Genomes and Genes
Summary: The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
Publications404 found, 100 shown here
- Cardiac output monitoringEric E C de Waal
Division of Perioperative and Emergency Care, University Medical Centre Utrecht, Utrecht, The Netherlands
Curr Opin Anaesthesiol 22:71-7. 2009..The most ideal cardiac output (CO) monitor should be reliable, continuous, noninvasive, operator-independent and cost-effective and should ..
- Run sprint interval training improves aerobic performance but not maximal cardiac outputRebecca E K Macpherson
Exercise Nutrition Research Laboratory, Faculty of Health Sciences, School of Kinesiology, The University of Western Ontario, London, Canada
Med Sci Sports Exerc 43:115-22. 2011..However, most SIT data use cycling, and little is known about its effects on body composition or maximal cardiac output (Qmax).
- Decreased cardiac output, venous congestion and the association with renal impairment in patients with cardiac dysfunctionKevin Damman
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Eur J Heart Fail 9:872-8. 2007Renal failure in heart failure is related to decreased cardiac output. However, little is known about its association with venous congestion.
- The respiratory variation in inferior vena cava diameter as a guide to fluid therapyMarc Feissel
Réanimation Médicale et Maladies Infectieuses, Centre Hospitalier de Belfort, Belfort, France
Intensive Care Med 30:1834-7. 2004..To investigate whether the respiratory variation in inferior vena cava diameter (DeltaD(IVC)) could be related to fluid responsiveness in mechanically ventilated patients...
- Equivalence of the bioimpedance and thermodilution methods in measuring cardiac output in hospitalized patients with advanced, decompensated chronic heart failureNancy M Albert
Division of Nursing, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Am J Crit Care 13:469-79. 2004An accurate and reliable noninvasive method for determining cardiac output/cardiac index would be valuable for patients with acutely decompensated advanced systolic heart failure.
- Accuracy and repeatability of pediatric cardiac output measurement using Doppler: 20-year review of the literatureMichelle S Chew
Department of Anesthesia and Intensive Care, Lund University Hospital, 22185, Lund, Sweden
Intensive Care Med 29:1889-94. 2003Review of the accuracy and repeatability of Doppler cardiac output (CO) measurements in children.
- Respiratory changes in aortic blood velocity as an indicator of fluid responsiveness in ventilated patients with septic shockM Feissel
, Centre Hospitalier, Belfort, France
Chest 119:867-73. 2001....
- Systolic pressure variation as a guide to fluid therapy in patients with sepsis-induced hypotensionB Tavernier
Department of Anesthesia 2, University Hospital, Lille, France
Anesthesiology 89:1313-21. 1998..maximal and minimal systolic blood pressure values during one mechanical breath), and its delta down (dDown) component (= apneic - minimum systolic blood pressure) with the response of cardiac output to volume expansion during sepsis.
- Balance between cardiac output and sympathetic nerve activity in resting humans: role in arterial pressure regulationN Charkoudian
Department of Physiology and Biomedical Engineering, JO 4184W, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
J Physiol 568:315-21. 2005..We studied the relationship between cardiac output (CO) and baroreflex control of sympathetic activity by measuring MSNA (peroneal microneurography), arterial ..
- A critical review of the ability of continuous cardiac output monitors to measure trends in cardiac outputLester A Critchley
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China
Anesth Analg 111:1180-92. 2010Numerous cardiac output (CO) monitors have been produced that provide continuous rather than intermittent readings. Bland and Altman has become the standard method for validating their performance against older standards...
- Noninvasive cardiac output monitoring (NICOM): a clinical validationPierre Squara
CERIC, Clinique Ambroise Pare, 27, boulevard Victor Hugo, 92200, Neuilly sur Seine, France
Intensive Care Med 33:1191-4. 2007To evaluate the clinical utility of a new device for continuous noninvasive cardiac output monitoring (NICOM) based on chest bio-reactance compared with cardiac output measured semi-continuously by thermodilution using a pulmonary artery ..
- Cardiac output monitoring using indicator-dilution techniques: basics, limits, and perspectivesDaniel A Reuter
Department of Anesthesiology, Hamburg Eppendorf University Hospital, Martinistr 52, 20246 Hamburg, Germany
Anesth Analg 110:799-811. 2010The ability to monitor cardiac output is one of the important cornerstones of hemodynamic assessment for managing critically ill patients at increased risk for developing cardiac complications, and in particular in patients with ..
- Flow measurement by cardiovascular magnetic resonance: a multi-centre multi-vendor study of background phase offset errors that can compromise the accuracy of derived regurgitant or shunt flow measurementsPeter D Gatehouse
CMR Unit, Royal Brompton Hospital, London, UK
J Cardiovasc Magn Reson 12:5. 2010..We studied the severity of uncorrected velocity offset errors across sites and CMR systems...
- Reduced cardiac output in imported Plasmodium falciparum malariaJohanna Herr
University Medical Center Hamburg Eppendorf, Section Tropical Medicine, Bernhard Nocht Strasse 74, 20359 Hamburg, Germany
Malar J 10:160. 2011..In the present study, cardiac function and cardiac proteins have been assessed and correlated with parasitological and immunologic parameters in patients with imported Plasmodium falciparum malaria...
- Comparison of noninvasive cardiac output measurements using the Nexfin monitoring device and the esophageal DopplerGuo Chen
Department of Anesthesiology and Perioperative Care, University of California, Irvine, CA 92868, USA
J Clin Anesth 24:275-83. 2012To evaluate the validity of cardiac output (CO) measurements obtained using the Nexfin device in comparison to those obtained with the esophageal Doppler in steady-state conditions and after phenylephrine administration.
- The Fontan circulation: who controls cardiac output?Marc Gewillig
Paediatric and Congenital Cardiology, University Hospitals Leuven, Belgium
Interact Cardiovasc Thorac Surg 10:428-33. 2010In a Fontan circuit the mechanisms involved in control of cardiac output at rest and during exercise differ significantly from normal. The classical model presumes an unlimited preload which is not available in the Fontan circuit...
- Cardiac output and cardiac index measured with cardiovascular magnetic resonance in healthy subjects, elite athletes and patients with congestive heart failureMarcus Carlsson
Department of Clinical Physiology and Nuclear Medicine, BFC, Skane University Hospital, Lund University, Lund, SE 22185, Sweden
J Cardiovasc Magn Reson 14:51. 2012Cardiovascular Magnetic Resonance (CMR) enables non-invasive quantification of cardiac output (CO) and thereby cardiac index (CI, CO indexed to body surface area)...
- Separating the direct effect of hypoxia from the indirect effect of changes in cardiac output on the maximum pressure difference across the tricuspid valve in healthy humansGeorge M Balanos
School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
Pflugers Arch 450:372-80. 2005In healthy humans, changes in cardiac output are commonly accommodated with minimal change in pulmonary artery pressure. Conversely, exposure to hypoxia is associated with substantial increases in pulmonary artery pressure...
- A comparison of the Nexfin® and transcardiopulmonary thermodilution to estimate cardiac output during coronary artery surgeryO Broch
Department of Anaesthesiology and Intensive Care Medicine, Christian Albrechts University, Kiel, Germany
Anaesthesia 67:377-83. 2012..We compared the cardiac output derived from the Nexfin and PiCCO, using transcardiopulmonary thermodilution, during cardiac surgery...
- Comparison of uncalibrated arterial pressure waveform analysis with continuous thermodilution cardiac output measurements in patients undergoing elective off-pump coronary artery bypass surgeryYong Bo Jeong
Department of Anesthesiology and Pain Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea
J Cardiothorac Vasc Anesth 24:767-71. 2010Monitoring of cardiac output is required during anesthesia for off-pump coronary artery bypass (OPCAB) surgery...
- Hemodynamic and perfusion end points for volemic resuscitation in sepsisFernando José da Silva Ramos
Intensive Care and Anesthesiology Research Laboratory, Research and Education Institute, Hospital Sirio Libanes, University of Sao Paulo School of Medicine, Sao Paulo, Brazil
Shock 34:34-9. 2010....
