x ray densitometry

Summary

Summary: Measurement of the degree of darkening of X-ray film by means of a photocell which measures light transmission through the film.

Top Publications

  1. ncbi The fracture liaison service: success of a program for the evaluation and management of patients with osteoporotic fracture
    Alastair R McLellan
    Western Infirmary, Glasgow, UK
    Osteoporos Int 14:1028-34. 2003
  2. ncbi Effectiveness of instant vertebral assessment to detect prevalent vertebral fracture
    R D Chapurlat
    Department of Rheumatology and Bone Disease and INSERM Unit 403, Hopital E Herriot, 5 Place d Arsonval, 69437, Lyon, Cedex 03, France
    Osteoporos Int 17:1189-95. 2006
  3. ncbi The prediction of visceral fat by dual-energy X-ray absorptiometry in the elderly: a comparison with computed tomography and anthropometry
    M B Snijder
    Institute for Research in Extramural Medicine, Vrije Universiteit, Amsterdam, The Netherlands
    Int J Obes Relat Metab Disord 26:984-93. 2002
  4. ncbi Serum leptin levels and body composition in postmenopausal women treated with tibolone and raloxifene
    Giovanni A Tommaselli
    Department of Gynecology and Obstetrics, and Pathophysiology of Human Reproduction, University of Naples Federico II, Naples, Italy
    Menopause 13:660-8. 2006
  5. ncbi Relative contribution of lean and fat mass component to bone mineral density in males
    Tsutomu Douchi
    Department of Obstetrics and Gynecology, Faculty of Medicine, Kagoshima University, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    J Bone Miner Metab 21:17-21. 2003
  6. ncbi Bone mass in childhood is related to maternal diet in pregnancy
    J H Tobias
    Clinical Science at South Bristol, Bristol, UK
    Osteoporos Int 16:1731-41. 2005
  7. ncbi Beneficial effect of soy isoflavones on bone mineral content was modified by years since menopause, body weight, and calcium intake: a double-blind, randomized, controlled trial
    Yu Ming Chen
    Department of Community and Family Medicine, School of Pharmacy, The Chinese University of Hong Kong, China
    Menopause 11:246-54. 2004
  8. ncbi Diagnosis of osteoporosis and assessment of fracture risk
    John A Kanis
    WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield S10 2RX, UK
    Lancet 359:1929-36. 2002
  9. pmc Adipose tissue stimulates bone growth in prepubertal children
    E M Clark
    Rheumatology Unit, Bristol Royal Infirmary, Bristol BS2 8HW, United Kingdom
    J Clin Endocrinol Metab 91:2534-41. 2006
  10. ncbi Relation between hormones and body composition, including bone, in prepubertal children
    Sarah P Garnett
    Institute of Endocrinology and Diabetes and the Research and Development Office, The Children s Hospital at Westmead, Westmead, Australia
    Am J Clin Nutr 80:966-72. 2004

Detail Information

Publications276 found, 100 shown here

  1. ncbi The fracture liaison service: success of a program for the evaluation and management of patients with osteoporotic fracture
    Alastair R McLellan
    Western Infirmary, Glasgow, UK
    Osteoporos Int 14:1028-34. 2003
    ....
  2. ncbi Effectiveness of instant vertebral assessment to detect prevalent vertebral fracture
    R D Chapurlat
    Department of Rheumatology and Bone Disease and INSERM Unit 403, Hopital E Herriot, 5 Place d Arsonval, 69437, Lyon, Cedex 03, France
    Osteoporos Int 17:1189-95. 2006
    ....
  3. ncbi The prediction of visceral fat by dual-energy X-ray absorptiometry in the elderly: a comparison with computed tomography and anthropometry
    M B Snijder
    Institute for Research in Extramural Medicine, Vrije Universiteit, Amsterdam, The Netherlands
    Int J Obes Relat Metab Disord 26:984-93. 2002
    ..The aim of the present study is to investigate whether the dual-energy X-ray absorptiometry (DXA) method, possibly combined with anthropometry, offers a good alternative to CT for the prediction of visceral fat in the elderly...
  4. ncbi Serum leptin levels and body composition in postmenopausal women treated with tibolone and raloxifene
    Giovanni A Tommaselli
    Department of Gynecology and Obstetrics, and Pathophysiology of Human Reproduction, University of Naples Federico II, Naples, Italy
    Menopause 13:660-8. 2006
    ..To compare body composition and serum leptin levels in untreated postmenopausal women and postmenopausal women treated with tibolone or raloxifene...
  5. ncbi Relative contribution of lean and fat mass component to bone mineral density in males
    Tsutomu Douchi
    Department of Obstetrics and Gynecology, Faculty of Medicine, Kagoshima University, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    J Bone Miner Metab 21:17-21. 2003
    ..069 and -0.169, respectively). We concluded that, in males, LBM is one of the significant determinants of BMD whereas body fat mass is a negligible BMD determinant...
  6. ncbi Bone mass in childhood is related to maternal diet in pregnancy
    J H Tobias
    Clinical Science at South Bristol, Bristol, UK
    Osteoporos Int 16:1731-41. 2005
    ..Our observation that constituents of maternal diet are related to DXA measures at age 9 is consistent with the hypothesis that the trajectory of bone development in childhood is programmed by early life factors...
  7. ncbi Beneficial effect of soy isoflavones on bone mineral content was modified by years since menopause, body weight, and calcium intake: a double-blind, randomized, controlled trial
    Yu Ming Chen
    Department of Community and Family Medicine, School of Pharmacy, The Chinese University of Hong Kong, China
    Menopause 11:246-54. 2004
    ....
  8. ncbi Diagnosis of osteoporosis and assessment of fracture risk
    John A Kanis
    WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield S10 2RX, UK
    Lancet 359:1929-36. 2002
    ..Many treatments can be provided cost-effectively to men and women if hip fracture probability over 10 years ranges from 2% to 10% dependent on age...
  9. pmc Adipose tissue stimulates bone growth in prepubertal children
    E M Clark
    Rheumatology Unit, Bristol Royal Infirmary, Bristol BS2 8HW, United Kingdom
    J Clin Endocrinol Metab 91:2534-41. 2006
    ..Fat mass represents a positive influence on bone mass in adults, independently of other factors such as lean mass, but whether a similar action occurs in children is unclear...
  10. ncbi Relation between hormones and body composition, including bone, in prepubertal children
    Sarah P Garnett
    Institute of Endocrinology and Diabetes and the Research and Development Office, The Children s Hospital at Westmead, Westmead, Australia
    Am J Clin Nutr 80:966-72. 2004
    ..However, data are lacking that address the extent to which concentrations of these hormones influence body composition, bone mass, and density in prepubertal children...
  11. ncbi Social position affects bone mass in childhood through opposing actions on height and weight
    Emma M Clark
    Community Based Medicine, University of Bristol, United Kingdom
    J Bone Miner Res 20:2082-9. 2005
    ..9 years. The tendency for social position to increase bone area and bone mass through a positive influence on height was opposed by a negative effect of social position on weight and fat mass...
  12. ncbi Effects of cigarette-smoking on bone mass as assessed by dual-energy X-ray absorptiometry and ultrasound
    P Gerdhem
    Department of Orthopaedics, Malmo University Hospital, Malmo, Sweden
    Osteoporos Int 13:932-6. 2002
    ..This difference is detected by DXA but not by ultrasound measurements of the calcaneus or the phalanges. The present data are encouraging since no bone mass differences were found between former and never-smokers...
  13. ncbi Vertebral morphometric X-ray absorptiometry in women with Colles' fracture
    E Kanterewicz
    Rheumatology Unit, Hospital General de Vic, Vic Barcelona, and Universitat Autonoma de Barcelona, Barcelona, Spain
    J Clin Densitom 6:359-66. 2003
    ..By using MXA we found that younger Colles' fracture cases were likely to have more vertebral deformities than healthy controls of the same age range...
