bisphenol a glycidyl methacrylate

Summary

Summary: The reaction product of bisphenol A and glycidyl methacrylate that undergoes polymerization when exposed to ultraviolet light or mixed with a catalyst. It is used as a bond implant material and as the resin component of dental sealants and composite restorative materials.

Top Publications

  1. ncbi Effect of a sodium hypochlorite gel on dentin bonding
    J Perdigao
    Division of Operative Dentistry, University of Minnesota, Minneapolis, MN, USA
    Dent Mater 16:311-23. 2000
  2. ncbi Mechanical properties of resin cements with different activation modes
    R R Braga
    Department of Dental Materials, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil
    J Oral Rehabil 29:257-62. 2002
  3. ncbi Resistance to fracture of endodontically treated teeth restored with different post systems
    Begum Akkayan
    Departmentof Prosthtic Dentistry, Faculty of Dentistry, University of Istanbul, Turkey
    J Prosthet Dent 87:431-7. 2002
  4. ncbi Comparison of in vivo and in vitro shear bond strength
    Stephen D Murray
    Department of Orthodontics, Sunderland Royal Hospital, Sunderland, United Kingdom
    Am J Orthod Dentofacial Orthop 123:2-9. 2003
  5. ncbi Microtensile bond strength between adhesive cements and root canal dentin
    Serge Bouillaguet
    Department of Cariology, Endodontics and Pediatric Dentistry, School of Dental Medecine, University of Geneva, 19 Rue BarthElemy Menn, CH 1205, Geneva, Switzerland
    Dent Mater 19:199-205. 2003
  6. doi Degree of conversion of resin blends in relation to ethanol content and hydrophilicity
    Milena Cadenaro
    Department of Biomedicine, Unit of Dental Sciences and Biomaterials, University of Trieste, Via Stuparich 1, I 34125 Trieste, Italy
    Dent Mater 24:1194-200. 2008
  7. ncbi Cytotoxicity of bisphenol A glycidyl methacrylate on cytochrome P450-producing cells
    S Hikage
    Department of Fixed Prosthodontics, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu cho, Ishikari gun, Japan
    J Oral Rehabil 30:544-9. 2003
  8. ncbi Stability of dentin bond strengths using different bonding techniques after 12 months: total-etch, deproteinization and self-etching
    Luiz Andre Freire Pimenta
    Department of Restorative Dentistry, School of Dentistry of Piracicaba, University of Campinas, Piracicaba, Brazil
    Oper Dent 29:592-8. 2004
  9. ncbi Shear bond strength with increasing light-guide distance from dentin
    Xiaoming Xu
    Department of Operative Dentistry and Biomaterials, Louisiana State University Health Sciences Center School of Dentistry, New Orleans 70119, USA
    J Esthet Restor Dent 18:19-27; discussion 28. 2006
  10. ncbi Influence of fiber-post translucency on the degree of conversion of a dual-cured resin cement
    André Luis Faria e Silva
    Restorative Dentistry Department, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil
    J Endod 33:303-5. 2007

Research Grants

  1. SPEAKER TRAVEL AND SCIENTIFIC SESSION SUPPORT FOR THE TERATOLOGY SOCIETY 50TH
    Christina Chambers; Fiscal Year: 2011
  2. Epigenomic Events in Development of the Locus Coeruleus Noradrenergic Neurons
    Jan Krzysztof Blusztajn; Fiscal Year: 2012
  3. Robert L Nussbaum; Fiscal Year: 2014
  4. FUNCTIONAL PROPERTIES OF HEMOGLOBINS AND MYOGLOBINS
    John S Olson; Fiscal Year: 2010
  5. Mechanisms for Cardiovascular Effects of air pollutants: Effect of Age and Sex
    BRITT HOLMEN; Fiscal Year: 2010
  6. Nicola C Partridge; Fiscal Year: 2016
  7. Evaluation of novel FoxM1 inhibitors against liver cancer
    Andrei L Gartel; Fiscal Year: 2012
  8. Novel Small Molecule Therapeutics to Treat Obesity
    SUSAN MEDGHALCHI; Fiscal Year: 2010
  9. Beverly H Koller; Fiscal Year: 2014
  10. Kelly A Birdwell; Fiscal Year: 2015

Detail Information

Publications455 found, 100 shown here

  1. ncbi Effect of a sodium hypochlorite gel on dentin bonding
    J Perdigao
    Division of Operative Dentistry, University of Minnesota, Minneapolis, MN, USA
    Dent Mater 16:311-23. 2000
    ..To substantiate this hypothetical insignificance of the HL, sodium hypochlorite (NaOCl) has been used to remove collagen from etched dentin prior to bonding...
  2. ncbi Mechanical properties of resin cements with different activation modes
    R R Braga
    Department of Dental Materials, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil
    J Oral Rehabil 29:257-62. 2002
    ..g. filler content and monomer type) affect the flexural strength of composites. No statistical difference was detected in the flexural modulus among the different groups...
  3. ncbi Resistance to fracture of endodontically treated teeth restored with different post systems
    Begum Akkayan
    Departmentof Prosthtic Dentistry, Faculty of Dentistry, University of Istanbul, Turkey
    J Prosthet Dent 87:431-7. 2002
    ..Purpose. This in vitro study compared the effect of 1 titanium and 3 esthetic post systems on the fracture resistance and fracture patterns of crowned, endodontically treated teeth...
  4. ncbi Comparison of in vivo and in vitro shear bond strength
    Stephen D Murray
    Department of Orthodontics, Sunderland Royal Hospital, Sunderland, United Kingdom
    Am J Orthod Dentofacial Orthop 123:2-9. 2003
    ..96 MPa vs 13.61 MPa) than did the controls. These results indicate differences between bond strength testing in vitro and in vivo. Further research is required into the effects of the oral environment on bond strength...
  5. ncbi Microtensile bond strength between adhesive cements and root canal dentin
    Serge Bouillaguet
    Department of Cariology, Endodontics and Pediatric Dentistry, School of Dental Medecine, University of Geneva, 19 Rue BarthElemy Menn, CH 1205, Geneva, Switzerland
    Dent Mater 19:199-205. 2003
    ....
  6. doi Degree of conversion of resin blends in relation to ethanol content and hydrophilicity
    Milena Cadenaro
    Department of Biomedicine, Unit of Dental Sciences and Biomaterials, University of Trieste, Via Stuparich 1, I 34125 Trieste, Italy
    Dent Mater 24:1194-200. 2008
    ..The hypothesis tested was that extent of polymerization of resin blends is affected by resin hydrophilicity, solvent concentrations or time of polymerization...
  7. ncbi Cytotoxicity of bisphenol A glycidyl methacrylate on cytochrome P450-producing cells
    S Hikage
    Department of Fixed Prosthodontics, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu cho, Ishikari gun, Japan
    J Oral Rehabil 30:544-9. 2003
    ..Bisphenol A (BPA) and bisphenol A glycidyl methacrylate (Bis-GMA) and a positive control (Aflatoxine Bl) were added separately to each well and cultured for ..
  8. ncbi Stability of dentin bond strengths using different bonding techniques after 12 months: total-etch, deproteinization and self-etching
    Luiz Andre Freire Pimenta
    Department of Restorative Dentistry, School of Dentistry of Piracicaba, University of Campinas, Piracicaba, Brazil
    Oper Dent 29:592-8. 2004
    ..Single Bond applied after total-etch presented higher mean SBS when compared to the other surface treatment methods. Collagen removal negatively influenced SBS, and the experimental self-etching adhesive presented intermediate values...
  9. ncbi Shear bond strength with increasing light-guide distance from dentin
    Xiaoming Xu
    Department of Operative Dentistry and Biomaterials, Louisiana State University Health Sciences Center School of Dentistry, New Orleans 70119, USA
    J Esthet Restor Dent 18:19-27; discussion 28. 2006
    ..In Class II composite restorations, the adhesive covering the gingival floor of the deep cavity preparation is 2 to 8 mm from the light guide and may not be adequately cured with a typical 10-second curing time...
