tetrachloroethylene

Summary

Summary: A chlorinated hydrocarbon used as an industrial solvent and cooling liquid in electrical transformers. It is a potential carcinogen.

Top Publications

  1. pmc Adverse birth outcomes and maternal exposure to trichloroethylene and tetrachloroethylene through soil vapor intrusion in New York State
    Steven P Forand
    Bureau of Environmental and Occupational Epidemiology, New York State Department of Health, Troy, New York 12180, USA
    Environ Health Perspect 120:616-21. 2012
  2. ncbi Tetrachloroethylene in drinking water and birth outcomes at the US Marine Corps Base at Camp Lejeune, North Carolina
    N Sonnenfeld
    Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA
    Am J Epidemiol 154:902-8. 2001
  3. pmc Occurrence of mental illness following prenatal and early childhood exposure to tetrachloroethylene (PCE)-contaminated drinking water: a retrospective cohort study
    Ann Aschengrau
    Department of Epidemiology, Boston University School of Public Health, Talbot 3E, 715 Albany Street, Boston, MA 02118, USA
    Environ Health 11:2. 2012
  4. pmc Affinity for risky behaviors following prenatal and early childhood exposure to tetrachloroethylene (PCE)-contaminated drinking water: a retrospective cohort study
    Ann Aschengrau
    Department of Epidemiology, Boston University School of Public Health, 715 Albany Street, Boston, MA 02118, USA
    Environ Health 10:102. 2011
  5. pmc Cancer in persons working in dry cleaning in the Nordic countries
    Elsebeth Lynge
    Institute of Public Health, University of Copenhagen, Copenhagen, Denmark
    Environ Health Perspect 114:213-9. 2006
  6. pmc Impact of tetrachloroethylene-contaminated drinking water on the risk of breast cancer: using a dose model to assess exposure in a case-control study
    Veronica Vieira
    Department of Epidemiology, Boston University School of Public Health, 715 Albany Street, Boston, MA 02118, USA
    Environ Health 4:3. 2005
  7. ncbi Impacts of microbial community composition on isotope fractionation during reductive dechlorination of tetrachloroethylene
    Yiran Dong
    Energy and Bioscience Institute, University of Illinois Urbana Champaign, Urbana, IL 61801, USA
    Biodegradation 22:431-44. 2011
  8. ncbi Visual contrast sensitivity in children exposed to tetrachloroethylene
    Jan E Storm
    Center for Environmental Health, New York State Department of Health, Troy, New York 12180, USA
    Arch Environ Occup Health 66:166-77. 2011
  9. pmc Geobacter lovleyi sp. nov. strain SZ, a novel metal-reducing and tetrachloroethene-dechlorinating bacterium
    Youlboong Sung
    Georgia Institute of Technology, School of Civil and Environmental Engineering, 311 Ferst Drive, 3228 ES and T Building, Atlanta, GA 30332 0512, USA
    Appl Environ Microbiol 72:2775-82. 2006
  10. ncbi [Stevens-Johnson syndrome accompanied by acute hepatitis in workers exposed to trichloroethylene or tetrachloroethylene]
    Naomi Hisanaga
    National Institute of Industrial Health, 6 21 1, Nagao, Tama ku, Kawasaki 214 8585, Japan
    Sangyo Eiseigaku Zasshi 44:33-49. 2002

Detail Information

Publications218 found, 100 shown here

  1. pmc Adverse birth outcomes and maternal exposure to trichloroethylene and tetrachloroethylene through soil vapor intrusion in New York State
    Steven P Forand
    Bureau of Environmental and Occupational Epidemiology, New York State Department of Health, Troy, New York 12180, USA
    Environ Health Perspect 120:616-21. 2012
    ..Previous studies have reported an increase in adverse birth outcomes among women exposed to VOCs in drinking water...
  2. ncbi Tetrachloroethylene in drinking water and birth outcomes at the US Marine Corps Base at Camp Lejeune, North Carolina
    N Sonnenfeld
    Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA
    Am J Epidemiol 154:902-8. 2001
    ..b>Tetrachloroethylene (PCE) was the predominant contaminant...
  3. pmc Occurrence of mental illness following prenatal and early childhood exposure to tetrachloroethylene (PCE)-contaminated drinking water: a retrospective cohort study
    Ann Aschengrau
    Department of Epidemiology, Boston University School of Public Health, Talbot 3E, 715 Albany Street, Boston, MA 02118, USA
    Environ Health 11:2. 2012
    ..This retrospective cohort study examined whether early life exposure to tetrachloroethylene (PCE)-contaminated drinking water influenced the occurrence of depression, bipolar disorder, post-traumatic ..
  4. pmc Affinity for risky behaviors following prenatal and early childhood exposure to tetrachloroethylene (PCE)-contaminated drinking water: a retrospective cohort study
    Ann Aschengrau
    Department of Epidemiology, Boston University School of Public Health, 715 Albany Street, Boston, MA 02118, USA
    Environ Health 10:102. 2011
    ..No prior study has investigated the long-term impact of prenatal and early childhood exposure to the solvent tetrachloroethylene (PCE) on the affinity for risky behaviors, defined as smoking, drinking or drug use as a teen or adult.
  5. pmc Cancer in persons working in dry cleaning in the Nordic countries
    Elsebeth Lynge
    Institute of Public Health, University of Copenhagen, Copenhagen, Denmark
    Environ Health Perspect 114:213-9. 2006
    U.S. studies have reported an increased risk of esophageal and some other cancers in dry cleaners exposed to tetrachloroethylene. We investigated whether the U.S...
  6. pmc Impact of tetrachloroethylene-contaminated drinking water on the risk of breast cancer: using a dose model to assess exposure in a case-control study
    Veronica Vieira
    Department of Epidemiology, Boston University School of Public Health, 715 Albany Street, Boston, MA 02118, USA
    Environ Health 4:3. 2005
    A population-based case-control study was undertaken in 1997 to investigate the association between tetrachloroethylene (PCE) exposure from public drinking water and breast cancer among permanent residents of the Cape Cod region of ..
  7. ncbi Impacts of microbial community composition on isotope fractionation during reductive dechlorination of tetrachloroethylene
    Yiran Dong
    Energy and Bioscience Institute, University of Illinois Urbana Champaign, Urbana, IL 61801, USA
    Biodegradation 22:431-44. 2011
    ..cultures prepared from uncontaminated sediments influenced the extent of isotope fractionation of tetrachloroethylene (PCE), either directly, or through its influence on microbial community composition...
