electrooculography

Summary

Summary: Recording of the average amplitude of the resting potential arising between the cornea and the retina in light and dark adaptation as the eyes turn a standard distance to the right and the left. The increase in potential with light adaptation is used to evaluate the condition of the retinal pigment epithelium.

Top Publications

  1. ncbi A fully automated correction method of EOG artifacts in EEG recordings
    A Schlogl
    Institute of Human Computer Interfaces, Graz University of Technology, Krenngasse 37 IV, A 8010 Graz, Austria
    Clin Neurophysiol 118:98-104. 2007
  2. ncbi Optimization of an independent component analysis approach for artifact identification and removal in magnetoencephalographic signals
    Giulia Barbati
    Department of Neuroscience, AFaR Center of Medical Statistics and Information Technology, Fatebenefratelli Hospital, Isola Tiberina, Lungotevere degli Anguillara 12, 00153 Rome, Italy
    Clin Neurophysiol 115:1220-32. 2004
  3. ncbi Evidence for interacting cortical control of vestibular function and spatial representation in man
    J Ventre-Dominey
    INSERM and CNRS Cognitive Sciences Institute UMR 5015, 67 Bd Pinel, 69500, Bron, France
    Neuropsychologia 41:1884-98. 2003
  4. ncbi Fully automated reduction of ocular artifacts in high-dimensional neural data
    John W Kelly
    Department of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA
    IEEE Trans Biomed Eng 58:598-606. 2011
  5. ncbi Eye movement analysis for activity recognition using electrooculography
    Andreas Bulling
    Computer Laboratory, University of Cambridge, 15 JJ Thomson Ave, William Gates Building, Cambridge CB3 0FD, UK
    IEEE Trans Pattern Anal Mach Intell 33:741-53. 2011
  6. ncbi Improving the saccade peak velocity measurement for detecting fatigue
    Kati Hirvonen
    Brain Work Research Centre, Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, 00250 Helsinki, Finland
    J Neurosci Methods 187:199-206. 2010
  7. ncbi Basic parameters of saccadic eye movements--differences between unmedicated schizophrenia and affective disorder patients
    R Mahlberg
    Psychiatrische Klinik und Poliklinik der Freien Universität Berlin, Germany
    Eur Arch Psychiatry Clin Neurosci 251:205-10. 2001
  8. pmc Clinical evaluation of two consanguineous families with homozygous mutations in BEST1
    Teresa Piñeiro-Gallego
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Vigo, Spain
    Mol Vis 17:1607-17. 2011
  9. ncbi Ocular phenotype analysis of a family with biallelic mutations in the BEST1 gene
    Dror Sharon
    Department of Ophthalmology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Am J Ophthalmol 157:697-709.e1-2. 2014
  10. ncbi A homozygous frameshift mutation in BEST1 causes the classical form of Best disease in an autosomal recessive mode
    Hanna Bitner
    Department of Ophthalmology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Invest Ophthalmol Vis Sci 52:5332-8. 2011

Research Grants

  1. GYRATE ATROPHY OF THE CHOROID AND RETINA
    RICHARD WELEBER; Fiscal Year: 1980
  2. EYE MOVEMENT OF HYPERKINETIC CHILDREN
    Bernard Cohen; Fiscal Year: 1980
  3. Pilot Studies in Adaptation in Parabolic Flight
    Mark Shelhamer; Fiscal Year: 2004
  4. DYNAMICS OF BRAIN ACTIVATION DURING MOTOR IMAGERY
    Allen Osman; Fiscal Year: 2004
  5. Scaling in Reflexive and Volitional Eye Movements
    Mark Shelhamer; Fiscal Year: 2006
  6. Phase Transition Models of Oculomotor Control
    Mark Shelhamer; Fiscal Year: 2003
  7. Improved Search Coil Method for Measuring Eye Movements
    Mark Shelhamer; Fiscal Year: 2007
  8. Neuroanatomy of Emotion in Treatment Resistant Psychosis
    Stephan Taylor; Fiscal Year: 2006
  9. Classifying Psychiatric, Medical, and Primary Insomnias
    Jack Edinger; Fiscal Year: 2007
  10. Sensory Gating Mediated by Attention
    Patricia Davies; Fiscal Year: 2007

Detail Information

Publications213 found, 100 shown here

  1. ncbi A fully automated correction method of EOG artifacts in EEG recordings
    A Schlogl
    Institute of Human Computer Interfaces, Graz University of Technology, Krenngasse 37 IV, A 8010 Graz, Austria
    Clin Neurophysiol 118:98-104. 2007
    ..A fully automated method for reducing EOG artifacts is presented and validated...
  2. ncbi Optimization of an independent component analysis approach for artifact identification and removal in magnetoencephalographic signals
    Giulia Barbati
    Department of Neuroscience, AFaR Center of Medical Statistics and Information Technology, Fatebenefratelli Hospital, Isola Tiberina, Lungotevere degli Anguillara 12, 00153 Rome, Italy
    Clin Neurophysiol 115:1220-32. 2004
    ....
  3. ncbi Evidence for interacting cortical control of vestibular function and spatial representation in man
    J Ventre-Dominey
    INSERM and CNRS Cognitive Sciences Institute UMR 5015, 67 Bd Pinel, 69500, Bron, France
    Neuropsychologia 41:1884-98. 2003
    ..e. in right cortical lesions with hemi-neglect syndrome. These results demonstrate in man, the existence of a cortical influence on vestibular function related to the mechanisms of spatial representation...
  4. ncbi Fully automated reduction of ocular artifacts in high-dimensional neural data
    John W Kelly
    Department of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA
    IEEE Trans Biomed Eng 58:598-606. 2011
    ..Through this evaluation, the novel adaptation of wavelet thresholding is shown to produce superior reduction of ocular artifacts when compared to regression, principal component analysis, and ICA...
  5. ncbi Eye movement analysis for activity recognition using electrooculography
    Andreas Bulling
    Computer Laboratory, University of Cambridge, 15 JJ Thomson Ave, William Gates Building, Cambridge CB3 0FD, UK
    IEEE Trans Pattern Anal Mach Intell 33:741-53. 2011
    ..Eye movement data were recorded using an electrooculography (EOG) system...
  6. ncbi Improving the saccade peak velocity measurement for detecting fatigue
    Kati Hirvonen
    Brain Work Research Centre, Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, 00250 Helsinki, Finland
    J Neurosci Methods 187:199-206. 2010
    ..The EOG measurements can be improved for detecting fatigue by using the overlap saccade paradigm. The SPV values measured with the EOG method appear to be somewhat more sensitive in detecting fatigue than the FIT method...
  7. ncbi Basic parameters of saccadic eye movements--differences between unmedicated schizophrenia and affective disorder patients
    R Mahlberg
    Psychiatrische Klinik und Poliklinik der Freien Universität Berlin, Germany
    Eur Arch Psychiatry Clin Neurosci 251:205-10. 2001
    ..Basic neurophysiologic parameters of saccades in schizophrenics, especially in unmedicated patients, have not been studied extensively...
  8. pmc Clinical evaluation of two consanguineous families with homozygous mutations in BEST1
    Teresa Piñeiro-Gallego
    Departamento de Bioquimica, Genética e Inmunología, Facultad de Biologia, Universidad de Vigo, Vigo, Spain
    Mol Vis 17:1607-17. 2011
    ..To describe the clinical and genetic findings in two consanguineous families with Best vitelliform macular dystrophy (BVMD) and homozygous mutations in the bestrophin-1 (BEST1) gene...
