computer assisted radiographic image interpretation

Summary

Summary: Computer systems or networks designed to provide radiographic interpretive information.

Top Publications

  1. ncbi Evaluation of deformable registration of patient lung 4DCT with subanatomical region segmentations
    Ziji Wu
    Department of Radiation Oncology, Massachusetts General Hospital, 55 Fruit Street, Boston, Massachusetts 02114, USA
    Med Phys 35:775-81. 2008
  2. ncbi Computer recognition of regional lung disease patterns
    R Uppaluri
    Department of Electrical and Computer Engineering and Radiology, Divison of Pulmonary, Department of Internal Medicine, The University of Iowa, Iowa City, Iowa, USA
    Am J Respir Crit Care Med 160:648-54. 1999
  3. ncbi Colorectal cancer: texture analysis of portal phase hepatic CT images as a potential marker of survival
    Kenneth A Miles
    Division of Clinical and Laboratory Sciences, Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, United Kingdom
    Radiology 250:444-52. 2009
  4. ncbi Patient-specific models for lung nodule detection and surveillance in CT images
    M S Brown
    Department of Radiological Sciences, University of California, Los Angeles 90095, USA
    IEEE Trans Med Imaging 20:1242-50. 2001
  5. pmc Analysis of deformable image registration accuracy using computational modeling
    Hualiang Zhong
    Department of Radiation Oncology, Henry Ford Health System, Detroit, Michigan 48202, USA
    Med Phys 37:970-9. 2010
  6. ncbi Low-dose megavoltage cone-beam CT for radiation therapy
    Jean Pouliot
    Department of Radiation Oncology, University of California San Francisco, CA 94143 1708, USA
    Int J Radiat Oncol Biol Phys 61:552-60. 2005
  7. ncbi Automatic lung segmentation for accurate quantitation of volumetric X-ray CT images
    S Hu
    Department of Biomedical Engineering, University of Iowa, Iowa City 52242, USA
    IEEE Trans Med Imaging 20:490-8. 2001
  8. ncbi Computer-aided detection with screening mammography in a university hospital setting
    Robyn L Birdwell
    Department of Radiology, S092, Stanford University Medical Center, 300 Pasteur Dr, Stanford, CA 94305 5105, USA
    Radiology 236:451-7. 2005
  9. ncbi Initial evaluation of coronary images from 320-detector row computed tomography
    Frank J Rybicki
    Noninvasive Cardiovascular Imaging, Brigham and Women s Hospital, Boston, MA 02115, USA
    Int J Cardiovasc Imaging 24:535-46. 2008
  10. ncbi Novel use of single X-ray absorptiometry for measuring breast density
    John A Shepherd
    Musuloskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, CA 94143, USA
    Technol Cancer Res Treat 4:173-82. 2005

Research Grants

  1. Computerized Analysis of Mesothelioma on CT Scans
    Samuel Armato; Fiscal Year: 2009
  2. 3D Massive Training ANN for CAD for Colon Cancer in CT Colonography
    Kenji Suzuki; Fiscal Year: 2010
  3. COMPUTER AIDED DIAGNOSIS IN CT OF THE THORAX
    Samuel Armato; Fiscal Year: 2004
  4. Standard Database for CT Lung Images
    Samuel Armato; Fiscal Year: 2006
  5. Monochromatic Phase-Contrast Breast Cancer Radiography
    Edwin Donnelly; Fiscal Year: 2005
  6. Phase Contrast Computed Tomography Scanner
    Edwin Donnelly; Fiscal Year: 2007
  7. ROC Analysis of Imaging System Evaluations
    David Gur; Fiscal Year: 2002
  8. Interactive CAD for Mammography
    Bin Zheng; Fiscal Year: 2007
  9. Assessment of Variance Structure in ROC Studies
    David Gur; Fiscal Year: 2006
  10. DETECTION AND LOCALIZATION IN MAMMOGRAPHY
    Bin Zheng; Fiscal Year: 2002

Detail Information

Publications264 found, 100 shown here

  1. ncbi Evaluation of deformable registration of patient lung 4DCT with subanatomical region segmentations
    Ziji Wu
    Department of Radiation Oncology, Massachusetts General Hospital, 55 Fruit Street, Boston, Massachusetts 02114, USA
    Med Phys 35:775-81. 2008
    ..Statistical analyses of the mismatch of the homologous points before and after registration demonstrated improved overall accuracy for both algorithms...
  2. ncbi Computer recognition of regional lung disease patterns
    R Uppaluri
    Department of Electrical and Computer Engineering and Radiology, Divison of Pulmonary, Department of Internal Medicine, The University of Iowa, Iowa City, Iowa, USA
    Am J Respir Crit Care Med 160:648-54. 1999
    ..62. For regional tissue characterization, the AMFM is 100% reproducible and performs as well as experienced human observers who have been told the patient diagnosis...
  3. ncbi Colorectal cancer: texture analysis of portal phase hepatic CT images as a potential marker of survival
    Kenneth A Miles
    Division of Clinical and Laboratory Sciences, Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, United Kingdom
    Radiology 250:444-52. 2009
    ....
  4. ncbi Patient-specific models for lung nodule detection and surveillance in CT images
    M S Brown
    Department of Radiological Sciences, University of California, Los Angeles 90095, USA
    IEEE Trans Med Imaging 20:1242-50. 2001
    ..The system automatically detected 16 out of a possible 20 (80%) of new nodules on follow-up scans with ten FPs per case...
  5. pmc Analysis of deformable image registration accuracy using computational modeling
    Hualiang Zhong
    Department of Radiation Oncology, Henry Ford Health System, Detroit, Michigan 48202, USA
    Med Phys 37:970-9. 2010
    ....
  6. ncbi Low-dose megavoltage cone-beam CT for radiation therapy
    Jean Pouliot
    Department of Radiation Oncology, University of California San Francisco, CA 94143 1708, USA
    Int J Radiat Oncol Biol Phys 61:552-60. 2005
    ....
  7. ncbi Automatic lung segmentation for accurate quantitation of volumetric X-ray CT images
    S Hu
    Department of Biomedical Engineering, University of Iowa, Iowa City 52242, USA
    IEEE Trans Med Imaging 20:490-8. 2001
    ..8 pixels (0.54 mm). The mean intrasubject change in tissue content over the three scans was 2.75% +/- 2.29% (mean +/- standard deviation)...
  8. ncbi Computer-aided detection with screening mammography in a university hospital setting
    Robyn L Birdwell
    Department of Radiology, S092, Stanford University Medical Center, 300 Pasteur Dr, Stanford, CA 94305 5105, USA
    Radiology 236:451-7. 2005
    ..To prospectively assess the effect of computer-aided detection (CAD) on screening mammogram interpretation in an academic medical center to determine if the outcome is different than that previously reported for community practices...
  9. ncbi Initial evaluation of coronary images from 320-detector row computed tomography
    Frank J Rybicki
    Noninvasive Cardiovascular Imaging, Brigham and Women s Hospital, Boston, MA 02115, USA
    Int J Cardiovasc Imaging 24:535-46. 2008
    ..Patient dose is estimated for prospective and retrospective ECG-gating; initial correlation between 320-slice CT and coronary catheterization is illustrated...
