body surface potential mapping

Summary

Summary: Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in Wolff-Parkinson-White syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (Braunwald, Heart Disease, 4th ed)

Top Publications

  1. ncbi Combination of the LSQR method and a genetic algorithm for solving the electrocardiography inverse problem
    Mingfeng Jiang
    Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, People s Republic of China
    Phys Med Biol 52:1277-94. 2007
  2. ncbi Electrical connections between pulmonary veins: implication for ostial ablation of pulmonary veins in patients with paroxysmal atrial fibrillation
    Atsushi Takahashi
    Cardiovascular Center, Tsuchiura Kyodo Hospital, Tsuchiura shi, Ibaraki Ken, Japan
    Circulation 105:2998-3003. 2002
  3. ncbi Contact force-controlled zero-fluoroscopy catheter ablation of right-sided and left atrial arrhythmia substrates
    Gunter Kerst
    Eberhard Karls Universitat Tubingen, Tubingen, Germany
    Heart Rhythm 9:709-14. 2012
  4. pmc Noninvasive electrocardiographic imaging (ECGI): application of the generalized minimal residual (GMRes) method
    Charulatha Ramanathan
    Cardiac Bioelectricity Research and Training Center, Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106 7207, USA
    Ann Biomed Eng 31:981-94. 2003
  5. ncbi Image integration increases efficacy of paroxysmal atrial fibrillation catheter ablation: results from the CartoMerge Italian Registry
    Emanuele Bertaglia
    Ospedale Civile di Mirano, Via Mariutto, 13 30035 Mirano, Italy
    Europace 11:1004-10. 2009
  6. ncbi Truncated total least squares: a new regularization method for the solution of ECG inverse problems
    Guofa Shou
    Department of Biomedical Engineering, Zhejiang University, Hangzhou, China
    IEEE Trans Biomed Eng 55:1327-35. 2008
  7. ncbi Body surface mapping versus the standard 12 lead ECG in the detection of myocardial infarction amongst emergency department patients: a Bayesian approach
    Simon D Carley
    Resuscitation 64:309-14. 2005
  8. pmc Risk assessment of ventricular arrhythmia using new parameters based on high resolution body surface potential mapping
    Malgorzata Fereniec
    Nalecz Institute of Biocybernetics and Biomedical Engineering PAS, Warsaw, Poland
    Med Sci Monit 17:MT26-33. 2011
  9. ncbi Factors affecting error in integration of electroanatomic mapping with CT and MR imaging during catheter ablation of atrial fibrillation
    E Kevin Heist
    Cardiac Arrhythmia Service and Cardiac Unit, Massachusetts General Hospital, Gray 109, 55 Fruit St, Boston, MA, 02114, USA
    J Interv Card Electrophysiol 17:21-7. 2006
  10. ncbi Characterization of left ventricular activation in patients with heart failure and left bundle-branch block
    Angelo Auricchio
    Division of Cardiology, University Hospital, Leipzigerstrasse 44, D 39120 Magdeburg, Germany
    Circulation 109:1133-9. 2004

Detail Information

Publications248 found, 100 shown here

  1. ncbi Combination of the LSQR method and a genetic algorithm for solving the electrocardiography inverse problem
    Mingfeng Jiang
    Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, People s Republic of China
    Phys Med Biol 52:1277-94. 2007
    ..In addition, by combing the LSQR with genetic algorithms (GA), the performance can be improved further. It suggests that their combination may provide a good scheme for solving the ECG inverse problem...
  2. ncbi Electrical connections between pulmonary veins: implication for ostial ablation of pulmonary veins in patients with paroxysmal atrial fibrillation
    Atsushi Takahashi
    Cardiovascular Center, Tsuchiura Kyodo Hospital, Tsuchiura shi, Ibaraki Ken, Japan
    Circulation 105:2998-3003. 2002
    ..However, the presence of electrical connections between the PVs, which may make achievement of PV disconnection difficult, has not been systematically evaluated...
  3. ncbi Contact force-controlled zero-fluoroscopy catheter ablation of right-sided and left atrial arrhythmia substrates
    Gunter Kerst
    Eberhard Karls Universitat Tubingen, Tubingen, Germany
    Heart Rhythm 9:709-14. 2012
    ..A novel radiofrequency ablation catheter capable of real-time tissue-tip contact force measurements may compensate for nonfluoroscopic safety issues...
  4. pmc Noninvasive electrocardiographic imaging (ECGI): application of the generalized minimal residual (GMRes) method
    Charulatha Ramanathan
    Cardiac Bioelectricity Research and Training Center, Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106 7207, USA
    Ann Biomed Eng 31:981-94. 2003
    ..Simultaneous use of these two complementary methods in clinical ECGI will ensure reliability and maximal extraction of diagnostic information in the absence of a priori information about a patient's condition...
  5. ncbi Image integration increases efficacy of paroxysmal atrial fibrillation catheter ablation: results from the CartoMerge Italian Registry
    Emanuele Bertaglia
    Ospedale Civile di Mirano, Via Mariutto, 13 30035 Mirano, Italy
    Europace 11:1004-10. 2009
    ....
  6. ncbi Truncated total least squares: a new regularization method for the solution of ECG inverse problems
    Guofa Shou
    Department of Biomedical Engineering, Zhejiang University, Hangzhou, China
    IEEE Trans Biomed Eng 55:1327-35. 2008
    ..This investigation suggests that TTLS is able to robustly reconstruct EPs from BSPs and is a promising alternative method for the solution of ECG inverse problems...
  7. ncbi Body surface mapping versus the standard 12 lead ECG in the detection of myocardial infarction amongst emergency department patients: a Bayesian approach
    Simon D Carley
    Resuscitation 64:309-14. 2005
    ..To determine if body surface mapping (BSM) is better than the standard 12 lead ECG in the diagnosis of acute myocardial infarction amongst emergency department patients...
  8. pmc Risk assessment of ventricular arrhythmia using new parameters based on high resolution body surface potential mapping
    Malgorzata Fereniec
    Nalecz Institute of Biocybernetics and Biomedical Engineering PAS, Warsaw, Poland
    Med Sci Monit 17:MT26-33. 2011
    ..This study proposes new parameters describing depolarization and repolarization inhomogeneity in high resolution body surface potential maps (HR BSPM) to identify MI patients threatened by VT...