  8. ncbi Visual contrast sensitivity in children exposed to tetrachloroethylene
    Jan E Storm
    Center for Environmental Health, New York State Department of Health, Troy, New York 12180, USA
    Arch Environ Occup Health 66:166-77. 2011
    This study examined relationships between indoor air, breath, and blood tetrachloroethylene (perc) levels and visual contrast sensitivity (VCS) among adult and child residents of buildings with or without a colocated dry cleaner using ..
  9. pmc Geobacter lovleyi sp. nov. strain SZ, a novel metal-reducing and tetrachloroethene-dechlorinating bacterium
    Youlboong Sung
    Georgia Institute of Technology, School of Civil and Environmental Engineering, 311 Ferst Drive, 3228 ES and T Building, Atlanta, GA 30332 0512, USA
    Appl Environ Microbiol 72:2775-82. 2006
    ..Substrate versatility, consumption of electron donors to low threshold concentrations, and simultaneous reduction of electron acceptors suggest that strain SZ-type organisms have desirable characteristics for bioremediation applications...
  10. ncbi [Stevens-Johnson syndrome accompanied by acute hepatitis in workers exposed to trichloroethylene or tetrachloroethylene]
    Naomi Hisanaga
    National Institute of Industrial Health, 6 21 1, Nagao, Tama ku, Kawasaki 214 8585, Japan
    Sangyo Eiseigaku Zasshi 44:33-49. 2002
    ..although the number is small, a similar health disorder has also occurred in workers using tetrachloroethylene. Since the above-mentioned facts are not yet well recognized in the occupational health community, this ..
  11. ncbi Analysis and comparison of the microbial community structures of two enrichment cultures capable of reductively dechlorinating TCE and cis-DCE
    April Z Gu
    Department of Civil and Environmental Engineering, University of Washington, Seattle, 98195, USA
    Environ Microbiol 6:45-54. 2004
    ....
  12. pmc Prenatal and early childhood exposure to tetrachloroethylene and adult vision
    Kelly D Getz
    Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA
    Environ Health Perspect 120:1327-32. 2012
    b>Tetrachloroethylene (PCE; or perchloroethylene) has been implicated in visual impairments among adults with occupational and environmental exposures as well as children born to women with occupational exposure during pregnancy.
  13. ncbi Revisiting the population toxicokinetics of tetrachloroethylene
    Weihsueh A Chiu
    Arch Toxicol 80:382-5. 2006
  14. ncbi Complete reductive dechlorination of tetrachloroethene to ethene by anaerobic microbial enrichment culture developed from sediment
    Byung Hyuk Kim
    Environmental Biotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology KRIBB, Daejeon, 305 333, Republic of Korea
    Biotechnol Lett 32:1829-35. 2010
    ..Geobacter lovleyi and a Dehalococcoides sp. were identified from their 16S rRNA sequences to be the dominant phylotypes in AMEC-4P...
  15. pmc Prenatal exposure to tetrachloroethylene-contaminated drinking water and the risk of congenital anomalies: a retrospective cohort study
    Ann Aschengrau
    Department of Epidemiology, Boston University School of Public Health, Talbot 3E, 715 Albany Street, Boston, MA 02118, USA
    Environ Health 8:44. 2009
    Prior animal and human studies of prenatal exposure to solvents including tetrachloroethylene (PCE) have shown increases in the risk of certain congenital anomalies among exposed offspring.
  16. pmc Adult neuropsychological performance following prenatal and early postnatal exposure to tetrachloroethylene (PCE)-contaminated drinking water
    Patricia A Janulewicz
    Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA
    Neurotoxicol Teratol 34:350-9. 2012
    ..on a battery of neuropsychological tests in relation to prenatal and early postnatal exposure to tetrachloroethylene (PCE)-contaminated drinking water on Cape Cod, Massachusetts...
  17. ncbi Neurotoxicologic examination of rats exposed to 1,1,2,2-tetrachloroethylene (perchloroethylene) vapor for 13 weeks
    J L Mattsson
    Health and Environmental Research Laboratories, Dow Chemical Company, Midland, MI 48674, USA
    Neurotoxicol Teratol 20:83-98. 1998
    ..and EEG changes occurred in a pilot study in Fischer 344 rats during exposure to 800 ppm of 1,1,2,2-tetrachloroethylene [perchloroethylene (Perc)], a cleaning solvent with anesthetic properties...
  18. ncbi Enhanced degradation of tetrachloroethylene by green rusts with platinum
    Jeongyun Choi
    R and D Center, Samsung Engineering Co, LTD 415 10, Wancheon Dong, Youngtong Gu, Suwan city 443 823, South Korea
    Environ Sci Technol 42:3356-62. 2008
    This study presents an experiment which characterizes reductive dechlorination of tetrachloroethylene (PCE) by green rusts (GRs) in the presence of Pt using a batch reactor system...
  19. ncbi Effect of metal ions and humic acid on the dechlorination of tetrachloroethylene by zerovalent iron
    Ruey An Doong
    Department of Atomic Science, National Tsing Hua University, 101, Sec 2, Kuang Fu Road, Hsinchu 30013, Taiwan, ROC
    Chemosphere 64:371-8. 2006
    The dechlorination of tetrachloroethylene (PCE) by zerovalent iron (Fe(0)) in the presence of metal ions and humic acid was investigated...
  20. ncbi Effect of petroleum derivatives and solvents on colour perception
    - Sharanjeet-Kaur
    Department of Optometry, Faculty of Allied Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Malaysia
    Clin Exp Optom 87:339-43. 2004
    ..This study was undertaken to determine the effect of exposure to petroleum derivatives (polyethylene, polystyrene) and solvents (perchloroethylene) on colour perception...
  21. ncbi Reductive dechlorination of tetrachloroethylene and trichloroethylene by mackinawite (FeS) in the presence of metals: reaction rates
    Hoon Y Jeong
    Department of Civil and Environmental Engineering, University of Michigan, Ann Arbor, Michigan 48109 2125, Ann Arbor, Michigan 48109 1063, USA
    Environ Sci Technol 41:6390-6. 2007
    ..The dechlorination rates of PCE and TCE significantly varied with Fe(ll) amendment concentrations (Fe(II)0), indicating the presence of different types of solid-bound Fe phases with Fe(II)o...
  22. ncbi Kinetic and isotope analyses of tetrachloroethylene and trichloroethylene degradation by model Fe(II)-bearing minerals
    Xiaoming Liang
    School of Civil Engineering and Environmental Science, University of Oklahoma, Norman, OK 73019, USA
    Chemosphere 75:63-9. 2009
    ..and in some cases stable carbon isotope fractionation associated with abiotic reductive dechlorination of tetrachloroethylene (PCE) and trichloroethylene (TCE) by model Fe(II)-bearing minerals present in anaerobic soils were measured...
