neurological diagnostic techniques

Summary

Summary: Methods and procedures for the diagnosis of diseases of the nervous system, central and peripheral, or demonstration of neurologic function or dysfunction.

Top Publications

  1. ncbi Painful sensory neuropathy: prospective evaluation using skin biopsy
    M I Periquet
    Department of Neurology, The Ohio State University, Columbus 43210, USA
    Neurology 53:1641-7. 1999
  2. ncbi Why headache treatment fails
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY10461, USA
    Neurology 60:1064-70. 2003
  3. ncbi The diagnostic workup of patients with neuropathic pain
    Steven H Horowitz
    University of Vermont College of Medicine, Burlington, VT 05405, and Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Med Clin North Am 91:21-30. 2007
  4. ncbi Usefulness and limitations of quantitative sensory testing: clinical and research application in neuropathic pain states
    Per Hansson
    Dept of Neurosurgery, Pain Center, Karolinska University Hospital, 171 76 Stockholm, Sweden
    Pain 129:256-9. 2007
  5. ncbi Quantitative sensory testing: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
    M E Shy
    Department of Neurology and Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, USA
    Neurology 60:898-904. 2003
  6. ncbi Trigeminal small-fibre function assessed with contact heat evoked potentials in humans
    A Truini
    Department of Neurological Sciences, La Sapienza University, Viale Università 30, 00185 Rome, Italy
    Pain 132:102-7. 2007
  7. ncbi The LDIflare: a novel test of C-fiber function demonstrates early neuropathy in type 2 diabetes
    Singhan T M Krishnan
    FRCP, The Ipswich Diabetes Centre, Ipswich Hospital NHS Trust, Heath Road, Ipswich, UK
    Diabetes Care 27:2930-5. 2004
  8. ncbi Wartenberg pendulum test: objective quantification of muscle tone in children with spastic diplegia undergoing selective dorsal rhizotomy
    Eva Nordmark
    Department of Physical Therapy, Institute of Musculoskeletal Disorders, Lund University, Sweden
    Dev Med Child Neurol 44:26-33. 2002
  9. ncbi Distal symmetric polyneuropathy: a definition for clinical research: report of the American Academy of Neurology, the American Association of Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation
    J D England
    Neurology 64:199-207. 2005
  10. pmc Connecting impairment, disability, and handicap in immune mediated polyneuropathies
    I S J Merkies
    Department of Neurology, Daniel den Hoed Cancer Centre, University Hospital Rotterdam Erasmus University, Rotterdam, Netherlands
    J Neurol Neurosurg Psychiatry 74:99-104. 2003

Research Grants

  1. SEMANTIC AND VISUAL COGNITION IN ALZHEIMERS DISEASE
    Martha Farah; Fiscal Year: 2001
  2. Peripheral Nerve Ischemia
    Phillip Low; Fiscal Year: 2004
  3. Poverty and the Brain: A Cognitive Neuroscience Analysis
    Martha Farah; Fiscal Year: 2007
  4. NORMING A DIAGNOSTIC MOTOR SCALE FOR INFANTS
    Suzann Campbell; Fiscal Year: 2002
  5. The utility of rTMS to enhance hand function in stroke
    Gwyn Lewis; Fiscal Year: 2007
  6. MULTICENTER NETWORK OF NEONATAL INTENSIVE CARE UNITS
    T O SHEA; Fiscal Year: 2005
  7. Genetic and Environmental Risk Factors for PSP
    Irene Litvan; Fiscal Year: 2010
  8. DIABETIC AUTONOMIC NEUROPATHY
    Phillip Low; Fiscal Year: 2001
  9. Biomarkers in Aging, MCI and Alzheimer's Disease
    Douglas Galasko; Fiscal Year: 2007
  10. 5-Year Survival Following Injury in Geriatric Patients
    Laura Criddle; Fiscal Year: 2006

Detail Information

Publications194 found, 100 shown here

  1. ncbi Painful sensory neuropathy: prospective evaluation using skin biopsy
    M I Periquet
    Department of Neurology, The Ohio State University, Columbus 43210, USA
    Neurology 53:1641-7. 1999
    ..have a peripheral neuropathy? 2) What is the role of skin biopsy in establishing a diagnosis of neuropathy? 3) What conditions are associated with the neuropathy? and 4) What laboratory studies are useful in this patient population?..
  2. ncbi Why headache treatment fails
    R B Lipton
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY10461, USA
    Neurology 60:1064-70. 2003
    ..Persistence in treating these patients can be very rewarding. The authors provide a checklist intended to facilitate the management of refractory patients...
  3. ncbi The diagnostic workup of patients with neuropathic pain
    Steven H Horowitz
    University of Vermont College of Medicine, Burlington, VT 05405, and Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Med Clin North Am 91:21-30. 2007
    ..Thus, symptom assessment remains indispensable in the evaluation of neuropathic pain, ancillary testing notwithstanding..
  4. ncbi Usefulness and limitations of quantitative sensory testing: clinical and research application in neuropathic pain states
    Per Hansson
    Dept of Neurosurgery, Pain Center, Karolinska University Hospital, 171 76 Stockholm, Sweden
    Pain 129:256-9. 2007
  5. ncbi Quantitative sensory testing: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
    M E Shy
    Department of Neurology and Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, USA
    Neurology 60:898-904. 2003
    ..This assessment evaluates the clinical utility, efficacy, and safety of quantitative sensory testing (QST)...
  6. ncbi Trigeminal small-fibre function assessed with contact heat evoked potentials in humans
    A Truini
    Department of Neurological Sciences, La Sapienza University, Viale Università 30, 00185 Rome, Italy
    Pain 132:102-7. 2007
    ..Contact heat stimulation, as well as laser stimulation, easily yields large-amplitude brain potentials and nociceptive reflexes, both related to the Adelta input. However CHEPs are not suitable for C-fibres potentials recording...
