echo planar imaging

Summary

Summary: A type of MAGNETIC RESONANCE IMAGING that uses only one nuclear spin excitation per image and therefore can obtain images in a fraction of a second rather than the minutes required in traditional MRI techniques. It is used in a variety of medical and scientific applications.

Top Publications

  1. ncbi Image distortion correction in fMRI: A quantitative evaluation
    Chloe Hutton
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London WCIN 3BG, United Kingdom
    Neuroimage 16:217-40. 2002
  2. ncbi Modeling geometric deformations in EPI time series
    J L Andersson
    The Wellcome Department of Cognitive Neurology, London, United Kingdom
    Neuroimage 13:903-19. 2001
  3. ncbi Head and neck lesions: characterization with diffusion-weighted echo-planar MR imaging
    J Wang
    Department of Radiology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan
    Radiology 220:621-30. 2001
  4. pmc Efficient correction of inhomogeneous static magnetic field-induced distortion in Echo Planar Imaging
    Dominic Holland
    Multimodal Imaging Laboratory, The University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92037, USA
    Neuroimage 50:175-83. 2010
  5. ncbi Functional anatomy of impaired selective attention and compensatory processing in autism
    Matthew K Belmonte
    Cognitive Neuroimaging Laboratory, McLean Hospital, Belmont, MA 02478 1048, USA
    Brain Res Cogn Brain Res 17:651-64. 2003
  6. ncbi Characterization of focal liver lesions by ADC measurements using a respiratory triggered diffusion-weighted single-shot echo-planar MR imaging technique
    Melanie Bruegel
    Department of Radiology, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Str 22, 81675 Munich, Germany
    Eur Radiol 18:477-85. 2008
  7. ncbi Lymphomas and high-grade astrocytomas: comparison of water diffusibility and histologic characteristics
    Alexander C Guo
    Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710, USA
    Radiology 224:177-83. 2002
  8. ncbi Single-shot compensation of image distortions and BOLD contrast optimization using multi-echo EPI for real-time fMRI
    Nikolaus Weiskopf
    Institute of Medical Psychology and Behavioral Neurobiology, University of Tubingen, Tubingen, Germany
    Neuroimage 24:1068-79. 2005
  9. ncbi Optimized EPI for fMRI studies of the orbitofrontal cortex
    R Deichmann
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, London WC1N 3BG, UK
    Neuroimage 19:430-41. 2003
  10. ncbi Echo planar imaging at 4 Tesla with minimum acoustic noise
    Dardo G Tomasi
    Medical Department, Brookhaven National Laboratory, Upton, New York 11973, USA
    J Magn Reson Imaging 18:128-30. 2003

Detail Information

Publications240 found, 100 shown here

  1. ncbi Image distortion correction in fMRI: A quantitative evaluation
    Chloe Hutton
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London WCIN 3BG, United Kingdom
    Neuroimage 16:217-40. 2002
    ..However, we suggest that the variance between successively measured field maps introduces additional unwanted variance in the voxel time-series and is therefore not adequate to correct for time-varying distortions...
  2. ncbi Modeling geometric deformations in EPI time series
    J L Andersson
    The Wellcome Department of Cognitive Neurology, London, United Kingdom
    Neuroimage 13:903-19. 2001
    ..An experiment on a subject performing voluntary movements in the scanner yielded plausible estimates of the deformation fields and their application to "unwarp" the time series significantly reduced movement-related variance...
  3. ncbi Head and neck lesions: characterization with diffusion-weighted echo-planar MR imaging
    J Wang
    Department of Radiology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan
    Radiology 220:621-30. 2001
    ..22 x 10(-3) mm(2)/sec was used for predicting malignancy, the highest accuracy of 86%, with 84% sensitivity and 91% specificity, was obtained. CONCLUSION: Measurement of ADCs may be used to characterize head and neck lesions...
  4. pmc Efficient correction of inhomogeneous static magnetic field-induced distortion in Echo Planar Imaging
    Dominic Holland
    Multimodal Imaging Laboratory, The University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92037, USA
    Neuroimage 50:175-83. 2010
    Single-shot Echo Planar Imaging (EPI) is one of the most efficient magnetic resonance imaging (MRI) acquisition schemes, producing relatively high-definition images in 100 ms or less...
  5. ncbi Functional anatomy of impaired selective attention and compensatory processing in autism
    Matthew K Belmonte
    Cognitive Neuroimaging Laboratory, McLean Hospital, Belmont, MA 02478 1048, USA
    Brain Res Cogn Brain Res 17:651-64. 2003
    ..These low-level attentional traits may be the developmental basis for higher-order cognitive styles such as weak central coherence...
  6. ncbi Characterization of focal liver lesions by ADC measurements using a respiratory triggered diffusion-weighted single-shot echo-planar MR imaging technique
    Melanie Bruegel
    Department of Radiology, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Str 22, 81675 Munich, Germany
    Eur Radiol 18:477-85. 2008
    ..63 x 10(-3)mm2/s. Measurements of the ADCs of focal liver lesions on the basis of a respiratory triggered DW-SS-EPI sequence may constitute a useful supplementary method for lesion characterization...
  7. ncbi Lymphomas and high-grade astrocytomas: comparison of water diffusibility and histologic characteristics
    Alexander C Guo
    Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710, USA
    Radiology 224:177-83. 2002
    ..To determine if water diffusivity within lymphomas and high-grade astrocytomas correlates with cellularity...
  8. ncbi Single-shot compensation of image distortions and BOLD contrast optimization using multi-echo EPI for real-time fMRI
    Nikolaus Weiskopf
    Institute of Medical Psychology and Behavioral Neurobiology, University of Tubingen, Tubingen, Germany
    Neuroimage 24:1068-79. 2005
    ..Significant reduction in geometric distortion is shown both for phantom images and human fMRI data. Moreover, sensitivity to the blood oxygen level-dependent (BOLD) effect is increased by weighted summation of the undistorted images...
  9. ncbi Optimized EPI for fMRI studies of the orbitofrontal cortex
    R Deichmann
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, London WC1N 3BG, UK
    Neuroimage 19:430-41. 2003
    A common problem in gradient-echo echo planar imaging (EPI) is the occurrence of image distortions and signal losses caused by susceptibility gradients near air/tissue interfaces...
  10. ncbi Echo planar imaging at 4 Tesla with minimum acoustic noise
    Dardo G Tomasi
    Medical Department, Brookhaven National Laboratory, Upton, New York 11973, USA
    J Magn Reson Imaging 18:128-30. 2003
    To minimize the acoustic sound pressure levels of single-shot echo planar imaging (EPI) acquisitions on high magnetic field MRI scanners.
  11. ncbi Rapid T(1) mapping using multislice echo planar imaging
    S Clare
    Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, University of Oxford, Oxford, UK
    Magn Reson Med 45:630-4. 2001
    ..In this study, clinically acceptable images are obtained by using single-shot echo planar imaging (EPI) with an acquisition scheme that maximizes signal-to-noise while minimizing the scan time...
  12. ncbi Validation of fast MR thermometry at 1.5 T with gradient-echo echo planar imaging sequences: phantom and clinical feasibility studies
    Alexandru Cernicanu
    Department of Radiology, Geneva University Hospital, Switzerland
    NMR Biomed 21:849-58. 2008
    ..5 T with segmented gradient-echo echo planar imaging (GRE-EPI) sequences during liver tumour radiofrequency (RF) ablation...
