Genomes and Genes
Summary: Acrylic acids or acrylates which are substituted in the C-2 position with a methyl group.
Publications284 found, 100 shown here
- Prostanoids as pharmacological targets in COPD and asthmaStephanie Rolin
Department of Pharmacy, University of Namur, Rue de Bruxelles 61, B 5000 Namur, Belgium
Eur J Pharmacol 533:89-100. 2006..This article aims to provide an overview of the role of prostanoids and isoprostanes in the pathogenesis of COPD and asthma and to discuss the pharmacological strategies developed in prevention and/or treatment of these pathologies...
- Nanoleakage, ultramorphological characteristics, and microtensile bond strengths of a new low-shrinkage composite to dentin after artificial agingSillas Duarte
Department of Comprehensive Care, Case Western Reserve University, School of Dental Medicine, 10900 Euclid Avenue, Cleveland, OH 44106 4905, USA
Dent Mater 25:589-600. 2009..The null hypotheses tested were (1) aging does not affect the bonding of low-shrinkage composite; (2) there is no difference in microtensile bond strengths and nanoleakage using different bonding strategies...
- Contraction stress of low-shrinkage composite materials assessed with different testing systemsGiulio Marchesi
Department of Biomedicine, Unit of Dental Sciences and Biomaterials, University of Trieste, Trieste, Italy
Dent Mater 26:947-53. 2010..It was hypothesized that the silorane-based material and the low-shrinkage nanohybrid composite would exhibit lower contraction stress than dimethacrylate-based composites irrespective of measuring system...
- Macro-, micro- and nano-mechanical investigations on silorane and methacrylate-based compositesNicoleta Ilie
Department of Restorative Dentistry, Dental School of the Ludwig Maximilians University, Goethestr 70, 80336 Munich, Germany
Dent Mater 25:810-9. 2009....
- Effect of surface pre-treatment on durability of resin-based cements bonded to titaniumYouhei Tsuchimoto
Department of Oral and Maxillofacial Rehabilitation, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan
Dent Mater 22:545-52. 2006..Titanium has in recent years become a material of great opportunities in dentistry and orthopedics. In this study, we searched for a method to effectively pre-treat titanium as part of an adhesive luting and/or resin-veneering procedure...
- Direct and indirect effects of the fungicide azoxystrobin in outdoor brackish water microcosmsKerstin Gustafsson
School of Life Sciences, Södertörn University, Huddinge, Sweden
Ecotoxicology 19:431-44. 2010....
- Perspectives on the use of melatonin to reduce cytotoxic and genotoxic effects of methacrylate-based dental materialsJanusz Blasiak
Department of Molecular Genetics, University of Lodz, Lodz, Poland
J Pineal Res 51:157-62. 2011..This opens a new possible application of melatonin to improve properties of biomaterials used in dentistry...
- Genotoxicity and cytotoxicity of dental materials in human lymphocytes as assessed by the single cell microgel electrophoresis (comet) assayNorbert H Kleinsasser
Klinisch experimentelle Onkologie, Department of Otolaryngology Head and Neck Surgery, Ludwig Maximilians University Munich, Munich, Germany
J Dent 32:229-34. 2004..Whereas the cytotoxic potential of some components has been clearly documented, possible genotoxicity in human target cells demands further investigation...
- Induction of DNA double-strand breaks in primary gingival fibroblasts by exposure to dental resin compositesEbru Urcan
Walther Straub Institute of Pharmacology and Toxicology, Ludwig Maximilians University of Munich, Nussbaumstrasse 26, D 80336 Munich, Germany
Biomaterials 31:2010-4. 2010..25 and 0.5gamma-H2AX foci/HGF cell. Our results for the first time show that exposure to dental resin monomers can induce DSBs in primary human oral cavity cells, which underscores their genotoxic capacity...
- Biocompatibility of resin-modified filling materialsW Geurtsen
Department of Conservative Dentistry and Periodontology, Medical University Hannover, Germany
Crit Rev Oral Biol Med 11:333-55. 2000..Therefore, it is critical, both for our patients and for the profession, that the biological effects of resin-based filling materials be clarified in the near future...