  7. ncbi The LDIflare: a novel test of C-fiber function demonstrates early neuropathy in type 2 diabetes
    Singhan T M Krishnan
    FRCP, The Ipswich Diabetes Centre, Ipswich Hospital NHS Trust, Heath Road, Ipswich, UK
    Diabetes Care 27:2930-5. 2004
    ..The aim of this study was to evaluate a novel method for assessing the axon reflex and to determine its value in detecting neuropathy in type 2 diabetes...
  8. ncbi Wartenberg pendulum test: objective quantification of muscle tone in children with spastic diplegia undergoing selective dorsal rhizotomy
    Eva Nordmark
    Department of Physical Therapy, Institute of Musculoskeletal Disorders, Lund University, Sweden
    Dev Med Child Neurol 44:26-33. 2002
    ..Swing time was the most reliable and sensitive variable; it showed a weak correlation with measurements for gross motor function...
  9. ncbi Distal symmetric polyneuropathy: a definition for clinical research: report of the American Academy of Neurology, the American Association of Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation
    J D England
    Neurology 64:199-207. 2005
    ..The inclusion of this formalized case definition in clinical and epidemiologic research studies will ensure greater consistency of case selection...
  10. pmc Connecting impairment, disability, and handicap in immune mediated polyneuropathies
    I S J Merkies
    Department of Neurology, Daniel den Hoed Cancer Centre, University Hospital Rotterdam Erasmus University, Rotterdam, Netherlands
    J Neurol Neurosurg Psychiatry 74:99-104. 2003
    ..However, the ICIDH has been criticised on the grounds that it only represents a general, non-specific relation between its entities...
  11. ncbi Reliability and diagnostic accuracy of the clinical examination and patient self-report measures for cervical radiculopathy
    Robert S Wainner
    U S Army Baylor Graduate Program in Physical Therapy, Fort Sam, Houston, Texas, USA
    Spine (Phila Pa 1976) 28:52-62. 2003
    ..A blinded, prospective diagnostic test study was conducted...
  12. ncbi NC-stat as a screening tool for carpal tunnel syndrome
    J Thomas Megerian
    J Occup Environ Med 48:755-6; author reply 757-8. 2006
  13. pmc A diagnostic support tool for lumbar spinal stenosis: a self-administered, self-reported history questionnaire
    Shin ichi Konno
    Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima City, Fukushima, Japan
    BMC Musculoskelet Disord 8:102. 2007
    ..The aim of the present study was to use this tool to assess the diagnostic value of the history of the patient for categorization of LSS...
  14. ncbi Effects of prolonged wrist flexion on transmission of sensory information in carpal tunnel syndrome
    Richard F Sesek
    Department of Mechanical Engineering, University of Utah, Salt Lake City, Utah, USA
    J Pain 8:137-51. 2007
    ....
  15. pmc Cognitive assessment for clinicians
    C M Kipps
    MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge CB2 2EF, UK
    J Neurol Neurosurg Psychiatry 76:i22-30. 2005
  16. ncbi Diabetic neuropathy: a review emphasizing diagnostic methods
    Bruce A Perkins
    EN 11 209, TGH, University Health Network, University of Toronto, 200 Elizabeth Street, Toronto, Ontario, Canada M5G 2C4
    Clin Neurophysiol 114:1167-75. 2003
    ..Novel investigative techniques are highly promising, but their usefulness in the clinic setting remains limited at this time. This article presents an overview of diagnostic methods for DSP...
  17. ncbi Segmental study of the median nerve versus comparative tests in the diagnosis of mild carpal tunnel syndrome
    Jau Jiuan Sheu
    Department of Neurology, Taipei Medical University Hospital, 252 Wu Hsing Street, Taipei, Taiwan, ROC
    Clin Neurophysiol 117:1249-55. 2006
    ..The aims of this study were to analyze normative data of nerve conduction studies (NCS) by optimal transformations, and compare the utility of electrodiagnostic tests in detecting mild carpal tunnel syndrome (CTS)...
  18. ncbi [Practical exercises on diagnostic test interpretation]
    A Perez Sempere
    Servicio de Neurologia, Hospital Vega Baja Orihuela, Alicante, Spain
    Neurologia 18:46-52. 2003
    ..The last example explains the use of ROC curves in the diagnosis of demyelinating disease with CSF-IgG index...
  19. ncbi The avian neurologic examination and ancillary neurodiagnostic techniques: a review update
    Tracy L Clippinger
    Department of Veterinary Services, Zoological Society of San Diego San Diego Zoo, 1354 Old Globe Way, San Diego, CA 92101 1635, USA
    Vet Clin North Am Exot Anim Pract 10:803-36, vi. 2007
    ..Once the disease location and pathologic process have been identified, appropriate treatment and prognosis may be provided...
  20. ncbi The neurological examination and lesion localization in the companion rabbit (Oryctolagus cuniculus)
    Karen M Vernau
    Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, USA
    Vet Clin North Am Exot Anim Pract 10:731-58, v. 2007
    ..This article presents the neurological examination of the rabbit, followed by a practical guide to lesion localization in this species...
  21. ncbi [All that neurologist would like to know about sensitivity, specificity and predictive values]
    A Gomez de la Camara
    Unidad de Epidemilogía Clínica, Unidad de Investigación Hospital Doce de Octubre, Insalud Area 11, Madrid, Spain
    Neurologia 18:11-8. 2003
    ..Decision making with the information provided by the test implies to consider the consequences of the false result...
  22. ncbi Optimal distance for segmental nerve conduction studies revisited
    Mark E Landau
    Department of Neurology, Walter Reed Army Medical Center, 6900 Georgia Ave, Washington, DC 20307, USA
    Muscle Nerve 27:367-9. 2003
    ..With advances in electrodiagnostic equipment, NCV can reasonably be calculated at distances less than 10 cm, perhaps as low as 5-6 cm...
  23. ncbi J.-M. Charcot and simulated neurologic disease: attitudes and diagnostic strategies
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Neurology 69:103-9. 2007
    ..Neurologists have long wrestled with the diagnosis of elaborated or feigned disease. Studies have not focused on early techniques utilized to diagnose malingering...
