neurologic examination

Summary

Top Publications

  1. ncbi Factor structure of the Neurological Evaluation Scale in a predominantly African American sample of patients with schizophrenia, unaffected relatives, and non-psychiatric controls
    Michael T Compton
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 49 Jesse Hill Jr Drive, S E, Atlanta, GA 30303, USA
    Schizophr Res 84:365-77. 2006
  2. ncbi Distal symmetric polyneuropathy: a definition for clinical research: report of the American Academy of Neurology, the American Association of Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation
    J D England
    Neurology 64:199-207. 2005
  3. ncbi Neurodevelopmental and functional outcomes of extremely low birth weight infants in the National Institute of Child Health and Human Development Neonatal Research Network, 1993-1994
    B R Vohr
    Women and Infants Hospital, Providence, Rhode Island 02905, USA
    Pediatrics 105:1216-26. 2000
  4. pmc The modified bradykinesia rating scale for Parkinson's disease: reliability and comparison with kinematic measures
    Dustin A Heldman
    Division of Movement Disorders, Cleveland Medical Devices, Inc, Cleveland, Ohio, USA
    Mov Disord 26:1859-63. 2011
  5. doi Neonatal brain structure on MRI and diffusion tensor imaging, sex, and neurodevelopment in very-low-birthweight preterm children
    Jessica Rose
    Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA, USA
    Dev Med Child Neurol 51:526-35. 2009
  6. ncbi Does the National Institutes of Health Stroke Scale favor left hemisphere strokes? NINDS t-PA Stroke Study Group
    D Woo
    Department of Neurology, University of Cincinnati, Cincinnati, Ohio 45220, USA
    Stroke 30:2355-9. 1999
  7. ncbi Möbius syndrome redefined: a syndrome of rhombencephalic maldevelopment
    Harriette T F M Verzijl
    Department of Neurology, University Medical Center Nijmegen, The Netherlands
    Neurology 61:327-33. 2003
  8. ncbi Agreement between ambulance paramedic- and physician-recorded neurological signs with Face Arm Speech Test (FAST) in acute stroke patients
    A Mohd Nor
    The Freeman Hospital Stroke Service, Royal Bournemouth and Christchurch Hospital, Dorset, UK
    Stroke 35:1355-9. 2004
  9. ncbi The prevalence, predictors, and consequences of peripheral sensory neuropathy in older patients
    James W Mold
    Department of Family and Preventive Medicine, University of Oklahoma Health Sciences Center, Oklahoma City 73104, USA
    J Am Board Fam Pract 17:309-18. 2004
  10. ncbi Amplitude-integrated electroencephalography coupled with an early neurologic examination enhances prediction of term infants at risk for persistent encephalopathy
    Lina F Shalak
    Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9063, USA
    Pediatrics 111:351-7. 2003

Detail Information

Publications337 found, 100 shown here

  1. ncbi Factor structure of the Neurological Evaluation Scale in a predominantly African American sample of patients with schizophrenia, unaffected relatives, and non-psychiatric controls
    Michael T Compton
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 49 Jesse Hill Jr Drive, S E, Atlanta, GA 30303, USA
    Schizophr Res 84:365-77. 2006
    ..This study aimed to identify latent factors of the most widely used scale to measure neurological soft signs, the Neurological Evaluation Scale (NES), in a sample of schizophrenia patients, their relatives, and non-psychiatric controls...
  2. ncbi Distal symmetric polyneuropathy: a definition for clinical research: report of the American Academy of Neurology, the American Association of Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation
    J D England
    Neurology 64:199-207. 2005
    ..The inclusion of this formalized case definition in clinical and epidemiologic research studies will ensure greater consistency of case selection...
  3. ncbi Neurodevelopmental and functional outcomes of extremely low birth weight infants in the National Institute of Child Health and Human Development Neonatal Research Network, 1993-1994
    B R Vohr
    Women and Infants Hospital, Providence, Rhode Island 02905, USA
    Pediatrics 105:1216-26. 2000
    ....
  4. pmc The modified bradykinesia rating scale for Parkinson's disease: reliability and comparison with kinematic measures
    Dustin A Heldman
    Division of Movement Disorders, Cleveland Medical Devices, Inc, Cleveland, Ohio, USA
    Mov Disord 26:1859-63. 2011
    ..Kinematic sensors can accurately quantify speed, amplitude, and rhythm to aid in the development and evaluation of novel therapies in Parkinson's disease...
  5. doi Neonatal brain structure on MRI and diffusion tensor imaging, sex, and neurodevelopment in very-low-birthweight preterm children
    Jessica Rose
    Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA, USA
    Dev Med Child Neurol 51:526-35. 2009
    ..Results indicate that the higher incidence of abnormal neurodevelopment in preterm males relates to greater incidence and severity of brain abnormalities, including reduced PLIC and splenium development...
  6. ncbi Does the National Institutes of Health Stroke Scale favor left hemisphere strokes? NINDS t-PA Stroke Study Group
    D Woo
    Department of Neurology, University of Cincinnati, Cincinnati, Ohio 45220, USA
    Stroke 30:2355-9. 1999
    ..Of 42 possible points, 7 points are directly related to measurement of language compared with only 2 points related to neglect...
  7. ncbi Möbius syndrome redefined: a syndrome of rhombencephalic maldevelopment
    Harriette T F M Verzijl
    Department of Neurology, University Medical Center Nijmegen, The Netherlands
    Neurology 61:327-33. 2003
    ..To investigate the variable clinical picture of Möbius syndrome (MIM no. 157900) and to further understand the pathogenesis of the disorder...
  8. ncbi Agreement between ambulance paramedic- and physician-recorded neurological signs with Face Arm Speech Test (FAST) in acute stroke patients
    A Mohd Nor
    The Freeman Hospital Stroke Service, Royal Bournemouth and Christchurch Hospital, Dorset, UK
    Stroke 35:1355-9. 2004
    ....
  9. ncbi The prevalence, predictors, and consequences of peripheral sensory neuropathy in older patients
    James W Mold
    Department of Family and Preventive Medicine, University of Oklahoma Health Sciences Center, Oklahoma City 73104, USA
    J Am Board Fam Pract 17:309-18. 2004
    ..The prevalence, predictors, and consequences of peripheral neuropathy in the elderly have not been well defined...
  10. ncbi Amplitude-integrated electroencephalography coupled with an early neurologic examination enhances prediction of term infants at risk for persistent encephalopathy
    Lina F Shalak
    Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9063, USA
    Pediatrics 111:351-7. 2003
    The objectives of this study were to determine, first, whether an early neurologic examination could predict a persistent abnormal neonatal neurologic state comparable to the amplitude-integrated electroencephalography (a-EEG) and, second,..
  11. ncbi Preparing for preventive clinical trials: the Predict-HD study
    Jane S Paulsen
    Department of Psychiatry, University of Iowa, Iowa City 52242 1000, USA
    Arch Neurol 63:883-90. 2006
    ..The optimal design and outcome measures for preventive clinical trials in neurodegenerative diseases are unknown...
  12. doi Does clinical rapid eye movement behavior disorder predict worse outcomes in Parkinson's disease?
    S Lavault
    Unité des pathologies du sommeil, Assistance Publique Hopitaux de Paris APHP, Paris, France
    J Neurol 257:1154-9. 2010
    ..The fluctuation and disappearance of clinical RBD in some patients may be due to functional abnormalities rather than lesions...
