photon absorptiometry


Summary: A noninvasive method for quantitating bone mineral content. It is used especially in the diagnosis of osteoporosis and also in measuring bone mineralization in infants.

Top Publications

  1. ncbi Effect of weight loss on bone mineral content and bone mineral density in obese women
    M D Van Loan
    US Department of Agriculture, Western Human Nutrition Research Center, Presidio of San Francisco, CA 94129, USA
    Am J Clin Nutr 67:734-8. 1998
  2. ncbi Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial
    S R Cummings
    Department of Epidemiology and Biostatistics, University of California, San Francisco 94105, USA
    JAMA 280:2077-82. 1998
  3. ncbi A physical model for dual-energy X-ray absorptiometry--derived bone mineral density
    H Sievanen
    Bone Research Group, UKK Institute, Tampere, Finland
    Invest Radiol 35:325-30. 2000
  4. ncbi A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse
    A A Butler
    Vollum Institute, Oregon Health Sciences University, Portland 97201 3098, USA
    Endocrinology 141:3518-21. 2000
  5. ncbi A normative reference database study for Pronosco X-posure System
    D M Black
    University of California, San Francisco, CA 94106, USA
    J Clin Densitom 4:5-12. 2001
  6. ncbi Diagnosis of osteoporosis and assessment of fracture risk
    John A Kanis
    WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield S10 2RX, UK
    Lancet 359:1929-36. 2002
  7. ncbi Race and sex effects on the association between muscle strength, soft tissue, and bone mineral density in healthy elders: the Health, Aging, and Body Composition Study
    D R Taaffe
    Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland, USA
    J Bone Miner Res 16:1343-52. 2001
  8. ncbi Importance of precision in bone density measurements
    S L Bonnick
    Texas Woman s University, PO Box 425876, Denton, TX 76204, USA
    J Clin Densitom 4:105-10. 2001
  9. ncbi A meta-analysis of the effects of cigarette smoking on bone mineral density
    K D Ward
    The University of Memphis Center for Community Health, Tennessee, USA
    Calcif Tissue Int 68:259-70. 2001
  10. ncbi The fracture liaison service: success of a program for the evaluation and management of patients with osteoporotic fracture
    Alastair R McLellan
    Western Infirmary, Glasgow, UK
    Osteoporos Int 14:1028-34. 2003

Research Grants

Detail Information

Publications319 found, 100 shown here

  1. ncbi Effect of weight loss on bone mineral content and bone mineral density in obese women
    M D Van Loan
    US Department of Agriculture, Western Human Nutrition Research Center, Presidio of San Francisco, CA 94129, USA
    Am J Clin Nutr 67:734-8. 1998
    ..Further research is needed to determine the full effect of weight loss on BMC, bone area, and BMD...
  2. ncbi Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial
    S R Cummings
    Department of Epidemiology and Biostatistics, University of California, San Francisco 94105, USA
    JAMA 280:2077-82. 1998
    ..Alendronate sodium reduces fracture risk in postmenopausal women who have vertebral fractures, but its effects on fracture risk have not been studied for women without vertebral fractures...
  3. ncbi A physical model for dual-energy X-ray absorptiometry--derived bone mineral density
    H Sievanen
    Bone Research Group, UKK Institute, Tampere, Finland
    Invest Radiol 35:325-30. 2000
    ..The goal of this study was to develop and validate a physical model for appropriate interpretation of BMD...
  4. ncbi A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse
    A A Butler
    Vollum Institute, Oregon Health Sciences University, Portland 97201 3098, USA
    Endocrinology 141:3518-21. 2000
    ..Furthermore, male mc3r-/- mice also exhibit an approximately 50% reduction in locomotory behavior on the running wheel, suggesting reduced energy expenditure...
  5. ncbi A normative reference database study for Pronosco X-posure System
    D M Black
    University of California, San Francisco, CA 94106, USA
    J Clin Densitom 4:5-12. 2001
    ..The strong correlation of DXR-BMD from the X-posure System with DXA at the wrist from the Hologic machine suggests that the X-posure System may be an alternative to DXA at the wrist for the assessment of osteoporosis...
  6. ncbi Diagnosis of osteoporosis and assessment of fracture risk
    John A Kanis
    WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield S10 2RX, UK
    Lancet 359:1929-36. 2002
    ..Many treatments can be provided cost-effectively to men and women if hip fracture probability over 10 years ranges from 2% to 10% dependent on age...
  7. ncbi Race and sex effects on the association between muscle strength, soft tissue, and bone mineral density in healthy elders: the Health, Aging, and Body Composition Study
    D R Taaffe
    Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland, USA
    J Bone Miner Res 16:1343-52. 2001
    ..Where differences did occur, they were primarily by sex not race. To preserve BMD, maintaining or increasing LM in the elderly would appear to be an appropriate strategy, regardless of race or sex...
  8. ncbi Importance of precision in bone density measurements
    S L Bonnick
    Texas Woman s University, PO Box 425876, Denton, TX 76204, USA
    J Clin Densitom 4:105-10. 2001
    ..Until precision studies are performed, the least significant change cannot be determined for any level of statistical confidence, making the interpretation of serial studies impossible...
  9. ncbi A meta-analysis of the effects of cigarette smoking on bone mineral density
    K D Ward
    The University of Memphis Center for Community Health, Tennessee, USA
    Calcif Tissue Int 68:259-70. 2001
    ..Given the public health implications of smoking on bone health, it is important that this information be incorporated into smoking prevention and cessation efforts...
  10. ncbi The fracture liaison service: success of a program for the evaluation and management of patients with osteoporotic fracture
    Alastair R McLellan
    Western Infirmary, Glasgow, UK
    Osteoporos Int 14:1028-34. 2003
  11. ncbi Official Positions of the International Society for Clinical Densitometry and executive summary of the 2007 ISCD Pediatric Position Development Conference
    Sanford Baim
    Medical College of Wisconsin, Milwaukee, WI, USA
    J Clin Densitom 11:6-21. 2008
    ..This report describes the methodology and results of the 2007 Pediatric PDC, and a summary of all ISCD Official Positions, including the ones recently adopted by this 2007 Pediatric PDC and the 2007 Lansdowne, Virginia, USA Adult PDC...
  12. pmc Comparisons of percentage body fat, body mass index, waist circumference, and waist-stature ratio in adults
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    Am J Clin Nutr 89:500-8. 2009
    ..Body mass index (BMI), waist circumference (WC), and the waist-stature ratio (WSR) are considered to be possible proxies for adiposity...
  13. ncbi Relationship between body composition and bone mineral density in women with and without osteoporosis: relative contribution of lean and fat mass
    Saverio Gnudi
    Modulo Dipartimentale di Medicina Interna, Istituti Ortopedici Rizzoli, Via Pupilli 1, 40136 Bologna, Italy
    J Bone Miner Metab 25:326-32. 2007
    ..05), while TLM did not. In conclusion, our data indicate that both TFM and TLM affect bone density, with different physiological/pathological conditions modulating this relationship...