  13. ncbi Short-scan-time multi-slice diffusion MRI of the mouse cervical spinal cord using echo planar imaging
    Virginie Callot
    Centre de Résonance Magnétique Biologique et Médicale CRMBM, UMR CNRS No 6612, Faculte de Medecine de Marseille, Universite de la Mediterranee, Marseille, France
    NMR Biomed 21:868-77. 2008
    ..The purpose of this work was to investigate whether the use of echo planar imaging (EPI) would provide good-quality diffusion MR images of mouse SC, as well as accurate measurements of ..
  14. ncbi Compensation of susceptibility-induced BOLD sensitivity losses in echo-planar fMRI imaging
    R Deichmann
    Institute of Neurology, Wellcome Department of Cognitive Neurology, London WC1N 3BG, United Kingdom
    Neuroimage 15:120-35. 2002
    ..The results suggest that the compensation method allows for the detection of activation in brain areas which are usually unavailable for BOLD studies...
  15. ncbi "Silent" MRI with soft gradient pulses
    F Hennel
    FORENAP, MR Center, Rouffach, France
    Magn Reson Med 42:6-10. 1999
    ..High-quality images could be acquired at noise levels as low as 40 dBA (GE and SE) and 60 dBA (RARE)...
  16. ncbi Functional MRI using sensitivity-encoded echo planar imaging (SENSE-EPI)
    Christine Preibisch
    Department of Neuroradiology, University Frankfurt, Frankfurt, Germany
    Neuroimage 19:412-21. 2003
    ..Thus, SENSE-EPI allows to substantially increase speed and spatial resolution in fMRI. At SENSE reduction factors up to R = 2, the potential drawbacks regarding signal-to-noise and statistical power are almost negligible...
  17. ncbi In vivo diffusion measurements as an indication of fetal lung maturation using echo planar imaging at 0.5T
    R J Moore
    Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham NG7 2RD, UK
    Magn Reson Med 45:247-53. 2001
    ..This model predicted the in vivo data reasonably well, and indicated that MR measurements of fetal lung diffusion are a marker for the degree of vascularization of the terminal tubules. Magn Reson Med 45:247-253, 2001...
  18. ncbi Quantifying the spatial resolution of the gradient echo and spin echo BOLD response at 3 Tesla
    Laura M Parkes
    F C Donders Centre for Cognitive Neuroimaging, University of Nijmegen, The Netherlands
    Magn Reson Med 54:1465-72. 2005
    ..The spin echo response shows a 13% reduction in the width of the PSF, but at a cost of at least 3-fold reduction in contrast to noise ratio...
  19. ncbi MRI receiver frequency response as a contributor to Nyquist ghosting in echo planar imaging
    Ioannis Delakis
    Department of Bioengineering, Imperial College London, Exhibition Road, South Kensington, London SW7 2AZ, United Kingdom
    J Magn Reson Imaging 22:324-8. 2005
    ..To study the frequency response characteristic of the MRI signal receiver system as a contributing factor to the formation of Nyquist ghosting in echo-planar imaging (EPI)...
  20. ncbi Diffusion-weighted magnetic resonance imaging for monitoring diffusion changes in rectal carcinoma during combined, preoperative chemoradiation: preliminary results of a prospective study
    Patrick A Hein
    Department of Radiotherapy and Radiooncology, University of Innsbruck, Innsbruck, Austria
    Eur J Radiol 45:214-22. 2003
    ..To evaluate the clinical value of diffusion-weighted magnetic resonance imaging (DW-MRI) to monitor response of primary carcinoma of the rectum to preoperative chemoradiation by measuring tumor apparent diffusion coefficient (ADC)...
  21. ncbi Detection of head and neck squamous cell carcinoma with diffusion weighted MRI after (chemo)radiotherapy: correlation between radiologic and histopathologic findings
    Vincent Vandecaveye
    Department of Radiology, University Hospitals Leuven, Leuven, Belgium
    Int J Radiat Oncol Biol Phys 67:960-71. 2007
    ..To investigate the value of diffusion weighted magnetic resonance imaging (DW-MRI) in differentiating persistent or recurrent head and neck squamous cell carcinoma (HNSCC) from nontumoral postradiotherapeutic alterations...
  22. ncbi Evaluation of true diffusion, perfusion factor, and apparent diffusion coefficient in non-necrotic liver metastases and uncomplicated liver hemangiomas using black-blood echo planar imaging
    Kenneth Coenegrachts
    Department of Radiology, AZ St Jan AV, Ruddershove 10, B 8000 Bruges, Belgium
    Eur J Radiol 69:131-8. 2009
    ..apparent diffusion coefficient at low b-values (ADC(low)) for differentiation between liver metastases and hemangiomas based on respiratory-triggered high-resolution Black-Blood Single-Shot SpinEcho Echo Planar Imaging (BB SS SE-EPI).
  23. ncbi Diffusion-weighted imaging (DWI) in MR mammography (MRM): clinical comparison of echo planar imaging (EPI) and half-Fourier single-shot turbo spin echo (HASTE) diffusion techniques
    P A T Baltzer
    Institute of Diagnostic and Interventional Radiology, Friedrich Schiller University Jena, Erlanger Allee 101, 07740, Jena, Germany
    Eur Radiol 19:1612-20. 2009
    ..This study investigated the use of echo planar imaging (EPI) and half-Fourier acquired single-shot turbo spin echo (HASTE)-DWI with respect to the three ..
  24. ncbi Zoomed functional imaging in the human brain at 7 Tesla with simultaneous high spatial and high temporal resolution
    Josef Pfeuffer
    Center for Magnetic Resonance Research, University of Minnesota Medical School, 2021 6th Street S E, Minneapolis, Minnesota 55455, USA
    Neuroimage 17:272-86. 2002
    ..The magnetization transfer effect induced by the outer-volume suppression pulses was investigated and found to be increased during neuronal activity...
  25. ncbi Role of diffusion-weighted echo-planar MR imaging in differentiation of residual or recurrent head and neck tumors and posttreatment changes
    A A K Abdel Razek
    Department of Diagnostic Radiology, Faculty of Medicine, Mansoura University, Mansoura, Egypt
    AJNR Am J Neuroradiol 28:1146-52. 2007
    ..The purpose of this work was to evaluate whether diffusion-weighted MR imaging can be used in differentiating residual or recurrent head and neck tumors from postoperative or postradiation changes...
  26. ncbi Myocardial first pass perfusion: steady-state free precession versus spoiled gradient echo and segmented echo planar imaging
    Yi Wang
    Research and Education Department, St Francis Hospital, Roslyn, New York 11576, USA
    Magn Reson Med 54:1123-9. 2005
    ..Mean RMU was similar between SSFP and spoiled GRE, but there was a 58% increase in RMU with SSFP versus segmented EPI...
  27. ncbi Diffusion-weighted imaging of cerebral infarctions: are higher B values better?
    Jonathan H Burdette
    Department of Radiology, Wake Forest Unversity School of Medicine, Winston Salem, North Carolina 27157, USA
    J Comput Assist Tomogr 26:622-7. 2002
    ..The purpose of this work is to determine whether high -value ( = 3,000 s/mm ) diffusion-weighted (DW) imaging is superior to low -value ( = 1,000 s/mm ) DW imaging for the detection of cerebral infarctions older than 6 h...
