polymethacrylic acids

Summary

Summary: Poly-2-methylpropenoic acids. Used in the manufacture of methacrylate resins and plastics in the form of pellets and granules, as absorbent for biological materials and as filters; also as biological membranes and as hydrogens. Synonyms: methylacrylate polymer; poly(methylacrylate); acrylic acid methyl ester polymer.

Top Publications

  1. ncbi Fully synthetic polymer vesicles for intracellular delivery of antibodies in live cells
    Irene Canton
    The Krebs Institute, University of Sheffield, Sheffield, UK
    FASEB J 27:98-108. 2013
  2. pmc Zwitterionic carboxybetaine polymer surfaces and their resistance to long-term biofilm formation
    Gang Cheng
    Department of Chemical Engineering, University of Washington, Seattle, WA 98195, USA
    Biomaterials 30:5234-40. 2009
  3. ncbi A pH-dependent colon-targeted oral drug delivery system using methacrylic acid copolymers. II. Manipulation of drug release using Eudragit L100 and Eudragit S100 combinations
    M Z Khan
    Research and Development Division, PLIVA d d, Zagreb, Croatia
    Drug Dev Ind Pharm 26:549-54. 2000
  4. ncbi Influence of NaOCl deproteinization on shear bond strength in function of dentin depth
    Manuel Toledano
    Department of Dental Materials, School of Dentistry, University of Granada, Spain
    Am J Dent 15:252-5. 2002
  5. ncbi pH-sensitive vesicles based on a biocompatible zwitterionic diblock copolymer
    Jianzhong Du
    Department of Chemistry, The University of Sheffield, Brook Hill, Sheffield S3 7HF, United Kingdom
    J Am Chem Soc 127:17982-3. 2005
  6. ncbi Study of water sorption, solubility and modulus of elasticity of light-cured dimethacrylate-based dental resins
    I Sideridou
    Department of Chemistry, Aristotle University of Thessaloniki, GR 54006 Thessaloniki, Hellas, Greece
    Biomaterials 24:655-65. 2003
  7. ncbi Induction of DNA double-strand breaks in primary gingival fibroblasts by exposure to dental resin composites
    Ebru Urcan
    Walther Straub Institute of Pharmacology and Toxicology, Ludwig Maximilians University of Munich, Nussbaumstrasse 26, D 80336 Munich, Germany
    Biomaterials 31:2010-4. 2010
  8. pmc The quest for targeted delivery in colon cancer: mucoadhesive valdecoxib microspheres
    Naveen K Thakral
    Centre for Biomedical Engineering, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, India
    Int J Nanomedicine 6:1057-68. 2011
  9. ncbi A pH-dependent colon targeted oral drug delivery system using methacrylic acid copolymers. I. Manipulation Of drug release using Eudragit L100-55 and Eudragit S100 combinations
    M Z Khan
    Drugs Development Department, Research Institute, PLIVA d d, Prilaz baruna Filipovica 25, 10 000 Zagreb, Croatia
    J Control Release 58:215-22. 1999
  10. ncbi Colonic release and reduced intestinal tissue damage of coated tablets containing naproxen inclusion complex
    Zong Zhu Piao
    National Research Laboratory for Bioavailability Control, College of Pharmacy, Kangwon National University, Chuncheon 200 701, Republic of Korea
    Int J Pharm 350:205-11. 2008

Detail Information

Publications263 found, 100 shown here

  1. ncbi Fully synthetic polymer vesicles for intracellular delivery of antibodies in live cells
    Irene Canton
    The Krebs Institute, University of Sheffield, Sheffield, UK
    FASEB J 27:98-108. 2013
    ..Finally, we demonstrate that intracellular delivery of antibodies can control specific subcellular events, as well as modulate cell activity and proinflammatory processes...
  2. pmc Zwitterionic carboxybetaine polymer surfaces and their resistance to long-term biofilm formation
    Gang Cheng
    Department of Chemical Engineering, University of Washington, Seattle, WA 98195, USA
    Biomaterials 30:5234-40. 2009
    ..The ability of pCBMA coatings to resist non-specific protein adsorption and significantly retard bacterial biofilm formation makes it a very promising material for biomedical and industrial applications...
  3. ncbi A pH-dependent colon-targeted oral drug delivery system using methacrylic acid copolymers. II. Manipulation of drug release using Eudragit L100 and Eudragit S100 combinations
    M Z Khan
    Research and Development Division, PLIVA d d, Zagreb, Croatia
    Drug Dev Ind Pharm 26:549-54. 2000
    ..0 to 7.0. For colon-targeted delivery of drugs, the proposed combination system is superior to tablets coated with either Eudragit L100 or Eudragit S100 alone...
  4. ncbi Influence of NaOCl deproteinization on shear bond strength in function of dentin depth
    Manuel Toledano
    Department of Dental Materials, School of Dentistry, University of Granada, Spain
    Am J Dent 15:252-5. 2002
    ..To determine the influence of NaOCl application on shear bond strengths (SBS) to superficial and deep dentin, using Prime & Bond 2.1...
  5. ncbi pH-sensitive vesicles based on a biocompatible zwitterionic diblock copolymer
    Jianzhong Du
    Department of Chemistry, The University of Sheffield, Brook Hill, Sheffield S3 7HF, United Kingdom
    J Am Chem Soc 127:17982-3. 2005
    ..Gold nanoparticle-decorated vesicles were also obtained by treating the vesicles with HAuCl4, followed by NaBH4...
  6. ncbi Study of water sorption, solubility and modulus of elasticity of light-cured dimethacrylate-based dental resins
    I Sideridou
    Department of Chemistry, Aristotle University of Thessaloniki, GR 54006 Thessaloniki, Hellas, Greece
    Biomaterials 24:655-65. 2003
    ..Gradual replacement of TEGDMA with UDMA or/and Bis-EMA (4) in copolymerization with Bis-GMA resulted in more flexible resins with lower water sorption and higher solubility values, depending on the TEGDMA content...
  7. ncbi Induction of DNA double-strand breaks in primary gingival fibroblasts by exposure to dental resin composites
    Ebru Urcan
    Walther Straub Institute of Pharmacology and Toxicology, Ludwig Maximilians University of Munich, Nussbaumstrasse 26, D 80336 Munich, Germany
    Biomaterials 31:2010-4. 2010
    ..25 and 0.5gamma-H2AX foci/HGF cell. Our results for the first time show that exposure to dental resin monomers can induce DSBs in primary human oral cavity cells, which underscores their genotoxic capacity...