  10. ncbi Influence of fiber-post translucency on the degree of conversion of a dual-cured resin cement
    André Luis Faria e Silva
    Restorative Dentistry Department, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil
    J Endod 33:303-5. 2007
    ..Light-Post exhibited a higher degree of conversion than that of Aestheti-Post only at medium depth. Light-Post effectiveness regarding the degree of conversion is dependent on the depth...
  11. ncbi Tubular occlusion optimizes bonding of hydrophobic resins to dentin
    F T Sadek
    Department of Dental Materials, School of Dentistry, University of Sao Paulo, Brazil
    J Dent Res 86:524-8. 2007
    ..Minimal nanoleakage was identified within hybrid layers created in the oxalate- and PADC-pre-treated deep dentin. The use of tubular occluding agents optimized bonding of hydrophobic resins to dentin...
  12. ncbi Effects of a combined application of potassium oxalate gel/adhesive agent on dentin permeability in vitro
    Safira Marques de Andrade e Silva
    Department of Restorative Dentistry, University of Campinas, Piracicaba, Brazil
    J Adhes Dent 9:505-12. 2007
    ..To test the effects of sequential application of potassium oxalate gel/adhesive agent on in vitro dentin permeability...
  13. ncbi Bond strength to surface enamel for different tooth types
    R S Hobson
    Child Dental Health, Newcastle Dental School, Framlington Place, NE2 4BW, Newcastle upon Tyne, UK
    Dent Mater 17:184-9. 2001
    ..The aim of this study was to investigate the possible differences in bond strength to acid etched enamel on the different teeth of the dentition...
  14. ncbi Comparative bond strength of brackets cured using a pulsed xenon curing light with 2 different light-guide sizes
    Larry J Oesterle
    Department of Growth and Development, School of Dentistry, University of Colorado Health Sciences Center, Campus Box 2184, 4200 East 9th Avenue, Denver, CO 80262, USA
    Am J Orthod Dentofacial Orthop 122:242-50. 2002
    ..There appeared to be no advantage to the use of a pulsed xenon plasma arc light in bonding orthodontic brackets. Results from using either a small or a large light-guide tip varied with the adhesive tested...
  15. ncbi Influence of the direction of tubules on bond strength to dentin
    M Ogata
    Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, 5-45 Yushima 1-chome, Bunkyo-ku, Tokyo 113-8549, Japan
    Oper Dent 26:27-35. 2001
    ..The tensile bond strength of the group with tubules parallel to the bonded interface was higher than that of tubules cut perpendicularly. This tendency reached statistical significance using SB and OS...
  16. ncbi Comparative in vivo and in vitro investigation of interfacial bond variability
    M Hannig
    Department of Operative Dentistry and Periodontology, University of Freiburg, Hugstetter Strasse 55, D-79106 Freiburg, Germany
    Oper Dent 26:3-11. 2001
    ..It was concluded that achievement of a completely gap-free internal adaptation between restorative material and dentin in totally bonded composite resin restorations is difficult to predict under in vivo as well as in vitro conditions...
  17. ncbi Shear bond strength of four filled dentin bonding systems
    J R Gallo
    LSU School of Dentistry, 1100 Florida Ave, Box 137, New Orleans, LA 70124, USA
    Oper Dent 26:44-7. 2001
    ..The data were subjected to One-Factor ANOVA and Newman-Kuels post-hoc tests. Statistical analysis revealed that One Coat Bond had significantly greater shear bond strength than all other materials tested...
  18. ncbi Relationship between adhesive thickness and microtensile bond strength
    L Zheng
    Cariology and Operative Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, 5-45 Yushima, 1-chome, Bunkyo-ku, Tokyo 113-8549, Japan
    Oper Dent 26:97-104. 2001
    ..05). However, the bond strengths of the Single Bond decreased significantly with increased thickness of the bonding layer (p < 0.05)...
  19. ncbi "No-bottle" vs "multi-bottle" dentin adhesives--a microtensile bond strength and morphological study
    R Frankenberger
    Policlinic for Operative Dentistry and Periodontology, University of Erlangen-Nuremberg, Glueckstrasse 11, D-91054 Erlangen, Germany
    Dent Mater 17:373-80. 2001
    ..When applied in multiple coats, Prompt L-Pop results in bond strengths that are not statistically different from those of Prime&Bond NT, a total-etch adhesive...
  20. ncbi Bonding strength to two different surfaces of dentin under simulated pulpal pressure
    S Belli
    Department of Operative Dentistry, , School of Dentistry, Campus, Konya, Turkey
    J Adhes Dent 3:145-52. 2001
    ....
  21. ncbi Bond strength of self-etching primers to enamel and dentin of primary teeth
    F G Agostini
    Department of Pediatric Dentistry, University of Texas Health Science Center at Houston Dental Branch, USA
    Pediatr Dent 23:481-6. 2001
    ..5 MPa). CONCLUSIONS: The results of this in vitro study show that the four adhesive systems tested bonded effectively to enamel of primary teeth, but only CSE achieved adequate bond strengths to dentin of primary teeth...
  22. ncbi The extent to which resin can infiltrate dentin by acetone-based adhesives
    M Hashimoto
    Department of Operative Dentistry and Endodontics, Iwate Medical University, School of Dentistry, Morioka, Japan
    J Dent Res 81:74-8. 2002
    ..Based on those findings, it was suggested that the integrity between the bonding resin and the top of the hybrid layer played a major role in bond strength...
  23. ncbi A comparison of microtensile bond strengths of several dentin bonding systems to primary and permanent dentin
    M F Burrow
    School of Dental Science, The University of Melbourne, 711 Elizabeth Street, Melbourne, Victoria 3000, Australia
    Dent Mater 18:239-45. 2002
    ..The bonded interfaces were also observed using field emission electron microscopy(FE-SEM)...
  24. ncbi Fracture aspects of resin-dentin bonding in non-trimming microtensile test
    K K Chen
    Department of Operative Dentistry, Kyushu Dental College, 2-6-1 Manazuru, Kokurakita, Kitakyushu, 803-8580, Japan
    Dent Mater J 20:315-24. 2001
    ..These results suggest that the non-trimming microtensile test may potentially provide more realistic aspects of resin-dentin bonding than the conventional bulk specimen...
  25. ncbi Influence of bonding agent composition on flexural properties of an Ultra-High Molecular Weight Polyethylene Fiber-Reinforced Composite
    A E Ellakwa
    The University of Birmingham, The School of Dentistry, Biomaterials Unit, UK
    Oper Dent 27:184-91. 2002
    ..Silane pre-treatment of UHMWPE fiber before impregnation with the bonding agent significantly reduced the flexural strength (p<0.05)...
  26. ncbi The in vitro dentin bond strengths of two adhesive systems in class I cavities of human molars
    Toru Nikaido
    Cariology and Operative Dentistry, Department of Restorative Sciences, Tokyo Medical and Dental University, Japan
    J Adhes Dent 4:31-9. 2002
    ..The purpose of this study was to evaluate the in vitro dentin bond strengths of two dentin bonding systems in Class I cavities following fatigue load cycling (FLC) with thermal cycling (TC)...
  27. ncbi Effect of moist bonding on composite/enamel bond strength
    Karlheinz Moll
    Department of Conservative Dentistry, Periodontology and Pedodontics, University of Ulm, Germany
    Am J Dent 15:85-90. 2002
    ..To evaluate the effect of moist bonding on shear bond strength of resin-based composite to enamel using different adhesive systems...
  28. ncbi Effect of irrigation solutions on dentin bonding agents and restorative shear bond strength
    Eric C Sung
    Division of Advanced Prosthodontics, Biomaterials, and Hospital Dentistry, School of Dentistry, University of California at Los Angeles, Los Angeles, 90095 1668, USA
    J Prosthet Dent 87:628-32. 2002
    ..The presence of irrigation solution prior to the application of dentin bonding agents may be one source of contamination and may adversely affect bond strength...