- Reliability of a new ultrasonic cardiac output monitor in recipients of living donor liver transplantationBai Chuan Su
Department of Anesthesia, Chang Gung Memorial Hospital Linkou, Kwei Shan, Taoyuan, Taiwan, Republic of China
Liver Transpl 14:1029-37. 2008The ultrasonic cardiac output monitor (USCOM) is a new Doppler device for noninvasive hemodynamic monitoring...
- Performance of cardiac output measurement derived from arterial pressure waveform analysis in patients requiring high-dose vasopressor therapyS Metzelder
Department of Anaesthesiology, University Hospital of the RWTH Aachen, Pauwelsstr 30, D 52074 Aachen, Germany
Br J Anaesth 106:776-84. 2011Arterial pressure waveform analysis of cardiac output (APCO) without external calibration (FloTrac/Vigileo™) is critically dependent upon computation of vascular tone that has necessitated several refinements of the underlying software ..
- Central venous pressure measurements improve the accuracy of leg raising-induced change in pulse pressure to predict fluid responsivenessKarim Lakhal
Service de Réanimation Médicale et Maladies Infectieuses, Hopital Bichat Claude Bernard, Assistance Publique des Hopitaux de Paris, Paris, France
Intensive Care Med 36:940-8. 2010..We assessed the influence of PLR-induced changes in preload on the performance of PLR-induced change in pulse pressure (Delta(PLR)PP) and cardiac output (Delta(PLR)CO) for fluid responsiveness prediction.
- Circulatory responses to a meal in patients with a newly transplanted heartB A Waaler
Department of Physiology, Institute of Basic Medical Sciences, University of Oslo, Post Box 1103, Blindern, 0317 Oslo, Norway
Acta Physiol Scand 174:101-8. 2002..quite marked increase in blood flow to the gastrointestinal organs and a similar and simultaneous increase in cardiac output (CO)...
- Fluid resuscitation preserves cardiac output but cannot prevent organ damage in a porcine model during 24 h of intraabdominal hypertensionAlexander Schachtrupp
Department of Surgery, Technical University of Aachen, Aachen, Germany
Shock 24:153-8. 2005According to a previous study, a pathologically increased intraabdominal pressure (IAP) reduces cardiac output (CO) and results in medium- to high-grade organ damage in a porcine model of the abdominal compartment syndrome (ACS)...
- Prediction of fluid responsiveness in acute respiratory distress syndrome patients ventilated with low tidal volume and high positive end-expiratory pressureChung Chi Huang
Division of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital, Gweishan, Taoyuan, Taiwan
Crit Care Med 36:2810-6. 2008....
- Continuous cardiac output and near-infrared spectroscopy monitoring to assist in management of symptomatic cerebral vasospasm after subarachnoid hemorrhageTatsushi Mutoh
Department of Surgical Neurology, Research Institute for Brain and Blood Vessels Akita, 6 10 Senshu Kubota machi, Akita, 010 0874, Japan
Neurocrit Care 13:331-8. 2010Hemodynamic augmentation by increasing cardiac output with dobutamine (DOB) is believed to be a useful method of elevating decreased cerebral blood flow in the territory affected by vasospasm following aneurysmal subarachnoid hemorrhage (..
- Cardiac output as a potential risk factor for abnormal brain agingAngela L Jefferson
Department of Neurology, Alzheimer s Disease Center, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA 02118, USA
J Alzheimers Dis 20:813-21. 2010..data suggesting that subtle cardiac dysfunction or low normal levels of cardiac function, as quantified by cardiac output, are related to cognitive and neuroimaging markers of abnormal brain aging in the absence of heart failure or ..
- Assessment of intrathoracic blood volume as an indicator of cardiac preload: single transpulmonary thermodilution technique versus assessment of pressure preload parameters derived from a pulmonary artery catheterC Wiesenack
Department of Anaesthesia, University Hospital, Regensburg, Germany
J Cardiothorac Vasc Anesth 15:584-8. 2001OBJECTIVE: To analyze the clinical value of a new device (PiCCO) for cardiac output measurement and volume preload parameter assessment, based on transpulmonary thermodilution technique, as an alternative to the pulmonary artery ..
- Evaluation of a noninvasive continuous cardiac output monitoring system based on thoracic bioreactanceHanan Keren
Cheetah Medical Limited, Ra anana, Israel
Am J Physiol Heart Circ Physiol 293:H583-9. 2007Noninvasive cardiac output (CO) measurement can be useful in many clinical settings where invasive monitoring is not desired...
- Tracking changes in cardiac output: methodological considerations for the validation of monitoring devicesPierre Squara
Réanimation CERIC, Clinique Ambroise Pare, 27, boulevard Victor Hugo, 92200, Neuilly, France
Intensive Care Med 35:1801-8. 2009Until now, tools for continuous cardiac output (CO) monitoring have been validated as if they were tools for snapshot measurements...
- The validity of trans-esophageal Doppler ultrasonography as a measure of cardiac output in critically ill adultsPaul M Dark
Department of Intensive Care Medicine, Injury, Repair and Rehabilitation Research Group, Hope Hospital, University of Manchester, Stott Lane, M6 8HD, Greater Manchester, UK
Intensive Care Med 30:2060-6. 2004To determine the validity of the esophageal Doppler monitor (EDM) and echo-esophageal Doppler (Echo-ED) in measuring cardiac output in the critically ill.
- Flow measurement by magnetic resonance: a unique asset worth optimisingPhilip J Kilner
CMR Unit, Royal Brompton Hospital, Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, Sydney Street, London, UK
J Cardiovasc Magn Reson 9:723-8. 2007..through planes transecting the great arteries should provide the most accurate measurements available of cardiac output, shunt flow, aortic or pulmonary regurgitation and, indirectly, of mitral regurgitation...
- Clinical review: Positive end-expiratory pressure and cardiac outputThomas Luecke
Department of Anesthesiology and Critical Care Medicine, University Hospital of Mannheim, Germany
Crit Care 9:607-21. 2005..As heart rate usually does not change with PEEP, the entire fall in cardiac output is a consequence of a reduction in left ventricular stroke volume (SV)...
- Non-invasive beat-to-beat cardiac output monitoring by an improved method of transthoracic bioimpedance measurementJ Fortin
Institute of Medical Engineering, Graz University of Technology, Krenngasse 37, A 8010 Graz, Austria
Comput Biol Med 36:1185-203. 2006..Examples of stroke volume and cardiac output curves underline the capabilities of the monitoring system "Task Force Monitor"...
- A meta-analysis of studies using bias and precision statistics to compare cardiac output measurement techniquesL A Critchley
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
J Clin Monit Comput 15:85-91. 1999Bias and precision statistics have succeeded regression analysis when measurement techniques are compared. However, when applied to cardiac output measurements, inconsistencies occur in reporting the results of this form of analysis.
- Cardiac output estimation with a new Doppler device after off-pump coronary artery bypass surgeryRajesh Chand
Department of Anesthesiology and Critical Care, Escorts Heart Institute and Research Centre, New Delhi, India
J Cardiothorac Vasc Anesth 20:315-9. 2006To compare cardiac output (CO), stroke volume (SV), and cardiac index (CI) as estimated with a new, noninvasive Doppler device (Ultrasonic Cardiac Output Monitor [USCOM]; USCOM Ltd, Sydney, Australia) with those measured with the bolus ..
- Effects of changes in vascular tone on the agreement between pulse contour and transpulmonary thermodilution cardiac output measurements within an up to 6-hour calibration-free periodOlfa Hamzaoui
Service de Reanimation Medicale, Centre Hospitalo Universitaire de Bicêtre, Assistance Publique Hopitaux de Paris, EA 4046, Université Paris 11, Le Kremlin Bicetre, France
Crit Care Med 36:434-40. 2008..To examine whether the agreement between pulse contour and transpulmonary thermodilution cardiac index (CI) measurements is altered by changes in vascular tone within an up to 6-hr calibration-free period...