- Effect of C-factor on microtensile bond strengths of low-shrinkage compositesN A El-Sahn
Department of Operative Dentistry, Cairo University, Cairo, Egypt
Oper Dent 36:281-92. 2011..Filtek Z250/Adper Single Bond Plus (Z, 3M ESPE, St Paul, MN, USA) was used as a control...
- Effect of wet vs. dry testing on the mechanical properties of hydrophilic self-etching primer polymersKeiichi Hosaka
Cariology and Operative Dentistry, Department of Restorative Sciences, Tokyo Medical and Dental University, Tokyo, Japan
Eur J Oral Sci 115:239-45. 2007..Both E and UTS correlated significantly with the BisGMA concentration of the polymers, either wet or dry. The percentage changes in E or UTS were significantly correlated with the water sorption of the polymers...
- Identification of glutathione-methacrylates adducts in gingival fibroblasts and erythrocytes by HPLC-MS and capillary electrophoresisGiuseppina Nocca
Institute of Biochemistry and Clinical Biochemistry, Catholic University, Rome, Italy
Dent Mater 27:e87-98. 2011..GSH can detoxify methacrylates by conjugating their α,β-unsaturated carbon-carbon moiety to the thiol group, with the catalysis of ..
- Dental methacrylates may exert genotoxic effects via the oxidative induction of DNA double strand breaks and the inhibition of their repairJanusz Blasiak
Department of Molecular Genetics, University of Lodz, Pomorska 141 143, 90 236 Lodz, Poland
Mol Biol Rep 39:7487-96. 2012..while sodium ascorbate or melatonin improved the efficacy of H(2)O(2)-induced damage in the presence of the methacrylates. The adhesive induced a rise in the G2/M cell population, accompanied by a reduction in the S cell population ..
- The influence of short and medium-term water immersion on the hydrolytic stability of novel low-shrink dental compositesW M Palin
Biomaterials Unit, School of Dentistry, University of Birmingham, St Chad s Queensway, Birmingham B4 6NN, UK
Dent Mater 21:852-63. 2005....
- Influence of polymer architecture and molecular weight of poly(2-(dimethylamino)ethyl methacrylate) polycations on transfection efficiency and cell viability in gene deliveryChristopher V Synatschke
Makromolekulare Chemie II und Bayreuther Zentrum für Kolloide und Grenzflächen, Universitat Bayreuth, Bayreuth, Germany
Biomacromolecules 12:4247-55. 2011....
- N-acetyl cysteine directed detoxification of 2-hydroxyethyl methacrylate by adduct formationGiuseppina Nocca
Institute of Biochemistry and Clinical Biochemistry, Catholic University, Rome, Italy
Biomaterials 31:2508-16. 2010..Moreover, we provide evidence that the actual intracellular concentration of HEMA able to cause cytotoxic effects is at least one magnitude lower than that applied extracellularly...
- Enzymatic biodegradation of HEMA/bisGMA adhesives formulated with different water contentElisabet L Kostoryz
Pharmacology and Toxicology Division, School of Pharmacy, University of Missouri Kansas City, Kansas City, Missouri, USA
J Biomed Mater Res B Appl Biomater 88:394-401. 2009....
- Influence of resin monomers on growth of oral streptococciY Takahashi
Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, 1 8 Yamadaoka, Suita, Osaka 565 0871, Japan
J Dent Res 83:302-6. 2004....
- Cytotoxicity and genotoxicity of glycidyl methacrylateTomasz Poplawski
Department of Molecular Genetics, University of Lodz, Lodz, Poland
Chem Biol Interact 180:69-78. 2009b>Methacrylates are used in the polymer form as composite restorative materials in dentistry...
