diagnostic errors

Summary

Summary: Incorrect diagnoses after clinical examination or technical diagnostic procedures.

Top Publications

  1. ncbi Cognitive forcing strategies in clinical decisionmaking
    Pat Croskerry
    Department of Emergency Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    Ann Emerg Med 41:110-20. 2003
  2. pmc Overdiagnosis of malaria in patients with severe febrile illness in Tanzania: a prospective study
    Hugh Reyburn
    London School of Hygiene and Tropical Medicine, London WCIE 7HT
    BMJ 329:1212. 2004
  3. pmc Malaria misdiagnosis in Uganda--implications for policy change
    Joan Nankabirwa
    Malaria Consortium, Africa Regional Office, Kampala, Uganda
    Malar J 8:66. 2009
  4. ncbi The importance of cognitive errors in diagnosis and strategies to minimize them
    Pat Croskerry
    Department of Emergency Medicine, Dalhousie University Faculty of Medicine, Halifax, Nova Scotia, Canada
    Acad Med 78:775-80. 2003
  5. ncbi Overconfidence as a cause of diagnostic error in medicine
    Eta S Berner
    Department of Health Services Administration, School of Health Professions, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Am J Med 121:S2-23. 2008
  6. ncbi Diagnostic error in internal medicine
    Mark L Graber
    Department of Veterans Affairs Medical Center, Northport, NY 11768, USA
    Arch Intern Med 165:1493-9. 2005
  7. ncbi Errors in laboratory medicine
    Pierangelo Bonini
    Universita Vita Salute San Raffaele, Cattedra di Biochimica Clinica, Via Olgettina 58, 20132 Milan, Italy
    Clin Chem 48:691-8. 2002
  8. ncbi Preanalytical quality improvement: from dream to reality
    Giuseppe Lippi
    Clinical Chemistry and Hematology Laboratory, Academic Hospital of Parma, Parma, Italy
    Clin Chem Lab Med 49:1113-26. 2011
  9. ncbi Diagnostic error in medicine: analysis of 583 physician-reported errors
    Gordon D Schiff
    Division of General Medicine and Primary Care, Brigham and Women s Hospital, 1620 Tremont St, Third Floor, Boston, MA 02120, USA
    Arch Intern Med 169:1881-7. 2009
  10. pmc Interpreting overdiagnosis estimates in population-based mammography screening
    Rianne De Gelder
    Department of Public Health, Erasmus MC, Room AE 137, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    Epidemiol Rev 33:111-21. 2011

Detail Information

Publications279 found, 100 shown here

  1. ncbi Cognitive forcing strategies in clinical decisionmaking
    Pat Croskerry
    Department of Emergency Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    Ann Emerg Med 41:110-20. 2003
    Cognitive errors underlie most diagnostic errors that are made in the course of clinical decisionmaking in the emergency department. These errors are universal and are prevalent in the special milieu of the ED...
  2. pmc Overdiagnosis of malaria in patients with severe febrile illness in Tanzania: a prospective study
    Hugh Reyburn
    London School of Hygiene and Tropical Medicine, London WCIE 7HT
    BMJ 329:1212. 2004
    ..To study the diagnosis and outcomes in people admitted to hospital with a diagnosis of severe malaria in areas with differing intensities of malaria transmission...
  3. pmc Malaria misdiagnosis in Uganda--implications for policy change
    Joan Nankabirwa
    Malaria Consortium, Africa Regional Office, Kampala, Uganda
    Malar J 8:66. 2009
    ..In this study, the policy implications of such recommendations are revisited...
  4. ncbi The importance of cognitive errors in diagnosis and strategies to minimize them
    Pat Croskerry
    Department of Emergency Medicine, Dalhousie University Faculty of Medicine, Halifax, Nova Scotia, Canada
    Acad Med 78:775-80. 2003
    ..A critical subset of diagnostic errors arises through cognitive errors, especially those associated with failures in perception, failed heuristics, ..
  5. ncbi Overconfidence as a cause of diagnostic error in medicine
    Eta S Berner
    Department of Health Services Administration, School of Health Professions, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Am J Med 121:S2-23. 2008
    ....
  6. ncbi Diagnostic error in internal medicine
    Mark L Graber
    Department of Veterans Affairs Medical Center, Northport, NY 11768, USA
    Arch Intern Med 165:1493-9. 2005
    ..The goal of this study was to determine the relative contribution of system-related and cognitive components to diagnostic error and to develop a comprehensive working taxonomy...
  7. ncbi Errors in laboratory medicine
    Pierangelo Bonini
    Universita Vita Salute San Raffaele, Cattedra di Biochimica Clinica, Via Olgettina 58, 20132 Milan, Italy
    Clin Chem 48:691-8. 2002
    ..The problem of medical errors has recently received a great deal of attention, which will probably increase. In this minireview, we focus on this issue in the fields of laboratory medicine and blood transfusion...
  8. ncbi Preanalytical quality improvement: from dream to reality
    Giuseppe Lippi
    Clinical Chemistry and Hematology Laboratory, Academic Hospital of Parma, Parma, Italy
    Clin Chem Lab Med 49:1113-26. 2011
    ....
  9. ncbi Diagnostic error in medicine: analysis of 583 physician-reported errors
    Gordon D Schiff
    Division of General Medicine and Primary Care, Brigham and Women s Hospital, 1620 Tremont St, Third Floor, Boston, MA 02120, USA
    Arch Intern Med 169:1881-7. 2009
    ..To better understand the types, causes, and prevention of such errors, we surveyed clinicians to solicit perceived cases of missed and delayed diagnoses...
  10. pmc Interpreting overdiagnosis estimates in population-based mammography screening
    Rianne De Gelder
    Department of Public Health, Erasmus MC, Room AE 137, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    Epidemiol Rev 33:111-21. 2011
    ..Calculations based on earlier screening program phases may overestimate overdiagnosis by a factor 4. Sufficient follow-up and agreement regarding the chosen estimator are needed to obtain reliable estimates...
  11. ncbi Malaria misdiagnosis: effects on the poor and vulnerable
    Mark Amexo
    Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK
    Lancet 364:1896-8. 2004
    ..Much better direct evidence is needed about why and how misdiagnosis affects the poor and vulnerable...
  12. ncbi Pseudohyponatremia revisited: a modern-day pitfall
    Philip Fortgens
    Division of Chemical Pathology, University of Cape Town and National Health Laboratory Service, Groote Schuur Hospital, Cape Town, South Africa
    Arch Pathol Lab Med 135:516-9. 2011
    ....
