formates

Summary

Top Publications

  1. ncbi Efficient hydrogenation of organic carbonates, carbamates and formates indicates alternative routes to methanol based on CO2 and CO
    Ekambaram Balaraman
    Department of Organic Chemistry, The Weizmann Institute of Science, Rehovot, 76100, Israel
    Nat Chem 3:609-14. 2011
  2. pmc Formate as the main branch point for methylotrophic metabolism in Methylobacterium extorquens AM1
    Gregory J Crowther
    Department of Chemical Engineering, University of Washington, Box 355014, Seattle, Washington 98195 5014, USA
    J Bacteriol 190:5057-62. 2008
  3. ncbi The molecular biology of formate metabolism in enterobacteria
    Susanne Leonhartsberger
    Institute of Genetics and Microbiology, University of Munich
    J Mol Microbiol Biotechnol 4:269-76. 2002
  4. ncbi Development of an insertional expression vector system for Methylobacterium extorquens AM1 and generation of null mutants lacking mtdA and/or fch
    Christopher J Marx
    Department of Microbiology, University of Washington, Seattle, WA 98195, USA
    Microbiology 150:9-19. 2004
  5. ncbi Elevated formic acid concentrations in putrefied post-mortem blood and urine samples
    Jenni Viinamäki
    Hjelt Institute, Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
    Forensic Sci Int 208:42-6. 2011
  6. ncbi Methanol toxicity and formate oxidation in NEUT2 mice
    R J Cook
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 0146, USA
    Arch Biochem Biophys 393:192-8. 2001
  7. ncbi Methanol, formaldehyde, and sodium formate exposure in rat and mouse conceptuses: a potential role of the visceral yolk sac in embryotoxicity
    Jason M Hansen
    Department of Biochemistry, School of Medicine, Emory University, Atlanta, Georgia, USA
    Birth Defects Res A Clin Mol Teratol 73:72-82. 2005
  8. pmc Excessive S-adenosyl-L-methionine-dependent methylation increases levels of methanol, formaldehyde and formic acid in rat brain striatal homogenates: possible role in S-adenosyl-L-methionine-induced Parkinson's disease-like disorders
    Eun Sook Lee
    Department of Neurology, Meharry Medical College, Nashville, TN 37208, United States
    Life Sci 83:821-7. 2008
  9. ncbi Chloroformates in gas chromatography as general purpose derivatizing agents
    P Husek
    Institute of Endocrinology, Prague, Czech Republic
    J Chromatogr B Biomed Sci Appl 717:57-91. 1998
  10. ncbi Simultaneous analysis of amino and nonamino organic acids as methyl chloroformate derivatives using gas chromatography-mass spectrometry
    Silas Granato Villas-Bôas
    Center for Process Biotechnology, BioCentrum DTU, Technical University of Denmark, Building 223, DK 2800 Kongens Lyngby, Denmark
    Anal Biochem 322:134-8. 2003

Detail Information

Publications236 found, 100 shown here

  1. ncbi Efficient hydrogenation of organic carbonates, carbamates and formates indicates alternative routes to methanol based on CO2 and CO
    Ekambaram Balaraman
    Department of Organic Chemistry, The Weizmann Institute of Science, Rehovot, 76100, Israel
    Nat Chem 3:609-14. 2011
    Catalytic hydrogenation of organic carbonates, carbamates and formates is of significant interest both conceptually and practically, because these compounds can be produced from CO2 and CO, and their mild hydrogenation can provide ..
  2. pmc Formate as the main branch point for methylotrophic metabolism in Methylobacterium extorquens AM1
    Gregory J Crowther
    Department of Chemical Engineering, University of Washington, Box 355014, Seattle, Washington 98195 5014, USA
    J Bacteriol 190:5057-62. 2008
    ..These results all support the suggestion that formate, not formaldehyde, is the main branch point for methylotrophic metabolism in M. extorquens AM1...
  3. ncbi The molecular biology of formate metabolism in enterobacteria
    Susanne Leonhartsberger
    Institute of Genetics and Microbiology, University of Munich
    J Mol Microbiol Biotechnol 4:269-76. 2002
    ..This review summarises the information on the biochemistry of synthesis and degradation of formate, on the genetics of the members of the regulon and on the mechanism underlying the regulation...
  4. ncbi Development of an insertional expression vector system for Methylobacterium extorquens AM1 and generation of null mutants lacking mtdA and/or fch
    Christopher J Marx
    Department of Microbiology, University of Washington, Seattle, WA 98195, USA
    Microbiology 150:9-19. 2004
    ....
  5. ncbi Elevated formic acid concentrations in putrefied post-mortem blood and urine samples
    Jenni Viinamäki
    Hjelt Institute, Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
    Forensic Sci Int 208:42-6. 2011
    ..Poor correlation was shown between blood and urine concentrations of FA. Poor correlations were also shown, in both blood and urine, between methanol and FA concentrations...
  6. ncbi Methanol toxicity and formate oxidation in NEUT2 mice
    R J Cook
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 0146, USA
    Arch Biochem Biophys 393:192-8. 2001
    ..The implications of these observations are discussed in terms of the current hypotheses concerning methanol and formate toxicity in rodents and primates...
  7. ncbi Methanol, formaldehyde, and sodium formate exposure in rat and mouse conceptuses: a potential role of the visceral yolk sac in embryotoxicity
    Jason M Hansen
    Department of Biochemistry, School of Medicine, Emory University, Atlanta, Georgia, USA
    Birth Defects Res A Clin Mol Teratol 73:72-82. 2005
    ..Methanol (CH3OH) is believed to be teratogenic based on rodent studies. The mouse is more sensitive than the rat, but mechanisms of toxicity and identification of teratogenic metabolites are uncertain...
  8. pmc Excessive S-adenosyl-L-methionine-dependent methylation increases levels of methanol, formaldehyde and formic acid in rat brain striatal homogenates: possible role in S-adenosyl-L-methionine-induced Parkinson's disease-like disorders
    Eun Sook Lee
    Department of Neurology, Meharry Medical College, Nashville, TN 37208, United States
    Life Sci 83:821-7. 2008
    ....
  9. ncbi Chloroformates in gas chromatography as general purpose derivatizing agents
    P Husek
    Institute of Endocrinology, Prague, Czech Republic
    J Chromatogr B Biomed Sci Appl 717:57-91. 1998
    ..Results of optimized reaction conditions and a wide range of applications of chloroformate-mediated derivatization in various disciplines have been summarized in this review...
