reproductive history

Summary

Summary: An important aggregate factor in epidemiological studies of women's health. The concept usually includes the number and timing of pregnancies and their outcomes, the incidence of breast feeding, and may include age of menarche and menopause, regularity of menstruation, fertility, gynecological or obstetric problems, or contraceptive usage.

Top Publications

  1. pmc Reproductive history and oral contraceptive use in relation to risk of triple-negative breast cancer
    Amanda I Phipps
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Natl Cancer Inst 103:470-7. 2011
  2. ncbi Normal serum anti-Müllerian hormone levels in the general female population and the relationship with reproductive history
    Antonio La Marca
    Mother Infant Department, Institute of Obstetrics and Gynecology, University of Modena and Reggio Emilia, 41100 Modena, Italy
    Eur J Obstet Gynecol Reprod Biol 163:180-4. 2012
  3. pmc Reproductive history and mortality from cardiovascular disease among women textile workers in Shanghai, China
    Lisa G Gallagher
    Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98195, USA
    Int J Epidemiol 40:1510-8. 2011
  4. ncbi Hormonal factors and pancreatic cancer in women
    N Kreiger
    Division of Preventive Oncology, Research Unit, Cancer Care Ontario, Toronto, Ontario, Canada
    Ann Epidemiol 11:563-7. 2001
  5. ncbi The association of reproductive factors and breastfeeding with long term survival from breast cancer
    Mirjam D K Alsaker
    Department of Public Health, Faculty of Medicine, Norwegian University of Science and Technology, 7489, Trondheim, Norway
    Breast Cancer Res Treat 130:175-82. 2011
  6. pmc Reproductive history and breast cancer risk
    Shunzo Kobayashi
    Department of Breast and Endocrine Surgery, Nagoya City West Medical Center, 1 1 1, Hirate cho, Kita ku, Nagoya, 462 8508, Japan
    Breast Cancer 19:302-8. 2012
  7. pmc The contribution of risk factors to the higher incidence of invasive and in situ breast cancers in women with higher levels of education in the European prospective investigation into cancer and nutrition
    Gwenn Menvielle
    National Institute for Public Health and the Environment RIVM, Bilthoven, The Netherlands
    Am J Epidemiol 173:26-37. 2011
  8. pmc Oral contraceptive use and reproductive factors and risk of ovarian cancer in the European Prospective Investigation into Cancer and Nutrition
    K K Tsilidis
    Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Br J Cancer 105:1436-42. 2011
  9. pmc Reproductive factors and breast cancer risk according to joint estrogen and progesterone receptor status: a meta-analysis of epidemiological studies
    Huiyan Ma
    Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue 4407, Los Angeles, CA 90089, USA
    Breast Cancer Res 8:R43. 2006
  10. pmc Reproductive history and risk of colorectal cancer in postmenopausal women
    Alice Zervoudakis
    Department of Oncology, Montefiore Medical Center, Bronx, NY, USA
    J Natl Cancer Inst 103:826-34. 2011

Detail Information

Publications191 found, 100 shown here

  1. pmc Reproductive history and oral contraceptive use in relation to risk of triple-negative breast cancer
    Amanda I Phipps
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Natl Cancer Inst 103:470-7. 2011
    ..Hormonally mediated risk factors may be differentially related to risk of triple-negative and ER+ breast cancers...
  2. ncbi Normal serum anti-Müllerian hormone levels in the general female population and the relationship with reproductive history
    Antonio La Marca
    Mother Infant Department, Institute of Obstetrics and Gynecology, University of Modena and Reggio Emilia, 41100 Modena, Italy
    Eur J Obstet Gynecol Reprod Biol 163:180-4. 2012
    ..In this study we aim to calculate the age-by-age normal values of circulating AMH. In addition, we report on AMH levels in women according to BMI, smoking status and reproductive history.
  3. pmc Reproductive history and mortality from cardiovascular disease among women textile workers in Shanghai, China
    Lisa G Gallagher
    Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98195, USA
    Int J Epidemiol 40:1510-8. 2011
    ..Few studies have examined the possible effects of reproductive factors on cardiovascular disease (CVD) risks in Asian women...
  4. ncbi Hormonal factors and pancreatic cancer in women
    N Kreiger
    Division of Preventive Oncology, Research Unit, Cancer Care Ontario, Toronto, Ontario, Canada
    Ann Epidemiol 11:563-7. 2001
    ..the hypothesis that pancreatic cancer is, at least in part, an estrogen-dependent disease; there is growing epidemiological evidence that aspects of reproductive history and hormonal exposure are associated with risk of this disease.
  5. ncbi The association of reproductive factors and breastfeeding with long term survival from breast cancer
    Mirjam D K Alsaker
    Department of Public Health, Faculty of Medicine, Norwegian University of Science and Technology, 7489, Trondheim, Norway
    Breast Cancer Res Treat 130:175-82. 2011
    ..We also found that overweight and obesity, as measured many years prior to diagnosis, were associated with poorer survival...
  6. pmc Reproductive history and breast cancer risk
    Shunzo Kobayashi
    Department of Breast and Endocrine Surgery, Nagoya City West Medical Center, 1 1 1, Hirate cho, Kita ku, Nagoya, 462 8508, Japan
    Breast Cancer 19:302-8. 2012
    ..In this review, the significance of reproductive history with regard to the risk of breast cancers will be discussed, focusing on the age of first full-term birth ..
  7. pmc The contribution of risk factors to the higher incidence of invasive and in situ breast cancers in women with higher levels of education in the European prospective investigation into cancer and nutrition
    Gwenn Menvielle
    National Institute for Public Health and the Environment RIVM, Bilthoven, The Netherlands
    Am J Epidemiol 173:26-37. 2011
    ..b>Reproductive history (age at first full-term pregnancy and parity), exposure to endogenous and exogenous hormones, height, and ..
  8. pmc Oral contraceptive use and reproductive factors and risk of ovarian cancer in the European Prospective Investigation into Cancer and Nutrition
    K K Tsilidis
    Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Br J Cancer 105:1436-42. 2011
    ..It is well established that parity and use of oral contraceptives reduce the risk of ovarian cancer, but the associations with other reproductive variables are less clear...
  9. pmc Reproductive factors and breast cancer risk according to joint estrogen and progesterone receptor status: a meta-analysis of epidemiological studies
    Huiyan Ma
    Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue 4407, Los Angeles, CA 90089, USA
    Breast Cancer Res 8:R43. 2006
    ..This report presents the first meta-analysis of results from epidemiological studies that have investigated parity, age at first birth, breastfeeding, and age at menarche in relation to ER+PR+ and ER-PR- cancer risk...
  10. pmc Reproductive history and risk of colorectal cancer in postmenopausal women
    Alice Zervoudakis
    Department of Oncology, Montefiore Medical Center, Bronx, NY, USA
    J Natl Cancer Inst 103:826-34. 2011
    ..A surrogate measure of lifetime estrogen exposure is reproductive history. We investigated the relationship between reproductive factors and the risk of colorectal cancer.