  13. ncbi Effect of availability bias and reflective reasoning on diagnostic accuracy among internal medicine residents
    Silvia Mamede
    Department of Psychology, Erasmus University Rotterdam, Burgemeester Oudlaan 50, Rotterdam, 3062 PA, The Netherlands
    JAMA 304:1198-203. 2010
    b>Diagnostic errors have been associated with bias in clinical reasoning. Empirical evidence on the cognitive mechanisms underlying biases and effectiveness of educational strategies to counteract them is lacking.
  14. ncbi Patient safety strategies targeted at diagnostic errors: a systematic review
    Kathryn M McDonald
    Stanford Center for Health Policy Center for Primary Care and Outcomes Research, Stanford University, Stanford, California, USA
    Ann Intern Med 158:381-9. 2013
    ..This systematic review analyzed evaluations of interventions to prevent diagnostic errors. Searches used MEDLINE (1966 to October 2012), the Agency for Healthcare Research and Quality's Patient ..
  15. pmc Errors of diagnosis in pediatric practice: a multisite survey
    Hardeep Singh
    Houston Veterans Affairs Health Services Research and Development Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas, USA
    Pediatrics 126:70-9. 2010
    We surveyed pediatricians to elicit their perceptions regarding frequency, contributing factors, and potential system- and provider-based solutions to address diagnostic errors.
  16. ncbi Relating faults in diagnostic reasoning with diagnostic errors and patient harm
    Laura Zwaan
    Department of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands
    Acad Med 87:149-56. 2012
    The relationship between faults in diagnostic reasoning, diagnostic errors, and patient harm has hardly been studied. This study examined suboptimal cognitive acts (SCAs; i.e...
  17. ncbi Identifying diagnostic errors in primary care using an electronic screening algorithm
    Hardeep Singh
    Division of Health Policy and Quality, Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey Veterans Affairs Medical Center, Baylor College of Medicine, 2002 Holcombe Boulevard, Houston, TX 77030, USA
    Arch Intern Med 167:302-8. 2007
    b>Diagnostic errors are the leading basis for malpractice claims in primary care, yet these errors are underidentified and understudied...
  18. ncbi Analytical error and interference in immunoassay: minimizing risk
    Catharine M Sturgeon
    Department of Clinical Biochemistry, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, UK
    Ann Clin Biochem 48:418-32. 2011
    ....
  19. pmc Rate of over-diagnosis of breast cancer 15 years after end of Malmö mammographic screening trial: follow-up study
    Sophia Zackrisson
    Department of Clinical Sciences in Malmo, Epidemiological Research Group, Lund University, Malmo University Hospital, SE 205 02, Malmo, Sweden
    BMJ 332:689-92. 2006
    ..To evaluate the rate of over-diagnosis of breast cancer 15 years after the end of the Malmö mammographic screening trial...
  20. ncbi Diagnostic errors in medicine: a case of neglect
    Mark Graber
    VA Medical Center, Northport, NW, USA
    Jt Comm J Qual Patient Saf 31:106-13. 2005
    ..Compared with other types of medical error, however, diagnostic errors receive little attention-a major factor in perpetuating unacceptable rates of diagnostic error...
  21. ncbi Identification of G8 rotavirus strains determined as G12 by rotavirus genotyping PCR: updating the current genotyping methods
    Farah Aladin
    Health Protection Agency, Centre for Infections, 61 Colindale Avenue, London, NW9 5HT, United Kingdom
    J Clin Virol 47:340-4. 2010
    ..As part of strain surveillance for the European Rotavirus Network (EuroRotaNet) a cluster (n=29) of G8 strains was detected in the UK between February and May 2009...
  22. ncbi Missed and delayed diagnoses in the ambulatory setting: a study of closed malpractice claims
    Tejal K Gandhi
    Brigham and Women s Hospital and Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Ann Intern Med 145:488-96. 2006
    ..Although missed and delayed diagnoses have become an important patient safety concern, they remain largely unstudied, especially in the outpatient setting...
  23. ncbi Miscoding, misclassification and misdiagnosis of diabetes in primary care
    S de Lusignan
    Department of Health Care Management and Policy, Faculty of Business, Economics and Law, University of Surrey, Guildford, UK
    Diabet Med 29:181-9. 2012
    ..To determine the effectiveness of self-audit tools designed to detect miscoding, misclassification and misdiagnosis of diabetes in primary care...
  24. ncbi The Sinus, Allergy and Migraine Study (SAMS)
    Eric Eross
    Scottsdale Headache Center at Arizona Neurological Institute, Scottsdale, AZ 85255, USA
    Headache 47:213-24. 2007
    ....
  25. pmc Breast cancer incidence and overdiagnosis in Catalonia (Spain)
    Montserrat Martínez-Alonso
    Basic Medical Sciences Department, Biomedical Research Institut of Lleida IRBLLEIDA, Alcalde Rovira Roure 80, Lleida, 25198, Catalonia, Spain
    Breast Cancer Res 12:R58. 2010
    ..The aims of this study were: first, to model invasive BC incidence trends in Catalonia (Spain) taking into account reproductive and screening data; and second, to quantify the extent of BC overdiagnosis...
  26. ncbi The misdiagnosis of cluster headache: a nonclinic, population-based, Internet survey
    J A Klapper
    Colorado Neurology and Headache Center, Denver 80218, USA
    Headache 40:730-5. 2000
    ..Using International Headache Society criteria for cluster headache, 87% of the respondents should have been correctly diagnosed by the first physician seen...
  27. pmc Features involved in the diagnostic delay of cluster headache
    J A van Vliet
    Department of Neurology, Leiden University Medical Centre, 2300 RC Leiden, Netherlands
    J Neurol Neurosurg Psychiatry 74:1123-5. 2003
    ..Besides, while adequate and evidence based treatment is available in diagnosed cases, CH seems to be poorly managed. The authors performed a nationwide survey among CH patients, and looked for factors involved in the diagnostic delay...
  28. pmc Influence of a light meal on routine haematological tests
    Giuseppe Lippi
    Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico Biomediche University of Verona, Ospedale Policlinico G B Rossi, Verona, Italy
    Blood Transfus 8:94-9. 2010
    ..However, no clear indications about fasting requirements exist for routine haematological tests, nor has the influence of meals been assessed...
  29. ncbi Profiles in patient safety: A "perfect storm" in the emergency department
    Samuel G Campbell
    Department of Emergency Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    Acad Emerg Med 14:743-9. 2007
    ..They offer practical suggestions whereby clinicians may decrease their chances of becoming victims of these influences...
  30. ncbi Clinical cognition and diagnostic error: applications of a dual process model of reasoning
    Pat Croskerry
    Department of Emergency Medicine, Dalhousie University, NS, Canada
    Adv Health Sci Educ Theory Pract 14:27-35. 2009
    ..Importantly, specific operating characteristics of the model explain how diagnostic failure occurs...