  14. ncbi Association between bone mineral density (DXA), body structure, and body composition in middle-aged men
    Leen Van Langendonck
    Department of Sport and Movement Sciences, Faculty of Physical Education and Physiotherapy, KU Leuven, Tervuursevest 101, B 3001 Leuven, Belgium
    Am J Hum Biol 14:735-42. 2002
    ..It is concluded that the principal anthropometric determinant of BMD in middle-aged men is lean mass or muscle...
  15. ncbi One- and two-year change in body composition as measured by DXA in a population-based cohort of older men and women
    Marjolein Visser
    Institute for Research in Extramural Medicine, Vrije University Medical Center, 1081 BT Amsterdam, The Netherlands
    J Appl Physiol 94:2368-74. 2003
    ..Loss of ALST was greater in men compared with women, and greater in blacks compared with whites, suggesting that men and blacks may be more prone to muscle loss...
  16. ncbi Association between dietary conjugated linoleic acid and bone mineral density in postmenopausal women
    Rhonda A Brownbill
    University of Connecticut, Division of Health and Human Development, School of Allied Health, 358 Mansfield Rd, Storrs, CT 06269, USA
    J Am Coll Nutr 24:177-81. 2005
    ..To determine if dietary conjugated linoleic acid (CLA) is associated with bone mineral density (BMD) of different skeletal sites in postmenopausal women...
  17. ncbi Clinical use of bone densitometry: scientific review
    Steven R Cummings
    The UCSF Coordinating Center, University of California, San Francisco, USA
    JAMA 288:1889-97. 2002
    ..Measurement of bone mass by densitometry is a primary part of diagnosing osteoporosis and deciding a preventive treatment course. Bone mineral densitometry has become more widely available and commonly used in practice...
  18. ncbi Identification of vertebral fractures: an update
    L Ferrar
    Bone Metabolism Group, Section of Human Metabolism, Division of Clinical Sciences, University of Sheffield, UK
    Osteoporos Int 16:717-28. 2005
    ..Methods of vertebral fracture definition should be validated by testing the association with clinical outcomes of vertebral fracture, in particular the prediction of incident fractures...
  19. ncbi A comparison study of the reference curves of bone mineral density at different skeletal sites in native Chinese, Japanese, and American Caucasian women
    X P Wu
    Institute of Metabolism and Endocrinology The Second Xiang Ya Hospital, Central South University, Changsha, Hunan 410011, People s Republic of China
    Calcif Tissue Int 73:122-32. 2003
    ..In conclusion, racial differences in BMD reference curves, prevalences, and risks of osteoporosis at various skeletal sites exist among native Chinese, Japanese, and American Caucasian women...
  20. ncbi Device-specific weighted T-score for two quantitative ultrasounds: operational propositions for the management of osteoporosis for 65 years and older women in Switzerland
    D Hans
    Division of Nuclear Medicine, Geneva University Hospital, Geneva, Switzerland
    Osteoporos Int 14:251-8. 2003
    ..The application of this approach will help to minimize the inappropriate use of QUS from which the whole field currently suffers...
  21. ncbi Reliability and accuracy of vertebral fracture assessment with densitometry compared to radiography in clinical practice
    John T Schousboe
    Park Nicollet Clinic, Park Nicollet Health Services, 3800 Park Nicollet Blvd, Minneapolis, MN, 55416, USA
    Osteoporos Int 17:281-9. 2006
    ....
  22. ncbi Are dual-energy X-ray absorptiometry regional estimates associated with visceral adipose tissue mass?
    Y W Park
    Department of Family Medicine, Sungkyunkwan University School of Medicine, Korea
    Int J Obes Relat Metab Disord 26:978-83. 2002
    ..The aim of this study was to evaluate the usefulness of DXA abdominal ROI estimates in assessing VAT among non-obese men...
  23. ncbi Outcomes and secondary prevention strategies for male hip fractures
    Rebecca L Riley
    Veterans Affairs Medical Center, Cincinnati, OH, USA
    Ann Pharmacother 36:17-23. 2002
    ..To assess clinical outcomes and determine whether osteoporosis assessment and secondary prevention strategies were performed for male veterans hospitalized for hip fractures...
  24. ncbi Inhibition of osteoporosis in autoimmune disease prone MRL/Mpj-Fas(lpr) mice by N-3 fatty acids
    Arunabh Bhattacharya
    Division of Clinical Immunology, Department of Medicine, The University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    J Am Coll Nutr 24:200-9. 2005
    ..Anti-inflammatory omega-3 fatty acids may prevent arthritis and bone loss in MRL/lpr mice model of arthritis and in humans...
  25. ncbi Forearm bone mineral density in an unselected population of 2,779 men and women--the HUNT Study, Norway
    Siri Forsmo
    Department of Public Health and General Practice, Norwegian University of Science and Technology, Medisinsk Teknisk Senter, 7489 Trondheim, Norway
    Osteoporos Int 16:562-7. 2005
    ..The accelerated BMD reduction in women aged 50-65 explains the higher prevalence of T-score <-2.5 SD in elderly women than in men. Further studies on bone loss and falls are required to explain the high fracture incidence in Norway...
  26. ncbi Performance of quantitative ultrasound in the discrimination of prevalent osteoporotic fractures in a bone metabolic unit
    F Lopez-Rodriguez
    Bone Metabolic Unit, Endocrinology Division, University Hospital San Cecilio, Granada, Spain
    Bone 32:571-8. 2003
    ..In conclusion, calcaneus ultrasound appears as a useful technique for the routine clinical practice, as its performance is similar to DXA for the discrimination of subjects with osteoporotic fracture...
  27. ncbi Multisite quantitative ultrasound: Colles' fracture discrimination in postmenopausal women
    K M Knapp
    Radiological Sciences, Guy s, Kings and St Thomas Medical School, Guy s Hospital, London, UK
    Osteoporos Int 13:474-9. 2002
    ....
  28. ncbi Congestive heart failure is associated with the rate of bone loss
    K Nishio
    Third Department of Internal Medicine, School of Medicine Showa University, Hatanodai, Shinagawa ku, Tokyo, Japan
    J Intern Med 253:439-46. 2003
    ..To characterize relationships between mineral homeostasis, bone turnover, bone mass, and congestive heart failure (CHF), we evaluated 75 women with mild to moderate CHF...
  29. ncbi Exercise frequency and calcium intake predict 4-year bone changes in postmenopausal women
    Ellen C Cussler
    Department of Physiology, University of Arizona, Tucson, AZ, USA
    Osteoporos Int 16:2129-41. 2005
    ..The positive relationship of CI to change in BMD among postmenopausal women not using HT has clinical implications in light of recent evidence of an increased health risk associated with HT...
  30. ncbi The prevalence of significant left-right differences in hip bone mineral density
    R Hamdy
    Osteoporosis Center, College of Medicine, East Tennessee State University and VAMC, Johnson City, TN, USA
    Osteoporos Int 17:1772-80. 2006
    ....
  31. ncbi Change in lean body mass is a major determinant of change in areal bone mineral density of the proximal femur: a 12-year observational study
    T Liu-Ambrose
    UBC Bone Health Research Group Centre for Hip Health, BC Women s Hospital and Health Centre Osteoporosis Program, and Faculty of Medicine, University of British Columbia, 828 West 10th Avenue, Vancouver, BC, Canada, V5Z 1L8
    Calcif Tissue Int 79:145-51. 2006
    ..These novel longitudinal data highlight the important contribution of LBM to the maintenance of proximal femur bone mass at a key time in women's life span, the years surrounding menopause...
  32. ncbi Soft tissue composition, axial bone mineral density, and grip strength in postmenopausal Turkish women with early rheumatoid arthritis: Is lean body mass a predictor of bone mineral density in rheumatoid arthritis?