  11. ncbi Effect of anovulation factors on pre- and postmenopausal ovarian cancer risk: revisiting the incessant ovulation hypothesis
    Ko Hui Tung
    Cancer Etiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA
    Am J Epidemiol 161:321-9. 2005
    ....
  12. pmc Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study
    Roger L Milne
    Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre CNIO, Madrid, 28029, Spain
    Breast Cancer Res 12:R110. 2010
    ....
  13. ncbi Pancreatic cancer incidence in relation to female reproductive factors: Iowa Women's Health Study
    Anna E Prizment
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota Minneapolis, MN 55455, USA
    JOP 8:16-27. 2007
    ..Motivated by inconsistent literature, we evaluated the association between incident pancreatic cancer and reproductive characteristics...
  14. ncbi Reproductive history and risk of multiple sclerosis
    Nete Munk Nielsen
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark
    Epidemiology 22:546-52. 2011
    It has been suggested that reproductive factors may be involved in the etiology of multiple sclerosis (MS). We studied associations of reproductive history with MS risk in a population-based setting.
  15. ncbi Reproductive history and mortality in late middle age among Norwegian men and women
    Emily Grundy
    Centre for Population Studies, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Epidemiol 167:271-9. 2008
    ..Discrete-time hazard modeling was used to analyze later-life mortality by aspects of reproductive history. A total of 63,312 deaths were observed during 14...
  16. ncbi The determinants of infant mortality in Pakistan
    S Agha
    Population Services International, Washington, DC 20036, USA
    Soc Sci Med 51:199-208. 2000
    ..Health interventions in Pakistan should be designed to reach the most under-served: women and children. Systematic evaluations of health interventions will be necessary to make informed decisions about health investments in the future...
  17. ncbi Parity, reproductive factors, and the risk of pancreatic cancer in women
    Halcyon G Skinner
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 12:433-8. 2003
    ..Additional studies should examine the physiological or hormonal changes underlying pregnancy or childbirth that may explain this finding...
  18. ncbi [Survival of Aedes albopictus: physiological age and reproductive history]
    Zoraida Fernandez
    Instituto Nacional de Higiene Rafael Rangel, Caracas, Venezuela
    Rev Saude Publica 37:285-91. 2003
    To study the longevity of Ae. albopictus populations in rural and urban areas in two different feeding conditions and to assess their physiological age and reproductive history.
  19. pmc Reproductive history and pancreatic cancer incidence and mortality in a cohort of postmenopausal women
    Richard J Stevens
    Department of Primary Health Care, Oxford, OX3 7LF, UK
    Cancer Epidemiol Biomarkers Prev 18:1457-60. 2009
    There is inconsistent evidence about the effect of reproductive history on women's risk of pancreatic cancer...
  20. ncbi Difference in gene expression profile in breast epithelial cells from women with different reproductive history
    Shanchun Guo
    Breast Cancer Research Laboratory, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Int J Oncol 23:933-41. 2003
    ..The results indicate that differentially expressed genes occur during normal human breast lobular differentiation and these changes might persistently modify the genomic signature of the breast epithelia...
  21. pmc Reproductive history in relation to breast cancer risk among Hispanic and non-Hispanic white women
    Carol Sweeney
    Division of Epidemiology, University of Utah, 30 N 1900 E, AC230, Salt Lake City, Utah 841032, USA
    Cancer Causes Control 19:391-401. 2008
    To evaluate reproductive history risk factors in breast cancer among Hispanic (HISP) women in the U.S. southwest, a population with approximately 33% lower breast cancer incidence than non-Hispanic whites (NHW).
  22. ncbi Genetic and environmental predictors, endogenous hormones and growth factors, and risk of estrogen receptor-positive breast cancer in Japanese women
    Nobuyasu Yoshimoto
    Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, Mizuho ku, Nagoya, Japan
    Cancer Sci 102:2065-72. 2011
    ..Further validation studies will clarify appropriate risk groups for preventive therapy...
  23. ncbi Reproductive factors and histologic subtype in relation to mortality after a breast cancer diagnosis
    S Warren Andersen
    University of Wisconsin Carbone Cancer Center, 610 Walnut St, WARF Room 307, Madison, WI 53726, USA
    Breast Cancer Res Treat 130:975-80. 2011
    ..We found increasing parity reduced mortality in ductal and lobular breast cancer. The number of full-term births, rather than age at first birth, has an effect on both breast cancer-specific and overall mortality...
  24. ncbi Maternal reproductive history and the risk of isolated congenital malformations
    A Materna-Kiryluk
    Department of Medical Genetics, Poznan University of Medical Sciences, Poznan, Poland
    Paediatr Perinat Epidemiol 25:135-43. 2011
    We examined the relationship between maternal reproductive history and the newborn's risk of isolated congenital malformations in a large case-control cohort from the Polish Registry of Congenital Malformations...
  25. ncbi Clinical stage of breast cancer by parity, age at birth, and time since birth: a progressive effect of pregnancy hormones?
    Grethe Albrektsen
    Department of Mathematics, Center for International Health, University of Bergen, Bergen, Norway
    Cancer Epidemiol Biomarkers Prev 15:65-9. 2006
    ..Thus, pregnancy hormones may have a progressive effect on breast cancer tumors in addition to a possible promoting effect. A potential effect of prolactin is discussed...
  26. ncbi Reproductive history and adverse pregnancy outcomes in commercial flight crew and air traffic control officers in the United kingdom
    Isabel dos Santos Silva
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, England
    J Occup Environ Med 51:1298-305. 2009
    ..To examine reproductive outcomes among flight crew...
  27. ncbi Oral contraceptive use, hormone replacement therapy, reproductive history and risk of colorectal cancer in women
    Geoffrey C Kabat
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, NY 10461, USA
    Int J Cancer 122:643-6. 2008
    ..However, given the lack of a dose-response relationship and the potential for confounding, studies with more complete assessment of exogenous hormone use throughout the life course are needed to clarify this association...
  28. pmc The baboon model (Papio hamadryas) of fetal loss: maternal weight, age, reproductive history and pregnancy outcome
    Natalia E Schlabritz-Loutsevitch
    Department of Obstetrics and Gynecology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
    J Med Primatol 37:337-45. 2008
    ..Several risk factors are associated with the incidence of human stillbirths. The prevention of stillbirths in women is a pressing clinical problem...
  29. ncbi Risk factors for uterine leiomyoma: a practice-based case-control study. I. African-American heritage, reproductive history, body size, and smoking
    E Faerstein
    Department of Epidemiology, Institute of Social Medicine, State University of Rio de Janeiro, Brazil
    Am J Epidemiol 153:1-10. 2001
    ..These results suggest that development of uterine leiomyoma is associated with increased exposure to ovarian hormones. Possible reasons for the very elevated risk among African-American women need further investigation...
  30. ncbi Review of epidemiological evidence for reproductive and hormonal factors in relation to the risk of epithelial ovarian malignancies
    Tomas Riman
    Department of Obstetrics and Gynecology, Falu Hospital, Falun, Sweden
    Acta Obstet Gynecol Scand 83:783-95. 2004
    ..The aim of this review is to summarize the epidemiological findings on reproductive factors and ovarian cancer risk. These findings are considered in the context of etiologic hypotheses and some new research areas are suggested...