  31. ncbi Checklists to reduce diagnostic errors
    John W Ely
    Department of Family Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA
    Acad Med 86:307-13. 2011
    b>Diagnostic errors are common and can often be traced to physicians' cognitive biases and failed heuristics (mental shortcuts)...
  32. pmc Missed opportunities to initiate endoscopic evaluation for colorectal cancer diagnosis
    Hardeep Singh
    Houston VA HSR and D Center of Excellence and The Center of Inquiry to Improve Outpatient Safety Through Effective Electronic Communication, Michael E DeBakey Veterans Affairs Medical Center and the Section of Health Services Research, Baylor College of Medicine, Houston, Texas, USA
    Am J Gastroenterol 104:2543-54. 2009
    ..Our objective was to describe missed opportunities to diagnose CRC before endoscopic referral, in terms of patient characteristics, nature of clinical clues, and types of diagnostic-process breakdowns involved...
  33. ncbi Estimates of overdiagnosis of invasive breast cancer associated with screening mammography
    Stephen Morrell
    School of Public Health, University of Sydney, Sydney, NSW, Australia
    Cancer Causes Control 21:275-82. 2010
    ..To estimate the extent of overdiagnosis of invasive breast cancer associated with screening in New South Wales, Australia, a population with a well-established mammography screening program which has achieved full geographic coverage...
  34. ncbi Iatrogenic harm caused by diagnostic errors in fibrodysplasia ossificans progressiva
    Joseph A Kitterman
    Department of Pediatrics, Cardiovascular Research Institute, University of California San Francisco, California 94143, USA
    Pediatrics 116:e654-61. 2005
    Little is known about diagnostic errors for a disease worldwide. Such errors could alter the disease's natural history, especially if unwarranted interventions cause irreversible harm...
  35. ncbi Missed and delayed diagnoses in the emergency department: a study of closed malpractice claims from 4 liability insurers
    Allen Kachalia
    Division of General Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Ann Emerg Med 49:196-205. 2007
    b>Diagnostic errors in the emergency department (ED) are an important patient safety concern, but little is known about their cause. We identify types and causes of missed or delayed diagnoses in the ED.
  36. ncbi Misdiagnosis of COPD and asthma in primary care patients 40 years of age and over
    David G Tinkelman
    Health Initiatives, National Jewish Medical and Research Center, Denver, USA
    J Asthma 43:75-80. 2006
    ..Increased awareness of the differences between the two conditions is needed to promote optimal patient management and treatment...
  37. pmc Clinical problem solving and diagnostic decision making: selective review of the cognitive literature
    Arthur S Elstein
    Department of Medical Education, University of Illinois College of Medicine, Chicago, IL 60612 7309, USA
    BMJ 324:729-32. 2002
  38. ncbi Inferences of clinical diagnostic reasoning and diagnostic error
    Anton E Lawson
    Organismal, Integrative and Systems Biology, School of Life Sciences, Arizona State University, Tempe, AZ 85287, United States
    J Biomed Inform 44:402-12. 2011
    ..Nevertheless, we propose that raising such reasoning to the conscious level reveals not its basic pattern and basic inferences, it also reveals where errors can and do occur and how such errors might be reduced or even eliminated...
  39. ncbi Diagnostic and therapeutic trajectory of cluster headache patients in Flanders
    E Van Alboom
    Department of Neurology of Ghent University Hospital, Ghent, Belgium
    Acta Neurol Belg 109:10-7. 2009
    ..A fraction of cluster headache (CH) patients face diagnostic delay, misdiagnosis, undertreatment and mismanagement. Specific data for Flanders are warranted...
  40. ncbi The effectiveness of cognitive forcing strategies to decrease diagnostic error: an exploratory study
    Jonathan Sherbino
    Division of Emergency Medicine, McMaster University, Hamilton, Ontario, Canada
    Teach Learn Med 23:78-84. 2011
    ..Increasingly, curricula are being implemented in medical training to address this error. Yet there is no experimental evidence that these curricula are effective...
  41. ncbi Evaluation of errors in a clinical laboratory: a one-year experience
    Binita Goswami
    Department of Biochemistry, GB Pant Hospital, New Delhi, India
    Clin Chem Lab Med 48:63-6. 2010
    ..These errors are classified as preanalytical, analytical and postanalytical, depending upon the time of presentation...
  42. pmc Conscious thought beats deliberation without attention in diagnostic decision-making: at least when you are an expert
    Silvia Mamede
    Department of Psychology T13 33, Erasmus University Rotterdam, Burgemeester Oudlaan 50, 3062 PA, Rotterdam, The Netherlands
    Psychol Res 74:586-92. 2010
    ..In contrast, deliberation-without-attention improved novices' decisions, but only in simple problems. Experts benefit from consciously thinking about complex problems; for novices thinking does not help in those cases...
  43. ncbi An estimate of overdiagnosis 15 years after the start of mammographic screening in Florence
    Donella Puliti
    Clinical and Descriptive Epidemiology Unit, ISPO Cancer Prevention and Research Institute, via San Salvi 12, 50135 Florence, Italy
    Eur J Cancer 45:3166-71. 2009
    ..The aim of this study is to evaluate the degree of overdiagnosis of breast cancer 15 years after the introduction of service screening in Florence (Italy)...
  44. ncbi Diagnostic error and clinical reasoning
    Geoffrey R Norman
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Med Educ 44:94-100. 2010
    There is a growing literature on diagnostic errors. The consensus of this literature is that most errors are cognitive and result from the application of one or more cognitive biases...
  45. doi Minimizing diagnostic error: the importance of follow-up and feedback
    Gordon D Schiff
    Division of General Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Am J Med 121:S38-42. 2008
  46. ncbi Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers
    J A Hardie
    Institute of Internal Medicine, Deaconess Hospital, University of Bergen, Norway
    Eur Respir J 20:1117-22. 2002
    ..The criteria used to define the various stages of chronic obstructive pulmonary disease need to be age-specific...
  47. ncbi The frequency and nature of medical error in primary care: understanding the diversity across studies
    John Sandars
    School of Primary Care, University of Manchester, Walmer Street, Manchester M14 5NP, UK
    Fam Pract 20:231-6. 2003
    ..Understanding the frequency and nature of medical error in primary care is a first step in developing a policy to reduce harm and improve patient safety. There has been scant research into this area...
  48. ncbi Digital mammography screening: weighing reduced mortality against increased overdiagnosis
    Rianne De Gelder
    Erasmus MC, Department of Public Health, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
    Prev Med 53:134-40. 2011
    ..Digital mammography has been shown to increase the detection of ductal carcinoma in situ (DCIS) compared to screen-film mammography. The benefits and risks of such an increase were assessed...
