oximetry

Summary

Summary: The determination of oxygen-hemoglobin saturation of blood either by withdrawing a sample and passing it through a classical photoelectric oximeter or by electrodes attached to some translucent part of the body like finger, earlobe, or skin fold. It includes non-invasive oxygen monitoring by pulse oximetry.

Top Publications

  1. pmc A physiologic reduced oxygen protocol decreases the incidence of threshold retinopathy of prematurity
    Kenneth W Wright
    Cedars Sinai Medical Center, Los Angeles, California, USA
    Trans Am Ophthalmol Soc 104:78-84. 2006
  2. pmc Target ranges of oxygen saturation in extremely preterm infants
    Waldemar A Carlo
    N Engl J Med 362:1959-69. 2010
  3. ncbi Impact of extracranial contamination on regional cerebral oxygen saturation: a comparison of three cerebral oximetry technologies
    Sophie N Davie
    Department of Anesthesia and Perioperative Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    Anesthesiology 116:834-40. 2012
  4. pmc Neurodevelopmental outcomes in the early CPAP and pulse oximetry trial
    Yvonne E Vaucher
    Department of Pediatrics, University of California at San Diego, San Diego, California 92013, USA
    N Engl J Med 367:2495-504. 2012
  5. ncbi Pulse oximetry in pediatric practice
    Sotirios Fouzas
    Respiratory Unit, Department of Pediatrics, University Hospital of Patras, Rio, 265 04 Patras, Greece
    Pediatrics 128:740-52. 2011
  6. ncbi Can changes in clinical practice decrease the incidence of severe retinopathy of prematurity in very low birth weight infants?
    Lily C Chow
    Division of Neonatology, Department of Pediatrics, Cedars Sinai Medical Center and UCLA School of Medicine, Los Angeles, California, USA
    Pediatrics 111:339-45. 2003
  7. ncbi Prognostic value of desaturation during a 6-minute walk test in idiopathic interstitial pneumonia
    Vibha N Lama
    Department of Radiology, University of Michigan Health System, University of Michigan School of Public Health, Ann Arbor, MI 48109 0360, USA
    Am J Respir Crit Care Med 168:1084-90. 2003
  8. ncbi Oximetry, heart rate variability, and the diagnosis of mild-to-moderate acute mountain sickness
    Michael S Koehle
    School of Human Kinetics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Eur J Emerg Med 17:119-22. 2010
  9. pmc Evaluation of electrical and optical plethysmography sensors for noninvasive monitoring of hemoglobin concentration
    Justin P Phillips
    School of Engineering and Mathematical Sciences, City University London, Northampton Square, London EC1V 0HB, UK
    Sensors (Basel) 12:1816-26. 2012
  10. pmc Simultaneous mapping of temporally-resolved blood flow velocity and oxygenation in femoral artery and vein during reactive hyperemia
    Michael C Langham
    Laboratory for Structural NMR Imaging, Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, PA, USA
    J Cardiovasc Magn Reson 13:66. 2011

Detail Information

Publications324 found, 100 shown here

  1. pmc A physiologic reduced oxygen protocol decreases the incidence of threshold retinopathy of prematurity
    Kenneth W Wright
    Cedars Sinai Medical Center, Los Angeles, California, USA
    Trans Am Ophthalmol Soc 104:78-84. 2006
    ....
  2. pmc Target ranges of oxygen saturation in extremely preterm infants
    Waldemar A Carlo
    N Engl J Med 362:1959-69. 2010
    ..However, it is unclear what range of oxygen saturation is appropriate to minimize retinopathy without increasing adverse outcomes...
  3. ncbi Impact of extracranial contamination on regional cerebral oxygen saturation: a comparison of three cerebral oximetry technologies
    Sophie N Davie
    Department of Anesthesia and Perioperative Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    Anesthesiology 116:834-40. 2012
    Cerebral oximetry is a noninvasive technology using near-infrared spectroscopy (NIRS) to estimate regional cerebral oxygen saturation...
  4. pmc Neurodevelopmental outcomes in the early CPAP and pulse oximetry trial
    Yvonne E Vaucher
    Department of Pediatrics, University of California at San Diego, San Diego, California 92013, USA
    N Engl J Med 367:2495-504. 2012
    ..A lower (vs. higher) target range of oxygen saturation was associated with a lower rate of severe retinopathy but higher mortality. We now report longer-term results from our prespecified hypotheses...
  5. ncbi Pulse oximetry in pediatric practice
    Sotirios Fouzas
    Respiratory Unit, Department of Pediatrics, University Hospital of Patras, Rio, 265 04 Patras, Greece
    Pediatrics 128:740-52. 2011
    The introduction of pulse oximetry in clinical practice has allowed for simple, noninvasive, and reasonably accurate estimation of arterial oxygen saturation...
  6. ncbi Can changes in clinical practice decrease the incidence of severe retinopathy of prematurity in very low birth weight infants?
    Lily C Chow
    Division of Neonatology, Department of Pediatrics, Cedars Sinai Medical Center and UCLA School of Medicine, Los Angeles, California, USA
    Pediatrics 111:339-45. 2003
    ....
  7. ncbi Prognostic value of desaturation during a 6-minute walk test in idiopathic interstitial pneumonia
    Vibha N Lama
    Department of Radiology, University of Michigan Health System, University of Michigan School of Public Health, Ann Arbor, MI 48109 0360, USA
    Am J Respir Crit Care Med 168:1084-90. 2003
    ..We conclude that knowledge of desaturation during a 6-minute walk test adds prognostic information for patients with usual interstitial pneumonia and nonspecific interstitial pneumonia...
  8. ncbi Oximetry, heart rate variability, and the diagnosis of mild-to-moderate acute mountain sickness
    Michael S Koehle
    School of Human Kinetics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Eur J Emerg Med 17:119-22. 2010
    ..In conclusion, in patients with SpO2 of 86% or more at 4380 m or higher, the likelihood of AMS is low. Diastolic blood pressure correlated with AMS severity, whereas heart rate variability was not useful in the diagnosis of AMS...
  9. pmc Evaluation of electrical and optical plethysmography sensors for noninvasive monitoring of hemoglobin concentration
    Justin P Phillips
    School of Engineering and Mathematical Sciences, City University London, Northampton Square, London EC1V 0HB, UK
    Sensors (Basel) 12:1816-26. 2012
    ..The ratio PPG:CPG is invariant to pulse pressure. This quantity is discussed as a possible index of in vivo hemoglobin concentration...
  10. pmc Simultaneous mapping of temporally-resolved blood flow velocity and oxygenation in femoral artery and vein during reactive hyperemia
    Michael C Langham
    Laboratory for Structural NMR Imaging, Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, PA, USA
    J Cardiovasc Magn Reson 13:66. 2011
    ..Here we demonstrate the feasibility of a simultaneous measurement of blood flow and HbO2 in the femoral circulation as part of a single procedure...
  11. pmc Two new "protected" oxyphors for biological oximetry: properties and application in tumor imaging
    Tatiana V Esipova
    Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States
    Anal Chem 83:8756-65. 2011
    ..These experiments revealed that changes in isofluorane concentration significantly affect tissue oxygenation...
  12. ncbi Retinal oxygen saturation is altered in diabetic retinopathy
    Sveinn Hakon Hardarson
    Department of Ophthalmology, University of Iceland LandspítalidUniversity Hospital, Reykjavik, Iceland
    Br J Ophthalmol 96:560-3. 2012
    ..Retinal oxygen metabolism is thought to be affected in diabetic retinopathy. The aim of this study was to test whether retinal vessel oxygen saturation is different in patients with diabetic retinopathy from that in healthy controls...
  13. ncbi Multidistance probe arrangement to eliminate artifacts in functional near-infrared spectroscopy
    Toru Yamada
    National Institute of Advanced Industrial Science and Technology, Neuroscience Research Institute, 1 1 1 Umezono Central 2, Tsukuba, Ibaraki 305 8568, Japan
    J Biomed Opt 14:064034. 2009
    ..A statistically significant increase in oxygenated hemoglobin and decrease in deoxygenated hemoglobin are simultaneously observed at the contralateral primary motor area...