- Echocardiographic measurement of fluid responsivenessCyril Charron
Medical Intensive Care Unit, University Hospital Ambroise Pare, Assistance Publique Hopitaux de Paris, Boulogne, France
Curr Opin Crit Care 12:249-54. 2006..In the last few years, several French teams have used echocardiography to develop new parameters of fluid responsiveness, taking advantage of its ability to monitor cardiac function beat by beat during the respiratory cycle...
- Minimal haemodynamic system model including ventricular interaction and valve dynamicsBram W Smith
Department of Mechanical Engineering, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
Med Eng Phys 26:131-9. 2004..Examples of results include a 9% drop in cardiac output when increasing the thoracic pressure from -4 to 0 mmHg, and an increase in blood pressure from 120/80 to 165/..
- Determinants of maximal oxygen uptake in moderate acute hypoxia in endurance athletesPascal Mollard
Laboratoire Réponses Cellulaires et Fonctionnelles à l Hypoxie, Universite Paris 13, 74 rue Marcel Cachin, EA2363, ARPE, 93017 Bobigny Cedex, France
Eur J Appl Physiol 100:663-73. 2007..Heart rate (HR), stroke volume (SV), cardiac output (.Q), arterialized oxygen saturation (Sa'O2), oxygen uptake (.VO2max), ventilation (...
- Cardiac output and central distribution of blood flow in the human fetusG Mielke
Department of Obstetrics and Gynecology, University of Tuebingen, Tuebingen, Germany
Circulation 103:1662-8. 2001The objectives of this study were to establish reference ranges for left and right cardiac output and to investigate blood flow distribution through the foramen ovale, ductus arteriosus, and pulmonary bed in human fetuses.
- Fetal cardiac output, distribution to the placenta and impact of placental compromiseT Kiserud
Department of Clinical Medicine, Section of Obstetrics and Gynaecology, University of Bergen, Bergen, Norway
Ultrasound Obstet Gynecol 28:126-36. 2006..Our aim was to determine the normal distribution of fetal cardiac output to the placenta during the second half of pregnancy, and to assess the changes imposed by growth restriction ..
- Beta-adrenergic or parasympathetic inhibition, heart rate and cardiac output during normoxic and acute hypoxic exercise in humansSusan R Hopkins
Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA
J Physiol 550:605-16. 2003Acute hypoxia increases heart rate (HR) and cardiac output (Qt) at a given oxygen consumption (VO2) during submaximal exercise...
- Monitoring cardiac function in intensive careS M Tibby
Department of Paediatric Intensive Care, Guy s Hospital, London SE1 9RT, UK
Arch Dis Child 88:46-52. 2003..afterload is difficult; thus in clinical practice the bedside assessment of cardiac function is represented by cardiac output. A variety of techniques are now available for cardiac output measurement in the paediatric patient...
- Noninvasive, automated and continuous cardiac output monitoring by pulmonary capnodynamics: breath-by-breath comparison with ultrasonic flow probePhilip J Peyton
Department of Anesthesia, Austin Hospital, Heidelberg, Victoria, Australia
Anesthesiology 105:72-80. 2006b>Cardiac output monitoring is most important where cardiovascular stability is potentially threatened, such as during major surgery and in critically ill patients...
- Reduced cardiac output is associated with decreased mitochondrial efficiency in the non-ischemic ventricular wall of the acute myocardial-infarcted dogZakaria A Almsherqi
Department of Physiology, National University of Singapore, Block MD9, 2 Medical Drive, Singapore 117597, Singapore
Cell Res 16:297-305. 2006..Hemodynamic measurements revealed a > 50% reduction in cardiac output at 24 h post infarction when compared to baseline...
- Volume-limited versus pressure-limited hemodynamic management in septic and nonseptic shockRonald J Trof
Department of Intensive Care, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
Crit Care Med 40:1177-85. 2012..To evaluate the effect of hemodynamic management guided by upper limits of cardiac filling volumes or pressures on durations of mechanical ventilation and lengths of stay in critically ill patients with shock...
- Third-generation FloTrac/Vigileo does not reliably track changes in cardiac output induced by norepinephrine in critically ill patientsX Monnet
Hôpitaux Universitaires Paris Sud, Hopital de Bicetre, Service de Reanimation Medicale, 78, rue du General Leclerc, Le Kremlin Bicêtre F 94270, France
Br J Anaesth 108:615-22. 2012..The ability of the third-generation FloTrac/Vigileo software to track changes in cardiac index (CI) induced by volume expansion and norepinephrine in critically ill patients is unknown...
- Discrepancy between cardiac and physical functional reserves in strokeDjordje G Jakovljevic
Newcastle University, Newcastle upon Tyne, NE2 4HH, UK
Stroke 43:1422-5. 2012..This study defines (1) whether exercise capacity is limited by the cardiovascular system (oxygen supply) or skeletal muscles (oxygen utilization); and (2) cardiac function and pumping capability in people with stroke...
- Cardiopulmonary effects of low-dose arginine vasopressin in ovine acute lung injuryMartin Westphal
Department of Anesthesiology, The University of Texas Medical Branch, Galveston, TX, USA
Crit Care Med 39:357-63. 2011..To elucidate the effects of low-dose arginine vasopressin on cardiopulmonary functions and nitrosative stress using an established model of acute lung injury...
- Hemodynamics among neonates with hypoxic-ischemic encephalopathy during whole-body hypothermia and passive rewarmingCorinna Mirjam Gebauer
Department of Neonatology, Children s Hospital, University of Leipzig, Leipzig, Germany
Pediatrics 117:843-50. 2006..To assess changes in cardiac performance, with Doppler echocardiography, among newborns with hypoxic-ischemic encephalopathy during mild therapeutic hypothermia and during rewarming...
- Proteins within the intracellular calcium store determine cardiac RyR channel activity and cardiac outputAngela F Dulhunty
Department of Translational Biosciences, John Curtin School of Medical Research, Australian National University, Canberra, Australian Capital Territory, Australia
Clin Exp Pharmacol Physiol 39:477-84. 2012..Herein, we discuss known interactions between the RyR, triadin, junctin and CSQ with emphasis on the cardiac isoforms of the proteins. Where there is little known about the cardiac isoforms, we discuss evidence from skeletal isoforms...
- Arterial pressure allows monitoring the changes in cardiac output induced by volume expansion but not by norepinephrineXavier Monnet
Service de Reanimation Medicale, Hopital de Bicetre, AP HP, Le Kremlin Bicetre, France
Crit Care Med 39:1394-9. 2011To evaluate to which extent the systemic arterial pulse pressure could be used as a surrogate of cardiac output for assessing the effects of a fluid challenge and of norepinephrine.
- A new impedance cardiograph device for the non-invasive evaluation of cardiac output at rest and during exercise: comparison with the "direct" Fick methodA Charloux
Service des Explorations Fonctionnelles Respiratoires, Cardio Circulatoires et de l Exercise, Hopitaux Universitaires de Strasbourg, Hopital Civil, France
Eur J Appl Physiol 82:313-20. 2000..We compared cardiac output determined simultaneously by two methods, the Physio Flow (QcPF) and the direct Fick (QcFick) methods...
- Reliability of peak VO(2) and maximal cardiac output assessed using thoracic bioimpedance in childrenJoanne Welsman
Children s Health and Exercise Research Centre, University of Exeter, Heavitree Road, Exeter, EX1 2LU, UK
Eur J Appl Physiol 94:228-34. 2005..the reliability of a thoracic electrical bioimpedance based device (PhysioFlow) for the determination of cardiac output and stroke volume during exercise at peak oxygen uptake (peak VO(2) in children...
- Effects of ventilation on cardiac output determined by inert gas rebreathingMorten Damgaard
Medical Department B, Department of Aviation Medicine, Copenhagen University Hospital, Denmark
Clin Physiol Funct Imaging 25:142-7. 2005..Therefore, in 10 healthy males we investigated the effects of changes in ventilation pattern on cardiac output (CO) estimated by an N(2)O-rebreathing technique. Reducing the rebreathing volume (V(reb)) from 1.5 to 1...