  9. ncbi Factors affecting error in integration of electroanatomic mapping with CT and MR imaging during catheter ablation of atrial fibrillation
    E Kevin Heist
    Cardiac Arrhythmia Service and Cardiac Unit, Massachusetts General Hospital, Gray 109, 55 Fruit St, Boston, MA, 02114, USA
    J Interv Card Electrophysiol 17:21-7. 2006
    ..We sought to examine the effect of patient- and technique-related factors on integration accuracy of electroanatomic mapping with CT and MR imaging of the left atrium...
  10. ncbi Characterization of left ventricular activation in patients with heart failure and left bundle-branch block
    Angelo Auricchio
    Division of Cardiology, University Hospital, Leipzigerstrasse 44, D 39120 Magdeburg, Germany
    Circulation 109:1133-9. 2004
    ....
  11. ncbi Effect of cardiac motion on solution of the electrocardiography inverse problem
    Mingfeng Jiang
    Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China
    IEEE Trans Biomed Eng 56:923-31. 2009
    ..This study suggests that the inclusion of cardiac motion in solving the ECG inverse problem can lead to more accurate and acceptable inverse solutions...
  12. ncbi Electrophysiological evaluation of pulmonary vein isolation
    Dipen Shah
    Médecin Adjoint Agrégé, Electrophysiology Unit, Cardiology Service, Hopitaux Universitaires de Geneve, CH 1211 Genéve 24, Switzerland
    Europace 11:1423-33. 2009
    ..Each of these far-field components can be recognized in sinus rhythm as well as during ongoing atrial fibrillation. Finally, the creation of temporally stable and definitive PV isolation remains a currently unsolved problem...
  13. ncbi Electrocardiographic imaging of patients with heart failure with left bundle branch block and response to cardiac resynchronization therapy
    Niraj Varma
    Cardiac Bioelectricity Research Department, Case Western Reserve University, Cleveland, OH, USA
    J Electrocardiol 40:S174-8. 2007
    ..To determine this, we used electrocardiographic imaging (ECGI), which maps epicardial ventricular excitation noninvasively...
  14. ncbi On the possibility for computing the transmembrane potential in the heart with a one shot method: an inverse problem
    Bjørn Fredrik Nielsen
    Simula Research Laboratory, N 1325, Lysaker, Norway
    Math Biosci 210:523-53. 2007
    ..The problem of computing the transmembrane potential at an arbitrary time instance during a heart beat is still an open problem...
  15. pmc Differences between left and right ventricular chamber geometry affect cardiac vulnerability to electric shocks
    Blanca Rodriguez
    Tulane University, New Orleans, LA, USA
    Circ Res 97:168-75. 2005
    ..Knowledge regarding the location of the main postshock excitable area within the 3-D ventricular volume could be important for improving defibrillation efficacy...
  16. ncbi Diagnosing old MI by searching for a linear boundary in the space of principal components
    Mark P Donnelly
    School of Computing and Mathematics, University of Ulster, Jordanstown, UK
    IEEE Trans Inf Technol Biomed 10:476-83. 2006
    b>Body surface potential mapping (BSPM) is a technique employing multiple electrodes to capture, via noninvasive means, an indication of the heart's condition...
  17. ncbi Impact of heart rhythm status on registration accuracy of the left atrium for catheter ablation of atrial fibrillation
    Jun Dong
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Cardiovasc Electrophysiol 18:1269-76. 2007
    ..However, the impact of the heart rhythm change on the accuracy of left atrium (LA) registration has not been studied...
  18. ncbi Body surface distribution and response to drugs of ST segment elevation in Brugada syndrome: clinical implication of eighty-seven-lead body surface potential mapping and its application to twelve-lead electrocardiograms
    W Shimizu
    Department of Internal Medicine, National Cardiovascular Center, Suita, Osaka, Japan
    J Cardiovasc Electrophysiol 11:396-404. 2000
    ..Body surface distribution and magnitude of ST segment elevation and their reflection in 12-lead ECGs have not been clarified in Brugada syndrome...
  19. ncbi Improving the diagnosis of bundle branch block by analysis of body surface potential maps
    Victoria Donis
    Itaca, Universidad Politecnica de Valencia, Valencia, Spain
    J Electrocardiol 42:651-9. 2009
    ..whether mapping information, specifically QRS duration and observation data from maps obtained using body surface potential mapping (BSPM), can be helpful in BBB diagnosis...
  20. ncbi Capacitive ECG system with direct access to standard leads and body surface potential mapping
    Martin Oehler
    Institut für Elektrische Messtechnik und Grundlagen der Elektrotechnik, TU Braunschweig, Hans Sommer Str 66, 38106 Braunschweig, Germany
    Biomed Tech (Berl) 54:329-35. 2009
    ..The results show a very close correlation between both types of ECG measurements. It is concluded that the cECG lends itself to rapid screening in clinically unstable patients...
  21. ncbi Body surface mapping in the ED evaluation of the patient with chest pain: use of the 80-lead electrocardiogram system
    Wesley H Self
    Department of Emergency Medicine, University of Virginia Health Sciences Center, Charlottesville, 22908, USA
    Am J Emerg Med 24:87-112. 2006
    ..Output from BSM is displayed in a 12-lead ECG format, an 80-lead ECG format, and on color contour maps. The color contour maps can be displayed on a torso image or as a flat map...
  22. ncbi Remote magnetic navigation to guide endocardial and epicardial catheter mapping of scar-related ventricular tachycardia
    Arash Aryana
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, MA 02114, USA
    Circulation 115:1191-200. 2007
    ....
  23. ncbi Right and left ventricular activation sequence in patients with heart failure and right bundle branch block: a detailed analysis using three-dimensional non-fluoroscopic electroanatomic mapping system
    Cecilia Fantoni
    Division of Cardiology, University Hospital, Magdeburg, Germany
    J Cardiovasc Electrophysiol 16:112-9; discussion 120-1. 2005
    ..Three-dimensional mapping in RBBB and heart failure...
  24. ncbi Utility of exit block for identifying electrical isolation of the pulmonary veins
    Edward P Gerstenfeld
    University of Pennsylvania Medical Center, Philadelphia 19104, USA
    J Cardiovasc Electrophysiol 13:971-9. 2002
    ..We describe a new technique for guiding PV isolation, using "exit block" out of the PV after ablation as a criterion for successful isolation...
  25. ncbi Usefulness of body surface potential mapping for early identification of the intraventricular conduction disorders in young patients with chronic kidney disease
    Dorota Polak-Jonkisz
    Department of Pediatric Nephrology, Wroclaw Medical University, Wroclaw, Poland
    J Electrocardiol 42:165-71. 2009
    ..b>Body surface potential mapping (BSPM) is a noninvasive method that is useful in detecting early changes involving the heart...