  13. ncbi Symptom scoring systems to diagnose distal polyneuropathy in diabetes: the Diabetic Neuropathy Symptom score
    J W G Meijer
    Rehabilitation CentreTolbrug Jeroen Bosch Hospital, Den Bosch, The Netherlands
    Diabet Med 19:962-5. 2002
    ..We validated a new four-item Diabetic Neuropathy Symptom (DNS) score for diagnosing distal diabetic polyneuropathy...
  14. doi Common interlimb asymmetries and neurogenic responses during upper limb neurodynamic testing: implications for test interpretation
    Benjamin S Boyd
    Department of Physical Therapy, Samuel Merritt University, Oakland, California, USA
    J Hand Ther 25:56-63; quiz 64. 2012
    ..Clinical measurement pilot study...
  15. doi The quality of preterm infants' spontaneous movements: an early indicator of intelligence and behaviour at school age
    Phillipa R Butcher
    Clinical and Developmental NeuroPsychology, University of Groningen, The Netherlands
    J Child Psychol Psychiatry 50:920-30. 2009
    ..This study investigated whether early spontaneous movements also have predictive value for the intellectual and behavioural problems that children born very preterm often experience...
  16. doi Early systemic hypotension and vasopressor support in low birth weight infants: impact on neurodevelopment
    Adelina Pellicer
    La Paz University Hospital, Department of Neonatology, Paseo de Castellana 261, E 28046 Madrid, Spain
    Pediatrics 123:1369-76. 2009
    ..However, there has been no prospective information on cardiovascular support for hypotension and morbidity...
  17. pmc Natural history of denervation in SMA: relation to age, SMN2 copy number, and function
    Kathryn J Swoboda
    Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Ann Neurol 57:704-12. 2005
    ..These data highlight the potential value of such measures in increasing our understanding of pathophysiological factors involved in denervation in SMA...
  18. ncbi Carpal tunnel syndrome with normal nerve conduction studies
    John C Witt
    Department of Neurology, Mayo Clinic, Scottsdale, Arizona, USA
    Muscle Nerve 29:515-22. 2004
    ..We concluded that NCS provide independent information in the evaluation of suspected CTS, especially when fewer clinical criteria are present, but that NCS are not helpful in predicting the outcome of nonsurgical management...
  19. ncbi Test-retest reliability of the unified Parkinson's disease rating scale in patients with early Parkinson's disease: results from a multicenter clinical trial
    Andrew Siderowf
    Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Mov Disord 17:758-63. 2002
    ..The findings are in agreement with previous reports on interrater reliability...
  20. ncbi Prevalence of movement disorders in men and women aged 50-89 years (Bruneck Study cohort): a population-based study
    Gregor K Wenning
    Department of Neurology, Medical University Innsbruck, Innsbruck, Austria
    Lancet Neurol 4:815-20. 2005
    ..We sought to assess the prevalence of all common categories of movement disorders in a population, accounting for sex differences and age trends...
  21. ncbi The qualitative assessment of general movements in preterm, term and young infants--review of the methodology
    C Einspieler
    Department of Physiology, Karl Franzens University, Graz, Austria
    Early Hum Dev 50:47-60. 1997
    ..This phenomenon is explained by spontaneous recovery of early dysfunction. In contrast, consistent abnormalities of general movements are linked to neurological deficits found at the 2 year follow-up...
  22. ncbi Neurodevelopmental outcome of infants treated with head cooling and mild hypothermia after perinatal asphyxia
    M R Battin
    Newborn Service, National Women s Hospital, Auckland, New Zealand
    Pediatrics 107:480-4. 2001
    ..To determine the neurodevelopmental outcome of infants treated with head cooling with systemic hypothermia after hypoxic-ischemic encephalopathy...
  23. ncbi A comparison of psychometric properties of the smart balance master system and the postural assessment scale for stroke in people who have had mild stroke
    Chi Wen Chien
    School of Occupational Therapy, College of Medicine, National Taiwan University, and Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan
    Arch Phys Med Rehabil 88:374-80. 2007
    ....
  24. ncbi Are neurologic examination abnormalities heritable? A preliminary study
    R D Sanders
    Dayton VA, Dayton, OH, USA
    Schizophr Res 86:172-80. 2006
    b>Neurologic examination abnormalities (NEA) are more prevalent among patients with schizophrenia as well as their unaffected relatives when compared with healthy controls, suggesting that NEA may be endophenotypes for schizophrenia...
  25. pmc Diagnostic value of history and physical examination in patients suspected of lumbosacral nerve root compression
    P C A J Vroomen
    Department of Neurology, Maastricht University Hospital, Maastricht, The Netherlands
    J Neurol Neurosurg Psychiatry 72:630-4. 2002
    ..To evaluate patient characteristics, symptoms, and examination findings in the clinical diagnosis of lumbosacral nerve root compression causing sciatica...
  26. doi Diffusion abnormalities in the primary sensorimotor pathways in writer's cramp
    Christine Delmaire
    Department of Neuroradiology, Centre Hospitalier Régional Universitaire Roger Salengro, Lille, France
    Arch Neurol 66:502-8. 2009
    ..Recent studies have shown structural changes in these regions in writer's cramp...
  27. doi Impaired eye movements in post-concussion syndrome indicate suboptimal brain function beyond the influence of depression, malingering or intellectual ability
    Marcus H Heitger
    Van der Veer Institute for Parkinson s and Brain Research, 66 Stewart Street, Christchurch 8011, New Zealand
    Brain 132:2850-70. 2009
    ..Measurement of oculomotor function may be of value in PCS cases with a high symptom load but an otherwise unremarkable assessment profile. Routine oculomotor testing should be feasible in centres with existing access to this technology...
  28. ncbi Testing forelimb placing "across the midline" reveals distinct, lesion-dependent patterns of recovery in rats
    Martin T Woodlee
    Institute for Neuroscience, The University of Texas at Austin, Austin, TX 78712, USA
    Exp Neurol 191:310-7. 2005
    ..Unlike other tests, cross-midline placing methods can readily distinguish between severe stroke and severe parkinsonism in rats...
  29. ncbi The neurologic examination and neurodiagnostic techniques for reptiles
    Christopher L Mariani
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606 1428, USA
    Vet Clin North Am Exot Anim Pract 10:855-91, vii. 2007
    This article will focus on specifics of performing the neurologic examination and neurodiagnostic testing in reptiles, and how these examinations differ from those performed in more conventional species...
  30. ncbi Monotonicity of nerve tests in diabetes: subclinical nerve dysfunction precedes diagnosis of polyneuropathy
    Peter J Dyck
    Department of Neurology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA
    Diabetes Care 28:2192-200. 2005
    ..The objective of this study was to test whether monotone worsening of nerve function, attributable to diabetes, can be demonstrated before criteria for diabetic sensorimotor polyneuropathy (DSPN) have been met. Which nerve tests are best?..
  31. ncbi Atypical progressive supranuclear palsy underlying progressive apraxia of speech and nonfluent aphasia
    K A Josephs
    Department of Neurology, Division of Behavioural Neurology, Mayo Clinic, Mayo Foundation, Rochester, MN 55905, USA
    Neurocase 11:283-96. 2005
    ..These cases demonstrate that atypical PSP can present as AOS and PNFA without the classic features of PSP...
  32. doi Comparison of 12, 24 and 48 h of systemic hypothermia on outcome after permanent focal ischemia in rat
    Darren L Clark
    Center for Neuroscience, University of Alberta, Edmonton, Alberta, Canada
    Exp Neurol 212:386-92. 2008
    ..4% in rats cooled for one day), but for this there were no significant duration effects. In summary, prolonged hypothermia treatment provides superior protection overall, but this is not explained by reductions in edema...