  28. ncbi Sensitivity-encoded (SENSE) echo planar fMRI at 3T in the medial temporal lobe
    Conny F Schmidt
    Institute for Biomedical Engineering, University of Zurich and ETH Zurich, Gloriastrasse 35, CH 8092 Zurich, Switzerland
    Neuroimage 25:625-41. 2005
    ..We present two fMRI studies comparing SENSE single-shot (ssh) echo planar imaging (EPI) at acceleration factors of 2.0, 2.4, 2.7, and 3.0 with conventional sshEPI at TE of 22 and 35 ms...
  29. ncbi An investigation of the value of spin-echo-based fMRI using a Stroop color-word matching task and EPI at 3 T
    David G Norris
    Max Planck Institute for Cognitive Neuroscience, Stephanstrasse 1a, D 04103 Leipzig, Germany
    Neuroimage 15:719-26. 2002
    ....
  30. ncbi Effect of spatial smoothing on physiological noise in high-resolution fMRI
    Christina Triantafyllou
    MGH MIT HMS A A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Dept of Radiology, Mailcode 2301, Bldg 149, 13th Street, Charlestown, MA 02129, USA
    Neuroimage 32:551-7. 2006
    ....
  31. ncbi An evaluation of the use of magnetic field maps to undistort echo-planar images
    Rhodri Cusack
    MRC Cognition and Brain Sciences Unit, Cambridge, United Kingdom
    Neuroimage 18:127-42. 2003
    ..Overall, undistorting EPIs using field maps has proved extremely successful, improving the anatomical localization of activation and increasing statistical power...
  32. ncbi Interleaved silent steady state (ISSS) imaging: a new sparse imaging method applied to auditory fMRI
    Christian Schwarzbauer
    MRC Cognition and Brain Sciences Unit, Cambridge, UK
    Neuroimage 29:774-82. 2006
    The acoustic scanner noise that is generated by rapid gradient switching in echo planar imaging (EPI) is an important confounding factor in auditory fMRI...
  33. ncbi Enhancing BOLD response in the auditory system by neurophysiologically tuned fMRI sequence
    Erich Seifritz
    University Hospital of Clinical Psychiatry, University of Bern, 3000 Bern, Switzerland
    Neuroimage 29:1013-22. 2006
    ..Finally, tonotopic mapping using continuous-sound fMRI demonstrates that enhanced functional signal-to-noise in BOLD response translates into improved spatial separability of specific sound representations...
  34. ncbi Point spread function mapping with parallel imaging techniques and high acceleration factors: fast, robust, and flexible method for echo-planar imaging distortion correction
    M Zaitsev
    Department of Radiologic Research, Medical Physics, University Hospital of Freiburg, Germany
    Magn Reson Med 52:1156-66. 2004
    ..The reliable performance of the PSF mapping technique is demonstrated on phantom and volunteer scans at field strengths of up to 4 T...
  35. ncbi Common SENSE (sensitivity encoding using hardware common to all MR scanners): a new method for single-shot segmented echo planar imaging
    David W Carmichael
    University College London, Department of Medical Physics and Bioengineering, London, United Kingdom
    Magn Reson Med 54:402-10. 2005
    ..The most promising application for this technique is in improving the performance of echo planar imaging (EPI) at high field...
  36. ncbi Positive or negative blips? The effect of phase encoding scheme on susceptibility-induced signal losses in EPI
    Claudia De Panfilis
    Wolfson Brain Imaging Centre, University of Cambridge, Addenbrooke s Hospital, BOX 65 Cambridge, CB2 2QQ, UK
    Neuroimage 25:112-21. 2005
    ..Our results suggest that this optimization method would be useful in future fMRI studies to improve the sensitivity in regions compromised by susceptibility effects...
  37. ncbi Echo time dependence of BOLD contrast and susceptibility artifacts
    Maria Luisa Gorno-Tempini
    Wellcome Department of Cognitive Neurology, Institute of Neurology, 12 Queen Square, London WC1N 3BG, United Kingdom
    Neuroimage 15:136-42. 2002
    ..However, although the amount of signal loss is reduced at the lower TE, this does not appear to be sufficient to recover the BOLD signal in regions affected by susceptibility artifacts (i.e., anterior temporal lobes)...
  38. ncbi Correlation of the apparent diffusion coefficient and the creatine level in early ischemic stroke: a comparison of different patterns by magnetic resonance
    H Rumpel
    Department of Diagnostic Radiology, Singapore General Hospital, Singapore
    J Magn Reson Imaging 13:335-43. 2001
    ..Greatly lowered ADC values occur within the context of a stable cellularity. ADC and the Cre level have complementary roles in the characterization of stroke lesion with regard to the sequential stage...
  39. ncbi Compensation of susceptibility-induced signal loss in echo-planar imaging for functional applications
    D Cordes
    Department of Medical Physics, The University of Wisconsin, 600 Highland Avenue, Madison, WI 53792, USA
    Magn Reson Imaging 18:1055-68. 2000
    ..The effectiveness of this method is demonstrated by recovering signal voids in the orbitofrontal cortex, parahippocampal/amygdala region, and inferior visual association cortex near the cerebellum...
  40. pmc Event-related functional magnetic resonance imaging: modelling, inference and optimization
    O Josephs
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London, UK
    Philos Trans R Soc Lond B Biol Sci 354:1215-28. 1999
    ..Finally, we illustrate various event-related models with examples from recent studies...
  41. ncbi Diffusion-weighted single shot echo planar imaging of colorectal cancer using a sensitivity-encoding technique
    Katsuhiro Nasu
    National Cancer Center Hospital East, Department of Radiology, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
    Jpn J Clin Oncol 34:620-6. 2004
    We wanted to determine the feasibility of diffusion-weighted single shot echo planar imaging using a sensitivity-encoding technique (SENSE-DWI) in depicting colorectal cancer.
  42. ncbi Improved diffusion-weighted single-shot echo-planar imaging (EPI) in stroke using sensitivity encoding (SENSE)
    R Bammer
    Magnetic Resonance Institute, Karl Franzens University, Graz, Austria
    Magn Reson Med 46:548-54. 2001
    ..Because of the faster k-space traversal, this novel technique is able to reduce typical EPI artifacts and increase spatial resolution while simultaneously remaining insensitive to bulk motion...
  43. ncbi Diffusion-weighted imaging of human carotid artery using 2D single-shot interleaved multislice inner volume diffusion-weighted echo planar imaging (2D ss-IMIV-DWEPI) at 3T: diffusion measurement in atherosclerotic plaque
    Seong Eun Kim
    Department of Radiology, Utah Center for Advanced Imaging Research, Salt Lake City, Utah 84108, USA
    J Magn Reson Imaging 30:1068-77. 2009
    To determine if 2D single-shot interleaved multislice inner volume diffusion-weighted echo planar imaging (ss-IMIV-DWEPI) can be used to obtain quantitative diffusion measurements that can assist in the identification of plaque ..
  44. ncbi Functional MRI of the human amygdala?
    K D Merboldt
    Biomedizinische NMR Forschungs GmbH am Max Planck Institut für biophysikalische Chemie, Gottingen, 37070, Germany
    Neuroimage 14:253-7. 2001
    ..Although high-resolution BOLD MRI is at the expense of temporal resolution and volume coverage, it seems to provide the only solution to this physical problem...
  45. ncbi Respiration-induced B0 fluctuations and their spatial distribution in the human brain at 7 Tesla
    Pierre Francois van de Moortele
    Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota Medical School, Minneapolis 55455, USA
    Magn Reson Med 47:888-95. 2002
    ..Consequential apparent motions in the EPI series, as well as the implications of slice orientation for correction strategies are discussed...