  9. ncbi Ocular phenotype analysis of a family with biallelic mutations in the BEST1 gene
    Dror Sharon
    Department of Ophthalmology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Am J Ophthalmol 157:697-709.e1-2. 2014
    ..To investigate the genetic cause and perform a comprehensive clinical analysis of a Danish family with autosomal recessive bestrophinopathy; to investigate whether Bestrophin may be expressed in normal human retina...
  10. ncbi A homozygous frameshift mutation in BEST1 causes the classical form of Best disease in an autosomal recessive mode
    Hanna Bitner
    Department of Ophthalmology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Invest Ophthalmol Vis Sci 52:5332-8. 2011
    ..The objective was to characterize the molecular and clinical features of patients with the classical form of Best disease that is inherited in an autosomal recessive mode...
  11. pmc Phenotypic variability due to a novel Glu292Lys variation in exon 8 of the BEST1 gene causing best macular dystrophy
    Elliott H Sohn
    Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine of University of Southern California, Los Angeles, CA 90033, USA
    Arch Ophthalmol 127:913-20. 2009
    ..To study the phenotypic characteristics of patients with a novel p.E292K mutation in BEST1...
  12. ncbi Removal of ocular artifacts from EEG using adaptive thresholding of wavelet coefficients
    V Krishnaveni
    Department of Electronics and Communication Engineering, PSG College of Technology, Coimbatore 4, India
    J Neural Eng 3:338-46. 2006
    ..Denoising EEG with the proposed algorithm yields better results in terms of ocular artifact reduction and retention of background EEG activity compared to non-adaptive thresholding methods and the JADE algorithm...
  13. ncbi Quantitative electro-oculography and electroencephalography as indices of alertness
    K Hyoki
    EEG Laboratory, Kawamuro Memorial Hospital, Niigata, Japan
    Electroencephalogr Clin Neurophysiol 106:213-9. 1998
    ..A broad band power that centers at the peak frequency may be a better measure for alertness assessment than powers in fixed bands...
  14. ncbi Differential effects of sleep deprivation on saccadic eye movements
    Elisabeth Zils
    Department of Neurology, University of Lubeck, Germany
    Sleep 28:1109-15. 2005
    ..This study was designed to show the influence of sleep deprivation on different types of saccadic eye movements...
  15. ncbi Automatic removal of eye movement and blink artifacts from EEG data using blind component separation
    Carrie A Joyce
    Department of Computer Science, University of California San Diego, La Jolla, California 92093 0114, USA
    Psychophysiology 41:313-25. 2004
    ....
  16. ncbi Nonsense-mediated decay as the molecular cause for autosomal recessive bestrophinopathy in two unrelated families
    Esther Pomares
    Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Invest Ophthalmol Vis Sci 53:532-7. 2012
    ..Strong evidence argues in favor of the dominant negative effects of most autosomal dominantly inherited mutations, whereas there is only weak support for the molecular basis of the ARB phenotype...
  17. ncbi Vigilance on the civil flight deck: incidence of sleepiness and sleep during long-haul flights and associated changes in physiological parameters
    N Wright
    Centre for Human Sciences, Defence Evaluation and Research Agency, Farnborough, UK
    Ergonomics 44:82-106. 2001
    ..The findings reported here might be applicable to other occupational environments where fatigue and sleepiness are known to occur...
  18. ncbi Unilateral vitelliform phenotype in autosomal recessive bestrophinopathy
    Maria Lucia Cascavilla
    Department of Ophthalmology, University Vita Salute San Raffaele, San Raffaele Scientific Institute, Milan, Italy
    Ophthalmic Res 48:146-50. 2012
    ..It was the aim of this study to report on a patient in whom a novel mutation in the BEST1 gene was responsible for unilateral vitelliform phenotype in autosomal recessive bestrophinopathy (ARB)...
  19. ncbi Autosomal recessive bestrophinopathy: differential diagnosis and treatment options
    Camiel J F Boon
    Department of Ophthalmology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Ophthalmology 120:809-20. 2013
    ..To describe the clinical and genetic characteristics of patients with autosomal recessive bestrophinopathy (ARB)...
  20. pmc Autosomal dominant Best disease with an unusual electrooculographic light rise and risk of angle-closure glaucoma: a clinical and molecular genetic study
    Sancy Low
    NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, UK
    Mol Vis 17:2272-82. 2011
    To describe the clinical and molecular characteristics of two families with autosomal dominant Best disease and atypical electrooculography (EOG).
  21. ncbi Monitoring sleepiness with on-board electrophysiological recordings for preventing sleep-deprived traffic accidents
    Christos Papadelis
    Aristotle University of Thessaloniki, School of Medicine, Laboratory of Medical Informatics, PO Box 323, 54124 Thessaloniki, Greece
    Clin Neurophysiol 118:1906-22. 2007
    ....
  22. ncbi Having to stop driving at night because of dangerous sleepiness--awareness, physiology and behaviour
    Torbjorn Akerstedt
    Stress Research Institute, Stockholm University, Stockholm, Sweden Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    J Sleep Res 22:380-8. 2013
    ..It was concluded that 44% of drivers during late-night driving became dangerously sleepy, and that this group showed higher perceived sleepiness and more sleep intrusions in the EEG/EOG. ..
  23. pmc Sensory system for implementing a human-computer interface based on electrooculography
    Rafael Barea
    Department of Electronics, University of Alcala, Alcala de Henares 28871, Madrid, Spain
    Sensors (Basel) 11:310-28. 2011
    This paper describes a sensory system for implementing a human-computer interface based on electrooculography. An acquisition system captures electrooculograms and transmits them via the ZigBee protocol...
  24. ncbi Effect of eye-blinks on a self-paced brain interface design
    Ali Bashashati
    Department of Electrical and Computer Engineering, University of British Columbia, 2332 Main Mall, Vancouver, BC, Canada
    Clin Neurophysiol 118:1639-47. 2007
    ..To test the performance of an EEG-based self-paced brain interface when data contaminated with eye-blink artefacts are included in the evaluation...
  25. ncbi Automatic sleep stage classification using two-channel electro-oculography
    Jussi Virkkala
    Sleep Laboratory, Brain Work Research Center, Finnish Institute of Occupational Health, Helsinki, Finland
    J Neurosci Methods 166:109-15. 2007
    ..63 and 73%. The automatic method can be further developed and applied for ambulatory sleep recordings by using only four disposable, self-adhesive and self-applicable electrodes...
  26. ncbi Functional neuroanatomy of learned helplessness
    Herbert Bauer
    Department of Psychology, University of Vienna, Liebiggasse 5, 1010, Vienna, Austria
    Neuroimage 20:927-39. 2003
    ....
  27. ncbi Spontaneous blinks as a criterion of visual fatigue during prolonged work on visual display terminals
    K Kaneko
    Department of Communications and Systems, The University of Electro-Communications, Chofu City, Tokyo, Japan
    Percept Mot Skills 92:234-50. 2001
    ..These experimental results suggested that the parameters regarding the EMG and the EOG for the spontaneous blinks were effective indices for assessing visual fatigue during prolonged VDT work...
  28. ncbi EMG and EOG artifacts in brain computer interface systems: A survey
    Mehrdad Fatourechi
    Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC, Canada V6T 1Z4
    Clin Neurophysiol 118:480-94. 2007
    ..b>Electrooculography (EOG) and electromyography (EMG) artifacts are considered among the most important sources of physiological ..