  49. doi The vanishing nonforensic autopsy
    Kaveh G Shojania
    University of Ottawa and Ottawa Health Research Institute, Ottawa
    N Engl J Med 358:873-5. 2008
  50. ncbi Factors associated with misdiagnosis of COPD in primary care
    Julia A Walters
    Menzies Research Institute, University of Tasmania, Tasmania, Australia
    Prim Care Respir J 20:396-402. 2011
    ..To assess the misclassification of chronic obstructive pulmonary disease (COPD) in Australian primary care...
  51. pmc Types and origins of diagnostic errors in primary care settings
    Hardeep Singh
    Michael E DeBakey Veterans Affairs Medical Center, and Section of Health Services Research, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
    JAMA Intern Med 173:418-25. 2013
    b>Diagnostic errors are an understudied aspect of ambulatory patient safety.
  52. pmc Managing the pre- and post-analytical phases of the total testing process
    Robert Hawkins
    Department of Laboratory Medicine, Tan Tock Seng Hospital, Tan Tok Seng, Singapore
    Ann Lab Med 32:5-16. 2012
    ....
  53. ncbi Risk management in the preanalytical phase of laboratory testing
    Giuseppe Lippi
    Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
    Clin Chem Lab Med 45:720-7. 2007
    ....
  54. pmc Overdiagnosis in publicly organised mammography screening programmes: systematic review of incidence trends
    Karsten Juhl Jørgensen
    The Nordic Cochrane Centre, Rigshospitalet, Dept 3343, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    BMJ 339:b2587. 2009
    ..To estimate the extent of overdiagnosis (the detection of cancers that will not cause death or symptoms) in publicly organised screening programmes...
  55. ncbi Angioimmunoblastic T-cell lymphoma: clinical and laboratory features at diagnosis in 77 patients
    Florence Lachenal
    Hospices Civils de Lyon, Department of Internal Medicine, Centre Hospitalier Lyon Sud, Pierre Benite, France
    Medicine (Baltimore) 86:282-92. 2007
    ..The current study underlines the diversity of presenting manifestations of angioimmunoblastic T-cell lymphoma...
  56. ncbi Overdiagnosis in breast cancer: design and methods of estimation in observational studies
    Donella Puliti
    Clinical and Descriptive Epidemiology Unit, ISPO, Florence, Italy
    Prev Med 53:131-3. 2011
    ..These estimates vary widely. In this paper we present some of the methodological issues which explain the large variability of the reported findings...
  57. ncbi Why diagnostic errors don't get any respect--and what can be done about them
    Robert M Wachter
    Department of Medicine, University of California, San Francisco, CA, USA
    Health Aff (Millwood) 29:1605-10. 2010
    ..However, diagnostic errors, although common and often serious, have not received comparable attention...
  58. ncbi Diagnostic errors after inferior petrosal sinus sampling
    Brooke Swearingen
    Neuroendocrine Clinical Center, Division of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 89:3752-63. 2004
    ....
  59. ncbi A method of identifying and correcting miscoding, misclassification and misdiagnosis in diabetes: a pilot and validation study of routinely collected data
    S de Lusignan
    St George s University of London, London, UK
    Diabet Med 27:203-9. 2010
    ..The aim of the study was to measure the accuracy of diabetes diagnostic data and explore the scope for identifying errors...
  60. pmc Diagnostic errors in pediatric echocardiography: development of taxonomy and identification of risk factors
    Oscar J Benavidez
    Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    Circulation 117:2995-3001. 2008
    Despite increased interest in complications within pediatric cardiology, the domain of imaging-related diagnostic errors has received little attention...
  61. ncbi "Pre-pre" and "post-post" analytical error: high-incidence patient safety hazards involving the clinical laboratory
    Michael Laposata
    Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Clin Chem Lab Med 45:712-9. 2007
    ....
  62. pmc Overdiagnosis in organised mammography screening in Denmark. A comparative study
    Karsten J Jørgensen
    The Nordic Cochrane Centre, Rigshospitalet, Dept 3343, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    BMC Womens Health 9:36. 2009
    ..We quantified overdiagnosis in the Danish mammography screening programme, which is uniquely suited for this purpose, as only 20% of the Danish population has been offered organised mammography screening over a long time-period...
  63. ncbi Misdiagnosed patients with bipolar disorder: comorbidities, treatment patterns, and direct treatment costs
    Louis S Matza
    The MEDTAP Institute at UBC, 7101 Wisconsin Avenue, Suite 600, Bethesda, MD 20814, USA
    J Clin Psychiatry 66:1432-40. 2005
    ..The purpose of this study was to examine comorbidities, treatment patterns, and direct treatment costs of patients with bipolar disorder who are misdiagnosed with unipolar depression...
  64. ncbi Interference of gadolinium-containing contrast-enhancing agents with colorimetric calcium laboratory testing
    Andrea Löwe
    Invest Radiol 40:521-5. 2005
    ....
  65. ncbi Clinical reasoning: the relative contribution of identification, interpretation and hypothesis errors to misdiagnosis
    Michele Groves
    Faculty of Biological and Chemical Sciences, University of Queensland, St Lucia 4072, Australia
    Med Teach 25:621-5. 2003
    ....
  66. pmc Validation of a diagnostic reminder system in emergency medicine: a multi-centre study
    Padmanabhan Ramnarayan
    Children s Acute Transport Service, London WC1R 4LL, UK
    Emerg Med J 24:619-24. 2007
    ..We evaluated a novel web-based reminder system, which provides rapid diagnostic advice to users based on free text search terms...
  67. ncbi Gadolinium magnetic resonance contrast agents produce analytic interference in multiple serum assays
    Kerry A S Proctor
    Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, USA
    Am J Clin Pathol 121:282-92. 2004
    ..Likewise, certain analytic methods are more prone to interference, while others not affected...
  68. ncbi Clinical and autopsy diagnoses in the intensive care unit: a prospective study
    Alain Combes
    Services de Réanimation Médicale, Hopital Bichat, Assistance Publique Hopitaux de Paris, Paris, France
    Arch Intern Med 164:389-92. 2004
    ..Autopsy rates have declined worldwide, but recent retrospective intensive care unit (ICU) data indicate major discrepancies between more than 25% of clinical and autopsy diagnoses...
  69. ncbi Identification errors involving clinical laboratories: a College of American Pathologists Q-Probes study of patient and specimen identification errors at 120 institutions
    Paul N Valenstein
    Department of Pathology, St Joseph Mercy Hospital, Ann Arbor, Mich 48106 0998, USA
    Arch Pathol Lab Med 130:1106-13. 2006
    ..Misidentified laboratory specimens may cause patient injury, but their frequency in general laboratory practice is unknown...
  70. ncbi Reinterpretation of radiological imaging in patients referred to a tertiary referral centre with a suspected pancreatic or hepatobiliary malignancy: impact on treatment strategy
    Esther H B M Tilleman
    Department of Surgery of the Academic Medical Center Amsterdam, Suite G4 144, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Eur Radiol 13:1095-9. 2003
    ..Additional ultrasound or CT resulted in a change in treatment strategy for 24 patients (30%). Improved communication and reinterpretation of radiological investigations may reduce unnecessary referral...