  24. ncbi Monotonicity of nerve tests in diabetes: subclinical nerve dysfunction precedes diagnosis of polyneuropathy
    Peter J Dyck
    Department of Neurology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA
    Diabetes Care 28:2192-200. 2005
    ..The objective of this study was to test whether monotone worsening of nerve function, attributable to diabetes, can be demonstrated before criteria for diabetic sensorimotor polyneuropathy (DSPN) have been met. Which nerve tests are best?..
  25. ncbi Assessment of medical student clinical competencies in the neurology clinic
    Larry E Davis
    Neurology Service, New Mexico VA Health Care System, Albuquerque, NM 87108, USA
    Neurology 68:597-9. 2007
    ..This form improved student clinical competency assessment and enhanced teaching in clinics...
  26. ncbi Apparent weakness of ulnar-innervated muscles in radial palsy
    Menachem Sadeh
    Department of Neurology, Edith Wolfson Medical Center, Holon, Israel
    Neurology 62:1424-5. 2004
    ..This apparent weakness may be due to their unopposed traction on the extensor expansion by the paralyzed extensor digitorum...
  27. ncbi Intraoperative electromyography
    Neil R Holland
    J Clin Neurophysiol 19:444-53. 2002
    ..The author reviews these basic electrophysiologic techniques, how they are applied to specific surgical situations, and their limitations...
  28. ncbi New criteria for early electrodiagnosis of acute inflammatory demyelinating polyneuropathy
    Amer Al-Shekhlee
    Department of Neurology, University Hospitals of Cleveland, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, Ohio 44106 5040, USA
    Muscle Nerve 32:66-72. 2005
    ..9). We conclude that a new criterion with graded certainty is of higher specificity in the majority of patients with early AIDP...
  29. ncbi Clinical and electrodiagnostic testing of carpal tunnel syndrome: a narrative review
    Joy C MacDermid
    School of Rehabilitation Sciences, McMaster University, Hamilton, Ontario, Canada
    J Orthop Sports Phys Ther 34:565-88. 2004
    ..The pathophysiologic changes occurring with different stages of nerve compression must be considered when interpreting diagnostic test results and predicting response to physical therapy management...
  30. ncbi NC-stat as a screening tool for carpal tunnel syndrome in industrial workers
    Richard T Katz
    Neurology Physical Medicine and Rehabilitation, Washington University School of Medicine, St Louis, Missouri, USA
    J Occup Environ Med 48:414-8. 2006
    ..The initial purpose of this study was to establish a normal data set for median nerve studies in industrial workers using NC-stat technology...
  31. ncbi [Rapid test performance characteristics evaluation]
    A Martinot
    Service de Pediatrie Generale, urgences et maladies infectieuses, Clinique de pédiatrie et pôle de l urgence, CHRU de Lille, Hopital Jeanne de Flandre, avenue E Avinee, 59037 Lille Cedex, France
    Arch Pediatr 14:524-6. 2007
  32. ncbi Comparison of motor conduction techniques in the diagnosis of carpal tunnel syndrome
    Ming Hong Chang
    Section of Neurology, Taichung Veterans General Hospital, No 160 Chung Kang Road, Section 3, Taichung, Taiwan 40705
    Neurology 58:1603-7. 2002
    ..To compare the sensitivities of motor wrist-to-palm (W-P) conduction velocity and two median-ulnar motor latency differences with that of sensory W-P conduction velocity in the diagnosis of carpal tunnel syndrome (CTS)...
  33. ncbi The use of diagnostic ultrasound in carpal tunnel syndrome
    Ethan R Wiesler
    Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Hand Surg Am 31:726-32. 2006
    ....
  34. ncbi A new motor performance test in a prospective study on children with suspected myopathy
    Willeke A van den Beld
    Interdisciplinary Child Neurology Centre and Department of Rehabilitation Medicine, University Medical Centre Nijmegen St Radboud, Nijmegen, The Netherlands
    Dev Med Child Neurol 48:739-43. 2006
    ..This non-invasive and child-friendly motor performance test can improve diagnostic procedure and, therefore, spare more children from unnecessary muscle biopsy...
  35. ncbi Alzheimer's disease and frontal variant of frontotemporal dementia-- a very brief battery for cognitive and behavioural distinction
    Roberta Perri
    Fondazione IRCCS Santa Lucia, Via Ardeatina, 306, 00179 Roma, Italy
    J Neurol 252:1238-44. 2005
    ..The present results emphasise the importance of rating both cognitive and behavioural clinical features of the two syndromes as objectively as possible to improve differential diagnostic accuracy...
  36. ncbi Emerging neurotechnologies for lie-detection: promises and perils
    Paul Root Wolpe
    University of Pennsylvania, USA
    Am J Bioeth 5:39-49. 2005
    ..Premature application of these technologies outside of research settings should be resisted, and the social conversation about the appropriate parameters of its civil, forensic, and security use should begin...
  37. ncbi The role of neuroimaging in dementia
    C DeCarli
    Department of Neurology, University of California, Davis, California, USA
    Clin Geriatr Med 17:255-79. 2001
    ..This article reviews the basic concepts of brain imaging and clinical application. It concludes with a brief discussion of future directions in neuroimaging for the diagnosis and longitudinal follow-up of Alzheimer's disease...
  38. ncbi The sensitivity and specificity of functional capacity evaluations in determining maximal effort: a randomized trial
    Mark Lemstra
    Applied Research Psychiatry, College of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Canada
    Spine (Phila Pa 1976) 29:953-9. 2004
    ..Randomized trial...
  39. ncbi Quantitative assessment of diabetic peripheral neuropathy with use of the clanging tuning fork test
    David S Oyer
    Department of Clinical Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Endocr Pract 13:5-10. 2007
    ..07 (10 g) Semmes-Weinstein monofilament test...