  29. ncbi Event related fMRI studies of voluntary and inhibited eye blinking using a time marker of EOG
    Jun Young Chung
    Department of Electrical Engineering, Korea Advanced Institute of Science and Technology, 373 1 Guseong dong, Yuseong Gu, Daejeon 305 701, South Korea
    Neurosci Lett 395:196-200. 2006
    ..The parietal area (precuneus and superior temporal gyrus) appears to be exclusively related to inhibited eye blinking...
  30. ncbi Genotype-phenotype correlation and longitudinal course in ten families with Best vitelliform macular dystrophy
    B Wabbels
    Department of Paediatric Ophthalmology, Strabismology and Ophthalmogenetics, University of Regensburg, Klinikum, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    Graefes Arch Clin Exp Ophthalmol 244:1453-66. 2006
    ..Longitudinal course and genotype-phenotype correlation in patients and carriers with heterozygous mutations in hBEST1 (bestrophin)...
  31. ncbi Computer-assisted sleep staging
    R Agarwal
    Stellate Systems, 345 Victoria Ave, Suite 300, Montreal, QC H3Z 2N2, Canada. ragarwalstellate.com
    IEEE Trans Biomed Eng 48:1412-23. 2001
    ..6% with manual scoring of 20-s epochs according to RK standard. The greatest amount of errors occurred in the identification of the highly transitional Stage 1, 54% of which was misclassified into neighboring stages 2 or Wake...
  32. ncbi Late onset is common in best macular dystrophy associated with VMD2 gene mutations
    Agnes B Renner
    Augenklinik, Charite Campus Benjamin Franklin, Universitatsmedizin Berlin, Berlin, Germany
    Ophthalmology 112:586-92. 2005
    ..To perform a detailed morphologic and functional evaluation of Best macular dystrophy (BMD) associated with mutations in the VMD2 gene...
  33. pmc Suppression of Ca2+ signaling in a mouse model of Best disease
    Youwen Zhang
    Department of Ophthalmology and Vision Science, University of Arizona, 655 N Alvernon Way, Suite 108, Tucson, AZ 85711, USA
    Hum Mol Genet 19:1108-18. 2010
    ....
  34. pmc Bestrophins and retinopathies
    Qinghuan Xiao
    Department of Cell Biology and Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, GA 30322, USA
    Pflugers Arch 460:559-69. 2010
    ....
  35. ncbi Removal of ocular artifacts from electro-encephalogram by adaptive filtering
    P He
    Department of Biomedical, Industrial and Human Factors Engineering, Wright State University, Dayton, Ohio, USA
    Med Biol Eng Comput 42:407-12. 2004
    ..The first three coefficients (up to M = 3) were significantly larger than any remaining coefficients...
  36. ncbi Gesture and metaphor comprehension: electrophysiological evidence of cross-modal coordination by audiovisual stimulation
    Carlos Cornejo
    Escuela de Psicologia, Pontificia Universidad Catolica de Chile, Av Vicuna Mackenna 4860, Macul, Santiago, Chile
    Brain Cogn 70:42-52. 2009
    ..Our data favor the idea that meaning construction is globally integrative and highly context-sensitive...
  37. ncbi Automatic detection of motion direction changes in the human brain
    P Pazo-Alvarez
    Department of Clinical Psychology and Psychobiology, Faculty of Psychology, University of Santiago de Compostela, Campus Universitario Sur, S N, 15782 Santiago de Compostela, Galicia, Spain
    Eur J Neurosci 19:1978-86. 2004
    ..The present results suggest that a change-detection mechanism sensitive to unattended changes in motion direction may exist in the human visual system...
  38. ncbi Clinical and molecular genetic analysis of best vitelliform macular dystrophy
    Camiel J F Boon
    Department of Ophthalmology, Radboud University Nijmegen Medical Centre, The Netherlands
    Retina 29:835-47. 2009
    ..To describe the phenotype of Best vitelliform macular dystrophy (BVMD) and to evaluate genotype-phenotype and histopathologic correlations...
  39. ncbi Neural correlates of eye blinking; improved by simultaneous fMRI and EOG measurement
    Hyo Woon Yoon
    fMRI Laboratory of Brain Science Research Center, Korea Advanced Institute of Science and Technology, Daejeon, South Korea
    Neurosci Lett 381:26-30. 2005
    ..Based on these results, we conclude that the medial frontal gyrus is responsible for spontaneous eye blinking, whereas precentral activation appears to be related to blink inhibition...
  40. ncbi A rule-based automatic sleep staging method
    Sheng Fu Liang
    Department of Computer Science and Information Engineering, National Cheng Kung University, Tainan 701, Taiwan
    J Neurosci Methods 205:169-76. 2012
    ..68% and 0.79, respectively. This method can integrate with portable PSG system for sleep evaluation at-home in the near future...
  41. ncbi Localization of multifocal electroretinogram abnormalities to the lesion site: findings in a family with Best disease
    Inna V Glybina
    Kresge Eye Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Arch Ophthalmol 124:1593-600. 2006
    ....
  42. ncbi A new method for accurate and fast measurement of 3D eye movements
    Soo Chan Kim
    Graduate School of Bio and Information Technology, Hankyong National University, Ansung, South Korea
    Med Eng Phys 28:82-9. 2006
    ..The resolutions of horizontal, vertical, and torsional eye movement were 0.2 degrees, 0.2 degrees, and 0.1 degrees, respectively, with maximum ranges of +/- 35 degrees, +/- 25 degrees, and +/- 18 degrees...
  43. ncbi Morphological and functional changes in multifocal vitelliform retinopathy and biallelic mutations in BEST1
    Elisabeth Wittström
    Department of Ophthalmology, Lund University, Sweden
    Ophthalmic Genet 32:83-96. 2011
    ..To describe morphological and functional changes in a single patient with multifocal Best vitelliform macular dystrophy (BVMD) and to perform a genotype/phenotype correlation...
  44. ncbi [Best's disease with normal EOG. Case report of familial macular dystrophy]
    K Pollack
    Universitatsaugenklinik, Dresden
    Ophthalmologe 102:891-4. 2005
    ..Molecular genetic analysis also found Best's disease with a normal EOG. A normal EOG cannot exclude Best's disease. The family members should receive genetic consultation and if wished analysis of the VMD2 gene...
  45. pmc ISCEV Standard for Clinical Electro-oculography (EOG) 2006
    Malcolm Brown
    Dept of Clinical Engineering, Royal Liverpool University Hospital, Liverpool, L7 8XP, UK
    Doc Ophthalmol 113:205-12. 2006
    ..This 2006 Standard, from the International Society for Clinical Electrophysiology of Vision (ISCEV: www.iscev.org ), is a revision of the previous Standard published in 1993, and reviewed and re-issued in 1998...
  46. ncbi Novel and homozygous BEST1 mutations in Chinese patients with Best vitelliform macular dystrophy
    Raymond L M Wong
    Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Kowloon, Hong Kong SAR, China
    Retina 30:820-7. 2010
    ..The purpose of this study was to investigate the BEST1 gene mutations in Chinese patients with Best vitelliform macular dystrophy (BVMD)...
