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment
    Harald Breivik
    University of Oslo, Faculty of Medicine, Faculty Division Rikshospitalet, Department of Anaesthesiology, Rikshospitalet University Hospital, Norway
    Eur J Pain 10:287-333. 2006
  4. ncbi Coding of facial expressions of pain in the laboratory mouse
    Dale J Langford
    Department of Psychology and Alan Edwards Centre for Research on Pain, McGill University, Montreal, Quebec, Canada
    Nat Methods 7:447-9. 2010
  5. ncbi Quantitative assessment of tactile allodynia in the rat paw
    S R Chaplan
    Department of Anesthesiology, University of California, San Diego, La Jolla 92093 0818
    J Neurosci Methods 53:55-63. 1994
  6. ncbi Neuropathic pain: redefinition and a grading system for clinical and research purposes
    R D Treede
    Institute of Physiology and Pathophysiology, Johannes Gutenberg University, Mainz, Germany
    Neurology 70:1630-5. 2008
  7. ncbi Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale
    J T Farrar
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Blockley Hall, Room 816, 423 Guardian Drive, Philadelphia, PA 19104, USA
    Pain 94:149-58. 2001
  8. ncbi Core outcome measures for chronic pain clinical trials: IMMPACT recommendations
    Robert H Dworkin
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Pain 113:9-19. 2005
  9. ncbi A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures
    Rachelle Buchbinder
    Monash Department of Clinical Epidemiology, Cabrini Hospital, and Monash University, Malvern, Vic, Australia
    N Engl J Med 361:557-68. 2009
  10. pmc Sex, gender, and pain: a review of recent clinical and experimental findings
    Roger B Fillingim
    University of Florida, College of Dentistry, Gainesville, Florida 32610 3628, USA
    J Pain 10:447-85. 2009

Detail Information

Publications285 found, 100 shown here

  1. ncbi Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations
    Robert H Dworkin
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Pain 9:105-21. 2008
    ..Provisional benchmarks for identifying clinically important changes in specific outcome measures that can be used for outcome studies of treatments for chronic pain are proposed...
  2. ncbi Acceptance of chronic pain: component analysis and a revised assessment method
    Lance M McCracken
    Pain Management Unit, Royal National Hospital for Rheumatic Diseases and University of Bath, Bath BA1 1RL, UK
    Pain 107:159-66. 2004
    ..A revised version of the CPAQ is suggested...
  3. ncbi Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment
    Harald Breivik
    University of Oslo, Faculty of Medicine, Faculty Division Rikshospitalet, Department of Anaesthesiology, Rikshospitalet University Hospital, Norway
    Eur J Pain 10:287-333. 2006
    ..Forty percent had inadequate management of their pain. Interesting differences between countries were observed, possibly reflecting differences in cultural background and local traditions in managing chronic pain...
  4. ncbi Coding of facial expressions of pain in the laboratory mouse
    Dale J Langford
    Department of Psychology and Alan Edwards Centre for Research on Pain, McGill University, Montreal, Quebec, Canada
    Nat Methods 7:447-9. 2010
    ..This measure of spontaneously emitted pain may provide insight into the subjective pain experience of mice...
  5. ncbi Quantitative assessment of tactile allodynia in the rat paw
    S R Chaplan
    Department of Anesthesiology, University of California, San Diego, La Jolla 92093 0818
    J Neurosci Methods 53:55-63. 1994
    ..Threshold measurement using the up-down paradigm, in combination with the neuropathic pain model, represents a powerful tool for analyzing the effects of manipulations of the neuropathic pain state...
  6. ncbi Neuropathic pain: redefinition and a grading system for clinical and research purposes
    R D Treede
    Institute of Physiology and Pathophysiology, Johannes Gutenberg University, Mainz, Germany
    Neurology 70:1630-5. 2008
    ..The grades probable and definite require confirmatory evidence from a neurologic examination. This grading system is proposed for clinical and research purposes...
  7. ncbi Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale
    J T Farrar
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Blockley Hall, Room 816, 423 Guardian Drive, Philadelphia, PA 19104, USA
    Pain 94:149-58. 2001
    ..Use of a standard outcome across chronic pain studies would greatly enhance the comparability, validity, and clinical applicability of these studies...
  8. ncbi Core outcome measures for chronic pain clinical trials: IMMPACT recommendations
    Robert H Dworkin
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Pain 113:9-19. 2005
  9. ncbi A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures
    Rachelle Buchbinder
    Monash Department of Clinical Epidemiology, Cabrini Hospital, and Monash University, Malvern, Vic, Australia
    N Engl J Med 361:557-68. 2009
    ..Vertebroplasty has become a common treatment for painful osteoporotic vertebral fractures, but there is limited evidence to support its use...
  10. pmc Sex, gender, and pain: a review of recent clinical and experimental findings
    Roger B Fillingim
    University of Florida, College of Dentistry, Gainesville, Florida 32610 3628, USA
    J Pain 10:447-85. 2009
    ..The article concludes with a discussion of potential biopsychosocial mechanisms that may underlie sex differences in pain, and considerations for future research are discussed...
  11. ncbi Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin
    Michael Bandell
    Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA
    Neuron 41:849-57. 2004
    ..Collectively, these data demonstrate that TRPA1 activation elicits a painful sensation and provide a potential molecular model for why noxious cold can paradoxically be perceived as burning pain...
  12. ncbi Prevalence of chronic pain with neuropathic characteristics in the general population
    Didier Bouhassira
    INSERM U 792, Centre de Traitement et d Evaluation de la Douleur, CHU Ambroise Pare, 9, avenue Charles de Gaulle, Boulogne Billancourt cedex F 92100, France
    Pain 136:380-7. 2008
    ..We identified distinctive socio-demographic profile and clinical features indicating that chronic pain with neuropathic characteristics is a specific health problem...
  13. ncbi Quantitative sensory testing: a comprehensive protocol for clinical trials
    R Rolke
    Institute of Physiology and Pathophysiology, Johannes Gutenberg University, Saarstr 21, D 55099 Mainz, Germany
    Eur J Pain 10:77-88. 2006
    ..Case examples of selected patients illustrate the value of z-transformed QST data for an easy survey of individual symptom profiles...
  14. ncbi Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4)
    Didier Bouhassira
    INSERM E 332, AP HP Hôpital Ambroise Paré, Boulogne and Université Versailles Saint Quentin, France
    Pain 114:29-36. 2005
    ..The 10-item questionnaire developed in the present study constitutes a new diagnostic instrument, which might be helpful both in clinical research and daily practice...
  15. ncbi The prevalence of pain and pain interference in a general population of older adults: cross-sectional findings from the North Staffordshire Osteoarthritis Project (NorStOP)
    Elaine Thomas
    Primary Care Sciences Research Centre, Keele University, Keele, North Staffordshire, ST5 5BG, UK
    Pain 110:361-8. 2004
    ..More importantly the extent to which pain interferes with everyday life increases incrementally with age up to the oldest age-group in the community-dwelling general population...