- The relationship between the photoplethysmographic waveform and systemic vascular resistanceAymen A Awad
Department of Anesthesiology, Yale University School of Medicine, 333 Cedar Street, P O Box 208051, New Haven, CT 06520 8051, USA
J Clin Monit Comput 21:365-72. 2007..The objective of this study was to determine the relationship between systemic vascular resistance (SVR), finger & ear photoplethysmographic measurements in 14 adult patients undergoing coronary artery bypass grafting (CABG)...
- A new non-invasive continuous cardiac output trend solely utilizing routine cardiovascular monitorsHironori Ishihara
Department of Anesthesiology, University of Hirosaki School of Medicine, Hirosaki, Japan
J Clin Monit Comput 18:313-20. 2004Three of the us developed a new non-invasive continuous cardiac output (CCO) measurement method utilizing routine clinical monitors based on the pulse-contour analysis combined with pulse wave transit time (PWTT)...
- Cardiac output and sympathetic vasoconstrictor responses during upright tilt to presyncope in healthy humansQi Fu
Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, TX 75231, USA
J Physiol 590:1839-48. 2012..The purpose of this study was to determine the role of cardiac output and sympathetic vasoconstriction in neurally mediated (pre)syncope...
- Cardiac output determination from endotracheally measured impedance cardiography: clinical evaluation of endotracheal cardiac output monitorTimothy M Maus
Thornton Hospital, University of California San Diego, La Jolla, CA 92093 7770, USA
J Cardiothorac Vasc Anesth 25:770-5. 2011To evaluate the accuracy, precision, and trending of a new endotracheally sourced impedance cardiography-based cardiac output (CO) monitor (ECOM; ConMed Corp, Irvine, CA).
- Clonidine lowers blood pressure by reducing vascular resistance and cardiac output in young, healthy malesAnna Mitchell
Department of Nephrology, University of Essen, Hufelandstrasse 55, 45122, Essen, Germany
Cardiovasc Drugs Ther 19:49-55. 2005..study was to determine the hemodynamic response to Clonidine under physiological conditions and to test the hypothesis that Clonidine would reduce cardiac output and blood pressure resulting in an increase in total peripheral resistance.
- Post-prandial blood flow to the gastrointestinal tract is not compromised during hypoxia in the sea bass Dicentrarchus labraxMichael Axelsson
Department of Zoology, University of Goteborg, Sweden
J Exp Biol 205:2891-6. 2002..blood flow will be reduced during hypoxia to prioritise blood flow to other organs was tested by measuring cardiac output and gut blood flow during a stepwise hypoxic challenge (five steps, from 20.6 to 3...
- Temporary biventricular pacing postcardiopulmonary bypass in patients with reduced ejection fractionJochen D Muehlschlegel
Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Card Surg 23:324-30. 2008..This study analyzed the response of BiV versus single ventricle lead pacing on hemodynamics and left ventricular (LV) function immediately following CPB...
- Comparison of the USCOM ultrasound cardiac output monitor with pulmonary artery catheter thermodilution in patients undergoing liver transplantationLai Sze Grace Wong
Department of Anaesthesiology, Queen Mary Hospital, Hong Kong
Liver Transpl 14:1038-43. 2008The aim of the study was to compare the standard technique of cardiac output determination by pulmonary artery catheter thermodilution (PAC-TD) with a noninvasive ultrasound Doppler monitor (USCOM Pty., Ltd...
- Finapres arterial pulse wave analysis with Modelflow is not a reliable non-invasive method for assessment of cardiac outputJaap J Remmen
Department of Geriatric Medicine, Heartcenter, Department of Cardiology, University Medical Center Nijmegen, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Clin Sci (Lond) 103:143-9. 2002Non-invasive continuous monitoring of cardiac output could be very useful in clinical care and in research settings, particularly in elderly subjects...
- A critical comparison of echocardiographic measurements used for optimizing cardiac resynchronization therapy: stroke distance is bestDewi E Thomas
Wales Heart Research Institute, School of Medicine, Cardiff University, Heath Park, Cardiff, UK
Eur J Heart Fail 11:779-88. 2009..We also assessed the utility of 'stroke distance' [left ventricular outflow tract velocity-time integral (LVOT VTI)] in performing this function...
- Understanding the contribution of Guyton's large circulatory model to long-term control of arterial pressureJean Pierre Montani
Department of Medicine, Division of Physiology, University of Fribourg, Rue du Musee 5, CH 1700 Fribourg, Switzerland
Exp Physiol 94:382-8. 2009..of circulatory control, Guyton and colleagues challenged the then prevailing views on how blood pressure and cardiac output were controlled...
- Bevacizumab in patients with hereditary hemorrhagic telangiectasia and severe hepatic vascular malformations and high cardiac outputSophie Dupuis-Girod
Hospices Civils de Lyon, Hopital Louis Pradel, Genetic Department and National Reference Center for Rendu Osler Disease, Bron, France
JAMA 307:948-55. 2012The only treatment available to restore normal cardiac output in patients with hereditary hemorrhagic telangiectasia (HHT) and cardiac failure is liver transplant...
- End-tidal CO2 pressure decreases during exercise in cardiac patients: association with severity of heart failure and cardiac output reserveA Matsumoto
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan
J Am Coll Cardiol 36:242-9. 2000We measured end-tidal CO2 pressure (PETCO2) during exercise and investigated the relationship between PETCO2 and exercise capacity, ventilatory parameters and cardiac output to determine the mechanism(s) of changes in this parameter.
- Acute biventricular pacing after cardiac surgery has no influence on regional and global left ventricular systolic functionChristoph Schmidt
Department of Cardiology, Triemli Hospital, Birmensdorferstr 497, 8063 Zurich, Switzerland
Europace 9:432-6. 2007..determined by tissue Doppler imaging (TDI) and global LV systolic function determined by the continuous cardiac output method were measured during various pacing configurations in patients with depressed LV systolic function ..
- Relationship between aortic-to-radial arterial pressure gradient after cardiopulmonary bypass and changes in arterial elasticityMasahiro Kanazawa
Department of Anesthesiology, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa, Japan
Anesthesiology 99:48-53. 2003..To clarify the cause of the pressure gradient after CPB, the authors investigated the relationship between the pressure gradient and changes in the pulse wave velocity (PWV) before and after CPB...
- Cardiac output measurement in children: comparison of the Ultrasound Cardiac Output Monitor with thermodilution cardiac output measurementWalter Knirsch
Division of Pediatric Cardiology, University Children s Hospital, Steinwiesstrasse 75, Zurich, Switzerland
Intensive Care Med 34:1060-4. 2008To compare the assessment of cardiac output (CO) in children using the noninvasive Ultrasound Cardiac Output Monitor (USCOM) with the invasive pulmonary artery catheter (PAC) thermodilution cardiac output measurement.
- Feasibility of cardiac output estimation by ultrasonic cardiac output monitoring in the prehospital settingFrancois Xavier Duchateau
Department of Anaesthesiology and Intensive Care, Beaujon University Hospital, Clichy, France
Eur J Emerg Med 18:357-9. 2011The possible benefits of ultrasonic cardiac output monitoring (USCOM) in emergency medicine practice could be significant if evaluated in a goal-directed protocol...
- Global end-diastolic volume during different loading conditions in a pediatric animal modelJochen Renner
Department of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig Holstein, Kiel, Germany
Anesth Analg 105:1243-9, table of contents. 2007..Therefore, we designed the present study to evaluate whether GEDV and PPV are suitable variables of preload and fluid responsiveness during rapidly changing loading conditions in a pediatric animal model...
- Minimally invasive measurement of cardiac output during surgery and critical care: a meta-analysis of accuracy and precisionPhilip J Peyton
Department of Anaesthesia, Austin Hospital, Melbourne, Australia
Anesthesiology 113:1220-35. 2010When assessing the accuracy and precision of a new technique for cardiac output measurement, the commonly quoted criterion for acceptability of agreement with a reference standard is that the percentage error (95% limits of agreement/mean ..