  31. pmc Previous reproductive history and post-natal family planning among HIV-infected women in Ukraine
    J Saxton
    Institute of Child Health, University College, London, UK
    Hum Reprod 25:2366-73. 2010
    ..Our objectives were to describe the reproductive health, condom use and family planning (FP) practices of HIV-positive childbearing Ukrainian women and to identify factors associated with different methods of post-natal contraception...
  32. pmc Menstrual and reproductive factors in relation to ovarian cancer risk
    L Titus Ernstoff
    Department of Community and Family Medicine, Dartmouth Hitchcock Medical Center and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Br J Cancer 84:714-21. 2001
    ..Overall, our findings offer some support to current hypotheses of ovarian pathogenesis, and show aetiologic differences among the tumour subtypes...
  33. pmc Reproductive and hormonal factors in association with ovarian cancer in the Netherlands cohort study
    M G M Braem
    University Medical Center Utrecht, The Netherlands
    Am J Epidemiol 172:1181-9. 2010
    ..Information on reproductive history and exogenous hormone use was obtained through a self-administered questionnaire at baseline in 1986...
  34. pmc Ovarian cancer risk factors in African-American and white women
    Patricia G Moorman
    Duke University Medical Center, 2424 Erwin Road, Suite 602, Durham, NC 27705, USA
    Am J Epidemiol 170:598-606. 2009
    ..There is a clear need for further research on etiologic factors for ovarian cancer in African-American women...
  35. ncbi Estrogen and other female reproductive risk factors are not strongly associated with the development of rheumatoid arthritis in elderly women
    Linda A Merlino
    College of Public Health, University of Iowa, Iowa City, IA, USA
    Semin Arthritis Rheum 33:72-82. 2003
    ..Endogenous and exogenous reproductive hormones have been associated with rheumatoid arthritis (RA) in women, but data are inconsistent and no studies have assessed RA risk factors exclusively in elderly women...
  36. ncbi The clinical content of preconception care: reproductive history
    Phillip G Stubblefield
    Department of Obstetrics and Gynecology, Boston University Medical Center, Boston, MA 02118, USA
    Am J Obstet Gynecol 199:S373-83. 2008
    ..We review the evidence for the potential benefit of reproductive history in identifying strategies for evaluation and treatment to prevent recurrent adverse pregnancy outcome...
  37. ncbi Role and impact of menstrual and reproductive factors on breast cancer risk in Japan
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 16:116-23. 2007
    ..aged 40-69 years completed a self-administered questionnaire, which included items about menstrual and reproductive history. During 1990-2002, 441 newly diagnosed cases of breast cancer were identified...
  38. ncbi [Self-rated health among climacteric women affiliated with the Instituto Mexicano del Seguro Social]
    Svetlana Vladislavovna-Doubova
    Unidad de Investigación Epidemiológica, Servicios de Salud, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico
    Salud Publica Mex 50:390-6. 2008
    ..To evaluate self-rated health (SRH) in climacteric women and to identify the factors associated with negative SRH...
  39. ncbi Reproductive history and risk of second primary breast cancer: the WECARE study
    Joan A Largent
    Epidemiology Division, Department of Medicine, University of California, Irvine, Irvine, CA 92697 7555, USA
    Cancer Epidemiol Biomarkers Prev 16:906-11. 2007
    ..Women with an initial breast cancer diagnosis are at elevated risk of developing subsequent cancer in the contralateral breast. Studies of reproductive factors and contralateral breast cancer (CBC) have provided inconsistent results...
  40. pmc Role of reproductive factors in breast cancer in a low-risk area: a case-control study
    D N Rao
    Division of Epidemiology and Biostatistics, Tata Memorial Centre, Parel, Bombay, India
    Br J Cancer 70:129-32. 1994
    ..These findings, in a low-risk population, were consistent with those reported from high-risk populations...
  41. ncbi Reliability of data on medical conditions, menstrual and reproductive history provided by hospital controls
    C Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157, Milan, Italy
    J Clin Epidemiol 54:902-6. 2001
    To assess the reliability of data on medical conditions, and menstrual or reproductive history, a sample of 294 controls interviewed in hospital between 1989 and 1992 for an Italian case-control study on digestive tract neoplasms was re-..
  42. pmc Reproductive history and risk of three breast cancer subtypes defined by three biomarkers
    Amanda I Phipps
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M4 B402, Seattle, WA 98109 1024, USA
    Cancer Causes Control 22:399-405. 2011
    ..Using data from the Breast Cancer Surveillance Consortium, we explored associations between reproductive history and three breast cancer subtypes...
  43. ncbi National cohort study of reproductive risk factors for rheumatoid arthritis in Denmark: a role for hyperemesis, gestational hypertension and pre-eclampsia?
    K T Jørgensen
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark
    Ann Rheum Dis 69:358-63. 2010
    ..A study was undertaken to address the possible impact of live births, pregnancy losses and pregnancy complications on the subsequent risk of RA in a nationwide cohort study...
  44. ncbi SEARCH international case-control study of childhood brain tumours: role of index pregnancy and birth, and mother's reproductive history
    M McCredie
    Cancer Epidemiology Research Unit, New South Wales Cancer Council, Sydney, Australia
    Paediatr Perinat Epidemiol 13:325-41. 1999
    ..inter alia, the risk in relation to characteristics of the index pregnancy and birth, and maternal reproductive history. Subjects comprised 1218 cases aged 0-19 years and 2223 controls...
  45. ncbi Birth characteristics, maternal reproductive history, and the risk of infant leukemia: a report from the Children's Oncology Group
    Logan G Spector
    Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, 420 Delaware Street Southeast, MMC 715, Minneapolis, MN 55455, USA
    Cancer Epidemiol Biomarkers Prev 16:128-34. 2007
    ..Other variables of interest were not notably associated with infant leukemia regardless of MLL status. This investigation further supports the contention that molecularly defined subtypes of infant leukemia have separate etiologies...
  46. pmc Breast cancer risk by age at birth, time since birth and time intervals between births: exploring interaction effects
    G Albrektsen
    Department of Mathematics, University of Bergen, Johannes Brunsgt 12, 5008 Bergen, Norway
    Br J Cancer 92:167-75. 2005
    ..Increasing maternal age at the first and second childbirth was associated with an increase in risk in the long run, whereas no such long-term effect was seen with age at higher order births...
  47. pmc Menstrual and reproductive factors in relation to mammographic density: the Study of Women's Health Across the Nation (SWAN)
    Lesley M Butler
    Division of Epidemiology, Department of Public Health Sciences, University of California at Davis, One Shields Avenue, 1616 DaVinci Court, Davis, CA 95616, USA
    Breast Cancer Res Treat 112:165-74. 2008
    ..2, P<0.01 for >or=3 births versus no births). Our data support a mechanism for parity and breast cancer that involves mammographic density among pre- and early perimenopausal women that may be modified by body size...