  10. ncbi Simultaneous analysis of amino and nonamino organic acids as methyl chloroformate derivatives using gas chromatography-mass spectrometry
    Silas Granato Villas-Bôas
    Center for Process Biotechnology, BioCentrum DTU, Technical University of Denmark, Building 223, DK 2800 Kongens Lyngby, Denmark
    Anal Biochem 322:134-8. 2003
  11. pmc Methylotrophy in Methylobacterium extorquens AM1 from a genomic point of view
    Ludmila Chistoserdova
    Department of Chemical Engineering, University of Washington, Seattle, Washington 98195 2125, USA
    J Bacteriol 185:2980-7. 2003
  12. pmc Site-specific labeling of nucleotides for making RNA for high resolution NMR studies using an E. coli strain disabled in the oxidative pentose phosphate pathway
    T Kwaku Dayie
    Department of Chemistry and Biochemistry, Center for Biomolecular Structure and Organization, University of Maryland, 1115 Biomolecular Sciences Bldg 296, College Park, MD 20742 3360, USA
    J Biomol NMR 47:19-31. 2010
    ....
  13. pmc An unusual carbon-carbon bond cleavage reaction during phosphinothricin biosynthesis
    Robert M Cicchillo
    Department of Chemistry, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    Nature 459:871-4. 2009
    ..The current study expands the scope of reactions catalysed by the 2-His-1-carboxylate mononuclear non-haem iron family of enzymes...
  14. ncbi Effect of dietary formates on growth performance, carcass traits, sensory quality, intestinal microflora, and stomach alterations in growing-finishing pigs
    M Overland
    Department of Animal Science, Agricultural University of Norway, As
    J Anim Sci 78:1875-84. 2000
    ..In conclusion, K-diformate improved growth performance and carcass quality of growing-finishing pigs, whereas Ca/Na-formate had no effect. K-diformate had no adverse effect on sensory quality of pork or on stomach alteration scores...
  15. pmc Identification of a fourth formate dehydrogenase in Methylobacterium extorquens AM1 and confirmation of the essential role of formate oxidation in methylotrophy
    Ludmila Chistoserdova
    Department of Chemical Engineering, University of Washington, Seattle, Washington 98195, USA
    J Bacteriol 189:9076-81. 2007
    ..Mutation of a small open reading frame (fdh4B) downstream of fdh4A resulted in mutant phenotypes similar to the phenotypes of fdh4A mutants, suggesting that fdh4B is also involved in formate oxidation...
  16. ncbi Cytotoxic effects of methanol, formaldehyde, and formate on dissociated rat thymocytes: a possibility of aspartame toxicity
    Y Oyama
    Laboratory of Cellular Signaling, Faculty of Integrated Arts and Sciences, The University of Tokushima, Japan
    Cell Biol Toxicol 18:43-50. 2002
    ..It is suggested that aspartame at abuse doses is harmless to humans...
  17. pmc Multiple formate dehydrogenase enzymes in the facultative methylotroph Methylobacterium extorquens AM1 are dispensable for growth on methanol
    Ludmila Chistoserdova
    Department of Chemical Engineering, University of Washington, Seattle, Washington 98195 2180, USA
    J Bacteriol 186:22-8. 2004
    ....
  18. pmc Acetate and formate stress: opposite responses in the proteome of Escherichia coli
    C Kirkpatrick
    Department of Biology, Kenyon College, Gambier, Ohio 43022, USA
    J Bacteriol 183:6466-77. 2001
    ....
  19. ncbi Bioavailability and lack of toxicity of S-adenosyl-L-methionine (SAMe) in humans
    Jessica L Goren
    Psychopharmacology Research Laboratory, Program for the Development of Natural and Novel Treatments for Bipolar Disorder, McLean Hospital, Belmont, Massachusetts
    Pharmacotherapy 24:1501-7. 2004
    ..Serum homocysteine levels were also measured since alterations in these levels have been theorized in association with SAMe...
  20. ncbi An improved synthesis of a trifurcated newkome-type monomer and orthogonally protected two-generation dendrons
    Claudia M Cardona
    Department of Chemistry and NIEHS Marine and Freshwater Biomedical Sciences Center, University of Miami, P O Box 249118, Coral Gables, Florida 33124 0431, USA
    J Org Chem 67:1411-3. 2002
    ..The Cbz protecting group may be removed from the second-generation dendron without disturbing the tert-butyl esters of the periphery...
  21. ncbi Repression of formate dehydrogenase in Solanum tuberosum increases steady-state levels of formate and accelerates the accumulation of proline in response to osmotic stress
    Françoise Ambard-Bretteville
    Institut de Biotechnologie des Plantes UMR CNRS 8618, Universite Paris Sud, 91405 Orsay Cedex, France
    Plant Mol Biol 52:1153-68. 2003
    ..Amongst various biochemical and molecular differences between stressed AS23 and control plants, the most striking was a dramatically faster accumulation of proline in the leaves of drought-stressed plants under-expressing FDH...
  22. ncbi New hydrogen donor: a facile method for the removal of hydrogenolysable protecting groups in Peptide synthesis
    D Channe Gowda
    Department of Studies in Chemistry, University of Mysore, Manasagangotri, Karnataka, India
    Protein Pept Lett 9:225-30. 2002
    ..tert-Butyl derived and base labile protecting groups were completely stable under these conditions. This is more effective than hydrazine or formic acid...
  23. ncbi Regio- and stereoselective anomeric esterification of glucopyranose 1,2-diols and a facile preparation of 2-O-acetylated glucopyranosyl trichloroacetimidates from the corresponding 1,2-diols
    Jianjun Zhang
    Key Lab of Pesticide Chemistry and Application Technology, Department of Applied Chemistry, China Agricultural University, Beijing 100094, China
    Carbohydr Res 342:797-805. 2007
    ....
  24. ncbi Palladium-catalyzed regio- and stereoselective formate reduction of fluorine-containing allylic mesylates. A new entry for the construction of a tertiary carbon attached with a fluoroalkyl group
    Tsutomu Konno
    Department of Chemistry and Materials Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    J Org Chem 71:3545-50. 2006
    ..When the chiral allylic ester was employed, complete chirality transfer was observed, leading to the optically active materials in high yields...
  25. ncbi Gas chromatographic analysis of amino acid enantiomers in Carbetocin peptide hydrolysates after fast derivatization with pentafluoropropyl chloroformate
    H Zahradnícková
    Biology Centre, Academy of Sciences of the Czech Republic, Laboratory of Analytical Biochemistry, Ceske Budejovice, Czech Republic
    Amino Acids 35:445-50. 2008
    ..The approach was found beneficial for chiral analysis of pharmaceutically important Carbetocin peptide...
  26. ncbi Modification of allergenicity and immunogenicity of formate dehydrogenase by conjugation with linear mono methoxy poly ethylene glycol: improvement in detoxification of formate in methanol poisoning
    A Muthuvel
    Department of Physiology, Dr A L M Postgraduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai 600113, Tamilnadu, India
    Clin Chim Acta 374:122-8. 2006
    ....