  8. pmc The quest for targeted delivery in colon cancer: mucoadhesive valdecoxib microspheres
    Naveen K Thakral
    Centre for Biomedical Engineering, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, India
    Int J Nanomedicine 6:1057-68. 2011
    ..4 across Caco-2 cell monolayers were conducted. The microspheres were found to exhibit slower and delayed drug release and lower intracellular concentration of valdecoxib...
  9. ncbi A pH-dependent colon targeted oral drug delivery system using methacrylic acid copolymers. I. Manipulation Of drug release using Eudragit L100-55 and Eudragit S100 combinations
    M Z Khan
    Drugs Development Department, Research Institute, PLIVA d d, Prilaz baruna Filipovica 25, 10 000 Zagreb, Croatia
    J Control Release 58:215-22. 1999
    ..For colon targeted delivery of drugs the proposed combination system is superior to tablets coated with either Eudragit L100-55 or Eudragit S100 alone...
  10. ncbi Colonic release and reduced intestinal tissue damage of coated tablets containing naproxen inclusion complex
    Zong Zhu Piao
    National Research Laboratory for Bioavailability Control, College of Pharmacy, Kangwon National University, Chuncheon 200 701, Republic of Korea
    Int J Pharm 350:205-11. 2008
    ....
  11. pmc A critical analysis of the degree of conversion of resin-based luting cements
    Jaime Dutra Noronha Filho
    Department of Restorative Dentistry, School of Dentistry, Federal Fluminense University, Niteroi, RJ, Brazil
    J Appl Oral Sci 18:442-6. 2010
    ..0-mm-thick IPS Empress 2 disc...
  12. ncbi Cisplatin delivery from poly(acrylic acid-co-methyl methacrylate) microparticles
    Xiaoliang Yan
    Department of Biopharmaceutical Sciences, University of Illinois, Chicago, IL, USA
    J Control Release 106:198-208. 2005
    ....
  13. ncbi Naringenin-loaded nanoparticles improve the physicochemical properties and the hepatoprotective effects of naringenin in orally-administered rats with CCl(4)-induced acute liver failure
    Feng Lin Yen
    Faculty of Pharmacy, College of Pharmacy, Kaohsiung Medical University, 100, Shih Chuan 1st Road, Kaohsiung, 807, Taiwan
    Pharm Res 26:893-902. 2009
    ..A novel naringenin-loaded nanoparticles system (NARN) was developed to resolve the restricted bioavailability of naringenin (NAR) and to enhance its hepatoprotective effects in vivo on oral administration...
  14. pmc Folate-decorated nanogels for targeted therapy of ovarian cancer
    Natalia V Nukolova
    Department of Pharmaceutical Sciences and Center for Drug Delivery and Nanomedicine College of Pharmacy, University of Nebraska Medical Center, 985830 Nebraska Medical Center, Omaha, NE 68198 5830, USA
    Biomaterials 32:5417-26. 2011
    ..This reinforces the use of nanogels for the therapy of ovarian and other cancers, where folate receptor (FR) is overexpressed...
  15. ncbi Evaporation of solvent in one-bottle adhesives
    P F Abate
    Department of Dental Materials, School of Dentistry, University of Buenos Aires, Argentina
    J Dent 28:437-40. 2000
    ..To compare the evaporation of vehicles included in different single-bottle adhesives as a function of time...
  16. ncbi Design of a colonic delivery system based on cationic polymethacrylate (Eudragit E100)-mesalamine complexes
    Daniela Alejandra Quinteros
    Departamento de Farmacia Facultad de Ciencias Químicas Universidad Nacional de Córdoba, 5000 Cordoba, Argentina
    Drug Deliv 17:208-13. 2010
    ..In this medium, approximately 60% of M was released in a period of 3 h. Although these results are promising, further studies are still necessary to evaluate the possible in vitro/in vivo correlations...
  17. pmc Cisplatin-loaded core cross-linked micelles: comparative pharmacokinetics, antitumor activity, and toxicity in mice
    Hardeep S Oberoi
    Department of Pharmaceutical Sciences and Center for Drug Delivery and Nanomedicine, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198 5830, USA
    Int J Nanomedicine 7:2557-71. 2012
    ..Overall, the study supports the fundamental possibility of improving the potential of platinum therapy using polymer micelle-based drug delivery...
  18. ncbi Curing depth of a resin-modified glass ionomer and two resin-based luting agents
    Ricardo Massao Sigemori
    Department of Restorative Dentistry, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil
    Oper Dent 30:185-9. 2005
    ..Within the medium third, there were no significant differences among luting materials. However, within the deep third, Rely X presented the highest values. KHN values of resin-based luting agents decreased remarkably as depth increased...
  19. ncbi Statistical optimization of indomethacin pellets coated with pH-dependent methacrylic polymers for possible colonic drug delivery
    A Akhgari
    School of Pharmacy and Pharmaceutical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
    Int J Pharm 305:22-30. 2005
    ..The optimized formulation produced dissolution profiles that were close to predicted values...
  20. pmc Eudragit S100 entrapped insulin microspheres for oral delivery
    Deepti Jain
    Department of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, Formerly College of Pharmacy, University of Delhi, Pushp Vihar, Sector III, New Delhi 110017, India
    AAPS PharmSciTech 6:E100-7. 2005
    ..75%. Thus, our results indicate that Eudragit S100 microspheres on oral administration can protect insulin from proteolytic degradation in the gastrointestinal tract and produce hypoglycemic effect...
  21. ncbi Design of a potential colonic drug delivery system of mesalamine
    Mukesh C Gohel
    Department of Pharmaceutics and Pharmaceutical Technology, L M College of Pharmacy, Ahmedabad, India
    Pharm Dev Technol 13:447-56. 2008
    ..4 and complete drug release was obtained thereafter within 2 hr. A short-term dissolution stability study demonstrated statistical insignificant difference in drug release...
  22. pmc Eudragit-coated pectin microspheres of 5-fluorouracil for colon targeting
    Amol Paharia
    Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar, India
    AAPS PharmSciTech 8:12. 2007
    ..4. It is concluded from the present investigation that Eudragit-coated pectin microspheres are promising controlled release carriers for colon-targeted delivery of FU...
  23. ncbi The effect of curing light and chemical catalyst on the degree of conversion of two dual cured resin luting cements
    Eduardo José Souza-Junior
    Piracicaba Dental School, Department of Restorative Dentistry, University of Campinas UNICAMP, Piracicaba, SP, Brazil
    Lasers Med Sci 27:145-51. 2012
    ..To obtain a satisfactory degree of conversion, Panavia F luting cement should be used with ED Primer and cured with halogen light...