    Gunsah Sahin
    Mersin University, Faculty of Medicine, Department of PMR, Mersin, Turkey
    Int J Fertil Womens Med 51:70-4. 2006
    ..To study bone mineral density and body composition in patients with early rheumatoid arthritis to determine the relationship of lean mass, fat mass and hand grip strength to bone mineral density...
  33. ncbi Relationships between bone mineral density, insulin-like growth factor-1 and sex hormones in young females with different physical activity
    T Soot
    Sport Pedagogy Unit, Centre of Behavioural and Health Sciences, Faculty of Exercise and Sport Sciences, University of Tartu, Tartu, Estonia
    J Sports Med Phys Fitness 46:293-7. 2006
    ..To study the possible relationships between bone mineral density (BMD) and blood concentrations of estradiol, progesterone and IGF-1 in strength and endurance trained and sedentary normal or overweight young females...
  34. ncbi Girls on a high-calcium diet gain weight at the same rate as girls on a normal diet: a pilot study
    Joan M Lappe
    Osteoporosis Research Center, Creighton University, 601 N 30th Street, Omaha, NE 68131, USA
    J Am Diet Assoc 104:1361-7. 2004
    ..To determine whether pubertal girls assigned to calcium-rich diets or their usual calcium intakes differ significantly in weight gain...
  35. ncbi Maturity and activity-related differences in bone mineral density: Tanner I vs. II and gymnasts vs. non-gymnasts
    Jodi N Dowthwaite
    Department of Orthopedic Surgery, State University of New York Upstate Medical University, 550 Harrison St, Suite 128, Syracuse, NY 13202, USA
    Bone 39:895-900. 2006
    ..Overall, aBMD correlations and ANCOVA results differ by activity group, maturity level and site. These results highlight the need to consider both maturity and activity status in studies assessing bone accrual...
  36. ncbi Peri-prosthetic bone mineral density after total knee arthroplasty. Cemented versus cementless fixation
    R B Abu-Rajab
    Orthopaedic Department, Diabetes Centre, Southern General Hospital, 1345 Govan Road, Glasgow G51 4TF, Scotland, UK
    J Bone Joint Surg Br 88:606-13. 2006
    ..However, both produce stress-shielding around the femoral implants. This leads us to question the use of more expensive cementless total knee components...
  37. ncbi Ability of peripheral DXA measurement to diagnose osteoporosis as assessed by central DXA measurement
    D Picard
    Department of Nuclear Medicine, Hopital Saint Luc, Universite de Montreal, Montreal, Quebec, Canada
    J Clin Densitom 7:111-8. 2004
    ....
  38. ncbi Serum leptin levels in childhood celiac disease
    Vildan Ertekin
    Divisions of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Faculty of Medicine, Ataturk University, Erzurum, Turkey
    J Clin Gastroenterol 40:906-9. 2006
    ..We thought that with its intestinal histopathologic alterations due to immune mechanisms, and subsequent malnutrition and/or growth failure, celiac disease (CD) deserves interest regarding leptin status...
  39. ncbi Apparent bone mineral density estimated from DXA in healthy men and women
    Selma Cvijetic
    Center for Osteoporosis, Institute for Medical Research and Occupational Health, Ksaverska cesta 2, Zagreb, Croatia
    Osteoporos Int 15:295-300. 2004
    ..Weaker association of body height and weight with BMAD than with BMD suggests that BMD depends on the bone size and body size and that the different BMDs could be the consequence of the difference in those parameters...
  40. ncbi [Influence of glucocorticoids on bone mineral density in rheumatoid arthritis and seronegative spondyloarthropathies]
    Asta Savickiene
    Clinic of Rheumatology, Kaunas University of Medicine, Lithuania
    Medicina (Kaunas) 39:448-53. 2003
    ..Diminishing of the bone mineral density was more important in the lumbar spine, the changes in hip mineralization were less expressed in both diseases...
  41. ncbi [Bone mineral density in healthy Lithuanian women]
    Vidmantas Alekna
    Center of Gerontology and Rehabilitation, Institute of Experimental and Clinical Medicine, Vilnius University, Lithuania
    Medicina (Kaunas) 39:498-504. 2003
    ..The purposes of this investigation were to determine spine and femoral bone mineral density for a representative sample of healthy women of Lithuanian descent and to compare these results with US/European reference data...
  42. ncbi Can radial bone mineral density and quantitative ultrasound measurements reduce the number of women who need axial density skeletal assessment?
    J Damilakis
    Department of Medical Physics, Faculty of Medicine, University of Crete, PO Box 1393, 71409 Iraklion, Crete, Greece
    Osteoporos Int 14:688-93. 2003
    ..SOS of the phalanges and radius appears to have less value in the detection of the women with low axial BMD...
  43. ncbi Decreased bone mineral density in HIV-infected patients is independent of antiretroviral therapy
    Dario Bruera
    Endocrinology Department, Hospital Nacional de Clinicas, Medical Science School, National University of Cordoba, Cordoba, Argentina
    AIDS 17:1917-23. 2003
    ..To describe the alterations in the bone metabolism of HIV-seropositive patients and evaluate the effects of antiretroviral therapies...
  44. ncbi Bone mineral density and fractures in Turner syndrome
    Vladimir K Bakalov
    Developmental Endocrinology Branch, National Institute of Child Health, Bethesda, Maryland 20892, USA
    Am J Med 115:259-64. 2003
    ..To determine whether women with Turner syndrome who were treated with estrogen were more likely to have osteoporosis and fractures...
  45. ncbi Definition of a population-specific DXA reference standard in Italian women: the Densitometric Italian Normative Study (DINS)
    M Pedrazzoni
    Dipartimento di Medicina Interna e Scienze Biomediche, Universita di Parma, Via Gramsci 14, 43100, Parma, Italy
    Osteoporos Int 14:978-82. 2003
    ..16%) or osteopenic (42 vs. 38%) compared to DINS...
  46. ncbi Evaluation of bone metabolism in children with acute lymphoblastic leukemia after induction chemotherapy treatment
    Fani Athanassiadou
    2nd Pediatric Department Hematology Oncology Unit, AHEPA Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Pediatr Hematol Oncol 22:285-9. 2005
    ..Since a reduced BMD predisposes to osteopenia and osteoporosis, specific attention and therapeutic interventions should be considered...
  47. ncbi [Effect of progressive insulin resistance on the correlation of glucose metabolism and bone status]
    Barbara Buday
    DRC Kft, Balatonfured
    Orv Hetil 148:1127-33. 2007
    ..Decreasing insulin sensitivity of bones and escape from "metabolic control" may result in frequently observed hyperdensity in Type 2 diabetics...
  48. ncbi Bone mass density in adults with sickle cell disease
    Mona Sarrai
    The Comprehensive Sickle Cell Thalassemia Program and the Department of Medicine, New York Methodist Hospital, Brooklyn, NY, USA
    Br J Haematol 136:666-72. 2007
    ..In this SCD population, abnormal BMD seemed to be independent of sex, age and menopause, whereas BMI, ferritin level, Hb type and level appeared to play a major role...
  49. ncbi Supplementation with oral vitamin D3 and calcium during winter prevents seasonal bone loss: a randomized controlled open-label prospective trial
    Christian Meier
    Bone Research Program, ANZAC Research Institute, University Sydney, Concord, New South Wales, Australia
    J Bone Miner Res 19:1221-30. 2004
    ..Supplementation with oral vitamin D3 and calcium during the winter months seems to counteract the effects of seasonal changes in vitamin D and thus may be beneficial as a primary prevention strategy for age-related bone loss...
  50. ncbi The relation between joint erosion and generalized osteoporosis and disease activity in patients with rheumatoid arthritis
    Filiz Sivas
    Ankara Numune Education and Research Hospital, Clinic of Physical Medicine and Rehabilitation, Ankara, Turkey
    Rheumatol Int 26:896-9. 2006
    ....