  27. ncbi Cobas Mira S endpoint enzymatic assay for plasma formate
    B Blomme
    Department of Clinical Chemistry--Toxicology, Academic Hospital Free University Brussels, Belgium
    J Anal Toxicol 25:77-80. 2001
    ..The frozen reagents are stable for at least six months, so the described method can be applied to irregular and semi-urgent requests. A recent case is reported...
  28. ncbi EPR characterization of the molybdenum(V) forms of formate dehydrogenase from Desulfovibrio desulfuricans ATCC 27774 upon formate reduction
    Maria G Rivas
    REQUIMTE CQFB, Departamento de Quimica, Faculdade de Ciencias e Tecnologia, Universidade Nova de Lisboa, 2829 516 Monte de Caparica, Portugal
    J Inorg Biochem 101:1617-22. 2007
    ....
  29. ncbi Hydrogenases and formate dehydrogenases of Syntrophobacter fumaroxidans
    F A M de Bok
    Laboratory of Microbiology, Wageningen University, The Netherlands
    Antonie Van Leeuwenhoek 81:283-91. 2002
    ..These findings suggest that both H2 and formate are involved in the central metabolism of the organism, and that both these compounds may serve as interspecies electron carriers during syntrophic growth on propionate...
  30. ncbi Real-time monitoring of the oxalate decarboxylase reaction and probing hydron exchange in the product, formate, using fourier transform infrared spectroscopy
    Mylrajan Muthusamy
    Biological Chemistry Department, John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, United Kingdom
    Biochemistry 45:10667-73. 2006
    ..This restricts the formation of potentially harmful radical intermediates to the forward reaction...
  31. ncbi The 13C chemical shift tensor principal values and orientations in dialkyl carbonates and trithiocarbonates
    Dirk Stueber
    Department of Chemistry, University of Utah, 315 S 1400 E, Salt Lake City, Utah 84112 0850, USA
    Solid State Nucl Magn Reson 22:439-57. 2002
    ..The chemical shift tensor orientations and principal values obtained for the dialkyl compounds in this study complement the previous data on a series of ionic potassium carbonates and thiocarbonates...
  32. ncbi The chemistry of dimethyl carbonate
    Pietro Tundo
    Dipartimento di Scienze Ambientali, Università Cà Foscari, Dorsoduro 2137 30123 Venezia, Italy
    Acc Chem Res 35:706-16. 2002
    ..e., diethyl and dibenzyl carbonate), are excellent mono-C- and mono-N-alkylating agents, whereas asymmetrical methyl alkyl carbonates (ROCO(2)Me with R > or = C(3)) undergo methylation processes with a chemoselectivity up to 99%...
  33. ncbi FTIR and FTR spectral studies of 2-amino-6-bromo-3-formylchromone
    V Arjunan
    Department of Chemistry, Tagore Arts College, Pondicherry 605 008, India
    Spectrochim Acta A Mol Biomol Spectrosc 60:995-1000. 2004
    ..A normal coordinate analysis has been performed to characterise the vibrational fundamentals in terms of potential energy distribution (PED)...
  34. ncbi Transfer hydrogenation using recyclable polymer-supported formate (PSF): efficient and chemoselective reduction of nitroarenes
    Basudeb Basu
    Department of Chemistry, North Bengal University, Darjeeling, 734 430, India
    Mol Divers 9:259-62. 2005
    ..The procedure is chemoselective for nitro group; ester, ketone, aldehyde, and halide substituents on aromatic ring remain unaffected...
  35. ncbi Predicting the reactivity of ambidentate nucleophiles and electrophiles using a single, general-purpose, reactivity indicator
    James S M Anderson
    Department of Chemistry, McMaster University, Hamilton, Ontario, CanadaL8S 4M1
    Phys Chem Chem Phys 9:2371-8. 2007
    ..For electrophiles we consider dimethyl carbonate, N-methyl-N-nitrosotoluene-p-sulfonamide (MNTS), and 1-chloro-2,4,6-trinitrobenzene (CNB)...
  36. ncbi Mechanistic studies on the lysine-induced N-formylation of 2,5-dimethyl-p-benzoquinonediimine
    Joan Eilstein
    Institut de Chimie de Strasbourg, Université Louis Pasteur CNRS ULP, Laboratoire de Dermatochimie, Clinique Dermatologique CHU, 67091 Strasbourg, France
    Chem Res Toxicol 20:1155-61. 2007
    ..This initially unexpected behavior should be considered when investigating the reactivity of such compounds with lysine-containing peptides or proteins in the context of hapten-protein binding studies...
  37. ncbi Formate ion decomposition in water under UV irradiation at 253.7 nm
    Gonca F Talu
    Department of Civil Engineering, City College of New York, and the Graduate Center of the City University of New York, Convent Avenue at 138th Street, New York, New York 10031, USA
    Environ Sci Technol 38:3984-93. 2004
    ..HCO2- decomposed readily until [HCO2-] approximately equal to MDL but at a lower rate than in buffer-free HCO2- solutions, while C2O4(2-) remained virtually unchanged. C2O4(2-) decay commenced following near complete conversion of HCO2-...
  38. pmc New biphenol-based, fine-tunable monodentate phosphoramidite ligands for catalytic asymmetric transformations
    Zihao Hua
    Department of Chemistry, Stony Brook University, Stony Brook, NY 11794 3400, USA
    Proc Natl Acad Sci U S A 101:5411-6. 2004
    ..The fine-tuning capability of these ligands plays a significant role in achieving high enantioselectivity in the asymmetric hydroformylation of allyl cyanide and the conjugate addition of diethylzinc to cycloalkenones...
  39. ncbi Four new compounds from the leaves of Acer truncatum
    Lang Ping Dong
    State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, The Chinese Academy of Sciences, Kunming 650204, Yunnan, PR China
    Chem Biodivers 3:791-8. 2006
    ..Their structures were elucidated on the basis of extensive spectroscopic techniques. The absolute configuration of compound 3 was established by the modified Mosher's method. All compounds were evaluated for antibacterial activities...
  40. ncbi Composite hybrid membrane of chitosan-silica in pervaporation separation of MeOH/DMC mixtures
    Jian Hua Chen
    Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China
    J Colloid Interface Sci 316:580-8. 2007
    ..The CSHM presents superior separation behaviors over other membranes with a flux of 1265 g/(hm(2)) and separation factor of 30.1 in PV separation of 70 wt% MeOH in feed at 50 degrees C...