  14. ncbi Determinants of cerebral oximetry in patients undergoing off-pump coronary artery bypass grafting: an observational study
    Stefan Moritz
    Department of Anaesthesiology, University Hospital Regensburg, Regensburg, Germany
    Eur J Anaesthesiol 27:542-9. 2010
    ..The present study investigated whether positioning of the heart during off-pump coronary artery bypass grafting leads to changes in regional cerebral oxygen saturation measured by near infrared spectroscopy...
  15. ncbi Quantification of left-to-right shunting in adult congenital heart disease: phase-contrast cine MRI compared with invasive oximetry
    K Debl
    Klinik und Poliklinik fur Innere Medizin II, Universitatsklinikum Regensburg, Germany
    Br J Radiol 82:386-91. 2009
    ..compared phase-contrast cine magnetic resonance imaging (PC-MRI), a non-invasive imaging technique, with invasive oximetry for the measurement of shunt volumes during cardiac catheterisation in adults with left-to-right shunting...
  16. pmc Pulse oximetry, severe retinopathy, and outcome at one year in babies of less than 28 weeks gestation
    W Tin
    Department of Paediatrics, South Cleveland Hospital, Middlesbrough TS4 3BW, UK
    Arch Dis Child Fetal Neonatal Ed 84:F106-10. 2001
    ....
  17. ncbi Pulse oxygen saturation levels and arterial oxygen tension values in newborns receiving oxygen therapy in the neonatal intensive care unit: is 85% to 93% an acceptable range?
    Armando Castillo
    Division of Neonatal Perinatal Medicine, Emory University, Atlanta, Georgia, USA
    Pediatrics 121:882-9. 2008
    ....
  18. ncbi False alarms and sensitivity of conventional pulse oximetry versus the Masimo SET technology in the pediatric postanesthesia care unit
    S Malviya
    Department of Anesthesiology, The University of Michigan Health System, Ann Arbor, Michigan 48109 0211, USA
    Anesth Analg 90:1336-40. 2000
    We compared the incidence and duration of false alarms (FA)and the sensitivity of conventional pulse oximetry (CPO) with Masimo Signal Extraction Technology (Masimo SET; Masimo Corporation, Irvine, CA) in children in the postanesthesia ..
  19. ncbi Brain oxymetry in the operating room: current status and future directions with particular regard to cytochrome oxidase
    Yasuyuki Kakihana
    Kagoshima University Hospital, Division of Intensive Care Medicine, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    J Biomed Opt 13:033001. 2008
    ..NIRS appears to be a promising technology, but additional investigations are required to establish its clinical efficacy and justify its routine use during operative and perioperative periods...
  20. ncbi Use of a peripheral perfusion index derived from the pulse oximetry signal as a noninvasive indicator of perfusion
    Alexandre Pinto Lima
    Department of Intensive Care Gelre Hospital, Apeldoorn, The Netherlands
    Crit Care Med 30:1210-3. 2002
    ..Recently, the pulse oximetry signal has been suggested to reflect changes in peripheral perfusion...
  21. ncbi Influence of patient variables and sensor location on regional cerebral oxygen saturation measured by INVOS 4100 near-infrared spectrophotometers
    Katsuyoshi Kishi
    Departments of Anesthesiology, Bell Land General Hospital, Osaka, Japan
    J Neurosurg Anesthesiol 15:302-6. 2003
    ..These data indicate that patient age, hemoglobin concentration at the measurement, and sensor location can affect rSO2 values...
  22. ncbi New technology for noninvasive brain monitoring: continuous cerebral oximetry
    A Casati
    Department of Anesthesiology, Ospedale Maggiore, University of Parma, Parma, Italy
    Minerva Anestesiol 72:605-25. 2006
    ..The aim of this review is to provide an overview on relevant technological issues of cerebral oximetry, describe a systematic approach to its use, and summarize current information on its possible impact on our daily ..
  23. ncbi Noninvasive quantification of left-to-right shunt in pediatric patients: phase-contrast cine magnetic resonance imaging compared with invasive oximetry
    P Beerbaum
    Clinic for Congenital Heart Disease, Heart and Diabetes Center, North Rhine Westfalia, Ruhr University Bochum, Germany
    Circulation 103:2476-82. 2001
    ..Blood flow can be quantified noninvasively by phase-contrast cine MRI (PC-MRI) in adults. Little is known about the feasibility of the method in children with congenital heart disease...
  24. ncbi Evaluation of a cerebral oximeter as a monitor of cerebral ischemia during carotid endarterectomy
    S K Samra
    Departments of Anesthesiology and Surgery, University of Michigan Health System, Ann Arbor, Michigan, USA
    Anesthesiology 93:964-70. 2000
    ....
  25. ncbi Continuous, noninvasive, and localized microvascular tissue oximetry using visible light spectroscopy
    David A Benaron
    Biomedical Optics Laboratory, and Department of Pediatrics, Stanford Hospital and Livermore Veterans Affairs Medical Center, Palo Alto, California 94305, USA
    Anesthesiology 100:1469-75. 2004
    The authors evaluated the ability of visible light spectroscopy (VLS) oximetry to detect hypoxemia and ischemia in human and animal subjects...
  26. ncbi Review article: cerebral near-infrared spectroscopy in adults: a work in progress
    Arnab Ghosh
    Department of Neurocritical Care, Box 30, The National Hospital for Neurology and Neurosurgery, University College London Hospitals, Queen Square, London WC1N 3BGUK
    Anesth Analg 115:1373-83. 2012
    ..NIRS has many potential advantages over other neuromonitoring techniques, but further investigation and technological advances are necessary before it can be introduced more widely into clinical practice...
  27. ncbi Near-infrared spectroscopy as an index of brain and tissue oxygenation
    J M Murkin
    Department of Anesthesiology and Perioperative Medicine, University Hospital LHSC, University of Western Ontario, Rm C3 112, 339 Windermere Rd, London, ON, Canada N6A 5A5
    Br J Anaesth 103:i3-13. 2009
    ..The current clinical availability of several non-invasive near-infrared spectroscopy (NIRS)-based cerebral oximetry devices represents a potentially important development for the detection of cerebral ischaemia...
  28. ncbi The efficacy of perfusion index as an indicator for intravascular injection of epinephrine-containing epidural test dose in propofol-anesthetized adults
    Hany A Mowafi
    Department of Anesthesiology, King Fahd University Hospital, PO Box 40081, Al Khobar 31952, Saudi Arabia
    Anesth Analg 108:549-53. 2009
    ....
  29. ncbi Masimo signal extraction pulse oximetry
    J M Goldman
    Masimo Corporation, 2852 Kelvin Avenue, Irvine, CA 92614, USA
    J Clin Monit Comput 16:475-83. 2000
    To describe a new pulse oximetry technology and measurement paradigm developed by Masimo Corporation.
  30. ncbi Reduced cerebral oxygen saturation measured by absolute cerebral oximetry during thoracic surgery correlates with postoperative complications
    R Kazan
    ITAG Intelligent Technology in Anaesthesia Group, Department of Anaesthesiology, Montreal General Hospital, McGill University, Montreal, Canada
    Br J Anaesth 103:811-6. 2009
    ..Regional cerebral oxygen saturation (S(ct)O(2)) has recently been shown to decrease significantly during thoracic surgery. The present study investigates whether these desaturations are related to postoperative complications...
  31. ncbi Estimation of respiratory rate from photoplethysmogram data using time-frequency spectral estimation
    Ki H Chon
    Department of Biomedical Engineering, State University of New York SUNY at Stony Brook, Stony Brook, NY 11794 USA
    IEEE Trans Biomed Eng 56:2054-63. 2009
    ..3 s on 1 min of data using a MATLAB implementation) to extract breathing rates that varied from 12-36 breaths/min...