  51. ncbi Dissociation between global markers of bone formation and direct measurement of spinal bone formation in osteoporosis
    Michelle L Frost
    Osteoporosis Screening and Research Unit, Guy s, King s, and St Thomas School of Medicine, King s College, London, United Kingdom
    J Bone Miner Res 19:1797-804. 2004
    ..Lower values of regional bone formation activity at the lumbar spine were seen in osteoporotic women, whereas global markers of bone formation were significantly increased...
  52. ncbi The development of bone mineral density and the occurrence of osteoporosis from 15 to 20 years of disease onset in patients with rheumatoid arthritis
    H Hamalainen
    The Rheumatism Foundation Hospital, Heinola, Finland
    Clin Exp Rheumatol 23:193-8. 2005
    ..BMD measurements were obtained at the 15- and 20-year follow-up visits...
  53. ncbi Osteoporosis in diffuse parenchymal lung disease
    Caralee E Caplan-Shaw
    Department of Medicine, Columbia University College of Physicians and Surgeons, Mount Sinai School of Medicine, New York, NY 10032, USA
    Chest 129:140-6. 2006
    ..We hypothesized that patients with DPLD referred for lung transplantation would have a high prevalence of osteoporosis related to corticosteroid use or reduced pulmonary function and exercise capacity...
  54. ncbi Bone mineral density and its correlation with clinical and laboratory factors in chronic peritoneal dialysis patients
    Fettah Fevzi Ersoy
    Division of Nephrology, Department of Medicine, Akdeniz University Medical School, 07070 Dumlupinar Bulvari, Kampus, Antalya, Turkey
    J Bone Miner Metab 24:79-86. 2006
    ..An insufficient dialysis dose (expressed as KT/V) and older age may also be important risk factors for osteoporosis of PD patients...
  55. ncbi Bone status of Indian women from a low-income group and its relationship to the nutritional status
    Veena Shatrugna
    National Institute of Nutrition, Indian Council of Medical Research, Jamai Osmania P O, 500 007, Hyderabad, India
    Osteoporos Int 16:1827-35. 2005
    ..05). In addition to these, height was also an important determinant of WB-BMC. This study highlights the urgent need for measures to improve the nutritional status, dietary calcium intake and thus the bone health of this population...
  56. pmc Bone mineral density, body mass index and cigarette smoking among Iranian women: implications for prevention
    Azam Baheiraei
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, University of New South Wales, Sydney, Australia
    BMC Musculoskelet Disord 6:34. 2005
    ..This study was designed to estimate the modifiable distribution and determinants of bone mineral density (BMD) among Iranian women in Australia...
  57. ncbi [Role of osteoporosis in trauma diagnostics]
    H Bitterling
    Klinikum der LMU, Institut fur Klinische Radiologie, Innenstadt, Munchen
    Rofo 177:1663-9. 2005
    ..To evaluate the current bone mineral density (BMD) distribution in elderly patients hospitalized due to traumatic hip fracture and to assess the necessity of concomitant pharmacotherapy of underlying osteoporosis...
  58. ncbi Prevalence of low central bone mineral density in a Bulgarian female referral population: a pilot study
    Mihail A Boyanov
    Endocrinology Clinic, Alexandrovska Hospital, Medical University of Sofia, 1, G Sofiiski str, Sofia, 1431, Bulgaria
    Rheumatol Int 26:523-9. 2006
    ..74% at the spine and in 65.57% at the total hip. This is the first Bulgarian study looking for the prevalence of central osteoporosis in a female referral population. It may become the starting point for future epidemiological work...
  59. ncbi Modulation of bone turnover by alfacalcidol and/or alendronate does not prevent glucocorticoid-induced osteoporosis in growing minipigs
    Shojiro Akahoshi
    Department of Orthopaedic Surgery, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan
    J Bone Miner Metab 23:341-50. 2005
    ..Modulation of bone tissue turnover by alfacalcidol and/or alendronate failed to maintain the growth-dependent increases in mass and structure in GC-treated young minipigs...
  60. ncbi Effect of growth hormone therapy and puberty on bone and body composition in children with idiopathic short stature and growth hormone deficiency
    Wolfgang Hogler
    Institute of Endocrinology and Diabetes, The Children s Hospital at Westmead, Locked Bag 4001, NSW 2145, Sydney, Australia
    Bone 37:642-50. 2005
    ..Growth hormone had great effects on the growth plate and body composition with subsequent gains in height, LTM, bone turnover, and bone mass accrual, but no benefit for volumetric bone density over 2 years...
  61. ncbi Contribution of lean tissue mass to the urban-rural difference in bone mineral density
    Chatlert Pongchaiyakul
    Department of Endocrinology, Khon Kaen University Medical School, Khon Kaen, Thailand
    Osteoporos Int 16:1761-8. 2005
    ..These data are thus consistent with the hypothesis that the urban-rural difference in BMD at a weight-bearing site is in part associated with the urban-rural difference in lean mass...
  62. ncbi Bone mineral density in Iranian patients with inflammatory bowel disease
    Mohammadreza Zali
    Department of Inflammatory Bowel Disease, Research Center for Gastroenterology and Liver Diseases, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Int J Colorectal Dis 21:758-66. 2006
    ..Treatment with corticosteroid has increased this possibility in both groups. Corticosteroid use, age, smoking, and BMI are predictive factors for low bone density...
  63. ncbi Daily physical education in the school curriculum in prepubertal girls during 1 year is followed by an increase in bone mineral accrual and bone width--data from the prospective controlled Malmö pediatric osteoporosis prevention study
    O Valdimarsson
    Clinical and Molecular Osteoporosis Research Unit, Department of Clinical Sciences, Lund University, Malmo University Hospital, Malmo SE 205 02, Sweden
    Calcif Tissue Int 78:65-71. 2006
    ..The annual gain in bone width was 2.9 percentage points higher in L3 in cases than in controls (P < 0.001). A general school-based exercise program in girls aged 7-9 years enhances the accrual of BMC and aBMD and increases bone width...
  64. ncbi [Clinical trial for differentiation between corticoid-induced osteoporosis and periarticular demineralization via digital radiogrammetry in patients suffering from rheumatoid arthritis]
    J Bottcher
    Institut für Diagnostische und Interventionelle Radiologie, Friedrich Schiller Universitat Jena, Erlanger Allee 101, 07747 Jena, Germany
    Z Rheumatol 63:473-82. 2004
    ....
  65. ncbi Use of the lowest vertebral body T-score to diagnose lumbar osteoporosis in men: is "cherry picking" appropriate?
    Karen E Hansen
    Rheumatology Section, Department of Medicine, University of Wisconsin, Madison, WI and Veterans Hospital, Madison, WI 53750, USA
    J Clin Densitom 7:376-81. 2004
    ..Prospective studies are needed to determine which of these three methods of lumbar spine analysis best predicts future fragility fracture in men and women...
  66. ncbi Both resistance and agility training increase cortical bone density in 75- to 85-year-old women with low bone mass: a 6-month randomized controlled trial
    Teresa Y L Liu-Ambrose
    UBC Bone Health Research Group, BC Women s Hospital and Health Centre Osteoporosis Program, Centre for Hip Health, and Faculty of Medicine, School of Human Kinetics, University of British Columbia, Vancouver, BC, Canada
    J Clin Densitom 7:390-8. 2004
    ..Future research is needed to determine the mechanism(s) responsible for the observed adaptation of the cortical bone to mechanical loading...
  67. ncbi Reproducibility of fan-beam DXA measurements in adults and phantoms
    Kenneth J Ellis
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
    J Clin Densitom 7:413-8. 2004
    ..Comparisons based solely on the use of a spine phantom are insufficient to ensure compatibility of human bone mineral data at other bone sites or for the whole body...
  68. ncbi Recalculation of the NHANES database SD improves T-score agreement and reduces osteoporosis prevalence
    Neil Binkley
    University of Wisconsin Osteoporosis Clinical Center and Research Program, Madison, Wisconsin, USA
    J Bone Miner Res 20:195-201. 2005
    ..Use of a recalculated young-normal SD for the GE Lunar-adjusted NHANES III database improved diagnostic agreement and is recommended...