  10. ncbi Novel use of single X-ray absorptiometry for measuring breast density
    John A Shepherd
    Musuloskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, CA 94143, USA
    Technol Cancer Res Treat 4:173-82. 2005
    ..Using phantoms, BD(SXA) has been shown to have a long-term repeatability of better than 2% for a breast composition range of 0 to 100% fibroglandular density...
  11. ncbi Computer-aided detection for screening mammography
    Susan M Astley
    University of Manchester, Imaging Science and Biomedical Engineering, Stopford Building, Oxford Road, Manchester M13 9PT, UK
    Acad Radiol 11:1139-43. 2004
    ..This article is a brief review of CAD for screening mammography; it highlights both the strengths and the weaknesses of the approach, and describes some of the methodologies used to evaluate CAD in a clinical setting...
  12. pmc Validation of CT dose-reduction simulation
    Parinaz Massoumzadeh
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 South Kingshighway, St Louis, Missouri 63110, USA
    Med Phys 36:174-89. 2009
    ..The methodology promises to be a useful tool for researchers and radiologists to explore dose reduction protocols in an effort to produce diagnostic images with radiation dose "as low as reasonably achievable"...
  13. ncbi Impact of breast density on computer-aided detection for breast cancer
    Rachel F Brem
    Department of Radiology, The George Washington University, 2150 Pennsylvania Ave NW, Washington, DC 21117, USA
    AJR Am J Roentgenol 184:439-44. 2005
    ..Our aim was to determine whether breast density affects the performance of a computer-aided detection (CAD) system for the detection of breast cancer...
  14. ncbi Visual search of mammographic images: influence of lesion subtlety
    Elizabeth A Krupinski
    Department of Radiology, University of Arizona, Tucson, 85724, USA
    Acad Radiol 12:965-9. 2005
    ..The goal of this study is to determine whether mammographic lesion subtlety influences the detection accuracy and visual search parameters of radiologists...
  15. ncbi A calibration approach to glandular tissue composition estimation in digital mammography
    J Kaufhold
    General Electric Global Research Center, Niskayuna, New York 12309, USA
    Med Phys 29:1867-80. 2002
    ..The error in composition due to the quantum noise, which is the limiting noise source in the system, is shown to be less than 1% glandular for most breasts...
  16. ncbi Low-dose CT coronary angiography in the step-and-shoot mode: diagnostic performance
    H Scheffel
    Institute of Diagnostic Radiology, University Hospital Zurich, Raemistr 100, 8091 Zurich, Switzerland
    Heart 94:1132-7. 2008
    ....
  17. ncbi Prospective versus retrospective ECG-gated 64-detector coronary CT angiography: assessment of image quality, stenosis, and radiation dose
    Nobuhiko Hirai
    Department of Clinical Radiology, Hiroshima University Hospital, Hiroshima, Japan
    Radiology 248:424-30. 2008
    ....
  18. ncbi Reproducibility--an important factor determining the quality of computer-aided detection (CAD) systems
    A Malich
    Institute of Diagnostic and Interventional Radiology, Friedrich Schiller University Jena, Bachstrasse 18, 07740 Jena, Germany
    Eur J Radiol 36:170-4. 2000
    ..To test the reproducibility of markings on mammography films set by a commercial computer aided detection (CAD) system...
  19. ncbi Noninvasive coronary angiography with 64-section CT: effect of average heart rate and heart rate variability on image quality
    Sebastian Leschka
    Institute of Diagnostic Radiology, the Clinic for Cardiovascular Surgery, and the Cardiovascular Center, University Hospital Zurich, Raemistrasse 100, CH 8091 Zurich, Switzerland
    Radiology 241:378-85. 2006
    ..To evaluate prospectively the effect of average heart rate and heart rate variability on image quality at 64-section computed tomographic (CT) coronary angiography...
  20. ncbi Computer analysis of computed tomography scans of the lung: a survey
    Ingrid Sluimer
    Image Sciences Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 25:385-405. 2006
    ..In addition, research trends and challenges are identified and directions for future research are discussed...
  21. ncbi Automated detection of lung nodules in CT scans: effect of image reconstruction algorithm
    Samuel G Armato
    Department of Radiology, The University of Chicago, 5841 South Maryland Avenue, Chicago, Illinois 60637, USA
    Med Phys 30:461-72. 2003
    ..When applied to the databases in this manner, the automated method demonstrated overall a similar level of performance, indicating an encouraging degree of robustness...
  22. ncbi Influence of heart rate and temporal resolution on left-ventricular volumes in cardiac multislice spiral computed tomography: a phantom study
    Andreas H Mahnken
    Department of Diagnostic Radiology, RWTH Aachen University, Germany
    Invest Radiol 41:429-35. 2006
    ..We sought to investigate the influence of heart rate and temporal resolution on the assessment of left-ventricular (LV) function with multislice spiral computed tomography (CT)...
  23. ncbi Computer-aided diagnosis and the evaluation of lung disease
    Jane P Ko
    Division of Thoracic Imaging, Department of Radiology, New York University Medical Center, New York, NY 10016, USA
    J Thorac Imaging 19:136-55. 2004
  24. ncbi Accuracy of finite element model-based multi-organ deformable image registration
    K K Brock
    Radiation Medicine Program, Princess Margaret Hospital, University Health Network, 610 University Avenue, Toronto, Ontario, Canada M5G 2M9
    Med Phys 32:1647-59. 2005
    ....
  25. ncbi Use of computer-aided detection (CAD) tools in screening mammography: a multidisciplinary investigation
    E Alberdi
    Centre for Software Reliability and Psychology Department, City University, Northampton Square, London EC1V 0HB
    Br J Radiol 78:S31-40. 2005
    ..We integrate insights from the different pieces of evidence and highlight their implications for the design, evaluation and deployment of this sort of computer tool...
  26. ncbi Quantitative assessment of breast density from digitized mammograms into Tabar's patterns
    N Jamal
    Medical Technology Division, Malaysian Institute for Nuclear Technology Research MINT 43000 Kajang, Malaysia
    Phys Med Biol 51:5843-57. 2006
    ..The technique may be useful as a supplement to the radiologist's assessment in classifying mammograms into Tabar's pattern associated with breast cancer risk...
  27. ncbi Application of the noise power spectrum in modern diagnostic MDCT: part I. Measurement of noise power spectra and noise equivalent quanta
    K L Boedeker
    University of California, Los Angeles, USA
    Phys Med Biol 52:4027-46. 2007
    ..NPS and NEQ under a variety of conditions are examined. Extensions of NPS and NEQ to uses in protocol standardization are also discussed...
  28. ncbi Multi-detector row CT of left ventricular function with dedicated analysis software versus MR imaging: initial experience
    Kai Uwe Juergens
    Department of Clinical Radiology, University of Muenster, Albert Schweitzer Strasse 33, D 48149 Muenster, Germany
    Radiology 230:403-10. 2004
    ....
