patient controlled analgesia

Summary

Summary: Relief of PAIN, without loss of CONSCIOUSNESS, through ANALGESIC AGENTS administered by the patients. It has been used successfully to control POSTOPERATIVE PAIN, during OBSTETRIC LABOR, after BURNS, and in TERMINAL CARE. The choice of agent, dose, and lockout interval greatly influence effectiveness. The potential for overdose can be minimized by combining small bolus doses with a mandatory interval between successive doses (lockout interval).

Top Publications

  1. ncbi Comparison of 2 concentrations of levobupivacaine in postoperative patient-controlled epidural analgesia
    Mira Dernedde
    Department of Anesthesiology, University Hospital Center, 6000 Charleroi, Belgium
    J Clin Anesth 17:531-6. 2005
  2. ncbi Comparison of analgesic methods for total knee arthroplasty: metabolic effect of exogenous glucose
    Giovanni Mistraletti
    Department of Anesthesia, McGill University Health Centre, Montreal, Quebec, Canada
    Reg Anesth Pain Med 31:260-9. 2006
  3. ncbi Comparison of two patient-controlled analgesia techniques on neuropsychological functioning in the immediate postoperative period
    Benzion Beilin
    Department of Anesthesiology, Rabin Medical Center, Hasharon Hospital, Petah Tiqva, Israel
    J Clin Exp Neuropsychol 30:674-82. 2008
  4. ncbi Effectiveness of acute postoperative pain management: I. Evidence from published data
    S J Dolin
    Pain Clinic, St Richard s Hospital, Chichester PO19 4E, UK
    Br J Anaesth 89:409-23. 2002
  5. ncbi Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy
    Wen Ying Chou
    Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital, Taipei, Taiwan
    Anesthesiology 105:334-7. 2006
  6. ncbi Ease of care with patient controlled analgesia systems: questionnaire development and validation
    Gale Harding
    United BioSource Corporation, Bethesda, Maryland, USA
    J Adv Nurs 59:530-41. 2007
  7. ncbi Does multimodal analgesia with acetaminophen, nonsteroidal antiinflammatory drugs, or selective cyclooxygenase-2 inhibitors and patient-controlled analgesia morphine offer advantages over morphine alone? Meta-analyses of randomized trials
    Nadia Elia
    Division of Anesthesiology, Geneva University Hospitals, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Anesthesiology 103:1296-304. 2005
  8. ncbi Association of mu-opioid receptor gene polymorphism (A118G) with variations in morphine consumption for analgesia after total knee arthroplasty
    W Y Chou
    Department of Anaesthesiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan
    Acta Anaesthesiol Scand 50:787-92. 2006
  9. ncbi Intraarticular patient-controlled regional anesthesia after arthroscopically assisted anterior cruciate ligament reconstruction: ropivacaine/morphine/ketorolac versus ropivacaine/morphine
    Neli Vintar
    Department of Anesthesiology and Intensive Care, University Medical Center, Zaloska 7, 1000 Ljubljana, Slovenia
    Anesth Analg 101:573-8, table of contents. 2005
  10. pmc Is intravenous patient controlled analgesia enough for pain control in patients who underwent thoracoscopy?
    Jie Ae Kim
    Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Korean Med Sci 24:930-5. 2009

Detail Information

Publications245 found, 100 shown here

  1. ncbi Comparison of 2 concentrations of levobupivacaine in postoperative patient-controlled epidural analgesia
    Mira Dernedde
    Department of Anesthesiology, University Hospital Center, 6000 Charleroi, Belgium
    J Clin Anesth 17:531-6. 2005
    ..To evaluate the quality of analgesia and the incidence of side effects of 2 different concentrations of levobupivacaine given as an equal milligram-bolus dose (5 mg) via patient-controlled epidural analgesia after abdominal surgery...
  2. ncbi Comparison of analgesic methods for total knee arthroplasty: metabolic effect of exogenous glucose
    Giovanni Mistraletti
    Department of Anesthesia, McGill University Health Centre, Montreal, Quebec, Canada
    Reg Anesth Pain Med 31:260-9. 2006
    ....
  3. ncbi Comparison of two patient-controlled analgesia techniques on neuropsychological functioning in the immediate postoperative period
    Benzion Beilin
    Department of Anesthesiology, Rabin Medical Center, Hasharon Hospital, Petah Tiqva, Israel
    J Clin Exp Neuropsychol 30:674-82. 2008
    ..PCA-IV patients exhibited significant deterioration in the postoperative period in all the neuropsychological measures, while the PCEA patients exhibited significant deterioration only in one cognitive index, compared to controls...
  4. ncbi Effectiveness of acute postoperative pain management: I. Evidence from published data
    S J Dolin
    Pain Clinic, St Richard s Hospital, Chichester PO19 4E, UK
    Br J Anaesth 89:409-23. 2002
    ..m.) analgesia, patient controlled analgesia (PCA), and epidural analgesia.
  5. ncbi Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy
    Wen Ying Chou
    Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital, Taipei, Taiwan
    Anesthesiology 105:334-7. 2006
    ..The purpose of the current study was to investigate whether this polymorphism contributes to the variability of morphine efficacy in women who undergo abdominal total hysterectomy...
  6. ncbi Ease of care with patient controlled analgesia systems: questionnaire development and validation
    Gale Harding
    United BioSource Corporation, Bethesda, Maryland, USA
    J Adv Nurs 59:530-41. 2007
    This paper is a report of the development and validation of two questionnaires assessing ease of caring for patients receiving patient controlled analgesia from the perspectives of nurses and physical therapists.
  7. ncbi Does multimodal analgesia with acetaminophen, nonsteroidal antiinflammatory drugs, or selective cyclooxygenase-2 inhibitors and patient-controlled analgesia morphine offer advantages over morphine alone? Meta-analyses of randomized trials
    Nadia Elia
    Division of Anesthesiology, Geneva University Hospitals, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Anesthesiology 103:1296-304. 2005
    ..There is evidence that the combination of nonsteroidal antiinflammatory drugs with patient-controlled analgesia morphine offers some advantages over morphine alone...
  8. ncbi Association of mu-opioid receptor gene polymorphism (A118G) with variations in morphine consumption for analgesia after total knee arthroplasty
    W Y Chou
    Department of Anaesthesiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan
    Acta Anaesthesiol Scand 50:787-92. 2006
    ..This study was performed to correlate the A118G polymorphism at OPRM1 with morphine consumption in patients undergoing total knee arthroplasty...
  9. ncbi Intraarticular patient-controlled regional anesthesia after arthroscopically assisted anterior cruciate ligament reconstruction: ropivacaine/morphine/ketorolac versus ropivacaine/morphine
    Neli Vintar
    Department of Anesthesiology and Intensive Care, University Medical Center, Zaloska 7, 1000 Ljubljana, Slovenia
    Anesth Analg 101:573-8, table of contents. 2005
    ..The combination of intraarticular ropivacaine, morphine, and ketorolac was superior to control or to a combination of ropivacaine and morphine...