  69. ncbi Umbilical cord leptin predicts neonatal bone mass
    M K Javaid
    MRC Epidemiology Resource Centre, University of Southampton, Soumampton General Hospital, Southampton, SO16 6YD, UK
    Calcif Tissue Int 76:341-7. 2005
    ..In addition, among previously documented maternal determinants of neonatal bone mass in healthy pregnancies, maternal fat stores may mediate their effect on fetal bone accrual through variation in fetal leptin concentrations...
  70. ncbi The ability of peripheral quantitative ultrasound to identify patients with low bone mineral density in the hip or spine
    R B Cook
    Department of Materials and Medical Sciences, Cranfield University Postgraduate Medical School, Shrivenham SN6 8LA, UK
    Ultrasound Med Biol 31:625-32. 2005
    ..Cut-off values varied according to the technique used and the accuracy of the screening required. Assessment of the calcaneus was the best QUS technique for the prediction of low bone density at the axial skeleton as diagnosed by DXA...
  71. ncbi Effects of alendronate on bone mineral density and bone metabolic markers in patients with liver transplantation
    F Atamaz
    Department of Physical Therapy and Rehabilitation, Medical Faculty of Ege University, Bornova Izmir, Turkey
    Osteoporos Int 17:942-9. 2006
    ..The purpose of this study was to evaluate the effects of alendronate (ALN) on bone mineral density (BMD) and bone turnover markers in patients with orthotopic liver transplantation (OLT)...
  72. ncbi High-dose glucocorticoid treatment induces rapid loss of trabecular bone mineral density and lean body mass
    Koshi Natsui
    Department of Medicine, Fukui Red Cross Hospital, 4 2 1 Tsukimi, 918 8501, Fukui, Japan
    Osteoporos Int 17:105-8. 2006
    ..Decreased LBM might be also responsible for the increased risk of fracture, since falling is a well-known risk factor for fracture, and patients receiving glucocorticoid treatment should also be evaluated for their body composition...
  73. ncbi A new selective estrogen receptor modulator, CHF 4227.01, preserves bone mass and microarchitecture in ovariectomized rats
    Reina Armamento-Villareal
    Division of Bone and Mineral Diseases, Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    J Bone Miner Res 20:2178-88. 2005
    ..01, given to 6-month-old female rats immediately after ovariectomy, preserved bone mass and bone microarchitecture without affecting uterus weight. It also decreased serum cholesterol and fat mass in estrogen-deficient rats...
  74. ncbi Comparison of imaging-guided and non-imaging-guided quantitative sonography of the calcaneus with dual X-ray absorptiometry of the spine and femur
    F M Lomoschitz
    Department of Radiology, University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    AJR Am J Roentgenol 180:1111-6. 2003
    ..The purpose of our study was to evaluate the diagnostic agreement between imaging-guided and non-imaging-guided quantitative sonography of the calcaneus and dual X-ray absorptiometry of the spine and femur to show osteoporosis...
  75. ncbi Changes in bone mineral density, lean body mass and fat content as measured by dual energy x-ray absorptiometry in patients with prostate cancer without apparent bone metastases given androgen deprivation therapy
    Alfredo Berruti
    Department of Clinical and Biological Sciences, University of Torino at San Luigi Hospital, Orbassano, Italy
    J Urol 167:2361-7; discussion 2367. 2002
    ..We characterize the consequences of androgen deprivation therapy on body composition in elderly men...
  76. ncbi Dual energy X-ray absorptiometry outcomes in male COPD patients after treatment with different glucocorticoid regimens
    Emile F Dubois
    Department of Pulmonary Diseases, Reinier de Graaf Groep Delft and Voorburg, The Netherlands
    Chest 121:1456-63. 2002
    ..To compare bone mineral density (BMD) outcomes of patients who received continuous oral systemic glucocorticoids (GCs) with BMD outcomes of patients who received multiple GC courses, oral or IV...
  77. ncbi Bone mineral density and quantitative ultrasound in adults with cystic fibrosis
    F Flohr
    Department of Internal Medicine II, Division of Endocrinology, University Hospital of Freiburg, Freiburg, Germany
    Eur J Endocrinol 146:531-6. 2002
    ..3 years) was to assess the prevalence of low bone mineral density (BMD) by dual-energy x-ray absorptiometry (DEXA) and, for the first time, by quantitative ultrasound (QUS), and to identify predicting factors...
  78. ncbi Normative data of bone mineral density in an unselected adult Austrian population
    S Kudlacek
    Krankenhaus der Barmherzigen Bruder, Vienna, Austria
    Eur J Clin Invest 33:332-9. 2003
    ..We therefore collected data on age-related BMD in a random sample of the normal adult Austrian population to establish an appropriate normative database...
  79. ncbi A longitudinal analysis of sex differences in bone mineral accrual in healthy 8-19-year-old boys and girls
    A D G Baxter-Jones
    College of Kinesiology, University of Saskatchewan, Saskatoon, Canada
    Ann Hum Biol 30:160-75. 2003
    ..It is uncertain if these differences represent differences in bone mass or just differences in anthropometric dimensions...
  80. ncbi A prospective study of discordance in diagnosis of osteoporosis using spine and proximal femur bone densitometry
    D O'Gradaigh
    Bone Research Group, Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke s Hospital, Hills Road, Cambridge, CB2 2QQ, UK
    Osteoporos Int 14:13-8. 2003
    ..We conclude that, as the most usual indication for bone densitometry is to aid the determination of an individual's fracture risk, both proximal femur and lumbar spine should continue to be assessed...
  81. ncbi Lactose intolerance: a risk factor for reduced bone mineral density and vertebral fractures?
    Stefan Kudlacek
    KH Barmherzige Brüder, Medizinische Abteilung, Vienna, Austria
    J Gastroenterol 37:1014-9. 2002
    ..The purpose of the present study was to determine differences, if any, in bone mineral density, the risk of fracture, and clinical behavior in patients with lactose intolerance investigated by hydrogen breath test...
  82. ncbi Bone strength at clinically relevant sites displays substantial heterogeneity and is best predicted from site-specific bone densitometry
    Felix Eckstein
    Musculoskeletal Research Group, Institute of Anatomy, Ludwig Maximilians Universitat Munchen, Munich, Germany
    J Bone Miner Res 17:162-71. 2002
    ..These data suggest that mechanical competence in the elderly is governed by strong regional variation, and that its loss in osteoporosis may not represent a strictly systemic process...
  83. ncbi Bone mineral density in young women of the city of São Paulo, Brazil: correlation with both collagen type I alpha 1 gene polymorphism and clinical aspects
    E R Barros
    Disciplina de Endocrinologia, Setor de Doença Osteo Metabólica, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brasil
    Braz J Med Biol Res 35:885-93. 2002
    ..041). There was no association between the presence of allele s and reduced BMD. We conclude that a family history of osteoporosis and age at menarche are factors that may influence bone mass in our population...
  84. ncbi Prevalence of osteoporotic bone mineral density at the hip in Britain differs substantially from the US over 50 years of age: implications for clinical densitometry
    G Holt
    Department of Medicine Box 157, Clinical Gerontology and the Institute of Public Health, Clinical School, Hills Road, University of Cambridge, UK
    Br J Radiol 75:736-42. 2002
    ..Providing that the relationship between fracture rates and BMD is the same in Britain and the US, it would still be appropriate to apply the reference data in fracture risk assessment in the UK...
  85. ncbi Corticosteroid-induced osteoporosis: does it occur in patients with Crohn's disease?
    D J de Jong
    Department of Gastroenterology, University Medical Center Nijmegen, The Netherlands
    Am J Gastroenterol 97:2011-5. 2002
    ..In Crohn's disease, osteoporosis is frequently found. However, the etiology of osteoporosis remains unclear. The aim of this study was to determine disease-related variables predictive for impaired bone mineral density (BMD)...