  46. ncbi Reduction of magnetic field inhomogeneity artifacts in echo planar imaging with SENSE and GESEPI at high field
    Qing X Yang
    Department of Radiology, Center for NMR Research, Pennsylvania State University College of Medicine, Milton S Hershey Medical Center, Hershey 17033, USA
    Magn Reson Med 52:1418-23. 2004
    Geometric distortion, signal-loss, and image-blurring artifacts in echo planar imaging (EPI) are caused by frequency shifts and T(2)(*) relaxation distortion of the MR signal along the k-space trajectory due to magnetic field ..
  47. ncbi Composite image formation in z-shimmed functional MR imaging
    R T Constable
    Dept of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT 06520 8042, USA
    Magn Reson Med 42:110-7. 1999
    ..Time efficiency is shown to be dependent on field uniformity. Theory, computer simulations, and results from fMRI studies are used to demonstrate the performance of these methods...
  48. ncbi On the synchronization of transcranial magnetic stimulation and functional echo-planar imaging
    Sven Bestmann
    Biomedizinische NMR Forschungs GmbH, Max Planck Institut fur biophysikalische Chemie, Gottingen, Germany
    J Magn Reson Imaging 17:309-16. 2003
    ..To minimize artifacts in echo-planar imaging (EPI) of human brain function introduced by simultaneous transcranial magnetic stimulation (TMS)...
  49. ncbi Functional MRI of the rodent somatosensory pathway using multislice echo planar imaging
    Shella D Keilholz
    Laboratory of Functional and Molecular Imaging, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    Magn Reson Med 52:89-99. 2004
    ..Optimal activation occurred in all areas at 3 Hz. These results demonstrate that whole-brain fMRI can be performed on rodents at 11.7 T to probe a well-defined neural network...
  50. ncbi Malignant hepatic tumor detection with ferumoxides-enhanced MR imaging with a 1.5-T system: comparison of four imaging pulse sequences
    M Kanematsu
    Department of Radiology, Gifu University School of Medicine, Gifu 500 8705, Japan
    J Magn Reson Imaging 13:249-57. 2001
    ....
  51. ncbi Glial tumor grading and outcome prediction using dynamic spin-echo MR susceptibility mapping compared with conventional contrast-enhanced MR: confounding effect of elevated rCBV of oligodendrogliomas [corrected]
    Michael H Lev
    Departments of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    AJNR Am J Neuroradiol 25:214-21. 2004
    ..We compared the specificity of SE rCBV mapping with that of conventional, contrast material-enhanced MR imaging in differentiating high- from low-grade glial tumors and in predicting survival of patients with these lesions...
  52. ncbi Combination of BOLD-fMRI and VEP recordings for spin-echo MRI detection of primary magnetic effects caused by neuronal currents
    Marta Bianciardi
    Laboratory of Neuroimaging, Foundation Santa Lucia I R C C S, 00179, Rome, Italy
    Magn Reson Imaging 22:1429-40. 2004
    ..Finally, results from a pilot study using the proposed combination of VEP recordings and MRI techniques are reported, suggesting the feasibility of this method...
  53. ncbi Fast spectroscopic imaging strategies for potential applications in fMRI
    Robert V Mulkern
    Department of Radiology, Children s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Magn Reson Imaging 22:1395-405. 2004
    ..Fast spectroscopic methods directed towards the 31P signals from phosphocreatine (PCr) and adenosine tri-phosphates (ATP) are also technically feasible and may prove useful for studying cerebral energetics within fMRI contexts...
  54. ncbi Correction for direction-dependent distortions in diffusion tensor imaging using matched magnetic field maps
    Bin Chen
    Brain Imaging and Analysis Center, Box 3918, DUMC, Duke University, Durham, NC 27710, USA
    Neuroimage 30:121-9. 2006
    ....
  55. ncbi Effects of oxygen saturation on BOLD and arterial spin labelling perfusion fMRI signals studied in a motor activation task
    Pasi I Tuunanen
    Faculty of Life Sciences, The University of Manchester, Manchester, UK
    Neuroimage 30:102-9. 2006
    ..These observations indicate that haemodynamic and metabolic responses may be heterogeneous in brain during execution of motor functions in mild hypoxia...
  56. ncbi Initial attempts at directly detecting alpha wave activity in the brain using MRI
    Daniel Konn
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, NG7 2RD, UK
    Magn Reson Imaging 22:1413-27. 2004
    ..Using these criteria the data obtained were consistent with direct detection of alpha wave activity in three of the four volunteers. No significant MR signal fluctuations due to evoked activity were identified...
  57. ncbi Anatomical and functional MR imaging in the macaque monkey using a vertical large-bore 7 Tesla setup
    Josef Pfeuffer
    Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, 72012 Tübingen, Germany
    Magn Reson Imaging 22:1343-59. 2004
    ..The exquisite sensitivity of the system and the increased specificity of the hemodynamic signals promise further insights into the relationship of the latter to the underlying physiological activity...
  58. ncbi Single TrAjectory Radial (STAR) imaging
    Gordon E Sarty
    Department of Psychology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Magn Reson Med 51:445-51. 2004
    ..It is shown that such oversampling potentially reduces the image degrading effect of magnetic field inhomogeneities so that the motion robust features of radial imaging may be realized in a segmented EPI approach...
  59. ncbi Periodically rotated overlapping parallel lines with enhanced reconstruction-based diffusion tensor imaging. Comparison with echo planar imaging-based diffusion tensor imaging
    Osamu Abe
    Department of Radiology, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    J Comput Assist Tomogr 28:654-60. 2004
    To evaluate diffusion tensor imaging (DTI) based on periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) compared with DTI based on single-shot echo planar imaging (EPI).
  60. ncbi Variation of BOLD hemodynamic responses across subjects and brain regions and their effects on statistical analyses
    Daniel A Handwerker
    Henry H Wheeler Jr Brain Imaging Center, Helen Wills Neuroscience Institute and Department of Psychology, University of California, Berkeley, CA 94720, USA
    Neuroimage 21:1639-51. 2004
    ..These results highlight the benefits of determining the best possible HRF estimate and potential negative consequences of assuming HRF consistency across subjects or brain regions...
  61. ncbi Neonatal brain: regional variability of in vivo MR imaging relaxation rates at 3.0 T--initial experience
    Lori Anne Williams
    Imaging Division, Lawson Health Research Institute, London, Ontario, Canada
    Radiology 235:595-603. 2005
    ..0 T in neonatal brain, the relationship between these rates, and their potential use for gray matter (GM) versus white matter (WM) tissue discrimination...
  62. ncbi Importance of T2*-weighted gradient-echo MRI for diagnosis of cortical vein thrombosis
    Franz A Fellner
    Institut fur Radiologie, Landes Nervenklinik Wagner Jauregg, Linz, Austria
    Eur J Radiol 56:235-9. 2005
    ..administration of contrast medium, T2*-weighted conventional gradient-echo (GRE), T2*-weighted spin-echo echo planar imaging (SE EPI), both without and with diffusion weighting as well as two-dimensional (2D) venous time-of-flight (..
  63. ncbi Spiral imaging: a critical appraisal
    Kai Tobias Block
    Biomedizinische NMR Forschungs GmbH am Max Planck Institut für biophysikalische Chemie, Gottingen, Germany
    J Magn Reson Imaging 21:657-68. 2005
    ..Taken together, while spiral imaging may find its niche applications, most high-speed imaging needs are more easily served by EPI...