  40. ncbi Reliability and validity of the Canadian Neurological Scale in retrospective assessment of initial stroke severity
    Knut Stavem
    Department of Medicine, Akershus University Hospital, Nordbyhagen, Norway
    Cerebrovasc Dis 16:286-91. 2003
    ..We wanted to assess the reliability and validity of the retrospective use of the Canadian Neurological Scale (CNS)...
  41. ncbi Evaluation of a clinical screening tool for HIV-associated sensory neuropathies
    Catherine L Cherry
    Burnet Institute, Melbourne, Australia
    Neurology 65:1778-81. 2005
    ..To evaluate the performance characteristics of a brief clinical neuropathy screening tool for use in sensory neuropathies complicating HIV infection...
  42. ncbi Ultrasound imaging in the diagnosis of carpal tunnel syndrome and its relevance to clinical evaluation
    Nurdan Kotevoglu
    Department of Physical Therapy and Rehabilitation, Sisli Etfal Teaching Hospital, Istanbul, Turkey
    Joint Bone Spine 72:142-5. 2005
    ..In this study we looked for the diagnostic role of ultrasound in the carpal tunnel syndrome and its correlation with some clinical tests as Phalen and Tinnel sign...
  43. ncbi Lack of utility of Semmes-Weinstein monofilament testing in suspected carpal tunnel syndrome
    Keith J Pagel
    Rehabilitation Medicine Service, Department of Veterans Affairs Medical Center, Portland, Oregon 97207, USA
    Am J Phys Med Rehabil 81:597-600. 2002
    ..To investigate the value of Semmes-Weinstein monofilament (SWM) testing in patients with electrodiagnostically confirmed carpal tunnel syndrome in a group of patients with symptoms compatible with carpal tunnel syndrome...
  44. ncbi The role of neuro-electrophysiological diagnostic tests in clinical medicine
    S O Mbuya
    Department of Clinical Pharmacology, College of Health Sciences, University of Nairobi, Kenya
    East Afr Med J 83:52-60. 2006
    ..To summarise and discuss the role of neuro-electrophysiological diagnostic tests in clinical medicine...
  45. ncbi [The role of electrodiagnostic studies in the diagnosis of hypotonia in infancy]
    F Renault
    Unité de Neurophysiologie Clinique, Hopital d Enfants Armand Trousseau, Paris 12, France
    Rev Med Liege 59:190-7. 2004
    ..Benign congenital hypotonia is a quite rare condition that is diagnosed retrospectively, when hypotonia is strictly isolated and recovers completely before 2 years of age...
  46. ncbi Talking the talk on walking the walk: a 12-item generic walking scale suitable for neurological conditions?
    A Holland
    Neurorehabilitation Group, Institute of Neurology, Queen Square, London, WC1N 3BG, UK
    J Neurol 253:1594-602. 2006
    ....
  47. ncbi Isolated use of vibration perception thresholds and semmes-weinstein monofilament in diagnosing diabetic polyneuropathy: "the North Catalonia diabetes study"
    Jeroni Jurado
    Primary Care, Catalan Health Institute, Olot Girona, Spain
    Nurs Clin North Am 42:59-66. 2007
    ..MF, by MDNS criteria, was more sensitive and specific, and showed more accurate positive and negative predictive values. The predicted probability of DPN diagnosis was higher with a tuning fork evaluation...
  48. ncbi Diagnostic techniques and clinicopathologic findings in ruminant neurologic disease
    Philip R Scott
    Division of Veterinary Clinical Studies, Royal Dick School of Veterinary Studies, University of Edinburgh, Scotland, United Kingdom
    Vet Clin North Am Food Anim Pract 20:215-30, v. 2004
    ..Familiarity with the technique aids high extradural injection of lidocaine or xylazine, which has many applications in farm practice. There are few indications for cisternal CSF collection in food animals...
  49. ncbi The neurologic examination and neurodiagnostic techniques for reptiles
    Christopher L Mariani
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606 1428, USA
    Vet Clin North Am Exot Anim Pract 10:855-91, vii. 2007
    ..Physical examination and history are discussed, as well as invasive and noninvasive testing modalities...
  50. ncbi Magnetic resonance spectroscopy in pediatric neurology
    Sheffali Gulati
    Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India
    Indian J Pediatr 70:317-25. 2003
    ..Few representative case studies among different disease groups have also been detailed...
  51. ncbi Principles of neurological imaging of exotic animal species
    Marguerite F Knipe
    Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California Davis, 2122 Tupper Hall, Davis, CA 95616, USA
    Vet Clin North Am Exot Anim Pract 10:893-907, vii. 2007
    ..This article discusses the basic imaging principles of radiology, myelography, CT, and MRI of the nervous system of companion exotic animals to aid exotic animal clinicians in selecting imaging modalities and interpreting the results...
  52. ncbi Clinical neurology of ferrets
    Orlando Diaz-Figueroa
    Lake Howell Animal Clinic, 856 Lake Howell Rd, Maitland, FL 32751, USA
    Vet Clin North Am Exot Anim Pract 10:759-73, v-vi. 2007
    ..Recent advances in ferret medicine and veterinary neurology offer new capabilities to investigate and treat neurological disease in ferrets...
  53. ncbi The role of neuroimaging studies in normal-pressure glaucoma
    Christopher A Girkin
    J Glaucoma 11:277-8. 2002
  54. ncbi Identifying children with neurological impairment and disability in resource-poor countries
    V Mung'ala-Odera
    Center for Geographic Medicine Coast, Kenya Medical Research Institute, P O 428 Kilifi, Kenya
    Child Care Health Dev 33:249-56. 2007
    ..In RPCs, the most appropriate method should be inexpensive, simple, rapid and accurate. This article reviews methods used to identify children with NI and disability in RPCs, evaluating their effectiveness and suitability...
  55. pmc Imaging or imagining? A neuroethics challenge informed by genetics
    Judy Illes
    Stanford University, USA
    Am J Bioeth 5:5-18. 2005
    ..Indeed, ethical interpretation of such findings will necessitate not only traditional bioethical input but also a wider perspective on the construction of scientific knowledge...