  14. ncbi Increased lipodystrophy is associated with increased exposure to highly active antiretroviral therapy in HIV-infected children
    Alessandra Vigano
    Department of Pediatrics, L Sacco Hospital, Via GB Grassi 74, 20157 Milan, Italy
    J Acquir Immune Defic Syndr 32:482-9. 2003
    ..To assess body composition changes in HIV-infected children receiving highly active antiretroviral therapy (HAART)...
  15. ncbi Evaluation of Lunar Prodigy dual-energy X-ray absorptiometry for assessing body composition in healthy persons and patients by comparison with the criterion 4-component model
    Jane E Williams
    MRC Childhood Nutrition Research Centre, Institute of Child Health, London, UK
    Am J Clin Nutr 83:1047-54. 2006
    ..Several studies have evaluated its accuracy in healthy persons; however, little attention has been directed to the same issue in patients...
  16. ncbi Waist circumference, dual-energy X-ray absortiometrically measured abdominal adiposity, and computed tomographically derived intra-abdominal fat area on detecting metabolic risk factors in obese women
    Kayoung Lee
    Department of Family Medicine, Inje University Busan Paik Hospital, Busan, Korea
    Nutrition 24:625-31. 2008
  17. pmc Body weight, body composition, and bone turnover changes in patients with spondyloarthropathy receiving anti-tumour necrosis factor {alpha} treatment
    K Briot
    Hopital Cochin, Departement de Rhumatologie, 27 rue du Faubourg St Jacques, 75014 Paris, France
    Ann Rheum Dis 64:1137-40. 2005
    ..To determine the changes in body weight, body composition, and bone turnover in patients with spondyloarthropathy (SpA) treated with anti-tumour necrosis factor alpha (TNFalpha)...
  18. pmc Female patients with low systemic BMD are prone to bone loss in Gruen zone 7 after cementless total hip arthroplasty
    Jessica J Alm
    Orthopaedic Research Unit, Department of Orthopaedic Surgery and Traumatology, Turku University Central Hospital and University of Turku, Finland
    Acta Orthop 80:531-7. 2009
    ..We investigated the association between early changes in periprosthetic bone mineral density (BMD) and patient-related factors...
  19. ncbi The bone mineral density in childhood study: bone mineral content and density according to age, sex, and race
    Heidi J Kalkwarf
    Division of General and Community Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    J Clin Endocrinol Metab 92:2087-99. 2007
    ..Low bone mass may increase risk of fracture. Several chronic medical conditions, medications, and lifestyle factors affect bone mineral accrual. Appropriate reference values are essential for identification of children with bone deficits...
  20. ncbi Periprosthetic bone loss after cemented total hip arthroplasty: a prospective 5-year dual energy radiographic absorptiometry study of 15 patients
    Petri K Venesmaa
    Department of Surgery, Kuopio University Hospital, Finland
    Acta Orthop Scand 74:31-6. 2003
    ..The lower the preoperative BMD, the higher was the postoperative bone loss. We found that after the phase of acute bone loss, further loss was minimal, reflecting merely the normal ageing of bone after uncomplicated THA...
  21. ncbi Effect of low-repetition jump training on bone mineral density in young women
    Takeru Kato
    Department of Clinical Nutrition, Faculty of Health Science, Suzuka Univ of Medical Science, Kishioka, 1001 1, Suzuka 510 0293, Japan
    J Appl Physiol (1985) 100:839-43. 2006
    ..From the results of the present study, low-repetition and high-impact jumps enhanced BMD at the specific bone sites in young women who had almost reached the age of peak bone mass...
  22. ncbi Contact quantitative ultrasound: an evaluation of precision, fracture discrimination, age-related bone loss and applicability of the WHO criteria
    M L Frost
    Osteoporosis Unit, Guy s Hospital, London, UK
    Osteoporos Int 10:441-9. 1999
    ..However, the widely accepted threshold of a T-score of less than -2.5 for the definition of osteoporosis may need modifying for the interpretation of QUS scans...
  23. ncbi Z score prediction model for assessment of bone mineral content in pediatric diseases
    K J Ellis
    US Department of Agriculture/Agricultural Research Service Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
    J Bone Miner Res 16:1658-64. 2001
    ..5. These preliminary findings indicate that the prediction model should prove useful in determining potential bone mineral deficits in individual pediatric patients...
  24. ncbi Effectiveness of instant vertebral assessment to detect prevalent vertebral fracture
    R D Chapurlat
    Department of Rheumatology and Bone Disease and INSERM Unit 403, Hopital E Herriot, 5 Place d Arsonval, 69437, Lyon, Cedex 03, France
    Osteoporos Int 17:1189-95. 2006
  25. ncbi Predictive equations for body fat and abdominal fat with DXA and MRI as reference in Asian Indians
    Kashish Goel
    Department of Medicine, Maulana Azad Medical College, New Delhi, India
    Obesity (Silver Spring) 16:451-6. 2008
  26. ncbi Prediction of fat and fat-free mass in male athletes using dual X-ray absorptiometry as the reference method
    A D Stewart
    Fitness Assessment and Sports Injury Centre, University of Edinburgh, UK
    J Sports Sci 18:263-74. 2000
    ..7 kg), although this explained a further 4% of the variation in DXA-derived fat. Fat-free mass was predicted best from four skinfolds, although the standard error of the estimate and coefficient of determination were unchanged...
  27. pmc Association between body composition and blood pressure in a contemporary cohort of 9-year-old children
    M A Brion
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Hum Hypertens 21:283-90. 2007
    ..In this analysis, because both fat and lean masses are associated with BP, BMI predicts BP at least as well as these components of body composition...
  28. ncbi Bone mineral density, body composition, and height in long-term survivors of acute lymphoblastic leukemia in childhood
    I M van der Sluis
    Division of Endocrinology, Department of Pediatrics, Sophia Children s Hospital, Rotterdam, The Netherlands
    Med Pediatr Oncol 35:415-20. 2000
    ..Therefore, we studied the long-term effects on bone mineral density (BMD), body composition, and growth in survivors of non-high-risk ALL treated with the ALL-6 protocol...
  29. ncbi Total body composition by DXA of 241 HIV-negative men and 162 HIV-infected men: proposal of reference values for defining lipodystrophy
    E Bonnet
    Unit of Infectious and Tropical Disease, INSERM U 563, Purpan Hospital, Toulouse, France
    J Clin Densitom 8:287-92. 2005
    ..We defined FMR standard values from the largest group of HIV-negative men to our knowledge. Applying FMR to HIV patients could help physicians to diagnose lipodystrophy earlier...
  30. pmc Detection of emphysema progression in alpha 1-antitrypsin deficiency using CT densitometry; methodological advances
    David G Parr
    Department of Respiratory Medicine, University Hospitals of Coventry and Warwickshire, Clifford Bridge Road, Coventry, CV2 2DX, UK
    Respir Res 9:21. 2008
    ..However, emphysema is frequently localised to sub-regions of the lung and targeted densitometric sampling may be more informative than whole lung assessment...