  33. ncbi Growth and neurodevelopmental outcomes after early low-dose hydrocortisone treatment in extremely low birth weight infants
    Kristi L Watterberg
    Department of Pediatrics Neonatology, MSC10 5590, 1 University of New Mexico School of Medicine, Albuquerque, NM 87131 0001, USA
    Pediatrics 120:40-8. 2007
    ..Mortality and bronchopulmonary dysplasia were decreased in the hydrocortisone-treated patients exposed to chorioamnionitis. We now report outcomes at 18 to 22 months' corrected age...
  34. ncbi Comparative study of the cutaneous sensation of leprosy-suspected lesions using Semmes-Weinstein monofilaments and quantitative thermal testing
    Manoel F Villarroel
    Programa de Pós Graduação em Ciências da Saúde Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
    Lepr Rev 78:102-9. 2007
    ..Despite a higher sensitivity to thermal tests, the SWM has adequate validity as a screening tool in the diagnosis of cutaneous forms of leprosy and in the selection of patients who should be submitted to a more detailed examination...
  35. ncbi Progression of putaminal degeneration in multiple system atrophy: a serial diffusion MR study
    Klaus Seppi
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Neuroimage 31:240-5. 2006
    ....
  36. pmc Disparities in the prevalence of cognitive delay: how early do they appear?
    Marianne M Hillemeier
    Department of Health Policy and Administration, Pennsylvania State University, University Park, PA 16802, USA
    Paediatr Perinat Epidemiol 23:186-98. 2009
    ..Further investigation of processes whereby social disadvantage adversely affects development prior to 24 months is needed...
  37. ncbi Neurologic examination in infants with hypoxic-ischemic encephalopathy at age 9 to 14 months: use of optimality scores and correlation with magnetic resonance imaging findings
    L Haataja
    Department of Paediatrics, Hammersmith Hospital, London, United Kingdom
    J Pediatr 138:332-7. 2001
    OBJECTIVES: To evaluate whether a structured and scorable neurologic examination (The Hammersmith Infant Neurological Examination) correlates with early magnetic resonance imaging findings in a group of infants with hypoxic-ischemic ..
  38. ncbi A 3-year prospective study of neurological soft signs in first-episode schizophrenia
    Eric Yu Hai Chen
    Department of Psychiatry, University of Hong Kong Queen Mary Hospital, Pokfulam Road, Hong Kong
    Schizophr Res 75:45-54. 2005
    ..A higher level of neurological soft signs is related to a lower educational level and an older age at onset, but the level of neurological soft signs does not predict the outcome in terms of relapse or occupational functioning...
  39. ncbi Detection of small-fiber neuropathy by sudomotor testing
    Victoria A Low
    Department of Neurology, Mayo Clinic, Guggenheim 811, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 34:57-61. 2006
    ..Sudomotor examination is thus a highly sensitive detection tool in DSFN. Autonomic involvement is mainly distal, and additionally may involve adrenergic and the long cardiovagal fibers...
  40. ncbi Neurological signs and psychomotor performance in patients with schizophrenia, their relatives and healthy controls
    L Flyckt
    Department of Psychiatry, Karolinska Institute, Danderyd s Hospital, Stockholm, Sweden
    Psychiatry Res 86:113-29. 1999
    ..These findings indicate that neurological aberrations are present at the onset of illness and that hereditary factors are associated with motor laterality...
  41. ncbi Should the Babinski sign be part of the routine neurologic examination?
    Timothy M Miller
    Department of Neurology, University of California, San Francisco, CA, USA
    Neurology 65:1165-8. 2005
    ..sign of upper motor neuron dysfunction that is widely considered an essential element of a complete neurologic examination. Little is known about reliability and validity of this sign...
  42. ncbi Accuracy of acute levodopa challenge for clinical prediction of sustained long-term levodopa response as a major criterion for idiopathic Parkinson's disease diagnosis
    Marcelo Merello
    Movement Disorders Section, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, Argentina
    Mov Disord 17:795-8. 2002
    ..5% in Group III. The positive result of initial acute L-dopa challenge predicts chronic L-dopa responsiveness as major criterion of PD in all patients with UPDRS motor scores lower than 10...
  43. ncbi Neurological impairment in rats after transient middle cerebral artery occlusion: a comparative study under various treatment paradigms
    S Zausinger
    Department of Neurosurgery, Ludwig Maximilians Universitat, Klinikum Grosshadern, Marchioninistr 15, 81377, Munich, Germany
    Brain Res 863:94-105. 2000
    ..The functional impairment from focal brain ischemia and its subsequent recovery could provide valuable information for future studies evaluating the neuroprotective potential of novel agents and procedures...
  44. ncbi Diagnosing carpal tunnel syndrome--clinical criteria and ancillary tests
    Einar P Wilder-Smith
    Neurophysiological Section, National University Hospital, Singapore
    Nat Clin Pract Neurol 2:366-74. 2006
    ..Supplementary tests of small nerve fiber function and measurement of intracarpal pressure might, in the future, improve early recognition of CTS, especially in the absence of well-defined symptoms...
  45. ncbi Can the frontal assessment battery (FAB) differentiate bradykinetic rigid syndromes? Relation of the FAB to formal neuropsychological testing
    D C Paviour
    The Sara Koe PSP Research Centre, Institute of Neurology, London, UK
    Neurocase 11:274-82. 2005
    ..These results suggest that the FAB is a valid and easily applicable bedside test to discriminate executive dysfunction in these three frequently confused bradykinetic rigid syndromes...
  46. ncbi Neurological manifestations of Hansen's disease and their management
    Amit Agrawal
    Department of Neurosurgery, K S Hegde Medical Academy, Deralakatte 575018, Mangalore, Karnataka, India
    Clin Neurol Neurosurg 107:445-54. 2005
    ..In this article we review the literature and discuss the pathology, clinical features, diagnosis and management of neurological manifestations of leprosy...
  47. ncbi H-reflex latency and nerve root tension sign correlation in fluoroscopically guided, contrast-confirmed, translaminar lumbar epidural steroid-bupivacaine injections
    Michael F Stretanski
    Surgical Neurology of North Central Ohio, Mansfield, OH, USA
    Arch Phys Med Rehabil 85:1479-82. 2004
    ....
  48. ncbi Neurological abnormalities in cognitively impaired but not demented elderly
    T Kumamoto
    Third Department of Internal Medicine, Oita Medical University, Japan
    Acta Neurol Scand 102:292-8. 2000
    ..We determined the prevalence and clinical characteristics of elderly people with cognitively impaired but not demented (CIND) in the community...
  49. ncbi Does a detailed assessment of poor repertoire general movements help to identify those infants who will develop normally?
    Yayohi Nakajima
    Institute of Physiology, Developmental Physiology and Developmental Neurology, Center for Physiological Medicine, Medical University of Graz, Harrachgasse 21 5, A 8010 Graz, Austria
    Early Hum Dev 82:53-9. 2006
    ..Poor repertoire GMs are the most frequently observed abnormal GMs during the preterm, term and early postterm period. However, their predictive value for the neurological outcome is low...
  50. ncbi The role of spontaneous general movement assessment in the neurological outcome of cerebral lesions in preterm infants
    Juliana M Garcia
    Department of Neurology and Pediatrics, Hospital das Clinicas, School of Medicine, Universidade de Sao Paulo USP, Sao Paulo, SP, Brazil
    J Pediatr (Rio J) 80:296-304. 2004
    ..To study the relationship among the quality, type, and trajectory of general movements in preterm infants and neonatal cranial ultrasonography findings and neurological outcome...