- A selective thromboxane A2 (TXA2) synthase inhibitor, ozagrel, attenuates lung injury and decreases monocyte chemoattractant protein-1 and interleukin-8 mRNA expression in oleic acid-induced lung injury in guinea pigsYoichi Ishitsuka
Department of Clinical Chemistry and Informatics, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Japan
J Pharmacol Sci 111:211-5. 2009..Administration of ozagrel prevented these changes associated with OA injection. Ozagrel is a promising drug candidate for preventing acute lung injury...
- Cytotoxicity of the dental composite component TEGDMA and selected metabolic by-products in human pulmonary cellsJudith Emmler
Bundeswehr Institute of Pharmacology and Toxicology, 80937 Munich, Germany
Dent Mater 24:1670-5. 2008..Metabolic by-products formerly associated with TEGDMA-degradation include triethylene glycol (TEG), methacrylic acid (MA), 2,3-epoxymethacrylic acid (2,3-EMA), and formaldehyde...
- Effect of 2-hydroxyethyl methacrylate on human pulp cell survival pathways ERK and AKTGianrico Spagnuolo
Department of Oral and Maxillofacial Sciences and Interdisciplinary Research Centre on Biomaterials CRIB, University of Naples Federico II, Naples, Italy
J Endod 34:684-8. 2008..Our findings demonstrated that HEMA exposure modulates the ERK and AKT pathways in different manners, and that in turn, they function in parallel to mediate pro-survival signaling in pulp cells subjected to HEMA cytotoxicity...
- Quantum-chemical descriptors for estimating hemolytic activity of aliphatic and aromatic methacrylatesMariko Ishihara
Division of Chemistry, Meikai University School of Dentistry, 1 1 Keyakidai, Sakado, Saitama 350 0283, Japan
Chemosphere 70:1898-902. 2008b>Methacrylates such as methyl methacrylate (6), triethyleneglycol dimethacrylate (5) and bisphenol A glycidyldimethacrylate, bis-GMA, (8) are widely used as materials in dental resins perturbation of the phosphatidylcholine-cholesterol ..
- Push-out strength of translucent fibre posts cemented using a dual-curing technique or a light-curing self-adhering materialL Giachetti
Dental Materials and Restorative Dentistry, Tuscany School of Dental Medicine, University of Florence and Siena, Department of Public Health, Dentistry, University of Florence, Italy
Int Endod J 45:249-56. 2012..To compare by means of a push-out test the interfacial strength of a dual-curing resin cement and a light-curing self-adhering resin composite when used in translucent fibre post cementation...
- Cytotoxic and genotoxic effects of resin monomers in human salivary gland tissue and lymphocytes as assessed by the single cell microgel electrophoresis (Comet) assayNorbert H Kleinsasser
Ecogenotoxicology, Department of Otolaryngology Head and Neck Surgery, University of Regensburg, Franz Josef Strauss Allee 11, D 93042 Regensburg, Germany
Biomaterials 27:1762-70. 2006..In the present study, genotoxic and cytotoxic effects of three common methacrylates are investigated in human samples of salivary glands and peripheral lymphocytes...
- Metabolism of TEGDMA and HEMA in human cellsJürgen Durner
Institute of Clinical Chemistry, Ludwig Maximilians University of Munich, Germany
Biomaterials 31:818-23. 2010..Therefore the epoxide pathway with formation of the epoxy-intermediate 2,3-epoxymethacrylic acid is the main route of metabolisation of HEMA and TEGDMA...
- Conditioning effect on dentin, resin tags and hybrid layer of different acidity self-etch adhesives applied to thick and thin smear layerSilvia Kenshima
University of Sao Paulo, FOUSP, Dental Materials Department, Av Professor Lineu Prestes, 2227, Cidade Universitaria, CEP 05508 000, Sao Paulo, SP, Brazil
J Dent 34:775-83. 2006..to assess the conditioning effect (CE) of self-etch adhesives of different acidity applied to thick and thin smear layer (SL), the corresponding resin tags (RT) and hybrid layer (HL)...