  29. ncbi Computer-aided classification of interstitial lung diseases via MDCT: 3D adaptive multiple feature method (3D AMFM)
    Ye Xu
    Department of Radiology, University of Iowa, CC701, General Hospital, Iowa City, IA 52242, USA
    Acad Radiol 13:969-78. 2006
    ..In this project, we have further developed a computer-aided detection tool, the adaptive multiple feature method (AMFM), for the detection of interstitial lung diseases based on MDCT-generated volumetric data...
  30. ncbi Performance testing of several classifiers for differentiating obstructive lung diseases based on texture analysis at high-resolution computerized tomography (HRCT)
    YoungJoo Lee
    Department of Industrial Engineering, Seoul National University, Seoul 151 742, Republic of Korea
    Comput Methods Programs Biomed 93:206-15. 2009
    ..05). The naïve Bayesian method performed significantly worse than the other classifiers (t-test, p<0.05). SVM showed the best performance for classification of the obstructive lung diseases in this study...
  31. ncbi Texture-based quantification of pulmonary emphysema on high-resolution computed tomography: comparison with density-based quantification and correlation with pulmonary function test
    Yang Shin Park
    Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Invest Radiol 43:395-402. 2008
    ..To develop a system for texture-based quantification of emphysema on high-resolution computed tomography (HRCT) and to compare it with density-based quantification in correlation with pulmonary function test (PFT)...
  32. ncbi CAD for mammography: the technique, results, current role and further developments
    Ansgar Malich
    Institute of Diagnostic Radiology, Suedharz Krankenhaus Nordhausen, R Koch Str 39, 99374, Nordhausen, Germany
    Eur Radiol 16:1449-60. 2006
    ....
  33. ncbi Evaluation of an automated deformable image matching method for quantifying lung motion in respiration-correlated CT images
    A Pevsner
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Med Phys 33:369-76. 2006
    ..This method has therefore the potential for predicting and quantifying respiration-induced tumor motion in the lung...
  34. pmc Development of an automatic classification system for differentiation of obstructive lung disease using HRCT
    Namkug Kim
    Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 388 1, Pungnap2 Dong, Songpa Gu, Seoul, 138 736, Republic of Korea
    J Digit Imaging 22:136-48. 2009
    ..In addition, the shape features contribute more to overall sensitivity in smaller ROI...
  35. ncbi Dual-source CT with improved temporal resolution in assessment of left ventricular function: a pilot study
    Harald Brodoefel
    Department of Diagnostic Radiology, Eberhard Karls University, Hoppe Seyler Str 3, 72076 Tubingen, Germany
    AJR Am J Roentgenol 189:1064-70. 2007
    ....
  36. ncbi Bone strength at the distal radius can be estimated from high-resolution peripheral quantitative computed tomography and the finite element method
    Joshua A MacNeil
    Department of Mechanical and Manufacturing Engineering, Schulich School of Engineering, University of Calgary, Calgary, Canada
    Bone 42:1203-13. 2008
    ....
  37. ncbi Automated 3-D PDM construction from segmented images using deformable models
    Michael R Kaus
    Philips Research Laboratories, Sector Technical Systems, Hamburg, Germany
    IEEE Trans Med Imaging 22:1005-13. 2003
    ..The adaptation is based on a novel deformable model technique. We illustrate our approach using computed tomography data of the vertebra and the femur. We demonstrate that our method accurately represents and predicts shapes...
  38. pmc Quantifying the accuracy of automated structure segmentation in 4D CT images using a deformable image registration algorithm
    Krishni Wijesooriya
    Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia 23284, USA
    Med Phys 35:1251-60. 2008
    ..Careful assessment of the performance of automatic algorithms is needed in the presence of 4D CT artifacts...
  39. pmc Effect of breast density on computer aided detection
    Ansgar Malich
    Institute of Diagnostic and Interventional Radiology, Friedrich Schiller University Jena, Bachstr 18, 7740 Jena, Germany
    J Digit Imaging 18:227-33. 2005
    ....
  40. ncbi Coronary artery calcium: a multi-institutional, multimanufacturer international standard for quantification at cardiac CT
    Cynthia H McCollough
    Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Radiology 243:527-38. 2007
    ..To develop a consensus standard for quantification of coronary artery calcium (CAC)...
  41. ncbi A local adaptive threshold strategy for high resolution peripheral quantitative computed tomography of trabecular bone
    Andrew J Burghardt
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, CA 94158, USA
    Ann Biomed Eng 35:1678-86. 2007
    ....
  42. ncbi Automated contour mapping using sparse volume sampling for 4D radiation therapy
    Ming Chao
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305 5847, USA
    Med Phys 34:4023-9. 2007
    ..The robustness and accuracy of this approach make it a valuable tool for the efficient use of the available spatial-tempo information for 4D simulation and treatment...
  43. ncbi How extensive of a 4D dataset is needed to estimate cumulative dose distribution plan evaluation metrics in conformal lung therapy?
    Mihaela Rosu
    The University of Michigan, Department of Radiation Oncology, Ann Arbor Michigan 48109 0010, USA
    Med Phys 34:233-45. 2007
    ....
  44. ncbi MDCT angiography for detection and quantification of small intracranial arteries: comparison with conventional catheter angiography
    J Pablo Villablanca
    Department of Radiological Sciences, David Geffen School of Medicine at the University of California, Los Angeles, 10833 Le Conte Ave, Rm B3 115 CHS, Los Angeles, CA 90095 1721, USA
    AJR Am J Roentgenol 188:593-602. 2007
    ..Our goal was to achieve a better understanding of the capabilities and limitations of both MDCT angiography and digital subtraction angiography in the evaluation of intracranial arteries with an average diameter of 1.5 mm or less...
  45. ncbi Multi-detector row CT attenuation measurements: assessment of intra- and interscanner variability with an anthropomorphic body CT phantom
    Bernard A Birnbaum
    Department of Radiology, New York University Medical Center, 560 First Ave, IRM 232, New York, NY 10016, USA
    Radiology 242:109-19. 2007
    ..To determine the dependence of absolute computed tomographic (CT) attenuation values on multi-detector row CT scanner type, convolution kernel, and tube current by using an anthropomorphic phantom...
  46. ncbi Effective x-ray attenuation measurements with full field digital mammography
    John J Heine
    The H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612 4799, USA USA
    Med Phys 33:4350-66. 2006
    ..The work indicates that it is possible to make quantitative attenuation coefficient measurements from a system designed for clinical purposes...
  47. ncbi Step-and-shoot data acquisition and reconstruction for cardiac x-ray computed tomography
    Jiang Hsieh
    GE Healthcare Technologies, Waukesha, Wisconsin 53188, USA
    Med Phys 33:4236-48. 2006
    ..Computer simulations, phantom experiments, and clinical studies were conducted to validate our approach...
  48. ncbi Accurate scaling of digital radiographs of the pelvis. A prospective trial of two methods
    S Wimsey
    Department of Orthopaedic Surgery, Queen Alexandra Hospital, Portsmouth PO6 3LY, UK
    J Bone Joint Surg Br 88:1508-12. 2006
    ..99% (0% to 16.67%). The coin method was significantly more accurate (p < 0.001). It was also reliable and radiographer friendly. We recommend it as the method of choice for scaling radiographs of the pelvis before hip surgery...