  47. ncbi Variant phenotype of Best vitelliform macular dystrophy associated with compound heterozygous mutations in VMD2
    Patrik Schatz
    Department of Ophthalmology, Lund University Hospital, Lund, Sweden
    Ophthalmic Genet 27:51-6. 2006
    ..To characterize the phenotype of members of a Swedish family with Best macular dystrophy and two distinct mutations in VMD2...
  48. ncbi Clinical and electrophysiological findings in autosomal dominant vitreoretinochoroidopathy: report of a new pedigree
    B A Lafaut
    Department of Ophthalmology, Ghent University Hospital, Belgium
    Graefes Arch Clin Exp Ophthalmol 239:575-82. 2001
    ..To report the clinical and electrophysiological findings in a three-generation pedigree with autosomal dominant vitreoretinochoroidopathy...
  49. ncbi Clinical and genetic heterogeneity in multifocal vitelliform dystrophy
    Camiel J F Boon
    Department of Ophthalmology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Arch Ophthalmol 125:1100-6. 2007
    ..To describe the clinical and genetic findings in 15 patients with multifocal vitelliform lesions...
  50. ncbi Endogenous and exogenous attention shifts are mediated by the same large-scale neural network
    Marius V Peelen
    Department of Psychology, Vrije Universiteit, Amsterdam, The Netherlands
    Neuroimage 22:822-30. 2004
    ..Within these regions, equally strong activation was observed for both orienting conditions. It is concluded that endogenous and exogenous orienting are mediated by the same large-scale network of frontal and parietal brain areas...
  51. ncbi Best's vitelliform macular dystrophy caused by a new mutation (Val89Ala) in the VMD2 gene
    L Eksandh
    Department of Ophthalmology, University Hospital, Lund, Sweden
    Ophthalmic Genet 22:107-15. 2001
    ..To describe the clinical phenotype in a family with Best's vitelliform macular dystrophy (BMD) and a new mutation (Val89Ala) in the VMD2 gene...
  52. ncbi Event-related potentials reveal involuntary processing of orientation changes in the visual modality
    Shimin Fu
    Beijing Laboratory of Cognitive Science, University of Science and Technology of China, Beijing, China
    Psychophysiology 40:770-5. 2003
    ..The underlying neural representation (i.e., the visual memory trace) seems to develop easier and decay faster than its auditory counterpart...
  53. ncbi [Electrooculography. Its value in the diagnosis of the patient with a balance disorder]
    E Domenech Campos
    Servicio de Otorrinolaringologia, Hospital Arnau de Vilanova, Valencia
    Acta Otorrinolaringol Esp 56:12-6. 2005
    Controversy persists on the value of electrooculography (EOG) in the diagnosis of the unbalanced patient. The aim of this study has been to know the utility of EOG in the diagnosis of patients with equilibrium disorders.
  54. ncbi A model-based objective evaluation of eye movement correction in EEG recordings
    Joep J M Kierkels
    Electrical Engineering Department, Eindhoven University of Technology, The Netherlands
    IEEE Trans Biomed Eng 53:246-53. 2006
    ..In general, the second-order blind identification correction algorithm in combination with 6 EOG electrodes performs best for all EEG configurations evaluated on the simulated data...
  55. ncbi System for assisted mobility using eye movements based on electrooculography
    Rafael Barea
    Electronics Department, University of Alcala, Alcala de Henares, 28871, Spain
    IEEE Trans Neural Syst Rehabil Eng 10:209-18. 2002
    This paper describes an eye-control method based on electrooculography (EOG) to develop a system for assisted mobility...
  56. ncbi A normal electro-oculography in a family affected by best disease with a novel spontaneous mutation of the BEST1 gene
    F Testa
    Department of Ophthalmology, Second University of Naples, Naples, Italy
    Br J Ophthalmol 92:1467-70. 2008
    ..To describe clinical and genetic findings in an Italian family affected by Best disease...
  57. ncbi Autosomal recessive best vitelliform macular dystrophy: report of a family and management of early-onset neovascular complications
    Alessandro Iannaccone
    Hamilton Eye Institute, Department of Ophthalmology, University of Tennessee Health Science Center, 930 Madison Avenue, Memphis, TN 38163, USA
    Arch Ophthalmol 129:211-7. 2011
    ....
  58. ncbi Evaluation of macular structure and function by OCT and electrophysiology in patients with vitelliform macular dystrophy due to mutations in BEST1
    Patrik Schatz
    Department of Ophthalmology, Glostrup Hospital, University of Copenhagen, Glostrup, Denmark
    Invest Ophthalmol Vis Sci 51:4754-65. 2010
    ..To analyze retinal structure and function in vitelliform macular dystrophy (VMD) due to mutations in BEST1...
  59. ncbi Clinical expression of Best's vitelliform macular dystrophy in Swedish families with mutations in the bestrophin gene
    V Ponjavic
    Department of Ophthalmology, University Hospital, Lund, Sweden
    Ophthalmic Genet 20:251-7. 1999
    ..To examine the clinical phenotype of three Swedish families with Best's vitelliform macular dystrophy (BMD) and three different mutations in the recently identified bestrophin gene...
  60. pmc Phenotypic variability in a French family with a novel mutation in the BEST1 gene causing multifocal best vitelliform macular dystrophy
    Emmanuelle Lacassagne
    Universite Paris Descartes, Faculté de Médecine Paris Descartes site Necker, CERTO, Paris, France
    Mol Vis 17:309-22. 2011
    ..To describe genetic and clinical findings in a French family affected by best vitelliform macular dystrophy (BVMD)...
  61. pmc Detailed analysis of retinal function and morphology in a patient with autosomal recessive bestrophinopathy (ARB)
    Christina Gerth
    Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, University of Toronto, Toronto, Canada
    Doc Ophthalmol 118:239-46. 2009
    ..For the first time, high-resolution imaging provided in vivo evidence of RPE and photoreceptor involvement in ARB...
  62. ncbi Neuropsychological correlates of an attention-related negative component elicited in an auditory oddball paradigm in schizophrenia
    Masato Higashima
    Department of Psychiatry and Neurobiology, Graduate School of Medical Science, Kanazawa University, 13 1 Takara machi, Kanazawa 920 8641, Japan
    Neuropsychobiology 51:177-82. 2005
    ..These results suggest that the latency prolongation of the attention-related, negative component induced in an auditory oddball paradigm may serve as an index for frontal dysfunction in schizophrenia...
  63. ncbi N400 deficits from semantic matching of pictures in probands and first-degree relatives from multiplex schizophrenia families
    Seidel Guerra
    Department of Biological Psychiatry, Cuban Neuroscience, Center Avenida 25, 152002 Cubanacan Playa, La Habana, Cuba
    Brain Cogn 70:221-30. 2009
    ..These results demonstrate an electrophysiological deficit in semantic match processing in clinically unaffected first-degree relatives of patients with schizophrenia, suggesting a possible use of this marker as endophenotype...
  64. ncbi Guidelines for calibration of stimulus and recording parameters used in clinical electrophysiology of vision
    Mitchell Brigell
    Pfizer Global Research and Development, Ann Arbor, MI 48105, USA
    Doc Ophthalmol 107:185-93. 2003
  65. ncbi Eye blink frequency during different computer tasks quantified by electrooculography
    J H Skotte
    National Institute of Occupational Health, Lersø Parkallé 105, 2100, Copenhagen Ø, Denmark
    Eur J Appl Physiol 99:113-9. 2007
    The purpose of the study was to evaluate electrooculography (EOG) as an automatic method to measure the human eye blink frequency (BF) during passive and interactive computer tasks performed at two screen heights...