  32. ncbi Photonic textiles for pulse oximetry
    Markus Rothmaier
    Empa, Laboratory for Protection and Physiology, Lerchenfeldstrasse 5, 9014 St Gallen, Switzerland
    Opt Express 16:12973-86. 2008
    ..Our results show that textile-based oximetry is feasible with sufficient data quality and its potential as a wearable health monitoring device is promising.
  33. ncbi Nocturnal monitoring of home non-invasive ventilation: the contribution of simple tools such as pulse oximetry, capnography, built-in ventilator software and autonomic markers of sleep fragmentation
    Jean Paul Janssens
    Centre antituberculeux, Division of Pulmonary Diseases, Geneva University Hospital, Rue Gabrielle Perret Gentil 4, 1211 Geneva 14, Switzerland
    Thorax 66:438-45. 2011
    ..Simple tools can provide important information when monitoring NIV. Pulse oximetry is important to ensure that adequate oxygen saturation is provided and to detect either prolonged or short and ..
  34. ncbi Percutaneous nocturnal oximetry in amyotrophic lateral sclerosis: periodic desaturation
    Mamede de Carvalho
    Department of Neurology, Hospital de Santa Maria, Lisbon, Portugal
    Amyotroph Lateral Scler 10:154-61. 2009
    Percutaneous nocturnal oximetry (PNO) is useful to screen respiratory function in amyotrophic lateral sclerosis (ALS). PNO recordings of some patients disclose a periodical pattern of O(2) desaturation (PP), whose significance is unknown...
  35. pmc Pulse-oximetry accurately predicts lung pathology and the immune response during influenza infection
    David Verhoeven
    Department of Surgery, University of Maryland School of Medicine, Baltimore, MD 21210, USA
    Virology 390:151-6. 2009
    ..We found blood oxygen levels to be a more accurate assessment than weight-loss morbidity in predicting lung pathology in hosts infected with different viral doses, and in assessing immune-mediated viral clearance in the lung...
  36. ncbi Pulse oximetry screening for critical congenital heart defects in asymptomatic newborn babies: a systematic review and meta-analysis
    Shakila Thangaratinam
    Women s Health Research Unit, Centre for Primary Care and Public Health, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Lancet 379:2459-64. 2012
    ..We assessed the performance of pulse oximetry as a screening method for the detection of critical congenital heart defects in asymptomatic newborn babies.
  37. pmc From system to organ to cell: oxygenation and perfusion measurement in anesthesia and critical care
    Patrick Schober
    Department of Anaesthesiology, VU University Medical Center, De Boelelaan 1117, 1007 MB, Amsterdam, The Netherlands
    J Clin Monit Comput 26:255-65. 2012
    ..This article reviews the basic physiology of oxygen uptake and delivery to tissues as well as the options to monitor determinants of oxygenation at different stages from the alveolus to the cell...
  38. ncbi Oxygen desaturation index from nocturnal oximetry: a sensitive and specific tool to detect sleep-disordered breathing in surgical patients
    Frances Chung
    Department of Anesthesia, University Health Network, University of Toronto, 399, Bathurst Street, Toronto, ON, Canada M5T 2S8
    Anesth Analg 114:993-1000. 2012
    It is impractical to perform polysomnography (PSG) in all surgical patients suspected of having sleep disordered breathing (SDB). We investigated the role of nocturnal oximetry in diagnosing SDB in surgical patients.
  39. ncbi Noninvasive cerebral oximetry: is there light at the end of the tunnel?
    David Highton
    Department of Neurocritical Care, The National Hospital for Neurology and Neurosurgery, University College London Hospitals, Queen Square, London, UK
    Curr Opin Anaesthesiol 23:576-81. 2010
    ..This review will briefly describe the principles of NIRS and examine current evidence for its clinical application as a monitor of the adequacy of cerebral oxygenation in adults...
  40. ncbi Tissue oximetry monitoring in microsurgical breast reconstruction decreases flap loss and improves rate of flap salvage
    Samuel J Lin
    Department of Surgery, Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Boston, Mass 02215, USA
    Plast Reconstr Surg 127:1080-5. 2011
    ..Tissue oximeter monitoring offers an objective method for detecting vascular compromise with the measurement of tissue oxygen saturation and real-time flap perfusion...
  41. ncbi Nonlinear characteristics of blood oxygen saturation from nocturnal oximetry for obstructive sleep apnoea detection
    D Alvarez
    ETS Ingenieros de Telecomunicación, Campus Miguel Delibes, Camino del Cementerio s n, 47011 Valladolid, Spain
    Physiol Meas 27:399-412. 2006
    Nocturnal oximetry is an attractive option for the diagnosis of obstructive sleep apnoea (OSA) syndrome because of its simplicity and low cost compared to polysomnography (PSG)...
  42. ncbi Prediction of cognitive dysfunction and patients' outcome following valvular heart surgery and the role of cerebral oximetry
    Seong Wook Hong
    Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, 134 Shinchon dong, Seadaemun Ku, Seoul 120 752, South Korea
    Eur J Cardiothorac Surg 33:560-5. 2008
    ..Cerebral oximetry noninvasively measures regional cerebral oxygen saturation (rSO(2)) and significant correlation has been reported ..
  43. ncbi Achieving targeted pulse oximetry values in preterm infants in the delivery room
    Bheru Gandhi
    Division of Neonatology, University of California San Diego Medical Center, San Diego, CA 92103, USA
    J Pediatr 163:412-5. 2013
    ....
  44. pmc Assessing diabetic foot ulcer development risk with hyperspectral tissue oximetry
    Dmitry Yudovsky
    University of California, Los Angeles, Henry Samueli School of Engineering and Applied Science Biomedical Inter Department Program, Los Angeles, California 90095 1597, USA
    J Biomed Opt 16:026009. 2011
    ..We aim to assess the use of hyperspectral tissue oximetry in predicting the risk of diabetic foot ulcer formation...
  45. ncbi Accuracy of oximetry with thermistor (OxiFlow) for diagnosis of obstructive sleep apnea and hypopnea
    M A Baltzan
    Respiratory Division, McGill University Health Centre (Royal Victoria Hospital Site, Montreal, Quebec, Canada
    Sleep 23:61-9. 2000
    ..the diagnostic accuracy for obstructive sleep apnea and hypopnea (OSAH) of the OxiFlow (OF) device which combines oximetry with recording of thermistor airflow...
  46. ncbi The effect of averaging time on oximetry values in the premature infant
    Sally Jasmine Maia Ahmed
    Section of Neonatology and Developmental Biology, Departmentof Pediatrics, University of Arizona, Tucson, Arizona 85724, USA
    Pediatrics 125:e115-21. 2010
    ..The effect of a pulse oximeter's averaging time on time spent by premature infants in established saturation ranges, as well as on desaturation events, has not previously been reported...
  47. ncbi Real-time continuous monitoring of cerebral blood flow autoregulation using near-infrared spectroscopy in patients undergoing cardiopulmonary bypass
    Kenneth Brady
    Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Hospital, Baltimore, MD, USA
    Stroke 41:1951-6. 2010
    ..This study compares the accuracy of real-time cerebral blood flow autoregulation monitoring using near-infrared spectroscopy with that of transcranial Doppler...
  48. ncbi Pulse oximetry screening for congenital heart defects in newborn infants (PulseOx): a test accuracy study
    Andrew K Ewer
    University of Birmingham, School of Clinical and Experimental Medicine, Birmingham, UK
    Lancet 378:785-94. 2011
    ..We prospectively assessed the accuracy of pulse oximetry as a screening test for congenital heart defects.
  49. pmc Domiciliary pulse-oximetry at exacerbation of chronic obstructive pulmonary disease: prospective pilot study
    John R Hurst
    Academic Unit of Respiratory Medicine, Royal Free Campus, UCL Medical School, London, UK
    BMC Pulm Med 10:52. 2010
    ..We assessed the ability of domiciliary pulse oximetry to achieve this.
