technetium tc 99m aggregated albumin

Summary

Summary: A gamma-emitting radionuclide imaging agent used for the diagnosis of diseases in many tissues, particularly in cardiovascular and cerebral circulation.

Top Publications

  1. ncbi Intraoperative laparoscopic fluorescence guidance to the sentinel lymph node in prostate cancer patients: clinical proof of concept of an integrated functional imaging approach using a multimodal tracer
    Henk G van der Poel
    Department of Urology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    Eur Urol 60:826-33. 2011
  2. ncbi Gastrointestinal complications associated with hepatic arterial Yttrium-90 microsphere therapy
    Ravi Murthy
    Division of Diagnostic Imaging, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    J Vasc Interv Radiol 18:553-61; quiz 562. 2007
  3. ncbi SPECT/CT with 99mTc-MAA in radioembolization with 90Y microspheres in patients with hepatocellular cancer
    Monia E Hamami
    Department of Nuclear Medicine, University Hospital Essen, University at Duisburg Essen, Essen, Germany
    J Nucl Med 50:688-92. 2009
  4. ncbi An easy and reproducible semi-automatic method for the evaluation of 99mTc-galactosyl human serum albumin
    M Koizumi
    Department of Nuclear Medicine, Cancer Institute Hospital, Tokyo, Japan
    Ann Nucl Med 11:345-8. 1997
  5. ncbi Receptor measurements via Tc-GSA kinetic modeling are proportional to functional hepatocellular mass
    K Miki
    Department of Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    J Nucl Med 42:733-7. 2001
  6. ncbi Functional mapping of regional liver asialoglycoprotein receptor amount from single blood sample and SPECT
    Noriyuki Shuke
    Department of Radiology, Asahikawa Medical College, Asahikawa, Hokkaido, Japan
    J Nucl Med 44:475-82. 2003
  7. ncbi Nuclear imaging techniques for the assessment of hepatic function in liver surgery and transplantation
    Wilmar de Graaf
    Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
    J Nucl Med 51:742-52. 2010
  8. ncbi Simple scintigraphic parameters with Tc-99m galactosyl human serum albumin for clinical staging of chronic hepatocellular dysfunction
    K Nakajima
    Department of Nuclear Medicine, Kanazawa University Hospital, Takaramachi, Japan
    Ann Nucl Med 13:5-11. 1999
  9. ncbi Radioguided occult lesion localization (ROLL) and excision of breast lesions using technetium-99m-macroaggregate albumin and air injection control
    R H S Machado
    Departamento de Radiologia, Hospital Universitario Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Brazil
    J Exp Clin Cancer Res 26:323-7. 2007
  10. ncbi Protein-losing enteropathy: diagnosis with (99m)Tc-labeled human serum albumin scintigraphy
    N T Chiu
    Department of Nuclear Medicine, National Cheng Kung University Hospital, 138 Sheng Li Rd, Tainan 704, Taiwan
    Radiology 219:86-90. 2001

Research Grants

Detail Information

Publications196 found, 100 shown here

  1. ncbi Intraoperative laparoscopic fluorescence guidance to the sentinel lymph node in prostate cancer patients: clinical proof of concept of an integrated functional imaging approach using a multimodal tracer
    Henk G van der Poel
    Department of Urology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    Eur Urol 60:826-33. 2011
    ..Integration of molecular imaging and in particular intraoperative image guidance is expected to improve the surgical accuracy of laparoscopic lymph node (LN) dissection...
  2. ncbi Gastrointestinal complications associated with hepatic arterial Yttrium-90 microsphere therapy
    Ravi Murthy
    Division of Diagnostic Imaging, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    J Vasc Interv Radiol 18:553-61; quiz 562. 2007
    ..Our aim is to increase the understanding of the role of various imaging and preventative techniques in minimizing this undesired effect...
  3. ncbi SPECT/CT with 99mTc-MAA in radioembolization with 90Y microspheres in patients with hepatocellular cancer
    Monia E Hamami
    Department of Nuclear Medicine, University Hospital Essen, University at Duisburg Essen, Essen, Germany
    J Nucl Med 50:688-92. 2009
    ....
  4. ncbi An easy and reproducible semi-automatic method for the evaluation of 99mTc-galactosyl human serum albumin
    M Koizumi
    Department of Nuclear Medicine, Cancer Institute Hospital, Tokyo, Japan
    Ann Nucl Med 11:345-8. 1997
    ..A newly developed semi-automated method improved data processing time and deviation of indices in 99mTc-GSA studies. This method should substitute for manual ROI determination...
  5. ncbi Receptor measurements via Tc-GSA kinetic modeling are proportional to functional hepatocellular mass
    K Miki
    Department of Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    J Nucl Med 42:733-7. 2001
    ..803; P < 0.0001). CONCLUSION: Tc-GSA measurement of the total receptor amount is proportional to the number of viable hepatocytes and therefore provides a valid assessment of functional liver mass...
  6. ncbi Functional mapping of regional liver asialoglycoprotein receptor amount from single blood sample and SPECT
    Noriyuki Shuke
    Department of Radiology, Asahikawa Medical College, Asahikawa, Hokkaido, Japan
    J Nucl Med 44:475-82. 2003
    ....
  7. ncbi Nuclear imaging techniques for the assessment of hepatic function in liver surgery and transplantation
    Wilmar de Graaf
    Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
    J Nucl Med 51:742-52. 2010
    ..In liver transplantation, these methods are used to assess graft function and biliary complications...
  8. ncbi Simple scintigraphic parameters with Tc-99m galactosyl human serum albumin for clinical staging of chronic hepatocellular dysfunction
    K Nakajima
    Department of Nuclear Medicine, Kanazawa University Hospital, Takaramachi, Japan
    Ann Nucl Med 13:5-11. 1999
    ..In conclusion, the use of the ROI-area normalized nLHL is recommended instead of the conventional LHL15. The indices of LH15 and T-half could be alternatively used as practical parameters for clinical staging in liver function...