  51. ncbi The six spot step test: a new measurement for walking ability in multiple sclerosis
    M M Nieuwenhuis
    Department of Neurology, Copenhagen MS Research Centre, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Mult Scler 12:495-500. 2006
    ..For this purpose, we developed the Six Spot Step Test (SSST), which besides speed includes co-ordination and balance, to be a lower limb counterpart to the 9-Hole Peg Test (9HPT)...
  52. ncbi Gait dynamics in Parkinson's disease: relationship to Parkinsonian features, falls and response to levodopa
    Joanna D Schaafsma
    Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, and Sackler School of Medicine, Tel Aviv University, 6 Weizmann Street, Tel Aviv 64239, Israel
    J Neurol Sci 212:47-53. 2003
    ....
  53. ncbi Somatosensory stimulation enhances the effects of training functional hand tasks in patients with chronic stroke
    Pablo Celnik
    Human Cortical Physiology Section and Stroke Neurorehabilitation Clinic, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Arch Phys Med Rehabil 88:1369-76. 2007
    ..To test the hypothesis that somatosensory stimulation would enhance the effects of training functional hand tasks immediately after practice and 1 day later in chronic subcortical stroke patients...
  54. doi Neurological soft signs in patients with schizophrenia and their unaffected siblings: frequency and correlates in two ethnic and socioeconomic distinct populations
    Anwar Mechri
    Research Laboratory Vulnerability to Psychotic Disorders, Department of Psychiatry, University Hospital of Monastir, 5000, Monastir, Tunisia
    Eur Arch Psychiatry Clin Neurosci 259:218-26. 2009
    ..These studies provide a confirmation in two distinct samples of the high prevalence of NSS in patients with schizophrenia, and in their biological relatives, independently of their respective ethnic and socioeconomic origins...
  55. ncbi Pathophysiology of headache associated with cough in patients with Chiari I malformation
    Charles A Sansur
    Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 1414, USA
    J Neurosurg 98:453-8. 2003
    ..In addition, the authors evaluated the use of intrathecal pressure during cough as a means of assessing obstruction to the free flow of cerebrospinal fluid (CSF) at the craniocervical junction...
  56. ncbi Orofacial apraxia in corticobasal degeneration, progressive supranuclear palsy, multiple system atrophy and Parkinson's disease
    Canan Ozsancak
    Service de Neurologie et Pathologie du Mouvement, EA 2683 Clinique Neurologique, CHU de Lille, 59037, Lille Cedex, France
    J Neurol 251:1317-23. 2004
    ....
  57. doi Sensory testing of inferior alveolar nerve injuries: a review of methods used in prospective studies
    Lucas J Poort
    Department of Oral and Maxillofacial Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    J Oral Maxillofac Surg 67:292-300. 2009
    ..So far there is no consensus for evaluating IAN injury. This study aimed to identify a testing method suitable for daily clinical practice which allows us to identify nerve injury, grade its severity, and monitor its recovery...
  58. ncbi Parry-Romberg syndrome with a clinically silent white matter lesion
    A Okumura
    Department of Pediatrics, Nagoya University Graduate School of Medicine, Aichi, Japan
    AJNR Am J Neuroradiol 27:1729-31. 2006
    ..Pyramidal tracts and optic radiations were preserved on diffusion tensor tractography. We will correlate these neuroimaging findings with normal psychomotor development in our patient...
  59. ncbi Prevalence and severity of gait disorders in Alzheimer's and non-Alzheimer's dementias
    Louise M Allan
    Institute for Aging and Health, University of Newcastle upon Tyne, United Kingdom
    J Am Geriatr Soc 53:1681-7. 2005
    ....
  60. pmc Diagnostic accuracy of the vegetative and minimally conscious state: clinical consensus versus standardized neurobehavioral assessment
    Caroline Schnakers
    Coma Science Group, Cyclotron Research Center, University of Liege, Belgium
    BMC Neurol 9:35. 2009
    ..In this study, we compared consensus-based diagnoses of VS and MCS to those based on a well-established standardized neurobehavioral rating scale, the JFK Coma Recovery Scale-Revised (CRS-R)...
  61. pmc Using videotaped vignettes to teach medical students to perform the neurologic examination
    Erle C H Lim
    J Gen Intern Med 21:101. 2006
  62. ncbi Comparisons of patient self-report, neurologic examination, and functional impairment in MS
    E L Hoogervorst
    Department of Neurology, Academic Hospital, Free University, Amsterdam, The Netherlands
    Neurology 56:934-7. 2001
    ..Guy's Neurologic Disability Scale (GNDS), based on patient self-report, with both neurologist rating of neurologic examination abnormalities using the Expanded Disability Status Scale (EDSS) and observations of functional impairment ..
  63. ncbi Neurophysiologic and quantitative sensory testing in the diagnosis of trigeminal neuropathy and neuropathic pain
    Satu K Jääskeläinen
    Department of Clinical Neurophysiology, Turku University Hospital, P O Box 52, FIN 20521 Turku, Finland
    Pain 117:349-57. 2005
    ..012). Neurophysiologic tests and thermal QST provide sensitive tools for accurate diagnosis of trigeminal neuropathy and study of pathophysiological features characteristic to human neuropathic pain...
  64. ncbi Overview on tools and methods to assess neuropathic trigeminal pain
    Peter Svensson
    Department of Clinical Oral Physiology, Royal Dental College, University of Aarhus, Aarhus, Denmark
    J Orofac Pain 18:332-8. 2004
    ..There is also a need for common guidelines on classification, diagnostic procedures, and management. This will require concerted international, interdisciplinary action...
  65. doi Bilateral coordination of gait and Parkinson's disease: the effects of dual tasking
    M Plotnik
    Laboratory for Gait and Neurodynamics, Movement Disorders Unit, Tel Aviv Sourasky Medical Center, 6 Weizmann St, Tel Aviv, 64239, Israel
    J Neurol Neurosurg Psychiatry 80:347-50. 2009
    ..The present findings suggest that in patients with PD, cognitive resources are used in order to maintain consistent and accurate alternations in left-right stepping...
  66. pmc Diagnostic accuracy of the neurological upper limb examination I: inter-rater reproducibility of selected findings and patterns
    Jorgen R Jepsen
    Department of Occupational Medicine, Sydvestjysk Sygehus, Østergade 81 83, DK 6700 Esbjerg, Denmark
    BMC Neurol 6:8. 2006
    ..The reproducibility of this part of the neurological examination has never been reported...
  67. ncbi Gait asymmetry in patients with Parkinson's disease and elderly fallers: when does the bilateral coordination of gait require attention?
    Galit Yogev
    Movement Disorders Unit, Neurology Department, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel
    Exp Brain Res 177:336-46. 2007
    ..In contrast, however, when gait becomes impaired and less automatic, GA apparently relies on cognitive input and attention...
  68. doi Frontal release signs among patients with schizophrenia, their first-degree biological relatives, and non-psychiatric controls
    Megan K Gabalda
    Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, Atlanta, GA 30303, USA
    Schizophr Res 106:275-80. 2008
    ....
  69. pmc Neurological soft signs in schizophrenia: a meta-analysis
    Raymond C K Chan
    Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, 4A Datun Road, Beijing 100101, China
    Schizophr Bull 36:1089-104. 2010
    ..A systematic search was conducted for published articles reporting NSS and related data using standard measures in schizophrenia and healthy comparison groups...
  70. doi Quantitative sensory testing in measurement of neuropathic pain phenomena and other sensory abnormalities
    Miroslav Misha Backonja
    Department of Neurology, University of Wisconsin Madison, 600 Highland Avenue, Madison, WI 53792, USA
    Clin J Pain 25:641-7. 2009
    ..Together with the companion manuscript, this review provides definitions that should help further the use of QST as a diagnostic tool as well...