  49. ncbi CT virtual intravascular endoscopy in the visualization of fenestrated stent-grafts
    Zhonghua Sun
    Discipline of Medical Imaging, Department of Imaging and Applied Physics, Curtin University of Technology, Perth, Western Australia 6845, Australia
    J Endovasc Ther 15:42-51. 2008
    ..To report the diagnostic value of computed tomographic (CT) virtual intravascular endoscopy (VIE) in the assessment of patients with abdominal aortic aneurysm (AAA) treated with fenestrated endovascular grafts...
  50. ncbi Computer-aided detection of pulmonary embolism: influence on radiologists' detection performance with respect to vessel segments
    Marco Das
    Department of Diagnostic Radiology, RWTH Aachen University, Pauwelsstr 30, 52072 Aachen, Germany
    Eur Radiol 18:1350-5. 2008
    ..0001). CAD performance at the lobar level was 87%, at the segmental 90% and at the subsegmental 77%. With the use of CAD for PE, the detection performance of radiologists can be improved...
  51. ncbi Improved cancer detection using computer-aided detection with diagnostic and screening mammography: prospective study of 104 cancers
    Judy C Dean
    AJR Am J Roentgenol 187:20-8. 2006
    ....
  52. ncbi Dual-source CT cardiac imaging: initial experience
    Thorsten R C Johnson
    Department of Clinical Radiology, University of Munich Grosshadern Campus, Marchioninistrasse 15, 81377, Munich, Germany
    Eur Radiol 16:1409-15. 2006
    ..Dual-source CT offers very robust diagnostic image quality in a wide range of heart rates. The high temporal resolution now also makes a functional evaluation of the heart valves and myocardium possible...
  53. pmc Automated classification of lung bronchovascular anatomy in CT using AdaBoost
    Robert A Ochs
    Department of Biomedical Physics, University of California Los Angeles, CA 90095, USA
    Med Image Anal 11:315-24. 2007
    ..009, 0.945+/-0.018, 0.953+/-0.016, and 0.931+/-0.015, respectively. The strong results suggest that this could be an effective input to higher-level anatomical based segmentation models with the potential to improve CAD performance...
  54. ncbi Removal of arterial wall calcifications in CT angiography by local subtraction
    Marcel van Straten
    Department of Medical Physics, Academic Medical Center, PO box 22660 1100 DD, Amsterdam, The Netherlands
    Med Phys 30:761-70. 2003
    ..We conclude that the local subtraction method is less subjective and more accurate than thresholding. Best results are obtained by use of a small pitch, at the expense of the volume covered during a single breath hold...
  55. ncbi Optimal vascular and parenchymal contrast enhancement: the current state of the art
    Dominik Fleischmann
    Department of Radiology, Stanford University Medical Center, 300 Pasteur Drive, Room S 072, Stanford, CA 94305 5105, USA
    Radiol Clin North Am 47:13-26. 2009
    ..Automated tube current modulation and weight-based injection protocols allow individual optimization of radiation exposure and reduce interindividual variability of CM enhancement...
  56. ncbi Assessing the impact of CAD on the sensitivity and specificity of film readers
    P Taylor
    CHIME, Royal Free and University College Medical School, University College London, London, UK
    Clin Radiol 59:1099-105. 2004
    ..To assess the impact of computer-aided detection (CAD) prompts on film readers' sensitivity and specificity...
  57. ncbi The use of computer-aided detection for the assessment of pulmonary arterial filling defects at computed tomographic angiography
    Anna C Walsham
    Department of Medical Imaging, University Health Network, Toronto, ON, Canada
    J Comput Assist Tomogr 32:913-8. 2008
    ..To validate a computer-aided detection (CAD) tool for the detection of pulmonary arterial filling defects at computed tomographic pulmonary angiography (CTPA) and to assess its benefit for readers of different levels of experience...
  58. ncbi Effects of incorrect computer-aided detection (CAD) output on human decision-making in mammography
    Eugenio Alberdi
    Centre for Software Reliability and the Department of Psychology, City University, Northampton Square, London, UK
    Acad Radiol 11:909-18. 2004
    ..Study 1 was designed to elucidate the effects of computer failure on human performance. Study 2 was conducted to clarify unexpected findings from Study 1...
  59. ncbi Three-dimensional reconstruction allows accurate quantification and length measurements of coronary artery stenoses
    Harald Rittger
    Medizinische Klinik II, Klinikum Coburg, Coburg, Germany
    EuroIntervention 5:127-32. 2009
    ..Israel) as compared to a validated quantitative coronary angiography (QCA) system (Siemens Quantcor, Siemens Medical Solutions)...
  60. ncbi Multislice computed tomography angiography of the abdominal arteries: comparison between computed tomography angiography and digital subtraction angiography findings in 52 cases
    Christoph A Stueckle
    Department of Radiology and Nuclear Medicine, Marienhospital Herne, University Hospital of Ruhr University Bochum, Herne, Germany
    Australas Radiol 48:142-7. 2004
    ..75 for occlusions and 0.77 for calcifications. The specificity was 1.0 in all cases. Multislice CT angiography seems to be similar to conventional digital subtraction angiography for abdominal vessels if multiplanar projections are used...
  61. ncbi Detection and classification performance levels of mammographic masses under different computer-aided detection cueing environments
    Bin Zheng
    Department of Radiology, University of Pittsburgh, Magee Womens Hospital, Pittsburgh, PA, USA
    Acad Radiol 11:398-406. 2004
    ..The authors evaluated the impact of different computer-aided detection (CAD) cueing conditions on radiologists' performance levels in detecting and classifying masses depicted on mammograms...
  62. ncbi Finite element models predict cancellous apparent modulus when tissue modulus is scaled from specimen CT-attenuation
    Benjamin C Bourne
    Sibley School of Mechanical and Aerospace Engineering, Aerospace Engineering, Cornell University, 219 Upson Hall, Ithaca, NY 14853 7501, USA
    J Biomech 37:613-21. 2004
    ....
  63. ncbi An evaluation of the impact of computer-based prompts on screen readers' interpretation of mammograms
    P M Taylor
    Centre for Health Informatics and Multiprofessional Education, University College London, Archway Campus, Highgate Hill, London, UK
    Br J Radiol 77:21-7. 2004
    ..No difference in impact of prompts was found for well or poorly performing film readers. The result suggests that this version of the ImageChecker would not have a significant impact on the UK screening programme...
  64. ncbi Coronary artery calcium quantification at multi-detector row helical CT versus electron-beam CT
    William Stanford
    Department of Radiology, College of Medicine, University of Iowa, 200 Hawkins Dr, Iowa City, IA 52242, USA
    Radiology 230:397-402. 2004
    ..To compare coronary artery calcium scores from a multi-detector row helical computed tomographic (CT) scanner with those from an electron-beam CT scanner, with emphasis on subjects with calcium scores less than 400...
  65. ncbi Computer-aided detection versus independent double reading of masses on mammograms
    Nico Karssemeijer
    Department of Radiology, University Medical Center Nijmegen, Geert Grooteplein 18, 6525 GA Nijmegen, The Netherlands
    Radiology 227:192-200. 2003
    ..To evaluate the use of a computer-aided detection (CAD) system (designed for mammographic mass detection) to help improve mass interpretation and to compare CAD results with independent double-reading results...