  86. ncbi Bone mineral density in long-term survivors of highly malignant osteosarcoma
    G Holzer
    Department of Orthopaedics, Vienna General Hospital, Vienna, Austria
    J Bone Joint Surg Br 85:231-7. 2003
    ..Ten patients were osteoporotic, 21 osteopenic and 17 normal according to the WHO definition. Eighteen patients suffered fractures after receiving chemotherapy and all had significantly lower levels of BMD for all the sites measured...
  87. ncbi Intergenerational comparison of total and regional bone mineral density and soft tissue composition in Japanese women without vertebral fractures
    Shinjiro Takata
    Department of Orthopedics, The University of Tokushima School of Medicine, Japan
    J Med Invest 49:142-6. 2002
    ..The results showed that the decrease in BMD of the spine and pelvis was the most prominent of all regional BMDs associated with a decrease in the total and regional lean mass and total and regional fat mass...
  88. ncbi Bone mineral density in premenopausal women with major depressive disorder
    Kazim M Yazici
    Hacettepe University Faculty of Medicine, Department of Psychiatry, Ankara 06100, Turkey
    Psychiatry Res 117:271-5. 2003
    ..In conclusion, depressed women may have decreased BMD even at the very early stages of the illness, and this possibility should be taken into consideration in treatment...
  89. pmc Relationships between endothelial nitric oxide synthase gene polymorphisms and osteoporosis in postmenopausal women
    Shun zhi Liu
    Department of Public Health, School of Medicine, Xi an Jiaotong University, Xi an 710061, China
    J Zhejiang Univ Sci B 10:609-18. 2009
    ..To investigate the relationships between endothelial nitric oxide synthases (eNOS) G894T and 27 bp-variable number tandem repeat (VNTR) gene polymorphisms and osteoporosis in the postmenopausal women of Chinese Han nationality...
  90. ncbi Correlates of low bone density in females with anorexia nervosa
    Marcie Schneider
    Division of Adolescent Medicine, Department of Pediatrics, North Shore University Hospital, New York University School of Medicine, Manhasset, New York, USA
    Int J Adolesc Med Health 14:297-306. 2002
    ..The objectives were to delineate those factors which correlate with low bone density in patients with anorexia nervosa and in turn to predict those at greatest risk for osteopenia...
  91. ncbi Black hole artifacts-a new potential pitfall for DXA accuracy?
    Sarah L Morgan
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294 1270, USA
    J Clin Densitom 11:266-75. 2008
    ..Attention should be paid to the possibility of black hole artifacts on DXA scans and the effect they may have on spine results. Viewing scans in the single-energy mode can be used to verify the presence of tantalum clips...
  92. ncbi Cortisol metabolism in human obesity: impaired cortisone-->cortisol conversion in subjects with central adiposity
    P M Stewart
    Endocrinology, Division of Medical Sciences, University of Birmingham, Queen Elizabeth Hospital, Edgbaston, United Kingdom
    J Clin Endocrinol Metab 84:1022-7. 1999
    ..This reduction in 11betaHSD1 activity raises new questions as to the primary role of 11betaHSD1 in the pathogenesis of insulin resistance and central obesity...
  93. ncbi Beneficial effect of copper supplementation on deposition of fluoride in bone in fluoride- and molybdenum-fed rabbits
    A L Khandare
    National Institute of Nutrition, Jamai Osmania, Hyderabad, India
    Calcif Tissue Int 77:233-8. 2005
    ..The increase in F level due to Mo addition appears to be offset by supplementation with Cu. Supplementation with Cu showed a beneficial effect on bone resorption as well as bone formation...
  94. ncbi Effect of long-term impact-loading on mass, size, and estimated strength of humerus and radius of female racquet-sports players: a peripheral quantitative computed tomography study between young and old starters and controls
    Saija Kontulainen
    The Bone Research Group, UKK Institute for Health Promotion Research, Tampere, Finland
    J Bone Miner Res 18:352-9. 2003
    ....
  95. ncbi Bone geometry and density in the skeleton of pre-pubertal gymnasts and school children
    K A Ward
    Clinical Radiology, Imaging Science and Biomedical Engineering, Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Bone 36:1012-8. 2005
    ..In conclusion, the present study has demonstrated skeletal differences between gymnasts and controls. These differences appear to be site and sex specific...
  96. ncbi Predicting the integrity of vertebral bone screw fixation in anterior spinal instrumentation
    B D Snyder
    Department of Orthopaedic Surgery, Harvard Medical School, Children s Hospital, Boston, Massachusetts, USA
    Spine (Phila Pa 1976) 20:1568-74. 1995
    ..A bicortical screw inserted through a Dwyer-type staple provided the strongest and most rigid form of fixation...
  97. ncbi An evaluation of sex and body weight determination from the proximal femur using DXA technology and its potential for forensic anthropology
    Bruce P Wheatley
    Department of Anthropology, University of Alabama at Birmingham, Birmingham, AL 35294 3350, USA
    Forensic Sci Int 147:141-5. 2005
    ..DXA technology offers the potential of a living skeletal data bank and of variables that are useful in cause-effect relationships between bone mineralization and skeletal loads...
  98. ncbi Association between a functional interleukin-6 gene polymorphism and peak bone mineral density and postmenopausal bone loss in women: the OFELY study
    P Garnero
    INSERM Research Unit 403, Hopital E Herriot, Lyon, France
    Bone 31:43-50. 2002
    ..Larger long-term studies are necessary to assess adequately the relationships between IL-6 genotype, rate of bone loss, and risk of fracture...
  99. ncbi Effects of long-lasting raloxifene treatment on serum prolactin and gonadotropin levels in postmenopausal women
    A Lasco
    Department of Internal Medicine, Section of Endocrinology, University of Messina, Messina, Italy
    Eur J Endocrinol 147:461-5. 2002
    ....
  100. ncbi Effects of nail rigidity on fracture healing. Strength and mineralisation in rat femoral bone
    S E Utvåg
    Department of Orthopedics, University Hospital, Tromsoe, Norway
    Arch Orthop Trauma Surg 118:7-13. 1998
    ..BMD in the callus region was also highest after titanium nailing at 12 weeks. BMD in the distal diaphysis and total femur indicates that the degree of stiffness of the nails have little influence on total bone mineralisation at 12 weeks...
  101. ncbi A prospective study of bone loss and turnover after cardiac transplantation: effect of calcium supplementation with or without calcitonin
    M J Valimaki
    Department of Medicine, University of Helsinki, Finland
    Osteoporos Int 10:128-36. 1999
    ..High bone turnover underlies bone loss after cardiac transplantation. Bone loss is most rapid during the first 6 post-transplant months. In the upper femur this bone loss may be reduced by treatment with calcium and calcitonin...

Research Grants73

  1. METABOLIC SYNDROME AND PERIODONTITIS IN POSTMENOPAUSAL WOMEN
    Michael J LaMonte; Fiscal Year: 2013
    ..The existing resources for this secondary data analysis provide an unprecedented cost- efficient opportunity to build on established work and expand knowledge in this important area of public health. ..
  2. Novel, Rapidly Translatable Technologies for Healing Long Bone Segmental Defects
    Christopher H Evans; Fiscal Year: 2010
    ..If this project is successful, it will prevent much human suffering, enable people to return to work more quickly, and save money. ..
  3. Effects of Gastric Bypass Surgery on Calcium Metabolism and the Skeleton
    ANNE LOUISE SCHAFER; Fiscal Year: 2013
    ..Dr. Schafer is committed to improving the health care of veterans through clinical research, and the CDA-2 is critical for the attainment of her career objectives. ..
  4. Effect of Adrenal and Gonadal Hormones on Bone Marrow and Appendicular BMD
    Catherine M Gordon; Fiscal Year: 2013
    ..Knowledge gained from this study may also have application to other diseases across the age spectrum that are associated with bone loss and involve alterations in bone marrow composition. ..