  16. pmc The Knee injury and Osteoarthritis Outcome Score (KOOS): from joint injury to osteoarthritis
    Ewa M Roos
    Department of Orthopaedics, Lund University Hospital, SE 221 85 Lund, Sweden
    Health Qual Life Outcomes 1:64. 2003
    ..The measure is relatively new and further use of the instrument will add knowledge and suggest areas that need to be further explored and improved...
  17. ncbi Postoperative pain experience: results from a national survey suggest postoperative pain continues to be undermanaged
    Jeffrey L Apfelbaum
    Department of Anesthesia and Critical Care, The University Chicago Hospitals, Chicago, Illinois 60637, USA
    Anesth Analg 97:534-40, table of contents. 2003
    ..Additional efforts are required to improve patients' postoperative pain experience...
  18. ncbi Animal models of nociception
    D Le Bars
    INSERM U 161, 2, rue d Alesia, 75014 Paris, France
    Pharmacol Rev 53:597-652. 2001
    ..It is concluded that although the neural basis of the most used tests is poorly understood, their use will be more profitable if pain is considered within, rather than apart from, the body's homeostatic mechanisms...
  19. ncbi Minimum clinically important difference in lumbar spine surgery patients: a choice of methods using the Oswestry Disability Index, Medical Outcomes Study questionnaire Short Form 36, and pain scales
    Anne G Copay
    The Spinal Research Foundation, 1831 Wiehle Avenue, Suite 200, Reston, VA 20190, USA
    Spine J 8:968-74. 2008
    ..Variable threshold values have been proposed as MCID for those instruments despite a lack of agreement on the optimal MCID calculation method...
  20. ncbi p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain
    Shan Xue Jin
    Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129, USA
    J Neurosci 23:4017-22. 2003
    ..Coactivation of p38 in DRG neurons and spinal microglia may contribute to later phases of neuropathic pain...
  21. ncbi Sensitization in patients with painful knee osteoarthritis
    Lars Arendt-Nielsen
    Center for Sensory Motor Interaction SMI, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark
    Pain 149:573-81. 2010
    ..This study highlights the importance of central sensitization as an important manifestation in knee OA...
  22. ncbi Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity
    R R Ji
    Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Rm 4309, Charlestown, Massachusetts 02129, USA
    Nat Neurosci 2:1114-9. 1999
    ..ERK signaling within the spinal cord is therefore involved in generating pain hypersensitivity. Because of its rapid activation, this effect probably involves regulation of neuronal excitability without changes in transcription...
  23. ncbi Pain: a review of three commonly used pain rating scales
    Amelia Williamson
    Research Nurse Pain, Birmingham Heartland s and Solihull NHS Trust, Birmingham, UK
    J Clin Nurs 14:798-804. 2005
    ..The review provides information needed to understand the main properties of the scales...
  24. ncbi NeuPSIG guidelines on neuropathic pain assessment
    Maija Haanpää
    Rehabilitation ORTON, Helsinki, Finland
    Pain 152:14-27. 2011
    ....
  25. ncbi Musculoskeletal pain in the Netherlands: prevalences, consequences and risk groups, the DMC(3)-study
    H S J Picavet
    National Institute of Public Health and the Environment, Center for Chronic Diseases Epidemiology CZE, pb 101, PO Box 1, 3720 BA, Bilthoven, The Netherlands
    Pain 102:167-78. 2003
    ..Musculoskeletal pain is common in all subgroups of the population and has far-reaching consequences for health, work and the use of health care...
  26. ncbi Animal models of pain: progress and challenges
    Jeffrey S Mogil
    Department of Psychology and Alan Edwards Centre for Research on Pain, McGill University, Montreal, Quebec, Canada
    Nat Rev Neurosci 10:283-94. 2009
    ..In addition, pain studies are importantly affected by a wide range of modulatory factors, including sex, genotype and social communication, all of which must be taken into account when using an animal model...
  27. ncbi Illness perceptions of low back pain patients in primary care: what are they, do they change and are they associated with outcome?
    Nadine E Foster
    Primary Care Musculoskeletal Research Centre, Primary Care Sciences Building, Keele University, North Staffordshire ST5 5BG, Keele, UK
    Pain 136:177-87. 2008
    ..These results have implications for the management of patients, and support the need to assess and address patients' cognitions about their back problems...
  28. ncbi Development and validation of the Neuropathic Pain Symptom Inventory
    Didier Bouhassira
    INSERM E 332, Center d Evaluation t de Traitement de la Douleur, Hôspiat Ambroise paré, Boulogne Billancourt, France
    Pain 108:248-57. 2004
    ....
  29. ncbi Placebo and opioid analgesia-- imaging a shared neuronal network
    Predrag Petrovic
    Cognitive Neurophysiology Research Group, Department of Clinical Neuroscience, Karolinska Institute, Stockholm 171 76, Sweden, Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Hospital, Finland
    Science 295:1737-40. 2002
    ..These findings indicate a related neural mechanism in placebo and opioid analgesia...
  30. ncbi Pain related behaviour in two models of osteoarthritis in the rat knee
    Janet Fernihough
    Novartis Institute for Medical Sciences, 5 Gower Place, London WCE 6BS, UK
    Pain 112:83-93. 2004
    ..Gabapentin varied in its ability to reverse both hyperalgesia and allodynia. The iodoacetate model provides a basis for studies on the mechanisms of pain in OA, and for development of novel therapeutic analgesics...
  31. ncbi Core outcome domains and measures for pediatric acute and chronic/recurrent pain clinical trials: PedIMMPACT recommendations
    Patrick J McGrath
    Dalhousie University and IWK Health Center, Halifax, Canada
    J Pain 9:771-83. 2008
    ..Specific measures or measurement strategies were recommended for different age groups for each domain...
  32. ncbi The epidemiology of chronic pain of predominantly neuropathic origin. Results from a general population survey
    Nicola Torrance
    Department of General Practice and Primary Care, University of Aberdeen, Scotland
    J Pain 7:281-9. 2006
    ..This is the first estimate of the prevalence and distribution of pain of predominantly neuropathic origin in the general population, using a previously validated and reliable data collection instrument...
  33. ncbi The impact of patient expectations on outcomes in four randomized controlled trials of acupuncture in patients with chronic pain
    Klaus Linde
    Centre for Complementary Medicine Research, Department of Internal Medicine II, Technische Universitat Munchen, Kaiserstr 9, 80801 Munich, Germany
    Pain 128:264-71. 2007
    ..03 (1.26-3.26) and 2.35 (1.68-3.30), respectively. Results from the 6-month follow-up were similar. In conclusion, in our trials a significant association was shown between better improvement and higher outcome expectations...
  34. ncbi A comparison of pain rating scales by sampling from clinical trial data
    E K Breivik
    Department of Oral Surgery and Oral Medicine, University of Oslo, Norway
    Clin J Pain 16:22-8. 2000
    ..The goals of this study were to examine agreement and estimate differences in sensitivity between pain assessment scales...