  24. ncbi Development and characterization of colon specific drug delivery system bearing 5-ASA and Camylofine dihydrochloride for the treatment of ulcerative colitis
    Rupal Dubey
    Pharmaceutics Research Projects Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour Central University, Sagar, MP, India
    J Drug Target 18:589-601. 2010
    ..It is concluded that orally administered microspheres of both drugs can be used together for the specific delivery of drug to the colon and reduce symptoms of ulcerative colitis...
  25. ncbi Eudragit-S, Eudragit-L and cellulose acetate phthalate coated polysaccharide tablets for colonic targeted delivery of azathioprine
    Nandkishor Kotagale
    Smt Kishoritai Bhoyar College of Pharmacy, Nagpur, India
    Pharm Dev Technol 15:431-7. 2010
    ..Thus inulin containing ES, EL and CAP (1:1:1) polymer-coated formulation system can be used for the targeted delivery of azathioprine with desired release pattern...
  26. ncbi Development of pH-sensitive pectinate/alginate microspheres for colon drug delivery
    Fu Yin Hsu
    Department of Life Sciences, National Taiwan Ocean University, Keelung, Taiwan, ROC
    J Mater Sci Mater Med 24:317-23. 2013
    ..0. Drug release from the Eudragit S100-coated PAMs was best described by the Higuchi's square root model. From these results, it was concluded that Eudragit S100-coated PAMs are a potential carrier for delivery of cisplatin to the colon...
  27. ncbi Improved drug delivery to the lower intestinal tract with tablets compression-coated with enteric/nonenteric polymer powder blends
    Soravoot Rujivipat
    College of Pharmacy, Freie Universitat Berlin, Berlin, Germany
    Eur J Pharm Biopharm 76:486-92. 2010
    ....
  28. ncbi Predictable pulsatile release of tramadol hydrochloride for chronotherapeutics of arthritis
    Chandu Dabhi
    Department of Pharmaceutics, R C Patel Institute of Pharmaceutical Education and Research, Shirpur 425405, District Dhule M S, India
    Drug Deliv 17:273-81. 2010
    ..The results showed the capability of the system in achieving pulsatile release for a programmable period of time and pH-dependent release to attain colon-targeted delivery...
  29. ncbi Effect of sodium sulfinate salts on the polymerization characteristics of dual-cured resin cement systems exposed to attenuated light-activation
    Cesar A G Arrais
    Department of Operative Dentistry, School of Dentistry, University of Guarulhos, Guarulhos, Sao Paulo, Brazil
    J Dent 37:219-27. 2009
    ....
  30. ncbi Degradation of polymeric restorative materials subjected to a high caries challenge
    Márcio A P Borges
    Brazilian Navy, Navy Central Clinic, Rio de Janeiro, RJ, Brazil
    Dent Mater 27:244-52. 2011
    ..The aim of this study was to evaluate the degradation of different resin filling materials after a caries challenge, by high performance liquid chromatography (HPLC) and contact angle (θ) measurement...
  31. ncbi Pulsatile drug delivery to ileo-colonic segments by structured incorporation of disintegrants in pH-responsive polymer coatings
    R C A Schellekens
    Department of Clinical and Hospital Pharmacy, University Medical Center Groningen, The Netherlands
    J Control Release 132:91-8. 2008
    ..In a proof-of-concept in vivo study it was shown that the newly developed coating enables pulsatile delivery of the content to the lower parts of the intestines...
  32. ncbi Differential effect of in vitro degradation on resin-dentin bonds produced by self-etch versus total-etch adhesives
    Manuel Toledano
    Department of Dental Materials, School of Dentistry, University of Granada Spain, Granada, Spain
    J Biomed Mater Res A 77:128-35. 2006
    ..To evaluate the effect of an in vitro challenge (NaOCl immersion) on microtensile bond strength (MTBS) of five adhesive systems to dentin...
  33. ncbi The importance of dentin collagen fibrils on the marginal sealing of adhesive restorations
    Juliana Raposo Souto Maior
    Federal University of Pernambuco, Recife, PE, Brazil
    Oper Dent 32:261-5. 2007
    ..0345) and C2 (p = 0.0029). The results showed that the collagen fibrils were not necessary for adhesion, and their removal positively influenced the marginal sealing of Prime&Bond NT and One Coat Bond...
  34. ncbi Bond failure at dentin-composite interfaces with 'single-bottle' adhesives
    P R Walshaw
    Restorative Dentistry, Faculty of Dentistry, University of Toronto, 124 Edward Street, Toronto, Ontario, Canada
    J Dent 31:117-25. 2003
    ..Resulting fractured test specimens were examined under SEM to determine differences in micromorphology, which might account for the respective intK(1c) results...
  35. pmc Wetting ability of an acetone/based etch&rinse adhesive after NaOCl-treatment
    Fatima S Aguilera
    Department of Dental Materials, School of Dentistry, Campus de Cartuja 18071, University of Granada, Spain
    Med Oral Patol Oral Cir Bucal 17:e644-8. 2012
    ..to evaluate the effect of sodium hypochlorite (NaOCl) treatment on surface dentin roughness (Ra) and contact angle (CA) when using Prime&Bond NT adhesive (PB NT)...
  36. ncbi Components of dentinal adhesives modulate heat shock protein 72 expression in heat-stressed THP-1 human monocytes at sublethal concentrations
    M Noda
    Department of Oral Health Science, Graduate School of Dental Medicine, Hokkaido University Graduate School of Dental Medicine, Kita 13, Nishi 7, Kita ku, Sapporo 060 8586, Japan
    J Dent Res 81:265-9. 2002
    ..The results of the current study suggest that components released from dental resin could modulate the HSP stress response without altering cellular metabolic activity...
  37. ncbi Additive effects of TEGDMA and hydrogenperoxide on the cellular glutathione content of human gingival fibroblasts
    Joachim Volk
    Department of Conservative Dentistry and Periodontology, Medical University Hannover, Hannover, Germany
    Dent Mater 23:921-6. 2007
    ....
  38. ncbi Apoptosis induced by the monomers HEMA and TEGDMA involves formation of ROS and differential activation of the MAP-kinases p38, JNK and ERK
    Jan T Samuelsen
    NIOM Nordic Institute of Dental Materials, PO Box 70, N 1305 Haslum, Norway
    Dent Mater 23:34-9. 2007
    ..The aim of the present study was to elucidate possible signaling pathways involved in apoptosis following exposure to HEMA or TEGDMA in a salivary gland cell line...