  9. ncbi Radioguided occult lesion localization (ROLL) and excision of breast lesions using technetium-99m-macroaggregate albumin and air injection control
    R H S Machado
    Departamento de Radiologia, Hospital Universitario Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Brazil
    J Exp Clin Cancer Res 26:323-7. 2007
    ..Radioguided surgery turned out to be an important tool in the removal of non-palpable breast lesions, as a simple, fast and feasible method that can be implemented in the clinical routine of patients with non-palpable breast lesions...
  10. ncbi Protein-losing enteropathy: diagnosis with (99m)Tc-labeled human serum albumin scintigraphy
    N T Chiu
    Department of Nuclear Medicine, National Cheng Kung University Hospital, 138 Sheng Li Rd, Tainan 704, Taiwan
    Radiology 219:86-90. 2001
    ..To investigate the diagnostic value of technetium 99m-labeled human serum albumin (HSA) scintigraphy in a group of patients suspected of having protein-losing enteropathy (PLE)...
  11. ncbi Planning transarterial radioembolization of colorectal liver metastases with Yttrium 90 microspheres: evaluation of a sequential diagnostic approach using radiologic and nuclear medicine imaging techniques
    Timm Denecke
    Klinik fur Strahlenheilkunde, Bereiche Radiologie und Nuklearmedizin, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Eur Radiol 18:892-902. 2008
    ..Each part of the diagnostic algorithm showed a relevant impact on patient management. The sequential approach appears to be suitable and keeps the number of unnecessary treatments and therapy risks to a minimum...
  12. pmc Lymphatic drainage patterns from the breast
    Susanne H Estourgie
    Departments of Surgery and Nuclear Medicine, The Netherlands Cancer Institute, Amsterdam, The Netherlands
    Ann Surg 239:232-7. 2004
    ..The aim of this study was to describe the lymphatic drainage patterns from the 5 "quadrants" of the breast...
  13. ncbi Should the hunt for internal mammary chain sentinel nodes begin? An evaluation of 150 breast cancer patients
    Susanne H Estourgie
    Department of Surgery, The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    Ann Surg Oncol 10:935-41. 2003
    ..The aim of this study was to determine the visualization rate, identification rate, and clinical implications of biopsy of sentinel nodes in the internal mammary chain (IMC) in patients with breast cancer...
  14. ncbi Significance of oral administration of sodium perchlorate in planning liver-directed radioembolization
    Amir Sabet
    Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany
    J Nucl Med 52:1063-7. 2011
    ..Our aim was to evaluate whether oral administration of sodium perchlorate (NaClO(4)) before (99m)Tc-MAA scanning will improve its accuracy by blocking free (99m)Tc-pertechnetate gastric uptake...
  15. ncbi Removal of the internal mammary sentinel node in breast cancer
    Anna Domènech-Vilardell
    Department of Nuclear Medicine, University Hospital of Bellvitge IDIBELL, Barcelona, Spain
    Nucl Med Commun 30:962-70. 2009
    ....
  16. ncbi Gated myocardial perfusion tomography versus gated blood pool tomography for the calculation of left ventricular volumes and ejection fraction
    Christian Vanhove
    Division of Nuclear Medicine, University Hospital, Free University of Brussels AZ VUB, 101 Laarbeeklaan, 1090 Brussels, Belgium
    Eur J Nucl Med Mol Imaging 29:735-41. 2002
    ..In conclusion, LV volumes and EF computed on gMPT correlated well with those measured on gBPT. Discrepancies were observed for large volumes presumably because of inaccuracies of gMPT in patients with severe perfusion defects...
  17. ncbi Significance of lymphoscintigraphic mapping with Tc-99m human serum albumin and tin colloid in sentinel lymph node biopsy in breast cancer
    R Kim
    Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734 8553, Japan
    Int J Oncol 19:991-6. 2001
    ..The pattern and direction of the lymphatic drain to the SLN in scintigraphy need to be considered for the elimination of axillary lymph node dissection in node-negative patients with breast cancer...
  18. ncbi The significance of 99mTc-MAA SPECT/CT liver perfusion imaging in treatment planning for 90Y-microsphere selective internal radiation treatment
    Hojjat Ahmadzadehfar
    Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany
    J Nucl Med 51:1206-12. 2010
    ....
  19. ncbi A portable gamma-camera for intraoperative detection of sentinel nodes in the head and neck region
    Lenka Vermeeren
    Department of Nuclear Medicine, Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    J Nucl Med 51:700-3. 2010
    ..We introduced and evaluated a portable gamma-camera for intraoperative visualization of sentinel nodes in the head and neck region...
  20. ncbi Lymphoscintigraphy using technetium-99m HSA-DTPA with SPECT/CT in chylothorax after childbirth
    Mitsuhiro Momose
    Department of Radiology, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto, 390 8621, Japan
    Radiat Med 26:508-11. 2008
    ..Collateral branches of the thoracic duct were found to be ruptured during video-assisted thoracoscopic surgery performed for ligation...
  21. ncbi Randomized clinical trial comparing radioisotope occult lesion localization and wire-guided excision for biopsy of occult breast lesions
    R S Rampaul
    Nottingham Breast Institute, City Hospital, Nottingham NG1 5PB, UK
    Br J Surg 91:1575-7. 2004
    ..Accurate localization of impalpable breast lesions that require biopsy is important. This randomized trial compared radioisotope occult lesion localization (ROLL) with the standard hooked-wire technique...
  22. ncbi Radioguided occult lesion localisation (ROLL) and surgical biopsy in breast cancer. Technical aspects
    C De Cicco
    Nuclear Medicine, Radiology, Senology and Pathology Divisions, European Institute of Oncology, Milan, Italy
    Q J Nucl Med 46:145-51. 2002
    ..In this paper technical aspects of ROLL and results on a large series of patients are reported...