  5. Salivary-based Bone-loss Marker Detection Platform for Point-of-Care Screening
    MANAL BESHAY; Fiscal Year: 2012
    ..Significant cost savings will be realized in the reduction of osteoporosis-related fractures and associated treatment. ..
  6. Secondary Muscle Pathology &Metabolic Dysregulation in Adult with Cerebral Palsy
    Mark Peterson; Fiscal Year: 2013
    ..Burant and Gordon, and faculty of the MNORC to learn various immunohistochemical procedures. Throughout the entirety of training, the candidate will also work with Dr. Spino for data management and biostatistical expertise. ..
  7. Assessment of Bone Composition Through a Novel Liquid/Solid State MRI Method
    Ara Nazarian; Fiscal Year: 2013
    ..abstract_text> ..
  8. Assessment of Bone Composition Through a Novel Liquid/Solid State MRI Method
    Ara Nazarian; Fiscal Year: 2011
    ....
  9. RYGB Improves Metabolism by Interrupting the Gastric Adipose Tissue Axis
    Naji N Abumrad; Fiscal Year: 2013
    ..The information derived could lead to the combination of less invasive surgical procedures with pharmacologic manipulation of the levels of acylated ghrelin and/or leptin for the treatment of morbid obesity. ..
  10. Effect of Perinatal Diet on Developmental Programming of the Skeleton
    Mary L Bouxsein; Fiscal Year: 2010
    ..Establishing that maternal / perinatal diet influences peak bone mass acquisition may point to diet as a modifiable risk factor for adult bone disease. ..
  11. Mechanisms for the Effects of Hypothalamic PTP1B on Energy Balance
    KARYN JOANNE CATALANO; Fiscal Year: 2010
    ..By attempting to determine the specific neurons critical in these pathways, we hope to bring research closer to developing effective treatments for obesity with minimal side effects. ..
  12. Vitamin D and Vascular Function in Obese Children
    Kumaravel Rajakumar; Fiscal Year: 2013
    ....
  13. Adiposity and Outcomes of Clinically Localized Prostate Cancer
    Vincent L Freeman; Fiscal Year: 2013
    ..It will also shed light on ways to prevent prostate cancer recurrence that may involve new or existing medicines or lifestyle changes. ..
  14. Prenatal stress biology, infant body composition and obesity risk
    Sonja Entringer; Fiscal Year: 2013
    ..abstract_text> ..
  15. CYP19A1 gene and Pharmacogenetics of Response
    REINA C VILLAREAL; Fiscal Year: 2013
    ..abstract_text> ..
  16. Robust BCT for Clinical Use
    DAVID KOPPERDAHL; Fiscal Year: 2010
    ..N. Diagnostics'business, and result in an important advance in the preventative care and treatment of osteoporosis. ..
  17. Effect of botulinum toxin plus vibration on bone in children with cerebral palsy
    Christopher M Modlesky; Fiscal Year: 2012
    ....
  18. Metabolic Effects of Antipsychotics in Children
    John W Newcomer; Fiscal Year: 2010
    ..Relevant data are critically needed to assess the risks of antipsychotic therapy in children, to identify targets for additional basic research, and to guide clinical decision-making. ..
  19. Body Composition and Energy Utilization in Spinal Muscular Atrophy
    Douglas Michael Sproule; Fiscal Year: 2012
    ..We will also study muscle imaging and electrical impedance as potential biomarkers of disease progression;the development of such biomarkers is of critical importance in the acceleration of clinical trials in SMA. ..
  20. Bone Marrow Adiposity, Bone and Body Composition
    Ann V Schwartz; Fiscal Year: 2012
    ..A better understanding of the process underlying the accumulation of marrow fat with age and osteoporosis may provide new targets for treatments to prevent bone loss. ..
  21. High Resolution Peripheral Quantitative CT
    MARY BETH LEONARD; Fiscal Year: 2013
    ..We have a detailed and ready-to-execute plan for operation that includes technical expertise and support, and full institutional commitment. ..
  22. Renal Osteodystrophy: A Fresh Approach
    Hartmut H Malluche; Fiscal Year: 2012
    ....
  23. Global HIV Drug Therapies and Mitochondrial Complications and Mechanisms
    Mariana Gerschenson; Fiscal Year: 2012
    ..Additionally, PBMCs intracellular concentrations of ZDV, d4T, 3TC, FTC, and TDF triphosphates will be assessed for exposure-response relationships with mitochondrial toxicity. ..
  24. Genetics of Bone Structure and Metabolism
    Michael C Mahaney; Fiscal Year: 2013
    ..risk - in humans in general, as well as those with effects more specific to peoples from an understudied region of the world. ..
  25. Bone Microarchitecture: The Framingham Osteoporosis Study
    Douglas P Kiel; Fiscal Year: 2013
    ....
  26. Examining the Effects of High Protein Diet on Outcomes in Heart Failure Patients
    Lorraine S Evangelista; Fiscal Year: 2013
    ..This information will provide evidence for rational recommendations for weight loss modalities that can be integrated in HF management and treatment guidelines. ..
  27. Influence of physical activity and weight loss on brain plasticity
    Kirk I Erickson; Fiscal Year: 2013
    ....
  28. Effects of Recombinant IGF-I in HIV Associated Metabolic Disease
    Roy J Kim; Fiscal Year: 2011
    ..The study may also increase our understanding of the role of the IGF-I hormone in regulating the amount and biological properties of human fat tissue. This could help us understand other medical conditions such as diabetes and obesity. ..
  29. Imaging evidence: Is there competition between marrow fat and bone?
    Wei Shen; Fiscal Year: 2010
    ....
  30. Obesity and bone development in young girls
    Scott B Going; Fiscal Year: 2013
    ..We expect to clarify the currently controversial relationships and provide critical information needed to develop efficacious interventions for optimal bone development. ..
  31. Fluoride &Other Factors in Childhood and Adolescent Bone Development
    Steven M Levy; Fiscal Year: 2013
    ..abstract_text> ..
  32. HIV, HCV, and gender effects on Liver, Bone, and Vascular Health
    Phyllis C Tien; Fiscal Year: 2013
    ....
  33. Body Composition &REE Responses to Bariatric Surgeries
    Dympna Gallagher; Fiscal Year: 2013
    ..Subjects will be a women and men (n=100) equally distributed between the New York and Pittsburgh sites. ..
  34. Prenatal Conditions and the Pathway to Obesity and Diabetes in Children
    Steven D Chernausek; Fiscal Year: 2013
    ..Defining the mechanisms, risk factors, and surrogate markers of future DM can lead new ways to prevent DM in high risk populations. ..
  35. Natural history of bone disease and the impact of growth hormone treatment in MPS
    LYNDA ELIZABETH POLGREEN; Fiscal Year: 2013
    ..Polgreen's research and career development into an independent investigator of pediatric metabolic bone disease. ..
  36. Combining Imaging and Modeling in Osteoporosis Fracture Risk Assessment
    GARY BEAUPRE; Fiscal Year: 2009
    ..Based on all of the above, we believe that the VA can and should play a central role in osteoporosis research, especially given the potential for a large number of aging male veterans to experience an osteoporosis-related fracture. ..
  37. BIOMEDICAL ANALYSIS OF HUMAN BIOSPECIMENS FOR DIPHR
    ERIN ALLEN; Fiscal Year: 2013
    ..Serum samples from the trial have been stored in the NICHD Bio-repository at -70[unreadable]C. Aliquots of the participants will be shipped to the laboratory ..
  38. An MRI-Based Method for Measuring Bone Mineral and Matrix Densities in Humans
    Alan C Seifert; Fiscal Year: 2013
    ....
  39. Predicting Hip Fracture Using a Biomechanical Approach
    Marian T Hannan; Fiscal Year: 2013
    ..This study has potential to significantly alter the way hip fractue risk is currently being assessed, and thus how patients are selected for drug therapy. ..