  29. ncbi Micro-tensile bond testing of resin cements to dentin and an indirect resin composite
    Yiu Fai Mak
    Conservative Dentistry, Faculty of Dentistry, University of Hong Kong, Prince Philip Dental Hospital, 34 Hospital Road, SAR, Hong Kong, People s Republic of China
    Dent Mater 18:609-21. 2002
    ....
  30. ncbi Evaluation of microleakage using different bonding agents
    Ricardo Maio Gagliardi
    Department of Dentistry, School of Health Science, University of Brasilia
    Oper Dent 27:582-6. 2002
    ..05) leakage at dentin margins for all adhesive systems when compared to the control. Except for Durafill Bond, no significant difference was found between the self-etching adhesives and one-bottle adhesives...
  31. ncbi Comparison of shear bond strength relative to two testing devices
    Nikole Pecora
    School of Dentistry, University of Michigan, 1011 N University Avenue, Ann Arbor, MI 48109 1078, USA
    J Prosthet Dent 88:511-5. 2002
    ..To realistically compare bond strengths, the testing mechanisms must be the same...
  32. ncbi A comparison of the adhesion of three restorative materials
    Teresa R Tripi
    Department of Conservative Dentistry, University of Catania, Italy
    J Clin Dent 13:234-9. 2002
    ..For this investigation, 45 extracted lower wisdom molars were selected and 45 Class I cavities were prepared by the same operator, and were randomly divided into three groups of 15 samples each...
  33. ncbi The effect of different drying methods for single step adhesive systems on microleakage of tooth colored restorations
    Barry M Owens
    Department of Restorative Dentistry, University of Tennessee, College of Dentistry, 875 Union Avenue, Memphis, TN 38163, USA
    J Contemp Dent Pract 4:1-9. 2003
    ..Significantly greater leakage was also recorded with OptiBond Solo Plus and Prime & Bond 2.1 sponge applicator drying as compared to the same materials, syringe air drying...
  34. ncbi Determination of residual double bonds in resin-dentin interface by Raman spectroscopy
    M Miyazaki
    Department of Operative Dentistry, Nihon University School of Dentistry, 1 8 13, Kanda Surugadai, Chiyoda ku, 101 8310, Tokyo, Japan
    Dent Mater 19:245-51. 2003
    ..The purpose of this study was to investigate a method to analyze the percentage of adhesive resin residual double bonds in the dentin-resin interface using laser Raman spectroscopy...
  35. ncbi Bonding characteristics of self-etching adhesives to intact versus prepared enamel
    Jorge Perdigao
    Division of Operative Dentistry, Department of Restorative Sciences, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Esthet Restor Dent 15:32-41; discussion 42. 2003
    ..This study tested the null hypothesis that the preparation of the enamel surface would not affect the enamel microtensile bond strengths of self-etching adhesive materials...
  36. ncbi Storage effect on the shear bond strength of adhesive systems
    Alysson Noriyuki Kajishima Konno
    Discipline of Dental Materials, Faculty of Dentistry of Piracicaba, UNICAMP, Piracicaba, SP, Brazil
    Braz Dent J 14:42-7. 2003
    ..05). In addition. CLB2V had the highest means at all times tested. SOLO had the lowest mean shear bond strength at 6 months, which was statistically lower than means at 3 months and 1 day (p < 0.05)...
  37. ncbi The effect of air abrasion with two new bonding agents on composite repair
    Nurhan Oztas
    Faculty of Dentistry, Department of Pedodontics, Gazi University, Turkey
    Oper Dent 28:149-54. 2003
    ..The results showed that surface treatment with air abrasion plus Optibond Solo application had the highest shear bond strength...
  38. ncbi Efficacy of a resin coating on bond strengths of resin cement to dentin
    Primali R Jayasooriya
    Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    J Esthet Restor Dent 15:105-13; discussion 113. 2003
    ....
  39. ncbi Influence of the substrate and load application method on the shear bond strength of two adhesive systems
    Paulo Eduardo Capel Cardoso
    Department of Dental Materials, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil
    Oper Dent 28:388-94. 2003
    ..05). SEM examination found that Etch&Prime 3.0 demonstrated narrower tags than Single Bond. Moreover, the peritubular dentin was not adequately decalcified when Etch&Prime 3.0 was used...
  40. ncbi Immediate and 24-hour bond strengths of two dental adhesive systems to three tooth substrates
    Yousef Fouad Talic
    Department of Prosthetic Dental Sciences at King Saud University College of Dentistry, Riyadh, Kingdom of Saudi Arabia
    J Contemp Dent Pract 4:28-39. 2003
    ..Significant differences were found between immediate and 24-hour bond strengths, but there were essentially no differences between substrates or adhesives...
  41. ncbi Influence of different repair procedures on bond strength of adhesive filling materials to etched enamel in vitro
    Christian Hannig
    Department of Operative Dentistry, Preventive Dentistry and Periodontology, University of Gottingen, Gottingen, Germany
    Oper Dent 28:800-7. 2003
    ....
  42. ncbi Tensile bond strengths of resin cements to bovine dentin using resin coating
    Toru Nikaido
    Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, Tokyo 113 8549, Japan
    Am J Dent 16:41A-46A. 2003
    ..To evaluate the effect of a resin coating technique on dentin tensile bond strengths of dual-cured resin cements...
  43. ncbi Effect of different polymerization methods on composite microleakage
    Simone Deliperi
    Department of Conservative Dentistry, University of Cagliari, Italy
    Am J Dent 16:73A-76A. 2003
    ..To evaluate the microleakage of a condensable resin composite using a microhybrid flowable composite as a liner, cured with four different methods of polymerization...
  44. ncbi Microtensile bond strength of several adhesive systems to different dentin depths
    Manuel Toledano
    Department of Dental Materials, School of Dentistry, University of Granada, Spain
    Am J Dent 16:292-8. 2003
    ..To determine the bond strength of five adhesives systems to either superficial or deep dentin...
  45. ncbi Effect of 2% chlorhexidine on microtensile bond strength of composite to dentin
    Fabrício Luscino Alves de Castro
    Department of Restorative Dentistry, Araraquara School of Dentistry, UNESP Araraquara, Sao Paulo, Brazil
    J Adhes Dent 5:129-38. 2003
    ..To evaluate the effect of 2% chlorhexidine on the microtensile bond strength of composite resin to dentin treated with three dentin bonding systems...
  46. ncbi Experimental comparison of cavity sealing ability of five dental adhesive systems after thermocycling
    Liem Cao
    Department of Conservative Dentistry, University of Liege, Belgium
    J Adhes Dent 5:139-44. 2003
    ....
  47. ncbi Effect of EDTA conditioning on bond strength to bovine dentin promoted by four current adhesives
    Yasuhiro Torii
    Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School for Medicine and Dentistry, Japan
    Am J Dent 16:395-400. 2003
    ..To investigate the effect of disodium dihydrogen ethylenediamine tetraacetate dihydrate (EDTA) conditioning prior to the application of adhesive systems on the bond strength of resin composite to dentin...
  48. ncbi The effect of variation in etching times on dentin bonding
    Amer Abu-Hanna
    University of Florida College of Dentistry, Department of Operative Dentistry, Gainesville, USA
    Gen Dent 52:28-33. 2004
    ..Reducing etching time reduces the depth of the demineralized zone and may be effective for achieving complete penetration and for sealing the dentin surface...
  49. ncbi In vivo degradation of resin-dentin bonds produced by a self-etch vs. a total-etch adhesive system
    K Koshiro
    Department of Oral Health Science, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan
    Eur J Oral Sci 112:368-75. 2004
    ..It is concluded that even though the bond strengths of both adhesive systems declined over time, the bonding interface using self-etching primers was relatively stable over time compared to the wet bonding system...
  50. ncbi Evaluation of etching time on dentin bond strength using single bottle bonding systems
    Amer Abu-Hanna
    Department of Operative Dentistry, College of Dentistry, University of Florida, Health Science Center, Gainsville, Florida, 32610 0415, USA
    J Adhes Dent 6:105-10. 2004
    ..The current study evaluates whether reducing the etching time to 5 s from the recommended 15 s or increasing it to 30 s has an effect on dentin bonding...