  23. ncbi Radio-guided localization of clinically occult breast lesions (ROLL): a DGH experience
    C R Thind
    St Helens and Knowsley Hospitals, Prescot, UK
    Clin Radiol 60:681-6. 2005
    ..Wire-guided localization (WGL) of clinically occult breast lesions is a well established technique. The aim of this study was to evaluate radio-guided localization (ROLL) within the breast screening service of a district general hospital...
  24. ncbi On-site preparation of technetium-99m labeled human serum albumin for clinical application
    Yuh Feng Wang
    Graduate Institute of Pharmaceutical Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan
    Tohoku J Exp Med 211:379-85. 2007
    ..These data indicate that our preparation of Tc-99m HSA is useful and potentially applicable clinically. In addition, this on-site preparation provides the possibility of labeling a patient's own serum for subsequent clinical application...
  25. ncbi Occult breast lesions: A comparison between radioguided occult lesion localisation (ROLL) vs. wire-guided lumpectomy (WGL)
    R Nadeem
    Department of Surgery, Whiston Hospital, Merseyside, UK
    Breast 14:283-9. 2005
    ..A larger amount of normal breast tissue was excised with WGL, without achieving any better cancer clearance. ROLL provides a feasible alternative to WGL. This quick and simple technique achieves an improved rate of clear margins...
  26. ncbi Internal mammary lymph drainage and sentinel node biopsy in breast cancer - A study on 1008 patients
    E M Heuts
    Department of Surgery, University Hospital Maastricht, The Netherlands
    Eur J Surg Oncol 35:252-7. 2009
    ..The aim of this study was to determine the likelihood of finding IM lymph node metastases in case of IM hotspots on lymphoscintigraphy and evaluate the relevance of IMSN biopsy as a method to improve staging...
  27. ncbi Nasal mucociliary transport: new evidence for a key role of ciliary beat frequency
    Wilbert M Boek
    Department of Otorhinolaryngology, University Hospital Utrecht, The Netherlands
    Laryngoscope 112:570-3. 2002
    ..Nonetheless, the factors determining mucociliary transport are only partially understood. Ciliary beat frequency is assumed to be one of the main parameters, although the experimental evidence remains inconclusive...
  28. ncbi Radioguided occult lesion localization (ROLL) versus wire-guided lumpectomy for non-palpable breast lesions: a randomized prospective evaluation
    Heriberto Medina-Franco
    Department of Surgery, Section of Surgical Oncology, National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico City, Mexico
    J Surg Oncol 97:108-11. 2008
    ..It is important to optimize the localization technique for non-palpable breast lesions...
  29. ncbi Evaluation of nasal mucociliary clearance function in allergic rhinitis patients with technetium 99m-labeled macroaggregated albumin rhinoscintigraphy
    Shung Shung Sun
    Department of Nuclear Medicine, China Medical College Hospital, Taichung, Taiwan
    Ann Otol Rhinol Laryngol 111:77-9. 2002
    ..We suggest that Tc-99m MAA rhinoscintigraphy may be a useful noninvasive tool to evaluate the nasal mucociliary clearance function in allergic rhinitis patients...
  30. ncbi 89Zr-nanocolloidal albumin-based PET/CT lymphoscintigraphy for sentinel node detection in head and neck cancer: preclinical results
    Derrek A Heuveling
    Department of Otolaryngology Head and Neck Surgery, VU University Medical Center, Amsterdam, The Netherlands
    J Nucl Med 52:1580-4. 2011
    ..This study describes the development and evaluation of a nanocolloidal albumin-based tracer specifically dedicated for high-resolution PET detection...
  31. ncbi A self-assembled multimodal complex for combined pre- and intraoperative imaging of the sentinel lymph node
    Tessa Buckle
    Department of Radiology, The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    Nanotechnology 21:355101. 2010
    ..The multimodal ICG-(99m)Tc-NanoColl complex can be used both for lymphoscintigraphy by preoperative single photon emission computed tomography/computed tomography and for surgical navigation by intraoperative fluorescence imaging...
  32. ncbi Evaluation of the effects of nasal septal deviation and its surgery on nasal mucociliary clearance in both nasal cavities
    Bulent Ulusoy
    Department of Otorhinolaryngology Head and Neck Surgery, Ozel Konya Hospital, Konya, Turkey
    Am J Rhinol 21:180-3. 2007
    ..In this study the effects of nasal septal deviation (NSD) and its surgery on nasal mucociliary clearance velocity (NMCV) in both nasal cavities were evaluated...
  33. ncbi Effects of septoplasty and septal deviation on nasal mucociliary clearance
    H Uslu
    Department of Nuclear Medicine, Ataturk University Medical School, Erzurum, Turkey
    Int J Clin Pract 58:1108-11. 2004
    ..Septal deviation affects the mucociliary activity. It is improved by surgery. This study showed that nasal septal deviation reduced the nasal mucociliary activity, and this can easily evaluated with scintigraphy...
  34. ncbi Is prophylactic embolization of the hepatic falciform artery needed before radioembolization in patients with 99mTc-MAA accumulation in the anterior abdominal wall?
    Hojjat Ahmadzadehfar
    Department of Nuclear Medicine, University Hospital Bonn, Sigmund Freud Str 25, 53127 Bonn, Germany
    Eur J Nucl Med Mol Imaging 38:1477-84. 2011
    ..The aim of this retrospective study was to evaluate the incidence and consequences of (99m)Tc-MAA accumulation in the anterior abdominal wall, indicating a patent HFA, in patients undergoing radioembolization of liver tumours...