  10. pmc Is intravenous patient controlled analgesia enough for pain control in patients who underwent thoracoscopy?
    Jie Ae Kim
    Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Korean Med Sci 24:930-5. 2009
    ..This indicates that IV PCA and Epidural PCA are equally effective to control the postoperative pain after VATS lobectomy, which suggests that IV PCA may be used instead of Epidural PCA...
  11. ncbi Patient controlled analgesia for labour: a comparison of remifentanil with pethidine
    J M Blair
    St Helier Hospital, Epsom and St Helier University Hospitals NHS Trust, Wrythe Lane, Carshalton, Surrey SM5 1AA, UK
    Anaesthesia 60:22-7. 2005
    We compared the analgesic efficacy and safety of remifentanil and pethidine via patient controlled analgesia for women in established uncomplicated labour...
  12. ncbi Single-injection thoracic paravertebral block for postoperative pain treatment after thoracoscopic surgery
    A Vogt
    Department of Anaesthesiology, Division of Thoracic Surgery, University Hospital of Bern, Inselspital, 3010 Bern, Switzerland
    Br J Anaesth 95:816-21. 2005
    ..We tested the hypothesis that a single-injection thoracic paravertebral block, performed preoperatively, reduces pain scores after thoracoscopic surgery...
  13. ncbi Effects of nonsteroidal antiinflammatory drugs on patient-controlled analgesia morphine side effects: meta-analysis of randomized controlled trials
    Emmanuel Marret
    Department of Anesthesiology and Critical Care, Tenon University Hospital, 4 rue de la Chine, 75970 Paris Cedex 20, France
    Anesthesiology 102:1249-60. 2005
    ..Pruritus, urinary retention, and respiratory depression were not significantly decreased by NSAIDs...
  14. ncbi Patient-controlled drug delivery for acute postoperative pain management: a review of current and emerging technologies
    Eugene R Viscusi
    Department of Anesthesiology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Reg Anesth Pain Med 33:146-58. 2008
    ..This review will discuss the benefits and drawbacks of both existing and emerging PCA modalities in the context of the ideal PCA system, and provide a critical evaluation of their use in postoperative settings...
  15. ncbi Efficacy of single-dose, multilevel paravertebral nerve blockade for analgesia after thoracoscopic procedures
    Steven E Hill
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesthesiology 104:1047-53. 2006
    ..The purpose of this trial was to compare the efficacy of analgesia from preoperative bupivacaine paravertebral nerve blockade with that from placebo injections...
  16. pmc The effects of ketorolac injected via patient controlled analgesia postoperatively on spinal fusion
    Si Young Park
    Department of Orthopaedic Surgery, Yonsei University College of Medicine, 134 Shinchon dong, Seodaemun gu, Seoul 120 752, Korea
    Yonsei Med J 46:245-51. 2005
    ..The first group (n=30) was infused with ketorolac and fentanyl intravenously via patient controlled analgesia (PCA) postoperatively and the second group (n=58) was infused only with fentanyl...
  17. ncbi Randomized clinical trial comparing epidural anaesthesia and patient-controlled analgesia after laparoscopic segmental colectomy
    A J Senagore
    Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Br J Surg 90:1195-9. 2003
    ..This randomized clinical trial compared the use of thoracic epidural anaesthesia-analgesia (TEA) with morphine patient-controlled analgesia (PCA) for pain relief after laparoscopic colectomy...
  18. ncbi Patient controlled analgesia: redefining its role in an Indian cancer hospital
    Sumitra G Bakshi
    Department of Anesthesia, Tata Memorial Hospital for Cancer, Mumbai, India
    J Pain Palliat Care Pharmacother 24:213-8. 2010
    ..Their protocols shall be suitably amended to ensure that PCA shall be used in immediate postoperative period as a principal modality of pain relief, especially in the above-mentioned group in absence of epidural analgesia...
  19. ncbi Propacetamol versus ketorolac for treatment of acute postoperative pain after total hip or knee replacement
    T J Zhou
    Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center at Dallas, Texas 75390-9068, USA
    Anesth Analg 92:1569-75. 2001
    ..In conclusion, propacetamol (2 g IV) possesses a similar analgesic efficacy to ketorolac (15 or 30 mg IV) after total hip or knee replacement surgery...
  20. ncbi The effects of three different analgesia techniques on long-term postthoracotomy pain
    Mert Senturk
    Department of Anesthesiology, Medical Faculty of Istanbul, University of Istanbul, Turkey
    Anesth Analg 94:11-5, table of contents. 2002
    ..0233; Group Pre-TEA versus Group IV-PCA, P = 0.014). Patients having pain on the second postoperative day had 83% chronic pain. TEA with preoperative initiation is a preferable method in preventing acute and long-term thoracotomy pain...
  21. ncbi Postoperative analgesic effects of celecoxib or rofecoxib after spinal fusion surgery
    S S Reuben
    Department of Anesthesiology, Baystate Medical Center, Springfield, Massachusetts 01199, USA
    Anesth Analg 91:1221-5. 2000
    ..We thus recommend that rofecoxib be used as a preoperative component of pain management that includes PCA morphine in patients undergoing spine stabilization surgery...
  22. ncbi Postoperative patient-controlled analgesia with intravenous tramadol, intravenous fentanyl, epidural tramadol and epidural ropivacaine+fentanyl combination
    S Aygun
    Department of Anaesthesiology and Reanimation, Faculty of Medicine, University of Gaziantep, Gaziantep, Turkey
    Eur J Gynaecol Oncol 25:498-501. 2004
    ..The aim of this study was to compare the effects of IV tramadol, IV fentanyl, epidural tramadol, and an epidural ropivacaine+fentanyl combination in patient-controlled analgesia (PCA) after lower abdominal surgery...
  23. ncbi Effects of perioperative administration of a selective cyclooxygenase 2 inhibitor on pain management and recovery of function after knee replacement: a randomized controlled trial
    Asokumar Buvanendran
    Department of Anesthesiology, Rush Medical College at Rush Presbyterian St Luke s Medical Center, Chicago, Ill 60612, USA
    JAMA 290:2411-8. 2003
    ..Controlling postoperative pain after knee replacement while reducing opioid-induced adverse effects and improving outcomes remains an important challenge...
  24. ncbi A prospective randomized trial on the role of perioperative celecoxib administration for total knee arthroplasty: improving clinical outcomes
    Scott S Reuben
    Department of Anesthesiology, Baystate Medical Center and the Tufts University School of Medicine, Springfield, MA 01199, USA
    Anesth Analg 106:1258-64, table of contents. 2008
    ..The hypothesis of this study is that perioperative administration of celecoxib will improve analgesic efficacy, with a resultant improvement in short- and long-term clinical outcomes after TKA...