- Microtensile bond strength and interfacial characterization of 11 contemporary adhesives bonded to bur-cut dentinMouhamed Sarr
Universite Cheikh Anta Diop, Faculte de Medecine, Pharmacie et Odontologie, Dakar, Senegal
Oper Dent 35:94-104. 2010..This study evaluated mechanically and ultra-morphologically 11 different adhesive systems bonded to dentin...
- Infrared spectroscopy: a tool for determination of the degree of conversion in dental compositesLuciene Gonçalves Palmeira Moraes
Department of Physics and Chemistry, Sao Paulo State University, Ilha Solteira, SP, Brazil
J Appl Oral Sci 16:145-9. 2008..This paper presents important details to use infrared spectroscopy for determination of the conversion degree...
- Disruption of the alternative oxidase gene in Magnaporthe grisea and its impact on host infectionCruz Avila-Adame
Department of Plant Pathology, Cornell University, New York State Agricultural Experiment Station, Geneva 14456, USA
Mol Plant Microbe Interact 15:493-500. 2002..Rather, alternative respiration provided protection from azoxystrobin during both saprophytic and infectious stages of the pathogen. The nature of similar oxidative stress conditions in the ecology of M. grisea remains an open question...
- Influence of fatigue loading on four post-and-core systems in maxillary premolarsPeter Bolhuis
Department of Dental Materials Science, ACTA, Amsterdam, The Netherlands
Quintessence Int 35:657-67. 2004..As the stiffness of posts may affect the outcome, post-and-core systems with varying post stiffness were selected...
- Physical properties of a new silorane-based restorative systemWen Lien
Advanced Education in General Dentistry Residency, Wilford Hall Medical Center, Lackland AFB, TX 78236, USA
Dent Mater 26:337-44. 2010..To distinguish the physical properties of a new silorane-based restorative material in comparison to five methacrylate-based restorative materials--a compomer, giomer, nanocomposite, hybrid and micro-hybrid...
- Siloranes in dental compositesWolfgang Weinmann
3M ESPE, Seefeld, Germany
Dent Mater 21:68-74. 2005..The purpose of this study was to compare the product profile of a Silorane based composite which polymerizes by a cationic ring opening process with the product profile of different methacrylate based restoratives...
- Eluted substances from unpolymerized and polymerized dental restorative materials and their Nernst partition coefficientJürgen Durner
Institute of Clinical Chemistry, Faculty of Medicine, Campus Grosshadern, Ludwig Maximilians University of Munich, Marchioninistrasse 15, 81377 Munich, Germany
Dent Mater 26:91-9. 2010..The study was performed to investigate the elution of substances from unpolymerized and polymerized composites (Tetric=TET; Arabesk=ARA), ormoceres (Admira)=ADM; Definite=DEF) and the compomere (Hytac=HYT)...
- Antibacterial activity and bonding characteristics of an adhesive resin containing antibacterial monomer MDPBSatoshi Imazato
Department of Restorative Dentistry and Endodontology, Graduate School of Dentistry, Osaka University, 1 8 Yamadaoka, Suita, Osaka 565 0871, Japan
Dent Mater 19:313-9. 2003....
- Effects of HEMA on type I collagen protein in human gingival fibroblastsM Falconi
Dipartimento di Scienze Anatomiche Umane e Fisiopatologia dell Apparato Locomotore, Universita di Bologna, Italy
Cell Biol Toxicol 23:313-22. 2007..From these results, we conclude that low concentrations of HEMA can significantly alter the morphology of human gingival fibroblasts and interfere with the presence of type I collagen protein...
- Induction of DNA strand breaks by dental composite components compared to X-ray exposure in human gingival fibroblastsJürgen Durner
Department of Operative Restorative Dentistry, Periodontology and Pedodontics, Ludwig Maximilians University of Munich, Goethestrasse 70, 80336 Munich, Germany
Arch Toxicol 85:143-8. 2011..But 0.25 mM BisGMA is more than 100-fold higher than that concentration found in worst case calculations. Therefore, our data did not support our hypothesis...