  35. pmc Cardiovascular response to dobutamine stress predicts outcome in severe sepsis and septic shock
    Anand Kumar
    Section of Critical Care Medicine, Health Sciences Centre St, Boniface Hospital, University of Manitoba, Winnipeg, Manitoba, Canada
    Crit Care 12:R35. 2008
    ..The objective of this study was to assess cardiovascular and metabolic responses to dobutamine as correlates of outcome in patients with severe sepsis or septic shock...
  36. ncbi Bilateral axillary sentinel nodes from breast carcinoma
    Annette Hougaard Chakera
    Department of Plastic Surgery and Burn Unit, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9 DK 2100 Copenhagen, Denmark
    Clin Nucl Med 29:840. 2004
  37. ncbi SPECT-CT for topographic mapping of sentinel lymph nodes prior to gamma probe-guided biopsy in head and neck squamous cell carcinoma
    Arne Wagner
    University Hospital of Cranio Maxillofacial and Oral Surgery, Medical School, University of Vienna, Austria
    J Craniomaxillofac Surg 32:343-9. 2004
    ..Composite functional/anatomical imaging (SPECT-CT) has the potential to enhance topographic orientation and diagnostic sensitivity of sentinel lymph node imaging, but has not yet been applied in the head and neck region...
  38. ncbi Analysis of technical and clinical variables affecting sentinel node localization in patients with breast cancer after a single intradermal injection of 99mTc nanocolloidal albumin
    Domenico Rubello
    Nuclear Medicine Service, S Maria della Misericordia Rovigo Hospital, Rovigo, Italy
    Nucl Med Commun 25:1119-24. 2004
    ....
  39. ncbi Periareolar injections and hot sentinel nodes
    Chun K Kim
    J Nucl Med 45:1597-9; author reply 1599. 2004
  40. ncbi Number of metastatic sentinel nodes as predictor of axillary involvement in patients with breast cancer
    Giorgio Zavagno
    Istituto di Clinica Chirurgica II, University of Padova, Italy
    Breast Cancer Res Treat 86:171-9. 2004
    ..The aim of this study was to investigate factors predictive of NSNs involvement, in order to identify patients with metastatic disease confined to the SN which might avoid ALND...
  41. ncbi The impact of radiopharmaceutical particle size on the visualization and identification of sentinel nodes in breast cancer
    Marjut H Leidenius
    Breast Surgery Unit, Maria Hospital, Helsinki University Hospital, Helsinki, Finland
    Nucl Med Commun 25:233-8. 2004
    ..The aim of this study was to compare the success rate in lymphatic mapping and sentinel node biopsy in breast cancer using two radiopharmaceuticals...
  42. ncbi Lymphatic mapping in early stage breast cancer: comparison between periareolar and subdermal injection
    E Pelosi
    Servizio di Medicina Nucleare Universitario, Ospedale S Giovanni Battista, Torino, Italy
    Nucl Med Commun 24:519-23. 2003
    ..The concordance rate was 92%. In the present study p.a. and s.d. injection of blue dye give similar and comparable results. The periareolar technique is simpler and has several advantages over the subdermal technique...
  43. ncbi Prostate lymphoscintigraphy and radio-guided surgery for sentinel lymph node identification in prostate cancer. Technique and results of the first 350 cases
    Friedhelm Wawroschek
    Department of Urology, Central Hospital Augsburg, Academic Hospital of the Ludwig Maximilian University Munich, Augsburg, Germany
    Urol Int 70:303-10. 2003
    ....
  44. ncbi Effect of increasing the surface sampled by imprint cytology on the intraoperative assessment of axillary sentinel lymph nodes in breast cancer patients
    G Cserni
    Bacs Kiskun County Teaching Hospital, Albert Szent Gyorgyi Medical University, Kecskemet, Hungary
    Am Surg 69:419-23. 2003
    ..The sampling of multiple surfaces is encouraged for a more accurate intraoperative assessment...
  45. ncbi Effect of increased (99m)Tc/(99)Tc ratios on count rates in sentinel node procedures: a randomised study
    G M M Gommans
    Department of Nuclear Medicine, Westfries Gasthuis Hoorn, 1620 AR Hoorn, The Netherlands
    Eur J Nucl Med Mol Imaging 30:1231-5. 2003
    ..SLN procedures performed 2-3 weeks after prior excision biopsy proved reliable as compared to SLN procedures performed simultaneously with lumpectomy...
  46. ncbi Extra-axillary sentinel node biopsy in breast cancer staging--is it necessary?
    M Victorzon
    Department of Surgery, Vasa Central Hospital, Sandviksgatan 2 4, 65130, Vasa, Finland
    Eur J Surg Oncol 29:604-6. 2003
    ..The aim of this study was to assess the value of lymphoscintigraphy in general and extra-axillary lymph node biopsy in particular, based on our experience with sentinel biopsy in 128 consecutive woman undergoing surgery for breast cancer...
  47. ncbi Effect of increased 99mTc/99Tc ratios on count rates in sentinel node procedures: a randomised study
    James R Ballinger
    Eur J Nucl Med Mol Imaging 31:306. 2004
  48. ncbi Subareolar injection may be more accurate than other techniques for sentinel lymph node biopsy in breast cancer
    Giovanni D'Eredita'
    Department of General and Special Surgery, University of Bari, Bari, Italy
    Ann Surg Oncol 10:942-7. 2003
    ....
  49. ncbi Optimised nuclear medicine method for tumour marking and sentinel node detection in occult primary breast lesions
    C De Cicco
    Division of Nuclear Medicine, European Institute of Oncology and University of Milan, Milan, Italy
    Eur J Nucl Med Mol Imaging 31:349-54. 2004
    ....