  25. ncbi System-related events and analgesic gaps during postoperative pain management with the fentanyl iontophoretic transdermal system and morphine intravenous patient-controlled analgesia
    Sunil J Panchal
    Coalition for Pain Education Foundation, Tampa, Florida, USA
    Anesth Analg 105:1437-41, table of contents. 2007
    ....
  26. ncbi Does a thoracic epidural confer any additional benefit following video-assisted thoracoscopic pleurectomy for primary spontaneous pneumothorax?
    Marta I Fernandez
    Department of Thoracic Surgery, Glenfield Hospital, Leicester, UK
    Eur J Cardiothorac Surg 27:671-4. 2005
    ..Although thoracic epidural analgesia is the gold standard after open thoracic surgical procedures, its use in the management of minimally invasive procedures in this young population has not been extensively studied...
  27. ncbi Ethnic differences in pain perception and patient-controlled analgesia usage for postoperative pain
    Ene Choo Tan
    KK Research Centre, KK Women s and Children s Hospital, and the Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    J Pain 9:849-55. 2008
    ..The ethnic differences in pain score and morphine self-administration persisted after controlling for age, body mass index, and duration of operation...
  28. ncbi The safety and tolerability of the fentanyl HCl iontophoretic transdermal system: an alternative to currently available analgesic modalities
    Leopold Eberhart
    Department of Anaesthesiology and Intensive Care, Philipps University, Marburg, Germany
    J Opioid Manag 3:249-56. 2007
    ..Its efficacy, safety, and tolerability were assessed in several clinical trials, and this article presents the integrated safety and tolerability of fentanyl ITS using data pooled from these studies...
  29. ncbi The addition of antiemetics to the morphine solution in patient controlled analgesia syringes used by children after an appendicectomy does not reduce the incidence of postoperative nausea and vomiting
    F J Munro
    Glasgow Royal Infirmary, Glasgow, UK
    Paediatr Anaesth 12:600-3. 2002
    ..01 mg.kg-1, followed by the same dose of the antiemetic agent added to the morphine solution during patient controlled analgesia (PCA) on the incidence of nausea and vomiting in children following an appendicectomy.
  30. ncbi A randomized trial of bupivicaine pain pumps to eliminate the need for patient controlled analgesia pumps in primary laparoscopic Roux-en-Y gastric bypass
    Daniel R Cottam
    Surgical Weight Control Center, Las Vegas, NV 89107, USA
    Obes Surg 17:595-600. 2007
    ..has previously been reported to lower costs to hospitals, while providing similar pain relief to opioid-based patient controlled analgesia (PCA) pumps. However, these benefits have not been investigated in laparoscopic bariatric surgery.
  31. ncbi The safety and efficacy of fentanyl iontophoretic transdermal system compared with morphine intravenous patient-controlled analgesia for postoperative pain management: an analysis of pooled data from three randomized, active-controlled clinical studies
    Eugene R Viscusi
    Department of Anesthesiology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Anesth Analg 105:1428-36, table of contents. 2007
    ..Postoperative pain is often managed using IV patient-controlled analgesia (PCA). In this analysis of pooled data, we compared the safety and efficacy of the fentanyl iontophoretic transdermal system (ITS) with morphine IV PCA...
  32. ncbi Intraoperative infusion of dexmedetomidine reduces perioperative analgesic requirements
    Alp Gurbet
    Department of Anesthesiology and Reanimation, Uludag University Faculty of Medicine, Bursa, Turkey
    Can J Anaesth 53:646-52. 2006
    ..Postoperative pain scores and morphine consumption were compared in a treated group and a placebo group, both of which received patient-controlled morphine after total abdominal hysterectomy...
  33. pmc The evolution of primary hyperalgesia in orthopedic surgery: quantitative sensory testing and clinical evaluation before and after total knee arthroplasty
    Valéria Martinez
    Department of Anesthesia, Assistance Publique Hopitaux de Paris, Hopital Raymond Poincare, Garches, France
    Anesth Analg 105:815-21. 2007
    ..Quantitative sensory testing (QST) allows precise characterization of sensory deficits and painful symptoms and may offer additional information on the pathophysiology of postoperative pain...
  34. ncbi Patient-controlled regional analgesia (PCRA) with ropivacaine after arthroscopic subacromial decompression
    K Axelsson
    Departments of Anaesthesiology and Intensive Care, University Hospital, Orebro, Sweden
    Acta Anaesthesiol Scand 47:993-1000. 2003
    ..The aim of the study was to evaluate postoperative analgesia and safety of wound instillation of ropivacaine either by a single dose or a patient-controlled regional anaesthesia (PCRA) technique...
  35. ncbi Comparison of patient-controlled analgesia with and without a background infusion after appendicectomy in children
    Karamehmet Yildiz
    Consultant, Department of Anaesthesiology, Erciyes University Gevher Nesibe Hospital, Kayseri, Turkey
    Paediatr Anaesth 13:427-31. 2003
    ....
  36. ncbi An iontophoretic fentanyl patient-activated analgesic delivery system for postoperative pain: a double-blind, placebo-controlled trial
    Eugene R Viscusi
    Department of Anesthesiology, Jefferson Medical College, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA
    Anesth Analg 102:188-94. 2006
    ..Treatment-related adverse events were similar between groups. This study demonstrated the superiority of the iontophoretic fentanyl HCl PATS over placebo for acute postoperative pain management...
  37. ncbi Preoperative oral rofecoxib does not decrease postoperative pain or morphine consumption in patients after radical prostatectomy: a prospective, randomized, double-blinded, placebo-controlled trial
    J J Huang
    Department of Anesthesiology and Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Clin Anesth 13:94-7. 2001
    ..To evaluate the analgesic efficacy of the rofecoxib po before radical prostatectomy...
  38. ncbi The fentanyl HCl patient-controlled transdermal system (PCTS): an alternative to intravenous patient-controlled analgesia in the postoperative setting
    Raymond Sinatra
    Department of Anesthesiology, Yale New Haven Medical Center, New Haven, Connecticut 06520, USA
    Clin Pharmacokinet 44:1-6. 2005
    ..Clinical studies have shown that the fentanyl HCl PCTS is effective in the management of acute postoperative pain. These studies have also demonstrated that the system is safe and well tolerated by patients...
  39. ncbi Patient-controlled transdermal fentanyl hydrochloride vs intravenous morphine pump for postoperative pain: a randomized controlled trial
    Eugene R Viscusi
    Department of Anesthesiology, Thomas Jefferson University, Philadelphia, PA 19107, USA
    JAMA 291:1333-41. 2004
    ..The fentanyl hydrochloride patient-controlled transdermal system eliminates the need for venous access and complicated programming of pumps...