  35. ncbi Complete Freunds adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS
    Vasudeva Raghavendra
    Department of Anaesthesiology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Eur J Neurosci 20:467-73. 2004
    ..These findings further support a unifying theory that glial activation and enhanced cytokine expression at the CNS have a role in eliciting behavioral hypersensitivity...
  36. ncbi The impact of chronic pain in the community
    B H Smith
    Department of General Practice and Primary Care, University of Aberdeen, UK
    Fam Pract 18:292-9. 2001
    ..These results support the suggestion that chronic pain is multidimensional, both in its aetiology and in its effects, particularly at this end of the spectrum. This must be addressed in management and in further research...
  37. ncbi Kettlebell training for musculoskeletal and cardiovascular health: a randomized controlled trial
    Kenneth Jay
    National Research Centre for the Working Environment, Copenhagen, Denmark
    Scand J Work Environ Health 37:196-203. 2011
    ..The aim of this trial was to investigate the effectiveness of a worksite intervention using kettlebell training to improve musculoskeletal and cardiovascular health...
  38. ncbi Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia
    Claire Gaveriaux-Ruff
    IGBMC Institut de Génétique et de Biologie Moléculaire et Cellulaire, Neurobiology and Genetic Department, Illkirch F 67400, France
    Pain 152:1238-48. 2011
    ..The conditional knockout of delta-opioid receptor in primary afferent Na(V)1.8 neurons augmented mechanical allodynia in persistent pain models and abolished delta opioid analgesia in these models...
  39. ncbi Prospective validation of clinically important changes in pain severity measured on a visual analog scale
    E J Gallagher
    Department of Emergency Medicine, Albert Einstein College of Medicine, Bronx, NY 10467, USA
    Ann Emerg Med 38:633-8. 2001
    ....
  40. ncbi Comprehensive review of epidemiology, scope, and impact of spinal pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:E35-70. 2009
    ..This section of the American Society of Interventional Pain Physicians (ASIPP)/Evidence-Based Medicine (EBM) guidelines evaluates the epidemiology, scope, and impact of spinal pain and its relevance to health care interventions...
  41. pmc A randomized trial comparing acupuncture, simulated acupuncture, and usual care for chronic low back pain
    Daniel C Cherkin
    Center for Health Studies, 1730 Minor Avenue, Seattle, WA 98101, USA
    Arch Intern Med 169:858-66. 2009
    ..This trial addresses the importance of needle placement and skin penetration in eliciting acupuncture effects for patients with chronic low back pain...
  42. ncbi Systematic review of the psychometric properties, interpretability and feasibility of self-report pain intensity measures for use in clinical trials in children and adolescents
    Jennifer N Stinson
    Faculty of Nursing, University of Toronto, Hospital for Sick Children, Toronto, Ont, Canada
    Pain 125:143-57. 2006
    ..Future research is needed to strengthen the measurement of pain in clinical trials with children...
  43. ncbi The Faces Pain Scale-Revised: toward a common metric in pediatric pain measurement
    C L Hicks
    Department of Psychology, University of Saskatchewan, 9 Campus Drive, Saskatoon, SK, S7N 5A5, Canada
    Pain 93:173-83. 2001
    ..It has the advantage of being suitable for use with the most widely used metric for scoring (0-10), and conforms closely to a linear interval scale...
  44. ncbi Thermosensory activation of insular cortex
    A D Craig
    Division of Neurosurgery, Barrow Neurological Institute, 350 West Thomas Rd, Phoenix, Arizona 85013, USA
    Nat Neurosci 3:184-90. 2000
    ..Notably, perceived thermal intensity was well correlated with activation in the right (ipsilateral) anterior insular and orbitofrontal cortices...
  45. ncbi Effectiveness of acupuncture as adjunctive therapy in osteoarthritis of the knee: a randomized, controlled trial
    Brian M Berman
    University of Maryland School of Medicine, Baltimore, Maryland 21207, USA
    Ann Intern Med 141:901-10. 2004
    ..Evidence on the efficacy of acupuncture for reducing the pain and dysfunction of osteoarthritis is equivocal...
  46. ncbi Acupuncture de qi, from qualitative history to quantitative measurement
    Jian Kong
    Department of Psychiatry, Massachusetts General Hospital, Charlestown, MA 02129, USA
    J Altern Complement Med 13:1059-70. 2007
    ....
  47. pmc Evaluation of clinically relevant changes in patient reported outcomes in knee and hip osteoarthritis: the minimal clinically important improvement
    F Tubach
    Institut National de la Sante et de la Recherche Medicale, Département d Epidémiologie, Biostatistique et Recherche Clinique, 75018 Paris, France
    Ann Rheum Dis 64:29-33. 2005
    ..In clinical trials, at the group level, results are usually reported as mean and standard deviation of the change in score, which is not meaningful for most readers...
  48. ncbi Effective treatment of chronic low back pain in humans reverses abnormal brain anatomy and function
    David A Seminowicz
    Alan Edwards Centre for Research on Pain, McGill Scoliosis and Spine Research Group, McGill University, Montreal, Quebec H3A 1A4, Canada
    J Neurosci 31:7540-50. 2011
    ..These data indicate that functional and structural brain abnormalities-specifically in the left DLPFC-are reversible, suggesting that treating chronic pain can restore normal brain function in humans...
  49. ncbi Depression in rheumatoid arthritis: a systematic review of the literature with meta-analysis
    Chris Dickens
    Department of Psychiatry, Manchester University, Manchester, UK
    Psychosom Med 64:52-60. 2002
    ..In addition, we investigated the extent to which sociodemographic characteristics, level of pain, and method of assessing depression might affect the degree of depression...
  50. pmc Mechanisms of neuropathic pain
    James N Campbell
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Neuron 52:77-92. 2006
    ..The rapid gain in knowledge about abnormal signaling promises breakthroughs in the treatment of these often debilitating disorders...
  51. ncbi Patient compliance with paper and electronic diaries
    Arthur A Stone
    Department of Psychiatry and Behavioral Science, Stony Brook University, NY 11794, USA
    Control Clin Trials 24:182-99. 2003
    ..The findings call into question the use of paper diaries and suggest that electronic diaries with compliance-enhancing features are a more effective way of collecting diary information...
  52. ncbi Heritability of nociception I: responses of 11 inbred mouse strains on 12 measures of nociception
    J S Mogil
    Department of Psychology, University of Illinois at Urbana Champaign, Champaign 61820, USA
    Pain 80:67-82. 1999
    ..30-0.76) and mediation by a limited number of apparent genetic loci. Data comparing inbred strains have considerable utility as a tool for understanding the genetics of nociception, and a particular relevance to transgenic studies...