  64. ncbi Geometric distortion correction of high-resolution 3 T diffusion tensor brain images
    Siamak Ardekani
    Biomedical Engineering IDP, UCLA, Los Angeles, California 90095 1721, USA
    Magn Reson Med 54:1163-71. 2005
    ..In conclusion, the warping algorithm is effective in reducing geometric distortions, enabling generation of anatomically correct diffusion tensor images at 3 T...
  65. ncbi Spatial sensitivity and temporal response of spin echo and gradient echo bold contrast at 3 T using peak hemodynamic activation time
    Justin Hulvershorn
    Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuroimage 24:216-23. 2005
    ..Spatial overlay of SE and GE PHAT maps onto structural images reveal markedly different spatial profiles and further support the interpretation that shorter peak times correlate to improved spatial sensitivity...
  66. ncbi A method of generalized projections (MGP) ghost correction algorithm for interleaved EPI
    K J Lee
    Academic Unit of Radiology, University of Sheffield, Royal Hallamshire Hospital, Sheffield S10 2JF, UK
    IEEE Trans Med Imaging 23:839-48. 2004
    ..In simulations with phase variation between consecutive shots for n-interleaved echo planar imaging (EPI), ghost reduction was achieved for n = 2 only...
  67. pmc PROPELLER EPI: an MRI technique suitable for diffusion tensor imaging at high field strength with reduced geometric distortions
    Fu Nien Wang
    Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan, R O C
    Magn Reson Med 54:1232-40. 2005
    ..A higher signal-to-noise ratio (SNR) compared to single-shot EPI at an identical total scan time was achieved, which is advantageous for routine DTI applications in clinical practice...
  68. ncbi 3D DT-MRI using a reduced-FOV approach and saturation pulses
    Jiun Jie Wang
    School of Medical Technology, ChangGung University, Taoyuan County, Taiwan
    Magn Reson Med 51:853-7. 2004
    ..This method enables DT measurements to be obtained with high isotropic spatial resolution and whole-brain coverage. To avoid ghosting artifacts, the data are combined in image space rather than in k-space...
  69. ncbi Online motion correction for diffusion-weighted segmented-EPI and FLASH imaging
    K S Weih
    Max Planck Institute of Cognitive, NeuroscienceStephanstr 1a, D 04103, Leipzig, Germany
    MAGMA 16:277-83. 2004
    ..High quality images were obtained for both methods examined. Online motion correction brings direct benefits to both the diffusion-weighted segmented-EPI and FLASH techniques...
  70. ncbi Diffusion-weighted imaging of prostate cancer
    Ryota Shimofusa
    Department of Radiology, Chiba University Hospital, Chiba, Japan
    J Comput Assist Tomogr 29:149-53. 2005
    ..The purpose of this study was to assess whether T2-weighted (T2W) imaging with diffusion-weighted (DW) imaging could improve prostate cancer detection as compared with T2W imaging alone...
  71. ncbi Reference-scan-free method for automated correction of Nyquist ghost artifacts in echoplanar brain images
    Yan Zhang
    Laboratory for Structural NMR Imaging, Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Magn Reson Med 51:621-4. 2004
    ..In vivo data demonstrate the effectiveness of the algorithm showing ghost suppression comparable to that achievable with the reference-scan method...
  72. ncbi Estimation of general linear model coefficients for real-time application
    E Bagarinao
    Life Electronics Research Laboratory, National Institute of Advanced Industrial Science and Technology, Osaka, Japan
    Neuroimage 19:422-9. 2003
    ..Results of the analysis of an fMRI study using this approach showed the algorithm's potential for real-time application...
  73. ncbi Correction of physiologically induced global off-resonance effects in dynamic echo-planar and spiral functional imaging
    Josef Pfeuffer
    Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota Medical School, Minneapolis, Minnesota, USA
    Magn Reson Med 47:344-53. 2002
    ..The correction is simple to apply and can correct for other sources of frequency drift and fluctuations in dynamic imaging...
  74. ncbi Partial k-space reconstruction in single-shot diffusion-weighted echo-planar imaging
    Pippa Storey
    Radiology Department, Evanston Northwestern Healthcare, Evanston, Illinois 60201, USA
    Magn Reson Med 57:614-9. 2007
    ..The adaptive algorithm produces artifact-free images when the echo is shifted into the high positive k-space range, and reduces to the standard homodyne algorithm in the absence of bulk motion...
  75. ncbi Parallel magnetic resonance imaging
    David J Larkman
    The Imaging Sciences Department, Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK
    Phys Med Biol 52:R15-55. 2007
    ..Well-established applications including angiography, cardiac imaging and applications using echo planar imaging are reviewed and we discuss what makes a good application for parallel imaging...
  76. ncbi Phantom-based evaluation of geometric distortions in functional magnetic resonance and diffusion tensor imaging
    Seppo Mattila
    Brain Research Unit, Low Temperature Laboratory, TKK, Helsinki University of Technology, FI 02015 TKK, Espoo, Finland
    Magn Reson Med 57:754-63. 2007
    ..Possible future applications for this type of phantom include quality assurance and calibration of the hardware and software used in EPI-based functional MRI and DTI...
  77. ncbi The effect of varying echo spacing within a multiecho acquisition: better characterization of long T2 components
    Matthew G Skinner
    Department of Medical Physics, Toronto Sunnybrook Regional Cancer Center, Toronto, ON, Canada M4H 1L7
    Magn Reson Imaging 25:840-7. 2007
    ..On the basis of these results, we recommend the use of extended DeltaTE2 values for imaging patients with lesions, without the risk of losing valuable short T2 information...
  78. pmc Clinical multishot DW-EPI through parallel imaging with considerations of susceptibility, motion, and noise
    Stefan Skare
    Lucas MRS I Center, Department of Radiology, Stanford University, California 94305, USA
    Magn Reson Med 57:881-90. 2007
    ..The image quality improvements without SNR efficiency loss, together with motion tolerance, make the GRAPPA-driven DW-EPI sequence clinically attractive...
  79. ncbi Contrast-enhanced MR imaging of the brain using T1-weighted FLAIR with BLADE compared with a conventional spin-echo sequence
    Shinji Naganawa
    Department of Radiology, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Shouwa ku, Nagoya, 466 8550, Japan
    Eur Radiol 18:337-42. 2008
    ..6% respectively, while on axial T1W-FLAIR BLADE they were 100% and 100%. T1W-FLAIR BLADE seems to be capable of replacing T1W-SE, at least for axial post-contrast imaging to detect brain metastases...
  80. ncbi Quantitative MR evaluation of intracranial epidermoid tumors by fast fluid-attenuated inversion recovery imaging and echo-planar diffusion-weighted imaging
    S Chen
    Department of Neurosurgery, Hiroshima University School of Medicine, Hiroshima, Japan
    AJNR Am J Neuroradiol 22:1089-96. 2001
    ..Echo-planar DW imaging provides the best lesion conspicuity among the five MR methods. The hyperintensity of epidermoid tumors on echo-planar DW imaging is not caused by the diffusion restriction but by the T2 shine-through effect...
  81. ncbi White-marker imaging--separating magnetic susceptibility effects from partial volume effects
    Jan Henry Seppenwoolde
    Image Sciences Institute, University Medical Center Utrecht, Department of Radiology, The Netherlands
    Magn Reson Med 58:605-9. 2007
    ..The results show that PV effects were eliminated in the in vitro experiments and were virtually absent under in vivo conditions...