  51. ncbi Effects of flowable resin on bond strength and gap formation in Class I restorations
    Patricia A Miguez
    Curriculum in Oral Biology, University of North Carolina, 101 Dental Research Center, CB 7455, Chapel Hill 7455, USA
    Dent Mater 20:839-45. 2004
    ..This study measured resin/dentin bond strengths and evaluated gap formation at the pulpal floor of occlusal composite restorations using a flowable resin as a liner with either bulk or incremental placement of the restorative composite...
  52. ncbi In vitro influence of Carisolv on shear bond strength of dentin bonding agents
    Maria Carolina Guilherme Erhardt
    FAPESP, Brazil
    Quintessence Int 35:801-7. 2004
    ..The aim of this study was to evaluate the influence of Carisolv on the shear bond strength (SBS) of hydrophilic adhesive systems in dentin...
  53. ncbi Resin-infiltrated-dentine--a FE-ESEM microscopy investigation
    J D Eick
    School of Dentistry, University of Missouri, Kansas City, USA
    SADJ 59:317, 319, 321-2. 2004
    ..No polymerised resin or hybrid layer was observed for Prompt L-Pop. The FE-ESEM permitted observation of specimens at near in-vivo wet conditions...
  54. ncbi Influence of specimen size and regional variation on long-term resin-dentin bond strength
    Alessandro D Loguercio
    School of Dentistry, University of Oeste de Santa Catarina, Joacaba, SC, Brazil
    Dent Mater 21:224-31. 2005
    ..Verify whether the dimension of a bonded specimen stored prior microtensile testing and its regional variation may affect the resin-dentin bond strength (BS) over time...
  55. ncbi Mechanical stability of resin-dentin bond components
    Marcela Rocha de Oliveira Carrilho
    Department of Restorative Dentistry, Dental Materials, Piracicaba School of Dentistry, University of Campinas, Piracicaba, SP, Brazil
    Dent Mater 21:232-41. 2005
    ..To evaluate the effects of long-term storage on the mechanical properties of the components of resin-dentin bonds, that is, resin composite, adhesive system, demineralized and mineralized dentin...
  56. ncbi Dentin bond strength of self-etching primers/adhesives
    Luis Guilherme Sensi
    Department of Operative Dentistry, Universidade Federal de Santa Catarina, Florianopolis, Santa Catarina, Brazil
    Oper Dent 30:63-8. 2005
    ..OP resulted in the highest mean dentin SBS, while the other materials tested in this study (SE and ADH) presented similar dentin SBS to a total-etch one-bottle bonding system (SB)...
  57. ncbi Influence of Carisolv on resin adhesion for two different adhesive systems to sound human primary dentin and young permanent dentin
    Y Hosoya
    Department of Developmental and Reconstructive Medicine, Graduate School of Biomedical Sciences, Nagasaki University, 1 7 1, Sakamoto, Nagasaki, 852 8588 Japan
    J Dent 33:283-91. 2005
    ..This study evaluated the influence of Carisolv (Medi Team) for resin adhesion to sound human primary and young permanent dentin...
  58. ncbi Effect of handpiece maintenance method on bond strength
    Howard W Roberts
    Dental Graduate Biomaterials, Marquette University, Milwaukee WI, USA
    Oper Dent 30:528-32. 2005
    ..Results indicated that within each of the bonding agents, there were no significant differences in bond strength between the control group and the treatment groups regardless of the type of handpiece or use of routine lubrication...
  59. ncbi Effect of an antibacterial adhesive on the bond strength of three different luting resin composites
    Ebru Cal
    Department of Prosthodontics, School of Dentistry, Ege University, 35100 Bornova Izmir, Turkey
    J Dent 34:372-80. 2006
    ..0) to dentin was investigated...
  60. ncbi Does hybridization of intraradicular dentin really improve fiber post retention in endodontically treated teeth?
    Chiara Pirani
    Endodontic Unit, Department of Dental Sciences, Alma Mater Studiorum, University of Bologna, Via San Vitale 59, Bologna, Italy
    J Endod 31:891-4. 2005
    ..The clinical success associated with bonded fiber posts is probably due predominantly to frictional retention...
  61. ncbi Differential effect of in vitro degradation on resin-dentin bonds produced by self-etch versus total-etch adhesives
    Manuel Toledano
    Department of Dental Materials, School of Dentistry, University of Granada Spain, Granada, Spain
    J Biomed Mater Res A 77:128-35. 2006
    ..To evaluate the effect of an in vitro challenge (NaOCl immersion) on microtensile bond strength (MTBS) of five adhesive systems to dentin...
  62. ncbi Effect of cyclic loading on the microtensile bond strengths of total-etch and self-etch adhesives
    Manuel Toledano
    Faculty of Dentistry, University of Granada, Granada, Spain
    Oper Dent 31:25-32. 2006
    ..To evaluate the effect of mechanical loading on the microtensile bond strength (MTBS) of five adhesive systems to dentin...
  63. ncbi Bond strength of total-etch and self-etch dentin adhesive systems on peripheral and central dentinal tissue: a microtensile bond strength test
    C Yesilyurt
    Department of Restorative Dentistry, Faculty of Dentistry, Karadeniz Technical University, Trabzon, Turkey
    J Contemp Dent Pract 7:26-36. 2006
    ..In addition the interface between the adhesive resins and dentin was examined using scanning electron microscopy (SEM)...
  64. ncbi Fatigue resistance of the bond of a glass-infiltrated alumina ceramic to human dentin
    Paolo Baldissara
    Department of Oral Science, University of Bologna, Italy
    J Adhes Dent 8:97-104. 2006
    ..To evaluate the fatigue resistance of the bond between dentin and glass-infiltrated alumina ceramic, using different luting protocols...
  65. ncbi The effects of cavity size and incremental technique on micro-tensile bond strength of resin composite in Class I cavities
    Zhengdi He
    Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, 1 5 45, Yushima, Tokyo 113 8549, Japan
    Dent Mater 23:533-8. 2007
    ..The purpose of this study was to investigate if incremental-filling technique and cavity size would affect the bond strength of resin composite...
  66. ncbi Influence of light-activated and auto- and dual-polymerizing adhesive systems on bond strength of indirect composite resin to dentin
    Maria Jose Lorena de Menezes
    Department of Restorative Dentistry, Piracicaba School of Dentistry, State University of Campinas, SP, Brazil
    J Prosthet Dent 96:115-21. 2006
    ..An inadequate choice may compromise the success of indirect restorations...
  67. ncbi Influence of adhesive systems on interfacial dentin gap formation in vitro
    Alessandro Dourado Loguercio
    Universidade do Oeste de Santa Catarina, Joacaba, Brazil
    Oper Dent 31:431-41. 2006
    ....
  68. ncbi Long-term TEM analysis of the nanoleakage patterns in resin-dentin interfaces produced by different bonding strategies
    Andre F Reis
    Department of Restorative Dentistry, Division of Operative Dentistry, Piracicaba School of Dentistry, University of Campinas, Av Limeira 901, Piracicaba, CEP 13414 903, SP, Brazil
    Dent Mater 23:1164-72. 2007
    ..The aim of this study was to evaluate the ability of etch-and-rinse and self-etching adhesive systems to prevent time- and water-induced nanoleakage in resin-dentin interfaces over a 6-month storage period...
  69. ncbi In vitro bonding performance of all-in-one adhesives. Part I--microtensile bond strengths
    Jorge Perdigao
    Division of Operative Dentistry, Department of Restorative Sciences, University of Minnesota, Minneapolis, MN 55455, USA
    J Adhes Dent 8:367-73. 2006
    ..The objective of this project was to compare the microtensile bond strengths (microTBS) of five "all-in-one" adhesives using two 2-step adhesives as controls...
  70. ncbi Interactions of self-etch adhesives with resin composites
    Rie Kurokawa
    Department of Oral Biological Science, Division of Orthodontics, Niigata University, Japan
    J Dent 35:923-9. 2007
    ....