- Immediate repair bond strengths of microhybrid, nanohybrid and nanofilled composites after different surface treatmentsMargareta Rinastiti
Department of Biomedical Engineering, University Medical Center Groningen, University of Groningen, 9713 AV Groningen, The Netherlands
J Dent 38:29-38. 2010..To evaluate immediate repair bond strengths and failure types of resin composites with and without surface conditioning and characterize the interacting composite surfaces by their surface composition and roughness...
- Combination of integrin-binding peptide and growth factor promotes cell adhesion on electron-beam-fabricated patternsChristopher M Kolodziej
Department of Chemistry and Biochemistry and the California NanoSystems Institute, University of California, Los Angeles, 607 Charles E Young Drive South, Los Angeles, California 90095, USA
J Am Chem Soc 134:247-55. 2012..The results also suggest positive implications for addition of growth factors into adhesive patterns for cell-material interactions...
- Influence of oxygen inhibition on the surface free energy and enamel bond strength of self-etch adhesivesKoji Oyama
Department of Operative Dentistry, Nihon University School of Dentistry, 1 8 13, Kanda Surugadai, Chiyoda ku, Tokyo 101 8310, Japan
Dent Mater J 31:26-31. 2012..The enamel bond strengths of the self-etch adhesives were significantly lower in the specimens without an oxygen-inhibited layer. The oxygen-inhibited layer therefore appeared to promote higher enamel bond strength...
- Nanoscale growth factor patterns by immobilization on a heparin-mimicking polymerKaren L Christman
Department of Chemistry and Biochemistry, University of California, Los Angeles, 607 Charles E Young Drive East, Los Angeles, California 90095 1569, USA
J Am Chem Soc 130:16585-91. 2008..Fluorescence microscopy confirmed that bFGF and VEGF were subsequently immobilized to the polymer micro- and nanopatterns...
- Effect of composition, viscosity and thickness of the opaquer on the adhesion of resin composite to titaniumMutlu Ozcan
University of Zurich, Dental Materials Unit, Center for Dental and Oral Medicine, Clinic for Fixed and Removable Prosthodontics and Dental Materials Science, Plattenstrasse 11, CH 8032, Zurich, Switzerland
Dent Mater 25:1248-55. 2009....
- Redox-cleavable star cationic PDMAEMA by arm-first approach of ATRP as a nonviral vector for gene deliveryFengying Dai
School of Materials Science and Engineering, Tianjin Key Laboratory of Composite and Functional Materials, Tianjin University, Tianjin, PR China
Biomaterials 31:559-69. 2010..The effect of medium pH on the star PDMAEMA system was smaller owing to the ability of densely tertiary amino groups along multiple arms to absorb more protons, which was favorable for endosomolytic escape of complexes...
- Dual-responsive magnetic core-shell nanoparticles for nonviral gene delivery and cell separationAlexander P Majewski
Makromolekulare Chemie II, Universitat Bayreuth, 95440 Bayreuth, Germany
Biomacromolecules 13:857-66. 2012..Moreover, after transfection with the hybrid nanoparticles, the cells acquired magnetic properties that could be used for selective isolation of transfected cells...
- Ternary complexes of amphiphilic polycaprolactone-graft-poly (N,N-dimethylaminoethyl methacrylate), DNA and polyglutamic acid-graft-poly(ethylene glycol) for gene deliveryShutao Guo
Department of Polymer Science and Technology, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
Biomaterials 32:4283-92. 2011....
- Effects of the incorporation of a hydrophobic middle block into a PEG-polycation diblock copolymer on the physicochemical and cell interaction properties of the polymer-DNA complexesRahul Sharma
School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907, USA
Biomacromolecules 9:3294-307. 2008..Between the micelleplexes and the PEG-PDMAEMA polyplexes, a higher gene transfection efficiency is observed with the latter system. All three formulations show comparable levels of cytotoxicity in HeLa cells...
- Evaluating resin-enamel bonds by microshear and microtensile bond strength tests: effects of composite resinAndrea Mello de Andrade
Dental School, Department of Dental Materials, University of Sao Paulo, Sao Paulo, SP, Brazil
J Appl Oral Sci 18:591-8. 2010....