  82. ncbi T2 relaxation measurements in X-linked adrenoleukodystrophy performed using dual-echo fast fluid-attenuated inversion recovery MR imaging
    E R Melhem
    Department of Radiology and Radiological Sciences, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    AJNR Am J Neuroradiol 22:773-6. 2001
    ..On the basis of dual-echo fast fluid-attenuated inversion recovery images and T2 maps, the affected white matter could be divided into two distinct zones in four patients with cerebral X-linked adrenoleukodystrophy...
  83. ncbi Optimized distortion correction technique for echo planar imaging
    N K Chen
    Center for MR Research, ENH Research Institute, Northwestern University, Evanston, Illinois 60201, USA
    Magn Reson Med 45:525-8. 2001
    ..The effectiveness of this technique is illustrated with EPI studies on phantoms and animal subjects. Implementation to different versions of EPI sequences is also described. Magn Reson Med 45:525-528, 2001...
  84. ncbi Statistical framework and noise sensitivity of the amplitude radial correlation contrast method
    Zeev Gideon Kipervaser
    MRI MRS Laboratory, Human Biology Research Center, Department of Medical Biophysics, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Magn Reson Med 58:554-61. 2007
    ....
  85. ncbi Regularized, fast, and robust analytical Q-ball imaging
    Maxime Descoteaux
    Odyssee Project Team, INRIA ENPC ENS, INRIA Sophia Antipolis, France
    Magn Reson Med 58:497-510. 2007
    ..We show that our technique is also able to recover known fiber crossings in the human brain and provides the practical advantage of being up to 15 times faster than original numerical QBI method...
  86. ncbi High resolution single-shot EPI at 7T
    Oliver Speck
    Department of Biomedical Magnetic Resonance, Faculty of Natural Sciences Institute for Experimental Physics, Otto von Guericke University Magdeburg, Leipziger Str 44, Haus 01, 39120 Magdeburg, Germany
    MAGMA 21:73-86. 2008
    Single-shot echo planar imaging (EPI) acquisitions at 7T are challenging due to increased distortions, signal dropouts, RF-power requirements, and reduced T2*...
  87. ncbi Monitoring ankylosing spondylitis therapy by dynamic contrast-enhanced and diffusion-weighted magnetic resonance imaging
    Natasa Gaspersic
    Department of Rheumatology, University Medical Centre, Ljubljana, Slovenia
    Skeletal Radiol 37:123-31. 2008
    ..The aim was to assess the role of quantitative MRI in the evaluation of AS treatment efficacy...
  88. ncbi Clinical implications of increased fractional anisotropy in meningitis associated with brain abscess
    Kavindra Nath
    Department of Radiodiagnosis, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Comput Assist Tomogr 31:888-93. 2007
    ..To look for the clinical implications of increased cortical fractional anisotropy (FA) in meningitis patients associated with brain abscess...
  89. ncbi A preliminary study of the effects of trigger timing on diffusion tensor imaging of the human spinal cord
    P Summers
    Institute for Neuroradiology, University Hospital Zurich, Zurich, Switzerland
    AJNR Am J Neuroradiol 27:1952-61. 2006
    ..In this study, we examined the temporal dynamics of spinal cord motion and their impact on diffusion tensor image quality...
  90. ncbi 3D MRI in multiple sclerosis: a study of three sequences at 3 T
    R J Mills
    Department of Neurology, The Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    Br J Radiol 80:307-20. 2007
    ....
  91. ncbi Global and region-specific analyses of apparent diffusion coefficient in dentatorubral-pallidoluysian atrophy
    T Kin
    Department of Neurology, Nara Medical University, 840 Shijo Cho, Kashihara, Nara 634 8522, Japan
    AJNR Am J Neuroradiol 27:1463-6. 2006
    ..We attempted to quantify global and region-specific neurodegeneration in DRPLA using analysis of apparent diffusion coefficient (ADC) maps...
  92. ncbi Sensitivity-encoded diffusion tensor MR imaging of the cervical cord
    Mara Cercignani
    Neuroimaging Research Unit, Department of Neuroscience, Scientific Institute and University Ospedale San Raffaele, Via Olgettina 60, 20132 Milan, Italy
    AJNR Am J Neuroradiol 24:1254-6. 2003
    ..Off-resonance artifacts were notably reduced compared with those of full-FOV EPI sequences. This approach to diffusion tensor MR imaging of the cervical cord is promising for future, more extensive clinical applications...
  93. ncbi A consistent relationship between local white matter architecture and functional specialisation in medial frontal cortex
    T E J Behrens
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Neuroimage 30:220-7. 2006
    ....
  94. ncbi MRI of the abnormal cervical spinal cord using 2D spoiled gradient echo multiecho sequence (MEDIC) with magnetization transfer saturation pulse. A T2* weighted feasibility study
    P Held
    Department of Diagnostic Radiology, University of Regensburg, 93042 Regensburg, Germany
    J Neuroradiol 30:83-90. 2003
    ....
  95. ncbi Unbiased segmentation of diffusion-weighted magnetic resonance images of the brain using iterative clustering
    Andreas Hadjiprocopis
    NMR Research Unit, Department of Neuroinflammation, Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK
    Magn Reson Imaging 23:877-85. 2005
    ..The unbiased method proposed may provide a more accurate methodology of segmentation in the analysis of DWI-EPI images in conditions such as MS...
  96. ncbi MR imaging enhancement patterns as predictors of hemorrhagic transformation in acute ischemic stroke
    Katie D Vo
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA
    AJNR Am J Neuroradiol 24:674-9. 2003
    ..We sought to investigate gadolinium enhancement in acute ischemic stroke patients to determine their association with subsequent HT...
  97. pmc Pyramidal tract mapping by diffusion tensor magnetic resonance imaging in multiple sclerosis: improving correlations with disability
    M Wilson
    Division of Clinical Neurology, Queens Medical Centre, Nottingham University, Nottingham, UK
    J Neurol Neurosurg Psychiatry 74:203-7. 2003
    ..Diffusion tensor imaging (DTI) of the brain can provide unique information regarding the orientation and integrity of white matter tracts in vivo...
  98. ncbi Dependence of amygdala activation on echo time: results from olfactory fMRI experiments
    Tony Stöcker
    Institut fur Medizin, Forschungszentrum Julich, 52425 Julich, Germany
    Neuroimage 30:151-9. 2006
    ..The results are in good agreement with theoretical descriptions of the BOLD sensitivity under the influence of susceptibility gradients...
  99. ncbi Multiparametric MRI ISODATA ischemic lesion analysis: correlation with the clinical neurological deficit and single-parameter MRI techniques
    Panayiotis D Mitsias
    Department of Neurology, Henry Ford Health Sciences Center, Detroit, Michigan, USA
    Stroke 33:2839-44. 2002
    ....
  100. ncbi Variable precision registration via wavelets: optimal spatial scales for inter-subject registration of functional MRI
    J Suckling
    Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Neuroimage 31:197-208. 2006
    ..We conclude that major benefits in sensitivity to detect functional activation in multi-subject fMRI studies can be attained with an inhomogeneous deformation applied over appropriate spatial scales...
  101. ncbi Fiber tracking in the cervical spine and inferior brain regions with reversed gradient diffusion tensor imaging
    Henning U Voss
    Citigroup Biomedical Imaging Center, Weill Medical College of Cornell University, New York, NY 10021, USA
    Magn Reson Imaging 24:231-9. 2006
    ..Furthermore, uninterrupted white matter fiber tracts going from the cervical spine up to cortical areas, derived from data acquired in a single acquisition, are presented...