  48. ncbi Reproductive history in relation to plasma hormone levels in healthy post-menopausal women
    R B Ness
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, 517 Parran Hall, 15261, Pittsburgh, PA, USA
    Maturitas 35:149-57. 2000
    We sought to examine the relationship between reproductive history and measures of selected gonadotrophins and steroid hormones among post-menopausal women...
  49. ncbi Reproductive and menstrual risk factors for pancreatic cancer: a population-based study of San Francisco Bay Area women
    Eric J Duell
    Department of Community and Family Medicine, Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, NH 03756, USA
    Am J Epidemiol 161:741-7. 2005
    ....
  50. ncbi Ethnic variations in mammographic density: a British multiethnic longitudinal study
    Valerie A McCormack
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Epidemiol 168:412-21. 2008
    ..densities were partly attributed to higher body mass index, less use of hormone therapy, and a protective reproductive history, but these factors did not account entirely for ethnic differences, since fully adjusted mean densities ..
  51. ncbi Prognosis of premenopausal breast cancer and childbirth prior to diagnosis
    Kelly Anne Phillips
    Peter MacCallum Cancer Centre, University of Melbourne, Carlton, Victoria 3053, Australia
    J Clin Oncol 22:699-705. 2004
    ..The time interval between last childbirth and subsequent breast cancer diagnosis is emerging as an important prognostic factor for premenopausal women...
  52. ncbi Female reproductive history and the skeleton-a review
    Magnus K Karlsson
    Department of Orthopaedics, Malmo University Hospital, Malmo, Sweden
    BJOG 112:851-6. 2005
  53. pmc Birth-related characteristics, congenital malformation, maternal reproductive history and neuroblastoma: the ESCALE study (SFCE)
    Caroline Munzer
    INSERM, U754, IFR69, Villejuif, France
    Int J Cancer 122:2315-21. 2008
    ..This study investigated the role of birth characteristics, congenital malformation and maternal reproductive history in neuroblastoma...
  54. ncbi Reproductive history of a healthy woman with mosaic duplication of chromosome 4p
    Laura Bernardini
    IRCCS CSS San Giovanni Rotondo and CSS Mendel, 261 00198 Rome, Italy
    Prenat Diagn 25:283-5. 2005
    ..We report on a young woman carrying a mosaic duplication of chromosome 4p, evaluated because of three abortions due to IUGR and fetal malformation...
  55. ncbi Hormone replacement therapy, reproductive history, and colorectal adenomas: data from the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial (United States)
    Mark P Purdue
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, MSC 7240, Executive Plaza South 8121, Rockville, MD 20892, USA
    Cancer Causes Control 16:965-73. 2005
    ....
  56. ncbi Reproductive history, occupational exposures, and thyroid cancer risk among women textile workers in Shanghai, China
    E Y Wong
    Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA, USA
    Int Arch Occup Environ Health 79:251-8. 2006
    ..We conducted a case-cohort study nested in a cohort of 267,400 female textile workers in Shanghai, China, who had been followed for cancer incidence during 1989-1998...
  57. ncbi Ovulation and risk of epithelial ovarian cancer
    David M Purdie
    Queensland Institute of Medical Research, Royal Brisbane Hospital, Herston, Queensland, Australia
    Int J Cancer 104:228-32. 2003
    ..These findings support the theory that incessant ovulation is a major contributor to the occurrence of ovarian cancer and suggest that ovulations during the 20s may be those most associated with disease risk...
  58. ncbi Reproductive risk factors for epithelial ovarian cancer according to histologic type and invasiveness
    F Modugno
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Ann Epidemiol 11:568-74. 2001
    ..We examined reproductive risk factors for epithelial ovarian cancer according to histologic subtype and tumor invasiveness...
  59. ncbi Modification of BRCA1- and BRCA2-associated breast cancer risk by AIB1 genotype and reproductive history
    T R Rebbeck
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Cancer Res 61:5420-4. 2001
    ..Our results support the hypothesis that pathways involving endocrine signaling, as measured through AIB1 genotype and reproductive history, may have a substantial effect on BRCA1/2-associated breast cancer risk.
  60. ncbi Use of time to pregnancy in environmental epidemiology and surveillance
    Mike Joffe
    Department of Epidemiology and Public Health, Imperial College, St Mary s Campus, Norfolk Place, London W2 1PF, UK
    J Public Health (Oxf) 30:178-85. 2008
    ..Time to pregnancy (TTP) is a validated measure of biological fertility that can be studied with relatively small populations...
  61. ncbi Comparison of women's breast cancer risk factors in Geneva, Switzerland and Shanghai, China
    Lisa A DeRoo
    Division of Clinical Epidemiology, Department of Community Medicine, Geneva University Hospitals, Geneva, Switzerland
    Prev Med 51:497-501. 2010
    ..We compared the prevalence of known and suspected breast cancer risk factors among women in Geneva, Switzerland, where the annual incidence of breast cancer is high, to women in Shanghai, China, where incidence is lower...
  62. ncbi Reproductive history and cutaneous malignant melanoma: a comparison between women and men
    Jeanette Kaae
    Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark
    Am J Epidemiol 165:1265-70. 2007
    ..g., patterns of sun exposure), the authors investigated the effect of reproductive history (parenthood) on CMM risk in both women and men...
  63. ncbi Reproductive history, socioeconomic status and disability in the women aged 65 years or older in Turkey
    Belgin Akin
    School of Health Nursing Department, University of Selcuk, Alaeddin Keykubad Campus, 42079 Selcuklu Konya, Turkey
    Arch Gerontol Geriatr 50:11-5. 2010
    ..study is to examine the relationship between functional disabilities in women over the age of 65 and their reproductive history and socioeconomic status. This is a cross-sectional study...
  64. ncbi Impact of menstrual and reproductive factors on breast cancer risk in Japan: results of the JACC study
    Koji Tamakoshi
    Department of Public Health Health Information Dynamics, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550
    Cancer Sci 96:57-62. 2005
    ....
  65. ncbi Reproductive history and health screening for women and mortality in the Japan Collaborative Cohort Study for Evaluation of Cancer (JACC)
    Fumio Sakauchi
    Department of Public Health, Sapporo Medical University School of Medicine, S1W17, Chuo Ku, Sapporo, 060 8556, Japan
    Asian Pac J Cancer Prev 8:129-34. 2007
    b>Reproductive history and participation in health screening for women were surveyed among female subjects, and interesting results were obtained in the present analyses...
  66. ncbi Breast cancer: critical data analysis concludes that estrogens are not the cause, however lifestyle changes can alter risk rapidly
    Richard A Wiseman
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    J Clin Epidemiol 57:766-72. 2004
    ..The theory that estrogens are causally associated with increased risk of breast cancer and the question of whether lifetime cumulative exposure is necessary are critically reviewed...
  67. ncbi Parity, other reproductive factors, and risk of pancreatic cancer mortality in a large cohort of U.S. women (United States)
    Lauren R Teras
    Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, Atlanta, GA 30329 4251, USA
    Cancer Causes Control 16:1035-40. 2005
    ..Furthermore, we find no evidence that other reproductive factors are associated with pancreatic cancer mortality...