  39. ncbi Elution of monomers from two conventional dental composite materials
    Olga Polydorou
    Department of Operative Dentistry and Periodontology, Dental School and Hospital, Albert Ludwigs University Freiburg, Hugstetter Strasse 55, 79106 Freiburg i Br, Germany
    Dent Mater 23:1535-41. 2007
    ..The aim of this study was to determine the elution of monomers of two conventional resin composite materials after different polymerization and storage times...
  40. ncbi Sub-compartmentalization of the gastrointestinal (GI) immune system determined with microbeads that differ in release properties
    Richard Ivan Cronkhite
    Department of Molecular Genetics, University of Cincinnati, Cincinnati, OH 45267, USA
    Vaccine 22:2106-15. 2004
    ..Acute immunization was best able to potentiate isotypes influenced by type 1 T helper cells (T(h)1) and a sequential segregated immunization protocol allowed the targeting of T(h)1-like memory responses...
  41. ncbi Inhibition of TEGDMA and HEMA-induced genotoxicity and cell cycle arrest by N-acetylcysteine
    H Schweikl
    Department of Operative Dentistry and Periodontology, University of Regensburg, D 93042 Regensburg, Germany
    Dent Mater 23:688-95. 2007
    ..In addition, we analyzed the effects of TEGDMA and HEMA on the normal cell cycle in the presence of NAC...
  42. ncbi Involvement of oxidative stress in mutagenicity and apoptosis caused by dental resin monomers in cell cultures
    Dong Hee Lee
    Department of Dental Biomaterials Science and Dental Research Institute, College of Dentistry, Seoul National University, 28 Yeonkun dong, ChongRo Ku, Seoul 110 749, South Korea
    Dent Mater 22:1086-92. 2006
    ..This investigation studied the possibility that apoptosis as well as mutagenicity induced by resin monomers are mediated by oxidative stress...
  43. ncbi ROS formation and glutathione levels in human oral fibroblasts exposed to TEGDMA and camphorquinone
    J Engelmann
    Department of Conservative Dentistry and Periodontology, Medical University Hannover, D 30625 Hannover, Germany
    J Biomed Mater Res B Appl Biomater 75:272-6. 2005
    ..As a consequence, TEGDMA and CQ released into an aqueous environment from resinous materials might interact, thus generating significant cytotoxic effects even at low concentrations...
  44. ncbi Sublethal, 2-week exposures of dental material components alter TNF-alpha secretion of THP-1 monocytes
    Mamoru Noda
    Department of Oral Health Sciences, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan
    Dent Mater 19:101-5. 2003
    ..The current study significantly extended exposure times of monocytes to the components over times published in previous studies. These exposure times approached the estimated average life span of monocytes in the bloodstream...
  45. ncbi Effects of adhesive composition on microtensile bond strength to human dentin
    M F Nunes
    Department of Operative Dentistry, University of North Carolina School of Dentistry, Chapel Hill 27599-7450, USA
    Am J Dent 14:340-3. 2001
    ..The ethanol-based adhesive SB had a significantly higher mean bond strength than either the nonvolatile solvent-based OC or the acetone-based NT...
  46. ncbi Influence of resin monomers on growth of oral streptococci
    Y Takahashi
    Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, 1 8 Yamadaoka, Suita, Osaka 565 0871, Japan
    J Dent Res 83:302-6. 2004
    ....
  47. ncbi Shear bond strength of four filled dentin bonding systems
    J R Gallo
    LSU School of Dentistry, 1100 Florida Ave, Box 137, New Orleans, LA 70124, USA
    Oper Dent 26:44-7. 2001
    ..The data were subjected to One-Factor ANOVA and Newman-Kuels post-hoc tests. Statistical analysis revealed that One Coat Bond had significantly greater shear bond strength than all other materials tested...
  48. ncbi Influence of pH and time on organic substance release from a model dental composite: a fluorescence spectrophotometry and gas chromatography/mass spectrometry analysis
    Ulf Ortengren
    Department of Prosthetic Dentistry Dental Materials Science, Faculty of Odontology, Sahlgrenska Academy at Goteborg University, SE 405 30 Goteborg, Sweden
    Eur J Oral Sci 112:530-7. 2004
    ..Critical combinations of time and pH allowed the elution of several organic substances, predominantly methacrylic acid, triethylene glycol dimethacrylate and hydroquinone, from the model resin composite, Z-100...
  49. ncbi Resistance of ten contemporary adhesives to resin-dentine bond degradation
    Raquel Osorio
    Department of Dental Materials, Campus de Cartuja s n, School of Dentistry, University of Granada, Granada, Spain
    J Dent 36:163-9. 2008
    ..To evaluate resin-dentine bond degradation after 1 year of water storage...
  50. ncbi Substances released from dental resin composites and glass ionomer cements
    W Geurtsen
    Department of Conservative Dentistry and Periodontology, Medical University Hannover, Germany
    Eur J Oral Sci 106:687-95. 1998
    ..Therefore, further studies are necessary to determine quality and quantity of substances segregated from resin composites and GICs...
  51. ncbi Stability of bisphenol A, triethylene-glycol dimethacrylate, and bisphenol A dimethacrylate in whole saliva
    Jane C Atkinson
    Clinical Research Core, National Institute of Dental and Craniofacial Research NIH, Bethesda, MD, USA
    Dent Mater 18:128-35. 2002
    ..This study investigated the stability of compounds of dental sealant materials in a salivary matrix...
  52. ncbi Salivary esterase activity and its association with the biodegradation of dental composites
    Y Finer
    Restorative Discipline, aculty of Dentistry, University of Toronto, Toronto, ON, Canada
    J Dent Res 83:22-6. 2004
    ..Saliva was found to contain both hydrolase activities at levels that could degrade composite resins. PMSF inhibited the composite degradation, indicating a material hydrolysis mechanism similar to the enzymes' common function...
  53. ncbi Antioxidative vitamins decrease cytotoxicity of HEMA and TEGDMA in cultured cell lines
    U I Walther
    Walther Straub Institut für Pharmakologie und Toxikologie der Ludwig Maximilians Universität, Nussbaumstr 26, 80336 Munchen, Germany
    Arch Oral Biol 49:125-31. 2004
    ....
  54. ncbi Cytotoxicity of three dentin bonding agents on human dental pulp cells
    Ruey Song Chen
    School of Dentistry, College of Medicine, National Taiwan University, and National Taiwan University Hospital, Taipei, Taiwan, ROC
    J Dent 31:223-9. 2003
    ..However, DBA may exert potentially harmful effects to the dental pulp. In the present study, differential cytotoxicity of three DBA (Syntac Sprint, SP; Prime and Bond 2.1, PB; and Single Bond, SB) on the pulp cells was tested...