  23. pmc Characterization of two tetrachloroethene-reducing, acetate-oxidizing anaerobic bacteria and their description as Desulfuromonas michiganensis sp. nov
    Youlboong Sung
    School of Civil and Environmental Engineering School of Biology, Georgia Institute of Technology, 311 Ferst Drive, Atlanta, GA 30332 0512, USA
    Appl Environ Microbiol 69:2964-74. 2003
    ....
  24. pmc Acute liver failure associated with occupational exposure to tetrachloroethylene
    Chuan Shen
    Department of Infectious Disease, The Third Affiliated Hospital, Hebei Medical University, Shijiazhuang, China
    J Korean Med Sci 26:138-42. 2011
    b>Tetrachloroethylene is a chlorinated solvent that is primarily used in dry cleaning and degreasing operations...
  25. ncbi DNA damage detected by the alkaline comet assay in the liver of mice after oral administration of tetrachloroethylene
    Håkan Cederberg
    Swedish Chemicals Agency, PO Box 2, S 172 13 Sundbyberg, Sweden
    Mutagenesis 25:133-8. 2010
    ..and kidney of male CD1 mice was studied by means of the alkaline Comet assay after oral administration of tetrachloroethylene at the doses of 1000 and 2000 mg/kg/day...
  26. ncbi Quantification of perchloroethylene residues in dry-cleaned fabrics
    Katy S Sherlach
    Department of Chemistry, Georgetown University, Washington, DC, USA
    Environ Toxicol Chem 30:2481-7. 2011
    ..Measured differences across dry-cleaning establishments and fabric type suggest more vigorous monitoring of PCE residues may be warranted. Environ. Toxicol. Chem. 2011;30:2481-2487. © 2011 SETAC...
  27. ncbi The relative contributions of abiotic and microbial processes to the transformation of tetrachloroethylene and trichloroethylene in anaerobic microcosms
    Yiran Dong
    School of Civil Engineering and Environmental Science, Department of Botany and Microbiology, University of Oklahoma, Norman, Oklahoma 73019, USA
    Environ Sci Technol 43:690-7. 2009
    Reductive dechlorination of tetrachloroethylene (PCE) and trichloroethylene (TCE) was studied in well-defined microcosms prepared with aquifer materials from three locations...
  28. ncbi Aerobic degradation of mixtures of tetrachloroethylene, trichloroethylene, dichloroethylenes, and vinyl chloride by toluene-o-xylene monooxygenase of Pseudomonas stutzeri OX1
    H Shim
    Department of Chemical Engineering, University of Connecticut, Storrs, 06269-3222, USA
    Appl Microbiol Biotechnol 56:265-9. 2001
    ..monooxygenase (ToMO) of Pseudomonas stutzeri OX1 degraded binary mixtures (100 microM each) of tetrachloroethylene (PCE) with either trichloroethylene (TCE), 1,1-dichloroethylene (1,1-DCE), cis-dichloroethylene (cis-DCE), ..
  29. pmc Prenatal exposure to tetrachloroethylene-contaminated drinking water and the risk of adverse birth outcomes
    Ann Aschengrau
    Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts 02118, USA
    Environ Health Perspect 116:814-20. 2008
    Prior studies of prenatal exposure to tetrachloroethylene (PCE) have shown mixed results regarding its effect on birth weight and gestational age.
  30. pmc Graphite electrode as a sole electron donor for reductive dechlorination of tetrachlorethene by Geobacter lovleyi
    Sarah M Strycharz
    Department of Microbiology, University of Massachusetts, Amherst, Massachusetts, USA
    Appl Environ Microbiol 74:5943-7. 2008
    ....
  31. ncbi Systematic literature review of uses and levels of occupational exposure to tetrachloroethylene
    Laura S Gold
    Department of Epidemiology, University of Washington, Seattle, Washington 98195, USA
    J Occup Environ Hyg 5:807-39. 2008
    b>Tetrachloroethylene has been one of the most widely used chlorinated solvents in the United States. This review provides a basis for tetrachloroethylene exposure assessment in population-based case-control studies...
  32. ncbi Color vision: a sensitive indicator of exposure to neurotoxins
    F Gobba
    Dipartimento di Scienze Igienistiche, Microbiologiche e Biostatistiche, Universita di Modena e Reggio Emilia, Modena, Italy
    Neurotoxicology 21:857-62. 2000
    ....
  33. pmc Detection and quantification of Geobacter lovleyi strain SZ: implications for bioremediation at tetrachloroethene- and uranium-impacted sites
    Benjamin K Amos
    School of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, GA 30332 0512, USA
    Appl Environ Microbiol 73:6898-904. 2007
    ..The G. lovleyi strain SZ-specific tools will be useful for monitoring bioremediation efforts at uranium- and/or chlorinated solvent-impacted sites such as the Oak Ridge IFC site...
  34. ncbi Hepatic and renal toxicities associated with perchloroethylene
    L H Lash
    Department of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan 48201 1928, USA
    Pharmacol Rev 53:177-208. 2001
    ..Finally, the epidemiological and experimental data are assessed and use of toxicity information in the development of a reference dose and a reference concentration for human Perc exposure are presented...
  35. ncbi Phylogenetic analysis of bacterial populations in an anaerobic microbial consortium capable of degrading saturation concentrations of tetrachloroethylene
    Philip C Dennis
    Department of Civil Engineering, University of Toronto, 35 St George St, Toronto, ON M5S 1A4, Canada
    Can J Microbiol 49:15-27. 2003
    ..A Trichlorobacter species was detected where PCE concentrations were highest, up to 85 cm from the PCE source, whereas D. ethenogenes was ubiquitous to over 128 cm from the PCE source...
  36. ncbi Spatial and temporal distributions of Geobacter lovleyi and Dehalococcoides spp. during bioenhanced PCE-NAPL dissolution
    Benjamin K Amos
    School of Civil and Environmental Engineering, Georgia Institute of Technology, 311 Ferst Drive, Atlanta, Georgia 30332 0512, USA
    Environ Sci Technol 43:1977-85. 2009
    ..The results from this study highlight that bioenhanced dissolution is governed by a complex interplay between resident dechlorinators, contaminant concentrations, and other aquifer-specific characteristics (e.g., hydrology)...