  71. doi Resistance of ten contemporary adhesives to resin-dentine bond degradation
    Raquel Osorio
    Department of Dental Materials, Campus de Cartuja s n, School of Dentistry, University of Granada, Granada, Spain
    J Dent 36:163-9. 2008
    ..To evaluate resin-dentine bond degradation after 1 year of water storage...
  72. ncbi Surface conditioning of a composite used for inlay/onlay restorations: effect on muTBS to resin cement
    Luiz Felipe Valandro
    Department of Restorative Dentistry, School of Dentistry, Federal University of Santa Maria, Brazil
    J Adhes Dent 9:495-8. 2007
    ..To assess the effect of the composite surface conditioning on the microtensile bond strength of a resin cement to a composite used for inlay/onlay restorations...
  73. doi Effect of chlorhexidine application on microtensile bond strength to dentin
    Carlos Jose Soares
    Operative Dentistry and Dental Materials Department Dental School, Federal University of Uberlandia, Minas Gerais, Brazil
    Oper Dent 33:183-8. 2008
    ..52; 2: 21.62+/-2.5; 1: 21.28+/-3.17; 3: 19.62+/-2.05; 4: 19.55+/-2.34. The use of chlorhexidine at concentrations of 0.12% and 2% before, after or associated with acid etching did not significantly affect the microTBS values to dentin...
  74. ncbi Effect of a papain-based gel for chemomechanical caries removal on dentin shear bond strength
    Michelle Cristina Lopes
    Araras Dental School, Herminio Ometto University Center UNIARARAS, Araras, Sao Paulo, Brazil
    J Dent Child (Chic) 74:93-7. 2007
    ..The aim of this study was to assess the shear bond strength of an adhesive restorative system on sound and demineralized dentin after the use of a papain-based agent...
  75. doi OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines
    W Zhang
    University of Edinburgh, Osteoarticular Research Group, The Queen s Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, United Kingdom
    Osteoarthritis Cartilage 16:137-62. 2008
    ....
  76. ncbi Effect of screening for cancer in the Nordic countries on deaths, cost and quality of life up to the year 2017
    L Hristova
    Finnish Cancer Registry, University of Tampere School of Public Health
    Acta Oncol 36:1-60. 1997
    ..The total cost of the three screening programmes was estimated at $4400 per life years gained in the year 2010.(ABSTRACT TRUNCATED)..
  77. ncbi A systematic overview of chemotherapy effects in acute myeloid leukaemia
    E Kimby
    Department of Haematology, University Hospital, Huddinge, Sweden
    Acta Oncol 40:231-52. 2001
    ..Patients with relapsed AML can only infrequently achieve long-term remissions with chemotherapy in conventional doses. trolled data indicate that allogeneic transplantation can be a curative treatment for these patients a..
  78. ncbi Testing strategies in mutagenicity and genetic toxicology: an appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes
    D J Kirkland
    Covance Laboratories Limited, Otley Road, Harrogate HG3 1PY, UK
    Mutat Res 588:88-105. 2005
    ..The generation of such data is encouraged...
  79. ncbi [Not Available]
    A Carlino
    Istituto Universitario Europeo, Firenze
    Physis Riv Int Stor Sci 31:731-69. 1994
    ..Through fugitive sheets, anatomical knowledge partially lost its strictly scientific connotations and was adapted to a multiplicity of often quite unexpected uses...
  80. doi Waterborne adenovirus
    Kristina D Mena
    University of Texas, Houston School of Public Health, Houston, Texas, USA
    Rev Environ Contam Toxicol 198:133-67. 2009
    ..2). More data are needed regarding effectiveness of water treatment against adenovirus and the human-virus dose-response relationship to fully understand the role of adenovirus as a waterborne public health threat...
  81. ncbi Using a set of strategic indicator systems as a decision-making support implement for establishing a recycling-oriented society. A Taiwanese case study
    I Cheng Chang
    Department of Environmental Engineering, Lan Yang Institute of Technology, No 79, Fushing Rd, Toucheng, Ilan County, Taiwan 261
    Environ Sci Pollut Res Int 12:96-108. 2005
    ..ROSAIS, on the one hand, can act as a compass for understanding resource using efficiency and recycling status during city development and, on the other hand, can serve as an implement supporting decision-making for ROS construction...
  82. ncbi Morphogenic and tumorigenic potentials of the mammary growth hormone/growth hormone receptor system
    Evert Van Garderen
    Department of Pathology, Utrecht University, Utrecht, The Netherlands
    Mol Cell Endocrinol 197:153-65. 2002
    ..Consistent with the findings on the canine GHR, different GHR transcripts in human mammary cancer cells and prostate cancer cells were detected encoding the full-length plasma membrane GHR and putative GHBPs...
  83. ncbi A systematic review of in vivo retrograde obturation materials
    R Niederman
    The Forsyth Institute, 140 The Fenway, Boston, MA 02115, USA
    Int Endod J 36:577-85. 2003
    ..resection) and retrograde (root-end) obturation (filling), which retrograde obturation (root-end filling) material(s) is/are the most effective, as determined by reduction in periapical radiolucency and elimination of signs and symptoms?..
  84. ncbi Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV-infection
    M Briel
    University Hospital Basel, Basel Institute for Clinical Epidemiology, Internal Medicine, Hebelstrasse 10, Basel, Switzerland 4031
    Cochrane Database Syst Rev . 2006
    ..It was suggested that in these patients corticosteroids adjunctive to standard treatment for PCP could prevent the need for mechanical ventilation and decrease mortality...
  85. ncbi [The solution of stress urinary incontinence in women by the TVT-S surgical method--correlation between the curative effect of this method and changes in ultrasound findings]
    A Martan
    Gynekologicko porodnická klinika VFN a 1 LF UK, Praha
    Ceska Gynekol 73:271-7. 2008
    ..Another aim of our study was to determine indications for particular position of the tape (the "hammock" or "U" position) based on ultrasonographic findings of the urethra and the tape position following TVT-S...
  86. pmc Permissive stimulation of Ca(2+)-induced phospholipase A2 by an adenosine receptor agonist in a pertussis toxin-sensitive manner in FRTL-5 thyroid cells: a new 'cross-talk' mechanism in Ca2+ signalling
    S Shimegi
    Department of Physical Biochemistry, Gunma University, Maebashi, Japan
    Biochem J 299:845-51. 1994
    ....
  87. ncbi Efficacy of new, concise schedule for melarsoprol in treatment of sleeping sickness caused by Trypanosoma brucei gambiense: a randomised trial
    C Burri
    Swiss Tropical Institute, Basel
    Lancet 355:1419-25. 2000
    ..Despite these problems, melarsoprol is likely to remain the drug of choice for the next decade. We therefore did a randomised trial comparing the standard treatment schedule with a new, concise regimen...
  88. ncbi Narrative verdicts and their impact on mortality statistics in England and Wales
    Chris Hill
    Office for National Statistics
    Health Stat Q 49:81-100. 2011
    ..This will ensure that mortality statistics are maintained to the highest standards.List of Tables, 83...
  89. doi Practical synthesis of fluorine-containing α- and β-amino acids: recipes from Kiev, Ukraine
    Valery P Kukhar
    Department of Chemistry and Biochemistry, The University of Oklahoma, 620 Parrington Oval, Room 208, Norman, OK 73019 3051, USA
    Future Med Chem 1:793-819. 2009
    ..We hope this review of synthetic methods will highlight and bring attention to particular types of fluorinated amino acids and related compounds readily available on a laboratory scale using methods developed by our group...
  90. ncbi [The hyoid bone and vertical dimension]
    A Doual
    Faculté d Odontologie, Lille
    Orthod Fr 74:333-63. 2003
    ..Recent studies now also show that the contribution the hyoid bone makes to respiratory equilibrium is far more important than its small size would suggest...
  91. pmc Effects of smoking cessation, acute re-exposure and nicotine replacement in smokers on AIR inhaled insulin pharmacokinetics and glucodynamics
    Alan X Pan
    Lilly NUS Centre for Clinical Pharmacology Pte Ltd, Singapore
    Br J Clin Pharmacol 65:480-7. 2008
    ....