  71. ncbi The effects of occupational exposure to chlorpyrifos on the neurologic examination of central nervous system function: a prospective cohort study
    James W Albers
    Department of Neurology, University of Michigan Health Systems, Ann Arbor 48109 0032, USA
    J Occup Environ Med 46:367-78. 2004
    ....
  72. doi Surgical risk factors and maxillary nerve function after Le Fort I osteotomy
    Torben H Thygesen
    Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, University of Aarhus, Aarhus, Denmark
    J Oral Maxillofac Surg 67:528-36. 2009
    ..The aim of this study was to describe prospectively the overall postoperative changes in maxillary nerve function after LFO, and to correlate these changes with a number of possible intraoperative risk factors...
  73. doi Use of the GMFCS in infants with CP: the need for reclassification at age 2 years or older
    Jan Willem Gorter
    CanChild Centre for Childhood Disability Research, McMaster University, Hamilton, Ontario, Canada
    Dev Med Child Neurol 51:46-52. 2009
    ..In conclusion, children can be classified by the GMFCS early on, but there is a need for reclassification at age 2 or older as more clinical information becomes available...
  74. doi How to detect a sensory abnormality
    Rolf Detlef Treede
    Eur J Pain 12:395-6. 2008
  75. pmc Diagnostic accuracy of the neurological upper limb examination II: relation to symptoms of patterns of findings
    Jørgen R Jepsen
    Department of Occupational Medicine, Sydvestjysk Sygehus, Østergade 81 83, DK 6700 Esbjerg, Denmark
    BMC Neurol 6:10. 2006
    ..This further study aimed at approaching the diagnostic accuracy of the examination...
  76. ncbi Application of a scorable neurological examination to near-term infants: longitudinal data
    D M M Romeo
    Department of Paediatrics, University of Catania, Catania, Italy
    Neuropediatrics 38:233-8. 2007
    ..Our results, providing longitudinal data in near-term infants without brain lesions, can be used as a reference in both clinical and research setting to monitor early neurological signs in those children...
  77. doi Parkinson's disease: clinical features and diagnosis
    J Jankovic
    Department of Neurology, Parkinson s Disease Center and Movement Disorders Clinic, Baylor College of Medicine, 6550 Fannin, Suite 1801, Houston, Texas 77030 3498, USA
    J Neurol Neurosurg Psychiatry 79:368-76. 2008
    ..This review describes the clinical characteristics of PD with emphasis on those features that differentiate the disease from other parkinsonian disorders...
  78. ncbi Neurologic examination abnormalities in children with bipolar disorder or attention-deficit/hyperactivity disorder
    Daniel P Dickstein
    National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, 10 Center Drive MSC 1255, Building 10 Room 4N208, Bethesda MD 20892 1255, USA
    Biol Psychiatry 58:517-24. 2005
    ..To move beyond diagnosis toward unique pathophysiology, we evaluated both ADHD and BPD children for neurologic examination abnormalities (NEAs) in comparison with normal control (NC) children.
  79. ncbi MEK1/2 inhibition attenuates vascular ETA and ETB receptor alterations after cerebral ischaemia
    Marie Henriksson
    Division of Experimental Vascular Research, Department of Clinical Sciences in Lund, BMC A13, Lund University, Lund, 221 84 Sweden
    Exp Brain Res 178:470-6. 2007
    ..The vascular effects of U0126 provide new perspective on possible mechanisms of actions of MAPK inhibition in cerebral ischaemia...
  80. doi Assessment of trigeminal nerve functions by quantitative sensory testing in patients and healthy volunteers
    Sareh Said Yekta
    Department of Conservative Dentistry, Periodontology and Preventive Dentistry, Aachen University, Aachen, Germany
    J Oral Maxillofac Surg 68:2437-51. 2010
    ..Orofacial sensory dysfunction plays an important role in oral and maxillofacial surgery. Quantitative sensory testing (QST) is a psychophysical approach to evaluate thermal and mechanical somatosensation...
  81. ncbi EFNS guidelines on neuropathic pain assessment
    G Cruccu
    EFNS Panel on Neuropathic Pain Department of Neurological Sciences, La Sapienza University, Rome, Italy
    Eur J Neurol 11:153-62. 2004
    ..A laboratory measure of pain that by-passes the subjective report, and thus cognitive influences, is a hopeful aim for the future...
  82. doi The Neuropad test: a visual indicator test for human diabetic neuropathy
    C Quattrini
    Division of Cardiovascular Medicine, Core Technology Facility, University of Manchester, 46 Grafton Street, Manchester M13 9NT, UK
    Diabetologia 51:1046-50. 2008
    ..It uses a colour change to define the integrity of skin sympathetic cholinergic innervation. We compared the results of Neuropad assessment in the foot with established measures of somatic and autonomic neuropathy...
  83. ncbi The avian neurologic examination and ancillary neurodiagnostic techniques: a review update
    Tracy L Clippinger
    Department of Veterinary Services, Zoological Society of San Diego San Diego Zoo, 1354 Old Globe Way, San Diego, CA 92101 1635, USA
    Vet Clin North Am Exot Anim Pract 10:803-36, vi. 2007
    ..muscle and nerve histology, and electrodiagnostics, are tools to confirm and clarify conclusions from the neurologic examination and to identify the cause of disease...
  84. ncbi Validation and factorial structure of a standardized neurological examination assessing neurological soft signs in schizophrenia
    M O Krebs
    Laboratoire de Psychiatrie Biologique Université Paris V, Service Hospitalo Universitaire de Santé Mentale et Thérapeutique, Centre Hospitalier Sainte Anne, Paris, France
    Schizophr Res 45:245-60. 2000
    ..This scale thus confirmed a factorial structure in agreement with the conceptual areas of interest explored by NSS and should be a useful tool for assessment of the different dimensions of neurological dysfunction in schizophrenia...
  85. doi The quality of the early motor repertoire in preterm infants predicts minor neurologic dysfunction at school age
    Janneke L M Bruggink
    Department of Pediatrics, Division of Neonatology, Beatrix Children s Hospital, University Medical Center Groningen, Groningen, The Netherlands
    J Pediatr 153:32-9. 2008
    ..Its predictive power for minor neurologic dysfunction (MND) is unclear. This study aimed to investigate the predictive value of the quality of the early motor repertoire for the development of MND at school age...
  86. pmc Signs and symptoms versus nerve conduction studies to diagnose diabetic sensorimotor polyneuropathy: Cl vs. NPhys trial
    Peter J Dyck
    Peripheral Neuropathy Research Laboratory, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 42:157-64. 2010
    ..Study physician dx from signs and symptoms were excessively variable, often overestimating DSPN. Specific approaches to improving clinical proficiency should be tested...
  87. doi A systematic review of the clinimetric properties of neuromotor assessments for preterm infants during the first year of life
    Alicia J Spittle
    Victorian Infant Brain Studies, Murdoch Childrens Research Institute, Parkville, Melbourne, Australia
    Dev Med Child Neurol 50:254-66. 2008
    ..85). Selection of motor assessment tools during the first year of life for infants born preterm will depend on the intended purpose of their use for discrimination, prediction, and/or evaluation...
  88. pmc Predictive value of an early amplitude integrated electroencephalogram and neurologic examination
    Seetha Shankaran
    Department of Pediatrics, Wayne State University, Detroit, Michigan, USA
    Pediatrics 128:e112-20. 2011
    ..To examine the predictive validity of the amplitude integrated electroencephalogram (aEEG) and stage of encephalopathy among infants with hypoxic-ischemic encephalopathy (HIE) eligible for therapeutic whole-body hypothermia...