  50. ncbi Wavelength selection for low-saturation pulse oximetry
    P D Mannheimer
    Nellcor Puritan Bennett, Pleasanton, CA 94588, USA
    IEEE Trans Biomed Eng 44:148-58. 1997
    ..At high saturation these conditions are optimally met with 660 and 900 nm band emitters, while at low saturation 735 and 890 nm provide better performance...
  51. pmc Double-layer estimation of intra- and extracerebral hemoglobin concentration with a time-resolved system
    Louis Gagnon
    Institut de Génie Biomédical, Ecole Polytechnique de Montreal, C P 6079, Succ Centre Ville, Montreal, Quebec H3C 3A7, Canada
    J Biomed Opt 13:054019. 2008
    ..We observed a noticeable intersubject variability of the hemoglobin concentrations, but constant values for the cerebral hemoglobin oxygen saturation...
  52. ncbi Baseline cerebral oximetry values in elderly patients with hip fractures: a prospective observational study
    Georgios Papadopoulos
    Department of Anaesthesiology and Postoperative Intensive Care, University of Ioannina School of Medicine, Ioannina, Greece
    Injury 42:1328-32. 2011
    ..This study was conducted to evaluate baseline cerebral tissue regional oxygen saturation (rSO(2)) values and identify risk factors related to severe rSO(2) reductions in elderly patients with hip fractures...
  53. ncbi Prognostic significance of tumor oxygenation in humans
    Sydney M Evans
    School of Medicine, Department of Radiation Oncology, 195 John Morgan Building, University of Pennsylvania, Philadelphia, PA 19104, USA
    Cancer Lett 195:1-16. 2003
    ..These considerations are made in light of our specific hypotheses that hypoxia should be measured as a continuum, not a binary measurement and that moderate, not severe hypoxia is of great biological consequence...
  54. pmc Noninvasive optical quantification of absolute blood flow, blood oxygenation, and oxygen consumption rate in exercising skeletal muscle
    Katelyn Gurley
    University of Kentucky, Center for Biomedical Engineering, Lexington, Kentucky 40506, USA
    J Biomed Opt 17:075010. 2012
    ....
  55. ncbi Utility of pulse oximetry screening for hepatopulmonary syndrome
    Miguel R Arguedas
    Liver Center, Division of Gastroenterology and Hepatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Clin Gastroenterol Hepatol 5:749-54. 2007
    ..However, no specific screening guidelines are established. We evaluated pulse oximetry with contrast echocardiography in detecting hepatopulmonary syndrome in a cohort of patients undergoing ..
  56. ncbi Oxygen saturation in branch retinal vein occlusion
    Sveinn Hakon Hardarson
    Department of Ophthalmology, University of Iceland Landspitali The National University Hospital of Iceland, Reykjavik, Iceland
    Acta Ophthalmol 90:466-70. 2012
    ..The aim of this study was to test whether oxygen saturation in retinal blood vessels is affected by branch retinal vein occlusion (BRVO)...
  57. ncbi Three-year experience using near infrared spectroscopy tissue oximetry monitoring of free tissue transfers
    Matthew H Steele
    Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA
    Ann Plast Surg 66:540-5. 2011
    ..The patients were divided into 2 cohorts: conventional monitoring (group 1) and conventional monitoring plus NIRS oximetry (group 2). Overall flap survival was 90.6% in group 1 and 98.7% in group 2 (P = 0.05)...
  58. ncbi Evaluation of a new combined transcutaneous measurement of PCO2/pulse oximetry oxygen saturation ear sensor in newborn patients
    Vera Bernet-Buettiker
    Department of Neonatology, University Children s Hospital, Zurich, Switzerland
    Pediatrics 115:e64-8. 2005
    ..Recently, a new sensor for combined assessment of pulse oximetry oxygen saturation (Spo(2)) and Ptcco(2) has been introduced (TOSCA Monitor; Linde Medical Sensors, Basel, ..
  59. ncbi Effects of skin pigmentation on pulse oximeter accuracy at low saturation
    Philip E Bickler
    Department of Anesthesia and Perioperative Care, University of California at San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
    Anesthesiology 102:715-9. 2005
    ..It is uncertain whether skin pigmentation affects pulse oximeter accuracy at low HbO2 saturation...
  60. ncbi Simultaneous measurement of rat brain cortex PtO2 using EPR oximetry and a fluorescence fiber-optic sensor during normoxia and hyperoxia
    JULIA A O'HARA
    EPR Center for the Study of Viable Systems, Dartmouth Medical School, Hanover, NH 03755, USA
    Physiol Meas 26:203-13. 2005
    Electron paramagnetic resonance (EPR) oximetry is a promising, relatively non-invasive method of monitoring tissue partial pressure of oxygen (PtO(2)) that has proven useful in following changes in PtO(2) under various physiologic and ..
  61. ncbi Prediction of the apnea-hypopnea index from overnight pulse oximetry
    Ulysses J Magalang
    Division of Pulmonary, Critical Care, and Sleep Medicine, University at Buffalo, New York, USA
    Chest 124:1694-701. 2003
    s: To compare the relative usefulness of the different indexes derived from pulse oximetry in the diagnosis of obstructive sleep apnea (OSA), and to determine if a combination of these indexes improves the prediction of the apnea-hypopnea ..
  62. pmc Diffuse optical monitoring of repeated cerebral ischemia in mice
    Yu Shang
    Center for Biomedical Engineering, University of Kentucky, Lexington, Kentucky 40506, USA
    Opt Express 19:20301-15. 2011
    ..With the progress of repeated 2-minute bi-CCA occlusions over days, a longitudinal decline in the magnitudes of CBF reduction was observed, indicating the brain adaptation to cerebral ischemia through the repeated preconditioning...
  63. ncbi Dark skin decreases the accuracy of pulse oximeters at low oxygen saturation: the effects of oximeter probe type and gender
    John R Feiner
    Department of Anesthesia and Perioperative Care, University of California at San Francisco, San Francisco, California 94143 0648, USA
    Anesth Analg 105:S18-23, tables of contents. 2007
    Pulse oximetry may overestimate arterial oxyhemoglobin saturation (Sao2) at low Sao2 levels in individuals with darkly pigmented skin, but other factors, such as gender and oximeter probe type, remain less studied.
  64. ncbi Retinal oximetry images must be standardized: a methodological analysis
    Olafur Palsson
    University of Iceland, National University Hospital, Reykjavik, Iceland
    Invest Ophthalmol Vis Sci 53:1729-33. 2012
    Retinal vessel oximetry is a new technology and needs detailed methodological scrutiny...
  65. ncbi Retinal vessel oximetry-calibration, compensation for vessel diameter and fundus pigmentation, and reproducibility
    Martin Hammer
    University of Jena, Department of Ophthalmology, Jena, Germany
    J Biomed Opt 13:054015. 2008
    ..A simple system for noninvasive optical oximetry, consisting of a special filter in a fundus camera and software, was introduced...
  66. ncbi Near-infrared spectroscopy: a methodology-focused review
    Adelina Pellicer
    Department of Neonatology, La Paz University Hospital, Paseo de la Castellana 261, E 28046 Madrid, Spain
    Semin Fetal Neonatal Med 16:42-9. 2011
    ..The future beyond the scope of NIRS and potential lines of research will also be discussed...
  67. ncbi Noninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery
    Gregory W Fischer
    Department of Anesthesiology, Mount Sinai School of Medicine, Mount Sinai Medical Center, New York, NY 10029, USA
    J Thorac Cardiovasc Surg 141:815-21. 2011
    ..Cerebral oximetry is a noninvasive technology that can monitor the regional oxygen saturation of the frontal cortex...
  68. ncbi Dorzolamide-timolol combination and retinal vessel oxygen saturation in patients with glaucoma or ocular hypertension
    S Traustason
    Department of Ophthalmology, University of Iceland, Reykjavik, Iceland
    Br J Ophthalmol 93:1064-7. 2009
    ..To examine whether the addition of dorzolamide to timolol monotherapy influences oxygen saturation in the human retina...
