echocardiography

Summary

Summary: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.

Top Publications

  1. doi Incidence and clinical significance of left ventricular thrombus in tako-tsubo cardiomyopathy assessed with echocardiography
    D Haghi
    I Medizinische Klinik, Universitätsklinikum Mannheim 68167 Mannheim, Germany
    QJM 101:381-6. 2008
  2. ncbi Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiograph
    Roberto M Lang
    University of Chicago Hospitals, Chicago, IL, USA
    J Am Soc Echocardiogr 18:1440-63. 2005
  3. ncbi Recommendations for chamber quantification
    Roberto M Lang
    Med Klinik 2, Erlangen University, Ulmenweg 18, 91054 Erlangen, Germany
    Eur J Echocardiogr 7:79-108. 2006
  4. ncbi Obesity and the risk of heart failure
    Satish Kenchaiah
    Framingham Heart Study, Framingham, Mass 01702, USA
    N Engl J Med 347:305-13. 2002
  5. ncbi Guidelines on the management of valvular heart disease: The Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology
    Alec Vahanian
    Service de cardiologie, Hôpital Bichat AP HP, Paris, France
    Eur Heart J 28:230-68. 2007
  6. ncbi Recommendations for evaluation of the severity of native valvular regurgitation with two-dimensional and Doppler echocardiography
    William A Zoghbi
    J Am Soc Echocardiogr 16:777-802. 2003
  7. doi Assessment of myocardial mechanics using speckle tracking echocardiography: fundamentals and clinical applications
    Holly Geyer
    Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, AZ 85259, USA
    J Am Soc Echocardiogr 23:351-69; quiz 453-5. 2010
  8. ncbi Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI)
    Birgit Assmus
    Department of Molecular Cardiology, University of Frankfurt, Frankfurt, Germany
    Circulation 106:3009-17. 2002
  9. ncbi Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
    Michael A Laflamme
    Center for Cardiovascular Biology, Institute for Stem Cell and Regenerative Medicine, University of Washington, 815 Mercer Street, Seattle, WA 98109, USA
    Nat Biotechnol 25:1015-24. 2007
  10. pmc Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the task force criteria
    Frank I Marcus
    University of Arizona, Tucson, Ariz, USA
    Circulation 121:1533-41. 2010

Research Grants

  1. The role of IKK beta in cardiomyocytes at baseline and following stress
    MATTHEW PETER COGGINS; Fiscal Year: 2013
  2. JNK exacerbates ischemia/reperfusion injury in hyperglycemic subjects.
    Keith A Webster; Fiscal Year: 2010
  3. Aldosterone Action In The Brain, Hypertension and Inflammation
    ELISE PEERY GOMEZ-SANCHEZ; Fiscal Year: 2012
  4. Targeting Cell Death to Prevent Ventricular Remodeling and Heart Failure
    Abhinav Diwan; Fiscal Year: 2011
  5. JACKSON HEART STUDY
    HERMAN ALFRED TAYLOR; Fiscal Year: 2009
  6. JACKSON HEART STUDY
    Asoka Srinivasan; Fiscal Year: 2010
  7. JACKSON HEART STUDY
    Herman Taylor; Fiscal Year: 2010
  8. JACKSON HEART STUDY
    HERMAN ALFRED TAYLOR; Fiscal Year: 2009
  9. JACKSON HEART STUDY
    ASOKA S SRINIVASAN; Fiscal Year: 2013
  10. JACKSON HEART STUDY
    ASOKA S SRINIVASAN; Fiscal Year: 2011

Detail Information

Publications350 found, 100 shown here

  1. doi Incidence and clinical significance of left ventricular thrombus in tako-tsubo cardiomyopathy assessed with echocardiography
    D Haghi
    I Medizinische Klinik, Universitätsklinikum Mannheim 68167 Mannheim, Germany
    QJM 101:381-6. 2008
    ..However, current literature almost exclusively consists of isolated case reports. The aim of this study was to determine the incidence and clinical significance of LV thrombus formation in TC...
  2. ncbi Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiograph
    Roberto M Lang
    University of Chicago Hospitals, Chicago, IL, USA
    J Am Soc Echocardiogr 18:1440-63. 2005
  3. ncbi Recommendations for chamber quantification
    Roberto M Lang
    Med Klinik 2, Erlangen University, Ulmenweg 18, 91054 Erlangen, Germany
    Eur J Echocardiogr 7:79-108. 2006
    ..mass and function ranks among the most clinically important and most frequently requested tasks of echocardiography. Over the last decades, echocardiographic methods and techniques have improved and expanded dramatically, due ..
  4. ncbi Obesity and the risk of heart failure
    Satish Kenchaiah
    Framingham Heart Study, Framingham, Mass 01702, USA
    N Engl J Med 347:305-13. 2002
    ..Extreme obesity is recognized to be a risk factor for heart failure. It is unclear whether overweight and lesser degrees of obesity also pose a risk...
  5. ncbi Guidelines on the management of valvular heart disease: The Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology
    Alec Vahanian
    Service de cardiologie, Hôpital Bichat AP HP, Paris, France
    Eur Heart J 28:230-68. 2007
  6. ncbi Recommendations for evaluation of the severity of native valvular regurgitation with two-dimensional and Doppler echocardiography
    William A Zoghbi
    J Am Soc Echocardiogr 16:777-802. 2003
  7. doi Assessment of myocardial mechanics using speckle tracking echocardiography: fundamentals and clinical applications
    Holly Geyer
    Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, AZ 85259, USA
    J Am Soc Echocardiogr 23:351-69; quiz 453-5. 2010
    The authors summarize the recent developments in speckle-tracking echocardiography (STE), a relatively new technique that can be used in conjunction with two-dimensional or three-dimensional echocardiography for resolving the ..
  8. ncbi Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI)
    Birgit Assmus
    Department of Molecular Cardiology, University of Frankfurt, Frankfurt, Germany
    Circulation 106:3009-17. 2002
    ..The safety and feasibility of autologous progenitor cell transplantation in patients with ischemic heart disease is unknown...
  9. ncbi Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
    Michael A Laflamme
    Center for Cardiovascular Biology, Institute for Stem Cell and Regenerative Medicine, University of Washington, 815 Mercer Street, Seattle, WA 98109, USA
    Nat Biotechnol 25:1015-24. 2007
    ..The ability of hES cell-derived cardiomyocytes to partially remuscularize myocardial infarcts and attenuate heart failure encourages their study under conditions that closely match human disease...
  10. pmc Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the task force criteria
    Frank I Marcus
    University of Arizona, Tucson, Ariz, USA
    Circulation 121:1533-41. 2010
    ..Consequently, the 1994 criteria were highly specific but lacked sensitivity for early and familial disease...
  11. ncbi Epicardial fat from echocardiography: a new method for visceral adipose tissue prediction
    Gianluca Iacobellis
    Endocrinology, Department of Clinical Sciences, La Sapienza University, Rome Italy
    Obes Res 11:304-10. 2003
    To validate transthoracic echocardiography as an easy and reliable imaging method for visceral adipose tissue (VAT) prediction. VAT is recognized as an important indicator of high cardiovascular and metabolic risk...
  12. ncbi Speckle-tracking echocardiography: a new technique for assessing myocardial function
    Sergio Mondillo
    Department of Cardiovascular Diseases, University of Sienna, Siena, Italy
    J Ultrasound Med 30:71-83. 2011
    Speckle-tracking echocardiography has recently emerged as a quantitative ultrasound technique for accurately evaluating myocardial function by analyzing the motion of speckles identified on routine 2-dimensional sonograms...
  13. ncbi Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association
    Jane W Newburger
    Pediatrics 114:1708-33. 2004
    ..Coronary artery aneurysms or ectasia develop in approximately 15% to 25% of untreated children and may lead to ischemic heart disease or sudden death...