- Dynamic preload indicators fail to predict fluid responsiveness in open-chest conditionsEric E C de Waal
Division of Perioperative and Emergency Care, University Medical Center, Utrecht, The Netherlands
Crit Care Med 37:510-5. 2009..However, in open-chest conditions, the value of these indices has not been systematically examined yet. We, therefore, evaluated the ability of PPV and SVV to predict fluid responsiveness under open- and closed-chest conditions...
- Heart stroke volume, cardiac output, and ejection fraction in 265 normal fetus in the second half of gestation assessed by 4D ultrasound using spatio-temporal image correlationChristiane Simioni
Department of Obstetrics, Sao Paulo Federal University UNIFESP, Sao Paulo, Brazil
J Matern Fetal Neonatal Med 24:1159-67. 2011The aim of this study was to establish nomograms for fetal stroke volume (SV), cardiac output (CO), and ejection fraction (EF) using four-dimensional ultrasound with spatio-temporal image correlation (STIC) modality.
- Assessing the diagnostic accuracy of pulse pressure variations for the prediction of fluid responsiveness: a "gray zone" approachMaxime Cannesson
Department of Anesthesiology and Perioperative Care, School of Medicine, University of California, Irvine, Irvine, California, USA
Anesthesiology 115:231-41. 2011..The authors sought to test the predictive value of PPV in a large, multicenter study and to express it using a gray zone approach...
- Impact of pacing modality and biventricular pacing on cardiac output and coronary conduit flow in the post-cardiotomy patientDavid G Healy
Department of Cardiothoracic Surgery, Cork University Hospital, Wilton, Cork, Ireland
Interact Cardiovasc Thorac Surg 7:805-8. 2008..Comparison of cardiac output and coronary conduit flow was performed between VVI and DDD pacing with a single right ventricular lead and ..
- Muscle oxygen transport and utilization in heart failure: implications for exercise (in)toleranceDavid C Poole
Departments of Anatomy and Physiology, and Kinesiology, Kansas State University, Manhattan, KS 66506 5802, USA
Am J Physiol Heart Circ Physiol 302:H1050-63. 2012..As the heart fails, cardiovascular regulation shifts from controlling cardiac output as a means for supplying the oxidative energetic needs of exercising skeletal muscle and other organs to ..
- Pre-ejection period variations predict the fluid responsiveness of septic ventilated patientsMarc Feissel
Intensive Care Unit, Centre Hospitalier, Belfort, France
Crit Care Med 33:2534-9. 2005..We hypothesized that the respiratory change in pre-ejection period (DeltaPEP) would allow the prediction of changes in cardiac index following volume administration in mechanically ventilated septic patients...
- Interrater reliability of cardiac output measurements by transcutaneous Doppler ultrasound: implications for noninvasive hemodynamic monitoring in the EDH Bryant Nguyen
Department of Emergency Medicine, Loma Linda University Medical Center, Loma Linda, CA 92354, USA
Am J Emerg Med 24:828-35. 2006..The purpose of this study is to investigate the interrater agreement of noninvasive cardiac output measurements using transcutaneous Doppler ultrasound technique.
- USCOM (Ultrasonic Cardiac Output Monitors) lacks agreement with thermodilution cardiac output and transoesophageal echocardiography valve measurementsH L A Van den Oever
Department of Anaesthesia, Royal Adelaide Hospital, Adelaide, South Australia, Australia
Anaesth Intensive Care 35:903-10. 2007The USCOM (Ultrasonic Cardiac Output Monitors) device is a non-invasive cardiac output monitor, which utilises transaortic or transpulmonary Doppler flow tracing and valve area estimated using patient height to determine cardiac output...
- Clinical validation of the non-invasive cardiac output monitor USCOM-1A in critically ill patientsL E M van Lelyveld-Haas
Gelderse Vallei Hospital, Department of Intensive Care, Ede, Nijmegen, The Netherlands
Eur J Anaesthesiol 25:917-24. 2008b>Cardiac output is frequently monitored to maintain and improve cardiac function with the primary goal of adequate tissue perfusion...
- Sublingual nitroglycerin used in routine tilt testing provokes a cardiac output-mediated vasovagal responseJanneke Gisolf
Department of Physiology, Academic Medical Center, Cardiovascular Research Institute, Amsterdam, The Netherlands
J Am Coll Cardiol 44:588-93. 2004....
- Cardiac output monitoring in newbornsWillem Pieter de Boode
Radboud University Nijmegen Medical Centre, Department of Neonatology, Nijmegen, The Netherlands
Early Hum Dev 86:143-8. 2010There is an increased interest in methods of objective cardiac output measurement in critically ill patients. Several techniques are available for measurement of cardiac output in children, although this remains very complex in newborns...
- Comparison of pulmonary artery and aortic transpulmonary thermodilution for monitoring of cardiac output in patients with severe heart failure: validation of a novel methodSigrun Friesecke
Department of Internal Medicine B, Division of Cardiology, Pneumology, and Critical Care Medicine, University of Greifswald, Greifswald, Germany
Crit Care Med 37:119-23. 2009..For measurement of cardiac output (CO), transpulmonary thermodilution (TPTD) has recently been adopted into clinical practice as an alternative ..
- Arterial pressure-based cardiac output in septic patients: different accuracy of pulse contour and uncalibrated pressure waveform devicesXavier Monnet
AP HP, Hopital de Bicetre, Service de Reanimation Medicale, 78 rue du General Leclerc, Le Kremlin Bicêtre F 94270, France
Crit Care 14:R109. 2010We compared the ability of two devices estimating cardiac output from arterial pressure-curve analysis to track the changes in cardiac output measured with transpulmonary thermodilution induced by volume expansion and norepinephrine in ..
- Cardiac output derived from arterial pressure waveformJochen Mayer
Department of Anesthesiology and Intensive Care Medicine, Klinikum Ludwigshafen, Ludwigshafen, Germany
Curr Opin Anaesthesiol 22:804-8. 2009b>Cardiac output (CO) and other flow-based hemodynamic variables have become increasingly important to guide treatment of patients undergoing major surgery with expected fluid shifts in the operating room as well as critically ill ICU ..
- Testing the reliability of a new ultrasonic cardiac output monitor, the USCOM, by using aortic flowprobes in anesthetized dogsLester A Critchley
Department of Anesthesia and Intensive Care, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
Anesth Analg 100:748-53, table of contents. 2005We have used an animal model to test the reliability of a new portable continuous-wave Doppler ultrasonic cardiac output monitor, the USCOM...
- Comparison of cardiac output determined by bioimpedance, thermodilution, and the Fick methodMilo Engoren
Department of Anesthesiology, St Vincent Mercy Medical Center, Toledo, OH, USA
Am J Crit Care 14:40-5. 2005b>Cardiac output can be determined by using a variety of methods.
- Cross-comparison of cardiac output trending accuracy of LiDCO, PiCCO, FloTrac and pulmonary artery cathetersMehrnaz Hadian
Department of Critical Care Medicine, University of Pittsburgh Medical Center, 230 Lothrop Street, Pittsburgh, PA 15261, USA
Crit Care 14:R212. 2010..invasive than pulmonary artery catheters (PACs), arterial pulse pressure analysis techniques for estimating cardiac output (CO) have not been simultaneously compared to PAC bolus thermodilution CO (COtd) or continuous CO (CCO) devices...
- Comparison of continuous cardiac output measurements in patients after cardiac surgeryFrank Mielck
Departments of Anesthesiology, and Medical Statistics, University of Goettingen, Germany
J Cardiothorac Vasc Anesth 17:211-6. 2003To investigate in a direct comparison accuracy and precision of continuous cardiac output measurements assessed by continuous pulmonary artery thermodilution technique (TDCCO), continuous pulse contour analysis (PCCO), and noninvasive ..