  40. ncbi Fentanyl HCl iontophoretic transdermal system versus intravenous morphine pump after gynecologic surgery
    Shireen Ahmad
    Department of Anesthesiology, Northwestern University Feinberg School of Medicine, 251 E Huron Street, F5 704, Chicago, IL 60611, USA
    Arch Gynecol Obstet 276:251-8. 2007
    ..To compare the efficacy and safety of fentanyl iontophoretic transdermal system (ITS) with morphine intravenous patient-controlled analgesia (IV PCA) for pain management following gynecologic surgery...
  41. ncbi Emerging techniques in the management of acute pain: epidural analgesia
    Eugene R Viscusi
    Department of Anesthesiology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107 5092, USA
    Anesth Analg 101:S23-9. 2005
    ..Data from recent clinical studies are presented...
  42. ncbi A118G single nucleotide polymorphism of human mu-opioid receptor gene influences pain perception and patient-controlled intravenous morphine consumption after intrathecal morphine for postcesarean analgesia
    Alex T Sia
    Department of Women s Anaesthesia, KK Women s and Children s Hospital, 100 Bukit Timah Road, Singapore
    Anesthesiology 109:520-6. 2008
    ..The purpose of this study was to investigate whether this polymorphism contributes to the variability in response to morphine for postcesarean analgesia...
  43. ncbi Intravenous administration of propacetamol reduces morphine consumption after spinal fusion surgery
    J Hernández-Palazón
    Department of Anesthesiology, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain
    Anesth Analg 92:1473-6. 2001
    ..05). This study demonstrates the usefulness of propacetamol as an adjunct to PCA morphine in the treatment of postoperative pain after spinal fusion...
  44. ncbi Patient-controlled analgesia with fentanyl provides effective analgesia for second trimester labour: a randomized controlled study
    Carmencita Castro
    Departments of Anesthesia, Nursing, and Obstetrics, Mount Sinai Hospital, Toronto, Ontario, Canada
    Can J Anaesth 50:1039-46. 2003
    ..To examine dose and lockout intervals for effective fentanyl patient-controlled analgesia (PCA) in second trimester genetic termination of pregnancy, and compare three different fentanyl PCA regimes with morphine PCA...
  45. ncbi Analgesia after thoracotomy: epidural fentanyl/bupivacaine compared with intercostal nerve block plus intravenous morphine
    Mario Concha
    Department of Anesthesiology, Division of Surgery, Pontificia Universidad Catolica de Chile, Santiago, Chile
    J Cardiothorac Vasc Anesth 18:322-6. 2004
    ..The objective of this randomized study was to compare the quality of analgesia and lung function in 2 groups of patients undergoing pulmonary surgery through a posterolateral thoracotomy...
  46. ncbi Improving the analgesic efficacy of intrathecal morphine with parecoxib after total abdominal hysterectomy
    Supranee Niruthisard
    Department of Anesthesiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
    Anesth Analg 105:822-4. 2007
    ..The addition of parecoxib to intrathecal morphine and bupivacaine may improve analgesia and reduce morphine's opioid-related side effects...
  47. ncbi Intraperitoneal application of bupivacaine plus morphine for pain relief after laparoscopic cholecystectomy
    J Hernández-Palazón
    Department of Anaesthesia, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain
    Eur J Anaesthesiol 20:891-6. 2003
    ..This study was aimed at assessing the analgesic effect of the intraperitoneal administration of bupivacaine and morphine in patients undergoing laparoscopic cholecystectomy...
  48. ncbi Epidural infusion of levobupivacaine and sufentanil following thoracotomy
    G De Cosmo
    Department of Anaesthesiology and Intensive Care, Policlinico Universitario A Gemelli, Rome, Italy
    Anaesthesia 62:994-9. 2007
    ..05). Total morphine consumption and requests number was lower in group A (p < 0.05). Better pain relief was achieved using epidural 0.125% levobupivacaine...
  49. ncbi [The effects of patient-controlled epidural analgesia with background infusion after abdominal surgery]
    Masanori Yamauchi
    Department of Anesthesia, Oji General Hospital, Tomakomai, 053 8506
    Masui 53:29-33. 2004
    ..We evaluated the effects of PCEA with background infusion after major abdominal surgery...
  50. ncbi A comparison of multimodal perioperative analgesia to epidural pain management after gastric bypass surgery
    Roman Schumann
    Department of Anesthesia, Tufts New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Anesth Analg 96:469-74, table of contents. 2003
    ..In responders, infiltration analgesia as part of a multimodal regimen offers a simple, safe, and inexpensive alternative to epidural pain control...
  51. ncbi Obturator versus femoral nerve block for analgesia after total knee arthroplasty
    Ken Kardash
    Department of Anesthesia, Jewish General Hospital, McGill University, Montreal, Canada
    Anesth Analg 105:853-8. 2007
    ..Both femoral and obturator nerve blocks have been suggested to be useful in relieving pain after total knee arthroplasty (TKA). We sought to compare their efficacy...
  52. ncbi Ultra-fast-track anesthesia in off-pump coronary artery bypass grafting: a prospective audit comparing opioid-based anesthesia vs thoracic epidural-based anesthesia
    Thomas M Hemmerling
    Department of Anesthesiology, Centre Hospitalier de l Universite de Montreal, Hotel Dieu, Universite de Montreal, Montreal, Quebec, Canada
    Can J Anaesth 51:163-8. 2004
    ....
  53. ncbi Iliac crest donor site analgesia with ropivacaine infusion after autogenous bone graft
    J M Bonvini
    Eur J Anaesthesiol 21:239-41. 2004
  54. ncbi Postoperative analgesia after total-hip arthroplasty: Comparison of intravenous patient-controlled analgesia with morphine and single injection of femoral nerve or psoas compartment block. a prospective, randomized, double-blind study
    Philippe Biboulet
    Department of Anesthesiology and Critical Care, Centre Hospitalo Universitaire de Montpellier, Montpellier, France
    Reg Anesth Pain Med 29:102-9. 2004
    ..The authors compared the analgesic effects and quality of rehabilitation of three analgesic techniques after total-hip arthroplasty in a double-blind, randomized trial...
  55. ncbi Continuous interscalene infusion and single injection using levobupivacaine for analgesia after surgery of the shoulder. A double-blind, randomised controlled trial
    J Kean
    Department of Orthopaedic and Trauma Surgery, Ninewells Hospital and Medical School, TORT Building, Dundee DD1 9SY, UK
    J Bone Joint Surg Br 88:1173-7. 2006
    ..Our study has shown that continuous interscalene infusion of levobupivacaine is an effective method of post-operative analgesia after major surgery of the shoulder...