  71. ncbi Missed breast carcinoma: pitfalls and pearls
    Aneesa S Majid
    Department of Radiology, Medical College of Virginia, Virginia Commonwealth University, 401 N 12th St, Richmond, VA 23298, USA
    Radiographics 23:881-95. 2003
    ....
  72. ncbi RADPEER quality assurance program: a multifacility study of interpretive disagreement rates
    James P Borgstede
    Colorado Springs, CO 80908 3239, USA
    J Am Coll Radiol 1:59-65. 2004
    ....
  73. ncbi Exploring the iceberg of errors in laboratory medicine
    Mario Plebani
    Department of Laboratory Medicine, University Hospital of Padova, Italy
    Clin Chim Acta 404:16-23. 2009
    ..g., inappropriate test request, error in patient identification and/or blood collection). Data on diagnostic errors in primary care and in the emergency department setting demonstrate that inappropriate test requesting and ..
  74. ncbi Malaria overdiagnosis and burden of malaria misdiagnosis in the suburbs of central Sudan: special emphasis on artemisinin-based combination therapy era
    Salwa M E A-Elgayoum
    Faculty of Science, Department of Zoology, University of Khartoum, P O Box 321, Khartoum, Sudan 11111
    Diagn Microbiol Infect Dis 64:20-6. 2009
    ..Finally, different scenarios were suggested for improvement of malaria diagnosis...
  75. ncbi Medical errors: an introduction to concepts
    Jawahar Kalra
    Department of Pathology, College of Medicine, University of Saskatchewan and Royal University Hospital, Saskatoon, Saskatchewan, Canada S7N 0W8
    Clin Biochem 37:1043-51. 2004
    ..The cognitive influence on medical decision-making and error generation is also significant and should not be discounted...
  76. ncbi Death certification errors at an academic institution
    Bobbi S Pritt
    Department of Pathology, College of Medicine, University of Vermont, Burlington, VT, USA
    Arch Pathol Lab Med 129:1476-9. 2005
    ..The correctly completed death certificate provides invaluable personal, epidemiologic, and legal information and should be thorough and accurate. Death certification errors are common and range from minor to severe...
  77. pmc Accuracy of Burkholderia pseudomallei identification using the API 20NE system and a latex agglutination test
    Premjit Amornchai
    Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Clin Microbiol 45:3774-6. 2007
    ..mallei and 98 B. thailandensis isolates were not correctly identified. A latex agglutination test was positive for 796/800 (99.5%) B. pseudomallei isolates and negative for 120 other oxidase-positive gram-negative bacilli...
  78. ncbi Medical errors: impact on clinical laboratories and other critical areas
    Jawahar Kalra
    Department of Pathology, College of Medicine, University of Saskatchewan and Royal University Hospital, Saskatoon, Saskatchewan, Canada
    Clin Biochem 37:1052-62. 2004
    ..Appropriate attention to system factors involved in these errors and designing intelligent system approaches may help control and eliminate many of these errors in health care...
  79. ncbi An evaluation of automated neonatal seizure detection methods
    Stephen Faul
    Department of Electrical and Electronic Engineering, University College Cork, College Road, Cork, Ireland
    Clin Neurophysiol 116:1533-41. 2005
    ..To evaluate 3 published automated algorithms for detecting seizures in neonatal EEG...
  80. ncbi Frequent diagnostic errors in cardiac PET/CT due to misregistration of CT attenuation and emission PET images: a definitive analysis of causes, consequences, and corrections
    K Lance Gould
    The Weatherhead PET Center For Preventing and Reversing Atherosclerosis, University of Texas Medical School and Memorial Hermann Hospital, Houston, Texas 77030, USA
    J Nucl Med 48:1112-21. 2007
    ..Cardiac PET combined with CT is rapidly expanding despite artifactual defects and false-positive results due to misregistration of PET and CT attenuation correction data-the frequency, cause, and correction of which remain undetermined...
  81. pmc Assessment of the potential impact of a reminder system on the reduction of diagnostic errors: a quasi-experimental study
    Padmanabhan Ramnarayan
    Children s Acute Transport Service CATS, 44B Bedford Row, London, WC1H 4LL, UK
    BMC Med Inform Decis Mak 6:22. 2006
    ....
  82. ncbi Artifacts and pitfalls in myocardial perfusion imaging
    Steven Burrell
    Department of Diagnostic Imaging, Queen Elizabeth II Health Sciences Centre, and Dalhousie University, Halifax, Nova Scotia, Canada
    J Nucl Med Technol 34:193-211; quiz 212-4. 2006
    ..The reader should develop an understanding of steps to limit these factors, actions to correct them if they do arise and, when necessary, how to incorporate their influence into the interpretation of the study...
  83. ncbi Pitfalls and artifacts in 18FDG PET and PET/CT oncologic imaging
    Gary J R Cook
    Department of Nuclear Medicine and PET, Royal Marsden Hospital, Sutton, Surrey SM2 5PT, UK
    Semin Nucl Med 34:122-33. 2004
    ..It is essential that we learn these potential pitfalls so that patients can be optimally prepared for their scans and that accurate interpretation can be made...
  84. ncbi Patient record review of the incidence, consequences, and causes of diagnostic adverse events
    Laura Zwaan
    Department of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    Arch Intern Med 170:1015-21. 2010
    b>Diagnostic errors often result in patient harm. Previous studies have shown that there is large variability in results in different medical specialties...
  85. ncbi Inappropriate treatment of catheter-associated asymptomatic bacteriuria in a tertiary care hospital
    Matthew Cope
    Department of Internal Medicine, Duke University, Durham, North Carolina, USA
    Clin Infect Dis 48:1182-8. 2009
    ....
  86. ncbi Changes in rates of autopsy-detected diagnostic errors over time: a systematic review
    Kaveh G Shojania
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    JAMA 289:2849-56. 2003
    ..Substantial discrepanies exist between clinical diagnoses and findings at autopsy. Autopsy may be used as a tool for quality management to analyze diagnostic discrepanies...
  87. pmc Is hospital discharge administrative data an appropriate source of information for cancer registries purposes? Some insights from four Spanish registries
    Enrique E Bernal-Delgado
    Health Services Research Unit, Institute for Health Sciences in Aragon, Zaragoza, Spain
    BMC Health Serv Res 10:9. 2010
    ..The frequency of false positive and false negative cases recommends local validation...
  88. pmc Reducing errors made by emergency physicians in interpreting radiographs: longitudinal study
    J A Espinosa
    Department of Emergency Medicine, Overlook Hospital, Atlantic Health System, 99 Beauvoir Avenue, Summit, NJ 07902, USA
    BMJ 320:737-40. 2000
    ..To reduce errors made in the interpretation of radiographs in an emergency department...