  31. ncbi Stress fracture in military recruits: gender differences in muscle and bone susceptibility factors
    T J Beck
    Department of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD 21287 0849, USA
    Bone 27:437-44. 2000
    ..07). Unlike the bone geometry differences, thigh muscle cross-sectional areas were virtually identical to those of the men, suggesting that the muscles of the women were not relatively weaker...
  32. ncbi Effects of calcium, dairy product, and vitamin D supplementation on bone mass accrual and body composition in 10-12-y-old girls: a 2-y randomized trial
    Sulin Cheng
    Department of Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland
    Am J Clin Nutr 82:1115-26; quiz 1147-8. 2005
    ..Little is known about the relative effectiveness of calcium supplementation from food or pills with or without vitamin D supplementation for bone mass accrual during the rapid growth period...
  33. ncbi Bone turnover and density in obese premenopausal women during moderate weight loss and calcium supplementation
    S A Shapses
    Department of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey 08901-8525, USA
    J Bone Miner Res 16:1329-36. 2001
    ..In contrast to our previous findings in postmenopausal women, premenopausal obese women who consume a low calcium diet do not lose bone over a 6-month period, whether their weight is stable or decreasing moderately...
  34. pmc Measuring body composition
    J C K Wells
    MRC Childhood Nutrition Centre, Institute of Child Health, London WC1, UK
    Arch Dis Child 91:612-7. 2006
    ..Simple techniques are adequate for many purposes, and simple regional data may often be of greater value than "whole body" values obtained by more sophisticated approaches...
  35. ncbi Osteoporosis in pediatric patients suffering from chronic inflammatory bowel disease with and without steroid treatment
    Frank Walther
    University Children s Hospital, Faculty of Medicine, University of Rostock, Rembrandtstrasse 16 17, D 18057 Rostock
    J Pediatr Gastroenterol Nutr 43:42-51. 2006
    ..To study the impact of these factors on development of osteopathy, we compared the rate of osteoporosis in steroid-naive and steroid-treated pediatric IBD patients...
  36. ncbi Validity of fan-beam dual-energy X-ray absorptiometry for measuring fat-free mass and leg muscle mass. Health, Aging, and Body Composition Study--Dual-Energy X-ray Absorptiometry and Body Composition Working Group
    M Visser
    Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland 20892, USA
    J Appl Physiol (1985) 87:1513-20. 1999
    ..86-0.96). MM by DEXA was higher than by CT in three regions. The results of this study suggest that fan-beam DEXA offers considerable promise for the measurement of total body FFM and leg MM in elderly persons...
  37. ncbi Estimation of bone mineral density by digital X-ray radiogrammetry: theoretical background and clinical testing
    A Rosholm
    Pronosco A S, Vedbaek, Hvidovre Hospital, University of Copenhagen, Denmark
    Osteoporos Int 12:961-9. 2001
    ..It is concluded that the DXR method offers a BMD estimate with a good correlation with distal forearm BMD, a low variation between geographical sites and a precision that potentially allows for relatively short observation intervals...
  38. ncbi Dual-energy X-ray absorptiometry and body composition: differences between devices and comparison with reference methods
    Laurence Genton
    Geneva University Hospital, Geneva, Switzerland
    Nutrition 18:66-70. 2002
  39. ncbi Body composition in normal weight, overweight and obese children: matched case-control analyses of total and regional tissue masses, and body composition trends in relation to relative weight
    J C K Wells
    MRC Childhood Nutrition Research Centre, Institute of Child Health, London, UK
    Int J Obes (Lond) 30:1506-13. 2006
    ..Childhood obesity is defined on the basis of weight and height, using body mass index (BMI). There is little detailed information on the body composition characteristic of overweight and obesity...
  40. ncbi Pubertal timing is an independent predictor of central adiposity in young adult males: the Gothenburg osteoporosis and obesity determinants study
    Jenny M Kindblom
    Bone Research Center at the Institute of Medicine, Sahlgrenska Universitetssjukhuset Sahlgrenska, Grona Straket 8, 413 45 Gothenburg, Sweden
    Diabetes 55:3047-52. 2006
    ..In conclusion, we demonstrate that early pubertal onset specifically predicts a central fat mass distribution, while a predominantly subcutaneous obese phenotype is strongly predicted by a high prepubertal BMI...
  41. ncbi Relation between hormones and body composition, including bone, in prepubertal children
    Sarah P Garnett
    Institute of Endocrinology and Diabetes and the Research and Development Office, The Children s Hospital at Westmead, Westmead, Australia
    Am J Clin Nutr 80:966-72. 2004
    ..However, data are lacking that address the extent to which concentrations of these hormones influence body composition, bone mass, and density in prepubertal children...
  42. ncbi Periprosthetic femoral bone loss after total knee arthroplasty: 1-year follow-up study of 69 patients
    Tarja A Soininvaara
    Department of Surgery, Savonlinna Central Hospital, Finland
    Knee 11:297-302. 2004
    ..019) correlated with BMD loss for the total metaphyseal region of interest (ROI), by repeated measures ANOVA. We suggest that the observed periprosthetic bone loss was mainly the result of prosthesis-related stress-shielding...
  43. ncbi Trunk fat and leg fat have independent and opposite associations with fasting and postload glucose levels: the Hoorn study
    Marieke B Snijder
    Institute for Research in Extramural Medicine, VU University Medical Center, Amsterdam, The Netherlands
    Diabetes Care 27:372-7. 2004
    ..The main goal was to determine which tissue in the trunk and legs, fat or lean tissue, is associated with measures of glucose metabolism...
  44. ncbi Bone mineral density and bone turnover in young adult survivors of childhood acute lymphoblastic leukaemia
    M Jarfelt
    Department of Paediatrics, Division of Haematology and Oncology, Sahlgrenska Academy of Göteborg University, Goteborg, Sweden
    Eur J Endocrinol 154:303-9. 2006
  45. ncbi High prevalence and correlates of low bone mineral density in young adults with sickle cell disease
    Redonda G Miller
    Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, MD 21287, USA
    Am J Hematol 81:236-41. 2006
    ..02), and low serum zinc concentrations (P < 0.01). The prevalence of osteopenia and osteoporosis in young adults with SCD is extremely high. Further research is needed to address fracture risk and therapeutic interventions...
  46. ncbi Vertebral fractures in osteoporosis: a new method for clinical assessment
    H K Genant
    Osteoporosis and Arthritis Research Group, Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
    J Clin Densitom 3:281-90. 2000
    ..We also review clinical data supporting the feasibility of visual evaluation of lateral spine images obtained using a fan-beam DXA system, and discuss the potential positive impact of this new methodology on clinical patient evaluation...
  47. ncbi Novel use of single X-ray absorptiometry for measuring breast density
    John A Shepherd
    Musuloskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, CA 94143, USA
    Technol Cancer Res Treat 4:173-82. 2005
    ..Using phantoms, BD(SXA) has been shown to have a long-term repeatability of better than 2% for a breast composition range of 0 to 100% fibroglandular density...