  56. ncbi Cost-effectiveness of thoracic patient-controlled epidural analgesia using bupivacaine with fentanyl vs bupivacaine with morphine after thoracotomy and upper abdominal surgery
    Songyos Valairucha
    Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    J Med Assoc Thai 88:921-7. 2005
    ..To compare the effectiveness and cost of thoracic patient-controlled epidural analgesia (TPCEA) using bupivacaine with fentanyl (BF) vs bupivacaine with morphine (BM) solution...
  57. ncbi Superiority of postoperative epidural over intravenous patient-controlled analgesia in orthopedic oncologic patients
    Avi A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Surgery 138:869-76. 2005
    ..Surgery for bone malignancy is associated with intense postoperative pain. Patient-controlled epidural analgesia (PCEA) and intravenous patient-controlled analgesia (IV-PCA) are used currently for postoperative pain control...
  58. ncbi Thoracic epidural versus intravenous patient-controlled analgesia after cardiac surgery: a randomized controlled trial on length of hospital stay and patient-perceived quality of recovery
    Vigdis Hansdottir
    Department of Cardiothoracic Anesthesia and Intensive Care, Sahlgrenska University Hospital, Goteborg, Sweden
    Anesthesiology 104:142-51. 2006
    ....
  59. ncbi Randomized, double-blind comparison of patient-controlled epidural infusion vs nurse-administered epidural infusion for postoperative analgesia in patients undergoing colonic resection
    J J Nightingale
    Department of Anaesthesia, Queen Alexandra Hospital, Cosham, Portsmouth, UK
    Br J Anaesth 98:380-4. 2007
    ..125% and fentanyl 4 microg ml(-1) administered by either PCEA with a background infusion or nurse-administered continuous epidural infusion (CEI) after major intra-abdominal surgery...
  60. ncbi Single-dose extended-release epidural morphine for pain following hip arthroplasty
    Eugene R Viscusi
    Department of Anesthesiology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Am J Ther 13:423-31. 2006
    ..Safety results were similar between groups. Single-dose EREM was generally safe and effective for treating postoperative pain and reduced the need for supplemental analgesia...
  61. ncbi The superficial cervical plexus block for postoperative pain therapy in carotid artery surgery. A prospective randomised controlled trial
    M Messner
    Department of Anesthesiology, Friedrich Alexander Universitat, Erlangen, Germany
    Eur J Vasc Endovasc Surg 33:50-4. 2007
    ..Use of opioids can mask neurological deficits. We investigated whether superficial cervical plexus block reduced postoperative opioid consumption after carotid endarterectomy...
  62. ncbi Comparison of the effects of thoracic epidural analgesia and i.v. infusion with lidocaine on cytokine response, postoperative pain and bowel function in patients undergoing colonic surgery
    C P Kuo
    Department of Anesthesiology Taipei, Tri Service General Hospital, Taiwan
    Br J Anaesth 97:640-6. 2006
    ..v. lidocaine were able to decrease postoperative pain and duration of ileus. We compared TEA and i.v. lidocaine (IV) regarding their effects on cytokines, pain and bowel function after colonic surgery...
  63. ncbi Low vs. high concentration of levobupivacaine for post-operative epidural analgesia: influence of mode of delivery
    M Dernedde
    Department of Anaesthesiology, University Hospital Centre, Charleroi, Belgium
    Acta Anaesthesiol Scand 50:613-21. 2006
    ..This prospective study evaluated the influence of two concentrations of levobupivacaine on the quality of analgesia in two modes of delivery after lower abdominal surgery...
  64. ncbi [Effectiveness of clonidine and fentanyl addition to bupivacaine in postoperative patient controlled epidural analgesia]
    I Topcu
    Arzt für Anästhesie, Celal Bayar Universität, Medizinische Fakultat, Abteilung Anästhesiologie
    Anasthesiol Intensivmed Notfallmed Schmerzther 40:521-5. 2005
    ....
  65. ncbi Postoperative extradural analgesia with morphine and ropivacaine. A double-blind comparison between placebo and ropivacaine 10 mg/h or 16 mg/h
    K Axelsson
    Department of Anesthesiology and Intensive Care, Orebro University Hospital, Orebro, Sweden
    Acta Anaesthesiol Scand 49:1191-9. 2005
    ..The aim of this study was to compare the epidural vs. PCA technique and high-dose vs. low-dose ropivacaine combined with morphine during knee replacement surgery...
  66. ncbi Peridural methylprednisolone and wound infiltration with bupivacaine for postoperative pain control after posterior lumbar spine surgery: a randomized double-blinded placebo-controlled trial
    Kitti Jirarattanaphochai
    Department of Orthopaedic, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Spine (Phila Pa 1976) 32:609-16; discussion 617. 2007
    ..A randomized, double-blind placebo controlled trial in multimodal analgesia for postoperative pain was conducted...
  67. ncbi Spread of subarachnoid block, intraoperative local anaesthetic requirements and postoperative analgesic requirements in Caesarean section and total abdominal hysterectomy
    A Fassoulaki
    Department of Anaesthesiology, Aretaieion Hospital, Medical School, University of Athens, 76 Vassilissis Sofias Avenue, Athens 11528, Greece
    Br J Anaesth 93:678-82. 2004
    ..The study was designed to assess the spread of subarachnoid block and the intra- and postoperative analgesic requirements in pregnant vs non-pregnant women...
  68. ncbi Combined intrathecal and epidural magnesium sulfate supplementation of spinal anesthesia to reduce post-operative analgesic requirements: a prospective, randomized, double-blind, controlled trial in patients undergoing major orthopedic surgery
    R Arcioni
    Department of Anesthesia and Intensive Care Medicine, La Sapienza University of Rome, II Faculty of Medicine, S Andrea Hospital, Rome, Italy
    Acta Anaesthesiol Scand 51:482-9. 2007
    ..We investigated whether supplementation of spinal anesthesia with combined intrathecally and epidurally infused MgSO(4) reduced patients' post-operative analgesia requirements...
  69. ncbi The postoperative analgesic efficacy of wound instillation with ropivacaine 0.1% versus ropivacaine 0.2%
    Edna Zohar
    Department of Anesthesiology and Intensive Care, Meir Hospital, Kfar Saba, Israel
    J Clin Anesth 16:399-404. 2004
    ..To assess the influence of ropivacaine concentration on wound instillation-induced postoperative analgesia following total abdominal hysterectomy with bilateral salpingo-oophorectomy...
  70. ncbi The effect of epidural vs intravenous analgesia for posterior spinal fusion surgery
    Jerome F O'Hara
    Department of General Anesthesiology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Paediatr Anaesth 14:1009-15. 2004
    ..The study objective was to compare epidural vs intravenous postoperative analgesia in posterior spinal fusion surgery patients...