  66. ncbi Issues relating to the subtraction phase in EOG artefact correction of the EEG
    Rodney J Croft
    Department of Cognitive Neuroscience and Behaviour, Imperial College Medical School, St Dunstans Road, W68RF, London, UK
    Int J Psychophysiol 44:187-95. 2002
    ..It is argued that such EOG correction error is small relative to both artefact rejection procedures and to normal variability found in ERP studies, and that it is less pernicious than artefact rejection procedures...
  67. ncbi Blinks of the eye predict blinks of the mind
    Lorenza S Colzato
    Leiden University, Cognitive Psychology Unit and Leiden Institute for Brain and Cognition, Leiden, The Netherlands
    Neuropsychologia 46:3179-83. 2008
    ..Thus, in line with our hypothesis, these data point to a modulatory role for DA in the AB...
  68. ncbi Genotype phenotype analysis of Bietti's crystalline dystrophy in patients with CYP4V2 mutations
    Timothy Y Y Lai
    Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Kowloon, Hong Kong
    Invest Ophthalmol Vis Sci 48:5212-20. 2007
    ..To evaluate the genotypic and phenotypic correlations of Bietti's crystalline dystrophy (BCD) in patients with the CYP4V2 gene by mutation screening and clinical and electrophysiological assessment...
  69. ncbi Isolated superior oblique palsies with electrophysiologically documented brainstem lesions
    F Thomke
    Department of Neurology, University of Mainz, Langenbeckstrasse 1, D 55101 Mainz, Germany
    Muscle Nerve 23:267-70. 2000
    ..Unilateral superior oblique palsy may be the only clinical sign of a brainstem lesion. Although such a cause may be underdiagnosed if based on MRI-documented lesions only, it remains a rare condition...
  70. ncbi Chloride channel activity of bestrophin mutants associated with mild or late-onset macular degeneration
    Kuai Yu
    Department of Cell Biology and The Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Invest Ophthalmol Vis Sci 48:4694-705. 2007
    ....
  71. ncbi An event-related potential study on the observation of erroneous everyday actions
    Ellen R A de Bruijn
    Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
    Cogn Affect Behav Neurosci 7:278-85. 2007
    ..The increased P300 amplitudes suggest a more general monitoring process that signals that the occurrence of unexpected events is involved in the detection of execution errors...
  72. ncbi Sleep medicine for surgeons
    Terence M Davidson
    Continuing Medical Education, University of California, San Diego, San Diego, California, USA
    Laryngoscope 118:915-31. 2008
    ..Because positive airway pressure remains the front line treatment, they must also develop expertise in the prescription of positive airway pressure therapy...
  73. ncbi Effects of information and reward on stimulus-preceding negativity prior to feedback stimuli
    Yasunori Kotani
    Department of Human System Science, Tokyo Institute of Technology, Tokyo, Japan
    Psychophysiology 40:818-26. 2003
    ..The results are discussed in terms of emotional anticipation, taking into consideration the result of self-report that subjects felt to be more motivated when they received precise information...
  74. ncbi Analysis of the first night effect and sleep parameters in medically refractory epilepsy patients
    Mary L Marzec
    Michael S Aldrich Sleep Disorders Center, Department of Neurology, University of Michigan Medical Center, 1500 E Medical Center Dr, Rm 8D 8702 Ann Arbor, MI 48109 0117, USA
    Sleep Med 6:277-80. 2005
    ..To assess the first night effect (FNE) and compare sleep stage proportions to normative values in a sample of medically refractory epilepsy patients...
  75. ncbi Interhemispheric interactions and redundancy gain: tests of an interhemispheric inhibition hypothesis
    Jeff Miller
    Department of Psychology, University of Otago, Dunedin, New Zealand
    Exp Brain Res 180:389-413. 2007
    ..The results suggest that such inhibition is unlikely to be the explanation for enhanced redundancy gain in split-brain individuals...
  76. ncbi Temperament and character in primary insomnia
    Zara de Saint Hilaire
    Sleep Laboratory, University Hospital of Geneva, Belle Idee, 2 chemin Petit Bel Air, 1225, Chene Bourg, Switzerland
    Eur Psychiatry 20:188-92. 2005
    ..Further studies are needed to see whether harm avoidance could be a psychological vulnerability marker for primary insomnia and be used as predictor of SSRI treatment responders...
  77. ncbi Comparing MSLT and ESS in the measurement of excessive daytime sleepiness in obstructive sleep apnoea syndrome
    S Y Y Fong
    Department of Psychiatry, Shatin Hospital, Chinese University of Hong Kong, Shatin, Hong Kong, China
    J Psychosom Res 58:55-60. 2005
    ....
  78. ncbi Influence of directional orientations during gait initiation and stepping on movement-related cortical potentials
    Omar Feix do Nascimento
    Center for Sensory Motor Interaction SMI, Department of Health Science and Technology HST, Aalborg University AAU, Fredrik Bajers Vej 7D 3, 9220 Aalborg, Denmark
    Behav Brain Res 161:141-54. 2005
    ....
  79. ncbi Accelerated and amplified neural responses in visual discrimination: Two features are processed faster than one
    Nancy J Lobaugh
    Imaging Research and Cognitive Neurology, Sunnybrook and Women s College Health Sciences Centre, 2075 Bayview Avenue Room A421, Toronto, Ontario, Canada M4N 3M5
    Neuroimage 26:986-95. 2005
    ..These data demonstrate the human visual system conjoins features rapidly, accelerating and amplifying the processing of relevant stimulus dimensions...
  80. ncbi Attention and non-REM sleep in neuroleptic-naive persons with schizophrenia and control participants
    Geneviève Forest
    Centre de Recherche Fernand Seguin, Hopital Louis H Lafontaine, 7331 Hochelaga, Montreal, Quebec, Canada H1N 3V2
    Psychiatry Res 149:33-40. 2007
    ..These results support the existence of a relationship between non-rapid-eye-movement sleep and cognitive performance in healthy individuals as well as in persons with schizophrenia...
  81. ncbi Visual and computer-based detection of slow eye movements in overnight and 24-h EOG recordings
    E Magosso
    Department of Electronics, Computer Science and Systems, University of Bologna, Viale Risorgimento 2, I 40136 Bologna, Italy
    Clin Neurophysiol 118:1122-33. 2007
    ..The present work aimed to evaluate the performance of an automatic slow eye movement (SEM) detector in overnight and 24-h electro-oculograms (EOG) including all sleep stages (1, 2, 3, 4, REM) and wakefulness...
  82. ncbi Activation of 5-HT1A receptors in the paragigantocellularis lateralis decreases shivering during cooling in the conscious piglet
    J M Hoffman
    Department of Physiology, Dartmouth Medical School, One Medical Center Drive, Lebanon, NH, USA
    Am J Physiol Regul Integr Comp Physiol 293:R518-27. 2007
    ..Our data are consistent with the hypothesis that 5-HT neurons in the PGCL facilitate oscillating spinal motor circuits involved in shivering but are less involved in modulating sympathetically mediated thermoregulatory mechanisms...
  83. ncbi Oscillatory responses representing differential auditory processing in sleep
    Sirel Karakas
    Hacettepe University Specialization Area of Experimental Psychology, Cognitive Psychophysiology Research Unit, Beytepe, Ankara, Turkey
    Int J Psychophysiol 65:40-50. 2007
    ..With respect to the long-duration theta activity, and greater differentiation between the deviant- and standard-elicited stimuli, Stage 2 appeared to represent the more effortful cognitive processing...