  69. ncbi Diabetic patients with retinopathy show increased retinal venous oxygen saturation
    Martin Hammer
    Department of Ophthalmology, University of Jena, Bachstr 18, 07740, Jena, Germany
    Graefes Arch Clin Exp Ophthalmol 247:1025-30. 2009
    ..Longstanding diabetes mellitus results in a disturbed microcirculation. A new imaging oximeter was used to investigate the effect of this disturbance on retinal vessel oxygen saturation...
  70. ncbi Cerebral oximetry during carotid clamping: is blood pressure raising necessary?
    Enrico Giustiniano
    Department of Anesthesia and Intensive Care Unit, Humanitas Clinical Institute, Rozzano, Milan, Italy
    J Cardiovasc Med (Hagerstown) 11:522-8. 2010
    ..Cerebral oximetry (regional cerebral oxygen saturation, rSO2) measurement can ascertain whether brain perfusion is adequate...
  71. ncbi Oxygen saturation in central retinal vein occlusion
    Sveinn Hakon Hardarson
    Department of Ophthalmology, University of Iceland Landspítali University Hospital, Reykjavik, Iceland
    Am J Ophthalmol 150:871-5. 2010
    ..To test whether oxygen saturation is affected in retinal blood vessels in patients with central retinal vein occlusion (CRVO)...
  72. ncbi The accuracy of noninvasive and continuous total hemoglobin measurement by pulse CO-Oximetry in human subjects undergoing hemodilution
    Mark R Macknet
    Department of Anesthesiology, Loma Linda University, Loma Linda, California, USA
    Anesth Analg 111:1424-6. 2010
    Total hemoglobin (tHb) is one the most frequently ordered laboratory measurements. Pulse CO-Oximetry™ (Masimo Corp., Irvine, CA) is a multi-wavelength spectrophotometric method for noninvasive and continuous hemoglobin monitoring (SpHb)...
  73. ncbi Cerebral oxygen desaturation events assessed by near-infrared spectroscopy during shoulder arthroscopy in the beach chair and lateral decubitus positions
    Glenn S Murphy
    Department of Anesthesiology, NorthShore University Healthsystem, University of Chicago Pritzker School of Medicine, 2650 Ridge Ave, Evanston, IL 60201, USA
    Anesth Analg 111:496-505. 2010
    ..In this investigation, we sought to determine the incidence of cerebral desaturation events (CDEs) during shoulder arthroscopy in the BCP or lateral decubitus position (LDP)...
  74. ncbi Oxygen saturation and heart rate during delivery room resuscitation of infants <30 weeks' gestation with air or 100% oxygen
    J A Dawson
    Neonatal Services, The Royal Women s Hospital, 20 Flemington Road, Parkville, VIC 3052, Australia
    Arch Dis Child Fetal Neonatal Ed 94:F87-91. 2009
    ..Because of concerns about harmful effects of 100% oxygen on newborn infants, air has started to be used for resuscitation in the delivery room...
  75. ncbi Validation of pulse oximetry during progressive normobaric hypoxia utilizing a portable chamber
    Jon C Kolb
    Faculty of Kinesiology, Univ of Calgary, Canada
    Can J Appl Physiol 29:3-15. 2004
    Validation of pulse oximetry in commercially available normobaric hypoxic chambers (NHC) has not been previously reported...
  76. ncbi Brain monitoring in neonates
    Mona C Toet
    Department of Neonatology, Wilhelmina Children s Hospital UMC, Utrecht, The Netherlands
    Early Hum Dev 85:77-84. 2009
    ..Cerebral oximetry records regional saturation of the brain using Near Infrared Spectroscopy (NIRS) and provides a non-invasive ..
  77. ncbi The effects of ketamine-xylazine anesthesia on cerebral blood flow and oxygenation observed using nuclear magnetic resonance perfusion imaging and electron paramagnetic resonance oximetry
    H Lei
    NMR Research Center, Department of Diagnostic Radiology, Dartmouth Medical School, Hanover, NH 03755, USA
    Brain Res 913:174-9. 2001
    ..magnetic resonance (NMR) perfusion imaging and cortical P(t)O(2) using electron paramagnetic resonance (EPR) oximetry in the forebrain of rats under isoflurane, ketamine, ketamine-xylazine and isoflurane-xylazine anesthesia...
  78. ncbi Reliability of conventional and new pulse oximetry in neonatal patients
    William W Hay
    Department of Pediatrics, The Neonatal Clinical Research Center, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Perinatol 22:360-6. 2002
    Pulse oximetry is widely used in the NICU, but clinicians often distrust the displayed values during patient motion, i.e., questionable oxygen saturation (SpO(2)) and pulse rate (PR) values...
  79. ncbi Epidemiology of hypoxaemia in children with acute lower respiratory infection
    J M Lozano
    Department of Paediatrics, School of Medicine, Javeriana University, Bogota, Colombia
    Int J Tuberc Lung Dis 5:496-504. 2001
    ....
  80. ncbi Hypoxaemia in acute stroke is frequent and worsens outcome
    Anne M Rowat
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK
    Cerebrovasc Dis 21:166-72. 2006
    ..Hypoxaemia in the acute phase of stroke might damage the ischaemic penumbra and worsen clinical outcome. We determined the frequency of hypoxaemia on admission with stroke and assessed whether it was related to outcome...
  81. ncbi Global operating theatre distribution and pulse oximetry supply: an estimation from reported data
    Luke M Funk
    Department of Health Policy and Management, Harvard School of Public Health, Boston, MA 02115, USA
    Lancet 376:1055-61. 2010
    ..We estimated the global distribution of operating theatres and quantified the availability of pulse oximetry, which is an essential monitoring device during surgery and a potential measure of operating theatre resources.
  82. ncbi Preoperative cerebral oxygen saturation and clinical outcomes in cardiac surgery
    Matthias Heringlake
    Cardiac Anesthesia Unit, Department of Anesthesiology, University of Lubeck, Lubeck, Germany
    Anesthesiology 114:58-69. 2011
    ..The current study was designed to determine the relation between preoperative cerebral oxygen saturation (Sco2), variables of cardiopulmonary function, mortality, and morbidity in a heterogeneous cohort of cardiac surgery patients...
  83. ncbi Utility of the photoplethysmogram in circulatory monitoring
    Andrew Reisner
    Department of Medicine, Division of Emergency Medicine, Harvard Medical School, Boston, Massachusetts, USA
    Anesthesiology 108:950-8. 2008
    ..Overall, the photoplethysmogram provides a wealth of circulatory information, but its complex etiology may be a limitation in some novel applications...
  84. pmc Spatiotemporal dynamics of perfusion and oximetry during ictal discharges in the rat neocortex
    Mingrui Zhao
    Department of Neurological Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York 10021, USA
    J Neurosci 29:2814-23. 2009
    ..Possible mechanisms based on recent astrocyte-based models of neurovascular coupling are discussed...
  85. ncbi MR susceptometry for measuring global brain oxygen extraction
    Maria A Fernandez-Seara
    Center for Functional Neuroimaging, Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Magn Reson Med 55:967-73. 2006
    ..Unlike alternative methods, the susceptometric technique does not require calibration...
  86. ncbi Unexpected nocturnal hypoxia in patients with acute stroke
    Christine Roffe
    School of Medicine, Keele University, Staffordshire, UK
    Stroke 34:2641-5. 2003
    ..Sleep-related breathing disorders are common and may lead to episodes of nocturnal hypoxia even when daytime oxygenation is normal. The aim of this study was to assess the prevalence of unexpected nocturnal hypoxia in stroke patients...
  87. ncbi Automatic retinal oximetry
    Sveinn Hakon Hardarson
    Department of Ophthalmology, University of Iceland, National Univbersity Hospital, Reykjavik, Iceland
    Invest Ophthalmol Vis Sci 47:5011-6. 2006
    ..To measure hemoglobin oxygen saturation (SO(2)) in retinal vessels and to test the reproducibility and sensitivity of an automatic spectrophotometric oximeter...