  71. ncbi Comparison of postoperative pain management techniques on endocrine response to surgery: a randomised controlled trial
    Israel Z Yardeni
    Department of Anaesthesiology, Rabin Medical Center, Golda Hasharon Campus, Petah Tiqva 49372, affiliated with the Sackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel
    Int J Surg 5:239-43. 2007
    ..7, 15.7 ng/mL) compared with PCA (24.9, 17.1) group. The present results indicate that the PCEA technique offers an advantageous treatment associated with reduced postoperative pain, and attenuated neuroendocrine response...
  72. ncbi Fentanyl and clonidine as adjunctive analgesics with levobupivacaine in paravertebral analgesia for breast surgery
    C L Burlacu
    Department of Anaesthesia, Intensive Care and Pain Medicine, Mater Misericordiae University Hospital, Dublin, Ireland
    Anaesthesia 61:932-7. 2006
    ..All groups received postoperative i.v. morphine patient controlled analgesia (PCA). Although mean (SD) postoperative PCA morphine consumption was decreased in LF [7.9 (4...
  73. ncbi A randomized controlled trial of the anticatabolic effect of epidural analgesia and hypocaloric glucose
    Ralph Lattermann
    Department of Anesthesia, Royal Victoria Hospital, McGill University, Montreal, Quebec, Canada
    Reg Anesth Pain Med 32:227-32. 2007
    ..The goal of the present study was to investigate whether epidural analgesia exerts a protein-sparing effect after colorectal surgery in the presence of hypocaloric glucose supply initiated with surgical skin incision...
  74. ncbi [The comparison of the effects and side effects of local anesthetic and opioid combinations in epidural patient controlled analgesia]
    Zeynep Eti
    Marmara University Faculty of Medicine, Department of Anesthesiology, Istanbul, Turkey
    Agri 17:34-9. 2005
    ....
  75. ncbi [Comparison of bupivacaine-fentanyl versus bupivacaine-morphine for patient controlled epidural analgesia]
    Yavuz Gurkan
    Kocaeli University Faculty Medicine, Department of Anesthesiology, Istanbul, Turkey
    Agri 17:40-3. 2005
    ..The incidence of pruritus was higher in Group BM than Group BF (p<0.05). Both treatment modalities provided adequate postoperative analgesia, but the risk of respiratory depression with opioid use should be considered...
  76. ncbi Oral oxycodone hydrochloride versus epidural anaesthesia for pain control after radical retropubic prostatectomy
    Lena Hohwü
    Department of Urology, Karolinska University Hospital, Stockholm, Sweden
    Scand J Urol Nephrol 40:192-7. 2006
    ....
  77. ncbi Post-thoracotomy pain after thoracic epidural analgesia: a prospective follow-up study
    E Tiippana
    Department of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Acta Anaesthesiol Scand 47:433-8. 2003
    ..We wanted to find out if active use of TEA, combined with extended pain management at home, reduces the incidence of chronic post-thoracotomy pain...
  78. ncbi Epinephrine markedly improves thoracic epidural analgesia produced by a small-dose infusion of ropivacaine, fentanyl, and epinephrine after major thoracic or abdominal surgery: a randomized, double-blinded crossover study with and without epinephrine
    Geir Niemi
    Department of Anesthesiology, Rikshospitalet University Hospital, University of Oslo, N 0027 Oslo, Norway
    Anesth Analg 94:1598-605, table of contents. 2002
    ..We conclude that epinephrine improves the pain relief and reduces the side effects of a thoracic epidural infusion of ropivacaine and fentanyl after major thoracic or upper abdominal surgery...
  79. ncbi Dextromethorphan reduces immediate and late postoperative analgesic requirements and improves patients' subjective scorings after epidural lidocaine and general anesthesia
    Avi A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel
    Anesth Analg 94:1547-52. 2002
    ..Subjectively scored levels of pain, sedation, and well-being were better as well...
  80. ncbi Efficacy of ropivacaine compared with ropivacaine plus sufentanil for postoperative analgesia after major knee surgery
    C Lorenzini
    Faculdade de Medicina, São Vicente de Paulo University Hospital, University de Passo Fundo UPF RS, Rua Teixeira Soares, 808 99010 901 Passo Fundo RS, Brazil
    Anaesthesia 57:424-8. 2002
    ..The differences were more pronounced 12 h after the beginning of the analgesic schedule. This study failed to demonstrate any worthwhile clinical benefit from the addition of sufentanil...
  81. ncbi Cost-effectiveness of analgesia after Caesarean section. A comparison of intrathecal morphine and epidural PCA
    M Vercauteren
    Department of Anesthesia, University Hospital Antwerp, Edegem, Belgium
    Acta Anaesthesiol Scand 46:85-9. 2002
    ..Patient-controlled analgesia (PCA) techniques and intrathecal morphine are the most widely used treatments for post-Caesarean section pain. However these methods have not been compared with respect to analgesic quality and cost differences...
  82. ncbi Postoperative analgesia by epidural methylprednisolone after posterolateral thoracotomy
    Y Blanloeil
    , , CHU Nantes, France
    Br J Anaesth 87:635-8. 2001
    ..No side effects were reported. It was concluded in this small study that these results did not support the use of epidural steroids for postoperative analgesia after PLT...
  83. ncbi The efficacy and safety of three concentrations of levobupivacaine administered as a continuous epidural infusion in patients undergoing orthopedic surgery
    John A C Murdoch
    Department of Anaesthesia, HCI International Medical Centre, Clydebank, Scotland
    Anesth Analg 94:438-44, table of contents. 2002
    ..25% concentration provided significantly longer analgesia than 0.125% or 0.0625% levobupivacaine without any significant increase in detectable motor blockade relative to the 0.125% group...
  84. ncbi Epidural administration of low-dose morphine combined with clonidine for postoperative analgesia after lumbar disc surgery
    Vincent Bonhomme
    University Department of Anesthesia and Intensive Care Medicine, CHR de la Citadelle, Liege University Hospital, Liege, Belgium
    J Neurosurg Anesthesiol 14:1-6. 2002
    ..The excellent analgesic conditions were obtained at the expense of a higher incidence of difficulties in initiating micturition...
  85. ncbi The effect of preoperative epidural morphine on postoperative analgesia in children
    F Kiffer
    Department of Anesthesiology and Surgical Intensive Care 2, , Rennes, France
    Anesth Analg 93:598-600. 2001
    ..Twenty-one children older than 6 yr scheduled for major surgery were randomly assigned to two groups, a control group and an epidural group that received a single epidural morphine injection...