  89. ncbi Dual processing and diagnostic errors
    Geoff Norman
    Department of Clinical Epidemiology and Biostatistics, McMaster University, ON, Canada
    Adv Health Sci Educ Theory Pract 14:37-49. 2009
    In this paper, I review evidence from two theories in psychology relevant to diagnosis and diagnostic errors. "Dual Process" theories of thinking, frequently mentioned with respect to diagnostic error, propose that categorization ..
  90. ncbi Effect of primary-care spirometry on the diagnosis and management of COPD
    P P Walker
    Division of Infection and Immunity, School of Clinical Sciences, University of Liverpool, Liverpool, UK
    Eur Respir J 28:945-52. 2006
    ..The use of bronchodilator reversibility testing in this setting may be important to avoid misdiagnosis...
  91. pmc The frequency of missed test results and associated treatment delays in a highly computerized health system
    Terry L Wahls
    Iowa City Department of Veterans Affairs VA Medical Center, Iowa City, IA, USA
    BMC Fam Pract 8:32. 2007
    b>Diagnostic errors associated with the failure to follow up on abnormal diagnostic studies ("missed results") are a potential cause of treatment delay and a threat to patient safety...
  92. ncbi Diagnosis of unipolar depression following initial identification of bipolar disorder: a common and costly misdiagnosis
    Michael D Stensland
    Eli Lilly and Company, Indianapolis, IN 46285, USA
    J Clin Psychiatry 69:749-58. 2008
    ..Bipolar disorder is challenging to diagnose in medical practice...
  93. ncbi Diagnostic errors and reflective practice in medicine
    Silvia Mamede
    Innovare Institute, Fortaleza, Ceara, Brazil
    J Eval Clin Pract 13:138-45. 2007
    Adverse effects of medical errors have received increasing attention. Diagnostic errors account for a substantial fraction of all medical errors, and strategies for their prevention have been explored...
  94. ncbi [Discrepancies between clinical diagnoses and autopsy findings]
    María Virginia Bürgesser
    Servicio de Patologia, Hospital Privado de Cordoba, Cordoba, Argentina
    Medicina (B Aires) 71:135-8. 2011
    ..We suggest to adopt educational and informative strategies, to revalue the importance of autopsy, and traditional clinical practices...
  95. ncbi Radiology resident interpretations of on-call imaging studies: the incidence of major discrepancies
    Victoria F Cooper
    Department of Radiology, Northwestern University Feinberg School of Medicine, 676 North St Clair Street, Suite 800, Chicago, IL 60611, USA
    Acad Radiol 15:1198-204. 2008
    ..To determine the incidence of radiology resident preliminary interpretation errors for plain film, body computed tomography, and neuroradiology (neuro)computed tomographic examinations read on call...
  96. ncbi Twelve tips for teaching avoidance of diagnostic errors
    Robert L Trowbridge
    Maine Medical Center, Portland, Maine 04102, USA ME 04102 USA
    Med Teach 30:496-500. 2008
    ..Most medical students and physician trainees receive little instruction regarding both the root causes of diagnostic errors and how to avoid such errors.
  97. ncbi Diagnostic errors in polytrauma: a structured review of the recent literature
    Luana Stanescu
    Department of Radiology, Harborview Medical Center, University of Washington, 325 Ninth Avenue, Box 359728, Seattle, 98104 2499, USA
    Emerg Radiol 12:119-23. 2006
    Clinically important diagnostic errors are relatively common among polytrauma patients (2-40%)...
  98. ncbi Unnecessary extractions in patients with hemicrania continua: case reports and implication for dentistry
    Sanjay Prakash
    Department of Neurology, Medical College, Baroda, Gujarat, India
    J Orofac Pain 24:408-11. 2010
    ..The findings suggest that initial treatment with drugs specific for primary headache disorders should be instituted before subjecting patients to invasive procedures...
  99. ncbi Soft-tissue sarcomas in the inguinal region may present as deep vein thrombosis
    Makoto Emori
    Musculoskeletal Oncology Service, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
    Ann Vasc Surg 24:951.e7-951.e11. 2010
    ....
  100. ncbi Preliminary radiology resident interpretations versus final attending radiologist interpretations and the impact on patient care in a community hospital
    Richard B Ruchman
    Department of Radiology, Monmouth Medical Center, 300 Second Ave, Long Branch, NJ 07740, USA
    AJR Am J Roentgenol 189:523-6. 2007
    ..The objective of our study was to determine the rate of discrepancies between the two interpretations and the possible effect, if any, on patient care...
  101. ncbi End-user errors in applying two malaria rapid diagnostic tests in a remote area of Sudan
    Osama M E Seidahmed
    National Malaria Control Program, Khartoum, Sudan
    Trop Med Int Health 13:406-9. 2008
    ..End-user errors were more frequent with OptiMAL IT than Core Pf tests. To improve malaria diagnosis with rapid tests, users require training and better manufacturer's instructions that take into account local conditions...

Research Grants65

  1. Reducing Harm to Patients from Diagnostic Errors
    ETA BERNER; Fiscal Year: 2007
    ..results and developing a research and education agenda in the area of reducing harm to patients from diagnostic errors. Diagnostic errors are increasingly recognized as a serious contributor to downstream patient safety ..
  2. A Multiyear Grant to Support the Diagnostic Error in Medicine (DEM) Annual Confer
    David E Newman-Toker; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Diagnostic errors account for a significant portion of all medical errors and are responsible for substantial harm and avoidable healthcare costs, yet they have not received the attention that other ..
  3. Digital Pathology_Accuracy Viewing Behavior and Image Characterization
    DONALD LEE WEAVER; Fiscal Year: 2013
    ..b>Diagnostic errors are alarmingly frequent and likely lead to altered patient treatment, especially at the thresholds of ..
  4. Improving Pediatric Developmental Screening and Communication: A CME
    Lisa D Marceau; Fiscal Year: 2013
    ..Young Children at Risk for Mental Retardation;and AHRQ has issued a Special Emphasis Notice for research on diagnostic errors (including delay in diagnosis) in the ambulatory care setting...
  5. A Study of Narrative as the Cognitivie Process Underlying Diagnostic Reasoning
    CURTIS SCOTT SMITH; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Physicians commonly commit diagnostic errors. Research demonstrates that these are the most dangerous types of medical errors...
  6. Accuracy of Breast Pathology and the Impact of Double Reading
    DONALD LEE WEAVER; Fiscal Year: 2013
    ..emphasizing the classification of ADH and DCIS, where previous studies reveal a concerning degree of diagnostic errors. This large multi- center study of community pathologists addresses a topic that has growing clinical ..