  66. ncbi Computer-aided diagnosis in high resolution CT of the lungs
    Ingrid C Sluimer
    Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
    Med Phys 30:3081-90. 2003
    ..Performance of the system is shown to approach that of two expert radiologists in diagnosing the local regions of interest, with an area under the ROC curve of 0.862 for the CAD scheme versus 0.877 and 0.893 for the radiologists...
  67. ncbi Clinical performance of computer-assisted detection (CAD system in detecting carcinoma in breasts of different densities
    W T Ho
    Department of Radiology, Queen Mary Hospital, Pokfulam, Hong Kong
    Clin Radiol 58:133-6. 2003
    ..To determine the clinical performance of a computer-assisted detection (CAD) system in detecting carcinoma in breasts of different densities...
  68. ncbi Quantitative computerized analysis of diffuse lung disease in high-resolution computed tomography
    Yoshikazu Uchiyama
    Kurt Rossmann Laboratories for Radiologic Image Research, Department of Radiology, The University of Chicago, 5841 S Maryland Ave, Chicago, Illinois 60637, USA
    Med Phys 30:2440-54. 2003
    ..The specificity in detecting a normal ROI was 88.1% (940/1067). This computerized method may be useful in assisting radiologists in their assessment of diffuse lung disease in HRCT images...
  69. ncbi Reproducibility of prompts in computer-aided detection (CAD) of breast cancer
    C G Taylor
    South West London Breast Screening Service, London, UK
    Clin Radiol 58:733-8. 2003
    ..We evaluated the reproducibility of prompts using the R2 ImageChecker M2000 computer-aided detection (CAD) system...
  70. ncbi A dynamic approach to identifying desired physiological phases for cardiac imaging using multislice spiral CT
    M Vembar
    Philips Medical Systems, CT Engineering, Advanced Systems Group, 595 Miner Road, Highland Heights, Ohio 44143, USA
    Med Phys 30:1683-93. 2003
    ..Using these estimates in characterizing cardiac motion also provides realistic simulation models for higher heart rates and also in optimizing volume reconstructions for individual segments of the cardiac anatomy...
  71. ncbi Assessment of reproducibility and accuracy in templating hybrid total hip arthroplasty using digital radiographs
    M J Oddy
    Department of Orthopaedics, The Norfolk and Norwich University Hospital NHS Trust, Colney Lane, Norwich, Norfolk NR4 7UZ, UK
    J Bone Joint Surg Br 88:581-5. 2006
    ..9%. On-screen templating of digital radiographs with standard acetate templates is accurate and reproducible if a radiopaque marker such as a ten-pence coin is included when the original radiograph is taken...
  72. ncbi Comparison of analog and digital preoperative planning in total hip and knee arthroplasties. A prospective study of 173 hips and 65 total knees
    Bertram The
    Department of Orthopaedic Surgery, Groningen University Hospital, Hanzeplein 1, NL 9700 RB Groningen, The Netherlands
    Acta Orthop 76:78-84. 2005
    ..Digital correction of the magnification factor is expected to yield more accurate and reliable preoperative plans. We hypothesized that digital templating would be more accurate than manual templating for total hip and knee arthroplasties...
  73. ncbi Potential of image-guidance, gating and real-time tracking to improve accuracy in pulmonary stereotactic body radiotherapy
    Matthias Guckenberger
    Department of Radiation Oncology, Julius Maximilians University, Wuerzburg, Germany
    Radiother Oncol 91:288-95. 2009
    ..To evaluate the potential of image-guidance, gating and real-time tumor tracking to improve accuracy in pulmonary stereotactic body radiotherapy (SBRT)...
  74. ncbi Digital correction of magnification in pelvic x rays for preoperative planning of hip joint replacements: theoretical development and clinical results of a new protocol
    B The
    Department of Orthopedic Surgery, University Medical Center Groningen, Hanzeplein 1, 9700 RB, Groningen, The Netherlands
    Med Phys 32:2580-9. 2005
    ..Future research might clarify if a strict calibration protocol, as presented in this study, results in more accurate preoperative planning of hip joint replacements...
  75. ncbi Semiautomated four-dimensional computed tomography segmentation using deformable models
    Dustin Ragan
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Med Phys 32:2254-61. 2005
    ..This technique has the potential to facilitate contour delineation in 4D CT image data sets; and future evolution of the software is expected to improve the process...
  76. pmc Technical report on semiautomatic segmentation using the Adobe Photoshop
    Jin Seo Park
    Department of Anatomy, Ajou University School of Medicine, 5 Woncheon dong, Yeongtong Gu, Suwon, 443 749, South Korea
    J Digit Imaging 18:333-43. 2005
    ..Proper segmentation was verified by making 3D images from the segmented images. Semiautomatic segmentation using Adobe Photoshop is expected to be widely used for segmentation of anatomical structures in various medical images...
  77. pmc Preliminary investigation of computer-aided detection of pulmonary embolism in three-dimensional computed tomography pulmonary angiography images
    Chuan Zhou
    Department of Radiology, University of Michigan, Ann Arbor, CGC B2103, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA
    Acad Radiol 12:782-92. 2005
    ..We sought to develop a computer-aided diagnosis (CAD) system for assisting radiologists in the detection of pulmonary embolism (PE) on computed tomography pulmonary angiographic (CTPA) images...
  78. ncbi The manufacturer's perspective
    J Roehrig
    R2 Technology, Inc, 1195 W Fremont Ave, Sunnyvale, CA 94087, USA
    Br J Radiol 78:S41-5. 2005
    ....
  79. ncbi A computer-aided detection system for the evaluation of breast cancer by mammographic appearance and lesion size
    Rachel F Brem
    Department of Radiology, The George Washington University, 2150 Pennsylvania Ave NW, Washington, DC 21117, USA
    AJR Am J Roentgenol 184:893-6. 2005
    ..CAD was highly effective in detecting even the smallest lesions, with a sensitivity of 92% for lesions of 5 mm or less. CAD is a useful tool for the detection of breast cancer...
  80. ncbi Computer-aided detection in direct digital full-field mammography: initial results
    F Baum
    Department of Radiology, Georg August Universitat Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Eur Radiol 12:3015-7. 2002
    ..Results are equivalent to the results reported for CAD analysis of secondarily digitized image data. Sensitivity for microcalcifications is acceptable and for masses is low. The number of false-positive marks per image should be reduced...
  81. ncbi Uniform image quality achieved by tube current modulation using SD of attenuation in coronary CT angiography
    Gham Hur
    Department of Radiology, Inje University Ilsanpaik Hospital, Daewha dong, Ilsan seogu, Goyang si, Gyuanggi do 411 706, South Korea
    AJR Am J Roentgenol 189:188-96. 2007
    ....
  82. ncbi Computer aided detection of masses in mammograms as decision support
    N Karssemeijer
    Radboud University Nijmegen Medical Centre, Department of Radiology, Nijmegen, The Netherlands
    Br J Radiol 79:S123-6. 2006
    ..No significant difference was found between the results of these two methods. Both methods improved single reading results significantly...