  14. ncbi American Society of Echocardiography recommendations for use of echocardiography in clinical trials
    John S Gottdiener
    University of Maryland Hospital, Baltimore, USA
    J Am Soc Echocardiogr 17:1086-119. 2004
  15. pmc Adiponectin-mediated modulation of hypertrophic signals in the heart
    Rei Shibata
    Molecular Cardiology Whitaker Cardiovascular Institute, Boston University School of Medicine, 715 Albany Street, W611, Boston, Massachusetts 02118, USA
    Nat Med 10:1384-9. 2004
    ..Adiponectin may have utility for the treatment of hypertrophic cardiomyopathy associated with diabetes and other obesity-related diseases...
  16. ncbi Impact of diabetes on cardiac structure and function: the strong heart study
    R B Devereux
    New York Hospital Cornell Medical Center, New York, USA
    Circulation 101:2271-6. 2000
    ..Whether diabetes mellitus (DM) adversely affects left ventricular (LV) structure and function independently of increases in body mass index (BMI) and blood pressure is controversial...
  17. doi Detection of pulmonary hypertension with multidetector CT and echocardiography alone and in combination
    Anand Devaraj
    Department of Radiology, Royal Brompton Hospital, Sydney Street, London, SW3 6NP, England
    Radiology 254:609-16. 2010
    ..To test the reliability of potentially new computed tomographic (CT) indicators of pulmonary hypertension (PH) and to establish whether a combination of CT and echocardiographic measurements was more predictive of PH than either test alone...
  18. doi Subclinical left ventricular dysfunction in asymptomatic diabetic patients assessed by two-dimensional speckle tracking echocardiography: correlation with diabetic duration
    Hiromi Nakai
    Second Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan
    Eur J Echocardiogr 10:926-32. 2009
    ..Subclinical left ventricular (LV) systolic dysfunction may be identified by a reduction in longitudinal function, which can be assessed using 2D speckle tracking echocardiography (STE).
  19. ncbi Noninvasive myocardial strain measurement by speckle tracking echocardiography: validation against sonomicrometry and tagged magnetic resonance imaging
    Brage H Amundsen
    Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway
    J Am Coll Cardiol 47:789-93. 2006
    The aim of this study was to validate speckle tracking echocardiography (STE) as a method for angle-independent measurement of regional myocardial strain, using sonomicrometry and magnetic resonance imaging (MRI) tagging as reference ..
  20. ncbi Echocardiographic epicardial adipose tissue is related to anthropometric and clinical parameters of metabolic syndrome: a new indicator of cardiovascular risk
    Gianluca Iacobellis
    Endocrinology, Department of Clinical Sciences, La Sapienza University, 00161 Rome, Italy
    J Clin Endocrinol Metab 88:5163-8. 2003
    ..387; P = 0.03) were the strongest independent variables correlated with epicardial adipose tissue. Echocardiographic epicardial adipose tissue could be applied as an easy and reliable imaging indicator of VAT and cardiovascular risk...
  21. doi Diabetic cardiomyopathy: insights into pathogenesis, diagnostic challenges, and therapeutic options
    Ashish Aneja
    The Mount Sinai Cardiovascular Institute, New York, NY 10029, USA
    Am J Med 121:748-57. 2008
    ..Although glycemic control and early administration of neurohormonal antagonists remain the cornerstones of therapeutic approaches, newer treatment targets are currently being explored...
  22. ncbi Prognostic value of echocardiographically assessed right ventricular dysfunction in patients with pulmonary embolism
    Marije Ten Wolde
    Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Arch Intern Med 164:1685-9. 2004
    ..However, the prognostic value of right ventricular dysfunction in these patients is still unclear...
  23. ncbi Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young,
    Larry M Baddour
    Circulation 111:e394-434. 2005
    ..The continuing evolution of antimicrobial resistance among common pathogens that cause infective endocarditis creates additional therapeutic issues for physicians to manage in this potentially life-threatening illness...
  24. ncbi Speckle-tracking echocardiography correctly identifies segmental left ventricular dysfunction induced by scarring in a rat model of myocardial infarction
    Zoran B Popovic
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am J Physiol Heart Circ Physiol 292:H2809-16. 2007
    Speckle-tracking echocardiography (STE) uses a two-dimensional echocardiographic image to estimate two orthogonal strain components...
  25. doi Update on myocarditis
    Ingrid Kindermann
    Universitatsklinikum des Saarlandes, Klinik fur Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Kirrberger Strasse 1, Homburg Saar, Germany
    J Am Coll Cardiol 59:779-92. 2012
    ..Further investigations by controlled, randomized studies are needed to definitively determine their role in the treatment of myocarditis...
  26. doi Echocardiography screening for rheumatic heart disease in Ugandan schoolchildren
    Andrea Beaton
    Children s National Medical Center, Department of Cardiology, 111 Michigan Ave, Washington, DC 20010, USA
    Circulation 125:3127-32. 2012
    ..b>Echocardiography-based screening improves detection of RHD in endemic regions...
  27. doi Transthoracic echocardiography to rule out paroxysmal atrial fibrillation as a cause of stroke or transient ischemic attack
    Raoul Stahrenberg
    Department of Cardiology and Pneumology, University of Gottingen, Gottingen, Germany
    Stroke 42:3643-5. 2011
    We assessed whether echocardiography can predict paroxysmal atrial fibrillation (PAF) in patients with cerebral ischemia presenting in sinus rhythm.
  28. pmc The conserved phosphoinositide 3-kinase pathway determines heart size in mice
    T Shioi
    Cardiovascular Division, Beth Israel Deaconess Medical Center and Departments of Medicine and Cell Biology, Harvard Medical School, Boston, MA 02215, USA
    EMBO J 19:2537-48. 2000
    ..Thus, the PI3K pathway is necessary and sufficient to promote organ growth in mammals...
  29. doi Epicardial fat: an additional measurement for subclinical atherosclerosis and cardiovascular risk stratification?
    Matthew R Nelson
    Mayo Clinic, Scottsdale, AZ, USA
    J Am Soc Echocardiogr 24:339-45. 2011
    The value of epicardial adipose tissue (EAT) thickness as determined by echocardiography in cardiovascular risk assessment is not well understood...
  30. ncbi Echocardiographic assessment of cardiac function in diabetic db/db and transgenic db/db-hGLUT4 mice
    Lisa M Semeniuk
    Department of Pharmacology and Therapeutics, University of Calgary, Calgary, Alberta, Canada T2N 4N1
    Am J Physiol Heart Circ Physiol 283:H976-82. 2002
    Control db/+ and diabetic db/db mice at 6 and 12 wk of age were subjected to echocardiography to determine whether contractile function was reduced in vivo and restored in transgenic db/db-human glucose transporter 4 (hGLUT4) mice (12 wk ..
  31. pmc The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse
    Eleonora Mezzaroma
    VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA 23298, USA
    Proc Natl Acad Sci U S A 108:19725-30. 2011
    ..Modulation of the inflammasome may therefore represent a unique therapeutic strategy to limit cell death and prevent heart failure after AMI...
  32. pmc Cardiac remodeling in a rat model of diet-induced obesity
    André Soares Leopoldo
    Department of Clinical and Cardiology, Universidade Estadual Paulista Julio de Mesquita Filho, Botucatu, Sao Paulo, Brazil
    Can J Cardiol 26:423-9. 2010
    ..Obesity also causes damage to myocardial ultrastructure, but its effect on myocardial function needs to be further clarified...
  33. doi Myocardial strain measurement with 2-dimensional speckle-tracking echocardiography: definition of normal range
    Thomas H Marwick
    University of Queensland, Department of Medicine, Princess Alexandra Hospital, Brisbane, Queensland, Australia
    JACC Cardiovasc Imaging 2:80-4. 2009
    The interpretation of wall motion is an important component of echocardiography but remains a source of variation between observers...
  34. ncbi Functional abnormalities in isolated left bundle branch block. The effect of interventricular asynchrony
    C L Grines
    Department of Internal Medicine, Ohio State University, Columbus
    Circulation 79:845-53. 1989
    ..This loss of septal contribution resulted in a reduction in global ejection fraction in LBBB compared to normals (54 +/- 7% compared with 62 +/- 5%, p less than 0.005).(ABSTRACT TRUNCATED AT 250 WORDS)..