  7. Accuracy in the Diagnosis of Melanoma &the Impact of Double Reading
    Joann G Elmore; Fiscal Year: 2013
    ..We will evaluate the extent of these diagnostic errors, their sources, and their impact on the U.S. population...
  8. Effects of Attending Surgeon and Obstetrician Fatigue on Operating Room Safety
    Charles A Czeisler; Fiscal Year: 2012
    ..working recurrent 24-hour shifts made 36% more serious medical errors and five times as many serious diagnostic errors as those whose scheduled work is limited to 16 consecutive hours...
  9. Improving Management of Test Results that Return After Hospital Discharge.
    MARTIN CHIENG WERE; Fiscal Year: 2012
    ..form the basis for a large randomized trial to evaluate the impact of the two health-IT interventions on diagnostic errors and on patient outcomes. 7...
  10. Diagnostic Error in Medicine Annual Conference
    Hardeep Singh; Fiscal Year: 2013
    ..b>Diagnostic errors (defined as missed, delayed, or wrong diagnosis) are an important, common, and costly problem but have been ..
  11. Improving the Safety and Quality of Pediatric Health Care
    Eric J Thomas; Fiscal Year: 2013
    ..In addional, research wil be conducted on diagnostic errors, improving compliance with isolation of children with contagious diseases, developing quality measures for ..
  12. Compromised Diagnostic Radiology Interpretation from Observer Fatigue
    Elizabeth A Krupinski; Fiscal Year: 2013
    ..The long-term goal is to reduce diagnostic errors by studying an obvious but serious problem, fatigue, to determine whether it is indeed a root cause of error...
  13. Reducing Errors in the Diagnosis of Melanoma using an Intelligent Tutoring System
    DANA GRZYBICKI; Fiscal Year: 2007
    ..g. medication) errors rather than on diagnostic errors. The diagnostic error rate in general surgical pathology is generally accepted to be approximately 1 %, ..
  14. Building a New Model for Diagnosis of ED Dizzy Patients
    David Newman Toker; Fiscal Year: 2007
    ..This research project and the research paradigms derived from it will form the nucleus of a career devoted to research in medical decision-making, causes of diagnostic errors, and methods to preventthem.
  15. Conference: Diagnostic Error in Medicine
    Mark Graber; Fiscal Year: 2009
    ..b>Diagnostic errors comprise a significant fraction of medical errors and are responsible for substantial harm and avoidable ..
  16. Improving Patient Safety by Examining Pathology Errors
    Stephen Raab; Fiscal Year: 2006
    ..A paucity of information exists on anatomic pathology diagnostic errors and their effect on patient outcomes...
  17. AN EXPERT SYSTEM AS A SCREEN FOR QUALITY OF CARE
    LEE LAU; Fiscal Year: 1991
    We propose an experiment to evaluate the use of an expert system (Iliad) to detect diagnostic errors that may lead to significant quality problems...
  18. ECTODERMAL DYSPLASIAS A MOLECULAR GENETIC ANALYSIS
    Jonathan Zonana; Fiscal Year: 1993
    ..indistinguishable autosomal recessive form of the disorder, which if unrecognized could cause serious diagnostic errors. In addition, a large number of unrelated males will be screened, initially with anonymous DNA probes, but ..
  19. Implications of OAE Cochlear Source Contribution
    Tiffany Johnson; Fiscal Year: 2006
    ..4) The role of fine structure (thought to arise from the complex summation of distortion- and reflection-source energy for DPOAEs) in prediction and diagnostic errors will be evaluated.
  20. COMPUTER-BASED EXPERT SYSTEM FOR CERVICAL CYTOLOGY
    GEORGE WIED; Fiscal Year: 1991
    ..The diagnostic software and its built-in quality control may reduce diagnostic errors and prevent overtreatment of patients; both are problems especially in the operation of laboratories with ..
  21. MIPS XII Conference
    Elizabeth Krupinski; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  22. Using Electronic Records to Detect and Learn from Ambulatory Diagnostic Errors
    Eric Thomas; Fiscal Year: 2008
    ..The overall goal of the application is to utilize data from electronic health records (EHR) to detect diagnostic errors in primary care, understand their causes, and lay groundwork to formulate future prevention strategies...
  23. Optimized Compression for Telepathology Virtual Slides
    Elizabeth Krupinski; Fiscal Year: 2009
    ....
  24. Medical Image Perception Society Confrence XI
    Elizabeth Krupinski; Fiscal Year: 2005
    ..abstract_text> ..
  25. OPTIMIZING SOFTCOPY DISPLAYS FOR DIGITAL MAMMOGRAPHY
    Elizabeth Krupinski; Fiscal Year: 2002
    ..The JND metrix model will then be used to systematically explore and optimize CRT design tradeoffs for current and future digital-mammography display systems. ..
  26. Conference--Medical Image Perception
    Elizabeth Krupinski; Fiscal Year: 2003
    ..This grant will be used to provide financial support for about 12 graduate students and residents, as well as logistic support for publicity and program printing. ..
  27. OPTIMIZING SOFTCOPY DISPLAYS FOR DIGITAL MAMMOGRAPHY
    Elizabeth Krupinski; Fiscal Year: 2003
    ..The JND metrix model will then be used to systematically explore and optimize CRT design tradeoffs for current and future digital-mammography display systems. ..
  28. RISK FACTORS AS PREDICTORS OF ECTOPIC PREGNANCY
    Kurt T Barnhart; Fiscal Year: 2010
    ....
  29. NLAAS II: Unraveling Differences for Clinical Services
    Margarita Alegria; Fiscal Year: 2008
    ....
  30. Obstacles to Answering Physicians' Patient-Care Question
    John Ely; Fiscal Year: 2003
    ..Benefit: By identifying areas where knowledge resources fail to meet the needs of physicians, we will provide recommendations to help knowledge base developers better meet those needs. ..
  31. HORMONE REPLACEMENT THERAPY AND BREAST CANCER
    Patricia Carney; Fiscal Year: 2004
    ..abstract_text> ..
  32. Mechanism Underlying the Effects of Blue Light in Humans
    STEVEN LOCKLEY; Fiscal Year: 2007
    ..abstract_text> ..
  33. Bipolar Disorder in Pregnancy: Predictors of Morbidity
    DONALD NEWPORT; Fiscal Year: 2009
    ..Furthermore, the novel PK data will expand our understanding of prenatal drug metabolism, and the project will establish a cohort of children of women with BPD with detailed prospective prenatal histories. ..
  34. COMPUTER-AIDED DIAGNOSIS IN DIGITAL MAMMOGRAPHY
    Robert Nishikawa; Fiscal Year: 2001
    ..Using this information, the applicants proposed to develop an interface between the detection and classification schemes; and (5) To perform a preliminary clinical evaluation of the classification scheme. ..
