octanes

Summary

Summary: Eight-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives.

Top Publications

  1. ncbi Ex situ treatment of hydrocarbon-contaminated soil using biosurfactants from Lactobacillus pentosus
    Ana Belén Moldes
    Chemical Engineering Department, University of Vigo, ETS Ingenieros Industriales, Campus As Lagoas, Marcosende, 36310 Vigo, Pontevedra, Spain
    J Agric Food Chem 59:9443-7. 2011
  2. ncbi Functional expression system for cytochrome P450 genes using the reductase domain of self-sufficient P450RhF from Rhodococcus sp. NCIMB 9784
    Miho Nodate
    Marine Biotechnology Institute, 3 75 1 Heita, Kamaishi, Iwate, 026 0001, Japan
    Appl Microbiol Biotechnol 71:455-62. 2006
  3. ncbi Comparison of two vectors for functional expression of a bacterial cytochrome P450 gene in Escherichia coli using CYP153 genes
    Naoya Fujita
    Marine Biotechnology Institute, Heita, Kamaishi, Japan
    Biosci Biotechnol Biochem 73:1825-30. 2009
  4. ncbi Production of alpha, omega-alkanediols using Escherichia coli expressing a cytochrome P450 from Acinetobacter sp. OC4
    Tadashi Fujii
    Bioresource Laboratories, Mercian Corporation, Shizuoka
    Biosci Biotechnol Biochem 70:1379-85. 2006
  5. ncbi Whole-cell hydroxylation of n-octane by Escherichia coli strains expressing the CYP153A6 operon
    Rama Krishna Gudiminchi
    Department of Microbial, Biochemical and Food Biotechnology, University of the Free State, P O Box 339, Bloemfontein 9300, South Africa
    Appl Microbiol Biotechnol 96:1507-16. 2012
  6. ncbi Enantioselective transesterification using lipase-displaying yeast whole-cell biocatalyst
    T Matsumoto
    Division of Molecular Science, Graduate School of Science and Technology, Kobe University, 1 1 Rokkodaicho, Nada Ku, 657 8501 Kobe, Japan
    Appl Microbiol Biotechnol 64:481-5. 2004
  7. pmc The molecular basis of electroporation
    D Peter Tieleman
    Department of Biological Sciences, University of Calgary, 2500 University Dr, NW, Calgary, Alberta T2N 1N4, Canada
    BMC Biochem 5:10. 2004
  8. pmc Nanosecond dynamics of a mimicked membrane-water interface observed by time-resolved stokes shift of LAURDAN
    Michel Vincent
    LURE Laboratoire pour l Utilisation du Rayonnement Electromagnétique, Universite Paris Sud, Batiment 209d, Orsay, France
    Biophys J 88:4337-50. 2005
  9. ncbi Effect of AOT on enzymatic activity of the organic solvent resistant tyrosinase from Streptomyces sp. REN-21 in aqueous solutions and water-in-oil microemulsions
    Janina Rodakiewicz-Nowak
    Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, 30 239 Krakow, Poland
    J Colloid Interface Sci 284:674-9. 2005
  10. ncbi Pressure-induced protein unfolding in the ternary system AOT-octane-water is different from that in bulk water
    Filip Meersman
    Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom
    Langmuir 21:3599-604. 2005

Detail Information

Publications190 found, 100 shown here

  1. ncbi Ex situ treatment of hydrocarbon-contaminated soil using biosurfactants from Lactobacillus pentosus
    Ana Belén Moldes
    Chemical Engineering Department, University of Vigo, ETS Ingenieros Industriales, Campus As Lagoas, Marcosende, 36310 Vigo, Pontevedra, Spain
    J Agric Food Chem 59:9443-7. 2011
    ..pentosus, as part of a well-designed bioremediation process, can provide mechanisms to mobilize the target contaminants from the soil surface to make them more available to the microbial population...
  2. ncbi Functional expression system for cytochrome P450 genes using the reductase domain of self-sufficient P450RhF from Rhodococcus sp. NCIMB 9784
    Miho Nodate
    Marine Biotechnology Institute, 3 75 1 Heita, Kamaishi, Iwate, 026 0001, Japan
    Appl Microbiol Biotechnol 71:455-62. 2006
    ..The system presented here may be applicable to the functional identification of a wide variety of bacterial cytochromes P450...
  3. ncbi Comparison of two vectors for functional expression of a bacterial cytochrome P450 gene in Escherichia coli using CYP153 genes
    Naoya Fujita
    Marine Biotechnology Institute, Heita, Kamaishi, Japan
    Biosci Biotechnol Biochem 73:1825-30. 2009
    ..It was also found that 2-n-butylbenzofuran is biotransformed into 4-benzofuran-2-yl-butyric acid via 4-benzofuran-2-yl-butan-1-ol with E. coli cells expressing CYP153A...
  4. ncbi Production of alpha, omega-alkanediols using Escherichia coli expressing a cytochrome P450 from Acinetobacter sp. OC4
    Tadashi Fujii
    Bioresource Laboratories, Mercian Corporation, Shizuoka
    Biosci Biotechnol Biochem 70:1379-85. 2006
    ..This is the first report on the bioproduction of alpha,omega-alkanediols from n-alkanes or 1-alkanols...
  5. ncbi Whole-cell hydroxylation of n-octane by Escherichia coli strains expressing the CYP153A6 operon
    Rama Krishna Gudiminchi
    Department of Microbial, Biochemical and Food Biotechnology, University of the Free State, P O Box 339, Bloemfontein 9300, South Africa
    Appl Microbiol Biotechnol 96:1507-16. 2012
    ..A maximum of 8.7 g octanol L (BRM)⁻¹ was obtained within 24 h (0.34 g L (BRM)⁻¹  h⁻¹) with IPTG-induced cells containing only 0.20 μmol P450 g (DCW)⁻¹, when glucose (22 g L (BRM)⁻¹) was added for cofactor regeneration...
  6. ncbi Enantioselective transesterification using lipase-displaying yeast whole-cell biocatalyst
    T Matsumoto
    Division of Molecular Science, Graduate School of Science and Technology, Kobe University, 1 1 Rokkodaicho, Nada Ku, 657 8501 Kobe, Japan
    Appl Microbiol Biotechnol 64:481-5. 2004
    ..The results obtained in this study demonstrate the applicability of the lipase-displaying yeast whole cell biocatalyst to bioconversion processes in non-aqueous organic solvents...