  26. ncbi Localization of optimal ablation site of idiopathic ventricular tachycardia from right and left ventricular outflow tract by body surface ECG
    S Kamakura
    Division of Cardiology, Department of Internal Medicine, National Cardiovascular Center, Osaka, Japan
    Circulation 98:1525-33. 1998
    ..Idiopathic ventricular tachycardia (VT) is known to arise from the right ventricular (RV) and left ventricular outflow tracts (LVOT). However, reliable noninvasive methods to localize the optimum ablation site for VT have not been reported...
  27. ncbi Successful catheter ablation of premature ventricular contractions originating from the tricuspid annulus using a Halo-type catheter
    Takumi Yamada
    Division of Cardiovascular Disease, University of Alabama at Birmingham, 1670 University Boulevard, 1530 3rd Avenue South, Birmingham, AL 35294 0019, USA
    Europace 10:1228-9. 2008
    ..Successful catheter ablation was achieved at the ventricular site between those electrode pairs. A Halo-type catheter may be effective for mapping and catheter ablation of ventricular arrhythmias originating from the TA...
  28. ncbi High-resolution mapping around the crista terminalis during typical atrial flutter: new insights into mechanisms
    Ching Tai Tai
    Division of Cardiology, Department of Medicine, National Yang Ming University School of Medicine, Taipei Veterans General Hospital, 201 Sec 2 Shih Pai Road, Taipei, Taiwan, Republic of China
    J Cardiovasc Electrophysiol 15:406-14. 2004
    ..The aim of this study was to delineate activation patterns around the crista terminalis (CT) using high-resolution noncontact mapping...
  29. ncbi Verification of linear lesions using a noncontact multielectrode array catheter versus conventional contact mapping techniques
    B Schumacher
    Department of Cardiology, University of Bonn, Germany
    J Cardiovasc Electrophysiol 10:791-8. 1999
    ..In this study, we prospectively compared the accuracy of noncontact mapping to identify discontinuities in linear lesions and to verify a conduction block with that of conventional mapping techniques...
  30. ncbi Atrial repolarization as observable during the PQ interval
    Zenichi Ihara
    Signal Processing Institute, Swiss Federal Institute of Technology Lausanne EPFL, Switzerland
    J Electrocardiol 39:290-7. 2006
    ..We aimed to study the involvement of atrial repolarization in body surface potentials...
  31. ncbi Integration of three-dimensional left atrial magnetic resonance images into a real-time electroanatomic mapping system: validation of a registration method
    Emanuele Bertaglia
    Dipartimento di Cardiologia, Ospedale Civile di Mirano, Venice, Italy
    Pacing Clin Electrophysiol 31:273-82. 2008
    ..We assessed the accuracy of a simplified method of superimposing 3D MR left atrial images on real-time left atrial electroanatomic maps (registration)...
  32. ncbi Ablation of electrograms with an isolated, delayed component as treatment of unmappable monomorphic ventricular tachycardias in patients with structural heart disease
    Angel Arenal
    Department of Cardiology, Hospital General Universitario Gregorio Maranon, Madrid, Spain
    J Am Coll Cardiol 41:81-92. 2003
    ..We sought to evaluate the feasibility of identifying and ablating the substrate of unmappable ventricular tachycardia (VT)...
  33. ncbi Mapping of ventricular repolarization potentials in patients with arrhythmogenic right ventricular dysplasia: principal component analysis of the ST-T waves
    L De Ambroggi
    Division of Cardiology, Ospedale Clinicizzato San Donato, University of Milan, Italy
    Circulation 96:4314-8. 1997
    ....
  34. ncbi Ventricular tachycardias arising from the aortic sinus of valsalva: an under-recognized variant of left outflow tract ventricular tachycardia
    L Kanagaratnam
    Department of Cardiology, Cleveland Clinic Foundation, Ohio 44195, USA
    J Am Coll Cardiol 37:1408-14. 2001
    ..6 months. CONCLUSIONS: Normal heart VT with left bundle branch block, inferior axis and early precordial transition can be ablated in the majority of patients from either the left or the noncoronary aortic sinus of Valsalva...
  35. ncbi Characterization of endocardial electrophysiological substrate in patients with nonischemic cardiomyopathy and monomorphic ventricular tachycardia
    Henry H Hsia
    Cardiovascular Division, Hospital of University of Pennsylvania, 9 Founders, 3400 Spruce St, Philadelphia, PA 19104, USA
    Circulation 108:704-10. 2003
    ....
  36. ncbi Imaging dispersion of myocardial repolarization, I: comparison of body-surface and epicardial measures
    J E Burnes
    Cardiac Bioelectricity Research and Training Center, Department of Biomedical Engineering, Cleveland, Ohio, USA
    Circulation 104:1299-305. 2001
    ..In contrast, measures based on epicardial electrograms (ARI or epicardial QRST integral maps) provide physiologically relevant information about myocardial repolarization and can locate regions of increased dispersion...
  37. ncbi Body-surface QRST integral mapping. Arrhythmogenic righ ventricular dysplasia versus idiopathic right ventricular tachycardia
    H A Peeters
    Department of Cardiology, University Hospital Utrecht, The
    Circulation 95:2668-76. 1997
    ..This study was carried out to determine whether body-surface QRST integral mapping can differentiate patients with ARVD from patients with IRVT...
  38. ncbi Value of magnetocardiographic QRST integral maps in the identification of patients at risk of ventricular arrhythmias
    R Hren
    Physikalisch Technische Bundesanstalt, Universitatsklinikum Benjamin Franklin, Freie Universitat, Berlin, Germany
    Pacing Clin Electrophysiol 22:1292-304. 1999
    ..This finding is in agreement with earlier studies that used body surface potential mapping and suggests that magneticfield mapping may also be a useful diagnostic tool for risk analysis.
  39. ncbi Catheter ablation of ventricular tachycardia in remote myocardial infarction: substrate description guiding placement of individual linear lesions targeting noninducibility
    Hans Kottkamp
    Department of Electrophysiology Clinic of Cardiology, University of Leipzig Heart Center, Struempellstrasse 39, D 04289 Leipzig, Germany
    J Cardiovasc Electrophysiol 14:675-81. 2003
    ....
  40. ncbi Characteristics of virtual unipolar electrograms for detecting isthmus block during radiofrequency ablation of typical atrial flutter
    Yenn Jiang Lin
    Division of Cardiology, Department of Medicine, National Yang Ming University School of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    J Am Coll Cardiol 43:2300-4. 2004
    ....