  53. ncbi Responsiveness of the numeric pain rating scale in patients with low back pain
    John D Childs
    Department of Physical Therapy, Wilford Hall Medical Center, San Antonio, TX, USA
    Spine (Phila Pa 1976) 30:1331-4. 2005
    ..Cohort study of patients with low back pain (LBP) receiving physical therapy...
  54. ncbi Mirror therapy for phantom limb pain
    Brenda L Chan
    N Engl J Med 357:2206-7. 2007
  55. ncbi Tanezumab for the treatment of pain from osteoarthritis of the knee
    Nancy E Lane
    Department of Medicine, University of California at Davis Medical School, Sacramento, CA 95817, USA
    N Engl J Med 363:1521-31. 2010
    ..This proof-of-concept study was designed to investigate the safety and analgesic efficacy of tanezumab, a humanized monoclonal antibody that binds and inhibits nerve growth factor...
  56. pmc Dynamic load at baseline can predict radiographic disease progression in medial compartment knee osteoarthritis
    T Miyazaki
    Department of Orthopaedic Surgery, Fukui Medical University, Japan
    Ann Rheum Dis 61:617-22. 2002
    ..To test the hypothesis that dynamic load at baseline can predict radiographic disease progression in patients with medial compartment knee osteoarthritis (OA)...
  57. ncbi Quantitative prediction of subjective pain intensity from whole-brain fMRI data using Gaussian processes
    Andre Marquand
    Department of Clinical Neuroscience, Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, UK
    Neuroimage 49:2178-89. 2010
    ..For classification, GP models perform categorical prediction as accurately as a support vector machine classifier and furnish probabilistic class predictions...
  58. ncbi How important are back pain beliefs and expectations for satisfactory recovery from back pain?
    Chris J Main
    Arthritis Research Campaign National Primary Care Centre, Keele University, N Staffs, UK, ST5 5BG, United Kingdom
    Best Pract Res Clin Rheumatol 24:205-17. 2010
    ..The article concludes with a summary of the key messages for clinical management of patients presenting with painful conditions and suggestions for further research...
  59. ncbi Characterizing the course of low back pain: a latent class analysis
    Kate M Dunn
    Primary Care Sciences Research Centre, Keele University, Keele, United Kingdom
    Am J Epidemiol 163:754-61. 2006
    ..Identification of four distinct groups of patients improves understanding of the course of back pain and may provide a basis of classification for intervention...
  60. ncbi The clinical importance of changes in outcome scores after treatment for chronic low back pain
    O Hägg
    Department of Orthopaedic Surgery, Sahlgren University Hospital, 413 45 Gothenburg, Sweden
    Eur Spine J 12:12-20. 2003
    ..Despite improvement after treatment, the ability to sit, stand and lift, remain notable problems...
  61. ncbi A randomized controlled trial comparing 2 types of spinal manipulation and minimal conservative medical care for adults 55 years and older with subacute or chronic low back pain
    Maria A Hondras
    Palmer Center for Chiropractic Research, Davenport, Iowa 52803, USA
    J Manipulative Physiol Ther 32:330-43. 2009
    ..The purpose of this study was to compare the effects of 2 biomechanically distinct forms of SM and minimal conservative medical care (MCMC) for participants at least 55 years old with subacute or chronic nonradicular LBP...
  62. ncbi Neuropathic pain: are there distinct subtypes depending on the aetiology or anatomical lesion?
    N Attal
    INSERM U 792, Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, APHP, Boulogne Billancourt, F 92100, France
    Pain 138:343-53. 2008
    ....
  63. ncbi The spectrum of neuropathy in diabetes and impaired glucose tolerance
    C J Sumner
    Department of Neurology, The Johns Hopkins University, Baltimore, MD, USA
    Neurology 60:108-11. 2003
    ..To compare the neuropathy associated with impaired glucose tolerance (IGT) and diabetes mellitus (DM) determined by oral glucose tolerance testing (OGTT)...
  64. ncbi Midbrain control of spinal nociception discriminates between responses evoked by myelinated and unmyelinated heat nociceptors in the rat
    Simon McMullan
    Hypertension and Stroke Research Laboratory, University of Sydney, Sydney, Australia
    Pain 124:59-68. 2006
    ....
  65. pmc The impact of gender, age, and preoperative pain severity on pain after TKA
    Jasvinder A Singh
    Department of Health Sciences Research, Mayo Clinic School of Medicine, Rochester, MN, USA
    Clin Orthop Relat Res 466:2717-23. 2008
    ..We conclude female gender, younger age, and worse preoperative pain predict greater risk of moderate-severe pain postoperatively in patients with primary and revision TKA...
  66. ncbi Psychophysical outcomes from a randomized pilot study of manual, electro, and sham acupuncture treatment on experimentally induced thermal pain
    Jian Kong
    Department of Psychiatry, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    J Pain 6:55-64. 2005
    ..This suggests that attributes of the deqi sensation may be useful clinical indicators of effective treatment...
  67. ncbi Validation of the Brief Pain Inventory for chronic nonmalignant pain
    Gabriel Tan
    Pain Section, Anesthesiology and Mental Health Care Line Substance Dependence Treatment Program, Houston VA Medical Center, and Department of Anesthesiology, Baylor College of Medicine, TX 77030, USA
    J Pain 5:133-7. 2004
    ..Finally, the finding that both BPI scales showed statistically significant improvement with treatment confirms the responsivity of BPI in detecting and reflecting improvement in pain over time...
  68. pmc Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain
    Anna K Clark
    Novartis Institutes for BioMedical Research, London WC1E 6BS, United Kingdom
    Proc Natl Acad Sci U S A 104:10655-60. 2007
    ....
  69. ncbi Effect of physical exercise interventions on musculoskeletal pain in all body regions among office workers: a one-year randomized controlled trial
    Lars L Andersen
    National Research Centre for the Working Environment, Lersø Parkallé 105, DK 2100 Copenhagen Ø, Denmark
    Man Ther 15:100-4. 2010
    ..In conclusion, both specific resistance training and all-round physical exercise for office workers caused better effects than a reference intervention in relieving musculoskeletal pain symptoms in exposed regions of the upper body...
  70. ncbi Treatment of chronic elbow tendinosis with buffered platelet-rich plasma
    Allan Mishra
    Department of Orthopedic Surgery, Menlo Medical Clinic, Stanford University Medical Center, 1300 Crane Street, Menlo Park, CA 94025, USA
    Am J Sports Med 34:1774-8. 2006
    ..Elbow epicondylar tendinosis is a common problem that usually resolves with nonoperative treatments. When these measures fail, however, patients are interested in an alternative to surgical intervention...
  71. ncbi Deqi sensation between the acupuncture-experienced and the naïve: a Korean study II
    Jongbae Park
    Complementary Medicine, Peninsula Medical School, Universities of Exeter and Plymouth, UK
    Am J Chin Med 33:329-37. 2005
    ..In addition, a constellation of Deqi-related acupuncture-specific sensations is more than just a general pain intensity dimension, which requires a biochemical and physiological exploration...