  35. ncbi Diet-induced obesity causes metabolic, endocrine and cardiac alterations in spontaneously hypertensive rats
    Silvio A Oliveira Junior
    School of Physical Therapy, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil
    Med Sci Monit 16:BR367-73. 2010
    ..The current study analyzed the influence of dietary-induced obesity on metabolic, endocrine, and cardiac characteristics in SHR...
  36. ncbi Alterations of left ventricular hypertrophy in and survival of patients receiving hemodialysis: follow-up of an interventional study
    G M London
    Service d Hemodialyse, Hôpital F H Manhès, Fleury Merogis, France
    J Am Soc Nephrol 12:2759-67. 2001
    ..72 (95% confidence interval, 0.51 to 0.90) for mortality due to CV disease. These results show that a partial LVH regression in patients with ESRD had a favorable and independent effect on patients' all-cause and CV survival...
  37. ncbi Prevalence of left-ventricular systolic dysfunction and heart failure in the Echocardiographic Heart of England Screening study: a population based study
    M Davies
    Department of Cardiology, Selly Oak Hospital, Raddlebarn Road, Selly Oak, West Midlands, UK
    Lancet 358:439-44. 2001
    ..We assessed patients by history and examination, electrocardiography, and echocardiography. Prevalence of left-ventricular systolic dysfunction (defined as ejection fraction <40%) and heart failure ..
  38. ncbi Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction
    Matteo Vatta
    Department of Pediatrics Cardiology, Baylor College of Medicine, Houston, Texas, USA
    J Am Coll Cardiol 42:2014-27. 2003
    ..We evaluated the role of Cypher/ZASP in the pathogenesis of dilated cardiomyopathy (DCM) with or without isolated non-compaction of the left ventricular myocardium (INLVM)...
  39. ncbi Left ventricular mass index increase in early renal disease: impact of decline in hemoglobin
    A Levin
    Centre for Health Outcomes and Evaluation Sciences, St Paul s Hospital, Vancouver, Canada
    Am J Kidney Dis 34:125-34. 1999
    ..Canadian cohort study identifies factors associated with LVG, measured using two-dimensional-targeted M-mode echocardiography. Eight centers enrolled 446 patients, 318 of whom had protocol-mandated clinical, laboratory, and ..
  40. doi Early identification of mutation carriers in familial hypertrophic cardiomyopathy by combined echocardiography and tissue Doppler imaging
    Estelle Gandjbakhch
    AP HP, Hopital Pitie Salpetriere, Departement de Cardiologie, Paris F 75013, France
    Eur Heart J 31:1599-607. 2010
    ..However, data are limited. We performed a systematic analysis of echocardiography, TDI, and electrocardiogram (ECG) in familial HCM to identify parameters associated with genetic status.
  41. ncbi Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade
    Scott E Woodman
    Department of Molecular Pharmacology, Division of Hormone Dependent Tumor Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Biol Chem 277:38988-97. 2002
    ..hypertrophy, dilation, and reduced fractional shortening, as revealed by gated cardiac MRI and transthoracic echocardiography. Histological analysis reveals marked cardiac myocyte hypertrophy, with accompanying cellular infiltrates and ..
  42. doi Rheumatic heart disease screening by echocardiography: the inadequacy of World Health Organization criteria for optimizing the diagnosis of subclinical disease
    Eloi Marijon
    Universite Paris Descartes, AP HP, Hopital Europeen Georges Pompidou, France
    Circulation 120:663-8. 2009
    ..We hypothesized that adding morphological features to diagnostic criteria might have significant consequences in terms of case detection rates...
  43. doi Prognostic value of right ventricular dysfunction in patients with haemodynamically stable pulmonary embolism: a systematic review
    Olivier Sanchez
    Division of Respiratory and Intensive Care Medicine, Georges Pompidou European Hospital, 75015 Paris, France
    Eur Heart J 29:1569-77. 2008
    To determine the prognostic value of right ventricular (RV) dysfunction assessed by echocardiography or spiral computed tomography (CT), or by increased levels of cardiac biomarkers [troponin, brain natriuretic peptide (BNP) and pro-BNP] ..
  44. pmc Assessment of echocardiography and biomarkers for the extended prediction of cardiotoxicity in patients treated with anthracyclines, taxanes, and trastuzumab
    Heloisa Sawaya
    Cardiac Ultrasound Laboratory and Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Circ Cardiovasc Imaging 5:596-603. 2012
    ..The present study investigates whether early alterations of myocardial strain and blood biomarkers predict incident cardiotoxicity in patients with breast cancer during treatment with anthracyclines, taxanes, and trastuzumab...
  45. ncbi Two-dimensional strain-a novel software for real-time quantitative echocardiographic assessment of myocardial function
    Marina Leitman
    Cardiology Department, Assaf Harofeh Medical Center, Zerifin 70300, Israel
    J Am Soc Echocardiogr 17:1021-9. 2004
    ..We sought to assess the feasibility of 2-dimensional strain, a novel software for real-time quantitative echocardiographic assessment of myocardial function...
  46. doi Two- and three-dimensional speckle tracking echocardiography: clinical applications and future directions
    Monodeep Biswas
    Division of Cardiovascular Disease, University of Alabama at Birmingham, Alabama 35249, USA
    Echocardiography 30:88-105. 2013
    Two-dimensional speckle tracking echocardiography (2D STE) is a novel technique of cardiac imaging for quantifying complex cardiac motion based on frame-to-frame tracking of ultrasonic speckles in gray scale 2D images...
  47. ncbi Impact of arterial stiffening on left ventricular structure
    M J Roman
    Division of Cardiology and the Hypertension Center, Department of Medicine, Cornell University Medical College, New York, NY, USA
    Hypertension 36:489-94. 2000
    ..hundred seventy-six subjects (79 normotensive and 197 otherwise healthy hypertensive individuals) underwent echocardiography to assess left ventricular structure...
  48. doi American College of Chest Physicians/La Société de Réanimation de Langue Française statement on competence in critical care ultrasonography
    Paul H Mayo
    Department of Medicine, Long Island Jewish Medical Center, 410 Lakeville Road, New Hyde Park, NY 11140, USA
    Chest 135:1050-60. 2009
    ..To define competence in critical care ultrasonography (CCUS)...
  49. doi Left ventricular non-compaction revisited: a distinct phenotype with genetic heterogeneity?
    Erwin Oechslin
    Toronto Congenital Cardiac Centre for Adults, Peter Munk Cardiac Centre, University Health Network Toronto General Hospital, Toronto, Ontario, Canada
    Eur Heart J 32:1446-56. 2011
    ....
  50. doi Echocardiographic parameters are independently associated with increased cardiovascular events in patients with chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    Nephrol Dial Transplant 27:1064-70. 2012
    ..The aim of this study is to assess whether echocardiographic parameters are independently associated with increased CV events in patients with CKD Stages 3-5...
  51. ncbi The respiratory variation in inferior vena cava diameter as a guide to fluid therapy
    Marc Feissel
    Réanimation Médicale et Maladies Infectieuses, Centre Hospitalier de Belfort, Belfort, France
    Intensive Care Med 30:1834-7. 2004
    ..To investigate whether the respiratory variation in inferior vena cava diameter (DeltaD(IVC)) could be related to fluid responsiveness in mechanically ventilated patients...
  52. doi Echocardiographic evaluation of left atrial size and function: current understanding, pathophysiologic correlates, and prognostic implications
    Dominic Y Leung
    Liverpool Hospital, University of New South Wales, Sydney, New South Wales, Australia
    Am Heart J 156:1056-64. 2008
    ..In addition, an overview of the implications and clinical relevance of the findings of an enlarged left atrium, from currently available literature, is presented...
  53. ncbi Diabetes related cardiomyopathy time dependent echocardiographic evaluation in an experimental rat model
    M J Mihm
    Division of Pharmacology, College of Pharmacy, The Ohio State University, Columbus, USA
    Life Sci 69:527-42. 2001
    ..Furthermore, diastolic dysfunction precedes contractile abnormalities in the streptozotocin model, similar to events that occur in humans...