  92. ncbi Oxidative stress in the molecular mechanism of pathogenesis at different diseased states of organism in clinics and experiment
    Konstantin G Karageuzyan
    Institute of Molecular Biology, National Academy of Sciences of the Republic of Armenia, 7, Hasratyan Str, Yerevan 375014, Republic of Armenia
    Curr Drug Targets Inflamm Allergy 4:85-98. 2005
    ..These data serve a sound affirmation for protectory function of STS, detailed revelation of molecular properties of pathogenesis of the studied intoxication to which a part of our clinical and experimental studies at present is devoted...
  93. ncbi T lymphocyte-deficient mice lose trabecular bone mass with ovariectomy
    Sun Kyeong Lee
    Division of Endocrinology, Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut 06030 5456, USA
    J Bone Miner Res 21:1704-12. 2006
    ..In TLD mice, OVX caused trabecular bone loss equivalent to that of WT. In contrast, cortical bone loss with OVX was variable. We conclude that T lymphocytes do not influence OVX-induced trabecular bone loss...
  94. ncbi The role of impact forces and foot pronation: a new paradigm
    B M Nigg
    Human Performance Laboratory, Faculty of Kinesiology, The University of Calgary, Alberta, Canada
    Clin J Sport Med 11:2-9. 2001
    ..This article discusses the possible association between impact forces and foot pronation and the development of running-related injuries, and proposes a new paradigm for impact forces and foot pronation...
  95. ncbi Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) as an adaptogen: a closer look
    M Davydov
    Department of Biochemistry and Cell Biology, State University of New York at Stony Brook, 11794 5215, USA
    J Ethnopharmacol 72:345-93. 2000
    ..abstract truncated)..
  96. doi Critical review of the World Health Organization's (WHO) 2007 report on 'evidence of the long-term effects of breastfeeding: systematic reviews and meta-analysis' with respect to obesity
    M B Cope
    Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL, USA
    Obes Rev 9:594-605. 2008
    ....
  97. ncbi Systematics of the lizard family pygopodidae with implications for the diversification of Australian temperate biotas
    W Bryan Jennings
    Section of Integrative Biology, University of Texas, Austin, Texas 78712, USA
    Syst Biol 52:757-80. 2003
    ..These sympatric sister species seem to be younger than allopatric or parapatric sister-species pairs, which is not consistent with previous beliefs...
  98. doi Proarrhythmic risk with antipsychotic and antidepressant drugs: implications in the elderly
    W Victor R Vieweg
    Department of Psychiatry, Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond, Virginia 23238 5414, USA
    Drugs Aging 26:997-1012. 2009
    ..Finally, nothing in our recommendations replaces meticulous attention to US FDA guidelines in the package insert of each drug...
  99. ncbi Development of a head and neck companion module for the quality of life-radiation therapy instrument (QOL-RTI)
    A Trotti
    Division of Radiation Oncology, and the Biostatistics Core, University of South Florida, James A Haley VA Medical Center, Tampa, USA
    Int J Radiat Oncol Biol Phys 42:257-61. 1998
    ..The goal was to create a more complete, yet concise, head and neck site-specific module geared toward patients receiving radiation therapy for head and neck cancer...
  100. doi Video-assisted thoracoscopic surgery or transsternal thymectomy in the treatment of myasthenia gravis?
    Imran Zahid
    Imperial College London, South Kensington Campus, London SW7 2AZ, UK
    Interact Cardiovasc Thorac Surg 12:40-6. 2011
    ..177±92 min, P<0.05), its improved cosmesis, reduced need for postoperative medication and equivalent disease resolution outcomes make it a preferable surgical option to the transsternal approach...
  101. ncbi [Spemann's organizer--it's origin and derivatives (cellular-tissue and molecular-genetic aspects)]
    Iu N Gorodilov
    Biological Research Institute, St Petersburg State University
    Tsitologiia 43:182-203. 2001
    ..This inference is supported by the fact that all the three above structures first originate in vertebrates only...

Research Grants94

  1. SPEAKER TRAVEL AND SCIENTIFIC SESSION SUPPORT FOR THE TERATOLOGY SOCIETY 50TH
    Christina Chambers; Fiscal Year: 2011
    ..Add Optional Project Narrative File Delete Optional Project Narrative File View Optional Project Narrative File !"#! ..
  2. Epigenomic Events in Development of the Locus Coeruleus Noradrenergic Neurons
    Jan Krzysztof Blusztajn; Fiscal Year: 2012
    ..g. galanin, NPY, VIP, substance P) phenotype. A large collection of the relevant EGFP-expressing transgenic mouse lines has been generated and is available at the NIH- supported GENSAT resource. ..
  3. Robert L Nussbaum; Fiscal Year: 2014
    ..Finally, after completing a 10-generation backcross onto C57Bl/6, we will examine the mice for abnormalities in central nervous system by testing motor function, anxiety, learning, memory and by examining the brains neuropathologically. ..
  4. FUNCTIONAL PROPERTIES OF HEMOGLOBINS AND MYOGLOBINS
    John S Olson; Fiscal Year: 2010
    ....
  5. Mechanisms for Cardiovascular Effects of air pollutants: Effect of Age and Sex
    BRITT HOLMEN; Fiscal Year: 2010
    ....
  6. Nicola C Partridge; Fiscal Year: 2016
    ..Moreover, it will define how HDACs contribute to this. In so doing, the data will also provide new perspectives into treatment of disorders of calcium metabolism, cancer-associated bone disease and other bone disorders. ..
  7. Evaluation of novel FoxM1 inhibitors against liver cancer
    Andrei L Gartel; Fiscal Year: 2012
    ..Completion of our proposal will enable us to determine if thiazole antibiotics are suitable for further clinical development. ..
  8. Novel Small Molecule Therapeutics to Treat Obesity
    SUSAN MEDGHALCHI; Fiscal Year: 2010
    ..FASgen has developed the first pharmacological inhibitors of GPAT that are effective in reducing weight in diet-induced obese mice. This grant will enable FASgen to rapidly move these compounds toward drug development. ..
  9. Beverly H Koller; Fiscal Year: 2014
    ....
  10. Kelly A Birdwell; Fiscal Year: 2015
    ..This will allow me to compete effectively for future NIH support and propel me to an independent career in patient-oriented research. ..
  11. TSQ Vantage Bundle with Acquity UltraPerformance LC
    Nicolaas E Deutz; Fiscal Year: 2010
    ....
  12. Effect of Baclofen on Alcohol Cue-Elicited Urges to Drink and Smoke
    GEORGE ANTHONY KENNA; Fiscal Year: 2011
    ..This gain in knowledge may lead to more effective pharmacological treatments for alcoholic smokers. ..
  13. ISABELLE CATHERINA ROUX; Fiscal Year: 2015
    ..The extensive characterization of synapse formation and maintenance at the neuromuscular junction can then aid our understanding on how these processes might work in the inner ear. ..
  14. Web-Based Program to Improve Antidepressant Medication Adherence
    Rebekah K Hersch; Fiscal Year: 2011
    ..Such a program, if effective, will greatly expand access to an effective medication adherence program, thereby improving the clinical outcomes of people with depression and reducing the likelihood of depression relapse. ..
  15. Virtual Screening Development to Complement Experimental Screening for PPAR Modul
    Stephanie N Lewis; Fiscal Year: 2012
    ....
  16. ERIC DOUGLAS AUSTIN; Fiscal Year: 2014
    ..This will allow me to compete effectively for future NIH support and propel me to an independent career in patient-oriented research. ..
  17. Adil Bashir; Fiscal Year: 2014
    ..The proposed project aims to develop new methodology to measure and understand energy disorders in cardiovascular disease and the techniques developed will be critically useful to advance basic research and medical care. ..
  18. 2010 and 2012 Membrane Transport Proteins
    Robert H Edwards; Fiscal Year: 2012
    ..The conferences will conclude with a plenary lecture that integrates work on the molecular and cellular analysis of membrane transport proteins with physiology and disease. ..