  7. pmc The molecular basis of electroporation
    D Peter Tieleman
    Department of Biological Sciences, University of Calgary, 2500 University Dr, NW, Calgary, Alberta T2N 1N4, Canada
    BMC Biochem 5:10. 2004
    ....
  8. pmc Nanosecond dynamics of a mimicked membrane-water interface observed by time-resolved stokes shift of LAURDAN
    Michel Vincent
    LURE Laboratoire pour l Utilisation du Rayonnement Electromagnétique, Universite Paris Sud, Batiment 209d, Orsay, France
    Biophys J 88:4337-50. 2005
    ..The measured relaxation time values were in the range of the rotational motion of the AOT polar headgroup region as assessed by LAURDAN and TOE fluorescence anisotropy decays...
  9. ncbi Effect of AOT on enzymatic activity of the organic solvent resistant tyrosinase from Streptomyces sp. REN-21 in aqueous solutions and water-in-oil microemulsions
    Janina Rodakiewicz-Nowak
    Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, 30 239 Krakow, Poland
    J Colloid Interface Sci 284:674-9. 2005
    ..12+/-0.02 and 0.051+/-0.006 for tBC and 4-MC, respectively), and the effective enzyme turnover number in the microemulsions remains practically constant...
  10. ncbi Pressure-induced protein unfolding in the ternary system AOT-octane-water is different from that in bulk water
    Filip Meersman
    Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom
    Langmuir 21:3599-604. 2005
    ..Our observations therefore suggest that membranes may cause the formation of alternative conformations that are more susceptible to aggregation...
  11. ncbi Influence of glymes upon percolative phenomena in AOT-based microemulsions
    J Dasilva-Carbalhal
    Departamento de Quimica Fisica, Facultade de Ciencias, Universidade de Vigo, 32004 Ourense, Spain
    J Colloid Interface Sci 292:591-4. 2005
    ..Such inclusion modifies the properties of the AOT film, facilitating the exchange of matter between droplets...
  12. ncbi Enzymatic redox cofactor regeneration in organic media: functionalization and application of glycerol dehydrogenase and soluble transhydrogenase in reverse micelles
    Hirofumi Ichinose
    Japan Science and Technology Agency, Precursory Research for Embryonic Science and Technology, 4 1 8, Honmachi, Kawaguchi, Saitama 332 0012, Japan
    Biotechnol Prog 21:1192-7. 2005
    ..These results indicate that GLD and STH have potential for use in redox cofactor recycling in reverse micelles, which allows the use of catalytic quantities of NAD(P)H in organic media...
  13. ncbi Phase behavior of the lecithin/water/isooctane and lecithin/water/decane systems
    Ruggero Angelico
    DISTAAM, Universita del Molise, v De Sanctis, 1 861 00 Campobasso, Italy
    Langmuir 20:619-31. 2004
    ..The use of the decane as oil does not change the main features of the phase behavior...
  14. ncbi Hydrolytic resolution of (R,S)-naproxen 2,2,2-trifluoroethyl thioester by Carica papaya lipase in water-saturated organic solvents
    I Son Ng
    Department of Chemical Engineering, National Cheng Kung University, Tainan, Taiwan 70101, Republic of China
    Biotechnol Bioeng 89:88-95. 2005
    ....
  15. ncbi Study of the factors affecting the forward and back extraction of yeast-lipase and its activity by reverse micelles
    Yan Chun Yu
    Department of Chemical Engineering, Huaihai Institute of Technology, Lanyungang 222005, People s Republic of China
    J Colloid Interface Sci 267:60-4. 2003
    ..One hundred percent of forward extraction yield, 68% of back extraction yield, and 45% of activity recovery yield for the lipase are obtained. The phase transfer of the lipase is controlled by electrostatic and hydrophobic interactions...
  16. ncbi Structural evolution of a two-component organogel
    Mohit Singh
    Department of Chemical and Biomolecular Engineering, Tulane University, New Orleans, Louisiana 70118, USA
    Langmuir 20:7392-8. 2004
    ..Upon a very small increment in the concentration of p-chlorophenol beyond this "threshold" concentration, large strandlike aggregates are observed which then evolve to the three-dimensional gel network...
  17. ncbi Bounded water kinetic model of beta-galactosidase in reverse micelles
    C Will Chen
    Department of Bioengineering, Tatung University, 40 Chungshan Road, 3rd Section, Taipei, Taiwan, Republic of China
    Bioprocess Biosyst Eng 26:307-13. 2004
    ..In contrast to the aqueous system, controlling the water concentration in the reverse micelles allows the rate constants for the reaction between water molecules and glycosyl-enzyme complexes to be evaluated...
  18. pmc Hydration of enzyme in nonaqueous media is consistent with solvent dependence of its activity
    Lu Yang
    Department of Chemical Engineering, Rensselaer Polytechnic Institute, Troy, New York 12180, USA
    Biophys J 87:812-21. 2004
    ....
  19. ncbi A novel method for the preparation of silver chloride nanoparticles starting from their solid powder using microemulsions
    Maen M Husein
    Department of Chemical Engineering, McGill University, Montreal, H3A 2B2, Canada
    J Colloid Interface Sci 288:457-67. 2005
    ..A monotonic decrease in the nanoparticle uptake accompanied by an increase in the particle size was observed when increasing n-decanol concentration or the water to surfactant mole ratio...
  20. ncbi Chiral recognition of zinc(II) ion complexes composed of bicyclo[3.3.0] octane-2,6-diol and s-naproxen probed by collisional-induced dissociation
    Chong Tian Yu
    Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, People s Republic of China
    J Am Soc Mass Spectrom 15:795-802. 2004
    ..Further discussion shows that steric interactions and pi-pi stacking interactions are the major factors responsible for the observed efficient chiral recognition in this system...
  21. ncbi Total synthesis of (+/-)-13-methoxy-15-oxozoapatlin, a rearranged kaurane diterpenoid
    Robert A Britton
    Department of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z1
    J Org Chem 69:3068-75. 2004
    ..Of particular note in this work is the development of a new method for the construction of the functionalized bicyclo[3.2.1]octane unit present in the target substance...
  22. ncbi The role of conformational flexibility of enzymes in the discrimination between amino acid and ester substrates for the subtilisin-catalyzed reaction in organic solvents
    Keiichi Watanabe
    Graduate School of Science and Technology, Kobe University, Nada 657 8501, Japan
    Bioorg Chem 32:504-15. 2004
    ..Our findings provide insight into the enantioselectivity enhancement for the resolution of enantiomers for enzyme-catalyzed reactions in organic solvents...