  41. pmc Variable left ventricular activation pattern in patients with heart failure and left bundle branch block
    J W H Fung
    Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, SAR, China
    Heart 90:17-9. 2004
    ..To determine the left ventricular (LV) activation pattern in patients with chronic heart failure and left bundle branch block (LBBB) on ECG...
  42. ncbi Variable patterns of septal activation in patients with left bundle branch block and heart failure
    Luz Maria Rodriguez
    Department of Cardiology, Academic Hospital Maastricht, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands
    J Cardiovasc Electrophysiol 14:135-41. 2003
    ..Little is known about the septal activation pattern in patients with heart failure and left bundle branch block (LBBB-HF)...
  43. ncbi Substrate-modification using electroanatomical mapping in sinus rhythm to treat ventricular tachycardia in patients with ischemic cardiomyopathy
    T Deneke
    Medizinische Klinik II Kardiologie, Bergmannsheil Bochum Universitätsklinik, Burkle de la Camp Platz 1, 44789 Bochum, Germany
    Z Kardiol 94:453-60. 2005
    ..The treatment especially of frequent ischemic VT remains a challenge for medical and catheter ablation procedures. We evaluated the efficacy of a substrate-based procedure to eliminate clinical VTs in this patient collective...
  44. ncbi Upper turnover portion of the reentry circuit for typical and reverse typical atrial flutter
    Koji Fukuzawa
    Department of Internal Medicine, Division of Cardiovascular Medicine, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
    Pacing Clin Electrophysiol 31:1160-7. 2008
    ..The posteromedial right atrium (PMRA) forms a block line during typical atrial flutter (AFL). However, whether upper turnover portion exists at the anterior or posterior superior vena cava (SVC) has not been determined...
  45. ncbi Clinical use of body surface potential mapping in cardiac arrhythmias
    Luigi De Ambroggi
    Department of Cardiology, IRCCS Policlinico San Donato, University of Milan, Italy
    Anadolu Kardiyol Derg 7:8-10. 2007
    ....
  46. ncbi The impact of image integration on catheter ablation of atrial fibrillation using electroanatomic mapping: a prospective randomized study
    Peter M Kistler
    Department of Cardiology, St Bartholomew s Hospital, London EC1A 7BE, UK
    Eur Heart J 29:3029-36. 2008
    ..The aim of this randomized study was to determine the impact of computed tomographic (CT) integration into an electroanatomic mapping (EAM) system on clinical outcome in patients undergoing catheter ablation for atrial fibrillation (AF)...
  47. ncbi Organized left atrial tachyarrhythmia during stepwise linear ablation for atrial fibrillation
    Lihui Zheng
    Clinical EP Laboratory and Arrhythmia Center, Fuwai Hospital and Cardiovascular Institute, Peking Union Medical College PUMC Chinese Academy of Medical Sciences CAMS, Beijing, China
    J Cardiovasc Electrophysiol 20:499-506. 2009
    ..This study attempted to delineate the mechanism of organized left atrial tachyarrhythmia (AT) during stepwise linear ablation for atrial fibrillation (AF) using noncontact mapping...
  48. ncbi Strategies for epicardial mapping and ablation of ventricular tachycardia
    Usha Tedrow
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    J Cardiovasc Electrophysiol 20:710-3. 2009
    ..Potential risks include risk of injury to an epicardial coronary artery, the phrenic nerve, subdiaphragmatic vessels, and right ventricle. We describe the indications for and approach to catheter ablation of VT for the pericardial space...
  49. ncbi Atrial macroreentry tachycardia in patients without obvious structural heart disease or previous cardiac surgical or catheter intervention: characterization of arrhythmogenic substrates, reentry circuits, and results of catheter ablation
    Martin Fiala
    Department of Cardiology, Heart Center, Hospital Podlesí a s, Trinec, Czech Republic
    J Cardiovasc Electrophysiol 18:824-32. 2007
    ..Atrial macroreentry tachycardia (AMRT) in patients without obvious structural heart disease or previous surgical or catheter intervention has not been characterized in detail...
  50. ncbi Body surface Laplacian mapping of atrial depolarization in healthy human subjects
    J Lian
    Department of Bioengineering, University of Illinois at Chicago, USA
    Med Biol Eng Comput 40:650-9. 2002
    ..The above findings may be directly related to the underlying activation sequence during atrial depolarization in healthy subjects, suggesting the potential clinical applications of the Laplacian ECG technique...
  51. ncbi Statistical and deterministic approaches to designing transformations of electrocardiographic leads
    B Milan Horacek
    Faculty of Medicine of Dalhousie University, Halifax, Nova Scotia, Canada
    J Electrocardiol 35:41-52. 2002
    ....
  52. ncbi Early detection and diagnosis of acute myocardial infarction: the potential for improved care with next-generation, user-friendly electrocardiographic body surface mapping
    Cedric Lefebvre
    Department of Emergency Medicine, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    Am J Emerg Med 25:1063-72. 2007
    ....
  53. ncbi A simple algorithm for defining the mechanism and the chamber of origin in atrial tachycardias
    Tchavdar Nikolov Shalganov
    Department of Clinical Cardiac Electrophysiology and Cardiac Pacing, Gottsegen Gyorgy Hungarian Institute of Cardiology, H 1096 Budapest, Hungary
    J Electrocardiol 39:369-76. 2006
    ..Although macroreentrant atrial tachycardia (MRAT) and focal atrial tachycardia (FAT) can be successfully cured by catheter ablation, the proper diagnosis and treatment of these arrhythmias can still be challenging...
  54. ncbi Comparison of the 80-lead body surface map to physician and to 12-lead electrocardiogram in detection of acute myocardial infarction
    Anthony J J McClelland
    Regional Medical Cardiology Centre, Royal Victoria Hospital, Northern Ireland, Belfast, United Kingdom
    Am J Cardiol 92:252-7. 2003
    ..There was no significant difference in specificity. Thus, the BSM algorithm improves detection of AMI compared with the 12-lead ECG algorithm or physician's 12-lead ECG interpretation...
  55. ncbi Recording locations in multichannel magnetocardiography and body surface potential mapping sensitive for regional exercise-induced myocardial ischemia
    H Hanninen
    Helsinki University Central Hospital, Division of Cardiology, Cardiovascular Laboratory, Finland
    Basic Res Cardiol 96:405-14. 2001
    This study aimed to identify the optimal locations in multichannel magnetocardiography (MCG) and body surface potential mapping (BSPM) to detect exercise-induced myocardial ischemia.