  55. ncbi TEGDMA-induced oxidative DNA damage and activation of ATM and MAP kinases
    Alexander Eckhardt
    Department of Operative Dentistry and Periodontology, University of Regensburg, Regensburg, Germany
    Biomaterials 30:2006-14. 2009
    ..Signaling through ATM indicates oxidative DNA damage and the activation of MAPK pathways indicates oxidative stress-induced regulation of cell survival and apoptosis...
  56. ncbi Estrogenicity of fissure sealants and adhesive resins determined by reporter gene assay
    H Tarumi
    Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, Suita, Japan
    J Dent Res 79:1838-43. 2000
    ..This suggests that the estrogenicity of the two proprietary sealants was associated with BPA-DMA rather than with BPA...
  57. ncbi HPLC analysis of eluted monomers from two composite resins cured with LED and halogen curing lights
    Masumeh Hasani Tabatabaee
    Department of Restorative Dentistry, Faculty of Dentistry, Tehran University of Medical Sciences and Dental Research Center, Tehran, Iran
    J Biomed Mater Res B Appl Biomater 88:191-6. 2009
    ....
  58. ncbi Inhibition of cytokine and surface antigen expression in LPS-stimulated murine macrophages by triethylene glycol dimethacrylate
    Alexander Eckhardt
    Department of Operative Dentistry and Periodontology, University of Regensburg, Germany
    Biomaterials 30:1665-74. 2009
    ..Thus, the ability of macrophages to induce an appropriate immune response is inhibited by TEGDMA which reduces cytokine production and expression of surface antigens...
  59. ncbi Elution of TEGDMA and BisGMA from a resin and a resin composite cured with halogen or plasma light
    E C Munksgaard
    Department of Dental Materials, School of Dentistry, University of Copenhagen, Denmark
    Eur J Oral Sci 108:341-5. 2000
    ..It was concluded that the plasma arc light curing unit did not provide optimal cure when used as recommended by the manufacturer...
  60. ncbi Pattern of cell death after in vitro exposure to GDMA, TEGDMA, HEMA and two compomer extracts
    Rune Becher
    Noraic Institute of Dental Materials, Haslum, Norway
    Dent Mater 22:630-40. 2006
    ....
  61. ncbi Effect of a sodium hypochlorite gel on dentin bonding
    J Perdigao
    Division of Operative Dentistry, University of Minnesota, Minneapolis, MN, USA
    Dent Mater 16:311-23. 2000
    ..To substantiate this hypothetical insignificance of the HL, sodium hypochlorite (NaOCl) has been used to remove collagen from etched dentin prior to bonding...
  62. ncbi Adhesion between collagen depleted dentin and dentin adhesives
    N Inai
    Dept Operative Dentistry, Tokyo Medical and Dental University, Faculty of Dentistry, Bunkyo ku, Japan
    Am J Dent 11:123-7. 1998
    ..To determine the influence of sodium hypochlorite treatment of dentin on shear bond strength and morphology...
  63. ncbi Biocompatibility of resin-modified filling materials
    W Geurtsen
    Department of Conservative Dentistry and Periodontology, Medical University Hannover, Germany
    Crit Rev Oral Biol Med 11:333-55. 2000
    ..Therefore, it is critical, both for our patients and for the profession, that the biological effects of resin-based filling materials be clarified in the near future...
  64. ncbi The effect of triethylene glycol dimethacrylate on the cell cycle of mammalian cells
    Helmut Schweikl
    Department of Operative Dentistry and Periodontology, University of Regensburg, D 93042 Regensburg, Germany
    Biomaterials 26:4111-8. 2005
    ..From these results, we conclude that TEGDMA may influence physiological processes like cell growth and differentiation of human pulp cells in vivo...
  65. ncbi Triethylene glycol dimethacrylate induces large deletions in the hprt gene of V79 cells
    H Schweikl
    Department of Operative Dentistry and Periodontology, University of Regensburg, D 93042, Regensburg, Germany
    Mutat Res 438:71-8. 1999
    ..Therefore, we conclude by analogy that the induction of large DNA sequence deletions as shown here with the reactive dimethacrylate, triethylene glycol dimethacrylate, is probably common for acrylates and methacrylates...
  66. ncbi Preparation and in vitro/in vivo evaluation of gliclazide loaded Eudragit nanoparticles as a sustained release carriers
    Padma V Devarajan
    Pharmaceutical Division, Institute of Chemical Technology, University of Mumbai, Matunga, Mumbai, India
    Drug Dev Ind Pharm 33:101-11. 2007
    ..The developed Eudragit (L100 and RSPO) NP could reduce dose frequency, decrease side effects, and improve patient compliance...
  67. ncbi Elution parameters and HPLC-detection of single components from resin composite
    M Pelka
    Policlinic for Operative Dentistry and Periodontology, University of Erlangen Nurnberg, Germany
    Clin Oral Investig 3:194-200. 1999
    ..Within acid conditions a hydrolytic disintegration of the ester bonding of the monomers could be observed. Methacrylic acid--a substance with allergenic potential--could be detected...
  68. ncbi Evaluation of Eudragit-coated chitosan microparticles as an oral immune delivery system
    Mika Hori
    Department of Drug Delivery Research, Hoshi University, 2 4 41 Ebara, Shinagawa ku, Tokyo 142 8501, Japan
    Int J Pharm 297:223-34. 2005
    ..OVA-specific IgA was induced significantly more efficiently by ER-Chi-OVA than the others. These suggested that ER-Chi-OVA should be possibly useful to induce an intestinal mucosal immune response...
  69. ncbi Metabolism of TEGDMA and HEMA in human cells
    Jürgen Durner
    Institute of Clinical Chemistry, Ludwig Maximilians University of Munich, Germany
    Biomaterials 31:818-23. 2010
    ..Therefore the epoxide pathway with formation of the epoxy-intermediate 2,3-epoxymethacrylic acid is the main route of metabolisation of HEMA and TEGDMA...
  70. ncbi Eudragit S-100 entrapped chitosan microspheres of valdecoxib for colon cancer
    Naveen K Thakral
    Centre for Biomedical Engineering, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, 110016, India
    J Mater Sci Mater Med 21:2691-9. 2010
    ..4 for 30 min, when applied to mucosal surface of freshly excised goat colon, showed good mucoadhesion. The drug release at pH 7.4 and good mucoadhesive property of the microspheres make the system ideal for colonic delivery...