- Measurement of cardiac output before and after cardiopulmonary bypass: Comparison among aortic transit-time ultrasound, thermodilution, and noninvasive partial CO2 rebreathingMonica Botero
Department of Anesthesiology, University of Florida College of Medicine and the Gainesville Veterans Affairs Medical Center, Gainesville, FL, USA
J Cardiothorac Vasc Anesth 18:563-72. 2004A noninvasive continuous cardiac output system (NICO) has been developed recently...
- Echocardiographic measurement of cardiac output in ratsMichel Slama
Laboratoire de Pharmacologie et de Physiopathologie Cardiovasculaire, Faculte de Medecine, Université de Picardie Jules Vernes, 80054 Amiens, France
Am J Physiol Heart Circ Physiol 284:H691-7. 2003The systematic evaluation of different transthoracic echocardiographic (TTE) methods to determine cardiac output (CO) and the effect of changes in intravascular volume on echocardiographically determined indexes of cardiovascular ..
- Effects of vasodilation on cardiac output measured by PulseCOKoichi Yamashita
Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu, Oko cho, Nankoku Shi, Kochi, 783 8505, Japan
J Clin Monit Comput 21:335-9. 2007The instability of cardiac output (CO) measured by PulseCO (LiDCO Ltd.) during cardiac surgery has been reported...
- Lower cardiac output is associated with greater white matter hyperintensities in older adults with cardiovascular diseaseAngela L Jefferson
Department of Neurology, Alzheimer s Disease Center, Boston University School of Medicine, Boston, Massachusetts 02118, USA
J Am Geriatr Soc 55:1044-8. 2007To preliminarily examine the association between cardiac output, a measure of systemic blood flow, and structural brain magnetic resonance imaging indices of white matter hyperintensities (WMHs).
- Measurement of cardiac output: a comparison between transpulmonary thermodilution and uncalibrated pulse contour analysisS G Sakka
Department of Anaesthesiology and Operative Intensive Care Medicine, Medical Center Cologne Merheim, Cologne, Germany
Br J Anaesth 99:337-42. 2007Recently, continuous monitoring of cardiac output (CO) based on pulse contour analysis (Vigileo) has been introduced into practice...
- Arterial pressure-based cardiac output monitoring: a multicenter validation of the third-generation software in septic patientsDaniel De Backer
Department of Intensive Care, Erasme University Hospital, Universite Libre de Bruxelles, Route de Lennik 808, 1070 Brussels, Belgium
Intensive Care Med 37:233-40. 2011Second-generation FloTrac software has been shown to reliably measure cardiac output (CO) in cardiac surgical patients. However, concerns have been raised regarding its accuracy in vasoplegic states...
- Cardiovascular Responses to Sleep Apnea in Tetraplegia: A Pilot StudyJill M Wecht; Fiscal Year: 2010..is heightened sympathetic nervous system activity stemming from repetitive apneic events, although falls in cardiac output that accompany large negative intrathoracic pressure swings, and repetitive hypoxia/reoxygenation associated ..
- ORGANIZATION OF CENTRAL SYMPATHETIC PATHWAYSPatrice G Guyenet; Fiscal Year: 2013..PUBLIC HEALTH RELEVANCE: A brief period of asphyxia activates breathing, blood pressure and the cardiac output. Asphyxia also produces arousal from sleep which enables corrective behavior for example in case of airway ..
- Conference on Autonomic Regulation of Cardiovascular Function in Health and DiseaMartin Frank; Fiscal Year: 2012..true in those conditions that require a high level of sympathetic tone to compensate for an abnormal cardiac output or where sympathetic nervous activity sustains arterial pressure in a range that is clearly detrimental to ..
- Intrathoracic Pressure Regulator for ResuscitationKeith G Lurie; Fiscal Year: 2011..the rest of the body thereby a) significantly enhancing blood return to the heart and consequently increasing cardiac output and blood pressure and b) uniquely lowering intracranial pressure thereby increasing cerebral perfusion...
- Mechanisms of Vasovagal SyncopeJulian M Stewart; Fiscal Year: 2013..apply this mechanism to a model of orthostatic stress, lower body negative pressure (LBNP), while measuring cardiac output by inert gas rebreathing, regional blood volume, and regional blood flow using plethysmographic techniques ..
- Respiratory motor control and blood pressure regulation after spinal cord injuryALEXANDER VLADIMIROVICH OVECHKIN; Fiscal Year: 2013..of managing their unstable blood pressure which frequently results in persistent hypotension due to decreased cardiac output and autonomic nervous system dysfunction...
- Molecular control of differential peptide transmitter exocytosis.COREY B SMITH; Fiscal Year: 2013..multiple processes that prepare for defense or escape, including generalized analgesia (enkephalin), increased cardiac output (elevated catecholamines), blood flow to skeletal muscle (atrial natriuretic factor, Neuropeptide Y) and blood ..
- Monitoring of Cardiovascular Function in Infants By Transcutaneous Dye DilutionIstvan Seri; Fiscal Year: 2013DESCRIPTION (provided by applicant): Cardiac output (CO) and measures of cardiac preload (central blood volume, CBV) and systemic vascular resistance (SVR) are critical clinical parameters of circulatory function...
- Peptide Therapy for Pulmonary Arterial HypertensionJawaharlal M Patel; Fiscal Year: 2013..increased pulmonary vascular resistance, vascular remodeling, right ventricular (RV) failure, and low cardiac output. Despite its profound clinical consequences, therapeutic advances over the past 25 years have modestly ..
- Novel non-invasive device for treatment of elevated intracranial pressuresKeith G Lurie; Fiscal Year: 2011..relative to the rest of the body thereby a) enhancing blood return to the heart and consequently increasing cardiac output and blood pressure and b) lowering intracranial pressure thereby increasing cerebral perfusion...
- Novel bundled mechanical and pharmacological CPR platformAnja Metzger; Fiscal Year: 2012..within the thorax relative to the rest of the body that enhances venous blood return to the heart, increases cardiac output and systemic arterial blood pressure, lowers right atrial and pulmonary artery pressures, lowers intracranial ..
- L-arginine supplement for the prevention of calcineurin inhibitor nephrotoxicityW Ray Kim; Fiscal Year: 2011..Additionally, the effects of oral L-arginine on glomerular filtration rate, cardiac output, systemic vascular resistance, endothelial function, plasma arginine level and urinary cyclic-GMP will be ..
- Resuscitation using novel impedance threshold devices in pediatricsKeith G Lurie; Fiscal Year: 2013..pressure regulation (IPR), enhances negative intrathoracic pressure and thus will augment preload, improve cardiac output, enhance cerebral oxygenation, and delay or prevent the progression of reversible shock to irreversible ..
- Free Hemoglobin Potentiates Pulmonary Vascular Dysfunction in Acute Lung InjuryJULIE ANNE BASTARACHE; Fiscal Year: 2013..pressure, pulmonary vascular resistance, transpulmonary resistance), cardiac dysfunction (as measured by cardiac output and mixed venous oxygen saturation), non-pulmonary organ dysfunction, and biomarkers of endothelial injury and ..
- Pulmonary Vascular Changes in Early Chronic Obstructive Pulmonary Disease (COPD)R Graham Barr; Fiscal Year: 2011..We found impaired endothelial function and reduced cardiac output with preserved LV function in early COPD among smokers in two cohort studies, the EMCAP Study and the Multi-..
- Cardiopulmonary structure and function in Multi-Ethnic Study of AtherosclerosisR Graham Barr; Fiscal Year: 2013..of airflow obstruction and emphysema on CT scan with reduced LV end-diastolic volume, LV stroke volume and cardiac output but not LV-EF on magnetic resonance imaging, particularly among smokers...
- Mechanisms of Meditation in Hypertension in BlacksRobert Schneider; Fiscal Year: 2010..reactivity to lab stressors;hemodynamic responses, comprising heart rate, blood pressure, stroke volume, cardiac output, and total peripheral resistance;arterial compliance, and cardiac autonomic nervous system tone using heart ..