  56. ncbi Solving the cardiac bidomain equations for discontinuous conductivities
    Travis M Austin
    Bioengineering Institute, The University of Auckland, Private Bag 92019, Auckland 1001, New Zealand
    IEEE Trans Biomed Eng 53:1265-72. 2006
    ..Also, for the problems examined, it will be shown that a direct usage of conventional multigrid leads to faster simulations than an indirect usage of conventional multigrid as a preconditioner unless there are sharp discontinuities...
  57. ncbi Idiopathic left ventricular tachycardia: assessment and treatment
    Akihiko Nogami
    Clinical Electrophysiology Laboratory and Pacemaker Service, Yokohama Rosai Hospital, Yokohama, Kanagawa, Japan
    Card Electrophysiol Rev 6:448-57. 2002
    ..Recognition of the characteristics of the various forms of this group of arrhythmias should facilitate appropriate diagnosis and therapy...
  58. ncbi Mapping for ventricular tachycardia
    Sanjay Dixit
    Section of Cardiac Electrophysiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Card Electrophysiol Rev 6:436-41. 2002
    ..Other recent advances such as percutaneous closed chest epicardial mapping technique and cooled tip ablation catheter technology have the potential to enhance mapping and successful ablation of VT...
  59. ncbi Body surface potential mapping: historical background, present possibilities, diagnostic challenges
    Mihály Medvegy
    Medical and Cardiovascular Department, Faculty of Health Sciences, Semmelweis University, Szabolcs 35, Budapest, Hungary 1135
    Ann Noninvasive Electrocardiol 7:139-51. 2002
  60. ncbi Electrocardiographic body surface mapping: potential tool for the detection of transient myocardial ischemia in the 21st century?
    Monique R Robinson
    Wessex Cardiothoracic Unit, Southampton General Hospital, Southampton, UK
    Ann Noninvasive Electrocardiol 14:201-10. 2009
    ..Research is ongoing to determine the full extent of its utility...
  61. ncbi How to determine and assess endpoints for left atrial ablation
    Kazuhiro Satomi
    II Med Abteilung, Asklepios Klinik St Georg, Hamburg, Germany
    Heart Rhythm 4:374-80. 2007
  62. ncbi Left septal atrial flutter: electrophysiology, anatomy, and results of ablation
    Nassir F Marrouche
    Section of Pacing and Electrophysiology, Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Circulation 109:2440-7. 2004
    ..We describe the clinical and electrophysiological characteristics of a novel macroreentrant form of left atrial flutter circuit...
  63. ncbi Coronary sinus-ventricular accessory connections producing posteroseptal and left posterior accessory pathways: incidence and electrophysiological identification
    Yingxian Sun
    Cardiac Arrhythmia Research Institute and Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City 73104, USA
    Circulation 106:1362-7. 2002
    ..The purpose of the present study was to use CS angiography and mapping to define and determine the incidence of CSAPs and determine the relationship to CS anatomy...
  64. ncbi Atrial macroreentry involving the myocardium of the coronary sinus: a unique mechanism for atypical flutter
    J E Olgin
    Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis 46202, USA
    J Cardiovasc Electrophysiol 9:1094-9. 1998
    ..Successful ablation of the rhythm was accomplished by a circumferential radiofrequency application within the coronary sinus...
  65. ncbi Simplified algorithm for localization of atrial macroreentrant tachycardias: keep it simple and short
    Isabel Deisenhofer
    Heart Rhythm 3:524-5. 2006
  66. ncbi Surface electrocardiographic characteristics of right and left atrial flutter
    Andres Bochoeyer
    Cardiovascular Research Institute and Section of Cardiac Electrophysiology, University of California, San Francisco 94143 1354, USA
    Circulation 108:60-6. 2003
    ..There is little information about the surface expression of non-cavotricuspid isthmus (CTI)-dependent right atrial (RA) or left atrial (LA) flutter circuits...
  67. ncbi Remote magnetic navigation for mapping and ablating right ventricular outflow tract tachycardia
    Andrew S Thornton
    Department of Clinical Electrophysiology, Thoraxcentre, Erasmus Medical Centre, Rotterdam, The Netherlands
    Heart Rhythm 3:691-6. 2006
    ..Navigation, mapping, and ablation in the right ventricular outflow tract (RVOT) can be difficult. Catheter navigation using external magnetic fields may allow more accurate mapping and ablation...
  68. ncbi Body surface potential mapping investigating the ventricular activation patterns in the cardiac resynchronization of patients with left bundle-branch block and heart failure
    Carlos Alberto Pastore
    Heart Institute InCor of the University of Sao Paulo Medical School, Brazil
    J Electrocardiol 39:93-102. 2006
    b>Body surface potential mapping assessed mean cardiac electrical activation times displayed by isochronal maps in the right ventricle (RV; right ventricle mean activation time [mRV]), anterior septal area (anterior septal area mean ..
  69. pmc Body surface mapping improves early diagnosis of acute myocardial infarction in patients with chest pain and left bundle branch block
    S J Maynard
    Regional Medical Cardiology Centre, Royal Victoria Hospital, Belfast, Northern Ireland, UK
    Heart 89:998-1002. 2003
    ....
  70. ncbi Corrected body surface potential mapping
    Gerhard Krenzke
    Deutsches Herzzentrum Berlin, Berlin, Germany
    Biomed Tech (Berl) 52:37-42. 2007
    In the method for body surface potential mapping described here, the influence of thorax shape on measured ECG values is corrected...
  71. ncbi Reentry within the cavotricuspid isthmus: an isthmus dependent circuit
    Yanfei Yang
    Department of Medicine Cardiac Electrophysiology Section, University of California, San Francisco, CA 94143, USA
    Pacing Clin Electrophysiol 28:808-18. 2005
    ..We describe a new cavotricuspid isthmus (CTI) circuit...
  72. ncbi The optimized V-V interval determined by interventricular conduction times versus invasive measurement by LVdP/dtMAX
    Berry M van Gelder
    Department of Cardiology, Catharina Hospital, Eindhoven, The Netherlands
    J Cardiovasc Electrophysiol 19:939-44. 2008
    ..We compared the calculated optimal V-V interval derived from intracardiac electrograms (IEGM) with the optimized V-V interval determined by invasive measurement of LVdP/dt(MAX)...