  50. ncbi Reasons for failure to identify positive sentinel nodes in breast cancer patients with significant nodal involvement
    A Y de Kanter
    Department of Surgery, Erasmus University Medical Centre Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands
    Eur J Surg Oncol 32:498-501. 2006
    ..To analyse causes of failure of sentinel node (SN) procedures in breast cancer patients and assess the role of pre-operative ultrasound examination of the axilla...
  51. ncbi Subareolar injection of technetium-99m nanocolloid yields reliable data on the axillary lymph node tumour status in breast cancer patients with previous manipulations on the primary tumour: a prospective study of 117 patients
    Sofiane Maza
    Clinic for Nuclear Medicine, Charite University Medicine Berlin, Schumannstrasse 20 21, 10117 Berlin, Germany
    Eur J Nucl Med Mol Imaging 31:671-5. 2004
    ..In conclusion, subareolar nanocolloid injection can yield reliable information on the axillary lymph node tumour status in patients with previous manipulations on the primary tumour in the breast...
  52. ncbi Sentinel node biopsy for melanoma: a study of 241 patients
    Annette Hougaard Chakera
    Department of Plastic Surgery and Burn Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen Ø, Denmark
    Melanoma Res 14:521-6. 2004
    ..The complication rate was 6% after SNB and 29% after complete node dissection. In conclusion, SN status is a strong prognostic factor in melanoma patients, and SNB has made the approach to radical lymphadenectomy more rational...
  53. ncbi [Sentinel lymph node biopsy in the breast carcinoma in clinical practice]
    J Gatek
    Chirurgické oddelení nemocnice Atlas a s Zlín, Univerzita Tomáse Bati ve Zlíne
    Rozhl Chir 87:180-5. 2008
    ..In the management of early breast carcinoma, biopsy of sentinel lymph nodes has gradually replaced dissection of Level I and II axillary nodes. The aim of the study is to assess feasability and reliability of the method in our conditions...
  54. ncbi [Sentinel lymph node biopsy in breast cancer. Experience of the Rome Breast Cancer Study Group]
    Lucio Fortunato
    Ospedale S Giovanni Addolorata, Roma
    Chir Ital 58:689-96. 2006
    ..Our multicentric study confirms that this is the preferred axillary staging procedure in women with breast cancer...
  55. ncbi [Subareolar injection for sentinel lymph node biopsy in multiple breast cancer]
    G D'Eredità
    Universita degli Studi di Bari, Dipartimento di Scienze Chirurgiche Generali e Specialistiche
    G Chir 27:436-41. 2006
    ..SA injection technique demonstrates a high sentinel lymph node identification rate and low FN rate; therefore this technique should been recommended to SLNB in patients with MC of the breast...
  56. ncbi Sentinel node biopsy in primary breast cancer: radioactive detection and metastatic disease
    N Wada
    Breast Surgery Division, National Cancer Center Hospital East, 6 5 1, Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
    Eur J Surg Oncol 33:691-5. 2007
    ..To examine the relationship between the intensity of the radioactive counts and the presence of tumor metastasis in sentinel lymph nodes (SLNs) in order to correctly identify the number of SLNs to be removed...
  57. ncbi Breast cancer, Poland's syndrome, and sentinel lymph node involvement
    Jon Uña
    Servicio de Medicina Nuclear, Hospital Universitario Insular de Gran Canaria, Islas Canarias, Spain
    Clin Nucl Med 32:613-5. 2007
    ..Our experience with the present case suggests that the sentinel lymph node biopsy is feasible in patients with Poland's syndrome and breast cancer...
  58. ncbi Sentinel lymph node biopsy in multiple breast cancer using subareolar injection of the tracer
    Giovanni D'Eredita'
    Department of General and Special Surgery, University of Bari, Italy
    Breast 16:316-22. 2007
    ..6% and 93.7%, respectively. SLNB using the SA injection technique may be an alternative to complete axillary dissection in patients with multiple breast cancers and a clinically negative axilla...
  59. ncbi Sentinel lymph node biopsy in the treatment of breast cancer. Experience in 527 cases
    E Procaccini
    Department of Surgery, Second University of Naples, Naples, Italy
    Minerva Chir 62:93-9. 2007
    ..Sentinel lymph node biopsy has proved so reliable in the evaluation of node involvement that axillary node dissection is now generally performed when sentinel node biopsy tests negative...
  60. ncbi Editorial comment on: laparoscopic radioisotope-guided sentinel lymph node dissection in staging of prostate cancer
    Richard Naspro
    Eur Urol 53:132-3. 2008
  61. ncbi Editorial comment on: laparoscopic radioisotope-guided sentinel lymph node dissection in staging of prostate cancer
    Vassilis Poulakis
    Eur Urol 53:133. 2008
  62. ncbi [Sentinel lymph node biopsy for in situ carcinoma of the breast. Experience at the Bács-Kiskun County Hospital and review of the literature]
    Gabor Cserni
    Bács Kiskun Megyei Onkormányzat Kórháza, Patológiai Osztály
    Magy Seb 59:164-72. 2006
    ..Sentinel node biopsy (SNB) is controversial for in situ breast cancers. We reviewed our experience with in situ and microinvasive carcinomas and surveyed the literature...
  63. ncbi [Lymphoscintigraphy and sentinel node biopsy in non-palpable breast cancer]
    A Benítez Segura
    Servicio de Medicina Nuclear, Hospital Universitari de Bellvitge, L Hospitalet de Llobregat, Barcelona, Espana
    Rev Esp Med Nucl 25:250-7. 2006
    ..The aim of the study was to evaluate the efficacy of lymphatic mapping and sentinel node biopsy in non-palpable breast cancer (NPBC) patients in comparison with palpable breast cancer (PBC) patients...
  64. ncbi Factors affecting failed localisation and false-negative rates of sentinel node biopsy in breast cancer--results of the ALMANAC validation phase
    Amit Goyal
    Department of Surgery, Wales College of Medicine, Cardiff University, Cardiff, United Kingdom
    Breast Cancer Res Treat 99:203-8. 2006
    ..A major aim of this prospective multicentre validation study was to quantify detection and false-negative rates of SLNB and evaluate factors influencing them...