  41. ncbi Interactions of photosystem II with bicarbonate, formate and acetate
    Dmitriy Shevela
    Max Planck Institut fur Bioanorganische Chemie, Stiftstrasse 34 36, 45470, Mulheim an der Ruhr, Germany
    Photosynth Res 94:247-64. 2007
    ..These data are discussed in detail by also taking into account the CO2 concentrations present in the buffers after argon bubbling and during the measurements. These values were measured by membrane-inlet mass spectrometry (MIMS)...
  42. ncbi Asymmetric hydroformylation with highly crosslinked polystyrene-supported (R,S)-BINAPHOS-Rh(I) complexes: the effect of immobilization position
    Fumitoshi Shibahara
    Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Hongo Bunkyo ku, Japan
    Bioorg Med Chem Lett 12:1825-7. 2002
    ..Using its Rh(I) complex, asymmetric hydroformylation of olefins proceeded with higher enantioselectivity in some cases compared to the conventional polymer-supported 1c...
  43. ncbi A multi-component reaction to 5-cyanouracils: synthesis and mechanistic study
    Bo Ren Zhuang
    Department of Chemistry, National Cheng Kung University, Tainan, Taiwan, ROC
    Bioorg Med Chem 14:3399-404. 2006
    ..General-base-catalyzed intramolecular cyclizations of Z-3a-c at a reflux condition in CD3CN generated the corresponding 5-cyanouracils 4a-c...
  44. ncbi High yield regioselective monobenzyloxycarbonylation of secondary alcohols in glycopyranoside series
    Alain Morere
    Laboratoire de Chimie Biomoléculaire UMR 5032, Université Montpellier II ENSCM, 8 rue de l Ecole Normale, F 3429 Montpellier, France
    Carbohydr Res 338:2409-12. 2003
    ..2.2]octane...
  45. ncbi Methylohalomonas lacus gen. nov., sp. nov. and Methylonatrum kenyense gen. nov., sp. nov., methylotrophic gammaproteobacteria from hypersaline lakes
    Dimitry Yu Sorokin
    Winogradsky Institute of Microbiology, Russian Academy of Sciences, Prospect 60 let Octyabrya 7 2, 117811 Moscow, Russia
    Int J Syst Evol Microbiol 57:2762-9. 2007
    ..nov., sp. nov. (type strain AMT 1(T) =DSM 15732(T) =NCCB 100209(T) =UNIQEM U238(T))...
  46. ncbi New developments in SPME, Part 1: The use of vapor-phase deprotonation and on-fiber derivatization with alkylchloroformates in the analysis of preparations containing amphetamines
    Hayley Brown
    Flinders University of South Australia, GPO Box 2100, Adelaide, South Australia
    J Forensic Sci 48:1231-8. 2003
    ..This extra step was included to improve the chromatographic performance of analytes and allow for the resolution of drug enantiomers...
  47. ncbi Presence of tetrahydro-beta-carboline-3-carboxylic acids in foods by gas chromatography-mass spectrometry as their N-methoxycarbonyl methyl ester derivatives
    T Herraiz
    Instituto de Fermentaciones Industriales, CSIC, Madrid, Spain
    J Chromatogr A 765:265-77. 1997
    ..These results prove the presence of TH beta C-3-COOHs in commercial foodstuffs suggesting their uptake during the daily consumption of foods...
  48. ncbi Synthesis of azoxabicyclo[3.3.1]nonanones based on diastereoselective reactions of 1,1-bis(trimethylsilyloxy)ketene acetals with isoquinolines and quinolines
    Andreas Schmidt
    Institut fur Chemie, Universitat Rostock, Rostock, Germany
    Org Biomol Chem 6:2804-14. 2008
    ..3.1]nonanones were prepared by regio- and diastereoselective condensation of 1,1-bis(silyloxy)ketene acetals with isoquinolinium and quinolinium salts and subsequent regioselective and stereospecific iodolactonization...
  49. pmc A two stage click-based library of protein tyrosine phosphatase inhibitors
    Jian Xie
    Department of Chemistry, Brown University, 324 Brook St Box H, Providence, RI 02912, USA
    Bioorg Med Chem 15:458-73. 2007
    ..The most potent inhibitor containing a single alpha-ketocarboxylic acid group 32 had IC(50) values of 2.1, 5.7, and 2.6 microM against the Yersinia PTP, PTP1B, and TCPTP, respectively...
  50. ncbi Rapid determination of amino acids in neonatal blood samples based on derivatization with isobutyl chloroformate followed by solid-phase microextraction and gas chromatography/mass spectrometry
    Chunhui Deng
    Department of Chemistry, Fudan University, Shanghai 200433, P R China
    Rapid Commun Mass Spectrom 18:2558-64. 2004
    ..The results showed that the proposed method is a potentially powerful tool for simultaneous screening for neonatal PKU and MSUD...
  51. ncbi Gas chromatographic amino acid profiling of wine samples for pattern recognition
    K R Kim
    College of Pharmacy, Sungkyunkwan University, Suwon, South Korea
    J Chromatogr A 722:303-9. 1996
    ..Stepwise discriminant analysis performed on the amino acid profiles provided star symbols characteristic of the wine brands...
  52. pmc Coordinate regulation of the Escherichia coli formate dehydrogenase fdnGHI and fdhF genes in response to nitrate, nitrite, and formate: roles for NarL and NarP
    Henian Wang
    Department of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, 1602 Molecular Sciences Building, Los Angeles, CA 90095, USA
    J Bacteriol 185:5076-85. 2003
    ..Revised regulatory schemes for NarL- and NarP-dependent nitrate control are presented for each operon...
  53. ncbi Photocatalytic degradation of pollutants from Elcogas IGCC power station effluents
    A Duran
    Department of Chemical Engineering, Escuela Técnica Superior de Ingenieros Industriales, University of Castilla La Mancha, Avda Camilo José Cela 3, 13071 Ciudad Real, Spain
    J Hazard Mater 144:132-9. 2007
    ..the different catalysts (TiO(2) and ZnO) was determined from the analysis of the following parameters: cyanides, formates and ammonia content...
  54. ncbi Do stable nitroxide radicals catalyze or inhibit the degradation of hyaluronic acid?
    Ziva Lurie
    Department of Molecular Biology, Hebrew University Hadassah Medical School, Jerusalem, Israel
    Free Radic Biol Med 35:169-78. 2003
    ..The protective effect is attributable neither to the scavenging of OH nor to the oxidation of reduced metal, but to the reaction of nitroxides with secondary carbohydrate radicals-most likely peroxyl radicals...
  55. ncbi Dimethylcarbonate for eco-friendly methylation reactions
    S Memoli
    Interuniversity, Consortium Chemistry for the Environment, Venice, Marghera, Italy
    Chemosphere 43:115-21. 2001
    ..The highly selective O-methylation of phenols and p-cresols by DMC is also attained by a new methodology using a continuous fed stirred tank reactor (CSTR) filled with a catalytic bed of polyethyleneglycol (PEG) and potassium carbonate...