  83. ncbi MDCT for the diagnosis of acute pulmonary embolism
    Cornelia Schaefer-Prokop
    Department of Radiology, Academic Medical Center AMC, University of Amsterdam, The Netherlands
    Eur Radiol 15:D37-41. 2005
    ..Diagnostic algorithms are outlined that describe the role of CT in context with the pretest probability, the D-Dimer, lower limb sonography and scintigraphy...
  84. ncbi Computer-based detection and prompting of mammographic abnormalities
    S M Astley
    Imaging Science and Biomedical Engineering, Stopford Building, Oxford Road, Manchester M13 9PT, UK
    Br J Radiol 77:S194-200. 2004
    ..This paper reviews progress in abnormality detection, the strengths and the weaknesses of CAD, and the methodologies used to evaluate CAD in a clinical setting...
  85. ncbi Blood flow patterns in an anatomically realistic coronary vessel: influence of three different reconstruction methods
    B Berthier
    Universite de Technologie de Compiegne, UMR CNRS 6600 Biomécanique et Génie Biomédical, Compiegne, France
    J Biomech 35:1347-56. 2002
    ....
  86. ncbi Implications of unchanged detection criteria with CAD as second reader of mammograms
    Hans Bornefalk
    Department of Physics, KTH, Stockholm, Sweden
    Med Phys 33:922-9. 2006
    ..5% relative decrease in sensitivity compared to that without using a stricter initial criterion by the radiologist. For microcalcifications the corresponding values are 7% and 0.2%...
  87. ncbi Three-dimensional coronary imaging for the ostium of the left anterior descending artery
    Kenji Sadamatsu
    Department of Cardiology, St Mary s Hospital, Kurume, Japan
    Int J Cardiovasc Imaging 25:223-8. 2009
    ..The optimal views selected using the 3D system provided clearer images of the ostium of the left anterior descending artery with less overlapping and foreshortening...
  88. ncbi Computer-aided detection in clinical environment: benefits and challenges for radiologists
    Elizabeth A Krupinski
    Radiology 231:7-9. 2004
  89. ncbi Automated finite-element analysis for deformable registration of prostate images
    Jessica R Crouch
    Computer Science Department, Old Dominion University, Norfolk, VA 23529, USA
    IEEE Trans Med Imaging 26:1379-90. 2007
    ..Encouraging results are presented for the registration of CT image pairs which exhibit deformation caused by pressure from an endorectal imaging probe and deformation due to swelling...
  90. ncbi Path planning for virtual bronchoscopy
    Mohamadreza Negahdar
    Dept of Biomedical Systems and Medical Physics, Tehran University of Medica Sciences, Iran
    Conf Proc IEEE Eng Med Biol Soc 1:156-9. 2006
    ..The computation time of our algorithm is faster than similar works and there were no missing or false branches in the final path of airways. The planned path is suitable for quantitative airway analysis and smooth virtual navigation...
  91. ncbi A robust technique for 2D-3D registration
    Ren Hui Gong
    School of Computering, Queen s University, Kingston, Ontario K7L 3N6, Canada
    Conf Proc IEEE Eng Med Biol Soc 1:1433-6. 2006
    ..We show that, under the same testing conditions, our proposed technique outperforms the conventional simplex-based method in capture range and robustness while providing comparable accuracy and computation time...
  92. ncbi Registration-derived estimates of local lung expansion as surrogates for regional ventilation
    Joseph M Reinhardt
    Department of Biomedical Engineering, The University of Iowa, Iowa City, IA 52242, USA
    Inf Process Med Imaging 20:763-74. 2007
    ..We compare lung expansion estimated across five pressure changes to a xenon CT based measure of specific ventilation, and have shown good agreement (linear regression, r2 = 0.89 during gas wash-in) in one animal...
  93. ncbi Novel image registration quality evaluator (RQE) with an implementation for automated patient positioning in cranial radiation therapy
    Jian Wu
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611, USA
    Med Phys 34:2099-112. 2007
    ..987). Clinical implementation of a RQE could potentially reduce the involvement of the human observer for routine patient positioning verification, while increasing setup accuracy and reducing setup verification time...
  94. ncbi Automated segmentation of the liver from 3D CT images using probabilistic atlas and multi-level statistical shape model
    Toshiyuki Okada
    Division of Image Analysis, Osaka University Graduate School of Medicine, Suita, Osaka 565 0871, Japan
    Med Image Comput Comput Assist Interv 10:86-93. 2007
    ..In experiments, we demonstrate that segmentation accuracy improved by using the initial region obtained with PA and the introduced constraint for ML-SSM...
  95. ncbi Lung nodule detection via Bayesian voxel labeling
    Paulo R S Mendonça
    GE Global Research, One Research Circle, Niskayuna, NY 12309, USA
    Inf Process Med Imaging 20:134-46. 2007
    ..We provide, under explicit modeling assumptions, closed-form expressions for all the probability distributions involved. The technique is applied to real data, and we present a discussion of its performance...
  96. ncbi Segmentation of neck lymph nodes in CT datasets with stable 3D mass-spring models segmentation of neck lymph nodes
    Jana Dornheim
    Otto von Guericke Universitat Magdeburg, Universitatsplatz 2, 39106 Magdeburg, Germany
    Acad Radiol 14:1389-99. 2007
    ..We present a stable 3D mass-spring model for lymph node segmentation in computed tomography (CT) datasets...
  97. ncbi New CTA protocol and 2D-3D registration method for liver catheterization
    Martin Groher
    Technische Universitat Munchen, Germany
    Med Image Comput Comput Assist Interv 9:873-81. 2006
    ..This algorithm shows good convergence and proves to be robust against deformation changes, which is demonstrated through studies on one phantom and three patients...
  98. ncbi Automatic registration between reference and on-board digital tomosynthesis images for positioning verification
    Lei Ren
    Department of Radiation Oncology, Physics, Duke University Medical Center, DUMC Box 3295, Durham, North Carolina 27710, USA
    Med Phys 35:664-72. 2008
    ..Results also showed that the hybrid registration technique had much larger capture ranges than the static method alone in registering the out-of-plane rotations...
  99. ncbi A probabilistic framework based on hidden markov model for fiducial identification in image-guided radiation treatments
    Zhiping Mu
    Accuray Incorporated, 1310 Chesapeake Terrace, Sunnyvale, CA 94089, USA
    IEEE Trans Med Imaging 27:1288-300. 2008
    ..In the experiments, the algorithm demonstrated a large tracking range, computational efficiency, ease of use, and robustness that meet the requirements for clinical use...
  100. ncbi Accurate registration of random radiographic projections based on three spherical references for the purpose of few-view 3D reconstruction
    Ralf Schulze
    Department of Oral Surgery and Oral Radiology, Johannes Gutenberg University, Dental School, Mainz 55131, Germany
    Med Phys 35:546-55. 2008
    ..The method facilitates extraction of 3D information from only few projections obtained from off-the-shelf radiographic projection units without the need for costly hardware. Technical requirements as well as radiation dose are low...
  101. pmc An ellipse-fitting based method for efficient registration of breast masses on two mammographic views
    Jiantao Pu
    Department of Radiology, University of Pittsburgh, 3362 Fifth Avenue, Pittsburgh, Pennsylvania 15213, USA
    Med Phys 35:487-94. 2008
    ..The results demonstrate the feasibility of the proposed method to automatically identify masses depicted on CC and MLO views, which may improve future development of multiview based CAD schemes...