Research Grants62

  1. fMRI Technique Development for Substance Abuse Research
    Blaise Frederick; Fiscal Year: 2005
    ..The long term goals of this research are to provide a better understanding of the phenomenon of cocaine abuse so that better prevention and treatment strategies can be developed and evaluated. ..
  2. Artifact-Free Diffusion Mapping with Echo-Planar Imaging
    Nan kuei Chen; Fiscal Year: 2005
    ..A successful outcome from this study will generate a robust and rigorously validated diffusion mapping protocol free from EPI artifacts. ..
  3. Free-Breathing Perfusion MRI of the Abdomen with Predictive Motion Correction
    H Michael Gach; Fiscal Year: 2013
    ..using computer simulations and in vivo respiratory motion data;2) integrate the best RMP algorithms with 2D echo planar imaging (EPI) and 3D gradient and spin echo (GRASE) MRI to allow fast free-breathing MRI acquisitions of the ..
  4. High resolution 3D diffusion-weighted breast MRI
    Bruce L Daniel; Fiscal Year: 2012
    ..Eliminating gadolinium contrast material will reduce the duration, cost, risk and invasiveness of breast MRI, enabling MRI to be used more widely to screen for occult, early-stage, treatable breast cancer. ..
  5. Development of Sub-second 3D Pulse Sequences for FMRI in Neurosciences
    DAVID ALAN FEINBERG; Fiscal Year: 2010
    ..b>Echo planar imaging (EPI) is the most widely used fMRI pulse sequence, due to its speed and BOLD contrast, however EPI has ..
  6. MULTIPLEXED ECHO PLANAR IMAGING FOR NEUROSCIENCES
    DAVID ALAN FEINBERG; Fiscal Year: 2013
    ..b>Echo planar imaging (EPI) is the most widely used MRI technique used for neurosciences due to its extremely fast imaging speed ..
  7. Effect of HIV infection and antiretroviral therapy on cerebral autoregulation
    Souvik Sen; Fiscal Year: 2013
    ..Through the use of the unique resources and personnel at University of North Carolina, we have the opportunity to provide answers to important clinical and mechanistic questions in HIV and the risk for stroke. ..
  8. Combined shim-RF for improved high field MRI
    Lawrence L Wald; Fiscal Year: 2013
    ..The problem is particularly acute for fast sequences such as the echo planar imaging (EPI) needed for functional, perfusion and diffusion imaging...
  9. Adaptive Techniques for Robust High-Resolution Functional Magnetic Resonance Imag
    DANIEL STUART WELLER; Fiscal Year: 2013
    ..Altogether, we aim to provide novel acquisition and reconstruction techniques that are more robust to motion and observation noise and have greater resolution than conventional fMRI. ..
  10. TISSUE VIABILITY IN STROKE BY SODIUM MR IMAGING
    Keith Thulborn; Fiscal Year: 2003
    ..abstract_text> ..
  11. TISSUE VIABILITY IN STROKE BY SODIUM MR IMAGING
    Keith Thulborn; Fiscal Year: 2002
    ..abstract_text> ..
  12. Development of a Brain Template for Diffusion-Tensor MRI
    Konstantinos Arfanakis; Fiscal Year: 2009
    ....
  13. DIFFUSION/PERFUSION MRI OF ISCHEMIC PENUMBRA
    Robert Edelman; Fiscal Year: 1999
    ..These innovations include echo planar imaging (EPI), a class of MRI pulse sequences that permits imaging on the order on 100 ms, diffusion weighted ..
  14. SUPERHEATED DROP DETECTORS FOR DOSIMETRY IN RADIOTHERAPY
    Ravinder Nath; Fiscal Year: 2005
    ..microdroplets An automated technique for rapid pressure cycling and high-speed image acquisition using 3D-echo planar imaging and optical tomography will be used to improve statistical accuracy and spatial resolution...
  15. MR Diffusion Tensor Imaging of Prostate Cancer
    Daniel B Vigneron; Fiscal Year: 2010
    ..abstract_text> ..
  16. PERFUSION MR IMAGING OF RENAL ALLOGRAFT REJECTION
    SARDHA TALAGALA; Fiscal Year: 1999
    ..Perfusion characteristics of renal allografts measured perfusion MRI offer potential clinical application to diagnosis of AR. ..
  17. Diagnostic Imaging of Cerebral Blood Flow with MRI
    David Alsop; Fiscal Year: 2003
    ..These developments will make reliable CBF imaging by Arterial Spin Labeling a widely applicable technique for diagnostic imaging. ..
  18. Systematic Artifact Reduction in Auditory fMRI
    Thomas Talavage; Fiscal Year: 2009
    ..These benefits will provide greater confidence in location and extent of detected activity, significantly impacting human brain mapping, but also directly benefiting efforts at pre-surgical mapping. ..
  19. Improved Multimodal Acquisition and Processing System
    DONALD DUROUSSEAU; Fiscal Year: 2004
    ..abstract_text> ..
  20. BIOMEDICAL IMPLICATIONS OF MAGNETIC SUSCEPTIBILITY
    Thomas Brady; Fiscal Year: 2001
    ..The availability of real time echo planar imaging as a tool for the study of these questions continues to offer both new opportunities and scientific ..
  21. Improved imaging of brain white matter
    Adam Anderson; Fiscal Year: 2007
    ..2) To develop high spatial resolution DTI using navigated, multiple shot echo planar imaging. (3) To develop a time-efficient approach to DTI that uses a multiple-tensor model of diffusion in each ..
  22. ROBUST CONTRAST FOR AUTO--ANALYSIS OF CARDIAC MRI
    John Oshinski; Fiscal Year: 2000
    ..to control the effect of normal breathing during examination and, to provide greater coverage in less time, echo planar imaging. They proposed to compare diagnoses made from conventional and improved images and to compare automated ..
  23. 32-Channel Parallel Imaging 3Tesla MRI
    Alayar Kangarlu; Fiscal Year: 2009
    ..SPGR and echo planar imaging (EPI) will specially benefit from ability to achieve much shorter echo times (TE) and further enhance SNR ..
  24. DYNAMIC 3D TAGGED MRI OF THE CARDIAC CYCLE IN ISCHEMIA
    Elias Zerhouni; Fiscal Year: 1999
    ..We will also continue our clinical exploration of acute reperfused infarction in man with similar methods. ..
  25. Console upgrade for 4.7T Imaging and Spectroscopy System
    Martin Kushmerick; Fiscal Year: 2002
    ..Rapid scout imaging for checks on surface coil placement and state-of-the-art echo planar imaging to map the dynamics of muscle length changes during contraction are not possible now...
  26. 94T NMR SYSTEM
    J Vaughan; Fiscal Year: 1999
    ..Overall, this primate dedicated NMR system will provide state-of-the-art performance and capability for imaging of laboratory animals at the NERPRC. ..
  27. MRI OF HUMAN CORONARY ARTERIES
    Leon Kaufman; Fiscal Year: 1991
    ..Characterization of echo planar imaging of the human coronary arteries...
  28. ELECTROMAGNETIC REAL-TIME TRACKING DURING MRI SCANNING
    Erez Nevo; Fiscal Year: 1999
    ..abstract_text> ..
  29. PARALLEL SUPERSCALAR PROCESSING SYSTEM FOR NMR RESEARCH
    Justin Pearlman; Fiscal Year: 1991
    ....