  56. ncbi Dissection of nucleophilic and acid-base catalysis in glycosidases
    D L Zechel
    Protein Engineering Network of Centres of Excellence of Canada and Department of Chemistry, University of British Columbia, Vancouver, Canada
    Curr Opin Chem Biol 5:643-9. 2001
    ..These studies provide an interesting bridge between enzymes and models thereof...
  57. ncbi The local environment of Cu+ in Cu-Y zeolite and its relationship to the synthesis of dimethyl carbonate
    Ian J Drake
    Department of Chemical Engineering, University of California, Berkeley, California 94720 1462, USA
    J Phys Chem B 110:11654-64. 2006
    ..The dominant adsorbed species on the surface are methoxy groups, and adsorbed CO is present as a minority species. The relationship of these observations to the kinetics of DMC synthesis is discussed...
  58. pmc Site-selective catalysis of phenyl thionoformate transfer as a tool for regioselective deoxygenation of polyols
    María Sánchez-Roselló
    Department of Chemistry, Yale University, PO Box 208107, New Haven, Connecticut 06520 8107, USA
    J Org Chem 73:1774-82. 2008
    ..Through screening of peptides and control of reaction conditions, products could be observed that reflected both the inherent preference of substrates and also reversal of inherent selectivity...
  59. ncbi Experimental modeling of the cathode reduction of carbon dioxide on pyrite in deep hydrothermal vents
    M G Vladimirov
    Bach Institute of Biochemistry, Russian Academy of Sciences, Leninskii pr 33, Moscow, 117071 Russia
    Dokl Biochem Biophys 385:205-8. 2002
  60. ncbi Binding of D-mannose to poly(2-hydroxyethyl methacrylate) hydrogels by azo coupling
    Jirí Labský
    Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, Heyrovsky Sq 2, 162 06 Prague 6, Czech Republic
    Biomaterials 24:4031-6. 2003
    ....
  61. ncbi Evaluation of volatile low molecular weight insecticides using Drosophila melanogaster as a model
    Michael E Scharf
    Entomology and Nematology Department, University of Florida, Gainesville, FL 32611, USA
    Pest Manag Sci 62:655-63. 2006
    ..against coleopteran stored product pests, caused toxicity in Drosophila but was not as effective as other tested formates. Two volatile fumigant insecticides, dichlorvos (DDVP) and methyl isothiocyanate (MITC), were also tested as ..
  62. ncbi Cytochrome c oxidase inhibition in the rice weevil Sitophilus oryzae (L.) by formate, the toxic metabolite of volatile alkyl formates
    V S Haritos
    CSIRO Entomology, G P O Box 1700, Canberra ACT 2601, Australia
    Comp Biochem Physiol C Toxicol Pharmacol 136:135-43. 2003
    Volatile alkyl formates are potential replacements for the ozone-depleting fumigant, methyl bromide, as postharvest insecticides and here we have investigated their mode of insecticidal action...
  63. ncbi Cl atom-initiated oxidation of three homologous methyl perfluoroalkyl ethers
    K Nohara
    New Refrigerants Development Group, Research Institute of Innovative Technology for the Earth, Tsukuba, Ibaraki, Japan
    Environ Sci Technol 35:114-20. 2001
    ..For oxidation of the three ethers, perfluoroalkyl formates (C(n)F(2n+1)OCHO; n = 2, 3 and 5) as relatively stable intermediates were produced at unity of the production ..
  64. ncbi Synthesis and thermolytic behavior of tin(IV) formates: in search of recyclable metal-hydride systems
    Bobby D Ellis
    University of California, Department of Chemistry, Davis, CA 95616, USA
    Dalton Trans 39:10659-63. 2010
    The synthesis and characterization of the series of organotin formates together with their thermolytic behavior are described. The diformate Bu(n)(2)Sn{OC(O)H}(2) (1) was synthesized by the reaction of Bu(n)(2)SnH(2) with formic acid...
  65. ncbi Pure component spectral analysis of surface adsorbed species measured under real conditions. BTEM-DRIFTS study of CO and NO reaction over a Pd/gamma-Al2O3 catalyst
    Srilakshmi Chilukoti
    Institute of Chemical and Engineering Sciences, 1 Pesek Road, Jurong Island, Singapore, 627833
    Phys Chem Chem Phys 10:5510-20. 2008
    ..e. nitrates, nitrites, carbonates, bicarbonates, formates, and isocyanates) as well as gas phase species...
  66. ncbi Photocatalytic treatment of IGCC power station effluents in a UV-pilot plant
    A Duran
    Grupo IMAES, Department of Chemical Engineering, Escuela Técnica Superior de Ingenieros Industriales, University of Castilla La Mancha, Avenida Camilo José Cela 3, Ciudad Real, Spain
    J Hazard Mater 167:885-91. 2009
    ..The efficiency of the process was determined from the analysis of the following parameters: cyanides, formates and TOC content...
  67. ncbi Solution synthesis and characterization of indium-zinc formate precursors for transparent conducting oxides
    Robert M Pasquarelli
    Colorado School of Mines, Metallurgical and Materials Engineering, 1500 Illinois Street, Golden, Colorado 80401, USA
    Inorg Chem 49:5424-31. 2010
    ..Thermal analysis revealed that a mixture of In and Zn formates reduced the overall decomposition temperature compared to the individual constituents and that OH-substitution ..
  68. ncbi Stability of formate species on beta-Ga2O3
    M Calatayud
    , UMR 7616 CNRS, , , 4 Place Jussieu Paris, 75252 Cedex 05, France
    Phys Chem Chem Phys 11:1397-405. 2009
    ..Monocoordinate formates are thus short-lived intermediates playing a key role in the CO oxidation reaction, while bidentate formates are ..
  69. ncbi Treatment of IGCC power station effluents by physico-chemical and advanced oxidation processes
    A Duran
    Department of Chemical Engineering, Escuela Técnica Superior de Ingenieros Industriales, University of Castilla La Mancha, Avda Camilo José Cela 3, 13071 Ciudad Real, Spain
    J Environ Manage 90:1370-6. 2009
    ..process was effective for total cyanide destruction after 60 min, while 180 min was needed to remove 80% of formates. However, a more simple system with UV/H2O2/O2 yields similar results and is preferred for industrial application ..