  88. ncbi Precision of measurement of cerebral tissue oxygenation index using near-infrared spectroscopy in preterm neonates
    Line C Sorensen
    Department of Pediatrics, National University Hospital, Hvidovre, Copenhagen, Denmark
    J Biomed Opt 11:054005. 2006
    ..By measuring five times instead of one on each subject, the precision of the mean can be assumed to be comparable to pulse oximetry. This may be too cumbersome for clinical use, but may reduce sample size in research.
  89. ncbi Six-minute walk test for the evaluation of pulmonary disease severity in scleroderma patients
    Wander O Villalba
    Department of Physiotherapy, School of Medical Sciences, State University of Campinas, UNICAMP, Cidade Universitaria Zeferino Vuz, PO Box 6142, Campinas, Sao Paulo, Brazil
    Chest 131:217-22. 2007
    ....
  90. ncbi Retrospective correction for induced magnetic field inhomogeneity in measurements of large-vessel hemoglobin oxygen saturation by MR susceptometry
    Michael C Langham
    Laboratory for Structural NMR Imaging, Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Magn Reson Med 61:626-33. 2009
    MR susceptometry-based blood oximetry relies on phase mapping to measure the difference in magnetic susceptibility between intravascular blood and surrounding tissue...
  91. ncbi Achieved versus intended pulse oximeter saturation in infants born less than 28 weeks' gestation: the AVIOx study
    James I Hagadorn
    Division of Neonatology, Connecticut Children s Medical Center, 282 Washington St, Hartford, CT 06106, USA
    Pediatrics 118:1574-82. 2006
    ....
  92. ncbi Continuous monitoring of cerebral oxygen saturation in elderly patients undergoing major abdominal surgery minimizes brain exposure to potential hypoxia
    Andrea Casati
    Department of Anesthesiology, Azienda Ospedaliera di Parma, Via Gramsci 14, 43100 Parma, Italy
    Anesth Analg 101:740-7, table of contents. 2005
    ....
  93. ncbi Accuracy of pulse oximetry in the intensive care unit
    A Van de Louw
    Anesthesiology Department and Surgical Intensive Care Unit, Henri Mondor Hospital, , University Paris XII, , France
    Intensive Care Med 27:1606-13. 2001
    OBJECTIVE: Pulse oximetry (SpO2) is a standard monitoring device in intensive care units (ICUs), currently used to guide therapeutic interventions. Few studies have evaluated the accuracy of SpO2 in critically ill patients...
  94. pmc Quantitative evaluation of oxygenation in venous vessels using T2-Relaxation-Under-Spin-Tagging MRI
    Hanzhang Lu
    Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Magn Reson Med 60:357-63. 2008
    ..0 +/- 1.8%. Contrast agent infusion (Gd-DTPA, 0.1 mmol/kg) reduced venous blood T2 by 11.2 ms. The results of this study show that TRUST MRI is a useful technique for quantitative assessment of blood oxygenation in the brain...
  95. ncbi Estimation of oxygen saturation from erythrocytes by high-resolution spectroscopic optical coherence tomography
    Ji Yi
    Biomedical Engineering Department, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, USA
    Opt Lett 35:2094-6. 2010
    ..The result shows a reliable linear association between the SaO(2) derived from SOCT and the DS measurement, indicating this methodology has potential on in vivo applications to evaluate blood oxygenation...
  96. pmc Motion resistant pulse oximetry in neonates
    R Sahni
    Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Arch Dis Child Fetal Neonatal Ed 88:F505-8. 2003
    Pulse oximetry is widely used in neonates. However, its reliability is often affected by motion artefact...
  97. ncbi Nocturnal pulse oximetry as an abbreviated testing modality for pediatric obstructive sleep apnea
    R T Brouillette
    Department of Pediatrics, Montreal Children s Hospital, McGill University, Montreal, Canada
    Pediatrics 105:405-12. 2000
    To determine the utility of pulse oximetry for diagnosis of obstructive sleep apnea (OSA) in children.
  98. ncbi Planning adenotonsillectomy in children with obstructive sleep apnea: the role of overnight oximetry
    Gillian M Nixon
    Department of Pediatrics, McGill University and Montreal Children s Hospital, Montreal, Quebec, Canada
    Pediatrics 113:e19-25. 2004
    ..The objective of this study was to develop and validate a severity scoring system for overnight oximetry and to evaluate the score as a tool to prioritize the T&A surgical list.
  99. ncbi Portable optical tissue flow oximeter based on diffuse correlation spectroscopy
    Yu Shang
    Center for Biomedical Engineering, University of Kentucky, Lexington, Kentucky 40506, USA
    Opt Lett 34:3556-8. 2009
    ..9, P<10(-5), n=10). The portable, inexpensive, and easy-to-use DCS flow oximeter holds promise for bedside monitoring of tissue blood flow and oxygenation in clinics...
  100. ncbi Continuous pulse oximetry in acute hemiparetic stroke
    G Sulter
    Department of Neurology, Academisch Ziekenhuis Groningen, Postbus 30 001, 9700 RB, Groningen, The Netherlands
    J Neurol Sci 179:65-9. 2000
    ..The aim of this study was to assess the value of early continuous monitoring with pulse oximetry in detecting arterial oxygen desaturations in patients with acute hemiparetic stroke, and the effects of oxygen ..
  101. pmc Clinical assessment of infant colour at delivery
    Colm P F O'Donnell
    National Maternity Hospital, Holles Street, Dublin 2, Ireland
    Arch Dis Child Fetal Neonatal Ed 92:F465-7. 2007
    ..Use of video recordings of newborn infants to determine: (1) if clinicians agreed whether infants were pink; and (2) the pulse oximeter oxygen saturation (Spo(2)) at which infants first looked pink...

Research Grants63

  1. Iron-mediated vascular disease in sickle cell disease.
    John C Wood; Fiscal Year: 2010
    ..amp;citrulline, vitamin C, tetrahydrobiopterin, dihydrobiopterin,) and night time hypoxia (overnight pulse oximetry)...
  2. Hybrid Optical/Doppler Imaging of Ischemia in NEC - a multicenter trial
    David A Benaron; Fiscal Year: 2010
    ..tissue hypoxemia, which we have demonstrated to be detectable by combined broadband visible/near-infrared tissue oximetry, a real-time method that can assess the adequacy of deep tissue oxygenation...
  3. A Pilot Study of Yoga for Breathing and Quality of Life of Lung Cancer Patients
    JUDITH MARIE FOULADBAKHSH; Fiscal Year: 2013
    ..Outcome variables and related measures include: Breathing (spirometry, pulse oximetry, dyspnea, respiration rate, 6-Minute Walk test);oxygenation (pulse oximetry;heart rate);stress (Perceived Stress ..
  4. Hospital and Household Studies of Respiratory Cryptosporidiosis and Transmission
    Jeffrey K Griffiths; Fiscal Year: 2013
    ..The respiratory status of all children will be rigorously assessed, including pulse oximetry. Both groups will be screened for Cr...
  5. Validation in Baboon Model of Broadband NIR Monitoring for Neonate Gut Perfusion
    David A Benaron; Fiscal Year: 2012
    ..neonates relies on the traditional methods of monitoring such as arterial blood pressure, heart rate, pulse oximetry, urine output and evidence of metabolic acidosis...
  6. Eunice Kennedy Shriver NICHD Maternal Fetal Medicine Units Network
    Edward K Chien; Fiscal Year: 2013
    ..used in obstetric practice (ultrasound cervical length, fetal fibronectin, home uterine monitoring, fetal pulse oximetry)...
  7. 1st Tier Drugs+Theophylline in Pediatric Severe Asthma
    JERRY JOHN ZIMMERMAN; Fiscal Year: 2010
    ..appears to be associated with faster resolution of quantitative asthma scores, more rapid normalization of pulse oximetry saturation, and respiratory rate, and accelerated improvement in spirometry variables associated with small ..
  8. Modulated Imaging in Comprehensive Assessment of Diabetic Foot Ulcer Development
    Amaan Mazhar; Fiscal Year: 2012
    ..Tissue perfusion, oximetry, and hydration have been shown to predict ulcer healing and formation...