  54. ncbi Percutaneous implantation of the CoreValve self-expanding valve prosthesis in high-risk patients with aortic valve disease: the Siegburg first-in-man study
    Eberhard Grube
    Department of Cardiology Angiology, HELIOS Heart Center Siegburg, Ringstrasse 49, 53721 Siegburg, Germany
    Circulation 114:1616-24. 2006
    ....
  55. ncbi Closed-chest cell injections into mouse myocardium guided by high-resolution echocardiography
    Matthew L Springer
    Division of Cardiology, Department of Medicine, University of California, San Francisco, California 94143 0124, USA
    Am J Physiol Heart Circ Physiol 289:H1307-14. 2005
    ..We describe the use of high-resolution echocardiography to guide nonsurgical injections accurately into the mouse myocardial wall...
  56. ncbi Association of obesity with left ventricular remodeling and diastolic dysfunction in patients without coronary artery disease
    Brian D Powell
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
    Am J Cardiol 98:116-20. 2006
    ..No patients had coronary artery stenoses >50% of the luminal diameter, and all underwent echocardiography within the same 6-year period...
  57. pmc Echocardiographic parameters are independently associated with rate of renal function decline and progression to dialysis in patients with chronic kidney disease
    Szu Chia Chen
    Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 100 Tzyou First Road, Kaohsiung 807, Taiwan
    Clin J Am Soc Nephrol 6:2750-8. 2011
    ..This study is designed to assess whether echocardiographic parameters are associated with rate of renal function decline and progression to dialysis in CKD stage 3 to 5 patients...
  58. pmc The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice
    O F Bueno
    Department of Pediatrics, University of Cincinnati, Division of Molecular Cardiovascular Biology, Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    EMBO J 19:6341-50. 2000
    ..MEK1 transgenic mice showed a dramatic increase in cardiac function, as measured by echocardiography and isolated working heart preparation, without signs of decompensation over time...
  59. doi Epicardial adipose tissue thickness by echocardiography is a marker for the presence and severity of coronary artery disease
    S Eroglu
    Department of Cardiology, Baskent University Faculty of Medicine, 10 Sok No 45, 06490 Bahcelievler, Ankara, Turkey
    Nutr Metab Cardiovasc Dis 19:211-7. 2009
    ..We aimed to test the hypothesis that echocardiographic EAT thickness can be a marker for the presence and severity of coronary artery disease (CAD)...
  60. ncbi The left atrium: a biomarker of chronic diastolic dysfunction and cardiovascular disease risk
    Pamela S Douglas
    J Am Coll Cardiol 42:1206-7. 2003
  61. doi Left ventricular volume measurement with echocardiography: a comparison of left ventricular opacification, three-dimensional echocardiography, or both with magnetic resonance imaging
    Carly Jenkins
    Department of Medicine, University of Queensland, Princess Alexandra Hospital, Brisbane, Australia
    Eur Heart J 30:98-106. 2009
    Both contrast enhanced (CE) two-dimensional echocardiography (2DE) and three-dimensional echocardiography (3DE) have been proposed as techniques to improve the accuracy of left ventricular (LV) volume measurements...
  62. pmc Relation between aortic stiffness and left ventricular diastolic function in patients with hypertension, diabetes, or both
    M Eren
    Siyami Ersek Cardiothoracic Surgery Center, Cardiology Department, Istanbul, Turkey
    Heart 90:37-43. 2004
    ..To evaluate aortic function and its relation to left ventricular diastolic function in patients with hypertension, diabetes, or both, without coronary artery disease...
  63. doi Results of the Predictors of Response to CRT (PROSPECT) trial
    Eugene S Chung
    Lindner Clinical Trial Center, Cincinnati, OH 45219, USA
    Circulation 117:2608-16. 2008
    ..In a prospective, multicenter setting, the Predictors of Response to CRT (PROSPECT) study tested the performance of these parameters to predict CRT response...
  64. ncbi Recommendations for a standardized report for adult transthoracic echocardiography: a report from the American Society of Echocardiography's Nomenclature and Standards Committee and Task Force for a Standardized Echocardiography Report
    Julius M Gardin
    J Am Soc Echocardiogr 15:275-90. 2002
  65. pmc Effectiveness of late gadolinium enhancement to improve outcomes prediction in patients referred for cardiovascular magnetic resonance after echocardiography
    Timothy C Wong
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Cardiovasc Magn Reson 15:6. 2013
    b>Echocardiography (echo) is a first line test to assess cardiac structure and function...
  66. pmc Diastolic dysfunction and mortality in severe sepsis and septic shock
    Giora Landesberg
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem 91120, Israel
    Eur Heart J 33:895-903. 2012
    ..In contrast, diastolic dysfunction is often ignored and its role in determining early mortality from sepsis has not been adequately investigated...
  67. ncbi Abdominal aorta screening during transthoracic echocardiography
    Farideh Roshanali
    Day General Hospital, Tehran, Iran
    Echocardiography 24:685-8. 2007
    ..a modified abdominal ultrasound examination, performed as an extension of a routine diagnostic transthoracic echocardiography. This modified examination is arguably a simple, safe, quick, and accurate way to identify patients with ..
  68. doi Reference values for myocardial two-dimensional strain echocardiography in a healthy pediatric and young adult cohort
    Karen A Marcus
    Children s Heart Centre, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Am Soc Echocardiogr 24:625-36. 2011
    ..The aim of this study was to estimate left ventricular myocardial systolic function using 2DSTE imaging in a large cohort consisting of healthy children and young adults to establish reference strain values...
  69. pmc Right ventricular systolic pressure by echocardiography as a predictor of pulmonary hypertension in idiopathic pulmonary fibrosis
    Steven D Nathan
    Inova Fairfax Hospital, Falls Church, VA, USA
    Respir Med 102:1305-10. 2008
    ..Pulmonary hypertension (PH) commonly complicates the course of patients with idiopathic pulmonary fibrosis (IPF). It has a significant impact on outcomes and is, therefore, important to detect...
  70. doi Impact of systolic time intervals on the relationship between arterial stiffness and left ventricular hypertrophy
    Ho Ming Su
    Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Taiwan
    Atherosclerosis 223:171-6. 2012
    ....
  71. doi Clinical implication of mitral annular plane systolic excursion for patients with cardiovascular disease
    Kai Hu
    Department of Internal Medicine I, Comprehensive Heart Failure Center, University of Wurzburg, Oberdürrbacher Str 6, 97080 Wurzburg, Germany
    Eur Heart J Cardiovasc Imaging 14:205-12. 2013
    ..echocardiographic technologies nowadays, such as strain-rate imaging, speckle-tracking imaging, and 3D echocardiography, the use of MAPSE measurement is still especially helpful to evaluate LV systolic function in case of poor ..
  72. ncbi Cardiac lipid accumulation associated with diastolic dysfunction in obese mice
    Christina Christoffersen
    Departments of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark 2100
    Endocrinology 144:3483-90. 2003
    ..On echocardiography, the ratio of E to A transmitral flow velocities (an indicator of diastolic function) was 1.8 +/- 0...
  73. pmc Pulmonary hypertension: prevalence and mortality in the Armadale echocardiography cohort
    Geoff Strange
    Monash University, Victoria, Australia
    Heart 98:1805-11. 2012
    ..Pulmonary hypertension (PHT) lacks community prevalence and outcome data...
  74. doi Assessment of the aortic annulus by multislice computed tomography, contrast aortography, and trans-thoracic echocardiography in patients referred for transcatheter aortic valve implantation
    Apostolos Tzikas
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    Catheter Cardiovasc Interv 77:868-75. 2011
    We sought to determine the level of agreement and the reproducibility of trans-thoracic echocardiography (TTE), contrast aortography (CA) and multislice computed tomography (MSCT) for the assessment of the aortic annulus, in patients ..
  75. doi Circumferential and longitudinal strain in 3 myocardial layers in normal subjects and in patients with regional left ventricular dysfunction
    Marina Leitman
    Department of Cardiology, Assaf Harofeh Medical Center, Zerifin, Israel
    J Am Soc Echocardiogr 23:64-70. 2010
    ..The aim of this study was to analyze strain in 3 myocardial layers using speckle-tracking echocardiography.