  65. ncbi Laparoscopic sentinel node dissection for prostate carcinoma: technical and anatomical observations
    Willem Meinhardt
    Departments of Urology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    BJU Int 102:714-7. 2008
    ..To report experience with sentinel node (SN) lymphadenectomy which allows an assessment of the exact location of radioactive and of tumour-bearing lymph nodes, and evaluate differences in timing of the scintigraphy and surgery...
  66. ncbi Clinical axillary recurrence after sentinel node biopsy in breast cancer: a follow-up study of 220 patients
    A Sanjuan
    Department of Gynecology and Obstetrics, Breast Pathology Unit, Hospital Clinic, University of Barcelona, Spain
    Eur J Nucl Med Mol Imaging 32:932-6. 2005
    ..The aim of this study was to evaluate the frequency of false-negative (FN) sentinel node procedures in patients with breast cancer and the subsequent clinical outcome in such patients...
  67. ncbi Impact of axillary nodal metastases on lymphatic mapping and sentinel lymph node identification rate in patients with early stage breast cancer
    Ettore Pelosi
    S C D U Medicina Nucleare 2, Ospedale S Giovanni Battista, Turin, Italy
    Eur J Nucl Med Mol Imaging 32:937-42. 2005
    ..The aim of this study was to define the impact of the presence of axillary nodal metastases on lymphatic mapping and sentinel lymph node (SLN) identification rate in patients with early breast cancer...
  68. ncbi [Role of sentinel lymph nodes in treatment of head and neck cancer]
    J Manasterski
    Katedra i Klinika Otolaryngologii Akademii Medycznej im Karola Marcinkowskiego w Poznaniu
    Otolaryngol Pol 55:635-9. 2001
    ..Methods of identification of the sentinel lymph nodes are described. Usefulness of the handheld gamma probe to determine the position of sentinel nodes during operative procedure was emphasised...
  69. ncbi Radiation doses to staff involved in sentinel node operations for breast cancer
    T L Klausen
    Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, Copenhagen, Denmark
    Clin Physiol Funct Imaging 25:196-202. 2005
    ..The aim of this investigation was to study the levels of this exposure in relation to the permissible radiation dose limits...
  70. ncbi [Sentinel lymphatic node biopsy for breast cancer in practice]
    P Strnad
    Gynekologicko porodnicka klinika, Klinika nukleární medicíny a Ustav patologické anatomie
    Ceska Gynekol 70:291-5. 2005
    ..This paper reviewed the feasibility and accuracy of sentinel lymph node status in women with breast cancer...
  71. ncbi Sentinel node biopsy in cutaneous melanoma
    Jørgen Lock-Andersen
    Department of Plastic Surgery, Roskilde Amts Sygehus Roskilde, Køgevej 7 13, DK 4000 Roskilde, Denmark
    Scand J Plast Reconstr Surg Hand Surg 40:24-31. 2006
    ..Using the presented technique, we found that SLNB was a useful procedure for staging patients with CMM and for selecting patients for more extensive metastatic screening and inclusion in trials of adjuvant treatments...
  72. ncbi 99mTc-phytate is better than 99mTc-human serum albumin as a radioactive tracer for sentinel lymph node biopsy in breast cancer
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, 818 Komuro, Ina machi, Kitaadachi, Saitama, 362 0806, Japan
    Surg Today 36:219-24. 2006
    ..We retrospectively compared the effectiveness of two radioactive agents, 99mTc-phytate and 99mTc-human serum albumin (HSA), when used in combination with blue dye...
  73. ncbi Excision biopsy of breast lesions changes the pattern of lymphatic drainage
    S H Estourgie
    Department of Surgery, Academic Medical Centre, Meibergdreef 9, Amsterdam, The Netherlands
    Br J Surg 94:1088-91. 2007
    ..The aim was to validate the sentinel node biopsy procedure in women who had previous breast excision biopsy by means of determining the reproducibility of lymphoscintigraphy after surgery...
  74. ncbi Intratumoral versus intraparenchymal injection technique for lymphoscintigraphy in breast cancer
    Susanne H Estourgie
    Departments of Surgery, The Netherlands Cancer Institute, Amsterdam, The Netherlands
    Clin Nucl Med 28:371-4. 2003
    ..This observation supports the authors' contention that lymphatic watersheds exist in the breast and highlights the importance of tracer administration into or close to the tumor...
  75. ncbi Peritumoural versus subareolar administration of technetium-99m nanocolloid for sentinel lymph node detection in breast cancer: preliminary results of a prospective intra-individual comparative study
    Sofiane Maza
    Clinic for Nuclear Medicine, University Hospital Charite, Humboldt University of Berlin, Berlin, Germany
    Eur J Nucl Med Mol Imaging 30:651-6. 2003
    ..9%. In conclusion, a simple subareolar injection in the clock position is sufficient for SN detection in breast cancer, if it is accepted that parasternal lymph node detection has no therapeutic consequences...
  76. ncbi Study of sentinel lymph node in breast cancer: our experience in 46 cases
    A Galli
    Surgery Department, Hospital of Biella, Italy
    Tumori 86:317-9. 2000
    ..The percentage of accuracy obtained in our study was 95.7%, which is slightly higher than the average of percentages of the case series abroad and in Italy...
  77. ncbi Preliminary study of sentinel node identification with 99mTc colloid and blue dye in patients with endometrial cancer
    E Pelosi
    Servizio de Medicina Nucleare Universitaria, Ospedale S Giovanni Batista, Turin, Italy
    Tumori 88:S9-10. 2002
    ..A 350 mm laparoscopic gamma scintyprobe MR 100 type 11, 99mTc settled (Pol Hi Tech), was used intraoperatively for SLN detection...