  73. ncbi Image integration using NavX Fusion: initial experience and validation
    Anthony G Brooks
    Cardiovascular Research Centre, Department of Cardiology, Royal Adelaide Hospital and Disciplines of Medicine and Physiology, University of Adelaide, Adelaide, South Australia
    Heart Rhythm 5:526-35. 2008
    ..NavX Fusion software aims to mold the virtual anatomy to the patient's computed tomography (CT) image; however, the accuracy and clinical usefulness of this system have not been reported...
  74. ncbi Electroanatomic mapping of entrained and exit zones in patients with repaired congenital heart disease and intra-atrial reentrant tachycardia
    J K Triedman
    Department of Cardiology, Children s Hospital, Boston, MA 02115, USA
    Circulation 103:2060-5. 2001
    ..Characterization of reentrant circuits and targeting ablation sites remains difficult for intra-atrial reentrant tachycardias (IART) in congenital heart disease (CHD)...
  75. ncbi Gross structure of the atriums: more than an anatomic curiosity?
    Siew Yen Ho
    Faculty of Medicine, National Heart and Lung Institute, Imperial College of Science, Technology and Medicine, and Royal Brompton and Harefield NHS Trust, London yen ho vaic ac uk
    Pacing Clin Electrophysiol 25:342-50. 2002
    ..The structure of the atrium is more than an anatomic curiosity. It has practical implicationsfor mapping and interventional procedures...
  76. ncbi ST-T integral and T-wave amplitude in detection of exercise-induced myocardial ischemia evaluated with body surface potential mapping
    Helena Hänninen
    Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland
    J Electrocardiol 36:89-98. 2003
    b>Body surface potential mapping is superior to 12-lead electrocardiogram in detection of acute and old myocardial infarctions...
  77. ncbi Characterization of reentrant circuits in left atrial macroreentrant tachycardia: critical isthmus block can prevent atrial tachycardia recurrence
    Feifan Ouyang
    II Med Abteilung, Allgemeines Krankenhaus St Georg, Hamburg, Germany
    Circulation 105:1934-42. 2002
    ..Left atrial macroreentrant tachycardia (LAMRT) has not been characterized in detail...
  78. ncbi Atypical atrial flutter originating in the right atrial free wall
    J G Kall
    University of Chicago, Chicago, Illinois, USA
    Circulation 101:270-9. 2000
    ..Data characterizing the various forms of atypical atrial flutter in humans are limited...
  79. ncbi Supplemented standard 12-lead electrocardiogram for optimal diagnosis and reconstruction of significant body surface map patterns
    Fred Kornreich
    Unit of Cardiovascular Research and Engineering, School of Medicine, Free University of Brussels VUB, Brussels, Belgium
    J Electrocardiol 41:251-6. 2008
    ..Combining these 2 ideas, namely, addition of optimal leads and estimation of BSPMs improves performance even more...
  80. ncbi Validation of computed tomography image integration into the EnSite NavX mapping system to perform catheter ablation of atrial fibrillation
    Laura Richmond
    Department of Cardiology, St Bartholomew s Hospital and Queen Mary College, University of London, UK
    J Cardiovasc Electrophysiol 19:821-7. 2008
    ..We describe the integration of a CT image into the EnSite NavX System with Fusion and its validation in patients undergoing atrial fibrillation (AF) or left atrial tachycardia (AT) catheter ablation...
  81. ncbi Pulmonary vein ablation using the LocaLisa nonfluoroscopic mapping system
    Rukshen Weerasooriya
    Hopital Cardiologique du Haut Leveque, Bordeaux Pessac, France
    J Cardiovasc Electrophysiol 14:112. 2003
  82. ncbi How many electrodes and where? A "poldermodel" for electrocardiography
    Jan A Kors
    Department of Medical Informatics, Faculty of Medicine and Health Sciences, Erasmus University, Rotterdam, The Netherlands
    J Electrocardiol 35:7-12. 2002
    ..This approach also obviates the need to determine the precise location of V(4) electrode, which may be difficult in women...
  83. ncbi Beyond the 12 lead: review of the use of additional leads for the early electrocardiographic diagnosis of acute myocardial infarction
    Simon D Carley
    Wythenshawe Hospital, Manchester, England
    Emerg Med (Fremantle) 15:143-54. 2003
    ..This review demonstrates the need for additional leads in the acute setting and makes recommendations about the utility of using additional leads in the ED...
  84. ncbi Feasibility study of endocardial mapping of ganglionated plexuses during catheter ablation of atrial fibrillation
    Robert Lemery
    Division of Cardiology, University of Ottawa Heart Institute, Ontario, Canada
    Heart Rhythm 3:387-96. 2006
    ..Numerous reports have demonstrated an association between autonomic tone and atrial fibrillation (AF). Pulmonary vein (PV) denervation during catheter ablation of AF has been shown to significantly reduce recurrence of AF...
  85. ncbi Ventricular tachycardia duration and form are associated with electrical discontinuities bounding the core of the reentrant circuit
    Edward J Ciaccio
    Department of Pharmacology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Cardiovasc Electrophysiol 16:646-54. 2005
    ..Successful prediction of reentrant ventricular tachycardia duration and form from sinus-rhythm electrogram signals in canine hearts is relevant to clinical studies, to potentially improve catheter ablation treatment during EP study...
  86. ncbi Biatrial and three-dimensional mapping of spontaneous atrial arrhythmias in patients with refractory atrial fibrillation
    Sanjeev Saksena
    Electrophysiology Research Foundation, Warren, New Jersey, USA
    J Cardiovasc Electrophysiol 16:494-504. 2005
    ..We hypothesized that these two techniques would provide novel information on triggers, initiation, and evolution of spontaneous AF and permit study of different AF populations...
  87. ncbi Global and local dispersion of ventricular repolarization: endocardial monophasic action potential mapping in swine and humans by using an electro-anatomical mapping system
    Ole Kongstad
    Department of Cardiology, University Hospital, Lund, Sweden
    J Electrocardiol 35:159-67. 2002
    ..In conclusion, global DVR is poorly estimated from MAP recordings from a few adjacent or remote sites, suggesting the importance of obtaining global information in evaluating DVR...
  88. ncbi Electrogram polarity reversal as an additional indicator of breakthroughs from the left atrium to the pulmonary veins
    Teiichi Yamane
    Hopital Cardiologique du Haut Leveque, Bordeaux Pessac, France
    J Am Coll Cardiol 39:1337-44. 2002
    ..We assessed the anatomical distribution and electrogram characteristics of breakthrough from the left atrium (LA) to the pulmonary veins (PVs)...