  89. doi Acupuncture for chemotherapy-induced peripheral neuropathy (CIPN): a pilot study using neurography
    Sven Schroeder
    HanseMerkur Centre for TCM at the University Medical Center, UKE Campus, House O55, Martinistrasse 52, 20246, Hamburg, Germany
    Acupunct Med 30:4-7. 2012
    ..Specific and effective curative treatments are lacking...
  90. doi Neurological soft signs as candidate endophenotypes for schizophrenia: a shooting star or a Northern star?
    Raymond C K Chan
    Neuropsychology and Applied Cognitive Neuroscience Laboratory, Institute of Psychology, Chinese Academy of Sciences, Beijing, China
    Neurosci Biobehav Rev 32:957-71. 2008
    ..Finally, we recommend areas in which additional research should be done to further elucidate the potential use of neurological soft signs for schizophrenia research...
  91. ncbi Prechtl's assessment of general movements: a diagnostic tool for the functional assessment of the young nervous system
    Christa Einspieler
    Institute of Physiology, Center for Physiological Medicine, Medical University of Graz, Graz, Austria
    Ment Retard Dev Disabil Res Rev 11:61-7. 2005
    ..g., magnetic resonance imaging, brain ultrasound, and traditional neurological examination...
  92. doi Correlation of quantitative sensorimotor tractography with clinical grade of cerebral palsy
    Richa Trivedi
    Department of Radiodiagnosis, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226014, India
    Neuroradiology 52:759-65. 2010
    ....
  93. ncbi Early neurologic assessment in preterm-infants: integration of traditional neurologic examination and observation of general movements
    Domenico Marco Maurizio Romeo
    Division of Child Neurology and Psychiatry, Department of Paediatrics, University of Catania, Italy
    Eur J Paediatr Neurol 12:183-9. 2008
    ..benefit in terms of prognostic accuracy of an integrated application of a traditional scorable method of neurologic examination and the Prechtl's method of qualitative assessment of general movements (GMs) in a large population of 903 ..
  94. doi Postural instability and fall risk in Parkinson's disease: impaired dual tasking, pacing, and bilateral coordination of gait during the "ON" medication state
    Meir Plotnik
    Laboratory for Gait and Neurodynamics, Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, 64239, Tel Aviv, Israel
    Exp Brain Res 210:529-38. 2011
    ..These cognitive and motor deficits may increase the likelihood of loss of balance during everyday attention-demanding tasks among patients with PD...
  95. ncbi Impaired warm and cold perception thresholds in leprosy skin lesions
    Manoel F Villarroel
    Programa de Pós Graduação em Ciências da Saúde Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
    Lepr Rev 78:110-21. 2007
    ....
  96. doi Progressive apraxia of speech presenting as isolated disorder of speech articulation and prosody: a case report
    M Ricci
    Unit of Neurology, Regina Apostolorum Hospital, Rome, Italy
    Neurocase 14:162-8. 2008
    ..Our findings highlight the importance of the left hemisphere in speech articulatory deficits and suggest that the left superior frontal gyrus plays a crucial role in specific articulatory processes...
  97. pmc Syndromes of nonfluent primary progressive aphasia: a clinical and neurolinguistic analysis
    Jonathan D Rohrer
    Dementia Research Centre, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    Neurology 75:603-10. 2010
    ..Despite recent work, the nosology of nonfluent primary progressive aphasia (PPA) remains unresolved...
  98. doi Agreement and correlation between the straight leg raise and slump tests in subjects with leg pain
    Jeremy Walsh
    School of Physiotherapy, Royal College of Surgeons in Ireland, Dublin, Ireland
    J Manipulative Physiol Ther 32:184-92. 2009
    ..The aim of this study was to determine agreement and correlation between the SLR and slump tests in a population presenting with back and leg pain...
  99. doi The Groningen ART cohort study: the effects of ovarian hyperstimulation and the IVF laboratory procedures on neurological condition at 2 years
    P Schendelaar
    Division of Developmental Neurology CA 85, Department of Paediatrics, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Hum Reprod 26:703-12. 2011
    ..Our aim was to evaluate the effects of ovarian hyperstimulation, IVF laboratory procedures and a history of subfertility on neurological condition at 2 years...
  100. pmc Headache in Cerebral Venous Thrombosis: incidence, pattern and location in 200 consecutive patients
    Mohammad Wasay
    Department of Medicine Neurology, The Aga Khan University, Karachi, Pakistan
    J Headache Pain 11:137-9. 2010
    ..05). There was no association between lateralization of pain and site of thrombosis (P = 0.66)...
  101. ncbi The utility of median somatosensory evoked potentials in anoxic-ischemic coma
    Ted L Rothstein
    Department of Neurology, Rm 7 402, George Washington University, 2150 Pennsylvania Avenue, NW, Washington, DC 20037, USA
    Rev Neurosci 20:221-33. 2009
    ..Greater use of SSEP in anoxic-ischemic coma would identify those patients unlikely to recover and would avoid costly medical care that is to no avail...

Research Grants75

  1. Early Identification of Developmental Disorders in Infants
    B Eugene Parker; Fiscal Year: 2012
    ....
  2. Neuroimaging and Metabolomics Correlates of Cognitive Decline in Parkinson?s Dise
    Chaorui Huang; Fiscal Year: 2013
    ..These markers can predict dementia at preclinical stage, and serve as surrogate markers of response to promising therapeutic interventions. ..
  3. Nabila Dahodwala; Fiscal Year: 2014
    ..This application will provide critical support for the PI to become an independent researcher and a leader in health services research in aging and neurodegenerative diseases. ..
  4. Early Pesticide Exposure and Neurodevelopmental Outcomes in a Thai Birth Cohort
    P Barry Ryan; Fiscal Year: 2010
    ....
  5. Home Ambulatory EEG with Video Monitoring
    DANIEL S HEDIN; Fiscal Year: 2011
    ..Ambulatory v-EEG carried out in the patient home can provide a large cost savings and patient benefit if size, ease of use, and adequate video issues can be resolved. ..
  6. Early Identification of Developmental Disorders in Infants
    B Parker; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  7. Subsequent effects of manipulating embryonic neuronal activity
    Elwood Albert Linney; Fiscal Year: 2010
    ..The technologies used will include behavioral analyses, the creation and use of a number of fluorescent transgenic reporter lines to fish, microarray analysis, and HPLC analysis of neurotransmitter levels. ..
  8. CLINICAL TRIAL OF HEMATOCRIT STRATEGY IN HEART SURGERY
    Jane Newburger; Fiscal Year: 2004
    ..3) intrinsic cerebral vasoregulation, measured by NIRS and transcranial Doppler; and 4) at age 1 year, neurologic examination, the MacArthur inventory, and structural and volumetric findings on MRI...
  9. Cognitive and Neurologic Sequelae in Cerebral Malaria
    Chandy John; Fiscal Year: 2007
    ..and trainees with courses in clinical areas (malaria pathogenesis; care of the acutely ill child; neurologic examination), neuropschology (assessment of child cognition and development), immunology (host defense and infection, ..
  10. NEUROLOGIC MANIFESTATIONS OF HTLV-I INFECTION
    King Holmes; Fiscal Year: 2000
    ..to HTLV-1 status and will include a simple screening performed by a trained non-physician, a standardized neurologic examination performed by a neurologist, and a quantitative spasticity assessment (QSA) of the lower limbs using a ..
  11. CONTROLLED STUDY OF INFANT HIV ENCEPHALOPATHY
    David Coulter; Fiscal Year: 1992
    ..Epidemiological, relative risk, and statistical (MANOVA with repeated measures) determinations will be used to analyze these results and test the stated hypotheses...