  37. pmc Risk of breast cancer following exposure to tetrachloroethylene-contaminated drinking water in Cape Cod, Massachusetts: reanalysis of a case-control study using a modified exposure assessment
    Lisa G Gallagher
    Department of Environmental Health, Boston University School of Public Health, 715 Albany Street, Talbot 4 West, Boston, MA 02118, USA
    Environ Health 10:47. 2011
    b>Tetrachloroethylene (PCE) is an important occupational chemical used in metal degreasing and drycleaning and a prevalent drinking water contaminant...
  38. ncbi Early lifestage exposure and potential developmental susceptibility to tetrachloroethylene
    Rebecca Brown Dzubow
    National Center for Environmental Assessment, Office of Research and Development, US Environmental Protection Agency, Mailcode 8623 P, Washington, DC 20460, USA
    Birth Defects Res B Dev Reprod Toxicol 89:50-65. 2010
    b>Tetrachloroethylene, also known as perchloroethylene or "perc", is a highly volatile and lipophilic solvent widely used in dry cleaning, textile processing, and metal-cleaning operations...
  39. pmc Risk of learning and behavioral disorders following prenatal and early postnatal exposure to tetrachloroethylene (PCE)-contaminated drinking water
    Patricia A Janulewicz
    Department of Environmental Health, Boston University School of Public Health, Boston Massachusetts 02118, USA
    Neurotoxicol Teratol 30:175-85. 2008
    ..disorders of learning, attention and behavior and prenatal and early postnatal drinking water exposure to tetrachloroethylene (PCE) on Cape Cod, Massachusetts. Subjects were identified through birth records from 1969 through 1983...
  40. ncbi Long-term perchloroethylene exposure: a meta-analysis of neurobehavioral deficits in occupationally and residentially exposed groups
    Vernon A Benignus
    Human Studies Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    J Toxicol Environ Health A 72:824-31. 2009
    ....
  41. ncbi Occupational exposure to perchloroethylene in dry-cleaning shops in Tehran, Iran
    Seyed Reza Azimi Pirsaraei
    Occupational Health Department, Faculty of Health and Paramedical Sciences, Zanjan University of Medical Sciences, Parvin Etesaami Ave, Post of Code 4515786349, Zanjan, Iran
    Ind Health 47:155-9. 2009
    ..The results also showed the potential utility of measuring the concentration of perchloroethylene in end-exhaled air as a method for assessing relative exposure in dry cleaning shops which use it...
  42. pmc In silico toxicology: simulating interaction thresholds for human exposure to mixtures of trichloroethylene, tetrachloroethylene, and 1,1,1-trichloroethane
    Ivan D Dobrev
    Quantitative and Computational Toxicology Group, Center for Environmental Toxicology and Technology, Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado 80523, USA
    Environ Health Perspect 110:1031-9. 2002
    ..Evaluation of metabolic interactions and their thresholds illustrates a unique application of PBPK modeling in risk assessment of occupational exposures to chemical mixtures...
  43. pmc Biological exposure assessment to tetrachloroethylene for workers in the dry cleaning industry
    Lauralynn T McKernan
    Centers for Disease Control and Prevention CDC National Institute for Occupational Safety and Health, 4676 Columbia Parkway, R 15, Cincinnati, OH 45226, USA
    Environ Health 7:12. 2008
    The purpose of this study was to assess the feasibility of conducting biological tetrachloroethylene (perchloroethylene, PCE) exposure assessments of dry cleaning employees in conjunction with evaluation of possible PCE health effects.
  44. ncbi A small amount of tetrachloroethylene ingestion from drinking water accelerates antigen-stimulated allergic responses
    Makoto Seo
    Laboratory of Hygienics, Gifu Pharmaceutical University, Gifu, Japan
    Immunobiology 213:663-9. 2008
    Previously, we observed that tetrachloroethylene (perchloroethylene, PCE) increased histamine release and inflammatory mediator production from antigen-stimulated mast cells...
  45. ncbi Assessing interaction thresholds for trichloroethylene in combination with tetrachloroethylene and 1,1,1-trichloroethane using gas uptake studies and PBPK modeling
    I D Dobrev
    Center for Environmental Toxicology and Technology, Department of Environmental Health, Colorado State University, Fort Collins 80523, USA
    Arch Toxicol 75:134-44. 2001
    The volatile organic solvents trichloroethylene (TCE), tetrachloroethylene (perchloroethylene, PERC), and 1,1,1-trichloroethane (methylchloroform, MC) are widely distributed environmental pollutants and common contaminants of many ..
  46. ncbi Reductive dehalogenation of tetrachloroethylene by microorganisms: current knowledge and application strategies
    G Chen
    Crop and Soil Sciences, Washington State University, Pullman, WA 99164, USA
    Appl Microbiol Biotechnol 63:373-7. 2004
    ..However, due to the role of acetate, expected dehalogenating results cannot be obtained and unexpected methane formation can be encountered in practice...
  47. pmc Use of history science methods in exposure assessment for occupational health studies
    K Johansen
    Institute of Public Health, University of Copenhagen, Blegdamsvej 3, DK 2200 Copenhagen N, Denmark
    Occup Environ Med 62:434-41. 2005
    ..To show the power of history science methods for exposure assessment in occupational health studies, using the dry cleaning industry in Denmark around 1970 as the example...
  48. ncbi Tetrachloroethylene and trichloroethylene fatality: case report and simple headspace SPME-capillary gas chromatographic determination in tissues
    B Dehon
    Unité Fonctionnelle de Toxicologie, Laboratoire de Biochimie et de Biologie Moleculaire, Lille, France
    J Anal Toxicol 24:22-6. 2000
    We describe a simple, precise, and sensitive assay of tetrachloroethylene and trichloroethylene in tissues, suitable both for emergency cases and forensic medicine...
  49. pmc Tetrachloroethylene (PCE, Perc) levels in residential dry cleaner buildings in diverse communities in New York City
    Michael J McDermott
    Center for Environmental Health, New York State Department of Health, Troy, New York, USA
    Environ Health Perspect 113:1336-43. 2005
    Fugitive tetrachloroethylene (PCE, perc) emissions from dry cleaners operating in apartment buildings can contaminate residential indoor air...
  50. pmc Tetrachloroethylene-contaminated drinking water and the risk of breast cancer
    A Aschengrau
    Department of Epidemiology, University School of Public Health, Boston, Massachusetts, USA
    Environ Health Perspect 106:947-53. 1998
    ..case-control study to evaluate the relationship between cases of breast cancer and exposure to tetrachloroethylene (PCE) from public drinking water ( n = 258 cases and 686 controls)...