  19. Transgenic Study of ALS-Linked CCS Mutations
    Han Xiang Deng; Fiscal Year: 2011
    ..However, it remains to be determined if these CCS mutations are causative of ALS. This project is designed to test if CCS is a novel ALS-causing gene, using a transgenic approach. ..
  20. Dialysis Infection and Vitamin D in New England: The DIVINE Study
    Ravi Thadhani; Fiscal Year: 2012
    ..These data will also provide an important foundation for designing clinical trials rigorously assessing the effect of nutritional vitamin D on infectious and other complications in ESRD. ..
  21. Stress as a determinant of smoking among sub-populations of Blacks in the U.S.
    Adebola O Odunlami; Fiscal Year: 2011
    ..Furthermore, as a Black, female, immigrant, I have been exposed to differential treatment in various U.S. institutions, including education and healthcare, which have made me aware of my social status as a "triple minority". ..
  22. Searching for Novel Analgesic and Anti-inflammatory Agents
    Guigen Li; Fiscal Year: 2010
    ..The present NIH-R15 grant will greatly benefit PI's undergraduate and graduate education and help the PI to attract more students into sciences. ..
  23. Yilun Liu; Fiscal Year: 2015
    ..Crucially, our detailed knowledge on the DNA replication factors will aid in the discovery of new cancer therapy treatments, since inhibiting DNA replication factors effectively prevents cell proliferation. ..
  24. Perinatal Exposure to Environmental DDT and Risk of Metabolic Syndrome
    Michele La Merrill; Fiscal Year: 2012
    ..The ultimate goal of this work is to understand the possible contribution of DDT to metabolic syndrome and to use this information to design strategies for the prevention of metabolic syndrome. ..
  25. Micro-patterned surfaces for reducing the risk of catheter-associated UTI
    SHRAVANTHI REDDY; Fiscal Year: 2012
    ....
  26. REMIGIO MEDINA OLVEDA; Fiscal Year: 2016
    ....
  27. The role of taste in amino acid appetite
    Ivan E de Araujo; Fiscal Year: 2013
    ..Our work may provide new insights on the exact roles of taste quality and metabolism in sugar overconsumption. ..
  28. Jeffrey R Capadona; Fiscal Year: 2014
    ....
  29. Vaccination with IL-15 DC to Generate Melanoma-specific Protective Memory T Cells
    Anna Karolina Palucka; Fiscal Year: 2013
    ..Current therapies have the potential to improve outcome in a fraction of patients but are associated with considerable toxicity. Vaccination with melanoma antigen-loaded dendritic cells (DCs) could improve outcomes without toxicity. ..
  30. Allergic asthma and chromium exposure
    Steven R Patierno; Fiscal Year: 2010
    ..The findings from the proposed studies will provide the first complete characterization of lung immune responses to inhaled particulate chromates. ..
  31. Developing a Skin Toxicity-Related Quality of Life Scale for Breast Radiotherapy
    Julie B Schnur; Fiscal Year: 2012
    ....
  32. JASON JOSEPH WINNICK; Fiscal Year: 2014
    ....
  33. Yabing Chen; Fiscal Year: 2016
    ..PHS 398/2590 (Rev. 09/04, Reissued 4/2006) Page Continuation Format Page ..
  34. Health-Related Quality of Life in Huntington?s Disease Research and Practice: De
    Noelle E Carlozzi; Fiscal Year: 2010
    ....
  35. Monocyte P311 Expression Level as Predictor of Hypertension in Mice
    Lucia Schuger; Fiscal Year: 2010
    ..Based on preliminary studies, the main goal of this project is to demonstrate that baseline P311 level in blood monocytes represents a useful biomarker to predict the future development and/or severity of hypertension in mice. ..
  36. Xiaoling Wang; Fiscal Year: 2015
    ..We expect to pinpoint specific methylation sites likely to be involved in the pathophysiology of EH. These results might play a key role in the development of new therapeutic targets for early risk stratification and intervention. ..
  37. A Total Synthesis of Gambierol Using an Epoxide-Opening Cascade Approach
    DENISE ANN COLBY; Fiscal Year: 2010
    ..An increased understanding of ion channel structure and function could lead to treatments for arrhythmia and disorders of the central nervous system. ..
  38. Steven J Russell; Fiscal Year: 2015
    ....
  39. Design and synthesis of novel anticonvulsant molecules.
    Rajesh Kumar Mishra; Fiscal Year: 2011
    ..The primary objective of this Proposal is to identify a lead drug candidate with strong anti-convulsant efficacy with an acceptable side-effect profile. ..
  40. Academy Research Conference 2010: New Research on Aging and Hearing Health
    Larry E Humes; Fiscal Year: 2010
    ..This application seeks support for the Academy Research Conference 2010: In with the Old - New Research on Aging and Hearing Health which will engage audiologists and scientists in addressing this important public health area. ..
  41. Michele A La Merrill; Fiscal Year: 2015
    ..abstract_text> ..
  42. Huntington Potter; Fiscal Year: 2015
    ....
  43. Shekher Mohan; Fiscal Year: 2014
    ..I hypothesize that FP receptor activation by PGF2[unreadable] will affect changes in [Ca2+]i and that FP receptor blockade will attenuate those changes. ..
  44. Atlases to Report and Correlate Radiotherapy Dose Distributions with Outcomes
    Andrew Jackson; Fiscal Year: 2013
    ..This should permit the safe delivery of higher biologically effective doses to tumors, resulting in improved local control. ..
  45. Brian Storrie; Fiscal Year: 2014
    ..Moreover, important machinery components in these pathways are involved in such processes as virus infection and aging. Modulation of Golgi associated Rabs may prove to be an important therapeutic approach. ..
  46. Impact of Food Ads &PSAs on Child &Teen Eating &Obesity Across Media Markets
    Leslie B Snyder; Fiscal Year: 2012
    ..The answers are important to public health given the scope of the obesity epidemic among young people, and have the potential to inform future public health interventions and policy recommendations. ..
  47. Role of Irf6 in palatal epithelium
    Youssef A Kousa; Fiscal Year: 2013
    ..Clinically, Aim II provides proof-of principal experiments in mitigating the severity or preventing cleft formation during embryologic development. ..
  48. Adolescent Involvement in Parental Substance Abuse Treatment: Evaluation of EBFT
    Natasha Slesnick; Fiscal Year: 2013
    ..These findings would support the assertion that focus on family dynamics in substance abuse treatment programs is an effective use of resources and an important target of intervention efforts. ..
  49. Correlation of Sendai Virus Mutations with Pathogenicity
    NANCY LUGENE MCQUEEN; Fiscal Year: 2012
    ..Studies on the molecular mechanisms of Sendai virus infections in mice are significant in that they may provide important insights on how to more effectively control similar infections in man. ..
  50. Training in structural biology &glycobiology
    Hui Wu; Fiscal Year: 2012
    ....
  51. Brain Research to Ameliorate Impaired Neurodevelopment-Home-based Intervention
    Waldemar A Carlo; Fiscal Year: 2010
    ....
  52. To demonstrate the feasibility of a home tonometer to monitor IOP without contact
    JIM SON CHOU; Fiscal Year: 2010
    ....
  53. Development of a Practical Non-contact ECG Sensor for Arrhythmia Diagnosis
    Yu M Chi; Fiscal Year: 2012
    ..This SBIR project aims to develop a high-quality non-contact, through-clothing ECG sensor with the potential to change the way cardiac monitoring is performed. ..
  54. Laszlo Prokai; Fiscal Year: 2014
    ....
  55. Multi-source clinical Question Answering system
    Guergana Savova; Fiscal Year: 2010
    ....
  56. Acquisition of Zeiss Cell Observer Spinning Disk Confocal System
    Anastas Popratiloff; Fiscal Year: 2012
    ..The overarching goal of these projects is to improve our understanding of the mechanisms underlying those diseased states and to design novel strategies to eradicate them. ..