  78. ncbi Minimal sentinel node procedure for staging early breast cancer
    S Mariotti
    Division of Medical Oncology, University of Rome Tor Vergata, Italy
    Tumori 88:S45-7. 2002
    ..To minimize the extent of surgery, the feasibility of eradicating primary breast lesions and the relative sentinel lymph nodes (SLN) under regional anesthesia was evaluated in this study...
  79. ncbi Sentinel node detection with imaging probe
    O Schillaci
    Tor Vergata University, Rome, Italy
    Tumori 88:S32-5. 2002
    ..The operators' subjective impression of having detected the SLN was "absolutely sure" for 7/7 nodes with IP and "absolutely sure" for 5/7 nodes with Neoprobe...
  80. ncbi Recent applications of the sentinel lymph node concept: preliminary experience in prostate cancer
    M Rudoni
    Medicina Nucleare, Ospedale Maggiore Novara, Italy
    Tumori 88:S16-7. 2002
    ..The aims of this study were 1) to evaluate the accuracy of RGS in the detection of prostatic sentinel lymph nodes (SLN), and 2) to verify if pelvic lymphadenectomy (LAD) is an accurate means to detect solitary micrometastases...
  81. ncbi Sentinel node detection in breast carcinoma
    E Pelosi
    Servizio de Medicina Nucleare Universitario, Ospedale S Giovanni Battista, Turin, Italy
    Tumori 88:S10-1. 2002
    ..However, about 70% of patients are found to be free of metastatic disease while axillary node dissection may cause significant morbidity. Lymphatic mapping and sentinel lymph node (SLN) biopsy are changing this situation...
  82. ncbi Current practice and future directions in pathology and laboratory evaluation of the sentinel node
    A J Cochran
    Department of Pathology and Laboratory Medicine, and Jonsson Comprehensive Cancer Center, UCLA School of Medicine, Los Angeles, California 90095-1732, USA
    Ann Surg Oncol 8:13S-17S. 2001
    ..Studies are in progress to determine whether molecular biology techniques will detect additional nodes that contain truly occult tumor deposits...
  83. ncbi Gamma-detecting probe used intraoperatively to locate the sentinel lymph node in patients with malignant melanoma
    G Sugrañes
    Department of Surgery, Nuclear Medicine, University of Barcelona, Spain
    Eur J Surg 167:581-6. 2001
    ..To assess the usefulness of lymphoscintigraphy and intraoperative gamma probe in the detection of sentinel lymph nodes...
  84. ncbi Sentinel lymph node biopsy in breast cancer: the GIVOM experience in Veneto, Italy
    G Zavagno
    Clinica Chirurgica II, Universita di Padova, Italy
    Tumori 88:S52-4. 2002
  85. ncbi Subareolar injection for sentinel lymph node location in breast cancer
    Giorgio Zavagno
    Clinica Chirurgica II, University of Padova, Via Giustiniani 2, 35128, Padova, Italy
    Eur J Surg Oncol 28:701-4. 2002
    ..In order to test this hypothesis, we ascertained whether subareolar blue dye injection and subdermal radioisotope injection close to the tumour identify the same axillary nodes...
  86. ncbi Sentinel lymph node biopsy without axillary dissection after an intraoperative negative histological investigation in 358 invasive breast cancer cases
    Hiroyuki Takei
    Division of Breast Surgery, Saitama Cancer Center, 818 Ina machi, Kitaadachi, Saitama 362 0806, Japan
    Breast Cancer 9:344-8. 2002
    ..The present study shows the results and outcomes of SLNB as a sole procedure for patients with invasive breast cancer...
  87. ncbi Sentinel nodes outside level I-II of the axilla and staging in breast cancer
    R Rönkä
    Breast Surgery Unit, Maria Hospital, Helsinki University Hospital, Lapinlahdenkatu 16, 00029 HUS, Helsinki, Finland
    Anticancer Res 22:3109-12. 2002
    ..The aim of the study was to evaluate the incidence of sentinel nodes and sentinel node metastases outside levels I-II of the axilla in breast cancer...
  88. ncbi [SPECT-CT: a new tool for localisation of sentinel lymph nodes in breast cancer patients]
    J Mucientes Rasilla
    Servicio de Medicina Nuclear, Hospital Clinico San Carlos, Madrid, Espana
    Rev Esp Med Nucl 27:183-90. 2008
    ..Sentinel lymph node biopsy has become a widely accepted procedure for axillary lymph node staging in patients with breast cancer...
  89. ncbi An original approach in the diagnosis of early breast cancer: use of the same radiopharmaceutical for both non-palpable lesions and sentinel node localisation
    P J Tanis
    Eur J Nucl Med Mol Imaging 29:436-7; author reply 437-8. 2002
  90. ncbi Krypton-81m ventilation and technetium-99m macroaggregated albumin perfusion scintigraphy for detection of pulmonary embolism: the first experience in Taiwan
    S C Cherng
    Department of Nuclear Medicine, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC
    Zhonghua Yi Xue Za Zhi (Taipei) 63:876-84. 2000
    ..In addition, xenon (Xe)-133 ventilation scintigraphy was also performed for comparison...
  91. ncbi In-house preparation of technetium 99m-labeled human serum albumin for evaluation of protein-losing gastroenteropathy
    Joseph C Hung
    Nuclear Pharmacy Laboratories and PET Radiochemistry Facility, Department of Radiology, Mayo Clinic, Rochester, Minn 55905 0001, USA
    J Am Pharm Assoc (Wash) 42:57-62. 2002
    ..To develop an in-house preparation method for technetium 99m-labeled human serum albumin (99mTc-HSA) to meet the clinical need for gastrointestinal (GI) protein loss evaluation in our institution...