  35. Extended Release Mixed Amphetamine Salts for Adult ADHD and Cocaine Dependence
    Frances Rudnick Levin; Fiscal Year: 2010
    ..Here a nearly unique opportunity exists to treat two conditions, ADHD and cocaine dependence, with a single medication, hopefully leading to improved treated outcome in this difficult-to-treat population. ..
  36. Marijuana Abusing ADHD Teens: Atomoxetine Treatment
    Frances Levin; Fiscal Year: 2004
    ..4. To examine the relationship between medication treatment, reduction in ADHD symptoms, and improvement in retention and/or progress in treatment using mediational analyses. ..
  37. Computational Methods for Personalized and Adaptive Cognitive Training
    Rebecca S Crowley; Fiscal Year: 2010
    ..Work in these areas has the potential to deeply impact the fields of patient safety, medical simulation and competency- based assessment, in addition to guiding the development of future medical training systems. ..
  38. Human Subjects Research Enhancements Programs
    William Rosner; Fiscal Year: 2002
    ..All such monthly reviews and quizzes will be archived for review. All of the above activities will be designed to be continued after the completion of the initial year of support. ..
  39. EVALUATING USE OF GENETIC INFORMATION: A MODEL PROCESS
    Wylie Burke; Fiscal Year: 2003
    ..5. To conduct an evaluation of the model process within a large health care system. ..
  40. Hormones and Erectile Dysfunction in Aging Men
    John McKinlay; Fiscal Year: 2004
    ....
  41. Symposium on Pediatric Neurotransmitter Disease
    K Michael Gibson; Fiscal Year: 2002
    ..The perspectives of parents of affected children wilI be an important component of this conference. ..
  42. TRIAL OF ACUPUNCTURE FOR CARPAL TUNNEL SYNDROME
    Arthur Weinstein; Fiscal Year: 2001
    ..abstract_text> ..
  43. PROSTATIC STEROIDS AND SECOND MESSENGERS
    William Rosner; Fiscal Year: 2001
    ....
  44. Treatment and/or Prevention of Urinary Tract Infections
    BARBARA TRAUTNER; Fiscal Year: 2008
    ..An agent to prevent and treat UTI that does not encourage microbial resistance would have a significant impact on public health. [unreadable] [unreadable] [unreadable]..
  45. E. coli for prevention of Catheter UTI in SCI Patients
    BARBARA TRAUTNER; Fiscal Year: 2006
    ..The candidate plans to combine her clinical background in infectious diseases with the mentored research preformed under this award in order to reduce the secondary infectious complications of mobility disorders. ..
  46. Oral Chemotherapy Safety in Ambulatory Oncology: A Proactive Risk Assessment
    SAUL WEINGART; Fiscal Year: 2007
    ..Lessons about oral chemotherapy safety are applicable to other high-alert medications in ambulatory care. [unreadable] [unreadable] [unreadable]..
  47. Cognitive Basis of CHD Disparities: Factorial Experiment
    John McKinlay; Fiscal Year: 2008
    ..abstract_text> ..
  48. Role of IGFBP -3 in mediating p53-induced apoptosis
    Adda Grimberg; Fiscal Year: 2006
    ..These studies also reflect Dr. Grimberg?s long-term career goals of exploring the interrelatedness of endocrine and oncologic molecular biology principles and applying them to clinical problems of dysregulated growth. ..
  49. Activity-dependent signaling in aging skeletal muscle
    Roger Fielding; Fiscal Year: 2006
    ....
  50. Medical Management of Pediatric Neurotransmitter Disorders- A Multidisciplinary
    K Michael Gibson; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  51. Trajectories of Urologic Disease: Follow-up of BACH
    John McKinlay; Fiscal Year: 2007
    ....
  52. Third International Neural Engineering Conference 2007
    Metin Akay; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  53. Coping and Social Comparison in Elderly Cardiac Patients
    Jerry Suls; Fiscal Year: 2006
    ..Although the present research focuses on adaptation to cardiac disease, results should also be relevant and exportable to older adults that are coping with other chronic illnesses. ..
  54. Assessment of Personality Disorders in Older Adults
    Steve Balsis; Fiscal Year: 2007
    ..The findings from these studies hopefully will lead to better assessment criteria for adults and further understanding of how personality pathology manifests itself in older adults. ..
  55. Combined Pharmacotherapies for Cocaine Dependence
    Frances Levin; Fiscal Year: 2008
    ..3. To explore a set of related secondary outcomes (treatment retention, global functioning, and HIV risk behavior) as well as moderators and mediators potentially reflective of mechanism of action. [unreadable] [unreadable] [unreadable]..
  56. Clinical Decisions with Older Patients: 3rd Experiment
    John McKinlay; Fiscal Year: 2006
    ..The most recent issue of AJPH (February 2003) highlights the urgent need for comparative analyses of different health systems in order to provide policy lessons for the rapidly changing US health care system. ..
  57. COMT Genotype and Risky Decision Making in HIV and Methamphetamine Dependence
    Mariana Cherner; Fiscal Year: 2010
    ..Findings will add to the understanding of individual differences in response to risk-reduction interventions and have the potential to inform the tailoring of future interventions. ..
  58. The ODIE Toolkit - Software for Information Extraction and Biomedical Ontology De
    Rebecca S Crowley; Fiscal Year: 2010
    ..Additionally, the project would contribute to the software for developing other applications by helping researchers build more comprehensive ontologies. The results of this work may benefit both medical research and patient care. ..
  59. Pretest Probability Assessment for Pulmonary Embolism
    JEFFREY KLINE; Fiscal Year: 2005
    ..In phase III, we will test the validity of the PE PREtest Consult TM and determine if the use of the PE PREtest ConsultTM will decrease unnecessary testing for PE. ..
  60. Clinical Investigation of E.coli Biofilm Formation in the Human Bladder
    BARBARA TRAUTNER; Fiscal Year: 2007
    ..No effective strategy exists to prevent CAUTI in persons who require ongoing catheter use. Identifying genes that are required to cause CAUTI will lead to new strategies to prevent this illness. [unreadable] [unreadable] [unreadable]..
  61. Center effects influence on anemia and mortality
    Jeffrey Fink; Fiscal Year: 2005
    ..abstract_text> ..
  62. Effect of practice guidelines on care of chronic kidney disease in the VHA
    Jeffrey Fink; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  63. An Evaluation of Modulators That Influence Visual Search Accuracy
    MATHIAS FLECK; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  64. Treating PTSD in Children Exposed to Domestic Violence
    Judith Cohen; Fiscal Year: 2008
    ..abstract_text> ..
  65. Pharmacologic Treat. of PTSD in Sexually Abused Children
    Judith Cohen; Fiscal Year: 2005
    ....