  70. ncbi Corrosion by bacteria of concrete in sewerage systems and inhibitory effects of formates on their growth
    Tateo Yamanaka
    Department of Materials and Applied Chemistry, College of Sciences and Technology, Nihon University, Kanda Surugadai, Tokyo, Japan
    Water Res 36:2636-42. 2002
    ..The growth of the sulfur-oxidizing and acidophilic iron-oxidizing bacteria was completely inhibited by formates, especially by calcium formate of concentrations more than 50 mM...
  71. ncbi CO2 template synthesis of metal formates with a ReO3 net
    Yun Qi Tian
    Institute of Chemistry for Functionalized Materials, College of Chemistry and Engineering, Liaoning Normal University, Dalian 116029, China
    Inorg Chem 46:1612-6. 2007
    ..of CO2 as a template in the fabrication of ferric formate (1) has led to the preparation of serial metal(III) formates [MIII(HCOO)3.3/4CO2.1/4H2O.1/4HCOOH ]infinity (M = Fe(1), Al (2), Ga (3), and In(4))...
  72. ncbi Bridge-bonded formate: active intermediate or spectator species in formic acid oxidation on a Pt film electrode?
    Y X Chen
    Institute of Surface Chemistry and Catalysis, Ulm University, D 89069 Ulm, Germany
    Langmuir 22:10399-408. 2006
    ..mass transport conditions, which specifically aimed at elucidating the role of the adsorbed bridge-bonded formates in this reaction...
  73. ncbi Photocatalytic degradation of formaldehyde containing wastewater from veterinarian laboratories
    J Arana
    Photocatalysis and Electrochemical Laboratory, Parque Científico y Tecnológico, Universidad de Las Palmas de Gran Canaria, Tafira Campus, E 35017 Las Palmas de Gran Canaria, Spain
    Chemosphere 55:893-904. 2004
    ..Results indicate that at high concentrations the catalyst surfacial alterations given by methoxy, formates or carbonates, according to the pH of the sample can profoundly affect catalyst behaviour...
  74. ncbi New heterometallic [Mn(III)(4)Ln(III)(4)] wheels incorporating formate ligands
    Mengyuan Li
    , Engessserstr 15, Karlsruhe Institute for Technologie, D 76131 Karlsruhe, Germany
    Dalton Trans 39:3375-7. 2010
    ..complexes with an eight-membered saddle-like ring of [Mn(III)(4)Ln(III)(4)] (Ln = Dy, Gd), prepared by employing formates as key carboxylate bridges, exhibit antiferromagnetic interactions between Mn(III) and Ln(III) centers, and the ..
  75. ncbi The hydroarylation reaction--scope and limitations
    Jan C Namyslo
    Institute of Organic Chemistry, Clausthal University of Technology, Leibnizstr 6, D 38678 Clausthal Zellerfeld, Germany
    Molecules 15:3402-10. 2010
    ..When a tetracyclic cis-allylcyclopropane is carbopalladated in the presence of formates, the neighboring cyclopropane ring is attacked in the first reported example of a pi,sigma domino-Heck reaction.
  76. ncbi Kinetic and mechanistic study of the gas-phase reactions of a series of vinyl ethers with the nitrate radical
    Michaël Scarfogliero
    Laboratoire Interuniversitaire des Systemes Atmospheriques, UMR CNRS 7583, Universite Paris 12, 94010 Creteil Cedex
    J Phys Chem A 110:11074-81. 2006
    ..oxidation products have been identified like being formaldehyde and respectively methyl, ethyl, propyl, and butyl formates. Production yields of oxidation products were close to 50%...
  77. ncbi Degradation of formaldehyde at high concentrations by phenol-adapted Ralstonia eutropha closely related to pink-pigmented facultative methylotrophs
    Alireza Habibi
    Chemical Engineering Department, Amirkabir University of Technology, Tehran, Iran
    J Environ Sci Health A Tox Hazard Subst Environ Eng 48:279-92. 2013
    ..The extent of harm to soil exposed to biotreated wastewaters containing FD may be moderated due to the association between methylotrophic/oxalotrophic bacteria and plants...
  78. ncbi Effect of acidic condition on the metabolic regulation of Escherichia coli and its phoB mutant
    Lolo Wal Marzan
    Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, Iizuka, Fukuoka 820 8502, Japan
    Arch Microbiol 195:161-71. 2013
    ..The overall regulation mechanism under acidic condition was clarified based on fermentation characteristics and gene transcript levels...
  79. ncbi Towards a practical setup for hydrogen production from formic acid
    Peter Sponholz
    Leibniz Institut für Katalyse eV an der Universität Rostock, Rostock, Germany
    ChemSusChem 6:1172-6. 2013
    ..By using an in situ-formed ruthenium catalyst, unprecedented turnover numbers over 1,000,000 are achieved. The active catalyst is formed in situ from commercially available [RuCl2 (benzene)]2 and 1,2-bisdiphenylphosphinoethane...
  80. ncbi Role of vibrational anharmonicity in atmospheric radical hydrogen-bonded complexes
    M Torrent-Sucarrat
    Eenheid Algemene Chemie ALGC, Faculteit Wetenschappen Vrije Universiteit Brussel Pleinlaan 2, 1050 Brussels, Belgium
    Phys Chem Chem Phys 11:6377-88. 2009
    ..The anharmonic contribution results in differences of around 40 cm(-1) with respect to the harmonic values; although in some cases involving highly anharmonic modes, these differences can rise up to 300 and 450 cm(-1)...
  81. ncbi Mechanical properties and antibacterial efficacy of chitosan films
    Teruo Nakashima
    Institute of Resource Recycling, Kinki University, Faculty of Agriculture, 3327 204, Nakamachi, Nara 631 8505, Japan
    Biocontrol Sci 11:27-36. 2006
    ....
  82. ncbi Desulfovibrio alkalitolerans sp. nov., a novel alkalitolerant, sulphate-reducing bacterium isolated from district heating water
    Lone Abildgaard
    Department of Microbiology, Institute of Biological Sciences, University of Aarhus, Denmark
    Int J Syst Evol Microbiol 56:1019-24. 2006
    ..nov. is proposed. The type strain is RT2T (=DSM 16529T=JCM 12612T). The strain is the first alkali-tolerant member of the genus Desulfovibrio to be described...
  83. ncbi Metabolic engineering of Escherichia coli to minimize byproduct formate and improving succinate productivity through increasing NADH availability by heterologous expression of NAD(+)-dependent formate dehydrogenase
    Grant J Balzer
    Department of Bioengineering, Rice University, Houston, TX 77005, USA
    Metab Eng 20:1-8. 2013
    ..Reduced levels of byproduct formate in succinate fermentation broth would provide an opportunity for reducing the cost associated with downstream processing, purification, and waste disposal...