  84. ncbi Nocturnal eating: sleep-related eating disorder or night eating syndrome? A videopolysomnographic study
    Roberto Vetrugno
    Sleep Disorders Center, Department of Neurological Sciences, University of Bologna, Italy
    Sleep 29:949-54. 2006
    ..To describe the clinical and videopolysomnographic characteristics of nocturnal eating episodes in sleep-related eating disorder...
  85. ncbi Prepulse inhibition and P50 suppression: commonalities and dissociations
    Bob Oranje
    Center for Neuropsychiatric Schizophrenia Research, Department of Psychiatry, Bispebjerg University Hospital, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark
    Psychiatry Res 143:147-58. 2006
    ..They are not intrinsically auditory phenomena, and both appear to involve frontal cortical activity. In contrast, N100 suppression is most likely based on refractory mechanisms intrinsic to the auditory system...
  86. pmc Pulse transit time and blood pressure changes following auditory-evoked subcortical arousal and waking of infants
    Barbara C Galland
    Department of Women s and Children s Health, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Sleep 30:891-7. 2007
    ..To establish a normal range of data in 3-month-old infants in relation to changes in cardiovascular measurements, with particular reference to pulse transit time (PTT), following subcortical arousals and awakenings from sleep...
  87. ncbi The effect of gender on autonomic and respiratory responses during sleep among both young and middle-aged subjects
    M Richard
    Centre d Etude du Sommeil et des Rythmes Biologiques, Hopital du Sacre Coeur de Montreal, Montreal, Que, Canada
    Sleep Med 8:760-7. 2007
    ..We investigated whether gender affects sleep-related cardiovascular and respiratory responses and whether these vary according to healthy subjects being young or middle-aged...
  88. ncbi ERP correlates of conscious error recognition: aware and unaware errors in an antisaccade task
    Tanja Endrass
    Humboldt Universitat zu Berlin, Institut fur Psychologie, Rudower Chaussee 18, 12489 Berlin, Germany
    Eur J Neurosci 26:1714-20. 2007
    ..Furthermore, it has been shown that this is only true for the late Pe, whereas the early Pe like the Ne/ERN is not modulated by error awareness...
  89. ncbi Stimulus intensity affects the latency but not the amplitude of the N2pc
    Benoit Brisson
    Research Center in Neuropsychology and Cognition, University of Montreal, Montreal, Quebec, Canada
    Neuroreport 18:1627-30. 2007
    ..The results reveal one way in which early sensory ERP amplitude differences are converted into later latency differences...
  90. ncbi Different effects of exogenous cues in a visual detection and discrimination task: delayed attention withdrawal and/or speeded motor inhibition?
    Rob H J van der Lubbe
    Utrecht University, The Netherlands
    J Cogn Neurosci 17:1829-40. 2005
    ....
  91. ncbi When and where perceptual load interacts with voluntary visuospatial attention: an event-related potential and dipole modeling study
    Shimin Fu
    ARCH Laboratory, MS 3F5, George Mason University, Fairfax, VA 22030 4444, USA
    Neuroimage 39:1345-55. 2008
    ..Results suggest that perceptual load affects voluntary visuospatial attention at an early (but not the earliest) processing stage and that the TPO gyrus mediates target selection at the discrimination stage...
  92. pmc Automatic analysis of single-channel sleep EEG: validation in healthy individuals
    Christian Berthomier
    PHYSIP SA, Paris, France
    Sleep 30:1587-95. 2007
    ..To assess the performance of automatic sleep scoring software (ASEEGA) based on a single EEG channel comparatively with manual scoring (2 experts) of conventional full polysomnograms...
  93. ncbi An unnecessary response is detected faster than an insufficient response
    Asuka Murata
    Graduate School of Education, Hokkaido University, Sapporo, Japan
    Neuroreport 16:1595-8. 2005
    ..Thus, these results suggest that the error-detection process is more sensitive to an unnecessary response than to an insufficient response...
  94. ncbi An event-related brain potential study of children's conservation
    Qiong Zhang
    Department of Psychology, Zhejiang University, Hangzhou, Zhejiang 310028, PR China
    Neurosci Lett 431:17-20. 2008
    ..The results indicate the existence of an ERP component that reflects weight conservation ability in children and a possible relationship between conservation ability and brain activation...
  95. ncbi A pilot study of inexpensive sleep-assessment devices
    Jack D Edinger
    Psychology Service, VA Medical Center, Durham, NC 27705, USA
    Behav Sleep Med 2:41-9. 2004
    ..These findings indicate that the selection of an alternative methodology should consider the sleep measure of interest in addition to the relative merits and drawbacks of each device...
  96. ncbi Induction of visual imagery during NREM sleep
    R Conduit
    School of Psychology, LaTrobe University, Bundoora, Victoria, Australia
    Sleep 20:948-56. 1997
    ..Results can be interpreted as evidence for a link between PGO activity and dreaming in humans or in terms of an arousal-window hypothesis of visual hallucinations...
  97. ncbi Circasemidian 12 h cycle of slow wave sleep under constant darkness
    Mitsuo Hayashi
    Department of Behavioral Sciences, Faculty of Integrated Arts and Sciences, Hiroshima University, 1 7 1, Kagamiyama, Higashi Hiroshima, Japan
    Clin Neurophysiol 113:1505-16. 2002
    ..New York, NY: Raven Press, 1989. p. 71-98) that afternoon sleep propensity might reflect the circasemidian 12h cycle of slow wave sleep (SWS)...
  98. ncbi Ketamine and MK-801 decrease acetylcholine release in the pontine reticular formation, slow breathing, and disrupt sleep
    Ralph Lydic
    Department of Anesthesiology, University of Michigan, Ann Arbor 48109, USA
    Sleep 25:617-22. 2002
    ..This study used in vivo microdialysis to test the hypothesis that ketamine alters acetylcholine (ACh) release in the medial pontine reticular formation (mPRF)...
  99. ncbi Relationship of epileptic seizures to sleep stage and sleep depth
    Daniela Minecan
    Department of Neurology, University of Michigan Medical School, USA
    Sleep 25:899-904. 2002
    ..To determine whether sleep influences seizures in a similar way to IEDs, we examined seizure rates in various stages of sleep in epilepsy patients undergoing overnight video-EEG-polysomnography (VPSG)...
  100. ncbi Changes in EEG power density during sleep laboratory adaptation
    M Toussaint
    Foundation for Applied Neuroscience Research in Psychiatry, Centre Hospitalier, Rouffach, France
    Sleep 20:1201-7. 1997
    ..Therefore, we conclude that data from all nights recorded should be included in assessing a subject's sleep...
  101. ncbi Patterns of performance degradation and restoration during sleep restriction and subsequent recovery: a sleep dose-response study
    Gregory Belenky
    Division of Neuropsychiatry, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910 7500, USA
    J Sleep Res 12:1-12. 2003
    ..These adaptive changes are hypothesized to restrict brain operational capacity and to persist for several days after normal sleep duration is restored, delaying recovery...

Research Grants69

  1. GYRATE ATROPHY OF THE CHOROID AND RETINA
    RICHARD WELEBER; Fiscal Year: 1980
    ..Mild improvement of electrooculography was seen but the significance is uncertain...