  72. pmc Enhanced central pain processing of fibromyalgia patients is maintained by muscle afferent input: a randomized, double-blind, placebo-controlled study
    Roland Staud
    Department of Medicine, University of Florida, Gainesville, FL 32610, USA
    Pain 145:96-104. 2009
    ..02). Neither lidocaine nor saline injections significantly affected clinical FM pain ratings, a result most likely due to the very low dose of lidocaine (50mg) used in this trial...
  73. ncbi Somatotopic organisation of the human insula to painful heat studied with high resolution functional imaging
    J C W Brooks
    Department of Human Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK
    Neuroimage 27:201-9. 2005
    ..037). Based on single subject analyses, the average standard space (MNI) coordinates for face, hand and foot activity were (-40,-16,11), (-40,-19,14) and (-35,-21,11) respectively...
  74. ncbi Vertebroplasty versus conservative treatment in acute osteoporotic vertebral compression fractures (Vertos II): an open-label randomised trial
    Caroline A H Klazen
    Radiology, St Elisabeth Ziekenhuis, Tilburg, Netherlands
    Lancet 376:1085-92. 2010
    ..We aimed to clarify whether vertebroplasty has additional value compared with optimum pain treatment in patients with acute vertebral fractures...
  75. pmc The c-Jun N-terminal kinase 1 (JNK1) in spinal astrocytes is required for the maintenance of bilateral mechanical allodynia under a persistent inflammatory pain condition
    Yong Jing Gao
    Sensory Plasticity Laboratory, Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Pain 148:309-19. 2010
    ..Our findings also reveal a unique role of JNK1 and astrocyte network in regulating tactile allodynia and contralateral pain...
  76. pmc Spinal protein kinase M ζ underlies the maintenance mechanism of persistent nociceptive sensitization
    Marina N Asiedu
    Department of Pharmacology, The University of Arizona College of Medicine, Tucson, AZ 85721, USA
    J Neurosci 31:6646-53. 2011
    ....
  77. ncbi Recognition of central sensitization in patients with musculoskeletal pain: Application of pain neurophysiology in manual therapy practice
    Jo Nijs
    Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Belgium
    Man Ther 15:135-41. 2010
    ..The clinical examination used to recognize central sensitization entails the distinction between primary and secondary hyperalgesia...
  78. pmc Oral sucrose as an analgesic drug for procedural pain in newborn infants: a randomised controlled trial
    Rebeccah Slater
    Nuffield Department of Anaesthetics, University of Oxford, Oxford, UK
    Lancet 376:1225-32. 2010
    ..We assessed whether sucrose administration reduces pain-specific brain and spinal cord activity after an acute noxious procedure in newborn infants...
  79. pmc A modified Delphi approach to standardize low back pain recurrence terminology
    Tasha R Stanton
    The George Institute for Global Health, The University of Sydney, PO Box M201, Missenden Road, Sydney, NSW, 2050, Australia
    Eur Spine J 20:744-52. 2011
    ..Future research is necessary to evaluate these definitions...
  80. ncbi Acute pain in herpes zoster and its impact on health-related quality of life
    Jennifer Katz
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, 14642, USA
    Clin Infect Dis 39:342-8. 2004
    ..The increasing incidence of herpes zoster that can be anticipated as the population ages requires that clinical trials that examine interventions to prevent or treat herpes zoster pain be given a high priority...
  81. ncbi Increase in muscle nociceptive substances and anaerobic metabolism in patients with trapezius myalgia: microdialysis in rest and during exercise
    Lars Rosendal
    National Institute of Occupational Health, Lersø Parkallé 105, DK 2100 Copenhagen, Denmark
    Pain 112:324-34. 2004
    ..In addition, TM was associated with increased anaerobic metabolism, whereas a normal rise in blood flow was seen with exercise. These findings indicate that peripheral nociceptive processes are active in work-related TM...
  82. ncbi Evidence of augmented central pain processing in idiopathic chronic low back pain
    Thorsten Giesecke
    University of Michigan, Ann Arbor, MI 48106, USA
    Arthritis Rheum 50:613-23. 2004
    ..We compared the results of both of these methods as applied to patients with idiopathic CLBP (n = 11), patients with widespread pain (fibromyalgia; n = 16), and healthy control subjects (n = 11)...
  83. ncbi Imaging how attention modulates pain in humans using functional MRI
    Susanna J Bantick
    Oxford University Department of Clinical Neurology, Centre for Functional Magnetic Resonance Imaging of the Brain, John Radcliffe Hospital, Headington, Oxford, UK
    Brain 125:310-9. 2002
    ..In contrast, many areas of the pain matrix (i.e. thalamus, insula, cognitive division of the ACC) displayed reduced activation, supporting the behavioural results of reduced pain perception...
  84. pmc Opioids for chronic noncancer pain: a meta-analysis of effectiveness and side effects
    Andrea D Furlan
    Comprehensive Pain Program, Toronto Western Hospital, Ont
    CMAJ 174:1589-94. 2006
    ..Chronic noncancer pain (CNCP) is a major health problem, for which opioids provide one treatment option. However, evidence is needed about side effects, efficacy, and risk of misuse or addiction...
  85. ncbi The outcome and repair integrity of completely arthroscopically repaired large and massive rotator cuff tears
    Leesa M Galatz
    Shoulder and Elbow Service, Department of Orthopaedic Surgery, Washington University School of Medicine at Barnes Jewish Hospital, One Barnes Jewish Hospital Plaza, Suite 11300, West Pavilion, St Louis, MO 63110, USA
    J Bone Joint Surg Am 86:219-24. 2004
    ....
  86. ncbi Interpreting change scores for pain and functional status in low back pain: towards international consensus regarding minimal important change
    Raymond W J G Ostelo
    EMGO Institute, VU University Medical Centre, Amsterdam, The Netherlands
    Spine (Phila Pa 1976) 33:90-4. 2008
    ..Literature review, expert panel, and a workshop during the "VIII International Forum on Primary Care Research on Low Back Pain" (Amsterdam, June 2006)...
  87. ncbi Endplate potentials are common to midfiber myofacial trigger points
    David G Simons
    Department of Physical Medicine and Rehabilitation, University of California Irvine, USA
    Am J Phys Med Rehabil 81:212-22. 2002
    ....
  88. ncbi Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial
    M Backonja
    Department of Neurology, University of Wisconsin, Madison 53792, USA
    JAMA 280:1831-6. 1998
    ..Pain is the most disturbing symptom of diabetic peripheral neuropathy. As many as 45% of patients with diabetes mellitus develop peripheral neuropathies...
  89. ncbi Estimating utility values for health states of type 2 diabetic patients using the EQ-5D (UKPDS 62)
    Philip Clarke
    Med Decis Making 22:340-9. 2002
    ..The aim of this study was to analyze quality-of-life data from the United Kingdom Prospective Diabetes Study (UKPDS) to estimate the impact of diabetes-related complications on utility-based measures of quality of life...