  57. Novel Imaging System to Objectively Assess the Natural History of Treated and Unt
    Jessica C Ramella Roman; Fiscal Year: 2011
    ....
  58. Case-only Cancer Clustering for Mobile Populations
    Geoffrey M Jacquez; Fiscal Year: 2010
    ..To our knowledge the techniques and software from this project will be the first to address all of these factors within a single, comprehensive framework. ..
  59. GENETIC AND MOLECULAR STUDIES OF NEUROGENESIS
    Chris Q Doe; Fiscal Year: 2012
    ..Thus, the proposed research is relevant to NIH's mission to reduce the burden to society arising from prevalent environmental and genetic brain disorders. ..
  60. Plant-Derived hepatitis B Vaccine from Biomanufacturing System to Clinical Trial
    Robert Britt; Fiscal Year: 2009
    ....
  61. Autophagy: A critical factor in RPE aging and AMD
    MICHAEL EDWIN BOULTON; Fiscal Year: 2012
    ..We believe that characterization of dysfunction in the autophagic pathway in the RPE of AMD retinas will identify new targets in the treatment of this disease. ..
  62. Coping Long-Term with Attempted Suicide Program - Adolescents
    Shirley Yen; Fiscal Year: 2013
    ..The goal of this treatment development grant is to develop an adjunctive intervention for adolescents who have made a suicide attempt. ..
  63. Zachary C Danziger; Fiscal Year: 2014
    ..We will use the model estimates of the optimal stimulation parameters and flowrates to give ourselves the best chance of success for enhancing urethral sensitivity. ..
  64. Argyrios N Theofilopoulos; Fiscal Year: 2014
    ..The insights gained from these studies are likely to provide a better understanding of the mechanisms by which innate sensors and cells promote disease, and reveal novel targets for therapeutic intervention. ..
  65. Paul A Dayton; Fiscal Year: 2014
    ..The project will conclude with publication of Standard Operating Procedures to disseminate the utility of this new technology. ..
  66. High-throughput screen to discover SERCA activators for heart failure therapy
    David D Thomas; Fiscal Year: 2013
    ..g., cancer, diabetes, muscular dystrophy). Even greater impact will ensue if our approach establishes a new biophysical paradigm for fluorescence-based drug discovery. ..
  67. Non-Invasive and Cost Effective Quantification of Positron Emission Tomography
    Arthur Mikhno; Fiscal Year: 2013
    ....
  68. Shirley Yen; Fiscal Year: 2015
    ..Our proposal meets NIMH Strategic Objective #3. This is a novel intervention for a high-risk acute population via a different mechanism (i.e. PA), and conceptually distinct from other empirically examined theoretical approaches. ..
  69. 9th International Myotonic Dystrophy Consortium Meeting
    Richard T Moxley; Fiscal Year: 2013
    ..The afternoon of this final day will begin with highlights from the previous sessions, followed by advocacy group presentations, and a session for questions and answers from patients and family members. ..
  70. Housing trade-offs as they are perceived and as they affect children's well-being
    Sandra J Newman; Fiscal Year: 2013
    ....
  71. Mechanisms of Dinitroaniline Action, Selectivity and Resistance
    Naomi S Morrissette; Fiscal Year: 2010
    ..In summary, we believe that further study of the dinitroanilines will elucidate new aspects of tubulin function and define novel ways to specifically disrupt parasite tubulins. ..
  72. Quantitative Imaging of Signaling Networks
    KLAUS MICHAEL HAHN; Fiscal Year: 2013
    ..Our developments will be driven by investigation of Rho GTPase coordination, a network with many suspected feedback interactions centrally implicated in the regulation of cell migration. ..
  73. PROTEOGLYCAN SYNTHESIS DURING DEVELOPMENT AND AGING
    Arnold Caplan; Fiscal Year: 1999
    ....
  74. Diet and the Calcium Channel TRPV6 in Colon Hyperplasia
    Sara Peleg; Fiscal Year: 2010
    ..By identifying the target genes for the protective actions of calcium we can design drugs that block their expression/activities and reverse damages that develop during life-long exposure of the colon to calcium-deficient diets. ..
  75. Richard D Stevenson; Fiscal Year: 2016
    ..The results of this study will advance the development of rigorous, evidence-based standards for the practice of CIMT, with the potential for large-scale implementation to produce major benefits for children with CP. ..
  76. Johnny Bee Good: Bees as Models to Study the Hijacking of the Reward System
    Gene E Robinson; Fiscal Year: 2013
    ..abstract_text> ..
  77. Herbert S Terrace; Fiscal Year: 2016
    ..Health Relatedness: These experiments are relevant to Schizophrenia, Autism, Alzheimer's disease, and other conditions whose patient populations have deficits in their performance of TI problems. ..
  78. STEREOCONTROLLED SYNTHESIS OF BIOACTIVE ALKALOIDS
    VIRESH RAWAL; Fiscal Year: 2007
    ..These synthetic compounds, including advanced intermediates, will be submitted for biological testing. [unreadable] [unreadable]..
  79. TERMIS-Americas 2013 Opening Conference Symposium
    Robert E Guldberg; Fiscal Year: 2013
    ..The conference will be rigorously publicized to attract women and underrepresented minorities, with particular focus on historically black universities and medical schools, as well as individuals with disabilities. ..
  80. Natural Selection, Host-Pathogen Interactions, and Insect Outbreaks
    Gregory Dwyer; Fiscal Year: 2013
    ..If models that include host or pathogen evolution do a better job of explaining data on outbreaks, the Pi's will conclude that host and pathogen evolution play a role in insect outbreaks in nature. ..
  81. MICHAEL LAWRENCE KENT; Fiscal Year: 2016
    ..Results will be quickly distributed to the zebrafish community through through publications and the ZIRC web based manual on zebrafish. ..
  82. BIOSYNTHESIS OF ARA-A, 2'-DEOXYCOFORMYCIN AND ANALOGUES
    David Baker; Fiscal Year: 1992
    ..3) Elucidate the biosynthesis of a group of related compounds which includes adecypenol, a cyclopentenyl analogue of 2'-dCF; azepinomycin, a 1,4-diazepine; and nucleocidin, a fluorosugar-containing nucleoside...
  83. ALTERNATIVE ROLES FOR PHOSPHOENOLPYRUVATE CARBOXYKINASE
    Paul Ray; Fiscal Year: 1991
    ..Defined roles for PEPCK might help to elucidate the presence or nature of diseases related to carbohydrate or lipid metabolism...
  84. Metabolism and Age-Related Organophosphate Toxicity
    Janice Chambers; Fiscal Year: 2005
    ..These results will indicate the contribution of detoxication to toxicity level, and will allow more accurate predictions of age-related differences in toxicity. ..
  85. Development of a T cell specific multiple sclerosis drug
    Arthur Vandenbark; Fiscal Year: 2005
    ..The proposed studies will address key milestones to establish clinical safety of VG1000 needed for subsequent proof-of-principle trials to evaluate inhibition of MOG-specific T cell responses and clinical efficacy. ..
  86. Mifepristone for Prevention of Breakthrough Bleeding
    John Jain; Fiscal Year: 2004
    ..If Mifepristone is shown to safely decrease the incidence of breakthrough bleeding, more women may continue DMPA and not place themselves at risk of an unintended pregnancy. ..
  87. Insulin signaling in theca cells from polycystic ovaries
    Denis Magoffin; Fiscal Year: 2006
    ..The results of these studies are expected to yield specific molecular targets for novel therapies to treat women with PCOS. ..
  88. NUTRITIONAL PREVENTION OF POLYPS IN THE LARGE BOWEL
    Edward Bresnick; Fiscal Year: 1992
    ..This request is for the final four years of the planned nine-year study...
  89. GENETIC CONTRIBUTIONS TO RISK FACTORS IN LJP
    THOMAS HART; Fiscal Year: 1999
    ..Systematic assessment of these candidate probes could ultimately provide positive risk markers with which to screen genetically susceptible populations at high risk for LJP, permitting early identification, diagnosis, and treatment. ..