  2. EYE MOVEMENT OF HYPERKINETIC CHILDREN
    Bernard Cohen; Fiscal Year: 1980
    Eye movements of normal and hyperactive children are recorded with electrooculography (EOG) and compared for differences in ocular pursuit...
  3. Pilot Studies in Adaptation in Parabolic Flight
    Mark Shelhamer; Fiscal Year: 2004
    ..abstract_text> ..
  4. DYNAMICS OF BRAIN ACTIVATION DURING MOTOR IMAGERY
    Allen Osman; Fiscal Year: 2004
    ..Further information concerning its less known covert side may lead to unexpected insights about the motor system in general, including its possible roles in cognition. ..
  5. Scaling in Reflexive and Volitional Eye Movements
    Mark Shelhamer; Fiscal Year: 2006
    ..Since scaling changes with pathology, new means to assess vestibular or oculomotor pathology may result. ..
  6. Phase Transition Models of Oculomotor Control
    Mark Shelhamer; Fiscal Year: 2003
    ..The work represents a new direction for the PI because his past work has not dealt with the unique mathematical formulations required for this study. ..
  7. Improved Search Coil Method for Measuring Eye Movements
    Mark Shelhamer; Fiscal Year: 2007
    ..abstract_text> ..
  8. Neuroanatomy of Emotion in Treatment Resistant Psychosis
    Stephan Taylor; Fiscal Year: 2006
    ..abstract_text> ..
  9. Classifying Psychiatric, Medical, and Primary Insomnias
    Jack Edinger; Fiscal Year: 2007
    ..This project will provide a much-needed comparison of these two insomnia nosologies and the subtypes they define. Results also likely will provide important information for future insomnia classification efforts. ..
  10. Sensory Gating Mediated by Attention
    Patricia Davies; Fiscal Year: 2007
    ..Improved measures of sensory gating may lead to productive and cost efficient studies assessing treatment effectiveness. [unreadable] [unreadable] [unreadable]..
  11. Reliability of Cognitive ERPs in Children and Adults
    Patricia Davies; Fiscal Year: 2006
    ..This information will be helpful, especially when clinical populations (e.g., attention deficit disorders and learning disabilities) are included in developmental ERP studies. [unreadable] [unreadable]..
  12. NEUROIMAGING OF HIV AND COMORBID DISORDERS
    Lance Bauer; Fiscal Year: 2003
    ..An analysis of change scores across groups will permit a formal test of the effects of antiviral treatment on neurophysiological status. ..
  13. COGNITIVE EVENT-RELATED POTENTIALS AND BRAIN MATURATION
    Patricia Davies; Fiscal Year: 2002
    ..The PI will prepare manuscripts for peer reviewed journals reporting the results of these studies and supervise graduate students in related research projects. ..
  14. DOSE/RESPONSE EFFECTS OF BEHAVIORAL INSOMNIA THERAPY
    Jack Edinger; Fiscal Year: 2001
    ..We should also develop a better understanding of the time course over which treatment-related improvements might be expected for insomniacs in general and for specific primary insomniac subtypes. ..
  15. Effects of Anxiety on Interhemispheric Processing
    REBECCA COMPTON; Fiscal Year: 2004
    ..Application of the ERP methodology for measuring interhemispheric transmission is expected to produce a detailed picture of how emotional relevance affects the spread of information from one hemisphere to another. ..
  16. Sleep EEG Spectral Measures of Insomnia
    Jack Edinger; Fiscal Year: 2004
    ..abstract_text> ..
  17. Functional Neuroanatomy of Obsessive Compulsive Disorder
    Stephan Taylor; Fiscal Year: 2009
    ..Successful completion of the project should lead to an improved understanding of the role of specific brain regions in generating the symptoms of OCD. ..
  18. Mechanisms Underlying the Cognitive Function of Sleep
    Subimal Datta; Fiscal Year: 2009
    ....
  19. Behavioral Insomnia Therapy With Fibromyalgia
    Jack Edinger; Fiscal Year: 2009
    ..g., pain, fatigue). Results of this trial should provide insights into the pathophysiology and management of FM. ..
  20. Genetic Versus Phenotypic Markers of Relapse Risk
    Lance Bauer; Fiscal Year: 2009
    ....
  21. The Reinforcing Mechanisms of Smoking in Adult ADHD
    JEAN GEHRICKE; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  22. Disaster Planning and Management
    Garrick Wallstrom; Fiscal Year: 2007
    ..unreadable] The communication between HiFIDE and an external system will be PHIN-compliant.[unreadable] 3. To evaluate the utility of HiFIDE for estimating outbreak features from a spike in surveillance data. ..
  23. Childhood Physiology and Risk for Schizophrenia
    Randal Ross; Fiscal Year: 2008
    ..Clarification of this methodology may lead to a novel prenatal intervention strategy designed to decrease risk for adolescent and adult onset of psychosis. ..
  24. Neurology of Deficient Response Inhibition in ADHD
    STEWART MOSTOFSKY; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  25. Neurologic Basis of the Inhibitory Deficits in ADHD
    STEWART MOSTOFSKY; Fiscal Year: 2008
    ..abstract_text> ..
  26. TREATMENTS FOR BENIGN PAROXYSMAL POSITIONAL VERTIGO
    Helen Cohen; Fiscal Year: 2008
    ..4. Determine the influence of rhinosinusitis. A) Determine the prevalence of rhinosinusitis in patients with BPPV. B) Determine if the presence of rhinosinusitis affects severity of symptoms or response to treatment. ..
  27. The nature and time course of phonological representations in reading
    Keith Rayner; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  28. Identifying molecular path of behavioural phenotype in schizophrenia
    L Hong; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  29. Brain Potentials (ERPS) Language, Memory, and Aging
    Marta Kutas; Fiscal Year: 2009
    ..This normative database will be of value for the assessment of adults of all ages with semantic/language processing disorders. ..
  30. A Novel Animal Model of Relevance to Schizophrenia
    David Feifel; Fiscal Year: 2009
    ..The successful development of this animal model could significantly enhance the understanding of the underlying causes of schizophrenia-associated abnormalities and improve drug discovery. ..
  31. CHOLINERGIC MECHANISMS OF BREATHING DURING SLEEP
    Ralph Lydic; Fiscal Year: 2010
    ..Aim 4 will use pontine and systemic drug administration to test the hypothesis that pontine cholinergic mechanisms modulate the ability of adenosine AI receptors to alter arousal and breathing. ..
  32. Relating sleep disordered breathing to daytime function
    INDU A AYAPPA; Fiscal Year: 2010
    ..Validating a measure of sleep disordered breathing that relates to sleepiness will help improve the diagnosis and treatment of obstructive sleep apnea. ..
  33. PSYCHOLOGICAL AND NEURAL BASES OF SPATIAL COGNITION
    Marlene Behrmann; Fiscal Year: 2010
    ..Acquired attentional deficits are notoriously difficult to rehabilitate, with profound adverse consequences for the individual, and targeted intervention efforts are urgently needed. ..
  34. Emotional and attentional biases to drug and trauma cues in addiction with PTSD
    Estate Sokhadze; Fiscal Year: 2006
    ..Decreased frontal topdown control further contributes to inability to override these automatic responses and addictive behaviors. [unreadable] [unreadable] [unreadable]..
  35. SEX HORMONES SLEEP AND CIRCADIAN RHYTHMICITY IN AGING
    Patricia Murphy; Fiscal Year: 2002
    ....