  30. A QUIET, HIGH-PERFORMANCE, HIGH-FIELD MRI GRADIENT COIL
    F Doty; Fiscal Year: 2004
    ..The gradient coil will be switchable between a configuration optimized for functional MRI (fMRI) using Echo Planar Imaging (EPI) and one optimized for high-gradient techniques such as high-resolution diffusion-weighted microscopy ..
  31. A QUIET, HIGH-PERFORMANCE, HIGH-FIELD MRI GRADIENT COIL
    F Doty; Fiscal Year: 2001
    ..The gradient coil will be switchable between a configuration optimized for functional MRI (fMRI) using Echo Planar Imaging (EPI) and one optimized for high-gradient techniques such as high-resolution diffusion-weighted microscopy ..
  32. High-Throughput RF Coils for High-Field MRI
    F Doty; Fiscal Year: 2001
    ..The design will be compatible with EPI (Echo Planar Imaging) and will be suitable for use from 1 to 5 T...
  33. FUNCTIONAL MRI FOR NEUROSURGICAL PLANNING IN EPILEPSY
    R Constable; Fiscal Year: 2006
    ..It is noninvasive and has been shown to be able to localize cortical activity. However, the standard echo planar imaging fMR1 methods, based on the BOLD activation response, suffer from low spatial resolution, and sensitivity to ..
  34. Combined RT-shim & gradient system B-GA 12S
    Helene Benveniste; Fiscal Year: 2009
    ....
  35. High Fidelity fMRI
    Allen Song; Fiscal Year: 2007
    ..abstract_text> ..
  36. K-Space energy spectrum analysis for echo-planar imaging
    Nan kuei Chen; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  37. A Longitudinal 3-D MRSI Study of Infants at High Risk for Autism
    Stephen R Dager; Fiscal Year: 2010
    ....
  38. BRAIN METABOLISM AND TREATMENT OUTCOME IN PANIC DISORDER
    Stephen Dager; Fiscal Year: 2004
    ..abstract_text> ..
  39. A Diffusion-Based MRI Method to Detect Glioma Invasion
    KATHLEEN SCHMAINDA; Fiscal Year: 2008
    ..This comprehensive approach to brain tumor imaging should dramatically improve the treatment and prognosis for patients with brain tumors. [unreadable] [unreadable] [unreadable]..
  40. Dynamic Magnetic Resonance Inverse Imaging of the Human Brain
    Fa Hsuan Lin; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  41. Improved 3D MRI with cylindrical trajectories
    David Feinberg; Fiscal Year: 2004
    ..During the commercialization phase the developed set of pulse sequences will be ported for suitable hardware and software platforms of all major MR hardware manufacturers. ..
  42. MRI PULSE SEQUENCE DESIGNS FOR SUB-SECOND BRAIN IMAGING
    David Feinberg; Fiscal Year: 2001
    ..The most widely used approach to sub-second MRI, echo planar imaging (EPI), suffers from severe limitations...
  43. Evaluation of New Imaging Methodologies at 7T
    EWART HAACKE; Fiscal Year: 2007
    ..Many of the approaches developed and applied on this animal system are expected to have important clinical impact. All of these projects will substantially benefit from the proposed acquisition. [unreadable] [unreadable] [unreadable]..
  44. Real-Time Functional MRI with Automated Pattern Classification
    Stefan Posse; Fiscal Year: 2008
    ..The long-term goal of this project is to develop an automated fMRI analysis tool that will have significant commercial potential for clinical and research use. [unreadable] [unreadable] [unreadable]..
  45. Susceptibility Weighted Imaging (SWI)
    EWART MARK HAACKE; Fiscal Year: 2010
    ..Recently, SWI has also become available to the clinical world for every day use and therefore its continued technical development is of paramount importance for the proper diagnosis of these diseases in patients. ..
  46. Real-time FMRI at High Field / Automatic Classification
    Stefan Posse; Fiscal Year: 2005
    ..abstract_text> ..
  47. Odors maps in olfactory bulb by fMRI
    DEWAN SYED HYDER; Fiscal Year: 2006
    ..Activity of single glomeruli can help elucidate mechanisms of olfactory processing. ..
  48. Merit of MRI Perfusion Targets for Radiotherapy Planning
    KATHLEEN SCHMAINDA; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  49. PHYSIOLOGIC UNDERSTANDING OF FUNCTIONAL MRI
    Fahmeed Hyder; Fiscal Year: 2002
    ....
  50. MR Guided Transendocardial Angiogenic Agents
    Maythem Saeed; Fiscal Year: 2007
    ..abstract_text> ..
  51. Ultrasound-Guided MRI
    David Feinberg; Fiscal Year: 2005
    ..Ultrasound-guided MRI should permit dramatic improvements in imaging the heart or abdominal organs that are affected by physiological motion. ..
  52. Acoustic Interference on Attention in HIV Patients
    Dardo Tomasi; Fiscal Year: 2003
    ..More generally, this study will also improve the understanding of the neural effects of acoustic noise interference during fMRI studies in healthy populations. ..
  53. Dynamic Measurement of Brain Metabolism in Schizophrenia
    David Guilfoyle; Fiscal Year: 2005
    ..In addition, this technique will provide a new rapid method for evaluation of drug effects, and a potential method for detecting very early stages of the disease prior to the manifestation of a full-blown psychosis. ..
  54. Neural representations of social knowledge
    Jason Mitchell; Fiscal Year: 2005
    ..Together, these experiments will improve current understanding of autism, a prevalent developmental disorder characterized by pervasive deficits in social cognitive processing, e.g., representing the mental states of other people. ..
  55. The Structural Dependence of CRAZED Imaging
    DANIEL GOCHBERG; Fiscal Year: 2005
    ..We aim to clarify the factors that affect this dependence. ..
  56. CLINICAL NMR STUDIES AT 41T--A RESEARCH RESOURCE
    DONALD TWIEG; Fiscal Year: 2001
    ..These goals are intended to advance the state of the art in high field imaging and spectroscopy from a research curiousity to a powerful and clinically viable investigation tool. ..
  57. MONTE CARLO SIMULATION OF HIGH ENERGY PHOTON IMAGING
    Yuni Dewaraja; Fiscal Year: 2001
    ..Apart from quantification, this work will have applications in the design of future imaging systems for high energy photons. ..
  58. HE3 MR Diffusion & Low Dose CT Quantitation of Emphysema
    David Gierada; Fiscal Year: 2005
    ..In a third group of subjects, we will determine ADC and LD-QCT lung attenuation measurements at serial time points to assess for emphysema progression (Aim III). ..
  59. BROADBAND EPR SPECTROMETER WITH DIGITAL SUBSAMPLING
    James Hyde; Fiscal Year: 2002
    ..It is the only method that can detect the formation of free radicals in biology unambiguously. It contributes to health-related research at the basic fundamental level. ..
  60. PREVENTION OF SUICIDE IN THE ELDERLY
    George Alexopoulos; Fiscal Year: 2002
    ..Data will also be collected to document the impact of intervention on patient care, and on physician knowledge, attitudes, and satisfaction and test hypotheses derived from preliminary studies of the three IRCs. ..
  61. Neurochemical Challenge in Human Stroke Recovery
    RONALD LAZAR; Fiscal Year: 2008
    ..abstract_text> ..
  62. MAGIC - Magnetic Resonance Assessment of Gene Imaging Constructs
    Ralph Mason; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..