- Comparison of silorane and methacrylate-based composite resins on the curing light transmissionRicardo Danil Guiraldo
Department of Restorative Dentistry, School of Dentistry, University of North Parana, Londrina, PR, Brazil
Braz Dent J 21:538-42. 2010..The DKH of Filtek P90 (25%) was significantly higher than that of Heliomolar (12%). There was a greater degree of subsurface polymerization of the methacrylate-based composite compared to the silorane-based composite...
- Bond strength of adhesive systems to human tooth enamelThais Cachute Paradella
Department of Bioscience and Oral Diagnosis, Sao Paulo State University, Sao Paulo, SP, Brazil, CEP 12243 080
Braz Oral Res 21:4-9. 2007..In conclusion, although the total etching and self-etching systems presented similar shear bond strength values, the types of fracture presented by them were different, which can have clinical implications...
- Effect of 2-hydroxyethyl methacrylate on Streptococcus spp. biofilmsS D'Ercole
Department of Biomedical Sciences, University G D Annunzio, Chieti Pescara, Chieti, Italy
Lett Appl Microbiol 52:193-200. 2011..The effect of different concentrations of 2-hydroxyethyl methacrylate (HEMA) was evaluated on biofilm formation and preformed biofilm of Streptococcus mitis, Streptococcus mutans and Streptococcus oralis, alone or combined to each other...
- Bond strength of two resin cements to titanium after different surface conditioning methodsMutlu Ozcan
University of Zurich, Head of Dental Materials Unit, Center for Dental and Oral Medicine Clinic for Fixed and Removable Prosthodontics and Dental Materials Science, Switzerland
Gen Dent 60:e6-e12. 2012....
- The repair potential of resin composite materialsChaiwat Maneenut
Faculty of Dentistry, Chulalongkorn University, Henri Dunant Rd, Bangkok, Thailand
Dent Mater 27:e20-7. 2011....
- Effect of incorporation of 2-tert-butylaminoethyl methacrylate on flexural strength of a denture base acrylic resinAndré Gustavo Paleari
Department of Dental Materials and Prosthodontics, Araraquara Dental School, Sao Paulo State University, Araraquara, SP, Brazil
J Appl Oral Sci 19:195-9. 2011..It is hypothesized that the 2-tert-butylaminoethyl methacrylate (TBAEMA) incorporated to acrylic resins should have antimicrobial activity related to the presence of amino groups on acrylic resin surface...
- Effect of metal primers on bond strength of resin cements to base metalsRenata Garcia Fonseca
Department of Dental Materials and Prosthodontics, Araraquara Dental School, Sao Paulo State University UNESP, Araraquara, Sao Paulo, Brazil
J Prosthet Dent 101:262-8. 2009..A strong and durable bond between a metal framework and a resin-based luting agent is desired. Metal primers have been shown to be very effective on noble alloys. However, there is insufficient information about their effect on base metals...
- Adhesive bonding of resin cements to cast titanium with adhesive primersMarina Di Francescantonio
Department of Restorative Dentistry, Piracicaba Dental School, University of Campinas, SP, Brazil
Braz Dent J 23:218-22. 2012..Panavia F 2.0 and RelyX ARC yielded high bond strength means with or without adhesive primers. The use of adhesive primers might increase the bond strength to cast titanium depending on the resin cement used...
- Six-month evaluation of a resin/dentin interface created by methacrylate and silorane-based materialsRenata Kirita Doi Sampaio
University North of Parana, Londrina, PR, Brazil
J Appl Oral Sci 21:80-4. 2013..This study aimed to compare the micro-tensile bond strength of methacrylate resin systems to a silorane-based restorative system on dentin after 24 hours and six months water storage...
- Does the acidity of self-etching primers affect bond strength and surface morphology of enamel?Sandra Kiss Moura
Department of Dental Materials, University of Sao Paulo, FOUSP, Brazil
J Adhes Dent 8:75-83. 2006..This study examined the ultrastructure and microtensile bond strengths (TBS) of self-etching (with different acidity) and conventional adhesive systems bonded to unground enamel...