  68. ncbi High-risk mammographic parenchymal patterns, hormone replacement therapy and other risk factors: a case-control study
    E Sala
    Department of Community Medicine, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK
    Int J Epidemiol 29:629-36. 2000
    ..Mammographic parenchymal patterns are of particular interest because the denser patterns reduce screening sensitivity as well as increasing breast cancer risk, and because they have been shown to be affected by exogenous oestrogens...
  69. ncbi Age at any birth is associated with breast cancer risk
    J Wohlfahrt
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen
    Epidemiology 12:68-73. 2001
    ....
  70. ncbi Characteristics of cystic breast disease with special regard to breast cancer development
    B Budai
    Clinical Research Department, National Institute of Oncology, Rath Gy. 7-9, 1122 Budapest, Hungary
    Anticancer Res 21:749-52. 2001
    ..Patients presented data about their menstrual status, reproductive history, lactation period, date of first and the number of BCF aspirations, gynaecological interventions, use of ..
  71. ncbi Cell proliferation, apoptosis, and expression of Bcl-2 and Bax in non-lactating human breast epithelium in relation to the menstrual cycle and reproductive history
    F Feuerhake
    Department of Neuropathology, Neurocenter, University of Freiburg, Freiburg, Germany
    Breast Cancer Res Treat 77:37-48. 2003
    ..in breast tissue of healthy premenopausal women in order to study the effect of the menstrual cycle and reproductive history on the cell turnover in the non-lactating mammary gland epithelium...
  72. ncbi Reproductive factors and family history of breast cancer in relation to plasma prolactin levels in premenopausal and postmenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 120:1536-41. 2007
    ..9 ng/mL vs. 14.3 ng/mL, p=0.04) but not postmenopausal (p=0.73) women. In conclusion, the associations of parity and family history with breast cancer risk may be mediated, at least in part, by prolactin levels...
  73. ncbi Reproductive risk factors for cutaneous melanoma in women: a case-control study
    C Suzanne Lea
    Statistics and Epidemiology Program, Research Triangle Institute International, Research Triangle Park, NC, USA
    Am J Epidemiol 165:505-13. 2007
    ..a questionnaire obtaining information about oral contraceptive use, hormone replacement therapy, reproductive history, sun exposure, occupation, and medical history from 318 Caucasian women newly diagnosed between 1991 and ..
  74. ncbi Reproductive factors and breast cancer risk among older women
    Sumitra Shantakumar
    Department of Epidemiology, CB 7435 McGavran Greenberg Hall, University of North Carolina School of Public Health, Chapel Hill, NC 27599 7435, USA
    Breast Cancer Res Treat 102:365-74. 2007
    ..Moreover, breastfeeding, one of the few potentially modifiable risk factors for breast cancer, was an important factor in decreasing risk among older parous postmenopausal women...
  75. ncbi Reproductive factors, exogenous hormone use and bladder cancer risk in a prospective study
    Marie M Cantwell
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Int J Cancer 119:2398-401. 2006
    ..62-2.43) and 0.57 (95% CI = 0.14-2.34), respectively, compared with nonusers (p = 0.50). Findings from this study are not consistent with the hypothesis that hormone-related factors in women are associated with bladder cancer...
  76. ncbi Oral contraceptives, reproductive factors, and risk of colorectal cancer among women in a prospective cohort study
    Jennifer Lin
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Am J Epidemiol 165:794-801. 2007
    ..09). No significant association was observed between reproductive factors and colorectal cancer risk. These findings provide some support for a potential role of OCs in reducing risk of colorectal cancer...
  77. ncbi Reproductive history, infertility treatment, and the risk of acute leukemia in children with down syndrome: a report from the Children's Oncology Group
    Susan E Puumala
    Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
    Cancer 110:2067-74. 2007
    ..There is mixed evidence for associations between reproductive history or infertility and acute leukemia among children without DS.
  78. ncbi Statin use and risk of breast cancer
    Gaia Pocobelli
    Department of Epidemiology, University of Washington, Seattle, Washington, USA
    Cancer 112:27-33. 2008
    ..We analyzed data from a population-based case-control study to evaluate the association between the use of statins and breast cancer risk...
  79. pmc Non-Hodgkin lymphoma in women: reproductive factors and exogenous hormone use
    Jennifer S Lee
    Division of Endocrinology, Clinical Nutrition, and Vascular Medicine, Department of Internal Medicine, University of California Davis, Sacramento, CA, USA
    Am J Epidemiol 168:278-88. 2008
    ..51, 1.2), and of follicular lymphoma (OR = 0.75, 95% CI: 0.46, 1.2). Results suggest that endogenous and exogenous reproductive hormones confer different risks by NHL subtype and are associated with a reduced risk of DLCL in women...
  80. ncbi Reproductive factors and lower extremity arterial occlusive disease in women
    Gerold Holzer
    Department of Orthopedics, Medical University of Vienna, Waehringer Guertel 18 20, Vienna, 1090, Austria
    Eur J Epidemiol 22:505-11. 2007
    ..We quantify a direct relationship between reproductive variables including age at regular and premature menopause and the incidence of severe LEAOD among post-menopausal women...
  81. ncbi Risk factors associated with preterm birth in the Gaza Strip: hospital-based case-control study
    Kh Abu Hamad
    Ministry of Health, Gaza, Palestine
    East Mediterr Health J 13:1132-41. 2007
    ..Other significant risk factors included: short stature, short interval between the last 2 pregnancies, presence of congenital gynaecological abnormalities, previous history of caesarean delivery and previous history of stillbirth...
  82. ncbi Female reproductive factors and the risk of gastric cancer in a large-scale population-based cohort study in Japan (JPHC study)
    Christina Persson
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 17:345-53. 2008
    ..Although early estrogen exposure may have some protective effect, female reproductive factors may have no substantial influence on gastric cancer development...
  83. ncbi Heightened risk of breast cancer following pregnancy: could lasting systemic immune alterations contribute?
    Keren Shakhar
    Biobehavioral Medicine Program, Department of Oncological Sciences, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    Cancer Epidemiol Biomarkers Prev 16:1082-6. 2007
    ..The effect of age at FFTP on the immune function is currently understudied. Its potential relevance to the development of breast cancer stresses the need for further research...
  84. ncbi [Reproductive risk factors of breast cancer in patients attended at a second level urban hospital]
    Carlos Manuel Ortiz Mendoza
    Servicio de clínica de mama, Hospital General Tacuba, DF Mexico
    Ginecol Obstet Mex 75:11-6. 2007
    ..To evaluate the implication of reproductive risk factors for breast cancer of patients at a breast clinic of a second level urban hospital...
  85. pmc Reproductive and hormonal risk factors for postmenopausal luminal, HER-2-overexpressing, and triple-negative breast cancer
    Amanda I Phipps
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Cancer 113:1521-6. 2008
    ..Reproductive factors may plausibly be differentially correlated with the risk of different breast cancer subtypes because these factors are presumed to impact exposure to endogenous sex hormones...