Research Grants68

  1. Computerized Analysis of Mesothelioma on CT Scans
    Samuel Armato; Fiscal Year: 2009
    ....
  2. 3D Massive Training ANN for CAD for Colon Cancer in CT Colonography
    Kenji Suzuki; Fiscal Year: 2010
    ....
  3. COMPUTER AIDED DIAGNOSIS IN CT OF THE THORAX
    Samuel Armato; Fiscal Year: 2004
    ....
  4. Standard Database for CT Lung Images
    Samuel Armato; Fiscal Year: 2006
    ..The ideas resented in this proposal are expected to stimulate the efforts of the Consortium toward that goal. ..
  5. Monochromatic Phase-Contrast Breast Cancer Radiography
    Edwin Donnelly; Fiscal Year: 2005
    ..Image quality of all images will be judged by an experienced mammographer. ..
  6. Phase Contrast Computed Tomography Scanner
    Edwin Donnelly; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  7. ROC Analysis of Imaging System Evaluations
    David Gur; Fiscal Year: 2002
    ..abstract_text> ..
  8. Interactive CAD for Mammography
    Bin Zheng; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  9. Assessment of Variance Structure in ROC Studies
    David Gur; Fiscal Year: 2006
    ..e., those that are the less demanding of the expensive resources of gathering patient cases and expanding radiologists reading time. ..
  10. DETECTION AND LOCALIZATION IN MAMMOGRAPHY
    Bin Zheng; Fiscal Year: 2002
    ..It will also investigate augmented CAD cues that code information about correlations between the two ipsilateral projections. ..
  11. Exploration of Stereo Display for Lung Cancer Screening
    Xiao Hui Wang; Fiscal Year: 2005
    ..We expect to demonstrate that the use of a stereo display for lung cancer screening will result in improved accuracy and efficiency, and this could greatly increase the efficacy of this screening process. ..
  12. The Laboratory Effect in Breast Cancer Detection Studies
    David Gur; Fiscal Year: 2007
    ..The comparison we are attempting to do is at the very core of our ability (or not) to generalize laboratory observer performance data to the general clinical environment in a valid manner. ..
  13. PREVALENCE EFFECT IN IMAGING SYSTEMS EVALUATIONS
    David Gur; Fiscal Year: 2001
    ..abstract_text> ..
  14. OBSERVER PERFORMANCE STUDIES-READER SELECTION & TRAINING
    David Gur; Fiscal Year: 2002
    ..While they proposed to continue to investigate several aspects in this regard, the current proposal would focus on the possible effects of observer (reader) selection and training on study design and results. ..
  15. Comparing Performance Under FROC Paradigm - A Non Parametirc Approach
    David Gur; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  16. Data Consistency Based Motion Artifact Reduction for Head CT
    Hengyong Yu; Fiscal Year: 2008
    ..Hence, the proposed techniques promise to be translated for clinical use and should generate great healthcare benefits, especially for children. [unreadable] [unreadable] [unreadable]..
  17. ROC Analysis of Imaging System Evaluations
    David Gur; Fiscal Year: 2009
    ..We will develop closed-form solutions for the ANOVA procedure conducted on all possible bootstrap values. ..
  18. MIPS XII Conference
    Elizabeth Krupinski; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  19. Optimized Compression for Telepathology Virtual Slides
    Elizabeth Krupinski; Fiscal Year: 2009
    ....
  20. Hybrid Nuclear/X-ray Projection System for Mouse Imaging
    John Boone; Fiscal Year: 2005
    ..abstract_text> ..
  21. Quantification of coronary calcium mass by dual energy fluoroscopy
    Sabee Molloi; Fiscal Year: 2009
    ..Dual-energy imaging, because of its motion insensitivity, can serve as a foundation for quantitative cardiac analysis to proceed. ..
  22. Fractional flow reserve measurement based on coronary angiographic images
    SABEE Y MOLLOI; Fiscal Year: 2010
    ..This quantification technique could be used to measure fractional flow reserve in patients undergoing standard coronary arteriography. ..
  23. Medical Image Perception Society Confrence XI
    Elizabeth Krupinski; Fiscal Year: 2005
    ..abstract_text> ..
  24. X-ray imaging using edge-on-microchannel plate detectors
    Sabee Molloi; Fiscal Year: 2006
    ..It can potentially provide a high-resolution detector with significant reduction in patient dose for digital mammography. ..
  25. Digital Mammography: Advanced Computer-Aided Breast Can*
    Heang Ping Chan; Fiscal Year: 2007
    ..abstract_text> ..
  26. Tumor perfusion in small animals with tomographic digital subtraction angiography
    Cristian Badea; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  27. Non Iterative Methods for 3D SPECT Image Reconstruction
    Xiaochuan Pan; Fiscal Year: 2005
    ....
  28. Computer Aided Diagnosis of Lung Cancer
    Heang Ping Chan; Fiscal Year: 2006
    ..When fully developed and clinically implemented, a CAD system for lung nodules will increase the efficacy of lung cancer screening with helical CT, improve early detection, and improve the chance of survival of patients. ..
  29. OPTIMIZING SOFTCOPY DISPLAYS FOR DIGITAL MAMMOGRAPHY
    Elizabeth Krupinski; Fiscal Year: 2002
    ..The JND metrix model will then be used to systematically explore and optimize CRT design tradeoffs for current and future digital-mammography display systems. ..
  30. Conference--Medical Image Perception
    Elizabeth Krupinski; Fiscal Year: 2003
    ..This grant will be used to provide financial support for about 12 graduate students and residents, as well as logistic support for publicity and program printing. ..
  31. Quantification of Regional coronary Blood Flow
    Sabee Molloi; Fiscal Year: 2003
    ..This quantification technique could be used to measure regional myocardial perfusion in patients undergoing standard coronary arteriography. ..
  32. OPTIMIZING SOFTCOPY DISPLAYS FOR DIGITAL MAMMOGRAPHY
    Elizabeth Krupinski; Fiscal Year: 2003
    ..The JND metrix model will then be used to systematically explore and optimize CRT design tradeoffs for current and future digital-mammography display systems. ..
  33. Feasibility of CT in high risk breast cancer patients
    John Boone; Fiscal Year: 2003
    ..The results of this investigation should provide a clear understanding of the potential of breast CT as a tool to reduce breast cancer mortality in the population of women with dire risk of breast cancer. ..
  34. PATIENT SPECIFIC MODELS IN LUNG CANCER SCREENING WITH CT
    Matthew Brown; Fiscal Year: 2004
    ..4] To compare radiologist accuracy and interpretation times of HR-hCT scans, both with and without assistance from the automated detection system, against pre-existing nodule detection methods. ..
  35. Non Iterative Methods for 3D SPECT Image Reconstruction
    Xiaochuan Pan; Fiscal Year: 2002
    ....
  36. FOURIER AND SPLINE BASED RECONSTRUCTIONS IN HELICAL CT
    Xiaochuan Pan; Fiscal Year: 2001
    ....