  86. ncbi Postoperative analgesia by combined continuous infusion and patient-controlled epidural analgesia (PCEA) following hip replacement: ropivacaine versus bupivacaine
    L Bertini
    Department of Anaesthesia and ICU, Centro Traumatologico Ortopedico, Rome, Italy
    Acta Anaesthesiol Scand 45:782-5. 2001
    ..CONCLUSIONS: Despite similar analgesic effects, epidural infusion of ropivacaine combined with PCEA provides higher patient satisfaction than equal doses of bupivacaine due to lack of motor block...
  87. ncbi A comparison of ropivacaine with fentanyl to bupivacaine with fentanyl for postoperative patient-controlled epidural analgesia
    P S Hodgson
    Departments of Anesthesiology, Virginia Mason Medical Center, Seattle, WA 98111, USA
    Anesth Analg 92:1024-8. 2001
    ..05% or 0.1% solutions are clinically similar. Lower-extremity motor function will decrease with the use of any of these combinations, but is unlikely to result in the inability to walk...
  88. ncbi A comparison of 0.1% and 0.2% ropivacaine and bupivacaine combined with morphine for postoperative patient-controlled epidural analgesia after major abdominal surgery
    Marc Senard
    Department of Anesthesia and Intensive Care Medicine, CHU de Liege, Domaine du Sart Tilman, Belgium
    Anesth Analg 95:444-9, table of contents. 2002
    ..1% or 0.2% solution of ROPI or BUPI combined with epidural morphine resulted in comparable analgesia. As compared with ROPI 0.1%, the use of ROPI 0.2% increased consumption of local anesthetic without improving analgesia...
  89. ncbi Intrathecal morphine in anesthesia for cesarean delivery: dose-response relationship for combinations of low-dose intrathecal morphine and spinal bupivacaine
    Nermin K Girgin
    Faculty of Medicine, Department of Anesthesiology and Reanimation, Uludag University, Bursa 16059, Turkey
    J Clin Anesth 20:180-5. 2008
    ..To evaluate the quality of analgesia and the severity of side effects of intrathecal morphine administered for a dose range of 0.0 to 0.4 mg for postcesarean analgesia with low-dose bupivacaine...
  90. ncbi The minimally effective concentration of adrenaline in a low-concentration thoracic epidural analgesic infusion of bupivacaine, fentanyl and adrenaline after major surgery. A randomized, double-blind, dose-finding study
    G Niemi
    Department of Anaesthesiology, Rikshospitalet University Hospital, Oslo, Norway
    Acta Anaesthesiol Scand 47:439-50. 2003
    ..ml- 1. Concern about possible adverse effects on spinal cord blood flow, expressed by others, prompted us to find the lowest concentration of adrenaline needed to produce effective and reliable pain relief after major surgery...
  91. ncbi Pain relief and safety after major surgery. A prospective study of epidural and intravenous analgesia in 2696 patients
    P Flisberg
    Department of Anesthesiology and Intensive Care, Lund University Hospital, Lund, Sweden
    Acta Anaesthesiol Scand 47:457-65. 2003
    ..The aim was to investigate efficacy, adverse effects and safety of the treatments in a large patient population...
  92. ncbi The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial
    John G McDonnell
    Department of Anaesthesia, Clinical Sciences Institute, Centre for Pain Research, National University of Ireland, Galway, Ireland
    Anesth Analg 106:186-91, table of contents. 2008
    ..We evaluated its analgesic efficacy over the first 48 postoperative hours after cesarean delivery performed through a Pfannensteil incision, in a randomized controlled, double-blind, clinical trial...
  93. ncbi Intraarticular administration of ketorolac, morphine, and ropivacaine combined with intraarticular patient-controlled regional analgesia for pain relief after shoulder surgery: a randomized, double-blind study
    Kjell Axelsson
    Division of Anesthesiology and Intensive Care and Division of Orthopedics, Department of Medicine, Orebro University Hospital, Orebro, Sweden
    Anesth Analg 106:328-33, table of contents. 2008
    ..In this study we assessed the efficacy of intraarticular regional analgesia on postoperative pain and analgesic requirements...
  94. ncbi Intrathecal clonidine added to a bupivacaine-morphine spinal anesthetic improves postoperative analgesia for total knee arthroplasty
    Brian D Sites
    Departments of Anesthesiology, Dartmouth Medical School, Dartmouth Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03756, USA
    Anesth Analg 96:1083-8, table of contents. 2003
    ..We conclude that the coadministration of intrathecal clonidine and morphine decreases the 24-h IV morphine consumption and improves the 24-h VAS score when compared with intrathecal morphine alone...
  95. ncbi Postoperative morphine use and hyperalgesia are reduced by preoperative but not intraoperative epidural analgesia: implications for preemptive analgesia and the prevention of central sensitization
    Joel Katz
    Department of Psychology and School of Kinesiology and Health Science, York University, Toronto, Ontario, Canada
    Anesthesiology 98:1449-60. 2003
    ....
  96. ncbi Postoperative epidural analgesia after total knee arthroplasty with sufentanil 1 microg/ml combined with ropivacaine 0.2%, ropivacaine 0.125%, or levobupivacaine 0.125%: a randomized, double-blind comparison
    Elske Sitsen
    Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands
    Reg Anesth Pain Med 32:475-80. 2007
    ..2% and 0.125%) and levobupivacaine (0.125%), all in combination with sufentanil 1 microg/mL with regard to postoperative pain relief and absence of motor block in a patient-controlled epidural analgesia setting...
  97. ncbi Disposition and clinical outcome after intraperitoneal meperidine and ropivacaine administration during laparoscopic surgery
    Michael J Paech
    Pharmacology and Anaesthesiology Unit, School of Medicine and Pharmacology, The University of Western Australia, Perth, Western Australia, Australia
    Anesth Analg 106:278-86, table of contents. 2008
    ..The null hypothesis was that there was no significant difference among groups for dynamic pain in the first 24 h after major abdominal laparoscopic surgery...
  98. ncbi [Continuous monitoring of spontaneous respiration in the postoperative phase. 4. The effect of postoperative pain therapy on cutaneous oxygen and carbon dioxide partial pressure following gynecologic surgery with neuroleptanalgesia]
    K A Lehmann
    Institut für Anaesthesiologie und Operative Intensivmedizin, Universitat zu Koln
    Anaesthesist 42:441-7. 1993
    ..Groups were compared by means of the chi-square test, Student's t-test or analysis of variance (level of significance, P < or = 0.05)...
  99. ncbi Double-masked randomized trial comparing alternate combinations of intraoperative anesthesia and postoperative analgesia in abdominal aortic surgery
    E J Norris
    Department of Anesthesia and Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 8711, USA
    Anesthesiology 95:1054-67. 2001
    ....