  90. ncbi Pain among children and adolescents: restrictions in daily living and triggering factors
    Angela Roth-Isigkeit
    Department of Anesthesiology, University of Schleswig Holstein, Campus Luebeck, Ratzeburger Allee 160, D 23538 Luebeck, Germany
    Pediatrics 115:e152-62. 2005
    ....
  91. ncbi A comparison of a modified Oswestry Low Back Pain Disability Questionnaire and the Quebec Back Pain Disability Scale
    J M Fritz
    Department of Physical Therapy, School of Allied Health and Rehabilitation Sciences, University of Pittsburgh, 6035 Forbes Tower, Pittsburgh, PA 15260, USA
    Phys Ther 81:776-88. 2001
    ....
  92. ncbi The importance of patient expectations in predicting functional outcomes after total joint arthroplasty
    Nizar N Mahomed
    Division of Orthopaedic Surgery, Toronto Western Hospital, University of Toronto, ON, Canada
    J Rheumatol 29:1273-9. 2002
    ..Multivariate regression models were used to evaluate the impact of expectations on outcomes...
  93. ncbi Mechanisms of disease: neuropathic pain--a clinical perspective
    Ralf Baron
    Department of Neurological Pain Research and Therapy, Christian Albrechts Universitat Kiel, Germany
    Nat Clin Pract Neurol 2:95-106. 2006
    ..This review discusses the conceptual framework of the novel mechanism-based classification, encouraging the reader to see neuropathic pain as a clinical entity rather than a compilation of single disease states...
  94. ncbi Assessment of pain
    H Breivik
    Faculty of Medicine, University of Oslo, Oslo, Norway
    Br J Anaesth 101:17-24. 2008
    ..Several disease- and patient-specific functional scales are useful, such as the Western Ontario and MacMaster Universities for osteoarthritis, and several neuropathic pain screening tools. The Initiative on..
  95. ncbi Intrathecal minocycline attenuates peripheral inflammation-induced hyperalgesia by inhibiting p38 MAPK in spinal microglia
    Xiao Ying Hua
    Department of Anaesthesiology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0818, USA
    Eur J Neurosci 22:2431-40. 2005
    ....
  96. ncbi The Pain Catastrophizing Scale: further psychometric evaluation with adult samples
    A Osman
    Department of Psychology, University of Northern Iowa, Cedar Falls 50614 0505, USA
    J Behav Med 23:351-65. 2000
    ..Overall, the results showed strong evidence of criterion-related, concurrent, and discriminant validity for the PCS in the community sample. Limitations of the present study are discussed...
  97. ncbi EFNS guidelines on neuropathic pain assessment
    G Cruccu
    EFNS Panel on Neuropathic Pain Department of Neurological Sciences, La Sapienza University, Rome, Italy
    Eur J Neurol 11:153-62. 2004
    ..A laboratory measure of pain that by-passes the subjective report, and thus cognitive influences, is a hopeful aim for the future...
  98. ncbi The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats
    Vasudeva Raghavendra
    Department of Anesthesiology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    J Neurosci 22:9980-9. 2002
    ..Targeting central cytokine production and glial activation may improve the effectiveness of morphine and reduce the incidence of morphine withdrawal-induced hyperalgesia and allodynia in neuropathic pain conditions...
  99. ncbi Acupuncture and knee osteoarthritis: a three-armed randomized trial
    Hanns Peter Scharf
    University of Heidelberg, Heidelberg, Germany
    Ann Intern Med 145:12-20. 2006
    ..Despite the popularity of acupuncture, evidence of its efficacy for reducing pain remains equivocal...
  100. pmc The minimum clinically significant difference in visual analogue scale pain score does not differ with severity of pain
    A M Kelly
    Department of Emergency Medicine, Western Hospital, Melbourne, Australia
    Emerg Med J 18:205-7. 2001
    ..To determine whether minimum clinically significant difference in visual analogue scale (VAS) pain score varies according to the severity of pain reported...
  101. pmc A randomized trial of vertebroplasty for osteoporotic spinal fractures
    David F Kallmes
    Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    N Engl J Med 361:569-79. 2009
    ..Vertebroplasty is commonly used to treat painful, osteoporotic vertebral compression fractures...

Research Grants71

  1. Facial Expression During Pain
    MAMOONA ARIF; Fiscal Year: 2009
    ..This study will evaluate the type of facial expressions seen in these patients to improve nursing assessment and management of pain. ..
  2. Online patient self-assessment for chronic pancreatic and other pain
    Andrew H Soll; Fiscal Year: 2011
    ..Although we focus on chronic pancreatic pain, we are using a general approach that will be applicable to any chronic pain or non-pain symptom. ..
  3. Vestibular rehabilitation and dizziness in geriatric patients
    Courtney Hall; Fiscal Year: 2012
    ..This project will contribute to improved quality of life and containment of health care costs in the elderly. ..
  4. Testing the feasibility of patient-controlled sedation in ventilated ICU patients
    Craig R Weinert; Fiscal Year: 2013
    ..Demonstrating the safety and feasibility of patient-controlled sedation in this patient population has the potential to positively impact outcomes for thousands of mechanically ventilated ICU patients each year in the U.S. ..
  5. Acupressure for Persistent Cancer Related Fatigue
    Suzanna M Zick; Fiscal Year: 2013
    ....
  6. CaMKII as a Mechanism &Intervention Target for Sickle Cell Pain
    Zaijie Jim Wang; Fiscal Year: 2013
    ..Unfortunately, the investigators did not report other pain measurement findings or define a pain phenotype in Berkeley sickle transgenic mice, a model of a more severe form of SCD...
  7. Pain Assessment & Intervention Needs (PAIN)
    Fern Fitzhenry; Fiscal Year: 2010
    ..We will also data mine for other implicit, previously unknown, useful information such as conditions that should trigger or escalate an alert for an acute pain management intervention. ..
  8. Comparing focused ultrasound and uterine artery embolization for uterine fibroids
    Elizabeth A Stewart; Fiscal Year: 2010
    ..with their menstrual periods and at other times in the month and whether pain is decreased by uterine artery embolization (UAE) and magnetic resonance guided focused ultrasound (MRgFUS), two minimally-invasive treatments for fibroids ..
  9. Novel Pelvic Floor Pain Measures to Enhance Female Pelvic Pain Evaluation
    FRANK FU SHENG TU; Fiscal Year: 2012
    ....
  10. Developing an Automated Symptom Monitoring Device for Adolescents with Asthma
    Hyekyun Rhee; Fiscal Year: 2012
    ....
  11. Traditional Chinese Medicine for Fibromyalgia: A Whole Systems Trial
    Scott David Mist; Fiscal Year: 2013
    ..It will also confirm previous research on nociceptive dorsal reflex threshold biomarkers in fibromyalgia populations providing greater confidence in it use. ..