  71. ncbi Insulin loaded eudragit L100 microspheres for oral delivery: preliminary in vitro studies
    Deepti Jain
    Department of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, Formerly College of Pharmacy University of Delhi Pushp Vihar, Sector III, New Delhi 110 017, India
    J Biomater Appl 21:195-211. 2006
    ..Scanning electron microscopy of PVA stabilized microspheres demonstrated spherical particles with smooth surface and laser diffractometry revealed a mean particle size (V(m)) of 59.11 30 m...
  72. ncbi High-Q polymer-coated microspheres for immunosensing applications
    S Soria
    IFAC CNR, NelloCarrara Institute of Applied Physics, Via Madonna del Piano 10, 50019 Sesto Fiorentino, Florence, Italy
    Opt Express 17:14694-9. 2009
    ..This functionalizing process of the microresonator constitutes a promising step towards the achievement of an ultra sensitive immunosensor...
  73. ncbi Genetic and cellular toxicology of dental resin monomers
    H Schweikl
    Department of Operative Dentistry and Periodontology, University of Regensburg, D 93042 Regensburg, Germany
    J Dent Res 85:870-7. 2006
    ..Pathways regulating cellular homeostasis, dentinogenesis, or tissue repair may be modified by monomers at concentrations well below those which cause acute cytotoxicity...
  74. ncbi Genotoxicity and cytotoxicity of dental materials in human lymphocytes as assessed by the single cell microgel electrophoresis (comet) assay
    Norbert H Kleinsasser
    Klinisch experimentelle Onkologie, Department of Otolaryngology Head and Neck Surgery, Ludwig Maximilians University Munich, Munich, Germany
    J Dent 32:229-34. 2004
    ..Whereas the cytotoxic potential of some components has been clearly documented, possible genotoxicity in human target cells demands further investigation...
  75. ncbi "No-bottle" vs "multi-bottle" dentin adhesives--a microtensile bond strength and morphological study
    R Frankenberger
    Policlinic for Operative Dentistry and Periodontology, University of Erlangen-Nuremberg, Glueckstrasse 11, D-91054 Erlangen, Germany
    Dent Mater 17:373-80. 2001
    ..When applied in multiple coats, Prompt L-Pop results in bond strengths that are not statistically different from those of Prime&Bond NT, a total-etch adhesive...
  76. ncbi Influence of restorative technique, beveling, and aging on composite bonding to sectioned incisal edges
    Fábio Herrmann Coelho-de-Souza
    School of Dentistry, Lutheran University of Brazil, Cachoeira do Sul, RS, Brazil
    J Adhes Dent 10:113-7. 2008
    ..The aim of this study was to evaluate the effect of material technique, bevel placement, and aging on the fracture resistance of composite restorations bonded to sectioned incisal edges...
  77. ncbi Influence of light-activated and auto- and dual-polymerizing adhesive systems on bond strength of indirect composite resin to dentin
    Maria Jose Lorena de Menezes
    Department of Restorative Dentistry, Piracicaba School of Dentistry, State University of Campinas, SP, Brazil
    J Prosthet Dent 96:115-21. 2006
    ..An inadequate choice may compromise the success of indirect restorations...
  78. ncbi Effect of chlorhexidine application on microtensile bond strength to dentin
    Carlos Jose Soares
    Operative Dentistry and Dental Materials Department Dental School, Federal University of Uberlandia, Minas Gerais, Brazil
    Oper Dent 33:183-8. 2008
    ..52; 2: 21.62+/-2.5; 1: 21.28+/-3.17; 3: 19.62+/-2.05; 4: 19.55+/-2.34. The use of chlorhexidine at concentrations of 0.12% and 2% before, after or associated with acid etching did not significantly affect the microTBS values to dentin...
  79. ncbi The effects of cavity size and incremental technique on micro-tensile bond strength of resin composite in Class I cavities
    Zhengdi He
    Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, 1 5 45, Yushima, Tokyo 113 8549, Japan
    Dent Mater 23:533-8. 2007
    ..The purpose of this study was to investigate if incremental-filling technique and cavity size would affect the bond strength of resin composite...
  80. pmc Degree of cure and fracture properties of experimental acid-resin modified composites under wet and dry conditions
    Francisco Lopez-Suevos
    American Dental Association Foundation, Paffenbarger Research Center, NIST, Gaithersburg, MD 20899, USA
    Dent Mater 24:778-85. 2008
    ..Evaluate the effects of core structure and storage conditions on the mechanical properties of acid-resin modified composites and a control material by three point bending and conversion measurements 15min and 24h after curing...
  81. ncbi Fatigue resistance of the bond of a glass-infiltrated alumina ceramic to human dentin
    Paolo Baldissara
    Department of Oral Science, University of Bologna, Italy
    J Adhes Dent 8:97-104. 2006
    ..To evaluate the fatigue resistance of the bond between dentin and glass-infiltrated alumina ceramic, using different luting protocols...
  82. ncbi Bond strength of total-etch and self-etch dentin adhesive systems on peripheral and central dentinal tissue: a microtensile bond strength test
    C Yesilyurt
    Department of Restorative Dentistry, Faculty of Dentistry, Karadeniz Technical University, Trabzon, Turkey
    J Contemp Dent Pract 7:26-36. 2006
    ..In addition the interface between the adhesive resins and dentin was examined using scanning electron microscopy (SEM)...
  83. ncbi Effect of cyclic loading on the microtensile bond strengths of total-etch and self-etch adhesives
    Manuel Toledano
    Faculty of Dentistry, University of Granada, Granada, Spain
    Oper Dent 31:25-32. 2006
    ..To evaluate the effect of mechanical loading on the microtensile bond strength (MTBS) of five adhesive systems to dentin...
  84. ncbi Effect of surface conditioning and restorative material on the shear bond strength and resin-dentin interface of a new one-bottle nanofilled adhesive
    Michelle C Sunico
    Department of Operative Dentistry, School of Dentistry at Niigata, The Nippon Dental University, 1 8 Hamauracho, Niigata 951 8580, Japan
    Dent Mater 18:535-42. 2002
    ....
  85. ncbi Microleakage of different amalgams bonded with dual cure resin cements
    R Lombard
    Operative Dentistry, University of Limpopo Medunsa Campus, South Africa
    SADJ 62:056, 058-61. 2007
    ..To reduce microleakage in high-copper amalgam restorations, bonding of amalgam was introduced...
  86. ncbi Bonding agent is a decisive factor in determining the marginal leakage of dental composites subjected to thermal cycling: an in vitro study
    M Mathew
    Yenepoya Dental College, Kodial Bail, Mangalore
    J Oral Rehabil 28:68-77. 2001
    ..1 and Chitra/Chitrabond 1.0). Thermal cycling during in vitro studies was found to provide a more appropriate representation of the adhesive behaviour of the composite in clinical situations...