  56. ncbi [What happens in the brain of my patients? Neuroimaging and neurogenetics as ethical challenges in medicine]
    M Synofzik
    Abteilung für Kognitive Neurologie, Hertie Institut für Klinische Hirnforschung, Tubingen
    Dtsch Med Wochenschr 132:2646-9. 2007
    ....
  57. ncbi [Ethical issues of diagnostic tests in neurology]
    P Guerrero
    Seccion de Neurologia, Hospital General de Segovia, Segovia
    Neurologia 18:19-28. 2003
    ..Diagnostic necessities and knowledge of efficiency of tests must be defined in order to make beneficent and just diagnostic decisions...
  58. ncbi Neurology 2004
    Robert C Griggs
    Neurology 62:4-5. 2004
  59. ncbi F wave study in amyotrophic lateral sclerosis: assessment of balance between upper and lower motor neuron involvement
    Andreas A Argyriou
    EMG Laboratory, Department of Neurology, The University of Patras Medical School, P O Box 1045, 26504 Rion Patras, Greece
    Clin Neurophysiol 117:1260-5. 2006
    ..Furthermore, an interpretation of these F wave abnormalities in the context of upper (UMN) and lower motor neuron (LMN) dysfunction was attempted...
  60. ncbi [Electrodiagnosis of neuropathy and myopathy in rheumatoid arthritis]
    Kimitaka Hase
    Department of Rehabilitation Medicine, Keio University School of Medicine
    Nihon Rinsho 63:379-85. 2005
  61. ncbi Nerve conduction and excitability studies in peripheral nerve disorders
    Christian Krarup
    Department of Clinical Neurophysiology, Rigshospitalet and the Institute of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark
    Curr Opin Neurol 22:460-6. 2009
    ..Nerve excitability studies are relatively novel but are acquiring an increasingly important role in the study of peripheral nerves...
  62. ncbi Can we scan for truth in a society of liars?
    Tom Buller
    University of Alaska Anchorage, USA
    Am J Bioeth 5:58-60; discussion W5. 2005
  63. ncbi The medial antebrachial cutaneous nerve: antidromic and orthodromic conduction studies
    Paul Seror
    Laboratory of Electromyography, 146 Avenue Ledru Rollin, 75011 Paris, France
    Muscle Nerve 26:421-3. 2002
    ..With both techniques, no SAP amplitude was lower than 6 microV. The lower limits of normal of the interside amplitude ratio were 1.66 when both techniques were used and 2.0 when only one was used...
  64. ncbi Validation of a novel screening device (NeuroQuick) for quantitative assessment of small nerve fiber dysfunction as an early feature of diabetic polyneuropathy
    Dan Ziegler
    Deutsche Diabetes Klinik, Deutsches Diabetes Zentrum, Leibniz Zentrum an der Heinrich Heine Universität, Auf m Hennekamp 65, 40225 Dusseldorf, Germany
    Diabetes Care 28:1169-74. 2005
    ..To validate a handheld screening device (NeuroQuick) for an early detection of diabetic distal symmetric polyneuropathy (DSP) by quantitative testing of cold sensation based on the wind chill factor (NeuroQuick threshold [NQT])...
  65. ncbi Clinical electromyography and electrodiagnosis course at Keio University Hospital--a 7-year experience
    Meigen Liu
    Department of Rehabilitation Medicine, Keio University School of Medicine, Tokyo, Japan
    Keio J Med 54:193-6. 2005
    ..A follow-up system for the course graduates is planned to support their EMG-EDX practice...
  66. ncbi Measuring the impact of MS on walking ability: the 12-Item MS Walking Scale (MSWS-12)
    J C Hobart
    Institute of Neurology, University College London, UK
    Neurology 60:31-6. 2003
    ..To develop a patient-based measure of walking ability in MS...
  67. ncbi The acute phase reactant, fibrinogen, as a guide to plasma exchange therapy for acute Guillain-Barré syndrome
    Rashmi Sanjay
    Department of Medicine, Hematology and Transfusion Medicine Section, Caritas St Elizabeth s Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02135, USA
    J Clin Apher 21:105-10. 2006
    ..Therapeutic plasma exchange need not be extended when plasma fibrinogen remains > or =30% below its level at presentation by the time of the final planned plasma exchange procedure...
  68. ncbi The effect of footwear and sports-surface on dynamic neurological screening for sport-related concussion
    Anthony G Schneiders
    Centre for Physiotherapy Research, University of Otago, New Zealand
    J Sci Med Sport 13:382-6. 2010
    ..These findings suggest that clinicians should standardise footwear and the testing surface at baseline in order to accurately assess motor performance tests when SRC is suspected...
  69. ncbi [Neurological recovery after cervical cord decompression for canal stenosis myelopathy]
    H Pascal-Moussellard
    Service d Orthopedie, CHU Pitie Salpetriere, 47, Boulevard de l Hopital, 75651 Paris Cedex 13
    Rev Chir Orthop Reparatrice Appar Mot 91:607-14. 2005
    ..Results of surgical decompression are generally good but the pattern of neurological recovery has not been studied. We followed a cohort of patients who underwent cervical cord decompression to study the course of neurological recovery...
  70. ncbi Tactile temporal thresholds detect relapse-related changes in multiple sclerosis: a preliminary study
    L N Brown
    Department of Clinical Neurosciences, University of Calgary, Alberta, Canada
    Mult Scler 11:725-7. 2005
    ..Thus, tactile temporal thresholds may be a useful outcome measure in MS. Our objective was to assess whether tactile temporal thresholds reflect change during a MS relapse...
  71. ncbi Endogenous fluorescence imaging of somatosensory cortical activities after discrimination learning in rats
    Katsuei Shibuki
    Department of Neurophysiology, Brain Research Institute, Niigata University, 1 Asahi machi, Niigata 951 8585, Japan
    Neuroimage 30:735-44. 2006
    ..The present results indicate the usefulness of flavoprotein fluorescence imaging for investigating somatosensory cortical plasticity after learning...