  23. ncbi Online kinetic studies on intermediates of laccase-catalyzed reaction in reversed micelle
    Zhi Hong Liu
    Department of Chemistry, Wuhan University, Wuhan 430072, China
    J Colloid Interface Sci 294:122-8. 2006
    ..The influences of microenvironmental factors of the medium (such as the pH value of the water pool and the water/AOT ratio) on the detection of the intermediate were also investigated...
  24. ncbi Cross-diffusion in a water-in-oil microemulsion loaded with malonic acid or ferroin. Taylor dispersion method for four-component systems
    Vladimir K Vanag
    Department of Chemistry and Volen Center for Complex Systems, MS 015, Brandeis University, Waltham, Massachusetts 02454, USA
    J Phys Chem B 112:9058-70. 2008
    ..The results should provide a basis for modeling pattern formation in the BZ-AOT system...
  25. ncbi Preparation and characterization of platinum-ruthenium bimetallic nanoparticles using reverse microemulsions for fuel cell catalyst
    Taeyoon Kim
    Advanced Research Center for Energy and Environment, Musashi Institute of Technology, Tokyo, Japan
    J Oleo Sci 56:553-62. 2007
    ....
  26. ncbi Preparation of coal slurry with organic solvents
    Yu Jen Shin
    Department of Resources Engineering, National Cheng Kung University, Tainan, Taiwan, ROC
    Chemosphere 68:389-93. 2007
    ..Thus, more surface area is available for combustion and the combustion rate of coal slurries was increased...
  27. ncbi Three-dimensional structure and dynamics of a de novo designed, amphiphilic, metallo-porphyrin-binding protein maquette at soft interfaces by molecular dynamics simulations
    Hongling Zou
    Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Phys Chem B 111:1823-33. 2007
    ..The simulation results are in qualitative agreement with available experimental data describing the structures at lower resolution and limited dimension...
  28. ncbi Formation of n-alkane layers at the vapor/water interface
    Oh Sun Kwon
    Department of Chemistry and Program of Integrated Biotechnology, Sogang University, Shinsoo, Mapogu, Seoul, Korea
    Langmuir 23:12249-53. 2007
    ..Our observations of continuous and saturated adsorption behaviors are analyzed qualitatively using a kinetic adsorption model...
  29. ncbi Switching electrical conductivity in an AOT-isooctane-water microemulsion through photodimerization of solubilized N-methyl-2-quinolone
    Markus Bufe
    Technische Universitat Dresden, Physikalische Chemie, Professur für Grenzflächen und Kolloidchemie, D 01062 Dresden, Germany
    Phys Chem Chem Phys 8:4222-7. 2006
    ..The effect can be reverted in part by irradiation at lambda = 250 nm. Coumarin derivatives--structurally related to NMQ--show much slighter effects...
  30. pmc Confinement or the nature of the interface? Dynamics of nanoscopic water
    David E Moilanen
    Department of Chemistry, Stanford University, Palo Alto, California 94305, USA
    J Am Chem Soc 129:14311-8. 2007
    ..The results demonstrate that confinement by an interface to form a nanoscopic water pool is a primary factor governing the dynamics of nanoscopic water rather than the presence of charged groups at the interface...
  31. ncbi Temperature-dependent solvation dynamics of water in sodium bis(2-ethylhexyl)sulfosuccinate/isooctane reverse micelles
    Rajib Kumar Mitra
    Unit for Nano Science and Technology, Department of Chemical, Biological, and Macromolecular Sciences, S N Bose National Center for Basic Sciences, Block JD, Sector III, Salt Lake, Kolkata, India
    Langmuir 24:49-56. 2008
    ..Time-resolved fluorescence anisotropy studies reveal a decrease in the rotational restriction on the probe with increasing temperature for all systems. Wobbling-in-cone analysis of the anisotropy data also supports this finding...
  32. ncbi Utility of 1-octanol/octane mixed solvents for the solvent extraction of aluminum(III), gallium(III), and indium(III) with 8-quinolinol
    Hiromichi Yamada
    Graduate School of Engineering, Shikumi College, Nagoya Institute of Technology, Gokisocho, Showa, Japan
    Anal Sci 22:371-6. 2006
    ....
  33. ncbi Oxovanadates: a novel probe for studying lipid-water interfaces
    Debbie C Crans
    Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA
    Biomed Pharmacother 60:174-81. 2006
    ..Furthermore, the vanadium-containing probe structure, charge and polarity can be modified for use in various biological settings. Here we introduce the concept and describe a few applications of this approach...
  34. ncbi Characterization of interaction between bergenin and human serum albumin in membrane mimetic environments
    Yaheng Zhang
    Department of Chemistry, Lanzhou University, Lanzhou, China
    J Fluoresc 18:661-70. 2008
    ..The DLS data suggested that HSA may locate at the interface of the microemulsion and bergenin could interact with them...
  35. ncbi Micelle-to-vesicle transition induced by organic additives in catanionic surfactant systems
    Haiqing Yin
    State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P R China
    Chemistry 12:2825-35. 2006
    ..Possible mechanisms for the above phenomena are presented, and the potential application of controllable micelle/vesicle systems in the synthesis of tailored bimodal mesoporous materials is discussed...
  36. ncbi Water dynamics--the effects of ions and nanoconfinement
    Sungnam Park
    Department of Chemistry Stanford University, Stanford, California 94305, USA
    J Phys Chem B 112:5279-90. 2008
    ....
  37. ncbi Rate-limited mass transfer of octane, decane, and dodecane into nonionic surfactants solutions under laminar flow conditions
    Dianne J Luning Prak
    US Naval Academy, 572M Holloway Road, Annapolis, MD 21402, USA
    Chemosphere 72:133-40. 2008
    ..Although these trends are specific for this experimental system, the results demonstrate the importance of selecting the proper diffusion coefficient when modeling surfactant solubilization processes...
  38. ncbi Oxidative refolding of reduced, denatured lysozyme in AOT reverse micelles
    Jun Bao Fan
    State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China
    J Colloid Interface Sci 322:95-103. 2008
    ..Together, our data demonstrate that AOT reverse micelles with suitable water-to-surfactant molar ratios are favorable to the oxidative refolding of reduced, denatured lysozyme at a higher concentration, compared with bulk water...
  39. ncbi Effect of alpha-lactalbumin on aerosol-OT phase structures in oil/water mixtures
    Jun Y Kim
    Department of Food Science and Technology, Department of Chemical Engineering and Materials Science, University of California, Davis, One Shields Avenue, Davis, California 95616, USA
    J Phys Chem B 112:5381-92. 2008
    ....