  76. doi Early left ventricular mechanics abnormalities in prehypertension: a two-dimensional strain echocardiography study
    Vitantonio Di Bello
    Cardiac and Thoracic and Vascular Department, University of Pisa, Pisa, Italy
    Am J Hypertens 23:405-12. 2010
    ..in borderline prehypertensive (pre-HT) and hypertensive (HT) subjects through two-dimensional (2D)-strain echocardiography and then evaluate possible relations between cardiac parameters and insulin metabolism (homeostasis model ..
  77. ncbi Incidence of congenital heart disease in Beijing, China
    Xue yong Yang
    Department of Surgery, Pediatric Cardiac Center, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Chin Med J (Engl) 122:1128-32. 2009
    ..The current study was undertaken to determine the incidence of congenital heart disease in Beijing, China and to estimate the impact of fetal echocardiography on the incidence of liveborn congenital heart disease.
  78. doi The diagnostic value of physical examination and additional testing in primary care patients with suspected heart failure
    Johannes C Kelder
    Julius Center for Health Sciences and Primary Care, Room 6 101, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Circulation 124:2865-73. 2011
    ..Early diagnosis of nonacute heart failure is crucial because prompt initiation of evidence-based treatment can prevent or slow down further progression. To diagnose new-onset heart failure in primary care is challenging...
  79. doi Point-of-care echocardiography by pediatric emergency physicians
    Mindy Longjohn
    Division of Emergency Services, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA
    Pediatr Emerg Care 27:693-6. 2011
    Currently, pediatric emergency medicine (PEM) physicians have limited data on point-of-care echocardiography (POCE)...
  80. doi Diastolic dysfunction: improved understanding using emerging imaging techniques
    Daniel Daneshvar
    Cedars Sinai Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Am Heart J 160:394-404. 2010
    ..We review the role of contemporary techniques with echocardiography and cardiac magnetic resonance imaging (CMRI) in the assessment of diastolic dysfunction...
  81. pmc Feasibility and reliability of point-of-care pocket-sized echocardiography
    Garrett Newton Andersen
    Levanger Hospital, Nord Trøndelag Health Trust, Levanger, Norway
    Eur J Echocardiogr 12:665-70. 2011
    To study the reliability and feasibility of point-of-care pocket-sized echocardiography (POCKET) at the bedside in patients admitted to a medical department at a non-university hospital.
  82. ncbi Assessment of left ventricular rotation and torsion with two-dimensional speckle tracking echocardiography
    Hyung Kwan Kim
    Division of Cardiology, Department of Internal Medicine, Seoul National University College of Medicine, Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    J Am Soc Echocardiogr 20:45-53. 2007
    Speckle tracking echocardiography (STE) has a unique feature of angle independence and, thus, may provide a powerful means of assessing left ventricular (LV) torsion (LVtor)...
  83. pmc Novel echocardiographic techniques to assess left atrial size, anatomy and function
    Matteo Cameli
    Department of Cardiovascular Diseases, University of Siena, Italy
    Cardiovasc Ultrasound 10:4. 2012
    Three-dimensional echocardiography (3DE) and speckle tracking echocardiography (STE) have recently applied as imaging techniques to accurately evaluate left atrial (LA) size, anatomy and function...
  84. pmc Early detection and prediction of cardiotoxicity in chemotherapy-treated patients
    Heloisa Sawaya
    Cardiac Ultrasound Laboratory and Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 107:1375-80. 2011
    ..patients diagnosed with breast cancer who received anthracyclines and trastuzumab therapy underwent echocardiography and blood sampling at 3 time points (baseline and 3 and 6 months during the course of chemotherapy)...
  85. pmc Effects of selective heart rate reduction with ivabradine on left ventricular remodelling and function: results from the SHIFT echocardiography substudy
    Jean Claude Tardif
    Montreal Heart Institute, Universite de Montreal, 5000 Belanger Street, Montreal, Quebec, Canada H1T 1C8
    Eur Heart J 32:2507-15. 2011
    ..The SHIFT echocardiographic substudy evaluated the effects of ivabradine on left ventricular (LV) remodelling in heart failure (HF)...
  86. pmc Echocardiographic speckle-tracking based strain imaging for rapid cardiovascular phenotyping in mice
    Michael Bauer
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Circ Res 108:908-16. 2011
    ..Transthoracic echocardiography is the principal method currently used for assessing cardiac structure and function; however, standard ..
  87. ncbi Transthoracic echocardiography for cardiopulmonary monitoring in intensive care
    M B Jensen
    Aarhus University Hospital, Department of Anaesthesiology and Intensive Care, Skejby Sygehus, Denmark
    Eur J Anaesthesiol 21:700-7. 2004
    ..To evaluate the feasibility of an abbreviated focus assessed transthoracic echocardiographic protocol, consisting of four standardized acoustic views for cardiopulmonary screening and monitoring...
  88. ncbi Clinical, imaging, and pathological characteristics of left ventricular thrombus: a comparison of contrast-enhanced magnetic resonance imaging, transthoracic echocardiography, and transesophageal echocardiography with surgical or pathological validation
    Monvadi B Srichai
    Center for Integrated Non Invasive Cardiovascular Imaging of Department of Radiology Section of Cardiovascular Imaging, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am Heart J 152:75-84. 2006
    ..characteristics of confirmed LV thrombus and compared the diagnostic value of contrast-enhanced magnetic resonance imaging (MRI) with transthoracic (TTE) and transesophageal echocardiography (TEE) for the diagnosis of LV thrombi.
  89. ncbi Left ventricular remodeling after primary coronary angioplasty: patterns of left ventricular dilation and long-term prognostic implications
    Leonardo Bolognese
    Division of Cardiology, S Donato Hospital, Arezzo, Italy
    Circulation 106:2351-7. 2002
    ..The prevalence, course, and prognostic value of LV remodeling after primary PTCA are still to be clarified...
  90. pmc Usefulness of the high triglyceride-to-HDL cholesterol ratio to identify cardiometabolic risk factors and preclinical signs of organ damage in outpatient children
    Procolo Di Bonito
    Department of Internal Medicine, S Maria delle Grazie, Pozzuoli Hospital, Naples, Italy
    Diabetes Care 35:158-62. 2012
    ..To evaluate whether the high triglyceride-to-HDL cholesterol (TG-to-HDL-C) ratio is associated with cardiometabolic risk (CMR) factors and preclinical signs of organ damage in an outpatient population of white children and adolescents...
  91. ncbi Cardiac hypertrophy is not a required compensatory response to short-term pressure overload
    J A Hill
    Division of Cardiovascular Diseases, Department of Internal Medicine, Department of Veterans Affairs, University of Iowa College of Medicine, Iowa City 52242 1081, USA
    Circulation 101:2863-9. 2000
    ..Cardiac hypertrophy is considered a necessary compensatory response to sustained elevations of left ventricular (LV) wall stress...
  92. doi S100A8/A9 aggravates post-ischemic heart failure through activation of RAGE-dependent NF-κB signaling
    H Christian Volz
    Department of Medicine III, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
    Basic Res Cardiol 107:250. 2012
    ..Our study provides evidence that sustained activation of S100A8/A9 critically contributes to the development of post-ischemic HF driving the progressive course of HF through activation of RAGE...
  93. ncbi Effects of deflazacort on left ventricular function in patients with Duchenne muscular dystrophy
    Candice K Silversides
    Toronto Congenital Cardiac Centre for Adults, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada
    Am J Cardiol 91:769-72. 2003
  94. pmc Cardiac involvement in Wegener's granulomatosis resistant to induction therapy
    Tomasz Miszalski-Jamka
    Center for Diagnosis, Prevention and Telemedicine, John Paul II Hospital, ul Pradnicka 80, 31 202 Krakow, Poland
    Eur Radiol 21:2297-304. 2011
    ..The aim of the study was to assess cardiac involvement in patients with Wegener's granulomatosis (WG), who failed to achieve remission following >6 months induction therapy for life or organ threatening disease...