  89. ncbi Non-contact mapping to guide catheter ablation of untolerated ventricular tachycardia
    P Della Bella
    Institute of Cardiology, University of Milan, IRCCS, Centro Cardiologico Fonazione I Monzino, Milan
    Eur Heart J 23:742-52. 2002
    ....
  90. ncbi Target sites for catheter ablation of unmappable ventricular tachycardia during sinus rhythm
    Etienne Delacretaz
    Heart Rhythm 3:513-5. 2006
  91. ncbi The JT-area indicates dispersion of repolarization in dogs with atrioventricular block
    Jurren M van Opstal
    Department of Cardiology, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands
    J Interv Card Electrophysiol 6:113-20. 2002
    ..The purpose of this study was to correlate known changes in Delta MAPD with the planimetric total area of the T-wave on the surface ECG (integral of J-T, mVx ms)...
  92. ncbi Entrainment mapping for rapid distinction of left and right atrial tachycardias
    Hidekazu Miyazaki
    Cardiovascular Division, Department of Internal Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Heart Rhythm 3:516-23. 2006
    ..Distinguishing left from right atrial tachycardia is a critical step for guiding ablation...
  93. ncbi Ablation of focal atrial arrhythmia in patients with congenital heart defects after surgery: role of circumscribed areas with heterogeneous conduction
    Natasja M S de Groot
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    Heart Rhythm 3:526-35. 2006
    ....
  94. ncbi Left atrial pacemaker dominance after catheter ablation of atrial fibrillation
    Prashanthan Sanders
    Hôpital Cardologique du Haut Lévêque and the Université Victor Segalen Bordeaux 2, Bordeaux, France
    J Cardiovasc Electrophysiol 15:1324-7. 2004
    ..We report a case of left atrial dominant rhythm demonstrated by electroanatomic mapping. The rhythm occurred after radiofrequency catheter ablation in a patient with persistent atrial fibrillation and structural heart disease...
  95. ncbi [Value of mapping in surgical treatment of ventricular tachycardia]
    D Lacroix
    Service de cardiologie A, CHRU de Lille
    Arch Mal Coeur Vaiss 89:109-13. 1996
    ..The only really curative approach because of the limitations of catheter ablation, this surgery is a complementary method to implantable defibrillators in the management of post-infarction ventricular tachycardia...
  96. ncbi Atrial tachycardia with widely-split P waves may mimic a distinct faster atrial tachycardia with half the cycle length of the actual P-P interval
    Takumi Yamada
    Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL 35294 0019, USA
    Circ J 72:1381-4. 2008
    ..The focal AT with inter- and intra-atrial conduction block exhibited widely-split P waves misinterpreted as a distinct AT...
  97. ncbi Rectification of the background potassium current: a determinant of rotor dynamics in ventricular fibrillation
    F H Samie
    SUNY Upstate Medical University, Syracuse, NY, USA
    Circ Res 89:1216-23. 2001
    ....
  98. ncbi Effect of pulmonary vein isolation on the left-to-right atrial dominant frequency gradient in human atrial fibrillation
    Sorin Lazar
    Department of Medicine, Electrophysiology Division, University of Pennsylvania Health System, Philadelphia, 19104, USA
    Heart Rhythm 3:889-95. 2006
    ..One possible mechanism of the left-to-right dominant frequency gradient involves the role of the pulmonary veins (PVs) in AF maintenance...
  99. ncbi Mechanisms of wave fractionation at boundaries of high-frequency excitation in the posterior left atrium of the isolated sheep heart during atrial fibrillation
    Jerome Kalifa
    Institute for Cardiovascular Research, Department of Pharmacology, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Circulation 113:626-33. 2006
    ..We tested the hypothesis that highly periodic electric waves emerging from AF sources at or near the PLA give rise to the most fractionated activity in adjacent locations...
  100. ncbi Characteristics of cavotricuspid isthmus-dependent atrial flutter after left atrial ablation of atrial fibrillation
    Aman Chugh
    Division of Cardiology, University of Michigan Hospitals, Ann Arbor, MI, USA
    Circulation 113:609-15. 2006
    ..The effects of left atrial (LA) ablation on the characteristics of CTI-dependent flutter have not been described...
  101. ncbi Null mutation of connexin43 causes slow propagation of ventricular activation in the late stages of mouse embryonic development
    D Vaidya
    Department of Pharmacology, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Circ Res 88:1196-202. 2001
    ..This study demonstrates the contribution of Cx43 to the electrical function of the developing mouse heart and the essential role of this gene in maintaining heart rhythm in postnatal life...

Research Grants39

  1. High-Speed, Depth-Resolved Images of Cardiac physiology
    Guy Salama; Fiscal Year: 2007
    ..We focus here on the heart because therein lie salient problems that are ready to be addressed by this new technology. However, the wide range of possible applications may lead to the commercialization of this new technology. ..
  2. OPTO-ELECTRIC MAPPING OF ACTION POTENTIALS
    Igor R Efimov; Fiscal Year: 2013
    ..However, this method provides only electrograms and not the action potentials. Moreover, body surface potential mapping modalities thus far cannot recreate endocardial electrograms, which requires invasive transvenous ..
  3. COMPARISON OF ELECTROPHYSIOLOGIC STUDY TO ECG MONITORING
    Jay Mason; Fiscal Year: 1992
    ..of the influence of left ventricular dysfunction upon antiarrhythmic drug efficacy; and use of body surface potential mapping to identify arrhythmia vulnerability...
  4. MECHANISMS FOR MAINTENANCE OF VENTRICULAR FIBRILLATION
    Jack Rogers; Fiscal Year: 2006
    ..This project will develop single anld multisite pacing circuits and evaluate their performance using panoramic optical mapping of isolated perfused swine hearts. ..
  5. Visualizing the Substrate for Sudden Cardiac Death
    Vivek Reddy; Fiscal Year: 2006
    ..abstract_text> ..
  6. Substrate Mapping & Ablation of Ventricular Tachycardia
    Vivek Reddy; Fiscal Year: 2006
    ..abstract_text> ..
  7. High Resolution EEG Source Imaging: Validation Study
    Bin He; Fiscal Year: 2005
    ..The studies addressed in this application may establish CIT as a clinically useful tool aiding neurosurgical planning in epilepsy patients. ..
  8. The Pathophysiology of T-wave Alternans
    Sanjiv Narayan; Fiscal Year: 2005
    ..This structured approach will ensure the successful completion of this project and, in this way, the development of the applicant into an independent clinician-investigator. ..