  40. ncbi Bicyclo[2.2.2]octene-based "crab-like" molecules: synthesis, complexation, luminescence properties, and solid-state structures
    Teh Chang Chou
    Department of Chemistry and Biochemistry, National Chung Cheng University, Minshong, Chiayi 621, Taiwan
    J Org Chem 70:9717-26. 2005
    ..The self-assembled intramolecular pi-stacking of pyrenyl rings in 25 with an interplanar distance of 3.40 A and the consequent pi-pi interactions were revealed by the X-ray crystal structure and its luminescence property...
  41. ncbi Dynamics of a membrane-bound tryptophan analog in environments of varying hydration: a fluorescence approach
    Amitabha Chattopadhyay
    Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India
    Eur Biophys J 35:62-71. 2005
    ..These results are relevant and potentially useful for analyzing dynamics of proteins or peptides bound to membranes or membrane-mimetic media under conditions of changing hydration...
  42. ncbi Improvement in extraction and catalytic activity of Mucor javanicus lipase by modification of AOT reverse micelle
    Mahabubur Rahman Talukder
    Institute of Chemical and Engineering Sciences, Singapore, Singapore
    Biotechnol J 2:1369-74. 2007
    ..The maximum specific activity of lipase extracted in PEG 400-modified reverse micellar system was threefold higher than that in the PEG-free system...
  43. ncbi Synthesis of highly functionalised enantiopure bicyclo[3.2.1]- octane systems from carvone
    Antonio Abad
    Departamento de Quimica Organica, Facultad de Ciencias Quimicas, Dr Moliner, 50, 46100 Burjasot, Valencia, Spain
    Molecules 9:287-99. 2004
    ..The sequence used for this transformation involves as key features an intramolecular Diels-Alder reaction of a 5-vinyl-1,3-cyclohexadiene and a cyclopropane ring opening...
  44. ncbi [Stability of glucose 6-phosphate dehydrogenase complexed with its substrate and/or cofactor in aqueous and micellar environment]
    A V Puchkaev
    Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, 5 2 Kuprevich St, Minsk, 220141 Belarus
    Prikl Biokhim Mikrobiol 38:44-52. 2002
    ..In addition, this approach demonstrated that G6PDH undergoes destabilization in AOT micelles...
  45. ncbi Kinetic method for determining antioxidant distributions in model food emulsions: distribution constants of t-butylhydroquinone in mixtures of octane, water, and a nonionic emulsifier
    Laurence S Romsted
    Center for Advanced Food Technology and Department of Chemistry and Chemical Biology, Wright and Rieman Laboratories, Rutgers, The State University of New Jersey, New Brunswick, New Jersey 08903, USA
    J Agric Food Chem 50:3328-36. 2002
    ..About 90% of the TBHQ is in the surfactant film at about 2% volume fraction of C(12)E(6), which suggests that this region may be the primary site of antioxidant activity for neutral phenolic antioxidants...
  46. ncbi Characterization of patatin esterase activity in AOT-isooctane reverse micelles
    M Jimenez
    Departamento de Bioquimica y Biologia Molecular A, Universidad de Murcia, Espinardo 30071, Murcia, Spain
    Biotechnol Prog 18:635-40. 2002
    ..8 x 10(-3) min(-1)). This paper shows the suitability of reverse micelles for measuring patatin esterase activity, since it allows the study of the enzyme in similar conditions to that prevailing in vivo...
  47. ncbi Rearrangement of a mesylate tropane intermediate in nucleophilic substitution reactions. Synthesis of aza-bicyclo[3.2.1]octane and aza-bicyclo[3.2.2]nonane ethers, imides, and amines
    Lionel Ogier
    Department of Psychiatry, Yale University and VA CT HCS, West Haven, Connecticut, USA
    J Org Chem 67:3637-42. 2002
    ..2.2]nonane structure was obtained, whereas the use of amines or imides as nucleophile afforded a mixture of the two structures. The bicyclo[3.2.2]nonane structure was assigned by NMR analysis...
  48. ncbi A new route to (+)-estrone using a bicyclo[3.2.1]octane chiral building block
    Keisuke Hanada
    Pharmaceutical Institute, Tohoku University, Sendai, Japan
    Chem Pharm Bull (Tokyo) 51:104-6. 2003
    ..A new route to (+)-estrone has been developed starting from the chiral building block having a bicyclo[3.2.1]octane framework based on the inherent stereochemical chemical nature of the chiral building block...
  49. ncbi Determination of phenol using an enhanced chemiluminescent assay
    A D Ilyina
    Departamento de Biotecnologia, Facultad de Ciencias Químicas de la Universidad Autónoma de Coahuila, República, AP 935, CP 25000, Saltillo, Coahuila, Mexico
    Luminescence 18:31-6. 2003
    ..006, 0.003 and 0.0005 mg/mL, respectively, for the buffer-containing system, the AOT-applied system with phenol standard solutions in water and for the AOT-applied system with phenol standard solutions in octane...
  50. ncbi Indigo production by Escherichia coli carrying the phenol hydroxylase gene from Acinetobacter sp strain ST-550 in a water-organic solvent two-phase system
    N Doukyu
    Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Nagatsuta 4259, Midori ku, Yokohama 226 8501, Japan
    Appl Microbiol Biotechnol 60:720-5. 2003
    ..The OST3410 recombinant produced 52 microg indigo ml(-1) of medium in the presence of diphenylmethane. This productivity was 4.3-fold higher than that of the JA300 recombinant...
  51. ncbi Synthesis of bicyclic amines and their activities against Trypanosoma brucei rhodesiense and Plasmodium falciparum K1
    Robert Weis
    Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, Karl Franzens University, Universitatsplatz 1, A 8010, Graz, Austria
    Arch Pharm Res 31:688-97. 2008
    ..2.2.0(2,4)]nonylamines exhibit similar antiprotozoal activities as 4-aminobicyclo[2.2.2] octanes. 4-Aminobicyclo[2.2...
  52. ncbi Synthetic approaches to the polycyclic alkaloid stemofoline
    Alison M Baylis
    The School of Chemistry, The University of Manchester, Manchester, UK
    Org Biomol Chem 5:3139-55. 2007
    ..The analogous ketones 15, 18, and 19 were also cyclised to give the 8-azabicyclo[3.2.1]octanes 22-24 with axial electron-withdrawing 2-substituents...