  72. ncbi EFNS guidelines on the use of skin biopsy in the diagnosis of peripheral neuropathy
    G Lauria
    Immunology and Muscular Pathology Unit, Department of Clinical Neurosciences, National Neurological Institute Carlo Besta, Milan, Italy
    Eur J Neurol 12:747-58. 2005
    ..Training in an established cutaneous nerve laboratory is recommended before using skin biopsy as a diagnostic tool in peripheral neuropathies. Quality control at all levels is mandatory...
  73. ncbi Tripod sign
    J C Suvarna
    Department of Pediatrics, Seth GS Medical College and KEM Hospital, Parel, Mumbai, India
    J Postgrad Med 55:211-3. 2009
    ..Since elicitation of the sign requires voluntary sitting up, it is of limited use in patients with marked altered sensorium and young infants...
  74. ncbi Prevalence of hyperesthesia detected by current perception threshold test in subjects with glucose metabolic impairments in a community
    Kiyoshi Takekuma
    Department of Public Health, Nagoya City University Medical School, Nagoya
    Intern Med 41:1124-9. 2002
    ....
  75. pmc Autonomic nervous system testing may not distinguish multiple system atrophy from Parkinson's disease
    D E Riley
    Department of Neurology, University Hospitals of Cleveland and Case Western Reserve University School of Medicine, 1100 Euclid Avenue, Cleveland, OH 44106, USA
    J Neurol Neurosurg Psychiatry 74:56-60. 2003
    ....
  76. ncbi [Assessment of dysarthria and dysphagia in ALS patients]
    D Robert
    Fédération ORL, CHU La Timone, 264, rue Saint Pierre, 13385 Marseille Cedex 5
    Rev Neurol (Paris) 162:445-53. 2006
    ....
  77. ncbi The scale for contraversive pushing: A reliability and validity study
    Marco Baccini
    Department of Geriatric Rehabilitation, Florence, Italy
    Neurorehabil Neural Repair 20:468-72. 2006
    ..Pushing toward the hemiplegic side can interfere with mobility training after stroke. This study estimated the internal consistency, interrater reliability, and validity of the Scale for Contraversive Pushing (SCP)...
  78. ncbi Optical induction of synaptic plasticity using a light-sensitive channel
    Yan Ping Zhang
    Friedrich Miescher Institute, Novartis Research Foundation, Maulbeerstr 66, WRO 1066 4 04, CH 4058 Basel, Switzerland
    Nat Methods 4:139-41. 2007
    ..Pairing of light stimulation with postsynaptic depolarization induced long-term potentiation, making this technique ideal for genetic and pharmacological dissection of synaptic plasticity...
  79. ncbi Ethical issues in neuroscience
    Thomas Fuchs
    Psychiatric Department, University of Heidelberg, Heidelberg, Germany
    Curr Opin Psychiatry 19:600-7. 2006
    ..The study gives an overview of ethical questions raised by the progress of neuroscience in identifying and intervening in neural correlates of the mind...
  80. pmc Functional symptoms and signs in neurology: assessment and diagnosis
    J Stone
    Department of Clinical Neurosciences, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    J Neurol Neurosurg Psychiatry 76:i2-12. 2005
  81. ncbi Motor unit number estimation in human neurological diseases and animal models
    J M Shefner
    Department of Neurology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA
    Clin Neurophysiol 112:955-64. 2001
    ..Despite the lack of a perfect method for performing MUNE, it has great clinical value in the assessment of progressive motor axon loss. Further refinements in the method will likely increase its utility in the future...
  82. ncbi Update on concussion: here's what the experts say
    Shawn M Ferullo
    Department of Family Medicine, Boston Medical Center, Boston, MA, USA
    J Fam Pract 59:428-33. 2010
    ..Recommend up-to-date protective equipment for athletes. Recent improvements, especially in football, have been shown to help decrease the incidence of concussion...
  83. ncbi [The methodology for assessment of the alpha-adrenergic sensitivity by the results of clopheline instillation into conjunctival sac in healthy subjects]
    Iu S Kokarev
    Fiziol Cheloveka 28:99-107. 2002
  84. ncbi Can cerebrospinal fluid uric acid levels differentiate intraventricular hemorrhage from traumatic tap?
    Didem Aliefendioglu
    Neonatology Unit, Department of Pediatrics, Kirikkale University Faculty of Medicine, Kirikkale, Turkey
    Biol Neonate 90:268-72. 2006
    ..To measure blood and cerebrospinal fluid (CSF) uric acid (UA) levels of neonates with intraventricular hemorrhage (IVH), and to examine whether or not UA can be used to differentiate traumatic tap from IVH...
  85. ncbi Communication neuroscience as a tool for health psychologists
    Emily B Falk
    Department of Communication Studies, Institute for Social Research, Research Center for Group Dynamics, University of Michigan, Ann Arbor, MI 48016 1248, USA
    Health Psychol 29:355-7. 2010
    ..As such, this study illustrates one benefit of combining the tools of neuroscience with more familiar methods in health psychology...
  86. ncbi Stroke-unit care for patients with acute stroke
    Simona Sacco
    Lancet 369:1255; author reply 1255-6. 2007
  87. ncbi Shortening the NIH Stroke scale for use in the prehospital setting
    David L Tirschwell
    Department of Neurology, Harborview Medical Center, University of Washington School of Medicine, Seattle
    Stroke 33:2801-6. 2002
    ..The goal of this study was to identify a subset of the 15 items in the National Institutes of Health Stroke Scale (NIHSS-15) that measures stroke severity and predicts outcomes...