  51. ncbi Mortality in dry-cleaning workers: an update
    A M Ruder
    National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
    Am J Ind Med 39:121-32. 2001
    ..Many workers also had exposure to Stoddard solvent, a petroleum-based dry-cleaning solvent...
  52. ncbi Effect of perchloroethylene, smoking, and race on oxidative DNA damage in female dry cleaners
    Mark Toraason
    The National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
    Mutat Res 539:9-18. 2003
    ..Results indicate a reduction in oxidative DNA damage in PERC exposed dry cleaners relative to launderers, but PERC could not clearly be defined as the source of the effect...
  53. ncbi Estimating risk during showering exposure to VOCs of workers in a metal-degreasing facility
    Amaya Franco
    Department of Chemical Engineering, Institute of Technology, University of Santiago de Compostela, santiago de composa
    J Toxicol Environ Health A 70:627-37. 2007
    ..The results showed that dermal exposure to trichloroethylene (TCE) and tetrachloroethylene (perchloroethylene, PCE) represented the main contribution to total risk...
  54. pmc Perchloroethylene-contaminated drinking water and the risk of breast cancer: additional results from Cape Cod, Massachusetts, USA
    Ann Aschengrau
    Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA
    Environ Health Perspect 111:167-73. 2003
    ..results of a study suggesting an association between breast cancer and perchloroethylene (PCE; also called tetrachloroethylene) exposure from public drinking water...
  55. ncbi Assessing occupational exposure to perchloroethylene in dry cleaning
    Julia von Grote
    Institute for Chemical and Bioengineering, Swiss Federal Institute of Technology, Zurich, Switzerland
    J Occup Environ Hyg 3:606-19. 2006
    ..The results from the scenario-based analysis are consistent with exposure ranges obtained from a Monte Carlo calculation using frequency distributions of key input parameters, such as emission factors, batch times, and room volumes...
  56. ncbi Confronting workplace exposure to chemicals with LCA: examples of trichloroethylene and perchloroethylene in metal degreasing and dry cleaning
    Stefanie Hellweg
    Swiss Federal Institute of Technology, Safety and Environmental Technology Group, ETH Honggerberg, CH 8093 Zurich, Switzerland
    Environ Sci Technol 39:7741-8. 2005
    ..We therefore conclude that occupational health effects need to be considered in LCA to prevent overlooking key environmental-health impacts in LCA...
  57. ncbi Perchloroethylene in alveolar air, blood, and urine as biologic indices of low-level exposure
    Fabriziomaria Gobba
    Dipartimento di Scienze Igienistiche, Universita di Modena e Reggio Emilia, Modena, Italy
    J Occup Environ Med 45:1152-7. 2003
    ..PCE-Alv offers some advantages because it correlated better with exposure and is analytically simpler...
  58. ncbi Tetrachloroethylene emissions and exposure in dry cleaning
    J Raisanen
    Department of Physics, Finnish Institute of Occupational Health, Helsinki
    J Air Waste Manag Assoc 51:1671-5. 2001
    b>Tetrachloroethylene (PCE) emissions and the exposure of workers in six commercial and three industrial dry-cleaning establishments that use dry-to-dry machines were determined...
  59. ncbi Critical review of the epidemiological literature on occupational exposure to perchloroethylene and cancer
    Kenneth A Mundt
    Applied Epidemiology, Inc, Amherst, Massachusetts 01002 2424, USA
    Int Arch Occup Environ Health 76:473-91. 2003
    ..With regard to occupational exposure through dry-cleaning, PCE is considered to be possibly carcinogenic to humans. This review was conducted to assess the current epidemiological literature on PCE and specific cancers...
  60. ncbi Metalloporphyrin solubility: a trigger for catalyzing reductive dechlorination of tetrachloroethylene
    Ishai Dror
    Clemson Institute of Environmental Toxicology, Clemson University, Pendleton, South Carolina 29670, USA
    Environ Toxicol Chem 23:252-7. 2004
    ..metalloporphyrin solubility is a key factor in their ability to catalyze the reductive dechlorination of tetrachloroethylene and its daughter compounds...
  61. ncbi Dechlorination of tetrachloroethylene by palladized iron in the presence of humic acid
    Ruey An Doong
    Department of Atomic Science, National Tsing Hua University, 101, Sec 2, Kuang Fu Road, Hsinchu, Taiwan
    Water Res 39:2309-18. 2005
    The dechlorination of tetrachloroethylene (PCE) by palladized irons in the presence of humic acid was investigated to understand the feasibility of using Pd/Fe for the in situ remediation of contaminated groundwater...
  62. ncbi Reductive dechlorination of carbon tetrachloride and tetrachloroethylene by zerovalent silicon-iron reductants
    Ruey An Doong
    Department of Atomic Science, National Tsing Hua University, Hsinchu 30013, Taiwan
    Environ Sci Technol 37:2575-81. 2003
    Reductive dechlorination of carbon tetrachloride (CT) and tetrachloroethylene (PCE) by zerovalent silicon (ZVS, Si0) and the combination of Si0 with metal iron (Fe0) was investigated as potential reductants for chlorinated hydrocarbons...
  63. ncbi Amendment of hydroxyapatite in reduction of tetrachloroethylene by zero-valent zinc: its rate enhancing effect and removal of Zn(II)
    Hocheol Song
    Korea Institute of Geoscience and Mineral Resources, Daejeon 305 350, South Korea
    Chemosphere 73:1420-7. 2008
    The effects of hydroxyapatite (HAP) on dechlorination of tetrachloroethylene (PCE) by zero-valent zinc (ZVZ) were examined in batch systems...
  64. ncbi Surfactant enhanced recovery of tetrachloroethylene from a porous medium containing low permeability lenses. 1. Experimental studies
    T P Taylor
    School of Civil and Environmental Engineering, Georgia Institute of Technology, 200 Bobby Dodd Way, Atlanta, GA 30332 0512, USA
    J Contam Hydrol 48:325-50. 2001
    ..solubilization and layering on the entrapment and subsequent recovery of a representative dense NAPL, tetrachloroethylene (PCE), during surfactant flushing...
  65. ncbi Reductive dechlorination pathways of tetrachloroethylene and trichloroethylene and subsequent transformation of their dechlorination products by mackinawite (FeS) in the presence of metals
    Hoon Y Jeong
    Department of Civil and Environmental Engineering, University of Michigan, Ann Arbor, Michigan 48109 2125, USA
    Environ Sci Technol 41:7736-43. 2007
    ..Although nearly complete mass recoveries were observed in the other FeS batches, the subsequent transformation of acetylene would lead to the formation of unidentified product(s) over long time periods...