  37. Breast CT scanner for earlier cancer detection
    John Boone; Fiscal Year: 2002
    ..that particularly warrant screening using breast CT. The Phase II trial will shed more light on this issue. ..
  38. PERCEPTUAL MODEL FOR WORKSTATION DISPLAY OPTIMIZATION
    Dev Chakraborty; Fiscal Year: 2002
    ..Also to be generated are iso-contour plots of the effects of common workstation variables on image quality in both tasks. This will allow digital mammography workstations to be more intelligently used. ..
  39. Multimodality CAD system with image references for breast mass characterization
    Berkman Sahiner; Fiscal Year: 2007
    ..Any reduction in this number without a decrease in breast cancer detection sensitivity will decrease health care costs, as well as contribute to the well-being of the patient by reducing anxiety and morbidity. ..
  40. Iterative Reconstruction for Breast Tomosynthesis
    STEPHEN GLICK; Fiscal Year: 2009
    ..Evaluation and optimization of different imaging system designs and acquisition processes will be conducted by evaluating lesion detection accuracy using realistically simulated tomosynthesis breast images. ..
  41. Feasibility of CT Mammography Using Flat Panel Detectors
    STEPHEN GLICK; Fiscal Year: 2002
    ..These models will be determined based on the statistical characterization of surgically removed lesion and breast tissue specimens. ..
  42. Regional Lung Mechanics by 3D Image Registration
    Joseph M Reinhardt; Fiscal Year: 2010
    ..This information is now critical to the development and evaluation of new pulmonary disease therapies. ..
  43. Early Detection of Lung Cancer via Bi Plane Correlation
    Ehsan Samei; Fiscal Year: 2002
    ..The findings will be used to demonstrate the capability of the approach for improving the detection of lung nodules, and thus the prognosis of lung cancer. ..
  44. Phase II validation of 4-dimensional computed tomography derived ventilation for
    Thomas Guerrero; Fiscal Year: 2008
    ..Our new imaging method uses equipment already available in almost every radiation oncology clinic. This study seeks to validate our new ventilation imaging with the present standard method. [unreadable] [unreadable] [unreadable]..
  45. Non-Invasive Localization of Vulnerable Plaques
    Cynthia McCollough; Fiscal Year: 2009
    ....
  46. VOLUMETRIC ANALYSIS OF THE AORTA AND ITS BRANCHES
    Geoffrey Rubin; Fiscal Year: 2002
    ....
  47. Better correlation of outcomes with MC dose calculation
    Indrin Chetty; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  48. CCD detector
    Carol Muehleman; Fiscal Year: 2005
    ..Additionally, the optimized facility will greatly enhance the productivity of each user group as a consequence of detector efficiency. ..
  49. Computer Detection of Nodules of the Lung
    Anthony Reeves; Fiscal Year: 2007
    ..The complete detection system will be evaluated with a CT image database that has a ground truth established by multiple radiologist reads. [unreadable] [unreadable]..
  50. Standardizing CT Assessment of Pulmonary Parenchyma
    Juerg Tschirren; Fiscal Year: 2006
    ..Developing AMFM into a screening tool to complement lung cancer screening for at-risk patients is another option we are exploring for the long-term. [unreadable] [unreadable]..
  51. Breast Cancer Imaging Using a Solid-State SPECT Camera
    G Zeng; Fiscal Year: 2005
    ..abstract_text> ..
  52. Feasibility of CT Mammography Using Flat Panel Detectors
    STEPHEN GLICK; Fiscal Year: 2005
    ..These models will be determined based on the statistical characterization of surgically removed lesion and breast tissue specimens. ..
  53. NOVEL X-RAY TECHNOLOGY FOR DEGENERATIVE JOINT DISEASE
    Carol Muehleman; Fiscal Year: 2006
    ..Our long-term goal is to identify and localize initial phases of cartilage degeneration and follow their progression with the ultimate aim of monitoring disease progression and therapeutic interventions. ..
  54. Resolution requirements for mammographic displays
    Ehsan Samei; Fiscal Year: 2004
    ..The results will be used to formulate recommendations to the breast imaging community concerning display resolution criteria for safe and optimized soft-copy display of digital mammograms. ..
  55. Radio-Immunotherapy (RIT) Planning Using SPECT
    LAWRENCE ZENG; Fiscal Year: 2004
    ..Novel image reconstruction algorithms will be developed to provided quantitative SPECT images. Our hypothesis will be verified through human observer studies and Channelized Hotelling observer studies. ..
  56. Image Reconstruction with Solid Srate SPECR
    LAWRENCE ZENG; Fiscal Year: 2005
    ..abstract_text> ..
  57. IMPROVED QUANTITATIVE ACCURACY OF SPECT-PET IMAGING
    STEPHEN GLICK; Fiscal Year: 2001
    ....
  58. Pulmonary Lobar Analysis by 3D Surface Detection
    Juerg Tschirren; Fiscal Year: 2007
    ..The proposed methods are urgently needed to take advantage of emerging therapies for the early treatment of lung disease. [unreadable] [unreadable] [unreadable]..
  59. Computer-Aided Detection of Pulmonary Embolism on CT Pulmonary Angiography
    Chuan Zhou; Fiscal Year: 2007
    ..CAD will potentially reduce missed PEs and improve the chance of timely treatment of patients, thus reducing the mortality rate and speed up recovery from this condition. [unreadable] [unreadable]..
  60. PERCEPTUAL MODEL FOR WORKSTATION DISPLAY OPTIMIZATION
    Dev Chakraborty; Fiscal Year: 2003
    ..Also to be generated are iso-contour plots of the effects of common workstation variables on image quality in both tasks. This will allow digital mammography workstations to be more intelligently used. ..
  61. Improving Radiologist Detection of Lung Nodules with CAD
    Geoffrey Rubin; Fiscal Year: 2008
    ..abstract_text> ..
  62. Bi-Plane Correlation Imaging: Detection of Lung Cancer
    Ehsan Samei; Fiscal Year: 2007
    ..The findings will be used to substantiate the capability of BCI for improving the early detection of lung nodules and to optimize its performance on actual clinical cases. ..
  63. Efficient Interpretation of 3D Vascular Image Data
    Sandy Napel; Fiscal Year: 2005
    ..Our overall goal is to change and validate the way crosssectional images are interpreted in general, thus resulting in improved accuracy and efficiency in the assessment of increasingly large volumes of medical image data. ..
  64. Mouse Modeling Techniques for Bioluminescence Tomography
    Wenxiang Cong; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  65. 3D Time-resolved Tomographic Interventional Platform
    Guang Hong Chen; Fiscal Year: 2004
    ....
  66. TOMOSYNTHESIS FOR IMPROVED PULMONARY NODULE DETECTION
    James Dobbins; Fiscal Year: 2005
    ..These pilot studies will characterize and minimize effects of patient motion, optimize the number of reconstructed planes and patient entrance exposure, and evaluate slice viewing vs volume rendering. ..
  67. Integrated Tomosynthetic Perfusion and Cone-beam CT Imaging on a C-arm Gantry
    Guang Hong Chen; Fiscal Year: 2009
    ..The new interventional platform will not only benefit those at researchcenters,but also will enable image-guided interventional stroke treatmentsfor hospitals without advanced imaging facilities. ..