  53. ncbi Distance indices and their hyper-counterparts: intercorrelation and use in the structure-property modeling
    N Trinajstic
    Rugjer Boskovic Institute, P O Box 180, HR 10002 Zagreb, Croatia
    SAR QSAR Environ Res 12:31-54. 2001
    ..the second set (S-139) 139 cyclic hydrocarbons from cyclopropane to branched and unbranched polycyclic octanes and the third set (S-178) is a combination of the first two sets (178 molecules)...
  54. ncbi Diversity-oriented synthesis of azaspirocycles
    Peter Wipf
    Department of Chemistry, Center for Chemical Methodologies and Library Development, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Org Lett 6:3009-12. 2004
    ..These novel building blocks are converted into heterocyclic 5-azaspiro[2.4]heptanes, 5-azaspiro-[2.5]octanes, and 5-azaspiro[2...
  55. ncbi Synthesis of 6- and 7- hydroxy-8-azabicyclo[3.2.1]octanes and their binding affinity for the dopamine and serotonin transporters
    P C Meltzer
    Organix Inc, 240 Salem Street, Woburn, Massachusetts 01801, USA
    J Med Chem 44:2619-35. 2001
    ..This study extends the exploration of bridge hydroxylated azabicyclo[3.2.1]octanes (tropanes). A series of 6- and 7-hydroxylated tropanes was prepared and evaluated biologically...
  56. ncbi Synthesis of 2-azabicyclo[3.2.2]nonanes from bicyclo[2.2.2]octan-2-ones and their activities against Trypanosoma brucei rhodesiense and Plasmodium falciparum K1
    Werner Seebacher
    Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, Karl Franzens University, A 8010 Graz, Austria
    J Pharm Pharm Sci 8:578-85. 2005
    ..2.2]octan-2-ones to investigate the influence of the replacement of the rigid bicyclo-octane structure by the more flexible bicyclo-nonane system on the antiplasmodial and antitrypanosomal activity...
  57. ncbi Selectfluor as a nucleofuge in the reactions of azabicyclo[n.2.1]alkane beta-halocarbamic acid esters (n = 2,3)
    Grant R Krow
    Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, USA
    J Org Chem 73:2122-9. 2008
    ..2.1]heptanes and 4-anti-Y-8-anti-X-6-azabicyclo[3.2.1]octanes. The azabicycles contained X = I or Br groups in the methano bridge and Y = F, Br, Cl, or OH substituents in the ..
  58. ncbi Conversion of the iridoid glucoside antirrhinoside into 3-azabicyclo[3.3.0]octane building blocks
    H Franzyk
    Department of Organic Chemistry, The Technical University of Denmark, Building 201, DK 2800, Lyngby, Denmark
    J Nat Prod 63:592-5. 2000
    The iridoid glucoside antirrhinoside (1) was transformed into polysubstituted 3-azabicyclo[3.3.0]octanes 3, 12, and 13 in 4 to 5 steps...
  59. pmc Stereocontrolled synthesis and pharmacological evaluation of cis-2,6-diphenethyl-1-azabicyclo[2.2.2]octanes as lobelane analogues
    Guangrong Zheng
    College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536 0082, USA
    J Org Chem 74:6072-6. 2009
    ....
  60. ncbi 2-Carbomethoxy-3-aryl-8-bicyclo[3.2.1]octanes: potent non-nitrogen inhibitors of monoamine transporters
    P C Meltzer
    Organix Inc, 240 Salem Street, Woburn, Massachusetts 01801, USA
    J Med Chem 43:2982-91. 2000
    ..2.1]octanes yields potent inhibitors of monoamine transport...
  61. pmc The synthesis and biological evaluation of 2-(3-methyl or 3-phenylisoxazol-5-yl)-3-aryl-8-thiabicyclo[3.2.1]octanes
    Madhusudhan Purushotham
    Organix Inc, 240 Salem Street, Woburn, MA 01801, USA
    Bioorg Med Chem Lett 21:48-51. 2011
    ..We had reported that 3-aryl-2-carbomethoxy-8-thiabicyclo[3.2.1]octanes are potent and selective inhibitors of the DAT...
  62. ncbi 2,7-diazabicyclo[3.3.0]octanes as novel h5-HT receptor agonists
    M G Russell
    Merck Sharp and Dohme Research Laboratories, Neuroscience Research Centre, Harlow, Essex, UK
    Bioorg Med Chem Lett 9:2491-6. 1999
    The conformational restriction of a (benzylamino)methyl substituted pyrrolidine to form 2,7-diazabicyclo[3.3.0]octanes has led to a series of compounds with high affinity at the h5-HT1D receptor as well as dramatically increased ..
  63. ncbi Nitrogen-based drugs are not essential for blockade of monoamine transporters
    B K Madras
    Department of Psychiatry, Harvard Medical School, NERPRC, Southborough, MA 01772 9102, USA
    Synapse 24:340-8. 1996
    ..We report that several compounds without nitrogen (8-oxa-bicyclo-3-aryl-[3.2.1] octanes, or aryloxatropanes) are active at monoamine transporters...
  64. ncbi Synthesis and antiproliferative properties of N3/8-disubstituted 3,8-diazabicyclo[3.2.1]octane analogues of 3,8-bis[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl-piperazine
    Rosanna Filosa
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte Don Melillo, 84084 Fisciano SA, Italy
    Eur J Med Chem 42:293-306. 2007
    A series of novel N(3/8)-disubstituted-3,8-diazabicyclo[3.2.1]octanes in order to improve the in vitro activity of the prototype 3,8-bis[2-(3,4,5-trimethoxyphenyl)pyridyl-4-yl)methylpiperazine (1) were synthesized and evaluated by assays ..
  65. pmc Bicyclo[2.2.2]octanes: close structural mimics of the nuclear receptor-binding motif of steroid receptor coactivators
    Hai Bing Zhou
    Department of Chemistry, University of Illinois, 600 South Mathews Avenue, Urbana, IL 61801, USA
    Bioorg Med Chem Lett 17:4118-22. 2007
    ..We have synthesized a series of bicyclo[2.2.2]octanes that are close structural mimics of the two key leucine residues of this SRC sequence as bound in the hydrophobic ..
  66. ncbi Diels-Alder cycloaddition and ring-closing metathesis: a versatile, stereoselective, and general route to embellished bridged bicyclic systems, carbocyclic framework of secoatisanes, and homologues
    Vishwakarma Singh
    Department of Chemistry, Indian Institute of Technology, Bombay, Mumbai 400 076, India
    J Org Chem 74:6092-104. 2009
    ..2.2]octanes having an allyl group at the bridgehead and other chemically distinguishable functionality in a regio- and ..