  95. ncbi Transposition of the great arteries
    Carole A Warnes
    Division of Cardiovascular Diseases and Department of Internal Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Circulation 114:2699-709. 2006
    ..All patients should be seen periodically in a center where expertise in the clinical evaluation, imaging, and hemodynamic assessment of adult congenital heart disease is available...
  96. pmc Dyssynchrony by speckle-tracking echocardiography and response to cardiac resynchronization therapy: results of the Speckle Tracking and Resynchronization (STAR) study
    Hidekazu Tanaka
    University of Pittsburgh, Scaife Hall 564, 200 Lothrop Street, Pittsburgh, PA 15213 2582, USA
    Eur Heart J 31:1690-700. 2010
    The Speckle Tracking and Resynchronization (STAR) study used a prospective multi-centre design to test the hypothesis that speckle-tracking echocardiography can predict response to cardiac resynchronization therapy (CRT).
  97. doi Cardiac magnetic resonance detection of myocardial scarring in hypertrophic cardiomyopathy: correlation with histopathology and prevalence of ventricular tachycardia
    Deborah H Kwon
    Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 54:242-9. 2009
    ....
  98. pmc Low diagnostic yield of elective coronary angiography
    Manesh R Patel
    Duke Clinical Research Institute, Duke University, Durham, NC 27715, USA
    N Engl J Med 362:886-95. 2010
    ..We determined patterns of noninvasive testing and the diagnostic yield of catheterization among patients with suspected coronary artery disease in a contemporary national sample...
  99. doi Combined risk stratification with computerized tomography /echocardiography and biomarkers in patients with normotensive pulmonary embolism
    Savas Ozsu
    Karadeniz Technical University, School of Medicine, Department of Chest, Trabzon, Turkey
    Thromb Res 126:486-92. 2010
    Right ventricular dysfunction (RVD) detected by computerized tomography (CT)/echocardiography or elevated biomarkers is associated with a poor prognosis for pulmonary embolism (PE)...
  100. ncbi Univentricular heart
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, 5000 Belanger St, Montreal, Quebec, H1T 1C8, Canada
    Circulation 115:800-12. 2007
    ..Although the present report touches on issues applicable to neonates and children with univentricular hearts, the focus is on information of interest and relevance to the adult cardiologist...
  101. pmc Prospective evaluation of right ventricular function and functional status 6 months after acute submassive pulmonary embolism: frequency of persistent or subsequent elevation in estimated pulmonary artery pressure
    Jeffrey A Kline
    Department of Emergency Medicine, Emergency Medicine Research, Carolinas Medical Center, Charlotte, NC 28323 2861, USA
    Chest 136:1202-10. 2009
    ..The aim of this work was to document the rate of pulmonary hypertension, as assessed noninvasively by estimated right ventricular systolic pressure (RVSP) of >or= 40 mm Hg 6 months after the diagnosis of submassive PE...

Research Grants74

  1. The role of IKK beta in cardiomyocytes at baseline and following stress
    MATTHEW PETER COGGINS; Fiscal Year: 2013
    ..The principal investigator has completed a clinical fellowship in cardiology and echocardiography at Massachusetts General Hospital and seeks to expand his scientific skills, and his interest in the ..
  2. JNK exacerbates ischemia/reperfusion injury in hyperglycemic subjects.
    Keith A Webster; Fiscal Year: 2010
    ..In Aim 1 we will determine infarction and remodeling over time by high-definition echocardiography and micro-MRI...
  3. Aldosterone Action In The Brain, Hypertension and Inflammation
    ELISE PEERY GOMEZ-SANCHEZ; Fiscal Year: 2012
    ..with spectral analysis of wave form to assess baroreceptor function and sympathetic drive, and doppler-echocardiography will be used to asses hemodynamic changes and cardiac dysfunction...
  4. Targeting Cell Death to Prevent Ventricular Remodeling and Heart Failure
    Abhinav Diwan; Fiscal Year: 2011
    ..of Nix and Bnip3 will be subjected to pressure overload modeling and serially evaluated by noninvasive echocardiography. These studies will identify potential therapeutic targets to improve outcomes in heart failure, stemming ..
  5. JACKSON HEART STUDY
    HERMAN ALFRED TAYLOR; Fiscal Year: 2009
    ..history, anthropometry, resting and ambulatory blood pressure, phlebotomy and 24-hour urine collection, ECG, echocardiography, and pulmonary function...
  6. JACKSON HEART STUDY
    Asoka Srinivasan; Fiscal Year: 2010
    ..history, anthropometry, resting and ambulatory blood pressure, phlebotomy and 24-hour urine collection, ECG, echocardiography, and pulmonary function...
  7. JACKSON HEART STUDY
    Herman Taylor; Fiscal Year: 2010
    ..history, anthropometry, resting and ambulatory blood pressure, phlebotomy and 24-hour urine collection, ECG, echocardiography, and pulmonary function...
  8. JACKSON HEART STUDY
    HERMAN ALFRED TAYLOR; Fiscal Year: 2009
    ..history, anthropometry, resting and ambulatory blood pressure, phlebotomy and 24-hour urine collection, ECG, echocardiography, and pulmonary function...
  9. JACKSON HEART STUDY
    ASOKA S SRINIVASAN; Fiscal Year: 2013
    ..history, anthropometry, resting and ambulatory blood pressure, phlebotomy and 24-hour urine collection, ECG, echocardiography, and pulmonary function...
  10. JACKSON HEART STUDY
    ASOKA S SRINIVASAN; Fiscal Year: 2011
    ..history, anthropometry, resting and ambulatory blood pressure, phlebotomy and 24-hour urine collection, ECG, echocardiography, and pulmonary function...
  11. A Rodent Model to Study Links Among Diet, Visceral Adipose and Cardiomyopathy
    MELINDA ANN FRYE; Fiscal Year: 2013
    ..tools for general laboratory techniques, including myocyte isolation, along with equipment for performing echocardiography. Additional resources will allow HPLC, mass spectrometry, electron microscopy, genomic analyses, advanced ..
  12. Role of murine induced pluripotent stem cells on the correction of cardiac and sk
    Diego Fraidenraich; Fiscal Year: 2010
    ..will be evaluated at the histological (immunohistochemistry, H&E, immunofluorescence) and functional (echocardiography, treadmill) level...
  13. Tadalafil for Pulmonary Hypertension Associated with Chronic Lung Disease
    SHARON IRENE SMITH ROUNDS; Fiscal Year: 2013
    ..Additional information that will be obtained includes non-invasive assessment by 2-dimensional echocardiography of pulmonary artery systolic pressure and right ventricular function, dyspnea severity, health related ..
  14. AKAP Regulation of PKA Targeting in the Heart
    Meredith Bond; Fiscal Year: 2009
    ..into normal and failing rat hearts in vivo;(iv) cardiac function assessment by transthoracic and M-mode echocardiography (echo) (v) immunofluorescence labeling and (vi) microscopy of cryostat sections of rat heart after adenoviral ..
  15. Endothelium-Myocardium Interaction in Netrin-1 Induced Cardioprotection
    HUA LINDA CAI; Fiscal Year: 2013
    ..Analyses of infarct size and cardiac Troponin I release, and echocardiography analysis of cardiac function, will be used to examine the cardioprotective effect of netrin-1 in vivo...
  16. Right Heart-Pulmonary Vascular Interactions in Bronchopulmonary Dysplasia
    Marlowe Eldridge; Fiscal Year: 2013
    ..questions, we propose to use a combination of state-of-the-art MR imaging, right heart catheterization, 3D echocardiography and exercise to reveal any abnormalities in the pulmonary vasculature, right heart, and their interactions in ..
  17. Monitoring of Cardiovascular Function in Infants By Transcutaneous Dye Dilution
    Istvan Seri; Fiscal Year: 2013
    ..Care Unit at Children's Hospital Los Angeles and compare CO values with those obtained by functional echocardiography. Currently, a strong clinical need exists for a minimally invasive technique, which can provide rapid, serial ..