  40. Ultra-high Resolution pQCT as a Biomarker of Bone Strength in Osteoporosis Trials
    ELIZABETH J SHANE; Fiscal Year: 2010
    ..As fractures are associated with considerable morbidity and excess mortality, this research has high relevance to public health. ..
  41. FSH as a biomarker of bone strength in younger postmenopausal women
    Margaret L Gourlay; Fiscal Year: 2010
    ..This study will examine the potential for serum FSH to be used clinically as a biomarker of low bone strength in younger postmenopausal women. ..
  42. Optimizing Protein Intake in Older Americans with Mobility Limitations
    Shalendar Bhasin; Fiscal Year: 2013
    ..This issue has enormous public health and policy implications for older Americans. ..
  43. Exercise for Bone Health: Young Breast Cancer Survivors
    Joan Bloom; Fiscal Year: 2009
    ..Program dissemination will be facilitated by the stable nationwide infrastructure of community-based Y facilities. ..
  44. Bone Quality and Mechanical Competence In Chronic Kidney Disease
    Thomas L Nickolas; Fiscal Year: 2012
    ..PUBLIC HEALTH RELEVANCE: This study is highly relevant to public health, as fracture risk and its associated morbidity and mortality are exceedingly high in CKD patients and CKD and osteoporosis are highly coprevalent. ..
  45. Magnetic Resonance Imaging of Bound and Free Water in Cortical Bone
    Jiang Du; Fiscal Year: 2013
    ..The comprehensive characterization of bone in these conditions could have a profound impact in their diagnosis and treatment. ..
  46. Clinical Bone Mechanics Using HR-pQCT and MRI
    Felix W Wehrli; Fiscal Year: 2013
    ..This research will test the feasibility and establish the standard of high-resolution skeletal imaging in assessing bone health beyond the areal bone mineral density measurements obtained by dual-energy x-ray absorptiometry (DXA). ..
  47. A Patient Activation Intervention to Enhance Bone Health
    Fredric D Wolinsky; Fiscal Year: 2013
    ....
  48. BONE PROPERTIES IN HYPOPARATHYROIDISM: EFFECTS OF PTH
    John P Bilezikian; Fiscal Year: 2013
    ..Rather, we anticipate our results will have far broader implications, including greater understanding both of the normal control of the skeleton by PTH and of the anabolic activity of PTH in the treatment of postmenopausal osteoporosis. ..
  49. Modeling fracture prediction in spinal cord injury and disease
    Laura D Carbone; Fiscal Year: 2013
    ....
  50. Intensive Nutrition in ARDS: A Clinical Trial (INTACT)
    Carol L Braunschweig; Fiscal Year: 2012
    ..abstract_text> ..
  51. Bone Fracture Risk Assessment Through Bound - and Pore - Water MRI
    Mark D Does; Fiscal Year: 2013
    ..The proposed research aims to develop and evaluate MRI methods that can beDer predict bone fracture risk and provide more specific feedback on bone composition changes in response to therapy. ..
  52. Whole Body Vibration Training for Healthy Body Composition in Young Adults
    Kerri M Winters-Stone; Fiscal Year: 2013
    ....
  53. Optimization of vitamin D status and its effects on bone health of youth with IBD
    Helen M Pappa; Fiscal Year: 2012
    ..The impact of the results of this research on other pediatric populations with diseases that affect their bone health could be great. ..
  54. Novel Therapies for Metabolic Complications in Patients with Lipodystrophies
    Abhimanyu Garg; Fiscal Year: 2010
    ..Additionally, the findings may be applicable to treating metabolic complications in patients with obesity and type 2 diabetes. ..
  55. Determination of Skeletal Muscle Mass by Creatine Dilution
    Peggy Mannen Cawthon; Fiscal Year: 2013
    ..This simple test could be used clinically as an alternative to DXA to identify men at risk of physical decline and to refine sarcopenia definitions. ..
  56. Spinal abnormalities in neurofibomatosis type 1
    David H Viskochil; Fiscal Year: 2010
    ..This proposal will identify variables in patients with NF1 as prognostic factors for dystrophic scoliosis to improve clinical management. ..
  57. Skeletal health in obesity and after bariatric surgery
    ELAINE WEI YIN YU; Fiscal Year: 2013
    ....
  58. Sustained Skeletal Benefits of Adolescent Exercise
    Tamara A Scerpella; Fiscal Year: 2012
    ....
  59. A New Hip Fracture Risk Prediction Tool Based on Common Predictors and Hip Geomer
    Samy Missoum; Fiscal Year: 2012
    ..The study results will have an extremely significant public health impact by providing an innovative tool for hip fracture risk assessments. ..
  60. Periarticular Bone Density as a Biomarker for Early Knee OA
    Timothy E McAlindon; Fiscal Year: 2013
    ..If we are able to show that tibial paBMD is a good biomarker for knee OA, this will take us an important step closer towards finding an effective disease-modifying treatment for knee OA. ..
  61. Aging and Fracture Risk among HIV-infected and HIV-uninfected Men
    Todd T Brown; Fiscal Year: 2013
    ..Using a well-characterized cohort with an internal HIV-uninfected reference population, the proposed studies will improve our understanding of fracture risk in HIV infection, leading to effective strategies for fracture prevention. ..
  62. Epidemiologic Study of Bone Marrow Fat and Osteoporosis
    Jane Cauley; Fiscal Year: 2010
    ..It also opens a new opportunity for prevention and/or treatment of osteoporosis and osteoporotic fractures among at-risk populations. ..
  63. Calcium Absorption and Bone Formation During Puberty
    Steven Abrams; Fiscal Year: 2005
    ....
  64. FEMORAL OSTEOPOROSIS IN ELDERLY WOMEN
    Susan Greenspan; Fiscal Year: 1999
    ..Data derived from this study should provide the basic for an effective intervention to stabilize or increase femoral bone mass and reserve architectural integrity in elderly women. ..
  65. CHILD MOBILITY: ROLE OF STRENGTH, BODY FAT & ENERGY COST
    CRAIG MC DONALD; Fiscal Year: 2000
    ....
  66. EXERCISE AND ENERGY/SUBSTRATE UTIL IN BLACKS WITH NIDDM
    Dara Schuster; Fiscal Year: 2002
    ..This project is a continuum of previous research in which I have been involved while it examines and area of glucose metabolism in which little is known, the racial differences in the effects of exercise on glucose metabolism. ..
  67. ABDOMINAL FAT AND AUTONOMIC CIRCULATORY CONTROL IN HUMAN
    Kevin Davy; Fiscal Year: 2003
    ..abstract_text> ..
  68. MULTISCAN PHOTON ABSORPTIOMETRY & OSTEOPOROTIC FRACTURE
    Wilson Hayes; Fiscal Year: 1991
    ....
  69. Biomechanical Investigation of Pediatric Accidents
    Gina Bertocci; Fiscal Year: 2003
    ..The long term goal is to develop a clinical tool that predicts the likelihood of pediatric fracture for a given accident scenario aiding clinicians in determining between intentional and unintentional injury. ..
  70. OBESITY, GLUCOSE METABOLISM AND DIET IN OLDER WOMEN
    ALICE RYAN; Fiscal Year: 2001
    ..The proposed work will provide the candidate with the requisite skills and training to embark on an independent research career. ..
  71. 1H MRS to diagnose bone weakening from aging /inactivity
    Dieter Schellinger; Fiscal Year: 2001
    ..Each subset of data (totals 3 subsets) will be tabulated and be analyzed against the corresponding age normal rats (group A) using two-tailed Student t-test method. P < 0.05 is considered significant. ..
  72. Weight Loss and Exercise in Frail Obese Elderly Subjects
    DENNIS VILLAREAL; Fiscal Year: 2009
    ..The data generated from this proposed randomized controlled trial will ultimately establish appropriate treatment guidelines for the increasing number of frail obese elderly men and women. ..
  73. Biomechanics of Spine Fracture
    TONY KEAVENY; Fiscal Year: 2007
    ..abstract_text> ..