  66. ncbi Role of metalloporphyrin core metals in the mediated reductive dechlorination of tetrachloroethylene
    Ishai Dror
    Department of Agricultural and Biological Engineering, Clemson University, Clemson, South Carolina 29634 0357, USA
    Environ Toxicol Chem 22:525-33. 2003
    ..approaches were used to elucidate the role of porphyrin core metals in the reductive dechlorination of tetrachloroethylene (PCE)...
  67. ncbi Functional characterization of the trigger factor protein PceT of tetrachloroethene-dechlorinating Desulfitobacterium hafniense Y51
    Yasuyuki Morita
    Department of Bioscience and Biotechnology, Kyushu University, Fukuoka, Japan
    Appl Microbiol Biotechnol 83:775-81. 2009
    ..On the other hand, PceT failed to bind the mature form of PceA that lost the TAT signal sequence. This is the first report in dehalorespiring bacteria, indicating that PceT is responsible for the correct folding of the precursor PceA...
  68. ncbi A control technology evaluation of state-of-the-art, perchloroethylene dry-cleaning machines
    G Scott Earnest
    National Institute for Occupational Safety and Health, Division of Applied Research and Technology, Cincinnati, OH, USA
    Appl Occup Environ Hyg 17:352-9. 2002
    ....
  69. pmc Apartment residents' and day care workers' exposures to tetrachloroethylene and deficits in visual contrast sensitivity
    Judith S Schreiber
    State of New York, Office of Attorney General, Albany, New York, USA
    Environ Health Perspect 110:655-64. 2002
    b>Tetrachloroethylene (also called perchloroethylene, or perc), a volatile organic compound, has been the predominant solvent used by the dry-cleaning industry for many years. The U.S...
  70. pmc Tetrachloroethylene exposure and risk of schizophrenia: offspring of dry cleaners in a population birth cohort, preliminary findings
    Mary C Perrin
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, 10032, USA
    Schizophr Res 90:251-4. 2007
    b>Tetrachloroethylene is a solvent used in dry cleaning with reported neurotoxic effects...
  71. pmc Evaluation of the Webler-Brown model for estimating tetrachloroethylene exposure from vinyl-lined asbestos-cement pipes
    Lisa A Spence
    Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA
    Environ Health 7:24. 2008
    ..The vinyl resin was applied to the inner pipe surface in a solution of tetrachloroethylene (perchloroethylene, PCE)...
  72. pmc Update of residential tetrachloroethylene exposure and decreases in visual contrast sensitivity
    Jan E Storm
    Environ Health Perspect 112:A862-4; author reply A864-5. 2004
  73. ncbi Tetrachloroethylene, trichloroethylene, and chlorinated phenols induce toluene-o-xylene monooxygenase activity in Pseudomonas stutzeri OX1
    D Ryoo
    Department of Chemical Engineering, University of Connecticut, Storrs 06269-3222, USA
    Appl Microbiol Biotechnol 56:545-9. 2001
    Pseudomonas stutzeri OX1 naphthalene-oxidation activity is induced 3.0-fold by tetrachloroethylene (PCE) and 3.1-fold by trichloroethylene (TCE) at 100 microM. With the mutant P...
  74. ncbi Surfactant enhanced recovery of tetrachloroethylene from a porous medium containing low permeability lenses. 2. Numerical simulation
    K M Rathfelder
    Department of Civil and Environmental Engineering, The University of Michigan, 1351 Beal Avenue, Ann Arbor, MI 48109-2125, USA
    J Contam Hydrol 48:351-74. 2001
    ..Model predictive capability was assessed for the evaluation of the micellar solubilization of tetrachloroethylene (PCE) in the two-dimensional systems...
  75. ncbi Concordance across species in the reproductive and developmental toxicity of tetrachloroethylene
    Robert P Beliles
    Toxicol Ind Health 18:91-106. 2002
    Reproductive and developmental toxicities resulting from exposure to tetrachloroethylene include delayed or impaired conception, sperm quality, death during development, developmental neurotoxicity, and growth retardation...
  76. ncbi Micellar partitioning and its effects on Henry's law constants of chlorinated solvents in anionic and nonionic surfactant solutions
    Chunlong Zhang
    Department of Environmental Sciences, University of Houston Clear Lake, 2700 Bay Area Blvd, Houston, Texas 77058, USA
    Environ Sci Technol 40:208-14. 2006
    ..coefficients (Km) and apparent Henry's law constants (H*) of three prominent groundwater contaminants (tetrachloroethylene, trichloroethylene, cis-dichlorethylene) in the presence of two anionic surfactants (sodium dodecyl sulfate,..
  77. ncbi Dissolution of an emplaced source of DNAPL in a natural aquifer setting
    Michael O Rivett
    School of Geography, Earth and Environmental Sciences, University of Birmingham, Birmingham B15 2TT, UK
    Environ Sci Technol 39:447-55. 2005
    ..Our dissolution interpretations were endorsed by additional data collected after 6 yr during source remediation via permanganate oxidation...
  78. ncbi Measuring hydrophobic micropore volumes in geosorbents from trichloroethylene desorption data
    Hefa Cheng
    Department of Civil and Environmental Engineering, Stanford University, Stanford, California 94305 4020, USA
    Environ Sci Technol 40:3595-602. 2006
    ..The results suggest that hydrolyzable organic contaminants sorbed in hydrophobic micropores react slower than in bulk water, consistent with the reported persistence of reactive contaminants in natural soils...
  79. ncbi Assessment of natural or enhanced in situ bioremediation at a chlorinated solvent-contaminated aquifer in Italy: a microcosm study
    Federico Aulenta
    Department of Chemistry, University of Rome La Sapienza, P le Aldo Moro 5, 00185 Rome, Italy
    Environ Int 31:185-90. 2005
    ..g., lactate or butyrate) and/or through bioaugmentation with a Dehalococcoides-containing culture...
  80. ncbi [Trichloroacetic acid and trichloroethanol in urine]
    Hideki Igisu
    Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health
    Nihon Rinsho 62:479-81. 2004
  81. ncbi Quantification of groundwater contamination in an urban area using integral pumping tests
    S Bauer
    Center for Applied Geoscience, Institute for Geoscience, University of Tubingen, Sigwartstrasse 10, D 72076 Tubingen, Germany
    J Contam Hydrol 75:183-213. 2004
    ..Additionally, large parts of the area investigated could be excluded from further investigation and remediation activities...
  82. ncbi Biodegradation of PCE and TCE in landfill leachate predicted from concentrations of molecular hydrogen: a case study
    Mary E Gonsoulin
    US Environmental Protection Agency, Robert Kerr Research Laboratory, OK 74820, USA
    Biodegradation 15:475-85. 2004
    ..38 to 0.18 per year. In wells without adequate hydrogen the rate varies from 0.015 to 0.006 per year...