  86. ncbi The influence of reproductive and hormonal factors on ovarian cancer survival
    C M Nagle
    Cancer and Population Studies Group, Queensland Institute of Medical Research, Brisbane, Australia
    Int J Gynecol Cancer 18:407-13. 2008
    ..We have studied survival according to hormonal and reproductive history in a population-based cohort of 676 Australian women aged 18-79, newly diagnosed with invasive epithelial ..
  87. ncbi Pregnancy levels of estrogen and progesterone: the double-edged sword
    Gianluigi Ferretti
    Cancer Epidemiol Biomarkers Prev 16:634; author reply 634-5. 2007
  88. ncbi Levels of zinc, selenium, calcium, and iron in benign breast tissue and risk of subsequent breast cancer
    Yan Cui
    Office of Health Assessment and Epidemiology, Los Angeles County Department of Public Health, Los Angeles, California, USA
    Cancer Epidemiol Biomarkers Prev 16:1682-5. 2007
    ..In conclusion, our data raise the possibility that relatively high levels of zinc, iron, and calcium in benign breast tissue may be associated with a modest increase in risk of subsequent breast cancer...
  89. ncbi Risk factors for first trimester miscarriage--results from a UK-population-based case-control study
    N Maconochie
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, UK
    BJOG 114:170-86. 2007
    ..The aim of this study was to examine the association between biological, behavioural and lifestyle risk factors and risk of miscarriage...
  90. ncbi Breast cancer risk factors in south of Islamic Republic of Iran: a case-control study
    K Mahouri
    Department of Community Medicine, Bandar Abbas School of Medicine, Bandar Abbas, Islamic Republic of Iran
    East Mediterr Health J 13:1265-73. 2007
    ....
  91. ncbi Multivariate analysis of reproductive risk factors for ovarian cancer in Alexandria, Egypt
    Fayek S El-Khwsky
    The Department of Medical Statistics, Medical Research Institute, Faculty of Medicine, Alexandria University, Egypt
    J Egypt Natl Canc Inst 18:30-4. 2006
    ..Different reproductive characteristics, life styles and specific medical conditions are responsible for different pattern and incidence of ovarian cancer worldwide...
  92. ncbi Prevalence and correlates of pregnancy loss history in a national sample of children and families
    Sarah Kye Price
    Washington University in St Louis, George Warren Brown School of Social Work, One Brookings Drive, Box 1196, St Louis, MO 63130, USA
    Matern Child Health J 10:489-500. 2006
    ..Findings from this study are discussed for their contribution to existing public health knowledge and the potential for future research focused on the experience of multiple loss and demographic groups at elevated risk...
  93. ncbi Gynecological characteristics related to breast cancer in pre and postmenopausal women
    Ismael Pascual Pastor Climente
    Servicio de Farmacia, Hospital Clinic Universitari, Valencia, Spain
    Clin Transl Oncol 8:416-22. 2006
    ....
  94. ncbi Menstrual and reproductive factors and risk of non-Hodgkin's lymphoma among Connecticut women
    Yawei Zhang
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT, USA
    Am J Epidemiol 160:766-73. 2004
    ..These findings support a reduced risk of non-Hodgkin's lymphoma associated with multiple pregnancies and an increased risk of non-Hodgkin's lymphoma associated with later age at menarche...
  95. ncbi Previous induced abortions and the risk of very preterm delivery: results of the EPIPAGE study
    Caroline Moreau
    Epidemiological Research Unit on Perinatal and Women s Health, INSERM U149, Villejuif, France
    BJOG 112:430-7. 2005
    ..To evaluate the risk of very preterm birth (22-32 weeks of gestation) associated with previous induced abortion according to the complications leading to very preterm delivery in singletons...
  96. ncbi Primary predictors of preterm labour
    Francois Goffinet
    Department of Obstetrics and Gynaecology, Maternity Port Royal, Cochin Saint Vincent de Paul Hospital, 123 Boulevard de Port Royal, 75014 Paris, France
    BJOG 112:38-47. 2005
    ..Before proposing new screening tests to be applied systematically to all pregnant women, their advantages and drawbacks must be fully evaluated...
  97. ncbi Isolated esophageal atresia and perinatal risk factors
    S Bianca
    Registro Siciliano Malformazioni Congenite ISMAC, Dipartimento di Pediatria, Catania, Italy
    Dis Esophagus 16:39-40. 2003
    ..We think that parity and low birth weight can be considered as risk factors for EA, and an accurate evaluation of reproductive history can be useful for the provision of genetic and perinatal counseling.
  98. ncbi Risk factors for vaginal trichomoniasis among women in Basra, Iraq
    N K Mahdi
    Department of Microbiology, College of Medicine, University of Basra, Basra, Iraq
    East Mediterr Health J 7:918-24. 2001
    ..The difference in the isolation rates of T. vaginalis in women with a history of abortion (7.6%) and in women with no history of abortion (15.7%) was statistically significant...
  99. ncbi Advanced paternal age and risk of fetal death: a cohort study
    Anne Marie Nybo Andersen
    Department of Social Medicine, University of Copenhagen, Copenhagen, Denmark
    Am J Epidemiol 160:1214-22. 2004
    ..88, 95% confidence interval: 0.93, 3.82), after adjustment for maternal age, reproductive history, and maternal lifestyle during pregnancy...
  100. ncbi Comparison between hospitalized and screening controls in studies assessing breast cancer risk
    Samantha Garbers
    Kaplan Comprehensive Cancer Center, New York University Medical Center, New York, USA
    Bull Cancer 91:E211-24. 2004
    ..In case-control studies, selection of an appropriate group of controls is a critical step which may affect the outcome of the analysis...
  101. ncbi Determining the main risk factors and high-risk groups of breast cancer using a predictive model for breast cancer risk assessment in South Korea
    Eun Ok Lee
    Seoul National University College of Nursing, 28 Yongon Dong, Chongno Gu, Seoul 110 744, South Korea
    Cancer Nurs 27:400-6. 2004
    ..Hence the predictive model in this group could not be generalized to the Korean population; instead, breast cancer incidence needs to be compared among nurses and teachers in a nurse-and-teacher cohort...

Research Grants66

  1. Self-report versus medical record data in a study of infant leukemia
    Anne M Jurek; Fiscal Year: 2010
    ....
  2. Protein Biomarkers of Cancer Risk in Older Persons
    Christopher Li; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  3. Depo-Provera and Breast Cancer: Epidemiology/Pathology
    Christopher Li; Fiscal Year: 2009
    ..such as parity and body mass index, modify this association?;and (3) Does the association between DMPA and breast cancer risk vary by histologic type or by the expression of steroid receptors including ERq, ERft, and PR? ..
  4. c-erbB-2 and Risk of Contralateral Breast Cancer
    Christopher Li; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  5. Pharmacogenetic Epidemiology of Birth Defects and Cancer
    Timothy Rebbeck; Fiscal Year: 2004
    ....
  6. Lymphoma in Autoimmune Disease: Consequence of Immune Suppression or Stimulation?
    Sasha Bernatsky; Fiscal Year: 2008
    ..Our proposed project will help identify patients at highest risk for lymphoma and provide guidance regarding initiation and maintenance of therapy to control SLE. [unreadable] [unreadable] [unreadable]..