  48. ncbi Visual assessment of vertebral deformity by X-ray absorptiometry: a highly predictive method to exclude vertebral deformity
    J A Rea
    Osteoporosis Screening and Research Unit, Guy s Hospital, London, UK
    Osteoporos Int 11:660-8. 2000
    ..VXA may prove useful in the clinical evaluation of patients at risk of osteoporosis as an adjunct to BMD scans or in the selection of subjects for osteoporosis-related clinical trials...
  49. ncbi Skeletal status in adolescents with end-stage renal failure: a longitudinal study
    Wojciech Pluskiewicz
    Department and Clinic of Internal Diseases, Diabetology and Nephrology, Metabolic Bone Diseases Unit Zabrze, Silesian School of Medicine in Katowice, 3 Maja 13 15 Street, 41 807 Zabrze, Poland
    Osteoporos Int 16:289-95. 2005
    ..The lack of an increase observed in normal healthy subjects of the same age, and low values in Z-scores, indicates that skeletal status is seriously affected in subjects with ESRF...
  50. ncbi Evidence-based recommendations for monitoring bone disease and the response to enzyme replacement therapy in Gaucher patients
    Stephan vom Dahl
    Department of Internal Medicine, St Franziskus Hospital, Cologne, Germany
    Curr Med Res Opin 22:1045-64. 2006
    ..Enzyme replacement therapy reverses many of the clinical signs of Gaucher bone disease but early assessment and treatment, and regular monitoring, are essential in optimising outcomes...
  51. ncbi Pamidronate treatment of less severe forms of osteogenesis imperfecta in children
    Margaret Zacharin
    Department of Endocrinology and Diabetes, Royal Children s Hospital, Melbourne, Australia
    J Pediatr Endocrinol Metab 17:1511-7. 2004
    ..Bisphosphonate therapy improves bone quality in children with severe osteogenesis imperfecta (OI). Children with milder phenotypes also have prepubertal fractures, bone pain and reduced bone mass, predisposing them to adult osteoporosis...
  52. ncbi Bone geometry in response to long-term tennis playing and its relationship with muscle volume: a quantitative magnetic resonance imaging study in tennis players
    G Ducher
    EA 3895 Architecture du Tissu Osseux et Exercice Physique, Faculty of Sport Sciences, University of Orléans and U658 Caractérisation du Tissu Osseux par Imagerie, INSERM, Orleans, France
    Bone 37:457-66. 2005
    ..In addition to the muscle contractions, other mechanical stimuli seemed to exert a direct effect on bone tissue, contributing to the specific bone response to tennis playing...
  53. ncbi Bone mass in childhood is related to maternal diet in pregnancy
    J H Tobias
    Clinical Science at South Bristol, Bristol, UK
    Osteoporos Int 16:1731-41. 2005
    ..Our observation that constituents of maternal diet are related to DXA measures at age 9 is consistent with the hypothesis that the trajectory of bone development in childhood is programmed by early life factors...
  54. ncbi Aromatase inhibitors and bone health in women with breast cancer
    Amy Jo Chien
    Department of Internal Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    J Clin Oncol 24:5305-12. 2006
  55. pmc Pediatric DXA: technique and interpretation
    Larry A Binkovitz
    Department of Radiology, Columbus Children s Hospital, 700 Children s Way, Columbus, OH 43205, USA
    Pediatr Radiol 37:21-31. 2007
    ..Finally, the diagnosis of osteoporosis should not be made on DXA results alone but should take into account other patient factors...
  56. ncbi Comparison of body composition methods in overweight and obese children
    P J Gately
    School of Leisure and Sport, Leeds Metropolitan University, Leeds LS6 3QS, United Kingdom
    J Appl Physiol (1985) 95:2039-46. 2003
    ..In conclusion, in overweight and obese children, ADPLoh and TBWLoh were the most accurate methods of measuring %fat compared with a 4C model. However, all methods under consideration produced similar limits of agreement...
  57. ncbi Validation of DXA body composition estimates in obese men and women
    Joseph LaForgia
    School of Pharmacy and Medical Sciences, University of South Australia, South Australia, Australia
    Obesity (Silver Spring) 17:821-6. 2009
    ..2%BF). This error appears to be associated with tissue thickness indicating that the DXA device used may not be able to accurately account for beam hardening in obese cohorts...
  58. ncbi Changes in hand and generalised bone mineral density in patients with recent-onset rheumatoid arthritis
    M Güler-Yüksel
    Department of Rheumatology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands
    Ann Rheum Dis 68:330-6. 2009
  59. ncbi Bone mineral assessment by dual energy X-ray absorptiometry in children with inflammatory bowel disease: evaluation by age or bone area
    S F Ahmed
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Yorkhill, Glasgow, United Kingdom
    J Pediatr Gastroenterol Nutr 38:276-80. 2004
    ..Traditionally, bone mineral assessment by dual energy x-ray absorptiometry (DXA) involves comparison to age- and gender-matched reference ranges, and these studies in children with IBD show a high prevalence of osteopenia...
  60. ncbi Dual energy X-ray absorptiometry interpretation and reporting in children and adolescents: the 2007 ISCD Pediatric Official Positions
    Catherine M Gordon
    Division of Endocrinology, Children s Hospital Boston, Boston, MA 02115, USA
    J Clin Densitom 11:43-58. 2008
    ..The rationale and evidence for development of the Official Positions are provided. Given the sparse data currently available in many of these areas, it is likely that these positions will change over time as new data become available...
  61. ncbi Longitudinal changes of lumbar bone mineral density (BMD) in patients with GH deficiency after discontinuation of treatment at final height; timing and peak values for lumbar BMD
    Giampiero Igli Baroncelli
    Endocrine Unit, Division of Pediatrics, Department of Reproductive Medicine and Pediatrics, University of Pisa, Pisa, Italy
    Clin Endocrinol (Oxf) 60:175-84. 2004
    ..Moreover, the changes of lumbar BMD after the attainment of the peak were assessed for a period of 2 years. The results of patients were compared with those obtained in age- and sex-matched healthy controls...
  62. ncbi Dual energy X-ray absorptiometry (DEXA) measurements of bone density and body composition: promise and pitfalls
    L K Bachrach
    Department of Pediatrics, Pediatric Endocrinology, Stanford University School of Medicine, CA 94305 5208, USA
    J Pediatr Endocrinol Metab 13:983-8. 2000
    ..In conclusion, DEXA is a valuable tool for assessing pediatric bone health, but accurate interpretation of densitometry results requires recognition of a myriad of pitfalls...
  63. ncbi Usefulness of anthropometry and DXA in predicting intra-abdominal fat in obese men and women
    E G Kamel
    Department of Medicine and Therapeutics, University of Aberdeen, Scotland, UK
    Obes Res 8:36-42. 2000
    ..To investigate the usefulness of anthropometry and DXA in predicting intra-abdominal fat (IAF) in obese men and women...