  12. BIOLOGICAL FACTORS RESPONSIBLE FOR NEUROBEHAVIORAL AGING
    CONSTANCE MEYD; Fiscal Year: 1991
    ..Using this approach we hope to determine the important mechanisms responsible for age-related and gender-related differences in verbal memory and learning, motor speed and sensory- motor-performance...
  13. NEUROIMMONOLOGIC STUDIES OF CHRONIC FATIGUE SYNDROME
    Anthony Komaroff; Fiscal Year: 1992
    ..Neurologic evaluation would include a neurologic examination, evoked potentials, lumbar puncture, neuropsychologic testing of mood and cognition, and magnetic ..
  14. MIDCAREER INVESTIGATOR AWARD IN NEURO-AIDS RESEARCH
    David Simpson; Fiscal Year: 2005
    ..The Neuro-Adherence Program will assess the affect of neurological disease on patients' adherence to medical regimens, and the impact of education and support groups on adherence. ..
  15. Developing a pocket neuromuscular evaluator
    Li Qun Zhang; Fiscal Year: 2010
    ..It will provide clinicians a quantitative and convenient tool to evaluate not only neurological reflexes but also the related muscle-joint properties, making the overall neuromuscular evaluations more accurate and reliable. ..
  16. INTRACTABLE EPILEPSY--PRESURGICAL STRATEGY AND OUTCOME
    Frank Gilliam; Fiscal Year: 1999
    ..Phase II statistical analysis will include as appropriate a categorical format (chi square or Fisher's Exact test), repeated measures analysis, interaction assessment, and ANOVA with covariance adjustment. ..
  17. INPATIENT VIOLENCE TRAIT & STATE
    Menahem Krakowski; Fiscal Year: 1993
    ..Data analysis will permit examination of the hypotheses. ..
  18. Neurological Phenotype in FMR1 Premutation Carriers
    Paul Hagerman; Fiscal Year: 2005
    ..The project will also include an analysis of association of the phenotype with a newly described molecular abnormality of the premutation range (elevated FMR1 mRNA). ..
  19. Beta-glucocerebrosidase Mutations and PD in the Ashkenazim
    Lorraine Clark; Fiscal Year: 2006
    ..Significantly, recent studies suggest that mutations in the GBA gene may be associated with Parkinson's disease and the lysosomal/autophagic pathway has also been implicated in PD pathogenesis. [unreadable] [unreadable]..
  20. LONGITUDINAL OPTIC NEURITIS STUDY
    Robin Gal; Fiscal Year: 2006
    ..will be recertified and each patient will be seen for an ocular examination, visual function testing, and neurologic examination by protocols currently utilized in the LONS...
  21. NEUROLOGICAL SEQUELAE:CHRONIC TOLUENE INHALATION ABUSE
    Neil Rosenberg; Fiscal Year: 1991
    ....
  22. NEUROBEHAVIORAL EFFECTS OF ENVIRONMENTAL PCB EXPOSURE
    Philippe Grandjean; Fiscal Year: 1999
    ..Follow-up assessments include at 18 months the Bayley-II, and a neurologic examination at 30 months, with more extensive test batteries at ages 42, 54, and 66 months.
  23. Quantitative Occlusive Vascular Disease Study, QUOVADIS
    Fernando Boada; Fiscal Year: 2009
    ..Baseline neurologic examination, neurologic scoring, and MRI are recorded for prestudy neurologic status and cortical and subcortical ..
  24. Stress and MRI Detectable Lesions in Multiple Sclerosis
    MATTHEW SORENSON; Fiscal Year: 2005
    ..abstract_text> ..
  25. POSTURAL MECHANISMS IN IDIOPATHIC SCOLIOSIS
    EUGENE BLECK; Fiscal Year: 1980
    ..All children with scoliosis will be retested at six month intervals throughout growth (estimated three years) and the results correlated with the radiographic progression or nonprogression of the spinal curvature. ..
  26. INFANT HEART SURGERY--CNS SEQUELAE OF CIRCULATORY ARREST
    Jane Newburger; Fiscal Year: 2001
    ..Previously, the applicants have assessed brain structure via MRI (one year); brain function via neurologic examination, and EEG (preoperatively, one-week postoperatively, and at one and four years); and development (at one ..
  27. NUCLEAR MAGNETIC RESONANCE IN SCHIZOPHRENIA
    MARIAN DEMYER; Fiscal Year: 1990
    ..Results of this five year study using 100 schizophrenic, 100 normal, and 50 depressed subjects should help open increasingly focussed avenues of biological research in schizophrenia...
  28. NEUROPSYCHOLOGY OF MULTIPLE SCLEROSIS
    STEPHEN RAO; Fiscal Year: 1991
    ....
  29. GENETIC SUSCEPTIBILITY IN SCHIZOPHRENIA
    Vishwajit Nimgaonkar; Fiscal Year: 2007
    ..This is a competing supplement for MH 56242, 'Genetic Susceptibility in Schizophrenia'. [unreadable] [unreadable] [unreadable]..
  30. HISPANIC ELDERLY COGNITIVE SCREEN VALIDATION STUDY
    RAMON VALLE; Fiscal Year: 1991
    ..This project is seen as addressing an urgent need for the development of culture free/fair cognitive assessment instrumentation for use with this growing ethnic minority elderly population group...
  31. DEVELOPMENT OF PRE- AND FULL-TERM INFANTS
    T Brazelton; Fiscal Year: 1980
    ....
  32. NEUROPSYCHOLOGY OF MULTIPLE SCLEROSIS
    STEPHEN RAO; Fiscal Year: 1992
    ..be administered a comprehensive battery of cognitive and affective psychometric tests, and will undergo a neurologic examination (including measures of disability), MRI, an audiological examination, a videotaped psychosocial interview, ..
  33. Multiple Factors Affecting Placebo Response in PD
    Christopher Goetz; Fiscal Year: 2004
    ..Defining these determinant influences will help enhance placebo responses in clinical practice and control them in clinical trials. ..
  34. Oxygen and Phototherapy in perinatal period: Risk of Acute Lymphoctyic Leukemia
    Nigel Paneth; Fiscal Year: 2008
    ..If these treatments increase the risk of leukemia, it should be possible to find alternative ways to manage newborn problems that minimize exposure to these treatments [unreadable] [unreadable] [unreadable]..
  35. Vascular and Inflammatory Predictors of MCI Risk and Progression
    ROSEBUD ROBERTS; Fiscal Year: 2008
    ..The K01 award will culminate in an R01 application that will pave the way for the candidate to become an independent investigator in MCI and AD research. [unreadable] [unreadable] [unreadable]..
  36. DBS Effects on Mood and Cognition in Parkinsons Disease
    Michael Okun; Fiscal Year: 2007
    ..This proposal includes active and experienced mentoring, access to diverse resources, and a scientific environment suited specifically for the development of the PI as an independent physician scientist. ..
  37. Outcomes of Perinatal Stroke
    Meredith Golomb; Fiscal Year: 2008
    ..During the last year of the study, she plans to apply for an R01 grant to set up a pilot clinical trial. [unreadable] [unreadable]..
  38. Response of a Sample Population with the Deleterious HD allele RESPOND-HD
    Jane Paulsen; Fiscal Year: 2007
    ..This study will be among the first to compare ethical, legal and social experiences of having known genetic risk. ..
  39. Defibrotide for the treatment of severe hepatic veno-cc*
    Paul Richardson; Fiscal Year: 2007
    ..Abstract Not Provided ..