  7. BOTULINUM TOXIN THERAPY FOR INTERSTITIAL CYSTITIS/CHRON*
    Mary FitzGerald; Fiscal Year: 2007
    ..abstract_text> ..
  8. Feasibility Study of Soccer Injuries
    Melissa Schiff; Fiscal Year: 2007
    ..Findings from this research will be used to for the development of a large, prospective cohort study to evaluate potentially modifiable risk factors for injury among female youth soccer players. [unreadable] [unreadable]..
  9. Risk for New onset of Depression in Perimenopausal Women
    Daniel Cramer; Fiscal Year: 2009
    ..abstract_text> ..
  10. The Acquisition of Bacterial Vaginosis in Lesbians
    Jeanne Marrazzo; Fiscal Year: 2006
    ..Lesbian couples provide a unique opportunity to conduct comparative studies of vaginal microbial ecology in sex partners, and to directly analyze determinants of transmission. ..
  11. Linkage Studies of Quantitative Ocular Traits
    Barbara Klein; Fiscal Year: 2006
    ..Subsequent follow-up with fine mapping of areas of interest in the genome is planned. ..
  12. Epidemiology of Ovarian Cancer:New Hypotheses
    MARY ROSSING; Fiscal Year: 2006
    ..abstract_text> ..
  13. Effect of hormonal contraception on bone mineral density
    Abbey Berenson; Fiscal Year: 2005
    ..Ultimately, this study will determine which women, if any, are placed at increased risk of osteopenia or osteoporosis as a result of using these hormonal contraceptives during their reproductive years. ..
  14. A RCT of LNG-IUD vs. DMPA for young postpartum women
    Nancy Stanwood; Fiscal Year: 2005
    ..Such a study could provide evidence for the safe and effective use of LNG-IUD in young postpartum women, leading to fewer unintended pregnancies. ..
  15. Genomic Markers of Breast Cancer Prevention Induced by hCG in Women at High Risk
    Jose Russo; Fiscal Year: 2008
    ..This knowledge will serve as the basis for establishing novel genomic signatures as intermediate biomarkers for larger preventive clinical trials at the completion of this project. [unreadable] [unreadable] [unreadable]..
  16. 14th International Society for Prenatal Diagnosis Meeting
    DIANA BIANCHI; Fiscal Year: 2008
    ..As a result of the conference, participants will be able to identify limitations and gaps in current practice and knowledge and develop a research agenda going forward. [unreadable] [unreadable] [unreadable]..
  17. Epigenetic Changes Induced by Estrogens and Xenoestrogens in Breast Cancer
    Jose Russo; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  18. SWAN Sleep Study II-UC Davis/Kaiser site
    Ellen Gold; Fiscal Year: 2008
    ..The results can inform primary prevention of adverse health outcomes due to the menopause-related sleep disturbances. ..
  19. Hormones, hormone-related genes, and colorectal cancer
    Jennifer Lin; Fiscal Year: 2008
    ..Findings from the proposed study of estrogen and progesterone will enhance our understanding of these lifestyle and genetic factors in relation to colorectal carcinogenesis. ..
  20. Lifestyle Factors and Type 2 Diabetes in Black Women
    Julie Palmer; Fiscal Year: 2008
    ..Because the follow-up and data collection are funded by another grant, the proposed large study of modifiable risk factors for type 2 diabetes can be carried out at a relatively modest cost. ..
  21. Neurobiology of Insomnia as Measured with FMRI
    Henry Orff; Fiscal Year: 2007
    ..Avenues for future investigation may include studies of insomnia subtypes (e.g., subjective versus objective) and/or new approaches to treatment of insomnia. [unreadable] [unreadable] [unreadable]..
  22. Impact of LEEP on cervical length and secretions
    Audrey Saftlas; Fiscal Year: 2007
    ..Paired statistical techniques, simple and multivariate linear regression, ANOVA, two-way repeated measures ANOVA, and ANCOVA will be used. [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
  23. Ovarian Failure Among Hysterectomized Women
    Patricia Moorman; Fiscal Year: 2007
    ..It should have considerable public health impact given the high frequency of the procedure and the important health consequences of early ovarian failure. ..
  24. Replication Study of Breast Cancer Susceptibility Genes in Blacks
    Dezheng Huo; Fiscal Year: 2010
    ..This study will advance understanding the genetic risk factors for breast cancer in women of African descent and will be invaluable in developing novel prevention strategies in the future. ..
  25. Hormone markers during pregnancy and ovarian concer risk
    Sven Cnattingius; Fiscal Year: 2005
    ..The Swedish research registers will allow us to perform a large cost-effective cohort study where information on markers of hormone exposure during pregnancy has been collected prospectively. ..
  26. Prenatal MF Exposure & Miscarriage Risk Among Women
    De Kun Li; Fiscal Year: 2009
    ..The findings from the proposed study will provide much needed confirmation of the recently reported results and advance our understanding of a MF health effect. ..
  27. CAM Use in Midlife Women in Five Ethnic Groups
    Ellen Gold; Fiscal Year: 2005
    ..abstract_text> ..
  28. Residential Mobility and Tracking of Adults
    Narayan Sastry; Fiscal Year: 2003
    ..Data from L.A.FANS-1 and ITS will also be used to investigate the determinants of individual residential mobility and migration among adults and the elderly and the determinants of residential turnover in Los Angeles neighborhoods. ..
  29. Serum Markers of Breast /Ovarian Cancer Risk
    Francesmary Modugno; Fiscal Year: 2003
    ..We also expect to identify additional related research questions, which we anticipate studying further in a multi-center, collaborative fashion within the various arms of the WHI. ..
  30. MUC-1 related cancer immunity: determinants and predictive significance
    Daniel Cramer; Fiscal Year: 2009
    ..The findings of our study could provide the basis for developing a safe cancer- preventing vaccine for ovarian cancer and perhaps other MUC1-expressing tumors. ..
  31. Physiology and Behavior of Maturation in Wild Baboons
    Jeanne Altmann; Fiscal Year: 2003
    ....
  32. Use of Antidepressants and Risk of Breast Cancer
    MARY ROSSING; Fiscal Year: 2003
    ..g., SSRIs or tricyclics), and individual drugs such as fluoxetine and paroxetine. Use of the pharmacy database will provide unbiased and complete exposure data relative to previous studies based on self-reported drug use. ..
  33. EPIDEMIOLOGY OF SMOKING CESSATION--GENETIC INFLUENCES
    MARY ROSSING; Fiscal Year: 2002
    ..In the future, such knowledge may allow the identification of subgroups of individuals who are most likely to benefit from particular pharmacologic interventions. ..
  34. HORMONE REPLACEMENT IN MENOPAUSAL WOMEN WITH EPILEPSY
    Cynthia Harden; Fiscal Year: 2002
    ..The outcome of this study will be determined by comparing seizure frequency in the baseline phase with the treated phase between placebo and hormone treated groups. ..