  9. Development of an instrument to track oxygen from blood to mitochondria in vivo
    Kenneth A Schenkman; Fiscal Year: 2013
    ..Evidenced by the explosion of new pulse oximetry and near infrared spectroscopy (NIRS) devices on the market, optical spectroscopy is attractive for noninvasive ..
  10. Perioperative Use and Outcomes of Noninvasive Ventilation in Sleep Apnea
    Peter K Lindenauer; Fiscal Year: 2013
    ..guidelines from the American Society of Anesthesiology recommend that all patients with OSA receive NIV and have oximetry monitoring for a prolonged period following surgery...
  11. MetaOx, Optical Monitor of Metabolic Rate of Oxygen Consumption
    BENIAMINO BARBIERI; Fiscal Year: 2013
    ..Conventional NIRS oximetry has failed to become a routine clinical tool in neonatology due to the poor sensitivity of SO2 in detecting brain ..
  12. Real-Time Flap Viability Monitoring during Facial Transplantation using SFDI
    BERNARD TRAVIS LEE; Fiscal Year: 2013
    ..The technology we propose to develop is analogous to pulse oximetry. But, rather than sample a single point of the body with NIR light, it provides a complete image of tissue ..
  13. Spatiotemporal Distribution of Oxygen in Biofilm Infections
    Philip S Stewart; Fiscal Year: 2013
    ..of oxygen distributions in novel in vitro biofilm models using microelectrodes and 19F magnetic resonance imaging oximetry. Specific aims of this project are to: 1) Derive integrated mathematical models for cystic fibrosis lung and ..
  14. Intelligent Sensor System for Early Illness Alerts in Senior Housing
    Marilyn J Rantz; Fiscal Year: 2013
    ..alerts for our intelligent sensor system (not telehealth that measures traditional vital signs, weight, pulse oximetry, blood sugar) and used it prospectively to measure functional ability in older adults and actually detected ..
  15. Intracellular oxygen sensing using 19F MRI
    Eric T Ahrens; Fiscal Year: 2013
    ..Towards these goals, we will explore the utility of real-time monitoring of intracellular oximetry in vivo using perfluorocarbon (PFC) emulsion imaging probes...
  16. Real-time Monitoring of cerebral tissue oxygen in ischemic stroke
    Nadeem Khan; Fiscal Year: 2013
    ..Our goal is to develop in vivo Electron Paramagnetic Resonance (EPR) oximetry with a novel class of implantable resonators for real-time monitoring of cerebral pO2 during ischemic stroke ..
  17. Surrogate measures of endothelial dysfunction with integrated MRI
    MICHAEL LANGHAM; Fiscal Year: 2013
    ..the time-course of blood oxygen resaturation in the femoral vein during hyperemia, referred to as "dynamic oximetry." A third technique, presently under development, allows rapid quantification of regional PWV from central to ..
  18. Direct and Indirect Protection by Influenza Vaccine Given to Children in India
    Wayne M Sullender; Fiscal Year: 2010
    ..Each FARI will be further characterized on the basis of clinical signs and symptoms, including pulse oximetry, and a respiratory specimen will be collected...
  19. Pulse Oximeter for Newborn Screening
    ROBERT A LIEBERMAN; Fiscal Year: 2013
    ..Using pulse oximetry (PO) can improve clinical examination by detecting CCHD that would otherwise be missed...
  20. Re-setting the Endothelial Ceramide Rheostat
    Richard N Kolesnick; Fiscal Year: 2013
    ..defects (measured by Dynamic MRI and Hoechst 33342 dye extravasation) and oxygen deprivation (measured by EPR oximetry), and that this vascular dysfunction represses DNA damage repair in tumor stem cells to enhance cure by SDRT...
  21. Cerebral Autoregulation Monitoring to Reduce Brain Injury from Cardiac Surgery
    OLA ARVID SELNES; Fiscal Year: 2013
    ..pressure and CBF velocity of the middle cerebral artery measured with transcranial Doppler and with cerebral oximetry measured with near infrared spectroscopy...
  22. Enhancing in vivo EPR imaging using spin probes with short relaxation times
    MARK TSEYTLIN; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Imaging of localized oxygen concentration (oximetry) and pH are key to the timing and sculpting of radiation treatment of tumors, improvement of wound healing, and design of therapy for peripheral ..
  23. MRI-Based Method for Quantifying CMRO2 in Humans
    Felix W Wehrli; Fiscal Year: 2012
    ..Other methods for quantifying CMRO2 rely on measuring venous oxygen saturation levels by jugular vein oximetry and flow via optical measurements or Doppler ultrasound...
  24. NIR Hypoxia Imaging of Breast Tumor Response to Neoadjuvant Chemotherapy in Vivo
    Shudong Jiang; Fiscal Year: 2010
    ..The overall goal of this proposal is to develop and evaluate dynamic NIR tomographic oximetry for characterizing the response of locally advanced breast cancers to neoadjuvant chemotherapy by assessing the ..
  25. Early Warning system for detecting pre-eclampsia
    Tammy Y Euliano; Fiscal Year: 2013
    ..The device employs a single ECG lead and a pulse oximetry probe. Software algorithms extract more than 80 features from these two technologies...
  26. Characterization of the Response to the Kappa Opiate Agonist Salvinorin A in Heal
    Mohini Ranganathan; Fiscal Year: 2012
    ..Physiological parameters (blood pressure, pulse rate, pulse oximetry) and pupil size will be measured. Blood will be sampled frequently for analysis of SA and plasma prolactin levels...
  27. Advanced Surgical Center for Translational Research at Dartmouth
    Thomas A Colacchio; Fiscal Year: 2010
    ..for surgical resection guidance, and (c) augment emerging research programs in prostate surgery, intraoperative oximetry imaging and in vivo optical microscopy...
  28. Improving Quality of Care for the Treatment of Childhood Pneumonia
    Patricia L Hibberd; Fiscal Year: 2012
    ..Investment in pulse oximetry to detect hypoxemia in rural and district hospitals worldwide has not occurred, partly because no clinical trial ..
  29. Randomized Clinical Trial of a Less-Invasive Resuscitation Protocol for Sepsis
    Alan E Jones; Fiscal Year: 2010
    ..mortality equivalence this fully invasive protocol to a less-invasive protocol by replacing central venous oximetry measurements with lactate clearance measurements...
  30. Biomarkers in Phototherapy of Barrett's Esophagus
    Kenneth K Wang; Fiscal Year: 2010
    ..using a novel reflectance probe that can assess tissue scattering and absorption coefficients as well as oximetry information...
  31. Integration of High Field MRI and EPRI For Functional Imaging
    JAY LOUIS ZWEIER; Fiscal Year: 2013
    ..structure, perfusion, energetic state and viability (MRI) with free radical distribution, redox state and oximetry (EPRI)...
  32. Pulse CO-Oximeter for Multiple Hemoglobin Species
    JONAS POLOGE; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Conventional pulse oximetry has significant limitations because it works on the assumption that there are only two species of hemoglobin present in arterial blood, oxygenated hemoglobin (O2Hb) and ..
  33. Neurological Emergencies Treatment Trials (NETT) Network Clinical Site Hubs
    Robert D Welch; Fiscal Year: 2013
    ..enrolled patient in the pre-hospital interventional trials Res-Q, PAD, PolyHeme, DCAR, POST and Cerebral oximetry trials...
  34. Hypoxia and Radiotherapy: Evaluation and Mitigation in Tumors
    Ralph P Mason; Fiscal Year: 2013
    ..growth delay following single high dose irradiation and pO2 in prostate tumors growing in rats based on 19F MR oximetry previously, but this required an exogenous reporter molecule...
  35. Sparse multispectral processing for accelerated EPR oximetry in three dimensions
    Lee C Potter; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: Electron paramagnetic resonance (EPR) oximetry provides a direct, minimally invasive measure of oxygen concentration...