  36. CORTICAL & SUBCORTICAL BRAIN MECHANISMS UNDERLYING ADHD
    STEWART MOSTOFSKY; Fiscal Year: 2002
    ..Research will be conducted in a multidisciplinary environment enhanced by the addition of the F M. Kirby Center for Functional Brain Imaging. ..
  37. Perinatal Vulnerability to Psychosis
    Randal Ross; Fiscal Year: 2004
    ....
  38. Detection and Correction of Errors in Declarative Memory
    Jennifer Mangels; Fiscal Year: 2003
    ..the basic cognitive and neural principles underlying detection and correction of memory retrieval and monitoring errors, and have far reaching implications for populations that suffer memory and/or metacognitive deficits ..
  39. Updating Representations In Visual Working Memory
    Edward Vogel; Fiscal Year: 2005
    ..abstract_text> ..
  40. LANGUAGE PROCESSING DURING READING
    Keith Rayner; Fiscal Year: 2005
    ..The research should be useful in further understanding the process of skilled reading and also help to reveal the relationship between skilled and poor reading. ..
  41. SLEEP DEPRIVATION, EEG, & FUNCTIONAL MRI IN DEPRESSION
    Camellia Clark; Fiscal Year: 2005
    ..FMRI perfusion data will be analyzed by the analysis of variance algorithm in AFNI (Analysis of Functional Neural Images) software. ..
  42. Antipsychotic-Like Drug Effects of Neurotensin
    David Feifel; Fiscal Year: 2004
    ....
  43. OPIOID INDUCED REM SLEEP INHIBITION
    Ralph Lydic; Fiscal Year: 2005
    ..The potential health relatedness of these basic studies derives from the unwanted side effects of opioids on sleep and breathing. ..
  44. Liability Markers for Deficit Schizophrenia?
    L Hong; Fiscal Year: 2004
    ..We plan to use the preliminary data collected from this grant support to guide our full-scale search for phenotypic markers specifically associated with the liability for deficit schizophrenia and subsequent molecular genetic studies. ..
  45. CBT for Insomnia in Patients with Alcohol Dependence
    J Todd Arnedt; Fiscal Year: 2005
    ..abstract_text> ..
  46. BRAIN AND COGNITIVE MATURATION--8-17 YEARS OF AGE
    Beatriz Luna; Fiscal Year: 2003
    ..abstract_text> ..
  47. OCULAR MOTOR AND NEUROANATOMIC STUDIES OF SCHIZOPHRENIA
    BRETT CLEMENTZ; Fiscal Year: 2003
    ..In this regard, it will be especially important to refine stimulus conditions to the point where measurement error is reduced as much as is practically feasible, a goal toward which we will aspire with our proposed research. ..
  48. IMPACT OF LEUKEMIA TREATMENT ON THE CNS AND DEVELOPMENT
    KRISTINE KAEMINGK; Fiscal Year: 2003
    ..If the study can identify children at risk for cognitive and academic problems, those most in need of assistance can be provided with educational services and evaluation interventions. ..
  49. MEG STUDIES OF P50 SUPPRESSION IN SCHIZOPHRENIA
    BRETT CLEMENTZ; Fiscal Year: 2007
    ..In addition, dysfunction of left auditory cortex impedes proper inter-hemispheric communication, which interferes with the ability to generate normal recognition-type responses measured during oddball-type paradigms. ..
  50. DEVELOPMENT OF SUSTAINED ATTENTION IN INFANTS
    John Richards; Fiscal Year: 2006
    ....
  51. Automated (AI) Analysis of Sleep Disordered Breathing
    Indu Ayappa; Fiscal Year: 2004
    ..Successful completion of the training and research program will allow Dr. Ayappa to contribute independently to research in the field of sleep physiology. ..
  52. P20-Mediated Suppression of Vascular Force
    Christopher Rembold; Fiscal Year: 2004
    ..Many current treatments target smooth muscle to reduce tone. It is possible that targeting the force suppression pathway (i.e. p20) might provide comparable benefits. ..
  53. NEUROTROPHIN CONTROL OF REM SLEEP
    Jack Yamuy; Fiscal Year: 2004
    ..This concerted set of experiments will be critical in elucidating the role that neurotrophins play in the control of REM sleep. ..
  54. Neural correlates of cognitive biases in social phobia
    Jason Moser; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  55. Twin Study of ADHD, CD and Substance Abuse
    William G Iacono; Fiscal Year: 2010
    ..abstract_text> ..
  56. Treatment of Fear and Pain in Irritable Bowel Syndrome
    Bruce Naliboff; Fiscal Year: 2006
    ..abstract_text> ..
  57. PERINATAL ASSESSMENT OF AT RISK POPULATIONS
    WILLIAM FIFER; Fiscal Year: 2005
    ....
  58. Building a New Model for Diagnosis of ED Dizzy Patients
    David Newman Toker; Fiscal Year: 2007
    ..This research project and the research paradigms derived from it will form the nucleus of a career devoted to research in medical decision-making, causes of diagnostic errors, and methods to preventthem. ..
  59. The Nature of Phonological Representation in Reading
    M Ashby; Fiscal Year: 2004
    ..abstract_text> ..
  60. Electrophysiological Correlates of Anhedonia in Schizophrenia
    WILLIAM HORAN; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  61. TWIN FAMILY STUDY OF VULNERABILITY TO SUBSTANCE ABUSE
    William Iacono; Fiscal Year: 2007
    ..abstract_text> ..
  62. IMPACT OF SLEEP DISORDERS ON HEALTH
    Meir Kryger; Fiscal Year: 2002
    ....
  63. Impact of Obesity and Sleep Disorders on Health
    Meir Kryger; Fiscal Year: 2008
    ..This research may show that OSAS is a cause of the high death rate in obesity, making OSAS, not just obesity, a major public health problem. [unreadable] [unreadable] [unreadable]..
  64. Functional brain imaging based on fast optical signals
    Gabriele Gratton; Fiscal Year: 2008
    ..d) To significantly improve the signal-to-noise ratio (S/N) of optical signals through radical modifications of the current instrumental designs and improvements in recording and filtering methods. (RFA GOAL#6). ..
  65. Auditory Processing of Biological and Linguistic Stimuli
    Lisa Sanders; Fiscal Year: 2004
    ..By using fMRI, it will possible to determine which cortical areas are involved in processing auditory stimuli are involved in processing auditory stimuli with specific physical features and for specific goals. ..
  66. OPTICAL AND ELECTRICAL MEASURES OF BRAIN FUNCTION
    Gabriele Gratton; Fiscal Year: 2002
    ..are the minimum temporal and spatial separations between the activities in different areas that are discriminable with EROS? (C) Can EROS be used to detect patterns of correlation and coherence between the activity in different areas? ..
  67. OPTICAL AND ELECTRICAL MEASURES OF BRAIN FUNCTION
    Gabriele Gratton; Fiscal Year: 2003
    ..are the minimum temporal and spatial separations between the activities in different areas that are discriminable with EROS? (C) Can EROS be used to detect patterns of correlation and coherence between the activity in different areas? ..
  68. The Sleep Heart Health Study (SHHS)
    STUART QUAN; Fiscal Year: 2007
    ..Accomplishing these goals will provide important information concerning the public health impact of SDB. [unreadable] [unreadable]..
  69. Behavioral correlates of fMRI response in cocaine users
    Rita Goldstein; Fiscal Year: 2006
    ..abstract_text> ..