  87. ncbi Dynamic mechanical analysis of storage modulus development in light-activated polymer matrix composites
    Ronald L Sakaguchi
    Department of Biomaterials and Biomechanics, Oregon Health and Science University, 611 SW Campus Dr, SD 503, Portland, OR 97201, USA
    Dent Mater 18:197-202. 2002
    ..The goal of this study was to evaluate the potential for using dynamic mechanical analysis of tubular geometry in a three-point flexure fixture for monitoring the storage modulus development of a light-activated polymer matrix composite...
  88. ncbi Tensile bond strength and flexural modulus of resin cements--influence on the fracture resistance of teeth restored with ceramic inlays
    Luciano de Vargas Habekost
    Luciano de Vargas Habekost, MS, School of Dentistry, Federal University of Pelotas, Pelotas, RS, Brazil
    Oper Dent 32:488-95. 2007
    ..This in vitro study tested tensile bond strength to enamel and dentin and the flexural modulus of three resin cements. It also determined the influence of these properties on the fracture resistance of teeth restored with ceramic inlays...
  89. ncbi Bonding strength to two different surfaces of dentin under simulated pulpal pressure
    S Belli
    Department of Operative Dentistry, , School of Dentistry, Campus, Konya, Turkey
    J Adhes Dent 3:145-52. 2001
    ....
  90. ncbi The influence of dentin and/or metal surface treatment on the retention of cemented crowns in teeth with an increased taper
    Raphael Pilo
    Department of Oral Rehabilitation, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel
    Dent Mater 24:1058-64. 2008
    ..To evaluate the effect of dentin and/or metal surface treatments on retention of cast crowns cemented to preparations with compromised retention...
  91. ncbi Microleakage in full-crown all-ceramic restorations: influence of internal surface treatment, silane application, alumina system, and substrate
    Angela Brys Osório
    Operative Dentistry Department, School of Dentistry, Federal University of Pelotas, Rio Grande do Sul, Brazil
    Int J Prosthodont 20:123-4. 2007
    ..Statistical analysis (P < .05) showed higher leakage in dentin margins compared to enamel. In enamel, Procera showed greater leakage compared to In-Ceram. Generally, lower microleakage was observed for the AO plus silane treatment...
  92. ncbi Surface conditioning of a composite used for inlay/onlay restorations: effect on muTBS to resin cement
    Luiz Felipe Valandro
    Department of Restorative Dentistry, School of Dentistry, Federal University of Santa Maria, Brazil
    J Adhes Dent 9:495-8. 2007
    ..To assess the effect of the composite surface conditioning on the microtensile bond strength of a resin cement to a composite used for inlay/onlay restorations...
  93. ncbi Bond strength of self-etching primers to enamel and dentin of primary teeth
    F G Agostini
    Department of Pediatric Dentistry, University of Texas Health Science Center at Houston Dental Branch, USA
    Pediatr Dent 23:481-6. 2001
    ..5 MPa). CONCLUSIONS: The results of this in vitro study show that the four adhesive systems tested bonded effectively to enamel of primary teeth, but only CSE achieved adequate bond strengths to dentin of primary teeth...
  94. ncbi The extent to which resin can infiltrate dentin by acetone-based adhesives
    M Hashimoto
    Department of Operative Dentistry and Endodontics, Iwate Medical University, School of Dentistry, Morioka, Japan
    J Dent Res 81:74-8. 2002
    ..Based on those findings, it was suggested that the integrity between the bonding resin and the top of the hybrid layer played a major role in bond strength...
  95. ncbi Shear bond strength between feldspathic CAD/CAM ceramic and human dentine for two adhesive cements
    Lorenzo Graiff
    Department of Restorative Dentistry, University of Padova, Institute of Clinical Dentistry, Padova, Italy
    J Prosthodont 17:294-9. 2008
    ..In addition, the effect of a silane coupling agent on bond strength was evaluated...
  96. ncbi Polymerization shrinkage of experimental short glass fiber-reinforced composite with semi-inter penetrating polymer network matrix
    Sufyan Garoushi
    Department of Prosthetic Dentistry and Biomaterials Science, Institute of Dentistry, University of Turku, Turku, Finland
    Dent Mater 24:211-5. 2008
    ..The aim of this study was to determine the magnitude of short fiber-reinforced composite resin, with a semi-IPN-polymer matrix, on polymerization resin shrinkage-strain, shrinkage stress and marginal microleakage of the restoration...
  97. ncbi Comparison of the flexural strength of five adhesive resin cements
    Larry L Pace
    Private Practice, Dallas, TX, USA
    J Prosthodont 16:18-24. 2007
    ..The increased use of adhesive resin cements in bonded prosthetic restorations has led to restorations debonding under function...
  98. ncbi Long-term TEM analysis of the nanoleakage patterns in resin-dentin interfaces produced by different bonding strategies
    Andre F Reis
    Department of Restorative Dentistry, Division of Operative Dentistry, Piracicaba School of Dentistry, University of Campinas, Av Limeira 901, Piracicaba, CEP 13414 903, SP, Brazil
    Dent Mater 23:1164-72. 2007
    ..The aim of this study was to evaluate the ability of etch-and-rinse and self-etching adhesive systems to prevent time- and water-induced nanoleakage in resin-dentin interfaces over a 6-month storage period...
  99. ncbi Bonding of dual-curing resin cements to dentin
    Erik Asmussen
    Department of Dental Materials, School of Dentistry, University of Copenhagen, Copenhagen, Denmark
    J Adhes Dent 8:299-304. 2006
    ....
  100. ncbi Comparative in vivo and in vitro investigation of interfacial bond variability
    M Hannig
    Department of Operative Dentistry and Periodontology, University of Freiburg, Hugstetter Strasse 55, D-79106 Freiburg, Germany
    Oper Dent 26:3-11. 2001
    ..It was concluded that achievement of a completely gap-free internal adaptation between restorative material and dentin in totally bonded composite resin restorations is difficult to predict under in vivo as well as in vitro conditions...
  101. ncbi A comparison of microtensile bond strengths of several dentin bonding systems to primary and permanent dentin
    M F Burrow
    School of Dental Science, The University of Melbourne, 711 Elizabeth Street, Melbourne, Victoria 3000, Australia
    Dent Mater 18:239-45. 2002
    ..The bonded interfaces were also observed using field emission electron microscopy(FE-SEM)...

Research Grants28

  1. REDUCTION OF COMPOSITE POLYMERIZATION CONTRACTION STRESS
    RONALD SAKAGUCHI; Fiscal Year: 2002
    ..Clinically significant reductions in contraction strain and stress will be produced which will improve the function and longevity of resin composite restorations. ..