  36. Non-intrusive Locomotion and Gait Stability Analysis Monitoring System for the El
    Sunil Saxena; Fiscal Year: 2007
    ..form-friendly, wireless, wrist-based device that provides the following functions: (1) Body Temperature (2) Pulse Oximetry (3) Heart Rate and (4) Location Information...
  37. A handheld scanner for clinical oximetry
    Periannan Kuppusamy; Fiscal Year: 2013
    ..Topical oximetry may also be useful for tracking peripheral vascular disease (PVD)...
  38. Detection of Intracellular Oxygen Species
    Sameh S Ali; Fiscal Year: 2011
    ..apply new lipophilic derivatives of the spin trap DEPMPO to trap O2-, 2) correlate EPR spectra and data from EPR oximetry to obtain information about the environment in which O2- is released, 3) characterize nanosensors based on ..
  39. SoundTrak: A Data Acquisition and Analysis System for OSDB
    B Parker; Fiscal Year: 2009
    ..Additionally, a commercial wireless wrist-worn finger oximetry system will be included in the Phase I study to investigate the issue of adequacy of ventilation during HFIS ..
  40. Surrogate markers for Severe Pulmonary Embolism
    JEFFREY KLINE; Fiscal Year: 2005
    ..8, a pulse oximetry reading >91 percent, a Daniel ECG score <8 points, and a troponin I <0...
  41. CEREBROVASCULAR RESERVE BY XE/CT VERSUS TCD AND OXIMETRY
    Ronda Pindzola; Fiscal Year: 2003
    ..Then Dr. Pindzola plans to design a study to assess risk for stroke in asymptomatic patients based on cerebrovascular reserve measurements. ..
  42. Venous Ulcers: Testing Effects of Compression & Position
    Deidre Wipke Tevis; Fiscal Year: 2005
    ..skin blood perfusion estimated by laser Doppler flux with skin blood perfusion estimated by transcutaneous oximetry with inspired 02 in the lower limbs of venous ulcer subjects and healthy adults in response to changes in leg/..
  43. Non-Intrusive Automated Portable Data Collection System for Aging Surveys
    Cindy Crump; Fiscal Year: 2009
    ..The scope of initial `mobile'data to be collected in real-time includes Pulse Oximetry, Heart Rate, Skin temperature, movement/gait analysis and a questionnaire...
  44. High resolution functional MRI of columnar structures
    Ravi Menon; Fiscal Year: 2007
    ..the major advantage that they still allow minimally invasive multi-modality measurements of electrophysiology, oximetry and flow...
  45. A Low Power Wireless Pulse Oximeter Sensor for Unobtrusive Wearable Applications
    PATRICK ALLAN LICHTER; Fiscal Year: 2011
    ..Recent studies with 24 hour pulse oximetry monitoring have demonstrated that the standard prescription does not properly oxygenate most patients...
  46. Spiral Electrode Sensor for Intrapartum Fetal Oximetry
    JONAS POLOGE; Fiscal Year: 2003
    ..Direct and continuous measurement of fetal oxygen saturation during labor requires the use of pulse oximetry, the continuous, noninvasive measurement of oxygen saturation in arterial blood...
  47. Heat Shock Proteins, Nitric Oxide and Oxygen Consumption in the Heart
    Govindasamy Ilangovan; Fiscal Year: 2009
    ..We propose to use electron paramagnetic resonance (EPR) oximetry with high sensitive LiPc microcrystals as probe and specially designed EPR instrumentation, to directly measure ..
  48. Spiral Electrode Sensor for Intrapartum Fetal Oximetry
    JONAS POLOGE; Fiscal Year: 2006
    ..This requires the use of pulse oximetry, the continuous, noninvasive measurement of oxygen saturation in arterial blood...
  49. Improved Spin Probes for Magnetic Resonance Imaging of Oxygen and Reactive Oxygen
    LAURA DUGAN; Fiscal Year: 2009
    ..are: 1) show that our N@C60 derivative has an EPR signal that is suitable for use as a spin probe for both oximetry and ROS detection, 2) compare N@C3 with currently available spin probes for both oximetry and detection of ..
  50. SCBA OXIMETRY FOR FIRE FIGHTER PHYSIOLOGIC MONITORING
    WILLIAM WIESMANN; Fiscal Year: 2005
    ..of personnel wearing personal protective equipment (PPE) through self-contained breathing apparatus (SCBA)-based oximetry systems, radio-telemetry and processing software for the development of an adjunct safety device addressing the ..
  51. CORRELATES OF PRETERM AND TERM INFANT FEEDING OUTCOMES
    Karen Pridham; Fiscal Year: 1992
    ..developed by Farrell and Palta and at each of the four study times with observation of respiratory effort, pulse oximetry, and maternal report of supplemental oxygen requirement...
  52. Near-infrared spectral imaging of the breast for cancer detection and monitoring
    Sergio Fantini; Fiscal Year: 2013
    ..tomographic reconstruction of hemoglobin/water/lipid/scattering-parameters distributions), quantitative oximetry, and temporal hemodynamics characterization...
  53. SCBA OXIMETRY FOR FIRE FIGHTER PHYSIOLOGIC MONITORING
    WILLIAM WIESMANN; Fiscal Year: 2000
    ..The proposed project focuses on remote physiologic status monitoring of personnel wearing PPE through SCBA-based oximetry systems, radio-telemetry and processing software...
  54. OXYGEN SATURATION MONITORING IN NEONATES
    SHYANG YUN SHIAO; Fiscal Year: 2001
    ..to validate bedside monitoring of SaO2, SvO2, and pulse oximetry (SpO2) by examining: a...
  55. Pulmonary Airflow Monitor in Tracheostomized Children
    MALVERN BENJAMIN; Fiscal Year: 2003
    ..Each of the current monitoring techniques, including capnography, pulse oximetry, or impedance pneumograpy has certain problems and limitations...
  56. STOP-ROP--A MULTICENTER TRIAL OF OXYGEN FOR ROP
    DALE PHELPS; Fiscal Year: 2001
    ..and randomly assigned oxygen administration at one of two specified oxygen levels, conventional (pulse oximetry of 89-94% saturation) vs supplemental (pulse oximetry of 96-99%)...
  57. A System for Management of Nasal CPAP Therapy
    LAUGHTON MILES; Fiscal Year: 2006
    ..The work will utilize a commercially available reflectance Pulse Oximetry Sensor modified to incorporate pressure control and be installed into the forehead support of existing ..
  58. MECHANICAL FACTORS AND ENERGY LOSS IN MYOCARDIAL REGIONS
    Joseph Kedem; Fiscal Year: 2001
    ..Local and global coronary blood flow will be measured, and regional O2 saturations as well as coronary sinus oximetry will be used to calculate regional and global MVO2 respectively...
  59. EVENT RECORDINGS OF HIGH RISK INFANTS ON APNEA MONITORS
    DEBRA WEESE MAYER; Fiscal Year: 1991
    ..Event recording with TTI/ECG and pulse oximetry will be initiated on admission to the study and continued for 6 months...
  60. An Electrical Impedance Monitor
    Justin Clark; Fiscal Year: 2004
    ..This principle has been used successfully to measure hematocrit in vitro and in pulse oximetry. The method should be ideal as a screening tool for prospective blood donors as well as for applications in ..
  61. Development of a Universal Calibration Method for a Noninvasive Glucometer
    ROBERT PEURA; Fiscal Year: 2009
    ..will allow the user to employ our noninvasive glucometer without a pre-use calibration session, similar to pulse oximetry. Currently, we use a partial least squares regression to develop individual models for each subject...
  62. PSYCHOPHYSIOLOGY AND FAMILY IN CHILDHOOD ASTHMA
    Beatrice Wood; Fiscal Year: 2000
    ..The patient's pulmonary function will also be monitored during the FPSS via pulse oximetry and spirometry, non-invasive measures of airways obstruction...
  63. FREQUENCY DOMAIN CEREBRAL OXIMETER FOR PEDIATRICS
    DEAN KURTH; Fiscal Year: 2003
    ..Near infrared spectroscopy (cerebral oximetry) is an emerging optical technology with the potential to fulfill this role...