  83. ncbi Complete biological dehalogenation of chlorinated ethylenes in sulfate containing groundwater
    T P Hoelen
    Department of Civil and Environmental Engineering, Stanford University, Stanford, CA 94305 4020, USA
    Biodegradation 15:395-403. 2004
    ..Dehalogenation was inhibited in soil free microcosms containing 5 mM sulfide, but inhibition was not observed when either aquifer sediment or 5 mM ferrous chloride was added...
  84. ncbi Mass and flux distributions from DNAPL zones in sandy aquifers
    Martin A Guilbeault
    Department of Earth Sciences, University of Waterloo, Waterloo, Ontario N2L 3G1 Canada
    Ground Water 43:70-86. 2005
    At three industrial sites in Ontario, New Hampshire, and Florida, tetrachloroethylene (PCE) and trichloroethylene (TCE), released decades ago as dense nonaqueous phase liquids (DNAPLs), now form persistent source zones for dissolved ..
  85. ncbi A shift in pathway of iron-mediated perchloroethylene reduction in the presence of sorbed surfactant--a column study
    Zhaohui Li
    Department of Geosciences, University of Wisconsin Parkside, 900 Wood Road, Kenosha, WI 53141, USA
    Water Res 40:3811-9. 2006
    ..Although this shift in reaction pathway resulted in a higher accumulation of TCE, the combined concentrations of chlorinated hydrocarbons in the effluent were 1.5-5 times lower when SM-ZVI rather than unmodified ZVI was used...
  86. ncbi [Exposure to organic halogen compounds in drinking water of 9 Italian regions: exposure to chlorites, chlorates, thrihalomethanes, trichloroethylene and tetrachloroethylene]
    G Fantuzzi
    Dipartimento de Scienze di Sanità Pubblica, Facoltà di Bioscienze e Biotecnologie, Universita di Modena e Reggio Emilia
    Ann Ig 19:345-54. 2007
    ..Overall, 1199 samples collected from 72 waterworks were analyzed. THMs, trichloroethylene and tetrachloroethylene were evaluated using the head-space gas chromatographic technique (detection limit of 0...
  87. ncbi De novo formation of chloroethyne in soil
    Frank Keppler
    Max Planck Institut for Nuclear Physics, Saupfercheckweg 1, 69117 Heidelberg, Germany
    Environ Sci Technol 40:130-4. 2006
    ..We therefore propose that the natural formation of chloroethyne in soil proceeds via oxidative cleavage of a quinonic system in the presence of the ubiquitous soil component chloride...
  88. ncbi Silicone emulsion-enhanced recovery of chlorinated solvents: batch and column studies
    Tae Soon Kwon
    Environmental Remediation Engineering Laboratory, Department of Chemical and Biomolecular Engineering, KAIST, 373 1 Guseong dong, Yuseong Gu, Daejeon 305 701, Republic of Korea
    J Hazard Mater 136:610-7. 2006
    ..The results of this study show that flushing with oil-based emulsion can be applied to treat the chlorinated solvents...
  89. ncbi Comparison between acetate and hydrogen as electron donors and implications for the reductive dehalogenation of PCE and TCE
    Il Su Lee
    Department of Environmental Engineering, Inha University, 253 Yonghyundong, Namgu, Inchon, South Korea
    J Contam Hydrol 94:76-85. 2007
    ..With the lower electron donor usage required, potential problems of aquifer clogging, excess methane production, and high groundwater chemical oxygen demand (COD) can be greatly reduced...
  90. ncbi Effectiveness of zerovalent iron and nickel catalysts for degrading chlorinated solvents and n-nitrosodimethylamine in natural groundwater
    Charles E Schaefer
    Shaw Environmental, Inc, 17 Princess Road, Lawrenceville, NJ 08648, USA
    Water Environ Res 79:57-62. 2007
    ....
  91. ncbi Perturbation of voltage-sensitive Ca2+ channel function by volatile organic solvents
    Timothy J Shafer
    Neurotoxicology Division, MD B105 05, NHEERL, ORD, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    J Pharmacol Exp Ther 315:1109-18. 2005
    ..These data demonstrate that VOCs perturb voltage-sensitive Ca2+ channel function in neurons, an effect that could contribute to the acute neurotoxicity of these compounds...
  92. ncbi Solvent release into a sandy aquifer 3: enhanced dissolution by methanol injection
    K Broholm
    Waterloo Centre for Groundwater Research, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada
    Environ Technol 28:11-8. 2007
    ..5 l of chloroform, 2.0 l of trichloroethylene, and 2.5 l of tetrachloroethylene) was carried out in a sandy, unconfined, shallow aquifer at Canadian Forces Base Borden, east of Toronto, ..
  93. ncbi Potential waste minimization of trichloroethylene and perchloroethylene via aerobic biodegradation
    Jian Wang
    Department of Civil Engineering, The University of Akron, Akron, Ohio 44325 3905, USA
    J Environ Sci Health A Tox Hazard Subst Environ Eng 40:1569-84. 2005
    ..03 d(-1)) was 2.2 times higher than without inducers (0.009 d(-1)). The addition of 0.2 microM phenol increased the rate constant by 58%. However, PCE degradation rates were not changed significantly...
  94. ncbi Assessing degradation rates of chlorinated ethylenes in column experiments with commercial iron materials used in permeable reactive barriers
    Markus Ebert
    Institute of Geosciences, Christian Albrechts Universitat zu Kiel, Ludewig Meyn Strasse 10, 24118 Kiel, Germany
    Environ Sci Technol 40:2004-10. 2006
    ....
  95. ncbi Toxicokinetics of inhaled trichloroethylene and tetrachloroethylene in humans at 1 ppm: empirical results and comparisons with previous studies
    Weihsueh A Chiu
    National Center for Environmental Assessment, U S Environmental Protection Agency, Washington, DC 20460, USA
    Toxicol Sci 95:23-36. 2007
    Trichloroethylene (TRI) and tetrachloroethylene (TETRA) are solvents that have been widely used in a variety of industries, and both are widespread environmental contaminants...
  96. ncbi Comparative evaluation of chloroethene dechlorination to ethene by Dehalococcoides-like microorganisms
    Alison M Cupples
    Department of Civil and Environmental Engineering, Stanford University, California 94305, USA
    Environ Sci Technol 38:4768-74. 2004
    ..Such ability to grow while dehalogenating TCE to ethene will be an important advantage for their use in bioaugmentation...