  92. ncbi Mapping the sentinel lymph node in malignant melanoma by blue dye, lymphoscintigraphy and intraoperative gamma probe
    G Villa
    Nuclear Medicine Service, DIMI, Genoa, Italy
    Tumori 86:343-5. 2000
    ..The latter all underwent SLND of the affected basin. In 10 patients (55.6%) the SN was the only site of tumor invasion; eight patients (44.4%) with positive SNs had one or more metastatic lymph nodes in the draining basin...
  93. ncbi Mammary lymphoscintigraphy with various radiopharmaceuticals in breast cancer
    S Imoto
    Division of Breast Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
    Ann Nucl Med 13:325-9. 1999
    ....
  94. ncbi [Right ventricular systolic and diastolic functions assessed by 81mKr scintigraphy and relation to ventricular septal ischemia]
    H Sugihara
    Second Department of Medicine, Kyoto Prefectural University of Medicine
    J Cardiol 17:607-15. 1987
    ..Similarly, diastolic function was maintained in mild septal ischemia, but impaired in severe septal ischemia. We concluded that RV systolic and diastolic functions are closely related to interventricular septal ischemia...
  95. ncbi Questionnaire survey of hospitals in Saitama Prefecture regarding the shortage of 99mTc-labeled radiopharmaceuticals and 99Mo/99mTc generators
    Shigeru Kosuda
    Department of Radiology, National Defense Medical College, 3 2 Namiki Tokorozawa, Saitama, 359 8513, Japan
    Ann Nucl Med 24:319-23. 2010
    ..6%) replied...
  96. pmc A unique case of collagenous colitis presenting as protein-losing enteropathy successfully treated with prednisolone
    Soichi Sano
    Department of Internal Medicine, Osaka City General Hospital, 2 13 22, Miyakojima ku, Osaka 534 0021, Japan
    World J Gastroenterol 14:6083-6. 2008
    ..Prednisolone treatment ameliorated diarrhea and hypoproteinemia. Collagenous colitis should be included in the differential diagnosis of chronic diarrhea with hypoproteinemia for appropriate management...
  97. ncbi A simplified procedure for continuous intraoperative external monitoring of systemic leakage during isolated limb perfusion
    D Casara
    Nuclear Medicine Service, Radiotherapy Department, University of Padua, Italy
    Tumori 88:S61-3. 2002
    ..Ten percent systemic leakage from the perfusion circuit is considered the maximum acceptable leakage. In this study we report our experience of a new leakage monitoring system...
  98. ncbi Radiopharmaceutical considerations for using Tc-99m MAA in lung transplant patients
    James A Ponto
    Division of Nuclear Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Dr, Iowa City, IA 52242, USA
    J Am Pharm Assoc (2003) 50:419-23. 2010
    ..To elucidate radiopharmaceutical considerations for using technetium Tc-99m albumin aggregated (Tc-99m MAA) in lung transplant patients and to establish an appropriate routine dose and preparation procedure...
  99. ncbi Biodistribution and imaging studies of technetium-99m-labeled liposomes in rats with focal infection
    B Goins
    Radiology Department, University of Texas Health Science Center at San Antonio 8284 7800
    J Nucl Med 34:2160-8. 1993
    ..3 +/- 7.6 for 99mTc-liposomes, 4.1 +/- 0.7 for 67Ga-citrate and 8.0 +/- 1.0 for 99mTc-HSA. These studies show the potential of using 99mTc-liposomes to localize infection...
  100. ncbi Effects of radiosynovectomy with p-32 colloid therapy in hemophilia and rheumatoid arthritis
    Victoria Ester Soroa
    Centro de Medicina Nuclear, Comision Nacional de Energía Atómica Argentina, Buenos Aires, IAEA, Argentina
    Cancer Biother Radiopharm 20:344-8. 2005
    ....
  101. ncbi Study of capillary filtration by double labelling I131-albumin and Tc99m red cells. Application to the pharmacodynamic activity of Daflon 500 mg
    A Behar
    , Paris, France
    Int Angiol 7:35-8. 1988
    ..01).(abstract truncated at 250 words)..

Research Grants6

  1. Oral Delivery of DNA Vaccines
    FRANK ORSON; Fiscal Year: 2003
    ....
  2. EVALUATION OF CARDIAC FUNCTION WITH RADIOACTIVE TRACERS
    Henry Wagner; Fiscal Year: 1980
    ..As a final step, the improved detection systems will be employed to record and evaluate left ventricular volume/time curves on patients routinely undergoing 99mTc-HSA blood pool imaging...
  3. Surrogate markers for Severe Pulmonary Embolism
    JEFFREY KLINE; Fiscal Year: 2005
    ..This study will determine if criteria that are widely and immediately available in most hospitals can be used to risk-stratify severity of PE and to clarify the role of nonmalignant thrombophilias on the prognosis of PE. ..
  4. Pretest Probability Assessment for Pulmonary Embolism
    JEFFREY KLINE; Fiscal Year: 2005
    ..In phase III, we will test the validity of the PE PREtest Consult TM and determine if the use of the PE PREtest ConsultTM will decrease unnecessary testing for PE. ..
  5. Dose and image quality in adult and pediatric CT
    Walter Huda; Fiscal Year: 2006
    ..Determine the choice of kVp/mAs and PR/mAs that minimize patient doses with no loss of diagnostic performance. 3. Help the Radiology community to balance the confliciting requirements of image quality and patient doses in clinical CT. ..
  6. Expired CO2/O2 Analysis to Diagnose Pulmonary Embolism
    JEFFREY KLINE; Fiscal Year: 2008
    ..This project will fund a clinical study designed to test the diagnostic accuracy of a hand- held breath device that detects the altered gas exchange physiology caused by PE in post-surgical and other patients at high risk for PE. ..