  12. Adolescents at risk for chronic pain
    ANNA CAMILLE WILSON; Fiscal Year: 2013
    ..The long-term goal is to prevent the development of adult chronic pain and related disability. ..
  13. HCV and Pain in Substance Users With and Without HIV
    Judith Tsui; Fiscal Year: 2013
    ..The comprehensive training plan includes formal coursework, as well as "hands-on" training in pain measurement and experimental pain models. Dr. Tsui's primary mentor will be Dr...
  14. Cannabidiol Modulation of ???-9-THC???s Psychotomimetic Effects in Healthy Humans
    Mohini Ranganathan; Fiscal Year: 2012
    ..CBD targets the cannabinoid system and may have antipsychotic properties. Thus, exploration of its antipsychotic properties may lead to newer therapeutic options for schizophrenia. ..
  15. Characterization of the Response to the Kappa Opiate Agonist Salvinorin A in Heal
    Mohini Ranganathan; Fiscal Year: 2012
    ....
  16. Validation of the Children's International Mucositis Evaluation Scale (ChIMES)
    Lillian Sung; Fiscal Year: 2011
    ....
  17. Neuroimaging-based biomarkers for two components of pain
    Edward E Smith; Fiscal Year: 2010
    ....
  18. Psychological Screening Instruments for Older Adults in Medical Settings
    TAMARA J KUHN; Fiscal Year: 2012
    ..While these screening tools have been shown to be effective, many have not been well used or integrated into primary care settings. ..
  19. Ethical Issues in Broad Data Sharing for Addiction Research: Best Research Practi
    MARILYN ELIZABETH COORS; Fiscal Year: 2012
    ....
  20. Non-cancer pain and cognitive impairment: A disabling relationship
    Joseph W Shega; Fiscal Year: 2012
    ..Shega regularly throughout the award period. His advisory panel includes: (1) D. Weiner-non- cancer pain measurement and functional outcomes, (2) M. Ersek-educational interventions in non-cancer pain, (3) K...
  21. Simplifying the diagnostic process of TMJD pain for the general dentist
    Mike T John; Fiscal Year: 2013
    ....
  22. Tablet-based Skills Development of Pain Management Skills
    KAREN ROSSIE; Fiscal Year: 2012
    ..Future health professionals who are more proficient in core competencies related to pain management will be better equipped to reduce the suffering and costs of inadequate pain treatment. ..
  23. Tinnitus Retraining Therapy Trial
    Roberta W Scherer; Fiscal Year: 2013
    ....
  24. Interactive Program to Manage and Prevent Back Pain
    A Blair Irvine; Fiscal Year: 2013
    ..In Phase II, the complete program will be developed and evaluated in a randomized controlled trial with 300 workers diagnosed with NLBP. The evaluation will be conducted entirely online, across the United States. ..
  25. Development of a new technology for assessing pediatric pain (NTAP)
    Jeannie S Huang; Fiscal Year: 2013
    ....
  26. Acute Decompensated Heart Failure: Treatment Timing and Effects on Outcomes
    CHAD ERIC DARLING; Fiscal Year: 2013
    ..This approach will allow me to address my aims in multiple ED settings including teaching and community hospitals. ..
  27. A Phase 3, Double-Blind Efficacy, Safety and Dose-Response Study of Lofexidine (S
    Charles W Gorodetzky; Fiscal Year: 2013
    ..NIDA's support of this development work on lofexidine is necessary to enable FDA approval of the first non-narcotic, non-addictive treatment for opioid withdrawal. ..
  28. Resistance Exercise Effects on Fear Avoidance Beliefs and Physical Function in Ob
    Heather K Vincent; Fiscal Year: 2012
    ....
  29. Deep brain stimulation of the ventral anterior limb of the internal capsule for m
    Andre Machado; Fiscal Year: 2009
    ..In this proposal, we describe an innovative approach to alleviate suffering and disability among those with severe and refractory chronic neuropathic pain. ..
  30. Jackson Hall Animal Physiology, Behavioral Phenotyping and Imaging Research Core
    Mark S Paller; Fiscal Year: 2010
    ..The proposed redesign and renovation will create modern core research laboratories with the capacity to serve large numbers of basic and translational biomedical investigators at the University of Minnesota. ..
  31. Effectiveness and Feasibility of Patient Controlled Analgesia in the ED
    ADRIENNE JEANNE BIRNBAUM; Fiscal Year: 2013
    ..Patient-controlled analgesia has great potential to address this problem if effectiveness and feasibility of application to the ED setting are demonstrated in this study. ..
  32. TMJ Intra-Articular Disorders: Impact on Pain, Functioning and Disability
    Eric L Schiffman; Fiscal Year: 2013
    ..This project will provide knowledge necessary for development of evidence-based guidelines for TMJD diagnosis and management, as well as contribute to cost effective imaging and elimination of unnecessary diagnostic radiation. ..
  33. Ethnic Differences in Acute Pain and Analgesic Response
    Barbara A Hastie; Fiscal Year: 2010
    ....
  34. Low-Cost Tool for Diagnosis and Treatment-Tracking of Low Back Pain Patients
    JOHN PAUL CONDON; Fiscal Year: 2012
    ..In this way, our research seeks to impact the clinical care of patients by developing a new integrated multi-level paradigm with high sensitivity for distinguishing patient specific motion patterns and the outcomes of their treatment. ..
  35. Managing Acute Pain in Critically Ill Non-communicative Palliative Care Patients
    Carl B Shanholtz; Fiscal Year: 2013
    ....
  36. Pain Assessment Interview and Clinical Advisory System
    Stephen F Butler; Fiscal Year: 2012
    ..We believe this product has enormous commercial viability and public health importance and that its innovative combination of features will overcome obstacles to adoption that have plagued other electronic pain assessment systems. ..
  37. Optimal assessment of HAART adherence in routine clinical care
    Heidi M Crane; Fiscal Year: 2012
    ..Optimally and routinely assessing adherence in clinical settings is an important step toward maximizing the potential benefit of antiretroviral therapy for all patients. ..
  38. fMRI-based Biomarkers for Multiple Components of Pain
    TOR DESSART WAGER; Fiscal Year: 2013
    ..These data will allow us to develop and validate new, more comprehensive biomarkers that can assess multiple aspects of pain across healthy individuals and chronic pain sufferers. ..
  39. Pain and Musculoskeletal Disorders: Translating Scientific Advances into Practice
    Daniel J Clauw; Fiscal Year: 2010
    ..abstract_text> ..
  40. Tinnitus Retraining Therapy Trial (TRTT)
    CHARLES CRAIG FORMBY; Fiscal Year: 2013
    ..Study centers will include a Study Chair[unreadable]s Office, Data Coordination Center, and 6 Clinical Centers, which offer a rich and diverse population for the study of primary tinnitus in the TRTT. ..
  41. Online Psychosocial Assessment Instruments Technology Transfer
    EDWIN JOSEPH SELKER; Fiscal Year: 2010
    ....