  84. ncbi Transmissibility of mouse AApoAII amyloid fibrils: inactivation by physical and chemical methods
    Huanyu Zhang
    Department of Aging Biology, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine, Asahi 3 1 1, Matsumoto 390 8621, Japan
    FASEB J 20:1012-4. 2006
    ..AApoAII amyloidosis provides a valuable system for studying factors that may prevent transmission of amyloid disease as well as potential novel therapies...
  85. ncbi [Decalcification of bone and dental specimens using formic acid aluminum chloride decalcifying fluid]
    Shi quan Xue
    Zhonghua Bing Li Xue Za Zhi 35:372-3. 2006
  86. ncbi Experimental and theoretical charge densities of a zinc-containing coordination polymer, Zn(HCOO)2(H2O)2
    Mads R V Jørgensen
    Center for Materials Crystallography, Department of Chemistry and iNANO, Aarhus University, Langelandsgade 140, DK 8000 Aarhus C, Denmark
    Inorg Chem 52:297-305. 2013
    ..The source function calculated at the bond critical points reveals a rather delocalized picture of the density in the bridging carboxylates, and this presumably reflects the exchange pathway in the magnetic analogues...
  87. ncbi Synthesis and characterization of a novel molecularly imprinted polymer for simultaneous extraction and determination of water-soluble and fat-soluble synthetic colorants in chilli products by solid phase extraction and high performance liquid chromatogra
    Chaoyang Long
    Center for Disease Prevention and Control of Guangdong Province, Guangzhou 510300, China
    J Chromatogr A 1216:8379-85. 2009
    ..2-1.6 and 1.9-2.4 microg kg(-1) in chilli spice and chilli powder. The resulting MISPE was successfully used off-line for the determination of nine kinds of synthetic colorants in chilli products...
  88. ncbi The energy dependence of lithium formate EPR dosimeters for clinical electron beams
    Eirik Malinen
    Department of Medical Physics, The Norwegian Radium Hospital, N 0310 Oslo, Norway
    Phys Med Biol 52:4361-9. 2007
    ..In conclusion, lithium formate EPR dosimetry of clinical electron beams provides precise dose measurements with low dependence on the electron energy...
  89. ncbi The response of osteoblast-like cells towards collagen type I coating immobilized by p-nitrophenylchloroformate to titanium
    Juliette van den Dolder
    Department of Periodontology and Biomaterials, Radboud University Nijmegen Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    J Biomed Mater Res A 83:712-9. 2007
    ..Further, we conclude that an adsorbed collagen type I coating stimulated the osteoblastic differentiation of rat bone marrow cells...
  90. ncbi Investigation of methanol oxidation over Au/catalysts using operando IR spectroscopy: determination of the active sites, intermediate/spectator species, and reaction mechanism
    Séverine Rousseau
    Laboratoire Catalyse et Spectrochimie, ENSICAEN, Universite de Caen, CNRS, 14050 Caen, France
    J Am Chem Soc 132:10832-41. 2010
    ..kinds of methoxy species formed on the support were identified as intermediates, which further transform into formates whose oxidation was found to be the rate-determining step for the reaction...
  91. ncbi Biphasic microreactor for efficient membrane protein pretreatment with a combination of formic acid assisted solubilization, on-column pH adjustment, reduction, alkylation, and tryptic digestion
    Qun Zhao
    National Chromatographic R and A Center, Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Science, Dalian 116023, China
    Anal Chem 85:8507-12. 2013
    ..All these results demonstrated that such an "SCX-SAX" based biphasic microreactor could offer a promising tool for the pretreatment of trace membrane proteins with high efficiency and throughput. ..
  92. ncbi Conservation characteristics of wilted perennial ryegrass silage made using biological or chemical additives
    P Conaghan
    Teagasc, Grange Beef Research Centre, Dunsany, Co Meath, Ireland
    J Dairy Sci 93:628-43. 2010
    ....
  93. pmc Reversed-phase chromatography with multiple fraction concatenation strategy for proteome profiling of human MCF10A cells
    Yuexi Wang
    Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    Proteomics 11:2019-26. 2011
    ..The results demonstrate that the concatenated high pH reversed-phased strategy is an attractive alternative to strong cation exchange for two-dimensional shotgun proteomic analysis...
  94. ncbi Biosecurity aspects and pathogen inactivation in acidified high risk animal by-products
    Björn Vinnerås
    Department of Chemistry, Environment and Feed Hygiene, National Veterinary Institute, Uppsala, Sweden
    J Environ Sci Health A Tox Hazard Subst Environ Eng 47:1166-72. 2012
    ..In addition, there is a risk of transmission of the diseases anthrax and black leg, caused by sporulating bacteria...
  95. ncbi Fluoroalkyl chloroformates in treating amino acids for gas chromatographic analysis
    Petr Husek
    Biology Centre, Laboratory of Analytical Biochemistry, Academy of Sciences of the Czech Republic, Branisovska 31, CZ 370 05 Ceske Budejovice, Czech Republic
    J Chromatogr A 1186:391-400. 2008
    ..The novel method is simple, robust and rapid, enabling to treat amino acids in aqueous environment and to analyze them in <15 min...
  96. ncbi A photocatalyst-enzyme coupled artificial photosynthesis system for solar energy in production of formic acid from CO2
    Rajesh K Yadav
    Advanced Chemical Technology Division, Korea Research Institute of Chemical Technology, 100 Jang Dong, Yuseong, Daejon, 305 600, Republic of Korea
    J Am Chem Soc 134:11455-61. 2012
    ....
  97. ncbi Determination of amino acids in selenium-enriched yeast by gas chromatography-mass spectrometry after microwave assisted hydrolysis
    Xu Zhang
    National Research Council Canada, Ottawa, Ontario, Canada
    Anal Chim Acta 744:54-9. 2012
    ..Limits of detection and quantitation (LODs/LOQs) of the amino acids measured were in the sub-nmol range, suitable for monitoring of amino acids in yeast and other food products...
  98. ncbi Reversibly labile, sclerotization-induced elastic properties in a keratin analog from marine snails: whelk egg capsule biopolymer (WECB)
    H Scott Rapoport
    Marine Biology Research Division, Scripps Institution of Oceanography, La Jolla, CA 92093, USA
    J Exp Biol 210:12-26. 2007
    ..Keratin mechanical models were applied to WECB in its representation as an intermediate state between matrix-free intermediate filament (IF)-type proteins and the more complex composite materials incorporating IFs such as keratin...
  99. ncbi UV-induced carbonyl generation with formic acid for sensitive determination of nickel by atomic fluorescence spectrometry
    Liwei Liu
    College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, China
    Talanta 80:1239-44. 2010
    ..This is a simple, fairly green and highly sensitive method for ultra-trace nickel determination...