  67. ncbi A versatile access to calystegine analogues as potential glycosidases inhibitors
    Krishna P Kaliappan
    Department of Chemistry, Indian Institute of Technology Bombay, Mumbai 400 076, India
    J Org Chem 74:6266-74. 2009
    An efficient metathetic strategy and nitrone chemistry have been suitably tethered to construct 8-azabicyclo[3.2.1]octanes as versatile precursors for the synthesis of several calystegine analogues...
  68. ncbi Synthetic and computational studies on the tricarboxylate core of 6,7-dideoxysqualestatin H5 involving a carbonyl ylide cycloaddition-rearrangement
    David M Hodgson
    Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, UK OX1 3TA
    Org Biomol Chem 8:3975-84. 2010
    ..2.1]octanes 29 and 30, respectively...
  69. ncbi Asymmetric organocatalytic domino Michael/aldol reactions: enantioselective synthesis of chiral cycloheptanones, tetrahydrochromenones, and polyfunctionalized bicyclo[3.2.1]octanes
    Magnus Rueping
    Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52056 Aachen, Germany
    Angew Chem Int Ed Engl 48:3699-702. 2009
    ..Additionally, a retro-aldol cyclization provides access to valuable tetrahydrochromenones (see scheme)...
  70. ncbi Dialkylaminoalkyl derivatives of bicyclic compounds with antiplasmodial activity
    Johanna Faist
    Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Universitatsplatz 1, A 8010 Graz, Austria
    Bioorg Med Chem 18:6796-804. 2010
    Dialkylaminoalkyl derivatives of 2-azabicyclo[3.2.2]nonanes and of bicyclo[2.2.2]octanes were prepared and their activities determined in vitro against the multiresistant K1 strain of Plasmodium falciparum...
  71. ncbi Neighboring group participation in the additions of iodonium and bromonium ions to N-alkoxycarbonyl-2-azabicyclo[2.2.n]alk-5-enes (n = 1,2)
    Grant R Krow
    Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, USA
    J Org Chem 73:2114-21. 2008
    ..2.2]octanes were formed by nucleophilic attack at C(5) on syn-halonium ions...
  72. ncbi Synthesis and monoamine transporter affinity of 3beta-(4-(2-pyrrolyl)phenyl)-8-azabicycl
    H M Davies
    Department of Chemistry, State University of New York at Buffalo, 14260 3000, USA
    Bioorg Med Chem Lett 11:487-9. 2001
    3Beta-(5-indolyl)-8-azabicyclo[3.2.1]octanes display potent binding affinity for both the dopamine and serotonin transporters, while certain 3beta-(4-(2-pyrrolyl)phenyl)-8-azabicyclo[3.2...
  73. ncbi Evaluation of a 4-aminopiperidine replacement in several series of CCR5 antagonists
    Rémy C Lemoine
    Department of Medicinal Chemistry, Roche Palo Alto, Palo Alto, CA 94304, USA
    Bioorg Med Chem Lett 20:1830-3. 2010
    The bicyclic 5-amino-3-azabicyclo[3.3.0]octanes were shown to be effective replacements for the conformationally restricted 4-aminopiperidine ring found in several series of CCR5 antagonists.
  74. ncbi Evaluation of a 3-amino-8-azabicyclo[3.2.1]octane replacement in the CCR5 antagonist maraviroc
    Rémy C Lemoine
    Department of Medicinal Chemistry, Roche Palo Alto, 3431 Hillview Avenue, Palo Alto, CA 94304, USA
    Bioorg Med Chem Lett 20:1674-6. 2010
    The bicyclic 5-amino-3-azabicyclo[3.3.0]octanes were shown to be effective replacements for the 3-amino-8-azabicyclo[3.2.1]octane found in the CCR5 antagonist maraviroc.
  75. ncbi Characterization of pyridine-octanethiolated gold nanoparticles: desorption kinetics by thermal analysis mass spectrometry
    Teng Yuan Dong
    Department of Chemistry, Center for Nanoscience and Nanotechnology, National Sun Yat Sen University, Kaohsiung, Taiwan
    J Nanosci Nanotechnol 7:3268-76. 2007
    ..The TA-mass spectra have revealed that MCPs exist monomer and dimer desorption behavior from monomeric thiolate adsorbed on the surface...
  76. pmc The tension of a curved surface from simulation
    Alexander J Sodt
    National Heart, Lung, and Blood Institute, National Institutes of Health, 50 South Drive, Bethesda, Maryland 20892, USA
    J Chem Phys 137:234101. 2012
    ..7 dyn/cm). Finally, an ambiguity is resolved between the Harasima and Irving-Kirkwood methods of calculating the local pressure as a means for computing the tension...
  77. pmc On the structure of palau'amine: evidence for the revised relative configuration from chemical synthesis
    Brian A Lanman
    Department of Chemistry, 1102 Natural Sciences II, University of California, Irvine, CA 92697 2025, USA
    J Am Chem Soc 129:12896-900. 2007
    ..3.0]octane ring system of palau'amine and congeners...
  78. ncbi Locked nucleosides based on oxabicyclo[3.2.1]octane and oxabicyclo[2.2.1]heptane skeletons
    Ramprasad Ghosh
    Department of Chemistry, Indian Institute of Chemical Biology A unit of CSIR, 4, Raja S C Mullick Road, Jadavpur, Kolkata 700 032, India
    J Org Chem 75:2419-22. 2010
    ..Participation of a neighboring benzyl ether substituent in one case paved the way for an enantiodivergent synthesis...
  79. ncbi [A method of determining global migration from plastic packing materials into model fluids simulating food products containing fat according to directives of the EWG Commission]
    I Lewandowska
    , Warszawa
    Rocz Panstw Zakl Hig 47:415-21. 1996
    ..It should be introduced promptly for routine control of packing materials in the laboratories of the Province Sanitary-Epidemiological Stations...
  80. ncbi Intramolecular hydrogen abstraction reaction promoted by N-radicals in carbohydrates. Synthesis of chiral 7-oxa-2-azabicyclo[2.2.1]heptane and 8-oxa-6-azabicyclo[3.2.1]octane ring systems
    Cosme G Francisco
    Instituto de Productos Naturales y Agrobiología del C S I C, Carretera de La Esperanza 3, 38206 La Laguna, Tenerife, Spain
    J Org Chem 68:1012-7. 2003
    ....