  2. EVALUATION OF A CIGARETTE SUBSTITUTE
    John Hughes; Fiscal Year: 2001
    ..We believe it imperative to begin studying these substitutes so that, unlike low-tar/low nicotine cigarettes, we will know whether their introduction is good or bad for public health. ..
  3. Assessment of Tissue Response to Stress
    Joan Sanders; Fiscal Year: 2006
    ..this technology could be applied to other areas of rehabilitation, for example, shoe design for patients with insensate feet, cushion design for wheelchair users, and mattress design for bedridden patients [unreadable] [unreadable]..
  4. Natural History of Attempts to Stop Smoking
    John R Hughes; Fiscal Year: 2010
    ....
  5. Skin Adaptation to Mechanical Stress
    Joan Sanders; Fiscal Year: 2006
    ..By understanding the process of skin adaptation (natural skin strengthening) at both a cellular and molecular level, therapies to encourage skin adaptation before breakdown occurs can be intelligently pursued. ..
  6. Engineered Outer Membrane Vesicles as DNA Vaccine Delivery Vehicles
    David Putnam; Fiscal Year: 2007
    ..Validation of the hypothesis will support the future engineering of OMVs with more intricate characteristics, such as cell specific ligands, fusogenic proteins and conformational protein adjuvants. [unreadable] [unreadable] [unreadable]..
  7. Molecular/Mechanical Imaging of Dentin Bonding Substrate
    Yong Wang; Fiscal Year: 2007
    ..Results from this work will provide critical, new insight into failure mechanisms at the dentin/adhesive interface; failure that can ultimately lead to premature breakdown of the composite restoration. ..
  8. Gradual vs Abrupt Cessation Treatment for Smoking
    John Hughes; Fiscal Year: 2007
    ..This study will be the first large, systematic test of gradual vs. abrupt cessation. ..
  9. INTERFACE MECHANICS, MATERIALS AND TISSUE RESPONSE
    Joan Sanders; Fiscal Year: 2007
    ..The development of methods to predict and overcome the detrimental effects of residual limb shape change and ultimately prevent soft-tissue breakdown will help to prevent secondary disability and morbidity in the amputee population. ..
  10. Internal Barriers to Seeking Smoking Cessation Treatment
    John Hughes; Fiscal Year: 2007
    ..Our results will suggest messages for media campaigns and for clinicians to use to motivate smokers to access proven treatments. ..
  11. Dentin/Adhesive Interface Structure/Property Imaging
    Yong Wang; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  12. INTERFACE MECHANICS, MATERIALS, AND TISSUE RESPONSE
    Joan Sanders; Fiscal Year: 2002
    ....
  13. CONTROLLED-RELEASE SEALANT TO PREVENT SECONDARY CARIES
    Kenneth Anusavice; Fiscal Year: 2004
    ..mutans, site specific levels of S. mutans at the margins of amalgam and composite restorations, and the width of marginal crevices adjacent to amalgam and composite restorations). ..
  14. INTERFACE MECHANICS, MATERIALS, AND TISSUE RESPONSE
    Joan Sanders; Fiscal Year: 2003
    ....
  15. Brief Dental Office Intervention with Tobacco Quitline
    Jon Ebbert; Fiscal Year: 2005
    ..S. adult population smoking; and 3) 75% of smokers quitting for at least one day or longer because they are trying to quit. ..
  16. PH SENSITIVE COMPLEX HYDROGEL FOR PROTEIN DRUG RELEASE
    NIKOLAOS PEPPAS; Fiscal Year: 2001
    ..Finally, the insulin delivery efficacy of these novel devices will be tested using in vivo experiments. ..
  17. NEW BIOMATERIALS TO MINIMIZE SCAR TISSUE FORMATION
    Joan Sanders; Fiscal Year: 2002
    ..e. soft-tissue complications that require surgical repair through use of a biomaterial. The new materials will prevent scar tissue formation and reduce the occurrence of secondary complications. ..
  18. CERAMIC WHISKER REINFORCEMENT OF DENTAL COMPOSITE RESINS
    HUAKUN XU; Fiscal Year: 2002
    ....
  19. UMKC School of Dentistry Oral and Craniofacial Biology
    J Eick; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  20. Determinants of the Durability of Resin-Dentin Bonds
    David Pashley; Fiscal Year: 2006
    ..This should provide important new insight into designing more durable resin-dentin bonds that can justify the placement of resin-based posterior composites. ..
  21. MAINTENANCE TREATMENT FOR PREVENTION OF SMOKING RELAPSE
    Lirio Covey; Fiscal Year: 2004
    ..abstract_text> ..
  22. High Dose Nicotine Patch Therapy for Spit Tobacco Users
    Jon Ebbert; Fiscal Year: 2004
    ..Our goal is to reduce the prevalence of ST use and decrease the incidence of oropharyngeal cancer through the development of effective treatment options for ST users. ..
  23. Genetic and Tissue Engineering for Aneurysms
    David Kallmes; Fiscal Year: 2004
    ..Successful implementation of this research program will advance the field of genetic and tissue engineering and will improve the care of patients harboring life-threatening cerebral aneurysms. ..
  24. Evaluating Nicotine Lozenges for Treatment of Smokeless Tobacco Addiction
    Jon Ebbert; Fiscal Year: 2009
    ..No drug therapies have been shown to be effective for helping smokeless tobacco users quit for good. The purpose of this study is to test drugs that can be used to help smokeless tobacco users quit for good. ..
  25. Improved Animal Modeling of Saccular Aneurysms
    David F Kallmes; Fiscal Year: 2010
    ..This program will enhance health by preventing the catastrophic events resulting from spontaneous rupture of intracranial aneurysms. ..
  26. SHAM-CONTROLLED TRIAL OF PERCUTANEOUS VERTEBROPLASTY
    David Kallmes; Fiscal Year: 2008
    ..abstract_text> ..
  27. IMPROVED PREVENTIVE/RESTORATIVE RESINS AND COMPOSITES
    SABINE DICKENS; Fiscal Year: 2006
    ..The data gathered in these experiments will serve to support a larger R01 grant application with the long-term objectives of developing improved durable materials for adhesives and adhesive composites. [unreadable] [unreadable]..
  28. RESIN-BASED REMINERALIZING CEMENTS AND COMPOSITES
    SABINE DICKENS; Fiscal Year: 2009
    ..Completion of this research will lead to Ca- PO4 cements and composites with improved adhesion to dentin and improved strength for ART and the treatment of root caries. ..