  100. ncbi [Motor function during patient-controlled analgesia via a lumbar epidural catheter after major abdominal surgery. Ropivacaine-sufentanil vs. bupivacaine-sufentanil]
    L H J Eberhart
    Universitätsklinik für Anästhesie und Intensivtherapie Philipps Universität Marburg
    Anasthesiol Intensivmed Notfallmed Schmerzther 37:216-21. 2002
    ..The aim of the present study was to investigate postoperative motoric impairment during patient-controlled analgesia after major abdominal surgery with ropivacaine-sufentanil and bupivacaine-sufentanil via a lumbar epidural catheter...
  101. pmc The effect of transdermal scopolamine plus intravenous dexamethasone for the prevention of postoperative nausea and vomiting in patients with epidural PCA after major orthopedic surgery
    Hyun Kyu Lee
    Department of Anesthesia and Pain Medicine, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea
    Korean J Anesthesiol 58:50-5. 2010
    ....

Research Grants27

  1. Testing the feasibility of patient-controlled sedation in ventilated ICU patients
    Craig R Weinert; Fiscal Year: 2013
    ..Demonstrating the safety and feasibility of patient-controlled sedation in this patient population has the potential to positively impact outcomes for thousands of mechanically ventilated ICU patients each year in the U.S. ..
  2. Gated Carbon Nanotube Membrane Transdermal Drug Delivery
    BRUCE JACKSON HINDS; Fiscal Year: 2013
    ..Transdermal fentanyl therapy could be improved by allowing a flexible dosage regimen for noninvasive patient controlled analgesia with added safety and security features...
  3. Effectiveness and Feasibility of Patient Controlled Analgesia in the ED
    ADRIENNE JEANNE BIRNBAUM; Fiscal Year: 2013
    ..b>Patient controlled analgesia (PCA) has the potential to allow ED patients to actively participate in pain management by allowing ..
  4. BEHAVIORAL EFFECTS OF OPIOIDS IN VOLUNTEERS
    James Zacny; Fiscal Year: 2003
    ..We propose to utilize a patient controlled analgesia (PCA) methodology to examine the degree to which four different opioids- morphine, meperidine, ..
  5. Safety and Efficacy of Patient Controlled Analgesia in the Emergency Department
    Polly Bijur; Fiscal Year: 2009
    ..b>Patient Controlled Analgesia (PCA) has been used successfully in post-operative pain management...
  6. Cocaine, Disulfiram & DBH: A Pharmacomechanistic Study
    Robert Malison; Fiscal Year: 2004
    ..abstract_text> ..
  7. Response to Morphine in Children with SC Disease
    Eufemia Jacob; Fiscal Year: 2007
    ..Morphine via patient controlled analgesia is widely used in hospital settings to manage severe pain in SCD...
  8. AGING AND PERIOPERATIVE OUTCOMES
    JACQUELINE LEUNG; Fiscal Year: 2005
    ..We believe that our studies will provide important results contributing ultimately to the improvement of perioperative outcomes in geriatric patients. ..
  9. Effects of Opioids on Sleep and Fatigue
    Joel Dimsdale; Fiscal Year: 2004
    ..abstract_text> ..
  10. Sleep Apnea and Hypertension: Role of SNS
    Joel Dimsdale; Fiscal Year: 2008
    ....
  11. Biobehavioral Effects of Yoga During Cancer Treatment
    Lorenzo Cohen; Fiscal Year: 2007
    ..abstract_text> ..
  12. PRESURGICAL STRESS REDUCTION MENTAL HEALTH AND CANCER
    Lorenzo Cohen; Fiscal Year: 2002
    ..We hypothesize that pre-surgical stress management will reduce the negative impact of RP assessed by psychological, physiological, and quality of life measures. ..
  13. Nursing Home IT: Optimal Medication and Care Delivery
    Susan Horn; Fiscal Year: 2006
    ..Distill and summarize lessons learned about what is critical for successful implementation of HIT in nursing homes, including facilitators, barriers, and strategies to address them. ..
  14. Biobehavioral Effects of Emotional Expression in Cancer
    Lorenzo Cohen; Fiscal Year: 2006
    ..The effects of the intervention should be evident throughout recovery and across indices of quality of life, mental health, subjective symptoms of stress, and immune function. ..
  15. STRESS, BLOOD PRESSURE AND ETHNICITY
    Joel E Dimsdale; Fiscal Year: 2010
    ..The study scrutinizes sleep, inflammation, vasodilation, autonomic functioning, and baroreflex regulation. We hypothesize that adversity has a stronger impact on cardiovascular pathophysiology than does ethnicity. ..
  16. TMS in the Management of Postoperative Pain
    Jeffrey J Borckardt; Fiscal Year: 2010
    ..Thus, new interventions that have the potential to reduce reliance on postoperative morphine in this patient population such as TMS need to be explored. ..
  17. Burden of Obstructive Sleep Apnea in Stroke (BOSAST)
    Joel E Dimsdale; Fiscal Year: 2010
    ..Obstructive sleep apnea has similar symptoms and is also very common in stroke patients. This study will determine if treating apnea in stroke patients will improve these burdens. ..
  18. Beta2 adrenoceptor genotype and preterm labor
    Richard Smiley; Fiscal Year: 2009
    ..abstract_text> ..
  19. Photodynamic Therapy for the Treatment of Obstructive E*
    Todd Demmy; Fiscal Year: 2007
    ..This proposal will be instrumental in the development of a novel PDT drug without long-term restrictions of patients' sun exposure. [unreadable] [unreadable]..
  20. Neural blockade with vanilloids
    Igor Kissin; Fiscal Year: 2007
    ..To study the specific aims of the project the effects of RTX will be examined in rats by behavioral methods; and whole cell voltage-clamp technique will be used to identify a mechanism for impulse failure induced by RTX. ..
  21. Pain Assessment in Cognitively Impaired Children
    Shobha Malviya; Fiscal Year: 2005
    ..A reliable and valid pain assessment tool is critical to facilitate our future study of pain management strategies in these children. ..
  22. International Center of TCM for Cancer
    Lorenzo Cohen; Fiscal Year: 2004
    ....
  23. Supplementing Relaxation & Music for Postoperative Pain
    Marion Good; Fiscal Year: 2004
    ..Knowledge of the effects of patient teaching and non-invasive methods to reduce post-operative pain, stress, and immune function may facilitate postoperative recovery with lower health-care cost. ..
  24. COMPUTER AIDED STRESS REDUCTION, MENTAL HEALTH & CANCER
    Lorenzo Cohen; Fiscal Year: 2002
    ....
  25. ACUTE TOLERANCE IN ANESTHETIC ACTIONS AND INTERACTIONS
    Igor Kissin; Fiscal Year: 2001
    ....
  26. Role of the Amygdala in Opioid Self-administration in Rats with Chronic Pain.
    Thomas Martin; Fiscal Year: 2009
    ....