  18. Mouse Models of Non-Syndromic Cardiac Progeria
    Ali J Marian; Fiscal Year: 2012
    ..We will assess survival by Kaplan-Meier survival analysis;cardiac structure and function by echocardiography;and conduction defects and arrhythmias by electrocardiography...
  19. Hypoplastic Left Heart Syndrome: Expression of RHD in the Fetus?
    Pirooz Eghtesady; Fiscal Year: 2013
    ..To extend these studies, we will compare groups of pregnant women referred for fetal echocardiography (echo) and found to have a pregnancy affected by (1) HLHS;(2) congenital heart disease other than HLHS;and (3)..
  20. Inflammation and Repair in Cardiac Ischemia-Reperfusion
    Lewis C Becker; Fiscal Year: 2011
    ..ischemia-reperfusion with measurement of infarct size and assessment of left ventricular function by echocardiography and pressure-volume loops and (2) post-ischemic inflammation of the cremaster muscle with assessment of ..
  21. ANGIOTENSINS, PROSTAGLANDINS-ADRENERGIC INTERACTIONS
    Kafait U Malik; Fiscal Year: 2013
    ..Adenovirus (Ad) cPLA2[unreadable] shRNA and Ad cPLA2[unreadable] DNA;3) telemetry for measuring BP and echocardiography for assessing cardiac function;4) histological, immunohistochemical, and fluorescence microscopy and ..
  22. Endogenous Cardiac Glycosides in AASK
    Brad C Astor; Fiscal Year: 2010
    ..Participants underwent numerous clinic visits, tissue Doppler echocardiography, and 240hour ambulatory blood pressure monitoring...
  23. Role of Microbial Translocation in Cardiopulmonary Disease in Children with HIV
    Alison Morris; Fiscal Year: 2013
    ..We find that MT is correlated with pulmonary hypertension on echocardiography, increased airway obstruction, impairment of diffusing capacity for carbon monoxide, and more rapid ..
  24. Statins for Pulmonary and Cardiac Complications of Chronic HIV (The SPARC Trial)
    Stephen R Wisniewski; Fiscal Year: 2013
    ..be randomized to treatment or placebo with 3 and 6 month measures of pulmonary function, computed tomography, echocardiography, carotid intima media thickness, flow-mediated dilation and inflammatory biomarkers...
  25. Phospholemman and Cardiac Contracility
    Joseph Y Cheung; Fiscal Year: 2013
    ..We will use a combination of in vivo (echocardiography, catheterization, transduction of exogenous genes by rAAV9 injection) and in vitro (patch-clamp, single ..
  26. CARDIA Echocardiography Reading Center
    Joao A C Lima; Fiscal Year: 2012
    Johns Hopkins University serves as the Echocardiography Reading Center for the Coronary Artery Risk Development in Young Adults (CARDIA) Study for the period 2009-13...
  27. Angiogenic tissue engineering to limit post-infarction ventricular remodeling
    Y Joseph Woo; Fiscal Year: 2012
    ..of microrevascularization on ischemic myocardial contractility will be determined with dobutamine stress echocardiography and myocardial tissue properties will be studied utilizing atomic force microscopy and tensile strength ..
  28. CARDIA ECHO RC CAN 9-8470189
    Joao Lima; Fiscal Year: 2009
    Johns Hopkins University serves as the Echocardiography Reading Center for the Coronary Artery Risk Development in Young Adults (CARDIA) Study for the period 2009-13...
  29. CARDIA ECHO RC
    Joao A C Lima; Fiscal Year: 2011
    Johns Hopkins University serves as the Echocardiography Reading Center for the Coronary Artery Risk Development in Young Adults (CARDIA) Study for the period 2009-13...
  30. CARDIA ECHO RC
    Joao Lima; Fiscal Year: 2010
    Johns Hopkins University serves as the Echocardiography Reading Center for the Coronary Artery Risk Development in Young Adults (CARDIA) Study for the period 2009-13...
  31. The Role of RAGE in Diabetes and Myocardial Infarction.
    KAREN O'SHEA; Fiscal Year: 2013
    ..We will assess differences in I/R-induced left ventricular dysfunction due to genetic strain by echocardiography. Additionally, we will perform more targeted studies of hypoxia/reoxygenation in cardiomyocytes isolated from ..
  32. EFFECT OF R1R2 OVER-EXPRESSION ON CARDIAC FUNCTION
    Michael Regnier; Fiscal Year: 2013
    ..that transgenic R1R2 over-expression mice (TG-R1R2) have elevated left ventricular (LV) function, measured by echocardiography and Langendorff perfusion. Here we propose a translational approach, i.e...
  33. Protein biomarkers of pulmonary hypertension in sickle cell disease
    Mark E McComb; Fiscal Year: 2013
    ..Current diagnosis is by right heart catheterization (RHC) as echocardiography is frequently inaccurate and may be falsely positive...
  34. The role of phosphorylation of Ulk1 by GSK-3b in myocardial autophagy and aging
    Peiyong Zhai; Fiscal Year: 2013
    ..Postmortem measurements of organ weight, left ventricular catheterization, pressure-volume loop analysis, echocardiography, measurements of cardiac fibrosis, cardiac myocyte size, apoptosis and necrosis will be applied to ..
  35. Randomized trial of inhaled nitric oxide to treat acute pulmonary embolism
    Jeffrey A Kline; Fiscal Year: 2013
    ..in arginase-1 and ADMA, but decreased L-arginine in the patients with submassive PE and RV dysfunction on echocardiography. In experimental PE, if guanylate cyclase is stimulated, the PVR can be normalized, and intracardiac ..
  36. The S1P1 receptor regulates sarcomere assembly and cardiac development
    Roland S Wu; Fiscal Year: 2013
    ..The effects of this disruption will then be assayed by echocardiography, immunohistochemistry, and electron microscopy.
  37. Role of CaMKII Phosphorylation of RyR in Pathological &Physiological Hypertrophy
    Jonathan L Respress; Fiscal Year: 2011
    ..Methods include echocardiography, transverse aortic constriction (TAC), intracardiac hemodynamic measurements, cell isolation and confocal ..
  38. Myosin ELC, a novel therapeutic target for FHC
    Danuta Szczesna-Cordary; Fiscal Year: 2013
    ..1C) The age-dependent morphology and function of mutated transgenic mouse hearts by histopathology, echocardiography, invasive hemodynamics and MRI...
  39. Acuson Sequoia C512 Echocardiography System
    Sandrine V Pierre; Fiscal Year: 2010
    ..b>Echocardiography is widely accepted as a valuable research tool for studying a broad range of cardiovascular disease processes ..
  40. Three-dimensional cardiac accelerometry for cardiac monitoring
    Michael J Russell; Fiscal Year: 2010
    ..is the standard screening tool for assessing cardiac function, and electrocardiography (ECG), ultrasound (echocardiography, ECHO) and nuclear myocardial perfusion imaging (MPI) are the modalities commonly used for detecting ischemia ..
  41. Infarct Repair with Mesenchymal Stem Cell Subpopulation
    Buddhadeb Dawn; Fiscal Year: 2013
    ..Serial echocardiography and a terminal hemodynamic study will be performed to assess left ventricular (LV) function and anatomy...
  42. Influence of the Enteric Microbiome on the Genesis of Bronchopulmonary Dysplasia
    Aaron Hamvas; Fiscal Year: 2013
    ..In this single center project, limited polysomnography and echocardiography will be used to non- invasively and longitudinally assess airspace and pulmonary vascular development in ..
  43. Cardiomyocyte Apoptosis and Cardioprotective Actions of Estrogen
    Jin Kyung Kim; Fiscal Year: 2013
    ..supplement and examine p38[unreadable], p38[unreadable], cardiac apoptosis in situ, and cardiac function by echocardiography. In Specific Aim 2, we will investigate how E2 mediates p38 MAPKs - p53 interaction...
  44. Modeling the genetic basis for human congenital heart disease in mice
    Cecilia W Lo; Fiscal Year: 2013
    ..We previously showed noninvasive mouse fetal echocardiography is highly effective for high throughput Cardiovascular phenotyping...