  81. ncbi Aqueous solubility, Henry's law constants and air/water partition coefficients of n-octane and two halogenated octanes
    S Sarraute
    Laboratoire de Thermodynamique des Solutions et des Polymeres, UMR 6003, CNRS Univ Blaise Pascal, 24, avenue des Landais, 63177 Aubiere Cedex, France
    Chemosphere 57:1543-51. 2004
    ..A thorough thermodynamic analysis of converting measured data to air/water partition coefficients is presented...
  82. ncbi Reverse micellar extraction systems for the purification of pharmaceutical grade plasmid DNA
    Nadine Streitner
    Faculty of Technology, Bielefeld University, PO 100 131, D 33501 Bielefeld, Germany
    J Biotechnol 131:188-96. 2007
    ..The capability of reverse micellar systems for plasmid form separation was also shown by capillary and agarose gel electrophoresis...
  83. ncbi Distinguishing octane grades in gasoline using terahertz metamaterials
    J Li
    State Key Laboratory of Precision Measuring Technology and Instruments, Tianjin University, Tianjin 300072, China
    Appl Opt 51:3258-62. 2012
    ..This paper reveals that such metamaterial arrays, as highly sensitive chemical sensors, have promising potential in petroleum industrial applications...
  84. ncbi [The lipase/lipoxygenase bienzyme system in AOT reversed micelles in octane]
    I M Pavlenko
    Moscow State University, Chemical Faculty, Vorob evy Gory, GSP 3 Moscow, 119899 Russia
    Bioorg Khim 28:50-5. 2002
    ..The lipase/lipoxygenase bienzyme system can be used as a new method of spectrophotometric determination of lipase activity. The English version of the paper...
  85. ncbi Catalytic activity of lignin peroxidase and partition of veratryl alcohol in AOT/isooctane/toluene/water reverse micelles
    Wenjuan Zhang
    Key Lab for Colloid and Interface Chemistry of the Education Ministry of China, Shandong University, Jinan, 250100, People s Republic of China
    Appl Microbiol Biotechnol 70:315-20. 2006
    ..The differences mentioned above should be ascribed to the microheterogeneity and the interface of the AOT reverse micelle...
  86. pmc Further structure-activity relationship studies on 8-substituted-3-[2-(diarylmethoxyethylidenyl)]-8-azabicyclo[3.2.1]octane derivatives at monoamine transporters
    SHAINE A CARARAS
    Department of Chemistry, University of New Orleans, New Orleans, 2000 Lakeshore Drive, LA 70148, USA
    Bioorg Med Chem 19:7551-8. 2011
    ..Similarly, the 8-chlorobenzyl derivative 22g (DAT K(i) of 3.9 nM) was found to be highly selective for the DAT over the NET (NET/DAT: 1358)...
  87. ncbi Neutral homoaromaticity in some heterocyclic systems
    Peter K Freeman
    Department of Chemistry, Oregon State University, Corvallis, Oregon 97331, USA
    J Org Chem 70:1998-2001. 2005
    ....
  88. ncbi Contribution to linearly programmed temperature gas chromatography. Further application of the Van den Dool-Kratz equation, and a new utilization of the Sadtler retention index library
    José M Santiuste
    Instituto de Quimica Fisica Rocasolano, CSIC, Department of Structure and Molecular Dynamics, C Serrano 119, 28006 Madrid, Spain
    J Chromatogr A 1181:103-15. 2008
    ..Based on an earlier "equivalent" temperature concept and on Tekler's proviso, a novel way for the utilization of Sadtler's retention index database, which takes advantage of the 3 data supplied by the library, is proposed...
  89. ncbi Vortex-assisted liquid-liquid microextraction coupled with derivatization for the fluorometric determination of aliphatic amines
    Wei Yao Chang
    Environmental Chemistry Laboratory, Department of Biomedical Engineering and Environmental Sciences, College of Nuclear Science, National Tsing Hua University, Hsinchu 30013, Taiwan
    J Chromatogr A 1248:41-7. 2012
    ..4 and 40 nM. The proposed method has been applied to the determination of aliphatic amines in acidophilus milk, beer, and Cu(II)/amino acid solution...
  90. ncbi Catalytic dehydroaromatization of n-alkanes by pincer-ligated iridium complexes
    Ritu Ahuja
    Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854, USA
    Nat Chem 3:167-71. 2011
    ..In the case of n-decane and n-dodecane, the resulting alkylarenes are exclusively unbranched (that is, n-alkyl-substituted), with selectivity for the corresponding o-(n-alkyl)toluene...
  91. ncbi Stability and comparative analysis of AOT/water/isooctane reverse micelle system using dynamic light scattering and molecular dynamics
    V R Vasquez
    Chemical and Materials Engineering, University of Nevada, Reno, Reno, Nevada 89557, USA
    J Phys Chem B 115:2979-87. 2011
    ..These type of salts are common for reverse micellar synthesis processes. We find that zirconyl chloride affects significantly the size distributions...
  92. ncbi Switchable pickering emulsions stabilized by silica nanoparticles hydrophobized in situ with a switchable surfactant
    Jianzhong Jiang
    The Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122 P R China
    Angew Chem Int Ed Engl 52:12373-6. 2013
    ..Switchable oil-in-water Pickering emulsions that entail a CO2 /N2 trigger were obtained by using negatively charged silica nanoparticles and a trace amount of the switchable surfactant as the stabilizer. ..
  93. ncbi Comparison of microemulsion electrokinetic chromatography with high-performance liquid chromatography for fingerprint analysis of resina draconis
    Yuhua Cao
    School of Chemical and Material Engineering, Jiangnan University, Wuxi, 214122, China
    Anal Bioanal Chem 392:1003-10. 2008
    ..So, MEEKC was more suitable for development of the fingerprint of resina draconis...
  94. ncbi An unusual Michael-induced skeletal rearrangement of a bicyclo[3.3.1]nonane framework of phloroglucinols to a novel bioactive bicyclo[3.3.0]octane
    Veroniki P Vidali
    Synthesis and Bioorganic Chemistry, NCSR Demokritos, 153 10 Ag Paraskevi, Athens, Greece, Chemical Laboratories, Agricultural University of Athens, Iera Odos 75, 118 55, Athens, Greece, Crystal Engineering, Growth and Design Laboratory, Department of Chemistry, University of Crete, P O Box 2208, GR 71003 Heraklion, Crete, Greece, EPOS Iasis, R and D, 5 Karyatidon Street, 2028, Nicosia, Cyprus, and University of Cyprus, 75 Kallipoleos Avenue, 1678 Nicosia, Cyprus
    Org Lett 15:5404-7. 2013
    ..A mechanistic study was examined in detail, proposing a number of cascade transformations. Also, reactivity of the Δ(7,10)-double bond was examined under several conditions to explain the above results. ..