  40. Racial Disparities in School and Mental Health Services
    Marianne Hillemeier; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  41. Diagnostic Utility of MRI in Intracerebral Hemorrhage
    CHRISTINE A WIJMAN; Fiscal Year: 2010
    ..We anticipate that the findings from this study will have a major impact on the management of ICH patients and will facilitate the development of practice guidelines for the use of MRI in these patients. ..
  42. New Paradigms of Cerebral Palsy Etiology: A Comprehensive Case Control Study
    NIGEL SEFTON PANETH; Fiscal Year: 2010
    ..Maternal interviews and birth certificates will inform the above analyses by linking molecular information to self-reported and recorded clinical events and conditions. ..
  43. Cognitive Effects of Cerebellar Lesions in Humans
    JEREMY SCHMAHMANN; Fiscal Year: 2006
    ..This study has implications for the recognition and treatment of disorders of higher order function in cerebellar patients. [unreadable] [unreadable]..
  44. MULTICENTER NETWORK OF NEONATAL INTENSIVE CARE UNITS
    T O SHEA; Fiscal Year: 2005
    ..abstract_text> ..
  45. NEUROPSYCHOLOGY AND DEMENTIA
    Jane Paulsen; Fiscal Year: 2002
    ..This award will facilitate the candidate's research efforts towards understanding brain-behavior relations in dementia and using this knowledge to assist families and individuals in treatment planning for the future. ..
  46. Genetic Polymorphisms Benign Prostatic Hyperplasia
    ROSEBUD ROBERTS; Fiscal Year: 2004
    ..This community-based cohort study should provide insights that should improve our understanding of the genetic control of hormonal mechanisms in the pathogenesis of BPH. ..
  47. Efferent Vestibular Mechanisms
    MEIR PLOTNIK PELEG; Fiscal Year: 2003
    ..The significance of this research is in setting the foundations of mammalian efferent neuron physiology, and providing experimental data on the control mechanism by which the EVS operates. ..
  48. GENES FOR ALCOHOLISM SUSCEPTIBILITY
    Tatiana Foroud; Fiscal Year: 2003
    ..These studies will result in more sophisticated genetic analyses of alcoholism related data, as well as the development of optimum sampling designs for more efficient gene identification. ..
  49. Advanced NeuroImaging for Acute Stroke Treatment
    Max Wintermark; Fiscal Year: 2007
    ..Invited junior scientists, for whom funding is requested, were selected based on merit. [unreadable] [unreadable] [unreadable]..
  50. Neurologic Basis of the Inhibitory Deficits in ADHD
    STEWART MOSTOFSKY; Fiscal Year: 2008
    ..abstract_text> ..
  51. Neurology of Deficient Response Inhibition in ADHD
    STEWART MOSTOFSKY; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  52. The molecular bases of inherited urea cycle disorders and ureagenesis regulation
    Mendel Tuchman; Fiscal Year: 2010
    ....
  53. PROGNOSIS OF CHILDREN WITH A FIRST UNPROVOKED SEIZURE
    Shlomo Shinnar; Fiscal Year: 2002
    ....
  54. Neuropsychological Testing for Lupus and Depression
    Elizabeth Kozora; Fiscal Year: 2002
    ....
  55. Natural History of Muscular & Reflex Changes in Stroke
    MEHDI MIRBAGHERI; Fiscal Year: 2004
    ..The changes in passive and intrinsic stiffness are likely to be highly correlated with severity of spasticity and inversely correlated with recovery of function. ..
  56. International Conference on the Non-Dystrophic Myotonias
    RICHARD BAROHN; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  57. fMRI and Sports-Related Concussion
    Mark Lovell; Fiscal Year: 2005
    ..The results of this study also will help determine which medications or other therapies are most likely to benefit victims of concussion in subsequent therapeutic trials. ..
  58. HIPPOCAMPAL NETWORK STRUCTURE AND FUNCTION IN EPILEPSY
    ROBERT SLOVITER; Fiscal Year: 2006
    ..abstract_text> ..
  59. Plasticity of Language Networks in Childhood Epilepsy
    WILLIAM GAILLARD; Fiscal Year: 2006
    ..Furthermore, patients may be identified and evaluated at the outset of the disease process so that the neuronal response and degree of plasticity may be assessed and monitored. ..
  60. Arachidonic Acid in Alzheimer's Disease Pathogenesis
    RENE SANCHEZ MEJIA; Fiscal Year: 2006
    ..I will test whether inhibition of PLA2 will prevent and reverse AD-like morphological, molecular, and functional alterations in hAPP mice. [unreadable] [unreadable] [unreadable]..
  61. FMRI ANALYSIS OF IMPLICIT MEMORY IN NORMAL AGING
    Debra Fleischman; Fiscal Year: 2004
    ....
  62. Vascular depression and magnetic stimulation therapy
    Robert Robinson; Fiscal Year: 2005
    ..e. more atrophy lower response rate) and cognitive function. ..
  63. Effects of Chemotherapy on Brain Function
    William J Jagust; Fiscal Year: 2010
    ..They are also relevant to the overall mission of the NIH because of the negative impact that cognitive dysfunction has on quality of life. ..
  64. Macrophages, HAART, and HIV dementia in Thailand
    Victor Valcour; Fiscal Year: 2006
    ..Given this unique cohort, we further intend to use proteomics to generate important molecular markers that predict M/M/phi response to HAART and that distinguish HAD in HAART-treated compared to HAART-naive individuals. ..
  65. C-Reactive Protein in Extremely Low Birth Weight Neonates
    Namasivayam Ambalavanan; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  66. Early Randomized Surgical Epilepsy Trial
    Jerome Engel; Fiscal Year: 2007
    ..abstract_text> ..
  67. IMAGE REPRESENTATION IN THE PRIMARY VISUAL CORTEX
    Allan Gottschalk; Fiscal Year: 2002
    ..In addition, this material provides an important quantitative link between biologic and synthetic methods of image representation. ..
  68. Amyloid Imaging in Frontotemporal Dementia and Alzheimer's Disease
    William Jagust; Fiscal Year: 2009
    ..PIB could become a diagnostic tool that is useful in diagnosing AD and FTLD during life. This will be especially important as new treatments for both disorders are developed. ..
  69. Contribution of Spinal Segments to Control of Posture
    Sandra Saavedra; Fiscal Year: 2008
    ..The technique will also enhance the potential for research on development of motor control of the trunk. [unreadable] [unreadable] [unreadable]..
  70. Genetic Polymorphism of a Schizophrenia Endophenotype
    Ikwunga Wonodi; Fiscal Year: 2007
    ..Deciphering the genetic mechanisms of prefrontal dopamine dysfunction in schizophrenia would advance our understanding of the pathophysiology of schizophrenia and may help identify novel treatments. [unreadable] [unreadable] [unreadable]..
  71. Austin 5HT Candidate Gene Discovery with C Elegans
    J Jay Gargus; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  72. EXPANDED NEWBORN SCREENING FOR METABOLIC DISORDERS
    Susan Waisbren; Fiscal Year: 2006
    ..Primary data from parent interviews and the New England Newborn Screening Program, as well as secondary data from published reports and a panel of experts will be used as inputs to the cost-effectiveness model. [unreadable] [unreadable]..
  73. Measurement & Prediction of Everyday Function Dementia
    Sarah Tomaszewski Farias; Fiscal Year: 2007
    ..Measures of disability and preliminary assessment of handicap will also be included to examine the relationship between the different levels functional change set forth in the model. ..
  74. Immune reactivity to synapsin in the neuropathy and ataxia of celiac disease
    Armin Alaedini; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..