  88. ncbi Optimisation of a post-processing method to remove the pulse artifact from EEG data recorded during fMRI: an application to P300 recordings during e-fMRI
    H Otzenberger
    UMR 7004 Laboratoire de Neuroimagerie in vivo, Universite Louis Pasteur, Centre National de Recherche Scientifique, IFR 37 de Neurosciences, 4 rue Kirschleger, 67085 Strasbourg Cedex, France
    Neurosci Res 57:230-9. 2007
    ..3-9.09 microV) in centro-parietal and prefrontal areas. The improvement of the processing of EEG data acquired simultaneously with fMRI data provides a new tool and casts perspectives to study the functional organisation of the brain...
  89. ncbi Histological validation of ultrasound-guided neurography in early nerve regeneration
    Johan W van Neck
    Department of Plastic and Reconstructive Surgery, Room Ee15 91, Erasmus MC, University Medical Center, P O Box 2040, Rotterdam 3000, The Netherlands
    Muscle Nerve 40:967-75. 2009
    ..Our results suggest that, following a similar validation study in humans, ultrasound-guided near-nerve neurography may be clinically useful when early evaluation of nerve activity is needed...
  90. ncbi [Congenital myasthenic syndromes: phenotypic expression and pathophysiological characterisation]
    F Andreux
    INSERM 582 et Institut de Myologie, Hopital de la Pitie Salpetriere
    Rev Neurol (Paris) 160:163-76. 2004
    ..Specific therapies for slow channel CMS are quinidine and fluoxetine that normalize the prolonged opening episodes. Clinical benefits derived from the full characterisation of each case include genetic counselling and specific therapy...
  91. ncbi Minimally obtrusive wearable device for continuous interactive cognitive and neurological assessment
    Antoni Ivorra
    Department of Bioengineering, University of California at Berkeley, CA 94720, USA
    Physiol Meas 29:543-54. 2008
    ..The ability to assess cognitive capabilities of individuals continuously during everyday activities could have far-reaching implications for diagnostics and treatment of many different neurological conditions...
  92. ncbi Learning disabilities: definitions, epidemiology, diagnosis, and intervention strategies
    Lieven Lagae
    Department of Pediatric Neurology, University of Leuven Medical School, University Hospitals KULeuven, Herestraat 49, 3000 Leuven, Belgium
    Pediatr Clin North Am 55:1259-68, vii. 2008
    ..The role of the medical professional is important to guide parents in the diagnostic and therapeutic process...
  93. ncbi [Thrombolysis of acute ischemic cerebral vascular accident: roles of the physician and the peripheral hospital]
    Philippe Meyer
    Departement de Medecine, CHUV
    Rev Med Suisse Romande 123:205-10. 2003
    ....
  94. ncbi [Diagnostic reasoning in neurology. An analysis of the more frequent errors]
    J Diaz Guzman
    Servicio de Neurologia, Hospital Universitario Doce de Octubre, Madrid, Spain
    Neurologia 18:3-10. 2003
    ....
  95. ncbi Different odor tests contribute differently to the evaluation of olfactory loss
    Jorn Lotsch
    Pharmazentrum frankfurt ZAFES, Institute of Clinical Pharmacology, Johann Wolfgang Goethe University, Theodor Stern Kai 7, Frankfurt am Main, Germany
    Chem Senses 33:17-21. 2008
    ..In conclusion, combined testing of several components of olfaction, especially including assessment of thresholds, provides the most significant approach to the diagnosis of smell loss...
  96. ncbi Newborn neurologic examination
    Michele Yang
    Children s Hospital of Pittsburgh, PA 15213 2524, USA
    Neurology 62:E15-7. 2004
  97. doi Soul-making in neuroimaging?
    Kevin Chien Chang Wu
    National Taiwan University College of Medicine, 2F Medical Humanity Building, Taipei, Taiwan
    Am J Bioeth 8:21-2. 2008
  98. ncbi [Neuropathy diagnosis strategy]
    Joana Guimarães
    Serviços de Neurologia e de Neurofisiolgia, Hospital de Sao Joao, Porto
    Acta Med Port 21:83-8. 2008
    ..The clinical investigation and electrophysiologic study are fundamental in the investigation study of a neuropathy. The authors present a schematic revision work of the principals aspects of neuropathy clinical and study...
  99. ncbi Intracerebral hemorrhage: effects of aging on brain edema and neurological deficits
    Ye Gong
    Department of Neurosurgery, University of Michigan, Ann Arbor, MI 48109 0532, USA
    Stroke 35:2571-5. 2004
    ..Age is an important factor in other forms of brain injury, affecting microglia and astrocyte reactions and plasticity. Therefore, the present study investigated the effects of aging on brain injury after ICH...
  100. ncbi Tourette's syndrome
    Christopher Kenney
    Department of Neurology, Baylor College of Medicine, Houston, Texas 77030, USA
    Am Fam Physician 77:651-8. 2008
    ..Appropriate diagnosis and treatment can substantially improve quality of life and psychosocial functioning in affected children...
  101. ncbi Change in perfusion in acute nondominant hemisphere stroke may be better estimated by tests of hemispatial neglect than by the National Institutes of Health Stroke Scale
    Argye E Hillis
    Department of Neurology, Johns Hopkins University School of Medicine, Meyer 5 185, 600 N Wolfe St, Baltimore, MD 21287, USA
    Stroke 34:2392-6. 2003
    ..We conducted 2 studies to determine whether tests of hemispatial neglect provide a better measure of hypoperfusion and reperfusion than NIHSS in nondominant hemisphere stroke...

Research Grants32

  1. SEMANTIC AND VISUAL COGNITION IN ALZHEIMERS DISEASE
    Martha Farah; Fiscal Year: 2001
    ..In addition, new predictions of the computational hypotheses have been derived and will form the basis of further empirical tests with human subjects. ..
  2. Peripheral Nerve Ischemia
    Phillip Low; Fiscal Year: 2004
    ..We will then define the therapeutic windows and evaluate the mechanisms of production of hypothermic and antioxidant neuroprotection (Specific aim number 2) from reperfusion injury. ..