  64. ncbi Bone mineral density in acute stroke patients: low bone mineral density may predict first stroke in women
    L Jørgensen
    Institute of Community Medicine, University of Tromsø, Norway
    Stroke 32:47-51. 2001
    ..Thus, low bone mineral density (BMD) and high stroke risk may be related. We examined the relationship between BMD and acute stroke in noninstitutionalized men and women aged >/=60 years...
  65. ncbi Cortical hand bone loss after 1 year in early rheumatoid arthritis predicts radiographic hand joint damage at 5-year and 10-year follow-up
    M Hoff
    Department of Rheumatology, St Olav s Hospital, University Hospital in Trondheim, Trondheim, Norway
    Ann Rheum Dis 68:324-9. 2009
    ..To examine 1-year hand bone loss in early rheumatoid arthritis (RA) as a predictor of radiographic damage at 5-year and 10-year follow-up..
  66. ncbi The prediction of visceral fat by dual-energy X-ray absorptiometry in the elderly: a comparison with computed tomography and anthropometry
    M B Snijder
    Institute for Research in Extramural Medicine, Vrije Universiteit, Amsterdam, The Netherlands
    Int J Obes Relat Metab Disord 26:984-93. 2002
    ..The aim of the present study is to investigate whether the dual-energy X-ray absorptiometry (DXA) method, possibly combined with anthropometry, offers a good alternative to CT for the prediction of visceral fat in the elderly...
  67. ncbi Bone mineral density and osteoporosis in rural and urban women. Epidemiological study of the Lublin region (Eastern Poland)
    R S Filip
    Department of Public Health, Institute of Agricultural Medicine, Jaczewskiego 2, 20 950 Lublin, Poland
    Ann Agric Environ Med 8:221-6. 2001
    ..6%. In women between 45-55 years the prevalence of osteoporosis was 5.7 % and of osteopenia 25.6%. In women older than 55 years of age osteoporosis was observed in 18.5% and osteopenia in 40.7%...
  68. ncbi Environmental exposure to cadmium, forearm bone density, and risk of fractures: prospective population study. Public Health and Environmental Exposure to Cadmium (PheeCad) Study Group
    J A Staessen
    The Hypertensie en Cardiovasculaire Revalidatie Eenheid, Departement Moleculair en Cardiovasculair Onderzoek, Katholieke Universiteit Leuven, Belgium
    Lancet 353:1140-4. 1999
    ..Chronic low-level exposure to cadmium may promote calcium loss via urinary excretion. We undertook a prospective population study to investigate whether environmental exposure to cadmium lowers bone density and increases risk of fractures...
  69. ncbi Bone mineral density and body composition and influencing factors in children with rheumatic diseases treated with corticosteroids
    D Mul
    Department of Paediatrics, University Hospital Rotterdam and Sophia Children s Hospital, The Netherlands
    J Pediatr Endocrinol Metab 15:187-92. 2002
    ..57 (p <0.001 compared to 0). In conclusion, BMD and body composition in children with rheumatic disease treated with CS are influenced by physical activity, as well as corticosteroid treatment and type of rheumatic disease...
  70. ncbi Bone mineral content and collagen defects in osteogenesis imperfecta
    A M Lund
    Department of Clinical Genetics, Rigshospitalet, Copenhagen, Denmark
    Acta Paediatr 88:1083-8. 1999
  71. ncbi Effect of menatetrenone on bone mineral density and incidence of vertebral fractures in postmenopausal women with osteoporosis: a comparison with the effect of etidronate
    J Iwamoto
    Department of Sports Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan
    J Orthop Sci 6:487-92. 2001
  72. pmc Lower extremity muscle mass predicts functional performance in mobility-limited elders
    K F Reid
    Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr Health Aging 12:493-8. 2008
    ..This study examined the influence of lower extremity body composition and muscle strength on the severity of mobility-disability in community-dwelling older adults...
  73. ncbi A new approach to the development of assessment guidelines for osteoporosis
    J A Kanis
    WHO Centre for Metabolic Bone Diseases, University of Sheffield, UK
    Osteoporos Int 13:527-36. 2002
  74. ncbi Multisite quantitative ultrasound: precision, age- and menopause-related changes, fracture discrimination, and T-score equivalence with dual-energy X-ray absorptiometry
    K M Knapp
    Radiological Sciences, Guy s, Kings and St Thomas Medical School, Guy s Hospital, London, UK
    Osteoporos Int 12:456-64. 2001
  75. ncbi Bone mass and soft tissue composition in adolescents with anorexia nervosa
    S W Kooh
    Division of Endocrinology, University of Toronto, Ontario, Canada
    Bone 19:181-8. 1996
    ..These results were independent of methods used for the measurements...
  76. pmc Hand cortical bone mass and its associations with radiographic joint damage and fractures in 50-70 year old female patients with rheumatoid arthritis: cross sectional Oslo-Truro-Amsterdam (OSTRA) collaborative study
    G Haugeberg
    Department of Rheumatology, Sørlandet Hospital, N 4604 Kristiansand S, Norway
    Ann Rheum Dis 63:1331-4. 2004
    ..To investigate the relationship between hand bone mineral density (BMD) and radiographic joint damage, and between hand BMD and fractures in 50-70 year old women with longstanding RA...
  77. ncbi Bone mass after treatment of malignant lymphoma in childhood
    K Nysom
    Section of Paediatric Haematology and Oncology, The Juliane Marie Centre, Rigshospitalet, Copenhagen, Denmark
    Med Pediatr Oncol 37:518-24. 2001
    ..Previous studies of the bone mass of childhood cancer survivors often lacked adequate local reference data, and survivors of malignant lymphoma were never analyzed separately...
  78. ncbi Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70 to 79: the health, aging and body composition study
    Marjolein Visser
    Institute for Research in Extramural Medicine, Faculty of Medicine, Vrije Universiteit, Amsterdam, The Netherlands
    J Am Geriatr Soc 50:897-904. 2002
    ..Our aim was to determine whether low leg muscle mass and greater fat infiltration in the muscle were associated with poor lower extremity performance (LEP)...
  79. ncbi Variability in densitometric assessment of pulmonary emphysema with computed tomography
    M Els Bakker
    Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands, and the Department of Respiratory Medicine, Gentofte Hospital, Hellerup, Denmark
    Invest Radiol 40:777-83. 2005
  80. ncbi Instant vertebral assessment: a noninvasive dual X-ray absorptiometry technique to avoid misclassification and clinical mismanagement of osteoporosis
    S L Greenspan
    University of Pittsburgh Medical Center, Osteoporosis Prevention and Treatment Center, Lilliane S Kaufmann Medical Building, Suite 1110, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
    J Clin Densitom 4:373-80. 2001
    ..We conclude that IVA is a useful adjunct in the clinical identification of osteoporosis and may prevent mismanagement of osteoporotic patients...