  35. ORAL CONTRACEPTIVES FOR DYSMENORRHEA IN ADOLESCENT GIRLS
    Anne Davis; Fiscal Year: 2002
    ..Given their efficacy in pregnancy prevention, safety, and non-contraceptive health benefits, COC may be an ideal therapy for primary dysmenorrhea in adolescent girls. ..
  36. EPIDEMIOLOGIC AND BIOLOGIC PREDICTORS OF IVF SUCCESS
    Daniel Cramer; Fiscal Year: 2002
    ....
  37. Prenatal diagnosis through selective DNA amplification
    Stephen Brown; Fiscal Year: 2009
    ..When and if such methods become available, they will revolutionize prenatal diagnosis and will represent a major milestone in the improvement of prenatal care. ..
  38. MOLECULAR EPIDEMIOLOGIC STUDY OF BREAST CANCER
    Wei Zheng; Fiscal Year: 2009
    ..Results from this study will be valuable in identifying high risk women for primary and secondary prevention of breast cancer. ..
  39. Family Clustering of Incidence & Progression of Cataract
    Barbara Klein; Fiscal Year: 2003
    ..We currently have no funds to support the proposed analyses. We believe this project offers the possibility of examining important hypotheses in a large group of families in a population-based framework. ..
  40. Contraceptive Practice /Delivery -- Community Pharmacies
    Jacqueline Gardner; Fiscal Year: 2005
    ..abstract_text> ..
  41. OVARIAN CANCER RISK AND SURVIVAL IN BRCA CARRIERS
    Francesmary Modugno; Fiscal Year: 2005
    ..Additionally, this training will provide the skills and experience needed to become an independent researcher in the molecular and genetic epidemiology of female cancers. ..
  42. Body size, physical activity, and Hodgkin's disease risk
    Sally Glaser; Fiscal Year: 2004
    ..abstract_text> ..
  43. Role of the Zic2 gene in CNS development & malformation
    Stephen Brown; Fiscal Year: 2005
    ..In addition, our studies will elucidate the cellular and molecular processes that result in HPE and will therefore be useful in understanding this and other brain malformations. ..
  44. MAMMOGRAPHIC DENSITITES IN CHINESE AND CAUCASIAN WOMEN
    Norman Boyd; Fiscal Year: 2002
    ..Information about selected risk factors and anthropometric variables will be collected by telephone interview. Mammograms will be obtained and digitized, and the volume of the breast and of dense tissue determined. ..
  45. A Community Study of Infertility in Northern Tanzania
    Ulla Larsen; Fiscal Year: 2004
    ..A basic protocol for the recommended treatment of infertility will be developed. 6. To analyze the social implications of infertility. 7. To assess the demographic implications of infertility. ..
  46. Models of Birthweight and Low Birthweight
    Narayan Sastry; Fiscal Year: 2004
    ..The first is the 1997 Natality Data Set (NDS), compiled from birth certificates by the National Center for Health Statistics. The second data source is the 1988 National Maternal and Infant Health Survey (NMIHS). ..
  47. DOMESTIC ABUSE IN PREGNANCY AND ADVERSE BIRTH OUTCOMES
    Audrey Saftlas; Fiscal Year: 2004
    ..abstract_text> ..
  48. Maternal-Fetal HLA Sharing and Risk of Preeclampsia
    Audrey Saftlas; Fiscal Year: 2004
    ..05. The proposed study may be the first to examine the effects of maternal-fetal HLA sharing in an adequately powered epidemiological framework. ..
  49. Socioeconomic and Ethnic Disparities in Adult Health
    Narayan Sastry; Fiscal Year: 2008
    ..L.A.FANS-2/Adult data will publicly released as quickly as possible once fieldwork is complete, to enable a wide range of researchers to conduct research. ..
  50. Biomarkers of Stress and Health for Los Angeles Children
    Narayan Sastry; Fiscal Year: 2008
    ..A.FANS data will provide an important new resource for a wide range of researchers to investigate the effects of social factors on children's stress, disease, and health. ..
  51. ANTIOXIDANTS AND FEMALE HORMONES IN THE ETIOLOGY OF RA
    Elizabeth Karlson; Fiscal Year: 2002
    ..RA will be confirmed by a screening questionnaire regarding rheumatic symptoms and review of medical records. The study will identify potentially modifiable risk factors for primary prevention of RA. ..
  52. P53 AND MOUSE MAMMARY TUMORIGENESIS
    Daniel Medina; Fiscal Year: 2004
    ..In summary, this model allows one to analyze the biological, genetic and molecular consequences of p53 gene deletion in the in situ mammary gland by taking advantage of transplantation methods. ..
  53. Sensory Testing in Subjects with Interstitial Cystitis
    Mary FitzGerald; Fiscal Year: 2004
    ..abstract_text> ..
  54. Prenatal NSAID Use and Miscarriage
    De Kun Li; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  55. Cancer Risk Reduction and Diet: A Cohort Study of Women
    Wei Zheng; Fiscal Year: 2007
    ..The results from this study may guide new strategies in the primary prevention of common cancer in both Western and Asian women. ..
  56. Cancer Incidence among Transplant Recipients:1990-2001
    LESLEY BUTLER; Fiscal Year: 2004
    ..abstract_text> ..
  57. Tumor Markers and Recurrent Adenomas: A Follow-up Study
    Wei Zheng; Fiscal Year: 2006
    ..This study is likely to provide valuable information for identifying high-risk adenoma patients for close surveillance and chemoprevention. ..
  58. ROLE OF MICROSATELLITE INSTABILITY IN BREAST CANCER
    Jose Russo; Fiscal Year: 2002
    ..The knowledge gained through this exploratory work will establish the basis for more in dept studies in the role of mismatch repair in breast cancer. ..
  59. Steroid Hormone Genes and Ovarian Cancer Risk
    Mary Anne Rossing; Fiscal Year: 2010
    ..The proposed study, by expanding our knowledge of the role of progestogens, estrogens, and androgens in the development of ovarian cancer, will inform efforts to develop effective strategies to prevent this disease. ..
  60. Fox Chase Cancer Center Breast Cancer Tissue Resources
    Jose Russo; Fiscal Year: 2008
    ..abstract_text> ..
  61. Hormones, DNA Repair, BRCA1/2 and Ovarian Cancer Preven*
    Francesmary Modugno; Fiscal Year: 2003
    ..Detailed data on gynecologic and reproductive history have already been obtained by the parent study using a standardized in-person interview...
  62. Prenatal Care for African American Women: Effect of Client-Provider Interaction
    Chin Hwa Yi; Fiscal Year: 2009
    ..In addition, this research addresses NINR scientific goals of reducing health disparities and improving quality of care, and is congruent with the mission of AHRQ which includes improving the outcomes and quality of health care. ..
  63. Neighborhood and Family Effects on Stress and Health
    Narayan Sastry; Fiscal Year: 2008
    ..abstract_text> ..
  64. MECHANISMS OF THE HORMONAL PREVENTION OF BREAST CANCER
    Daniel Medina; Fiscal Year: 2006
    ..The molecular understanding of the fundamental biological events involved in hormone-induced growth and differentiation will provide a rationale for developing new approaches for preventing human breast cancer. ..