  97. ncbi Competition for sorption and degradation of chlorinated ethenes in batch zero-valent iron systems
    Jan Dries
    Department of Environmental Technology, Flemish Institute for Technological Research, Boeretang 200, 2400 Mol, Belgium
    Environ Sci Technol 38:2879-84. 2004
    ..The landfill groundwater with an organic carbon content of 109 mg L(-1) C had no effect on chloroethene sorption but inhibited TCE and PCE degradation by 60% and 70%, respectively...
  98. ncbi The distribution of the chlorinated solvents dichloromethane, perchloroethylene, and trichloroethylene in the global atmosphere
    Eduardo P Olaguer
    Environ Sci Pollut Res Int 9:175-82. 2002
    ..The simulated results suggest a greater importance for oceanic emissions of perchloroethylene and trichloroethylene than has previously been assumed...
  99. ncbi Carbon isotope fractionation during permanganate oxidation of chlorinated ethylenes (cDCE, TCE, PCE)
    Simon R Poulson
    Department of Geological Sciences, University of Nevada Reno, 89557 0138, USA
    Environ Sci Technol 36:3270-4. 2002
    ..Stable carbon isotope fractionation associated with permanganate oxidation of trichloroethylene (TCE), tetrachloroethylene (PCE), and cis-1,2-dichloroethylene (cDCE) has been measured, to study the possibility of applying stable ..
  100. ncbi Is neurotoxicity associated with environmental trichloroethylene (TCE)?
    Kaye H Kilburn
    University of Southern California, Keck School of Medicine, Environmental Sciences Laboratory, Los Angeles, California, USA
    Arch Environ Health 57:113-20. 2002
    ..An exposure zone was defined by concentrations of trichloroethylene, 1,1,1-trichloroethane, tetrachloroethylene, and vinyl chloride in groundwater...
  101. ncbi Anaerobic bioremediation of groundwater containing a mixture of 1,1,2,2-tetrachloroethane and chloroethenes
    Federico Aulenta
    Department of Chemistry, University of Rome La Sapienza, P le Aldo Moro 5, 00185, Rome, Italy
    Biodegradation 17:193-206. 2006
    ..No chloroethanes accumulated during degradation suggesting that 1,1,2,2-TeCA was degraded through initial dichloroelimination into DCEs and then typical hydrogenolysis into ETH and VC...

Research Grants16

  1. Receptor-based developmental and reproductive toxicity of Superfund chemicals
    David M Ozonoff; Fiscal Year: 2013
    ..abstract_text> ..
  2. Trichloroethylene and Parkinson's Disease
    Samuel M Goldman; Fiscal Year: 2013
    ..The chlorinated solvents tetrachloroethylene (PERC, perchloroethylene) and carbon tetrachloride (CCl4) were also associated...
  3. MECHANISM OF GLUTATHIONE CONJUGATE DEPENDENT TOXICITY
    Arthur Cooper; Fiscal Year: 2007
    ..g., trichloroethylene, tetrachloroethylene and tetrafluoroethylene) in the workplace and environment...
  4. CHEMICAL EFFECTS ON METABOLISM AND REPRODUCTION
    Mary Haasch; Fiscal Year: 2001
    ..are: clofibrate, as a model PPA, and haloxyfop enthoxyethyl, di-n-butyl-ortho-phthalate (DBoP) and tetrachloroethylene (PCE) as environmental contaminant PPAs...
  5. GLUTATHIONE AND MITOCHONDRIA IN TOXIC RENAL INJURY
    Lawrence Lash; Fiscal Year: 2003
    ..This information may have therapeutic applications for prevention of renal cellular injury or for understanding mitochondrial diseases or age-related decreases that occur in mitochondrial function. ..
  6. MOLECULAR TOXICOLOGY IN HUMAN KIDNEY CELLS
    Lawrence Lash; Fiscal Year: 2007
    ..Achievement of these aims should build on our previous work in human kidney cells and extend it to provide a much more complete understanding of the various and complex ways in which DCVC affects the human kidney [unreadable] [unreadable]..
  7. ASTHMA AND EXPOSURE TO PEAKS IN PARTICULATE AIR POLLUT
    RALPH DELFINO; Fiscal Year: 2001
    ..This research is expected to have an impact on decisions regarding the protection of health in populations frequently exposed to higher particle excursions. ..
  8. Pediatric Asthma, Particulate Air Pollution and NO2
    RALPH DELFINO; Fiscal Year: 2006
    ..Long-term goals are to improve knowledge about the independent and combined adverse effects of particulate and gaseous air pollutants by examining acute exposures and responses using ambulatory monitoring methods. ..
  9. COMMUNITY COMPOSITION AND PHYSIOLOGY OF ORAL BIOFILMS
    David White; Fiscal Year: 2001
    ..abstract_text> ..
  10. Wearable Organic Electric Film RFID Sensors for Monitoring of Airborne Toxicants
    Radislav A Potyrailo; Fiscal Year: 2010
    ..This new sensing approach will provide a wearable, cost-effective, selective sensor for de- tection of toxic volatile species. ..
  11. Three-generation Human Study of Reproductive Effects of Marine Food Contaminants
    PHILIPPE ADAM GRANDJEAN; Fiscal Year: 2010
    ..Current evidence already suggests that these pathologies may already affect many populations, and the present proposal aims at identifying whether persistent organochlorine pollutants contribute to these abnormalities. ..
  12. Health Effects of Lifetime Exposure to Food Contaminants
    Philippe Grandjean; Fiscal Year: 2009
    ..The results may therefore provide new information that could very likely have an impact on the preventive efforts and standard-setting of the EPA and other regulatory agencies in the U.S and elsewhere. ..
  13. Effects of perinatal endocrine disrupters in children
    Philippe Grandjean; Fiscal Year: 2004
    ..Modern statistical methods will be used to determine whether these outcome variables are associated with estrogen, thyroid, or Ah receptor abnormalities and specific contaminant exposures prenatally or postnatally. ..
  14. Metabolism of Carcinogens and Drugs by Human P450s
    F Guengerich; Fiscal Year: 2005
    ..Successful completion of these collective studies should provide better understanding of the ways in which human P450s catalyze oxidation of carcinogens and drugs and the significance of variations in these enzymes. ..
  15. A Temporal-Spatial Analysis of Breast Cancer in Upper C*
    Veronica Vieira; Fiscal Year: 2006
    ..By learning where breast cancer "hot spots" are and if they grow, intensify, or move over time, researchers will have a better understanding of how environmental risk factors may be involved. ..