  9. CARDIAC EXCITATION AND ARRHYTHMIAS
    Yoram Rudy; Fiscal Year: 2008
    ..4) To study the properties and repolarization-dependent mechanisms of arrhythmias in the remodeled myocardium post myocardial infarction. ..
  10. INVERSE AND FORWARD PROBLEMS IN ELECTROCARDIOGRAPHY
    Yoram Rudy; Fiscal Year: 2007
    ..abstract_text> ..
  11. NUMERICAL SIMULATION OF CARDIAC ELECTROPHYSIOLOGY
    Bradley Roth; Fiscal Year: 2005
    ..Each hypothesis is motivated by experimental data, and the goal of the theoretical simulations is to interpret these data. ..
  12. Magnetoacoustic Tomography with Magnetic Induction
    Bin He; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  13. A Computational Approach for 3D Brain Source Imaging
    Bin He; Fiscal Year: 2010
    ..The availability of a noninvasive imaging technology to identify and image the epileptogenic foci would benefit numerous patients suffering from epilepsy and the healthcare system. ..
  14. Three Dimensional Electrocardiographic Imaging
    Bin He; Fiscal Year: 2010
    ....
  15. Personal Electrocardiographic Expert System
    Vladimir Shusterman; Fiscal Year: 2007
    ..Safety and regulatory testing will be completed, and a 51O K application will be submitted to the FDA. [unreadable] [unreadable]..
  16. Nanosecond megavolt pulse technology for cardiac stimulation and defibrillation
    Miguel Valderrabano; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  17. 3D Noninvasive Temperature Estimation with Ultrasound
    R Arthur; Fiscal Year: 2007
    ....
  18. ULTRASOUND-INDUCED DRUG DELIVERY THROUGH THE BLOOD-BRAIN BARRIER
    Elisa Konofagou; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
  19. COMPUTER ASSISTED MAPPING OF VENTRICULAR FIBRILLATION
    Raymond Ideker; Fiscal Year: 2009
    ..This understanding will give us new information needed to develop therapies to counteract these mechanisms of VF maintenance to prevent sudden cardiac arrest, one of the leading health problems in the world today. ..
  20. AGE-RELATED CHANGE IN TRIGEMINAL GANGLION EXCITABILITY
    Thomas Baumann; Fiscal Year: 2003
    ..The experiments will contribute to a better understanding of the factors which may contribute to the age-related increase in the incidence of trigeminal neuralgia and other types of oro-facial neuropathic pain. ..
  21. VENTRICULAR FIBRILLATION AND ITS ALTERATION BY PACING
    Raymond E Ideker; Fiscal Year: 2010
    ..We will test the hypotheses that pacing from the dominant domain (1) captures the maximum amount of tissue during VF and (2) halts the most organized types of VF. ..
  22. REENTRANT ACTIVITY IN CULTURED CARDIAC CELL MONOLAYERS
    Leslie Tung; Fiscal Year: 2009
    ..These aims exploit the properties of the cultured cell monolayer as a well-controlled, versatile and quantitative experimental model for basic studies of clinically important, reentry-based arrhythmias. ..
  23. Electrical Control of Reentrant Spiral Waves in Cardiac Tissue
    Leslie Tung; Fiscal Year: 2007
    ..The successful use of low energy counterchecks can avoid the pain and psychological trauma of present day high energy therapy. [unreadable] [unreadable] [unreadable]..
  24. Bioreactor for Stem Cell Tissue Engineering
    Leslie Tung; Fiscal Year: 2002
    ..The ability to expand and differentiate stem cells with this technology could provide a virtually unlimited source of tissue for treatment of disease and injury. ..
  25. NEUROPHYSIOLOGY OF TRIGEMINAL NEURALGIA
    Thomas Baumann; Fiscal Year: 2002
    ..abstract_text> ..
  26. Noninvasive Temperature Estimation with Ultrasound
    R Arthur; Fiscal Year: 2003
    ..Because our approach exploits the inhomogeneities present in tissue, we believe that if it is successful in vitro; it holds promise for in vivo application. ..
  27. Cardiac Arrhythmia Mechanisms
    JOSE JALIFE; Fiscal Year: 2005
    ....
  28. Novel Methods for Cardiac Micro-Impedance Measurement
    Andrew Pollard; Fiscal Year: 2005
    ..abstract_text> ..
  29. Contact Fluorescence Imaging
    Leslie Tung; Fiscal Year: 2006
    ....
  30. CARDIAC MAPPING OF VENTRICULAR DEFIBRILLATION
    Raymond Ideker; Fiscal Year: 2006
    ..It is hoped that the basic knowledge gained about defibrillation mechanisms through these studies will lead to the improvement of defibrillation in patients. ..
  31. Expert Visual Guidance of Ultrasound for Telemedicine
    Florence Sheehan; Fiscal Year: 2006
    ..Specific Aim #4 is to make the guidance easily applicable to different organs. [unreadable] [unreadable]..
  32. Detection of neonatal ventricular hemorrhage using EIT
    Rosalind Sadleir; Fiscal Year: 2006
    ..These data will be analyzed to determine the best way of separating artifacts produced by shape changes and other body impedance changes from the bleeding process. ..
  33. ELECTRICAL EXCITATION OF CARDIAC MUSCLE
    Leslie Tung; Fiscal Year: 2001
    ....
  34. MECHANISMS OF REPOLARIZATION-INDUCED ARRHYTHMIAS
    Guy Salama; Fiscal Year: 2002
    ..abstract_text> ..
  35. Gender-Differences in Cardiac Repolarization/Arrhythmias
    Guy Salama; Fiscal Year: 2005
    ..abstract_text> ..
  36. A Depth-resolved Voltage Sensitive Dye Imaging System
    Elizabeth Hillman; Fiscal Year: 2007
    ..The effects of abnormal pathologies on neurovascular coupling could provide new insights for treatment and prevention. The new system could also find applications in ocular, dermal, endoscopic and tumor imaging. [unreadable] [unreadable]..
  37. Factors that Initiate Arrhythamias in Long QT Syndrome
    Guy Salama; Fiscal Year: 2006
    ..Stimulation paradigms that i) enhance DOR or ii) elicit a bradycardia followed by a tachycardia are more likely to increase the incidence of EADs or TdP. ..
  38. MINORITY PREDOCTORAL FELLOWSHIP PROGRAM
    NINITA BROWN; Fiscal Year: 2005
    ..Finally, the measurement of action potential duration within the moving ardiac wall will be used to determine the ability of a ratiometric system to decrease the motion artifact without the use of a mechanical uncoupling agent. ..