  45. Sorafenib for Hepatopulmonary Syndrome
    Steven M Kawut; Fiscal Year: 2013
    ..to an increased alveolar-arterial oxygen gradient (AaPO2) and intrapulmonary transit of bubbles visualized by echocardiography after injection of agitated saline...
  46. Regulation of sympathetic function by infarction
    Beth A Habecker; Fiscal Year: 2013
    ..to alter sympathetic regeneration and sympathetic neurochemical properties, and will combine that with echocardiography, ECG telemetry in conscious mice, and ex vivo optical mapping to determine how changes in sympathetic ..
  47. Pediatric Heart Network North Carolina Consortium
    Jennifer S Li; Fiscal Year: 2010
    ..quality of life, assessed by validated measures;2) ventricular filling parameters, assessed by tissue Doppler echocardiography;3) amount of myocardial scarring assessed by MRI;4) neurohormonal activation, BNP;biomarkers of collagen ..
  48. Pathophysiology of Heart Failure with a Normal Ejection Fraction in the Elderly
    Mathew S Maurer; Fiscal Year: 2010
    ..health status by standardized questionnaires, and LV volumes, mass and function by three dimensional echocardiography. This study will examine the role of anemia in the pathophysiology of elderly patients with HFNEF and ..
  49. Examining the Effects of High Protein Diet on Outcomes in Heart Failure Patients
    Lorraine S Evangelista; Fiscal Year: 2013
    ..Weight, BMI, waist circumference, dual-energy x-ray absorptiometry, 2D and Doppler echocardiography, cardiopulmonary exercise stress testing, six minute walk test, biochemical analyses (plasma lipid profiles, ..
  50. Longtitudinal Study of Dialysis
    Rulan S Parekh; Fiscal Year: 2012
    ..tomography (CT) for coronary and valvular calcium and CT angiography as well as validated outcomes from echocardiography, pulse wave velocity and ankle brachial index...
  51. Molecular Imaging of Ischemic Memory with Ultrasound - Transition to Humans
    Jonathan R Lindner; Fiscal Year: 2010
    ..in patients referred for non-invasive evaluation for coronary artery disease with stress or dobutamine echocardiography. PUBLIC HEALTH RELEVANCE: Current algorithms for the diagnosis of acute coronary syndromes (unstable angina ..
  52. Aldosterone, nitric oxide, myocardial fibrosis, and capillary loss in ESRD
    David M Charytan; Fiscal Year: 2013
    ..myocardial fibrosis and microvascular supply in individuals with ESRD as measured using tissue Doppler Echocardiography (TDI) and myocardial perfusion imaging (PET) scans, respectively;Aim 2) To test the hypothesis that L-..
  53. PROMISE Trial: SDCC
    Kerry L Lee; Fiscal Year: 2013
    ..care or an initial 'functional'stress testing strategy (using physician-selected stress imaging (echocardiography or nuclear) or exercise electrocardiography)) in low-intermediate coronary artery risk patients with chest ..
  54. PROMISE Trial: Clinical Coordinating Center
    Pamela Susan Douglas; Fiscal Year: 2013
    ..care or an initial 'functional'stress testing strategy (using physician-selected stress imaging (echocardiography or nuclear) or exercise electrocardiography)) in low-intermediate coronary artery risk patients with chest ..
  55. PROMISE Trial: EQOL Coordinating Center
    Daniel B Mark; Fiscal Year: 2013
    ..care or an initial 'functional'stress testing strategy (using physician-selected stress imaging (echocardiography or nuclear) or exercise electrocardiography)) in low-intermediate coronary artery risk patients with chest ..
  56. Novel function and mechanism of CFTR in heart failure
    DAYUE DARREL DUAN; Fiscal Year: 2012
    ..mouse, isolated working heart preparations, pressure-overload model of myocardial hypertrophy and HF, serial echocardiography, molecular biological and immunological techniques and mitochondrial GSH measurement and functional assays...
  57. Mechanisms of Reduced Fatty Acid Oxidation and Cardiac Dysfunction in Sepsis
    Konstantinos Drosatos; Fiscal Year: 2013
    ..his mentor and his advisors/collaborators that will provide him with technical knowledge on how to perform echocardiography, induction of heart failure in animal models, chromatin immunoprecipitation and high throughput analysis ..
  58. Libman-Sacks Endocarditis and NPSLE
    Carlos Roldan; Fiscal Year: 2009
    ..Our published data demonstrate that: 1) Libman-Sacks orthrombotic vegetations are detected by transesophageal echocardiography (TEE) in 35% of SLE patients;and 2) NPSLE affects 60% of patients...
  59. Surrogate markers for Severe Pulmonary Embolism
    JEFFREY KLINE; Fiscal Year: 2005
    b>Echocardiography can help risk-stratify the severity of pulmonary embolism (PE) diagnosed in normotensive patients. However, because echocardiography is not uniformly available in U.S...
  60. Mechanism of Vasopressin-Mediated Placental Vascular Resistance after Fetal Bypas
    Pirooz Eghtesady; Fiscal Year: 2010
    ..Increasingly, these defects can now be identified early in pregnancy (~20 weeks) by fetal echocardiography, allowing consideration of in utero therapy when postnatal outcomes are grim...
  61. DEVELOPING CELLULAR CARDIOMYOPLASTY FOR INJURED HEART
    DORIS TAYLOR; Fiscal Year: 2001
    ..temporal effects of myoblasts infused into the coronary circulation on global contractile function (by 2-d echocardiography) and ventricular morphology in control and infarcted hearts...
  62. QUANTITATIVE ULTRASONIC IMAGING FOR MYOCARDIAL VIABILITY
    Julio Perez; Fiscal Year: 1999
    ..of pressure-dimension indices of ventricular function, and refinement in quantitative myocardial contrast echocardiography. To accomplish these goals we propose to study patients with acute myocardial ischemia and chronic coronary ..
  63. IDIOPATHIC DILATED CARDIOMYOPATHY
    Virginia Michels; Fiscal Year: 1991
    ..The index cases of the study population will consist of 100 patients, in whom the diagnosis has been made by echocardiography or cardiac catheterization...
  64. COMPUTATIONAL METHODS IN CARDIAC FLUID DYNAMICS
    CHARLES PESKIN; Fiscal Year: 1990
    ..aspects of diagnostic cardiac imaging, the project includes plans to simulate color-Doppler flow imaging, echocardiography, contrast angiography, nuclear medicine (gated blood-pool) imaging, and possibly magnetic resonance imaging...
  65. ECHOCARDIOGRAPHIC ASSESSMENT OF MICROVASCULAR PERFUSION
    Kevin Wei; Fiscal Year: 2003
    ..has previously been productive in developing research and clinical applications for myocardial contrast echocardiography (MCE). This past research provided the P.I...
  66. 3D CORONARY RECONSTRUCTION AND MULTIMODALITY FUSION
    Shiuh Yung Chen; Fiscal Year: 2003
    ..from different modalities using the two-dimensional (2-D) display format such as coronary angiography, echocardiography, computed tomography (CT), magnetic resonance (MR) imaging, or radionuclide tomography...
  67. ECHOCARDIOGRAPHIC STROKE PREDICTORS IN A TRI-ETHNIC COMM
    Marco Di Tullio; Fiscal Year: 2003
    ..In recent years, he has focused on the use of echocardiography to identify new cardioembolic sources for ischemic stroke, especially patent foramen ovale and aortic arch ..
  68. PARADIGM SHIFTS IN CLINICAL ISCHEMIA DETECTION
    Philip Binkley; Fiscal Year: 2002
    ..This investigation tests the accuracy of two new methods of ischemia detection, contrast echocardiography and endocardial catheter mapping of electromechanical coupling, as compared to established nuclear perfusion ..
  69. PARADIGM SHIFTS IN CLINICAL ISCHEMIA DETECTION
    Philip Binkley; Fiscal Year: 2004
    ..This investigation tests the accuracy of two new methods of ischemia detection, contrast echocardiography and endocardial catheter mapping of electromechanical coupling, as compared to established nuclear perfusion ..