  81. ncbi Bone mineral density in children with celiac disease. Effect of a Gluten-free diet
    C Tau
    Metabolismo Cálcico y Oseo, Endocrinologia, Hospital de Pediatria J P Garrahan, Buenos Aires, Argentina
    Eur J Clin Nutr 60:358-63. 2006
    ..To assess the degree of osteopenia in children with celiac disease (CD) at the time of diagnosis and the effect of a gluten-free diet (GFD)...
  82. ncbi Comparisons between Hologic QDR 1000W, QDR 4500A, and Lunar Expert dual-energy X-ray absorptiometry scanners used for measuring total body bone and soft tissue
    P Tothill
    Department of Medical Physics, Western General Hospital, Edinburgh, United Kingdom
    Ann N Y Acad Sci 904:63-71. 2000
    ..With all three scanners, wrapping lard around the limbs of a volunteer, to simulate weight change, changed the apparent BMC and BMD...
  83. ncbi Screening for osteoporosis using easily obtainable biometrical data: diagnostic accuracy of measured, self-reported and recalled BMI, and related costs of bone mineral density measurements
    D J van der Voort
    University of Maastricht, Department of General Practice, The Netherlands
    Osteoporos Int 11:233-9. 2000
    ..More research is needed before age and BMI can be included in any screening program. As regards practical considerations alone, measurements of BMD could be implemented within the screening program for breast cancer...
  84. ncbi A prospective evaluation of the awareness, knowledge, risk factors and current treatment of osteoporosis in a cohort of elderly subjects
    A G Juby
    Department of Medicine, University of Alberta Hospital, Edmonton, Canada
    Osteoporos Int 12:617-22. 2001
    ..Proactive treatment requests from patients need to be encouraged, especially with the future demographic shift...
  85. ncbi Skeletal muscle mass and muscle strength in relation to lower-extremity performance in older men and women
    M Visser
    Institute for Research in Extramural Medicine, Faculty of Medicine, Vrije Universiteit, Amsterdam, The Netherlands
    J Am Geriatr Soc 48:381-6. 2000
    ..We tested the hypothesis that persons with lower muscle mass or muscle strength have poorer lower-extremity performance (LEP)...
  86. ncbi Digital X-ray radiogrammetry combined with semiautomated analysis of joint space widths as a new diagnostic approach in rheumatoid arthritis: a cross-sectional and longitudinal study
    J Bottcher
    Friedrich Schiller University Jena, Jena, Germany
    Arthritis Rheum 52:3850-9. 2005
  87. pmc Bone loss in unclassified polyarthritis and early rheumatoid arthritis is better detected by digital x ray radiogrammetry than dual x ray absorptiometry: relationship with disease activity and radiographic outcome
    T Jensen
    Department of Rheumatology, H S Hvidovre Hospital, University of Copenhagen, DK 2650 Hvidovre, Denmark
    Ann Rheum Dis 63:15-22. 2004
  88. ncbi Bone mineral density and alterations of bone metabolism in children and adolescents with type 1 diabetes mellitus
    Gulay Karaguzel
    Division of Pediatric Endocrinology, Department of Pediatrics, School of Medicine, Akdeniz University, Antalya, Turkey
    J Pediatr Endocrinol Metab 19:805-14. 2006
    ..To analysis bone mineral density (BMD) and bone turnover markers in children and adolescents with type 1 diabetes mellitus (DM1) and to establish possible correlations with duration of the disease and degree of metabolic control...
  89. ncbi Long-term corticosteroid replacement and bone mineral density in adult women with classical congenital adrenal hyperplasia
    Jeremy A King
    Division of Reproductive Endocrinology, Department of Gynecology and Obstetrics, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
    J Clin Endocrinol Metab 91:865-9. 2006
    ..Concern has been raised regarding the potential impact of chronic glucocorticoid therapy on the bone mineral density (BMD) of patients with congenital adrenal hyperplasia (CAH)...
  90. pmc Hand bone densitometry: a more sensitive standard for the assessment of early bone damage in rheumatoid arthritis
    Glenn Haugeberg
    Department of Rheumatology Sørlandet Hospital, Kristiansand, Norway
    Ann Rheum Dis 66:1513-7. 2007
    ..To examine the role of hand dual-energy x ray absorptiometry (DEXA) compared with radiography in the assessment of bone involvement in patients with early rheumatoid arthritis (RA) who have active disease...
  91. ncbi Changes in the bone mineral density in the acetabulum and proximal femur after cementless total hip replacement: alumina-on-alumina versus alumina-on-polyethylene articulation
    Y H Kim
    Ewha Womans University College of Medicine, Dongdaemun Hospital, 70, ChongRo 6 Ga, Chongro Gu, Seoul 110 783, Korea
    J Bone Joint Surg Br 89:174-9. 2007
    ..049) in both groups. There was thus no significant difference in the bone remodelling of the acetabulum and femur five years after total hip replacement in those two groups where the only difference was in the acetabular liner...
  92. ncbi MTHFR c.677C>T polymorphism as an independent predictor of peak bone mass in Danish men--results from the Odense Androgen Study
    Bo Abrahamsen
    Department of Endocrinology, Odense University Hospital, Odense, Denmark
    Bone 38:215-9. 2006
    ..In conclusion, significant skeletal effects of this common polymorphism were present at the lumbar spine in men at the age of 25 years...
  93. ncbi Lactation among adolescent mothers and subsequent bone mineral density
    Caroline J Chantry
    Department of Pediatrics at the University of California Davis Medical Center, Sacramento, CA 95817, USA
    Arch Pediatr Adolesc Med 158:650-6. 2004
    ..To investigate the association of breastfeeding during adolescence with bone mineral density (BMD) during young adulthood...
  94. ncbi Predictive value of a preoperative biochemical bone marker in relation to bone remodeling after cementless total hip arthroplasty
    Katsuyuki Yamaguchi
    Department of Orthopaedic Surgery, Kaizuka City Hospital, Osaka, Japan
    J Clin Densitom 6:259-65. 2003
    ..422, p = 0.001). We conclude that preoperative bone markers are significant predictors of bone remodeling after THA with the particular implants used in our study...
  95. ncbi High prevalence of asymptomatic vertebral fractures in post-menopausal women receiving chronic glucocorticoid therapy: a cross-sectional outpatient study
    Alberto Angeli
    Internal Medicine, University of Turin, Italy
    Bone 39:253-9. 2006
    ..Vertebral fractures should be looked for carefully in all post-menopausal women receiving long-term systemic GCs since they can be asymptomatic and are scarcely predictable...
  96. ncbi Dual energy X-ray absorptiometry analysis of peri-prosthetic stress shielding in the Birmingham resurfacing hip replacement
    J A Harty
    Department of Orthopaedic Surgery, Cork University Hospital, The Mews, 61 Serpentine Ave, Ballsbridge, Dublin 4, Ireland
    Arch Orthop Trauma Surg 125:693-5. 2005
    ..The aim of this study was to determine the bone mineral density and evidence of stress shielding around the femoral component of the Birmingham resurfacing prosthesis...