- Self-Sensing Physiologic Control of a Rotary Mag Lev LVADJAMES FARLEY WALTON; Fiscal Year: 2010..controller are its ability to use motor and magnetic bearing signals to adjust LVAD output in response to cardiac output changes through the use of differential pressure and flow estimators all while avoiding suction...
- Genetic Regulation of Metabolic and Fibrotic Programs in Hypertrophic HeartM A Q Siddiqui; Fiscal Year: 2013..to stress and increased demand by mounting an adaptive or compensatory hypertrophic response to normalize cardiac output. With prolonged stress, this adaptive phase devolves to a maladaptive or decompensatory hypertrophy marked by ..
- Beta2-Adrenergic Receptor Gene Variation and Cardiovascular Control in HumansJohn H Eisenach; Fiscal Year: 2012..for glycine at position 16 (Gly16) and glutamate at position 27 (Glu27) (haplotype 1) will demonstrate greater cardiac output and lower systemic vascular resistance during mental stress and isometric handgrip exercise than individuals ..
- Neurohumoral control of veins in hypertensionGregory D Fink; Fiscal Year: 2013..rats using a number of whole body measures including blood pressure, mean circulatory filling pressure, cardiac output, and fluid volume distribution using bioimpedance...
- Excitability of afferents evoking the exercise pressor reflexVictor Ruiz-Velasco; Fiscal Year: 2013..increasing blood flow and oxygen to exercising muscles, include reflex increases in arterial blood pressure, cardiac output and ventilation...
- The role of cochlear pericytes in control of cochlear microcirculationXiao Rui Shi; Fiscal Year: 2009..The volume of cochlear blood flow is extremely small (on the order of 1/1 000 000 of total cardiac output), yet critically important for normal hearing...
- Nuclear magnetic Tirho relaxation in acute and chronic myocardial infarctionsWalter R T Witschey; Fiscal Year: 2013..Ultimately, cardiac output cannot be sustained under such progressive heart enlargement...
- Physiological reactivity to acute stress during pregnancyLISA MICHELLE CHRISTIAN; Fiscal Year: 2010..e., cardiac output, total peripheral resistance)...
- Effects of maternal cortisol on fetal and neonatal growth and metabolismMaureen Keller-Wood; Fiscal Year: 2013..growth and metabolism primarily by reducing maternal volume expansion, and the normal increases in maternal cardiac output and uteroplacental blood flow that are essential for acceleration of fetal growth in the late gestation, and ..
- Perinatal regulation of endothelial NOSStephen M Black; Fiscal Year: 2010..and much of our therapies are focused on altering pulmonary vascular resistance in attempt to optimize cardiac output while maintaining enough pulmonary blood flow to ensure adequate systemic oxygenation...
- Circulatory system and integrated muscle tissue for drug and tissue toxicityGeorge A Truskey; Fiscal Year: 2013..Skeletal muscle is important for drug and toxicity testing given the relative size of the muscle mass and cardiac output that passes through muscle beds, the key role of muscle in energy substrate metabolism and diabetes, its role ..
- Mechanisms of Cardiac Function and Cerebral Vascular Control during Heat StressRobert Matthew Brothers; Fiscal Year: 2010..Specifically we will examine: 1) the role of decreased central venous pressure and cardiac output during combined heat and orthostatic stress on CBF, 2) the relative contributions of reduced arterial CO2 ..
- Frequency-dependent modulation of cardiac myofilament function in health/diseasePAULUS ML JANSSEN; Fiscal Year: 2013DESCRIPTION (provided by applicant): Maintenance of sufficient cardiac output to provide the body and the heart itself with nutrients and oxygen is a must to sustain life...
- Improving the Kinetics and Reliability of Continuous Glucose MonitoringBrett D Mensh; Fiscal Year: 2012..because the blood flow to this central, protected space is copious and robust to changes in temperature and cardiac output, and because the glucose kinetics of the peritoneal space are known to be fast...
- CARDIAC CONTRACTILE KINETICSMichael Regnier; Fiscal Year: 2009..a mechanism for greater cellular level contractile control that is required for beat-to-beat regulation of cardiac output. Direct evidence to support this idea is difficult to obtain, in part due to an inability to alter crossbridge ..
- A novel device for improving sepsis outcomes through hemodynamic optimizationBrett D Mensh; Fiscal Year: 2013..to monitor patient responses to fluid infusion, particularly those that can safely and accurately measure cardiac output or detect the onset of fluid overload. In response to this need we have developed the OmniSense catheter...
- Entrainment-based mechanical ventilationChi Sang Poon; Fiscal Year: 2010..work of breathing and risk of barotrauma, as well as decreases in pulmonary gas exchange efficiency and in cardiac output. Current generation of mechanical ventilators either control the breathing rhythm completely independent of ..
- The Stress of Chronic Disease: Mineralocorticoid Mediation of MoodAlan Kim Johnson; Fiscal Year: 2013..lead us to hypothesize that adrenal mineralocorticoids released in the course of attempting to maintain the cardiac output of a failing heart are depressivogenic through their action on the central nervous system...
- Preoperative Therapy for Prevention of Postoperative Low Cardiac Output SyndromeD Woodrow Benson; Fiscal Year: 2010DESCRIPTION (provided by applicant): Myocardial dysfunction and resulting low cardiac output syndrome (LCOS) contribute significantly to postoperative morbidity and mortality in pediatric heart surgery...
- mAKAP-orchestrated phosphorylation events: regulation of PDE4D3Kimberly L Dodge Kafka; Fiscal Year: 2010..is the major compensatory mechanism by which the heart responds to a continued, increased demand for cardiac output. Ultimately, cardiac hypertrophy leads to progression into cardiac disease and to heart failure...
- RSK Regulation of NFATc and Cardiac Myocyte HypertrophyAlejandra Negro; Fiscal Year: 2010..Although cardiac hypertrophy can maintain cardiac output in response to elevated wall stress, sustained cardiac hypertrophy is often accompanied by maladaptive ..
- Na+/Ca2+ Exchanger type-1 in Arterial Contraction and Salt-induced HypertensionJin Zhang; Fiscal Year: 2013..Blood flow (to determine cardiac output, CO) and telemetric arterial BP will be measured in conscious, freely moving mice...
- PHYSIOLOGY OF FLUOROCARBON OXYGEN TRANSPORTLELAND CLARK; Fiscal Year: 1992..Arterial and venous blood gases, cardiac output and ECG will be monitored. PH, blood lactate and glucose will also be measured...
- Inflammatory response of aging heart to surgical myocardial ischemiaXianzhong Meng; Fiscal Year: 2013DESCRIPTION (provided by applicant): Elderly patients are vulnerable to low cardiac output syndrome after cardiac surgery that obligates global myocardial ischemia and reperfusion (I/R)...
- Circulatory Dysfunction in Chronic Fatigue SyndromeJulian Stewart; Fiscal Year: 2004..Central hypovolemia causes decreased cardiac output, reflex tachycardia and reduced cerebral blood flow...
- Multimodal biophysical markers of vascular disease in hemoglobinopathiesLonnie K Zeltzer; Fiscal Year: 2013..varying percent hemoglobin S in order to separate the measurement components due to altered blood rheology and cardiac output from the components reflecting vascular status and the autonomic function of interest...
- Effects of Mechanical Unloading on Myocardial Function and Structure in HumansJosef Stehlik; Fiscal Year: 2013..LVADs are used as a bridge to transplant or as permanent therapy. The benefits of restoring normal cardiac output through LVAD support are well described, but our understanding of the effects and possible consequences of ..
- Intrathoracic Pressure Regulation for the Treatment of Septic ShockKeith Lurie; Fiscal Year: 2009..thorax relative to the rest of the body thereby a) enhancing venous blood return to the heart b) increasing cardiac output and systemic arterial blood pressure, c) lowering right atrial and pulmonary artery pressures, and d) lowering ..
- Ethanol on Excitation-Contraction in Cardiac CellsAndrew Thomas; Fiscal Year: 2009..Features of alcoholic cardiomyopathy include decreased cardiac output, impaired myocardial contractility and atrial dysrhythmias...