  100. ncbi Online preconcentration of recombinant Arg-Gly-Asp-hirudin using dynamic pH junction for analysis in human urine samples by capillary electrophoresis-mass spectrometry
    Shengmin Su
    School of Pharmacy, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China
    J Chromatogr A 1216:1490-5. 2009
    ..CE-MS conditions and parameters were also optimized to obtain better performance. The method has been successfully applied in clinical research of rRGD-hirudin...
  101. ncbi A suicide using a homemade carbon monoxide "death machine"
    Joseph A Prahlow
    South Bend Medical Foundation and Indiana University School of Medicine South Bend Center for Medical Education at the University of Notre Dame, South Bend, Indiana 46601, USA
    Am J Forensic Med Pathol 26:177-80. 2005
    ..Presented herein is a case of suicidal CO poisoning in which the CO was produced via a chemical reaction between formic acid and sulfuric acid within a homemade device...

Research Grants26

  1. Alkylammonium Formate Mobile Phase Modifiers for Protein Liquid Chromatography
    NEIL DANIELSON; Fiscal Year: 2009
    ..purpose of our research program is to investigate a new class of room temperature ionic liquids, alkylammonium formates (AAFs), as mobile phase alternatives to organic solvents for liquid chromatography (LC) of proteins...
  2. CONTRACT #N43-CO-95012-616 MONTHS FUNDING -PHASE 1 TOPIC 265 DEVELOPMENT OF SHRN
    Xiao Zeng; Fiscal Year: 2009
    ..on functionally validated (FV) genome-wide human and mouse lentiviral shRNA libraries in arrayed and multiplex formates, and bioinformatics tools for analysis and use of this information in the drug discovery process...
  3. MOLECULAR MECHANISMS OF PROXIMAL TUBULE ION TRANSPORT
    PETER ARONSON; Fiscal Year: 2006
    ..nephrolithiasis, osteoporosis) and NaC1 transport (eg. hypertension, congestive heart failure). ..
  4. Polymerases for Sequencing by Synthesis
    Steven Benner; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  5. DNA Sequencing using Nanopores
    Steven Benner; Fiscal Year: 2007
    ..These will then be targeted against specific sequences extracted from mammalian genomes. [unreadable] [unreadable]..
  6. Iron Homeostasis and its Involvement in C1 Metabolism
    Elizabeth Skovran; Fiscal Year: 2007
    ..extorquens AM1. [unreadable] [unreadable] [unreadable]..
  7. Molecular Basis of Oral Microbial Adhesion
    JANINA LEWIS; Fiscal Year: 2008
    ..intermedia adhesins, which will further knowledge of mediators of the pathogenesis of the bacterium and ultimately lead to identification of potential anti-periodontitis vaccine candidates. ..
  8. COLLAGEN-ANNEXIN INTERACTIONS IN TISSUE MINERALIZATION
    Thorsten Kirsch; Fiscal Year: 2007
    ..abstract_text> ..
  9. REGULATION OF MINERALIZATION IN SKELETAL TISSUES
    Thorsten Kirsch; Fiscal Year: 2009
    ..Therefore, this proposal might provide a novel therapeutic target to prevent pathological mineralization. ..
  10. Chemistry to Improve Human Genomic Array Analysis Architectures
    Steven A Benner; Fiscal Year: 2010
    ..This proposal seeks funds to benchmark the improvements in array performance generated by these new technologies, improve them by a cycle of test and redesign, and provide them to the genomics community. ..
  11. Near Term Development of Reagents and Enzymes for Genome Sequencing
    Steven A Benner; Fiscal Year: 2010
    ..This proposal, from a laboratory with a track record of innovation in structures, reagents, and enzymes to manipulate nucleic acids, is focused on near term development of these to enable NHGRI cost-reduction sequencing goals. ..
  12. Artificial Genetic Systems
    Steven A Benner; Fiscal Year: 2010
    ..Multiplexed PCR is the rate limiting step in many genomics analyses. Our long term, highly ambitious goal is to develop a "synthetic biology", a chemical system capable of Darwinian evolution, based on AEGIS components. ..
  13. Dynamic combinatorial chemistry for nucleic acids
    Steven Benner; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  14. EVOLUTION OF THE RIBONUCLEASE SUPERFAMILY
    Steven Benner; Fiscal Year: 2001
    ....
  15. Transcriptional Nitrogen Regulation in Methanococcus
    JOHN LEIGH; Fiscal Year: 2007
    ..These studies in Archaea have wide importance, as regulatory mechanisms are central to human development and disease. ..
  16. GENOME SEQUENCE AND REGULATION IN M MARIPALUDIS
    JOHN LEIGH; Fiscal Year: 2002
    ..Genes will be identified that either vary in expression with changing conditions, or change in expression after mutagenesis of regulatory genes. ..
  17. Dietary Cysteine:Conceptal Response to Oxidative Stress
    Craig Harris; Fiscal Year: 2002
    ....
  18. Prevotella intermedia: Iron and Virulence
    JANINA LEWIS; Fiscal Year: 2004
    ..intermedia. Since P. intermedia is resistant to many antibiotics alternative methods of preventive measures are needed for this bacterium. ..
  19. ENZYMOLOGY OF ACETOTROPHIC METHANOGENESIS
    JAMES FERRY; Fiscal Year: 2003
    ..The results are expected to contribute not only to a deeper understanding of the acetate fermentation pathway, but more importantly to the broader field of anaerobic microbiology and beyond. ..
  20. Targeted Assisted Combinational Synthesis
    Steven Benner; Fiscal Year: 2004
    ..abstract_text> ..
  21. Osteoblast Derived Pathogenic Factors in Hyp Mice
    Norimoto Yanagawa; Fiscal Year: 2005
    ..abstract_text> ..
  22. NON-STANDARD BASE PAIRS AS BIOMEDICAL RESEARCH TOOLS
    Steven Benner; Fiscal Year: 2004
    ....
  23. Virulence Factor of Porphyromonas gingivalis
    JANINA LEWIS; Fiscal Year: 2005
    ..Lewis' faculty development provides a highly supportive environment for a successful transition to the faculty phase of this award, and bodes well for her rapid development as an independent investigator. ..
  24. TISSUE STRESS VARIABILITY AND STRENGTH IN VERTEBRAL BONE
    Yener Yeni; Fiscal Year: 2006
    ..abstract_text> ..
  25. STRUCTURE OF VIRAL RNA AND ITS ROLE IN ASSEMBLY
    Alexander McPherson; Fiscal Year: 2006
    ..This research is significant because the conformation of the nucleic acid component of no virus is currently known, nor is there any comprehensive structural basis for the processes of viral assembly and disassembly. ..
  26. Transcriptional Integration of Metabolism
    ELTON YOUNG; Fiscal Year: 2007
    ..abstract_text> ..