  97. pmc Preoperative bone quality as a factor in dual-energy X-ray absorptiometry analysis comparing bone remodelling between two implant types
    Bart Cornelis Hendrikus van der Wal
    Department of Orthopaedic Surgery, Atrium Medical Center, Heerlen, The Netherlands
    Int Orthop 32:39-45. 2008
    ..In future comparative bone remodelling studies using DEXA, patients should be matched for preoperative bone quality and gender...
  98. ncbi Vertebral morphometric X-ray absorptiometry in women with Colles' fracture
    E Kanterewicz
    Rheumatology Unit, Hospital General de Vic, Vic Barcelona, and Universitat Autonoma de Barcelona, Barcelona, Spain
    J Clin Densitom 6:359-66. 2003
    ..By using MXA we found that younger Colles' fracture cases were likely to have more vertebral deformities than healthy controls of the same age range...
  99. ncbi Relationship between soft tissue body composition and bone mass in perimenopausal women
    Suling Li
    Loyola University, Chicago, IL 60153, USA
    Maturitas 47:99-105. 2004
    ..The purpose of this study is to determine the independent effect and relative contribution of lean mass and fat mass to BMD in perimenopausal women...
  100. pmc Proximal femoral structure and the prediction of hip fracture in men: a large prospective study using QCT
    Dennis M Black
    Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California 94107, USA
    J Bone Miner Res 23:1326-33. 2008
  101. ncbi Identification and fracture outcomes of undiagnosed low bone mineral density in postmenopausal women: results from the National Osteoporosis Risk Assessment
    E S Siris
    Toni Stabile Osteoporosis Center, Columbia Presbyterian Medical Center, 180 Fort Washington Ave, New York, NY 10032 3784, USA
    JAMA 286:2815-22. 2001
    ..Large segments of the population at risk for osteoporosis and fracture have not been evaluated, and the usefulness of peripheral measurements for short-term prediction of fracture risk is uncertain...

Research Grants62

  1. Dietary Protein Requirements in Hemodialysis Patients
    Joel Kopple; Fiscal Year: 2007
    ..amino acids, dialysate amino acids, peptides and proteins, and body composition (anthropometry, dual x-ray photon absorptiometry (DXA))...
  2. Salivary-based Bone-loss Marker Detection Platform for Point-of-Care Screening
    MANAL BESHAY; Fiscal Year: 2012
    ..the most reliable methods for bone mineral density (BMD) measurements are imaging techniques such as dual photon absorptiometry (DPA), quantitative computed tomography (QCT), and dual energy X-ray absorptiometry (DEXA)...
    Scott Going; Fiscal Year: 1991
    ..Bone mineral content will be measured using single and dual photon absorptiometry with measurements made at four sites on the forearm, spine and femur giving a better estimate of mineral ..
    Wilson Hayes; Fiscal Year: 1991
    ..Until relatively recently, the most widely accepted screening procedure for osteoporosis was Single Photon Absorptiometry (SPA) to measure bone mineral content (BMC) of the distal radius...
    Richard Boileau; Fiscal Year: 1992
    ..of density (hydrostatic weighing), total body water (deuterium oxide dilution, bone mineral content (photon absorptiometry), and body potassium (40K count)...
    MICHAEL PERTSCHUK; Fiscal Year: 1993
    ..Bone density will be evaluated by means of dual photonabsorpticmetry of the lumbar spine and single photon absorptiometry of the non-dominant mid-radius...
    Lewis Kuller; Fiscal Year: 1991
    ..women we again demonstrated that early age calcium intake is directly related to bone density using dual photon absorptiometry. In a small sample of older postmenopausal women we have found that black women had greater bone density ..
    MaryFran Sowers; Fiscal Year: 1993
    ..Radial and femoral bone mass will be measured by single and dual photon absorptiometry, respectively, at parturition, and following parturition at 2 months, 4 months, 6 months, and 12 months...
    Coralease Ruff; Fiscal Year: 1992
    ..The effects of the treatment will be evaluated in vivo using dual energy photon absorptiometry or quantitative digital radiography, and computed tomography...
    Steven Heymsfield; Fiscal Year: 1990
    ..Using newly developed in vivo methods (dual photon absorptiometry (DPA); delayed-delta, prompt-delta, and inelastic scattering neutron activation) we confirmed these ..
    Peter Snyder; Fiscal Year: 1990
    We propose to quantitate, by dual photon absorptiometry and computed tomography of the lumbar spine, the axial integral and trabecular mineral content in male patients with primary and pituitary hypogonadism, and in patients of both ..
    Michael Kleerekoper; Fiscal Year: 1993
    ..The methods of bone mass measurement (single and dual photon absorptiometry, quantitative densitometric radiography and quantitative computed tomography) permits evaluation of ..
    Robert Marcus; Fiscal Year: 1990 5 anatomic regions (calcaneus, knee, hip, low back, shoulder) will be measured on entry by dual photon absorptiometry, and will be repeated on completion of the study...
    Richard Love; Fiscal Year: 1992
    ..The current proposal is to examine lumbar spine bone mineral density using dual photon absorptiometry, lipoproteins, and several other critical parameters, once, at 4-5 years from entry, in 2 groups of the ..
    Richard Bauer; Fiscal Year: 1992
    ..risk factors for osteoporosis will be assessed by questionnaire and bone mass will be measured by dual photon absorptiometry. These data will be used to identify any differences in-bone mass between Mexican Americans and ..
    Robert Recker; Fiscal Year: 1990
    ..made at three-month intervals throughout the study and bone mass measurements by radio-grammetry, single photon absorptiometry and dual photon absorptiometry will be made at six-month intervals...
    Diane Meier; Fiscal Year: 1991
    ..Utilizing single and dual photon absorptiometry to quantitate appendicular and axial bone mass and measurements of hormonal, physical and nutritional ..
    Harry Genant; Fiscal Year: 1991
    ..Quantitative techniques such as single photon absorptiometry, dual photon absorptiometry, and quantitative computed tomography will be used to assess skeletal status ..
    MITCHELL GOODSITT; Fiscal Year: 1990
    ..The mineral estimates will be compared with those of other CT and photon absorptiometry techniques. The fat estimates will be compared with those of two nuclear magnetic resonance techniques...
  20. 4th International Conference on Children's Bone Health
    Mary Leonard; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  21. Low Magnitude Mechanical Stimuli Effects on Bone Structu
    Mary Leonard; Fiscal Year: 2006
    ..Consistent with the Program Announcement, it is anticipated that this innovative study will lead to a full-scale clinical trial of LMMS as an anabolic bone therapy for ROD in dialysis patients. ..
    Mary Leonard; Fiscal Year: 2006
    Mary Leonard; Fiscal Year: 2005
    ..The accurate characterization of GC and disease effects on skeletal development is necessary to identify and evaluate targeted therapies to optimize skeletal architecture and peak bone mass in childhood. ..