  95. ncbi Insertions of silylenes into vinyl epoxides: diastereoselective synthesis of functionalized, optically active trans-dioxasilacyclooctenes
    Michel Prévost
    Department of Chemistry, University of California, Irvine, California 92697 2025, USA
    J Am Chem Soc 131:14182-3. 2009
    ..Diastereoselective additions to these alkenes allow efficient transfer of planar chirality to chirality at stereogenic carbon atoms...
  96. ncbi Synthesis and biological evaluation of a novel 3-sulfonyl-8-azabicyclo[3.2.1]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors
    Tsuyoshi Nagase
    Tsukuba Research Institute, Merck Research Laboratories, Banyu Pharmaceutical Co, Ltd, Tsukuba, Ibaraki 300 2611, Japan
    J Med Chem 52:4111-4. 2009
    ..2.1]octane class of ELOVL6 inhibitor 1a. Optimization of lead 1a led to the identification of the potent, selective, and orally available ELOVL6 inhibitor 1w...
  97. ncbi AFM-based nanotribological and electrical characterization of ultrathin wear-resistant ionic liquid films
    Bharat Bhushan
    Nanotribology Laboratory for Information Storage and MEMS NEMS NLIM, The Ohio State University, 201 W 19th Ave, Columbus, OH 43210, USA
    J Colloid Interface Sci 317:275-87. 2008
    ..e., partially bonded) were better able to protect the Si substrate from wear compared to the fully bonded coatings, and this enhanced protection is attributed to lubricant replenishment...
  98. ncbi Protective group-free syntheses of (±)-frontalin, (±)-endo-brevicomin, (±)-exo-brevicomin, and (±)-3,4-dehydro-exo-brevicomin: racemic pheromones with a 6,8-dioxabicyclo[3.2.1]octane ring
    Kenji Mori
    Photosensitive Materials Research Center, Toyo Gosei Co, Ltd, Chiba, Japan
    Biosci Biotechnol Biochem 75:976-81. 2011
    ....
  99. ncbi Oxidative dearomatization/intramolecular Diels-Alder cycloaddition cascade for the syntheses of (±)-atisine and (±)-isoazitine
    Xiao yu Liu
    Department of Chemistry of Medicinal Natural Products, Sichuan University, No 17, Duan 3, Renmin Nan Road, Chengdu, 610041
    Org Biomol Chem 10:1411-7. 2012
    ..The first total synthesis of another atisine-type C(20)-diterpenoid alkaloid, (±)-isoazitine, has also been achieved employing the same strategy...
  100. ncbi Stereodivergence in amine-catalyzed regioselective [4 + 2] cycloadditions of β-substituted cyclic enones and polyconjugated malononitriles
    Xin Feng
    Key Laboratory of Drug Targeting and Drug Delivery System of the Ministry of Education, West China School of Pharmacy, West China Hospital, Sichuan University, Chengdu 610041, China
    J Am Chem Soc 134:19942-7. 2012
    ..2.2]octanes or analogous architectures with moderate to excellent diastereo- and enantioselectivity by the catalysis of ..
  101. ncbi TADH, the thermostable alcohol dehydrogenase from Thermus sp. ATN1: a versatile new biocatalyst for organic synthesis
    Volker Höllrigl
    Laboratory of Chemical Biotechnology, Department of Biochemical and Chemical Engineering, TU Dortmund, Emil Figge Strasse 66, 44227, Dortmund, Germany
    Appl Microbiol Biotechnol 81:263-73. 2008
    ..When applying cofactor regeneration at high pH, however, the ratio of acid to alcohol could be changed, and full conversion to the carboxylic acid was achieved...

Research Grants10

  1. REACTIVITY AND SELECTIVITY OF REACTIONS IN POLAR MEDIA
    PAUL GRIECO; Fiscal Year: 2002
    ..2.1]heptanes and oxabicyclo [3.2.1]octanes i highly polar media...
  2. Discovery of Novel Pharmacotherapies: Cocaine Dependence
    PETER MELTZER; Fiscal Year: 2008
    ..We will focus on three classes: 8-oxabicyclo[3,2,1]octanes (oxatropanes), 8-azabicyclo[3,2,1]octanes (tropanes) and pyrovalerone analogues...
  3. INTERESTING BIOACTIVE SUBSTANCES
    David Williams; Fiscal Year: 2006
    ..The selective synthesis of contiguous stereotriads will advance basic methodology for asymmetric conjugate additions. ..
  4. CHEMICAL SYNTHESIS OF NOVEL NATURAL PRODUCTS
    David Williams; Fiscal Year: 2009
    ..Daphnicyclidin A. This recent discovery has revealed a new molecular architecture which exhibits significant antitumor activity. Our research will investigate strategies for chemical synthesis of these complex polycyclic systems. ..
  5. SYNTHESIS OF ANTITUMOR AGENTS AND RELATED CHEMISTRY
    Steven Burke; Fiscal Year: 2004
    ..2. To further develop a powerful synthesis of 6,8-dioxabicyclo(3.2.1)octanes by intermolecular acetalization/intramolecular diene metathesis, for application to sialic acid syntheses (KDN, N-..
  6. NATURAL PRODUCT SYNTHESIS THROUGH TEMPLATE DIRECTED C-H
    DUNCAN WARDROP; Fiscal Year: 2003
    ..abstract_text> ..
  7. Expeditious Synthesis of Complexity and Diversity
    Steven Burke; Fiscal Year: 2007
    ....
  8. Synthesis through N-Acylnitrenium Ion Cyclization
    DUNCAN WARDROP; Fiscal Year: 2006
    ..abstract_text> ..
  9. Strategies for Efficient Routes to Bioactive Substances
    Steven Burke; Fiscal Year: 2006
    ..The proposed syntheses are one-third to one-half as long as comparative benchmarks for these targets, illustrating the effectiveness of this developing strategy for dramatically affecting synthetic efficiency. ..
  10. CHEMISTRY AND BIOLOGY OF INSULIN-LIKE VANADIUM COMPOUNDS
    DEBBIE CRANS; Fiscal Year: 2003
    ..The proposed studies will lead to an in-depth understanding of both the chemical and pharmacological properties of known and new vanadium compounds inducing insulin-like action. ..