  42. Empowering SCD Patients with Web Tools to Improve Care Communications
    Allen Y Tien; Fiscal Year: 2012
    ..The evaluation of the product will address the potential burden of use for both patient and ED staff, and assess benefits in comparison to current practices. ..
  43. Enhancing PROMIS in Pediatric Pain, Rheumatology, and Rehabilitation Research
    ESI M MORGAN DEWITT; Fiscal Year: 2013
    ..The expected outcome of the project is to foster use of PROMIS for improved PRO measurement in Pediatric Pain, Rheumatology and Rehabilitation Research. ..
  44. Alleviating Opioid-Induced Hyperalgesia with Novel Pharmacotherapy
    Jianren Mao; Fiscal Year: 2013
    ..abstract_text> ..
  45. Social and behavioral influences on clinical communication and pain management
    CLEVELAND GEORGE SHIELDS; Fiscal Year: 2013
    ..Results from this research will inform interventions for physicians and patients to promote better communication and thereby reduce or eliminate racial disparities in care. ..
  46. Behavioral Assays for Orofacial Pain
    Charles G Widmer; Fiscal Year: 2012
    ....
  47. The Role of Ghrelin in Cancer Cachexia
    Jose M Garcia; Fiscal Year: 2013
    ....
  48. iPadEMR Pain Management Simulator: Tablet-based Skills Development
    BRADLEY TANNER; Fiscal Year: 2013
    ..A.s, physical therapists and others. Our solution will support ongoing assessment of the training to determine areas of weakness which can be refined and improved over time. ..
  49. Chronic Pain and Opioid Dependence Assessment and Treatment
    Declan T Barry; Fiscal Year: 2012
    ....
  50. TMS in the Management of Postoperative Pain
    Jeffrey J Borckardt; Fiscal Year: 2010
    ..Thus, new interventions that have the potential to reduce reliance on postoperative morphine in this patient population such as TMS need to be explored. ..
  51. Chronic Pain in Pediatric Primary Care
    AMY S LEWANDOWSKI HOLLEY; Fiscal Year: 2013
    ..These studies will lay the groundwork for future investigations examining profiles or clinical phenotypes of children in primary care who are at-risk for chronic pain;data that can inform a predictive model of chronic pain development. ..
  52. Medial Collapse Movement Impairments associated with Patellofemoral Pain
    GRETCHEN SALSICH; Fiscal Year: 2009
    ..Ultimately, the number of individuals with PFP, and the disability and cost associated with this condition would be reduced. ..
  53. ELDER PAIN--ASSESSMENT OF INTENSITY
    Keela Herr; Fiscal Year: 1999
    ..It is essential that methodological studies which determine instruments' abilities to measure pain in the elderly precede substantive investigations to manage pain in this population. ..
  54. Biomechanical Effects of Industrial Eccentric Exertions
    Robert Radwin; Fiscal Year: 2004
    ..abstract_text> ..
  55. CHRONIC LOW BACK PAIN AS A MODEL OF FIBROMYALGIA
    Daniel Clauw; Fiscal Year: 2002
    ..abstract_text> ..
  56. Iowa Pelvic Floor Disorders Clinical Trials Network
    Karl Kreder; Fiscal Year: 2005
    ..abstract_text> ..
  57. Dental Anxiety, Pain & Melanocortin-1 Receptor Mutations
    Edwin Liem; Fiscal Year: 2005
    ....
  58. DRUG-INDUCED SHIVERING--EFFECTS OF A NURSING MEASURE
    BARBARA HOLTZCLAW; Fiscal Year: 1990
    ..If effective, the intervention provides a low cost, easily administered alternative to drugs for shivering suppression and the basis for developing interventions for shivering in other clinical situations...
  59. The 7th International Conference on Pain & Chemical Dependency
    Russell Portenoy; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  60. PAIN MEASUREMENT IN BONE MARROW TRANSPLANTATION
    Mark Schubert; Fiscal Year: 2000
    ..severity and pain, and demonstrate a relationship between them, they have a unique opportunity to develop new pain measurement methodology...
  61. DCC--INTERSTITIAL CYSTITIS CLINICAL TRIALS GROUP
    J Landis; Fiscal Year: 2003
    ..The DCC will provide expertise in the design and conduct of clinical trials, pain measurement, selection of outcome measures, and identification of prognostically different subgroups of patients...
  62. DYSPNEA, AIRWAY RESISTANCE AND PRESSURE WITH SUCTIONING
    Carol Thompson; Fiscal Year: 1993
    ..Addressing these questions could prolong life and reduce hospital costs by providing a basis for nursing care decisions regarding suctioning, since dyspnea is associated with mortality and delayed weaning from the ventilators. ..
  63. Aerobic Exercise Intervention for Knee Osteoarthritis
    Kenton Kaufman; Fiscal Year: 2005
    ..Hypothesis: A effective exercise prescription for adults with degenerative joint disease is dependent on knee compartment involvement, CIA stage, BMI, and type of exercise prescribed. ..
  64. Taut Bands in Myofascial Pain
    Kai Nan An; Fiscal Year: 2011
    ..Magnetic Resonance Elastography is able to image and measure muscle stiffness and therefore is a promising technique to accurately detect changes in stiff taut bands and trigger points after manual therapy treatment. ..
  65. Functional assessment in the management of sickle cell pain in children
    WILLIAM TODD ZEMPSKY; Fiscal Year: 2012
    ..This project will develop a functional assessment tool for the measurement of pain in sickle cell disease. We hope this will result in a marked improvement in the care of these children. ..
  66. EDUCATING NURSES: MANAGING CANCER PAIN IN RURAL PATIENTS
    JO DALTON; Fiscal Year: 1993
    ....
  67. Pain Assessment in Elders with Osteoarthritis
    Pao Feng Tsai; Fiscal Year: 2004
    ..The Verbal Descriptor Scale will measure self-report of pain. Logistic regression will be used to achieve the specific aim. ..
  68. QUALITY OF LIFE AND TREATMENT FOR BRAIN TRAUMA
    Jason Doctor; Fiscal Year: 2003
    ....
  69. BEHAVIORAL CONTROL OF PAIN WITH CANCER TREATMENT
    William Redd; Fiscal Year: 1980
    ..A multiple baseline design will be used with each subject serving her own control. Computer-based, spectral analyses (using an interrupted time series design) will be conducted to evaluate the effect of the treatment procedures. ..
  70. FOREBRAIN MECHANISMS IN CHRONIC NON-NEUROPATHIC PAIN
    Kenneth Casey; Fiscal Year: 2002
    ....
  71. Sociodemographics and HRQL: Mapping the SF-12 and EQ-5D
    Erica Lubetkin; Fiscal Year: 2003
    ..In addition, understanding the relationship between the two measures could allow data from studies initially undertaken for one purpose (i.e. clinical trials, quality assessment) to be used for the other (i.e. CEA). ..