  24. Bone Health in Pediatric Crohn Disease: A Low Magnitude Mechanical Stimulus Trial
    MARY BETH LEONARD; Fiscal Year: 2010
    ..The NIH Osteoporosis Consensus Statement called for studies to identify interventions that promote bone health in children at risk. LMMS may provide a safe and effective treatment for myriad chronic pediatric diseases. ..
  25. Structural Bone Disease in Chronic Renal Insufficiency
    Mary Leonard; Fiscal Year: 2007
    ..Accurate characterization of bone structure in CRI is necessary to identify risk factors for fragility, and to evaluate potential therapies. ..
  26. Vitamin D Deficiency, Physical Performance and Cardiovascular Outcomes in CRIC
    Mary Leonard; Fiscal Year: 2009
    ..Delineation of the relations between 25(OH)D and 1,25(OH)2D and clinical outcomes is necessary in order to develop anticipated randomized trials of vitamin D supplementation in CRI. ..
  27. Exploring Growth Energy Expenditure in Normal-Weight and Overweight Children
    ZiMian Wang; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  28. Vitamin K and Bone in Children with Cerebral Palsy
    CHRISTOPHER MODLESKY; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  29. Flavocoxid: A Medical Food Therapy for Osteoarthritis
    Sarah Morgan; Fiscal Year: 2004
    ..This innovative compound has commercial potential with its expected efficacy comparable to or exceeding the currently marketed COX inhibitors but with fewer side effects and at a significantly lower cost. ..
  30. Forging Implementation of Cancer Screening Reminder Systems (FICSRS)
    Adrianne Feldstein; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  31. Weight in Secondary Prevention (WISP)
    Adrianne Feldstein; Fiscal Year: 2006
    ..Understanding which patients will need the most support to manage weight will allow us to design the most cost-effective future programs. ..
  32. Nutritional and Hormonal Determinants of Peak Bone Mass
    Madhusmita Misra; Fiscal Year: 2008
    ..The effects of estrogen in weight recovered vs. non-weight recovered AN will also be studied. ..
    Barbara Cromer; Fiscal Year: 2003
    ..The statistical analysis will estimate the effect of DMPA on bone density while taking account of constant treatment discontinuation throughout the study period. ..
  34. Ectopic Pregnancy: Assessing Long-Term Trends in Rates and Risk Factors
    Delia Scholes; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  35. Improving Treatment of Newly Diagnosed Osteoporosis
    Peter Cram; Fiscal Year: 2009
    ..Finally, this work will serve as a model for examining the barriers to and improving treatment of other chronic diseases identified through screening. ..
  36. Effects of Alcohol on Urinary Estrogen and Androgen Levels in Women
    Somdat Mahabir; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  37. Fractional flow reserve measurement based on coronary angiographic images
    SABEE Y MOLLOI; Fiscal Year: 2010
    ..This quantification technique could be used to measure fractional flow reserve in patients undergoing standard coronary arteriography. ..
  38. Spectroscopic X-ray Bone Densitometry
    Thomas Beck; Fiscal Year: 2008
    ..The disease is characterized by low bone mass, leading to enhanced bone fragility and a significant increase in the risk of fractures, which is typically diagnosed by bone densitometer [1,2]. [unreadable] [unreadable] [unreadable]..
  39. Oral Contraceptive Use and Bone Density in Young Women
    Delia Scholes; Fiscal Year: 2008
    ..abstract_text> ..
  40. Cardiac care in specialty and general hospitals
    Peter M Cram; Fiscal Year: 2010
    ..Together these analyses will provide much needed information on the relative quality of care provided by specialty cardiac hospitals to policy makers, payors, providers and patients. ..
  41. X-ray imaging using edge-on-microchannel plate detectors
    Sabee Molloi; Fiscal Year: 2006
    ..It can potentially provide a high-resolution detector with significant reduction in patient dose for digital mammography. ..
  42. Dual Energy X-Ray Absorptiometer (QDR4500A)
    Frances Tylavsky; Fiscal Year: 2003
    ..It is within the existing structure and function of the GCRC that the administrative and scientific oversight of this DXA will be managed. ..
  43. Quantification of coronary calcium mass by dual energy fluoroscopy
    Sabee Molloi; Fiscal Year: 2009
    ..Dual-energy imaging, because of its motion insensitivity, can serve as a foundation for quantitative cardiac analysis to proceed. ..
  44. Quantification of Regional coronary Blood Flow
    Sabee Molloi; Fiscal Year: 2003
    ..This quantification technique could be used to measure regional myocardial perfusion in patients undergoing standard coronary arteriography. ..
    Neil Binkley; Fiscal Year: 2003
    ..abstract_text> ..
  46. Biomechanics of Spine Fracture
    TONY KEAVENY; Fiscal Year: 2007
    ..abstract_text> ..
  47. Effect of hormonal contraception on bone mineral density
    Abbey Berenson; Fiscal Year: 2005
    ..Ultimately, this study will determine which women, if any, are placed at increased risk of osteopenia or osteoporosis as a result of using these hormonal contraceptives during their reproductive years. ..
  48. Frequency of aerobic/resistance training in older women
    Gary Hunter; Fiscal Year: 2009
    ..Such information is critical to our understanding of ways to improve well being, quality of life, and independence of an aging population. ..
    TONY KEAVENY; Fiscal Year: 2003
    ..It is suggested that results should lead, therefore, to improved understanding of vertebral fracture etiology, and may motivate development of new drug treatments. ..
    Tony M Keaveny; Fiscal Year: 2010
    ..This project should provide substantial insight into the roles of trabecular bone strength and bone quality on osteoporotic fracture risk and treatment and other orthopedic applications. ..
    Heidi Kalkwarf; Fiscal Year: 2002
    ..Understanding the determinants of this measurement will inform strategies to promote healthy bone and decrease fracture risk in childhood. ..
    Babette Zemel; Fiscal Year: 2003
    ..abstract_text> ..
  53. Change in Bone, Arthritis, Function: Hormones & Obesity
    MaryFran Sowers; Fiscal Year: 2009
  54. Prevalence and Treatment of Hypovitaminosis D in RA
    Karen Hansen; Fiscal Year: 2008
    ..abstract_text> ..
  55. Design of Multiple-Image Radiography of the Breast
    MILES WERNICK; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  56. Microcomputed Tomography Device (Scanco UCT40)
    Mary Bouxsein; Fiscal Year: 2004
    ..abstract_text> ..
  57. Micronutrient Metabolism in HIV+and HIV-Drug Users
    Janet Forrester; Fiscal Year: 2004
    ..The long term goal of this research is to develop effective interventions to improve the nutritional status and health outcomes of drug abusers with and without infectious diseases, including HIV. ..
  58. Depo-provera & BMD: Continuing Observations
    M Clark; Fiscal Year: 2005
    ..The longitudinal design will be continued, maintaining all methods and protocols employed in the parent study. ..
    Anne Newman; Fiscal Year: 2005
    ..abstract_text> ..
    Anne Newman; Fiscal Year: 2007
    ..Accomplishing these goals will provide important information concerning the public health impact of SDB. [unreadable] [unreadable]..