  3. Poverty and the Brain: A Cognitive Neuroscience Analysis
    Martha Farah; Fiscal Year: 2007
    ..Neurocognitive systems mediating resilience and successful adolescence will also be sought. ..
  4. NORMING A DIAGNOSTIC MOTOR SCALE FOR INFANTS
    Suzann Campbell; Fiscal Year: 2002
    ..Following completion of this project, the TIMP will be available for use by therapists to diagnosis motor developmental delay in infants from 34 weeks PCA to 4 months past term. ..
  5. The utility of rTMS to enhance hand function in stroke
    Gwyn Lewis; Fiscal Year: 2007
    ..This will be applicable to a large population of US adults with deficits in hand function resulting from stroke. [unreadable] [unreadable] [unreadable]..
  6. MULTICENTER NETWORK OF NEONATAL INTENSIVE CARE UNITS
    T O SHEA; Fiscal Year: 2005
    ..abstract_text> ..
  7. Genetic and Environmental Risk Factors for PSP
    Irene Litvan; Fiscal Year: 2010
    ..The use of the NINDS cell repository for genetic banking will also allow DNA sample sharing with other investigators. ..
  8. DIABETIC AUTONOMIC NEUROPATHY
    Phillip Low; Fiscal Year: 2001
    ..abstract_text> ..
  9. Biomarkers in Aging, MCI and Alzheimer's Disease
    Douglas Galasko; Fiscal Year: 2007
    ..Banked CSF and plasma will be available for further research into novel biomarkers, including broad-based proteomic studies. ..
  10. 5-Year Survival Following Injury in Geriatric Patients
    Laura Criddle; Fiscal Year: 2006
    ..Contribution: This foundational study will provide basic information about the survival patterns of injured elders as a basis for the development of interventions to improve geriatric survival. [unreadable] [unreadable] [unreadable]..
  11. Phase II Therapeutic Trial of Mexiletine
    Richard J Barohn; Fiscal Year: 2010
    ..These secondary measures will be quantified by lndividual Neuromuscular Quality of Life (INQOL), SF-36 (adults), SF-10 (children), grip myotonia, physical exam, and electrophysiological testing, respectively. ..
  12. RUPP-PI Program at Yale University
    Lawrence Scahill; Fiscal Year: 2006
    ..Furthermore, this five-site network has established reliability on several measures that are relevant to the conduct of clinical trials in children with PDD. ..
  13. Bilateral activation in upper-limb stroke rehabilitation
    Gwyn Lewis; Fiscal Year: 2006
    ....
  14. AGE RELATED NEURODEGENERATIVE DISEASES IN MICRONESIA
    Douglas Galasko; Fiscal Year: 2006
    ..Subproject by Lee: 'PHF-tau in neurodegenerative diseases of Guam' will assess oxidative markers related to brain lesions in ALS, PDC and dementia. ..
  15. Behavior Therapy for Adults with Tourette Syndrome
    Lawrence Scahill; Fiscal Year: 2009
    ..The Informatics group at Yale University will provide data management services. ..
  16. Second International Brainstorming Meeting on Parkinson Disease: Nosology
    Irene Litvan; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  17. AMPHETAMINE ENHANCED STROKE RECOVERY--BURKE SRCI GROUP
    Larry Goldstein; Fiscal Year: 2002
    ..However the treatment duration will be increased to a total of 10 sessions. ..
  18. Data Communication with Implantable Micro Devices
    Mingui Sun; Fiscal Year: 2002
    ..We will implant this device within the brain of laboratory dogs and evaluate its performance. ..
  19. NMR STUDIES OF THE MECHANISMS OF ACTION OF TRP REPRESSOR
    Oleg Jardetzky; Fiscal Year: 2002
    ..Correlation of the findings should allow an understanding of the signaling code and the design of the regulatory apparatus. ..
  20. Transcranial Magnetic Stimulation and Neuromodulation
    Jau Shin Lou; Fiscal Year: 2003
    ..The results will provide us with vital information that will allow us to further develop rTMS as a noninvasive therapeutic modality for PD. ..
  21. Use of Albuterol in Spinal Cord Injury
    Richard Zeman; Fiscal Year: 2002
    ..PROPOSED COMMERCIAL APPLICATION: Use of beta 2-agonists like albuterol alone or together with x-irradiation maybe useful therapies for spinal cord injuries. ..
  22. Mechanisms of Spinal Cord Injury
    Richard Zeman; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  23. DIABETIC NEUROPATHY STUDY
    PETER DYCK; Fiscal Year: 2008
    ..abstract_text> ..
  24. Use of Tempol for Spinal Cord Injury
    Richard Zeman; Fiscal Year: 2004
    ..Optimization of tempol treatment may lead to a therapeutic modality for SCI. ..
  25. 11th International Myasthenia Gravis Meeting
    RICHARD BAROHN; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  26. Normal Impulsivity: A Cognitive Neuroscience Analysis
    Martha Farah; Fiscal Year: 2005
    ..abstract_text> ..
  27. International Conference on the Non-Dystrophic Myotonias
    RICHARD BAROHN; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  28. Use of Clenbuterol for Enhancement of Stem Cell Therapy
    Richard Zeman; Fiscal Year: 2002
    ..The method will be patented, licensed and marketed as a new therapy. ..
  29. MIDCAREER INVESTIGATOR AWARD IN CEREBROVASCULAR RESEARCH
    Larry Goldstein; Fiscal Year: 2004
    ....
  30. Online MRI Positioning and Real-Time Motion Correction
    Andre van der Kouwe; Fiscal Year: 2004
    ..The technology will be evaluated in a group of healthy volunteers. ..
  31. Multiple Factors Affecting Placebo Response in PD
    Christopher Goetz; Fiscal Year: 2004
    ..Defining these determinant influences will help enhance placebo responses in clinical practice and control them in clinical trials. ..
  32. Anger Control Training for Youth with Tourette Syndrome
    Larry Scahill; Fiscal Year: 2005
    ..This design will permit demonstration of a clinically relevant effect size for anger control training in adolescents with TS. ..