- Randomized Clinical Trials for Pediatric Heart DiseaseJ Philip Saul; Fiscal Year: 2010..the effects of preoperative intravenous methypredisolone (IVMP) to placebo on the Primary Endpoint of low cardiac output state (LCOS) or death at 36 hours following neonatal CPB...
- Skeletal Muscle Basis for Improved Exercise Endurance in AC5 KOStephen F Vatner; Fiscal Year: 2013..major goals of physicians treating patients with cardiovascular disease, can be achieved either by improving cardiac output and blood flow to skeletal muscle, or by improving energy metabolism in skeletal muscle, or both...
- Engineered Induction of a Stem Cell Homing ResponseJEFFREY MICHAEL KARP; Fiscal Year: 2013..with an exogenous cell source) natural stem cell homing mechanisms show promise to preserve and restore cardiac output following myocardial infarction...
- Early Detection of Changes in Pulmonary Gas Exchange by Hyperpolarized Xe MRIBastiaan Driehuys; Fiscal Year: 2013..blood-selective 129Xe gas exchange MRI 2) Establish image reproducibility as a function of time, posture, and cardiac output, and 3) Image the temporal evolution of regional gas exchange during radiation therapy...
- Exercise adaptations in mitochondrial myopathy: therapeutic implicationsRonald G Haller; Fiscal Year: 2012..effects on muscle and cardiovascular function will be assessed by monitoring peak work, oxygen utilization, cardiac output and stroke volume in cycle exercise, and by monitors of quality of life...
- Compliant Thoracic Artificial LungsKEITH ELLIOT COOK; Fiscal Year: 2012..work also indicates that the fluid mechanical impedance of these devices can cause a significant reduction in cardiac output (CO) when attached in the PA- PA configuration...
- Mechanism for Regulation of Phospholipase C by G ProteinAlan V Smrcka; Fiscal Year: 2013..One of the characteristics of progression to heart failure is reduced cardiac output due to decreased contractility and cardiac hypertrophy...
- Rescue of Beta-Adrenergic Cardiomyopathy by Inhibition of Adenylyl CyclaseDorothy E Vatner; Fiscal Year: 2012..Tg cardiomyopathies by inhibition of AC5 permits enhanced exercise performance which is due to (1) improved cardiac output and stroke volume, (2) improved coronary reserve, and (3) enhanced nitric oxide (NO) signaling...
- Long Term Treatment of Modified Stem Cells for Pulmonary HypertensionDAVID BRENDAN CASEY; Fiscal Year: 2010..is to investigate the effect of unmodified and gene modified MSCs on pulmonary arterial and wedge pressure and cardiac output and on pulmonary vasodilator response to acetylcholine for periods up to 6 months after moncrotaline ..
- Remote and non-invasive continuous cardiopulmonary monitoring using low-power FMKIRILL S contact MOSTOV; Fiscal Year: 2010..radar (MFMR) can detect changes in the following four physiological variables: heart rate, respiratory rate, cardiac output and respiratory tidal volume...
- The role of RGS proteins in the parasympathetic control of heart rateKEVIN D WICKMAN; Fiscal Year: 2013DESCRIPTION (provided by applicant): Cardiac output adjusts on a beat-to-beat basis due to the changing balance of parasympathetic and sympathetic input to the heart. G protein signaling pathways are fundamental to this important process...
- CARDIAC HYPERTROPHIC INTRACELLULAR SIGNALING PATHWAYSJeffrey Robbins; Fiscal Year: 2013..While hypertrophy can initially be a compensatory response that temporarily augments cardiac output, prolonged hypertrophy can be deleterious and eventually leads to heart failure and/or sudden death...
- Ca2+/CaM-Dependent Protein Kinase II: A Novel Target in Heart FailureHoward Schulman; Fiscal Year: 2011DESCRIPTION (provided by applicant): Heart disease converts to the clinical syndrome of heart failure when the cardiac output is inadequate to meet metabolic requirements...
- Role of the Molecular Circadian Clock within the HeartMARTIN ELLIOT YOUNG; Fiscal Year: 2012..Humans exhibit marked circadian rhythms in multiple cardiovascular (CV) parameters, including heart rate, cardiac output, and blood pressure...
- Abnormal Intracellular Calcium Release in Heart FailureSandor Gyorke; Fiscal Year: 2013..is an increasingly prevalent disease that occurs when the cardiac muscle is unable to maintain a sufficient cardiac output. HF patients suffer, and eventually die from either progressive failure of cardiac mechanical function (pump ..
- The Effects of Perceived Discrimination on Mental and Physical HealthBRENDA N MAJOR; Fiscal Year: 2010..g., vascular resistance) or anger (e.g., cardiac output)...
- PITCH HF Right Ventricular Pulmonary Vascular Reserve Ancillary StudyGREGORY DYER LEWIS; Fiscal Year: 2013..study is that abnormal pulmonary vasodilatory capacity, as reflected by steep PAP increment relative to cardiac output (i.e...
- BAROREFLEX AND POSTERIOR HYPOTHALAMIC NEUROPEPTIDE-YJohn Martin; Fiscal Year: 1991..The animals used in these experiments will be instrumented so that cardiac output can be simultaneously measured in order to determine the effect of sympathetic and/or parasympathetic activity ..
- SURGICAL STUDIES OF SEVERE RESPIRATORY FAILUREJoseph Zwischenberger; Fiscal Year: 2004..Adverse effects of permissive hypercapnia and the associated respiratory acidosis include increased cardiac output, organ blood flow and intracranial pressure...
- Effects of Vasoactive Drugs on Perfusion in Septic ShockPatrick Murray; Fiscal Year: 2005..may lead to refractorv hypotension (septic shock) and multiple organ system failure (MOSF). Despite increased cardiac output and oxygen delivery, death often ensues from refractory hypotension or subsequent MOSF...
- COMPLEMENT-DEPENDENT PROSTAGLANDIN SYNTHESIS IN SEPSISMitchell Fink; Fiscal Year: 1991..will employ a rabbit model of endotoxemia that is characterized by low systemic vascular resistance and high cardiac output; i.e., the model satisfactorily replicates the systemic hemodynamic profile of human sepsis...
- NO Metabolic Control in PregnancyThomas Hintze; Fiscal Year: 2006The cardiovascular adjustments that occur during pregnancy include chronic increases in cardiac output, falls in total peripheral vascular resistance and tachycardia...
- TRANSFUSION TRIGGER EXTENSION BY PLASMA EXPANDERSMarcos Intaglietta; Fiscal Year: 2009..These effects occur also in the microcirculation of the heart, causing heart function, and cardiac output to decrease...
- LUNG VASCULAR EFFECTS OF HIGH FREQUENCY VENTILATIONMUKUL BANERJEE; Fiscal Year: 1992..substances, eicosanoids and atrial natriuretic factor (ANF) are released during substances can influence cardiac output, pulmonary and systemic vascular pressures and water balance...
- PHYSIOLOGIC RESPONSE TO THERMAL INJURYEDWARD PAVLIN; Fiscal Year: 1990Victims of thermal injury undergo profound physiologic changes; e.g. increases in basal metabolic rate, cardiac output and glomerular filtration rate...
- ADAPTATIONS TO EXERCISE IN OLDER HYPERTENSIVE SUBJECTSAli Ehsani; Fiscal Year: 2000..exercise-training can reduce BP; (2) to elucidate mechanisms underlying reduction of BP by evaluation of cardiac output, total peripheral resistance, arterial stiffness, sympathetic nervous system activity, and blood volume; (3) ..
- Neural and non-neural modulators of skin blood flow and sweating in humansCRAIG CRANDALL; Fiscal Year: 2009DESCRIPTION (provided by applicant): A large fraction of cardiac output (i.e...
- Mechanisms Mediating Hypotension to Anthrax Lethal ToxinMichael J Kenney; Fiscal Year: 2010..sympathetic nerve outflow, the fundamental link between central sympathetic neural circuits and regulation of cardiac output, vascular resistance, and arterial blood pressure...