- Effect of silane coupling agents and alloy primers on adhesion to titaniumM Ozcan
Unit of Dental Materials, University of Zurich, Zurich, Switzerland
Minerva Stomatol 60:427-34. 2011..This study evaluated the adhesion of resin composite to titanium alloy using different silane coupling agents and alloy primers in combination with surface conditioning methods after aging...
- Phosphorylcholine-polycation diblock copolymers as synthetic vectors for gene deliveryJ K W Lam
School of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, UK
J Control Release 100:293-312. 2004....
- Alterations of energy metabolism and glutathione levels of HL-60 cells induced by methacrylates present in composite resinsG Nocca
Biochemistry and Clinical Biochemistry Institute, School of Medicine, Catholic University, Rome, Italy
J Dent 35:187-94. 2007....
- TEM characterization of a silorane composite bonded to enamel/dentinAtsushi Mine
Leuven BIOMAT Research Cluster, Department of Conservative Dentistry, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Catholic University of Leuven, Kapucijnenvoer 7, Leuven, Belgium
Dent Mater 26:524-32. 2010..The purpose of this study was to characterize the interfacial ultra-structure at enamel and dentin using transmission electron microscopy (TEM)...
- Effects of triazine dithione and hydrophobic phosphate monomers on bonding to Ag-Pd-Cu-Au alloy and titanium with a methacrylic resin-based luting agentHiroyasu Koizumi
Department of Fixed Prosthodontics, and Division of Advanced Dental Treatment, Dental Research Center, Nihon University School of Dentistry, Chiyoda ku, Tokyo, Japan
J Adhes Dent 12:215-22. 2010..The purpose of the current study was to evaluate the effects of thione and phosphate functional monomers on bond strength and durability of a methacrylic resin luting agent joined to silver-palladium based alloy and titanium...
- Evaluation of a new universal primer for ceramics and alloysFarhad Azimian
Department of Prosthodontics, Propaedeutics and Dental Materials, School of Dentistry, Christian Albrechts University, Kiel, Germany
J Adhes Dent 14:275-82. 2012..To evaluate in vitro the effect of using a universal primer on the resin bond strength to ceramics (silicate and zirconia) and two noble alloys for metal-ceramic restorations...
- The effect of phosphoric acid pre-etching and thermocycling on self-etching adhesive enamel bondingJames L Sheets
Department of Prosthodontics, Creighton University School of Dentistry, Omaha, NE 68178, USA
J Prosthet Dent 107:102-8. 2012....
- The inhibitory effects of quaternary ammonium methacrylates on soluble and matrix-bound MMPsA Tezvergil-Mutluay
Department of Prosthodontics and Turku Clinical Biomaterials Center, University of Turku, Institute of Dentistry, Lemminkaisenkatu 2, FI 20520 Turku, Finland
J Dent Res 90:535-40. 2011..This study evaluated the MMP-inhibiting potential of quaternary ammonium methacrylates (QAMs), with soluble rhMMP-9 and a matrix-bound endogenous MMP model...
- Adhesive bonding of Ti-6Al-7Nb alloy and component metals with acidic primers and a tri-n-butylborane initiated resinHiroyasu Koizumi
Department of Fixed Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan
J Adhes Dent 14:283-92. 2012..To evaluate the effects of acidic functional monomers on the bond strength and durability of an acrylic resin joined to Ti-6Al-7Nb alloy and component metals...
- Hybrid cell death induced by exposure to 2-hydroxyethyl methacrylate (HEMA): an ultrastructural and X-ray microanalytical studyIsmael A Rodriguez
Histology Department B, Faculty of Odontology, National University of Cordoba, Cordoba, Argentina
J Adhes Dent 10:105-11. 2008....
- Antioxidative vitamins decrease cytotoxicity of HEMA and TEGDMA in cultured cell linesU I Walther
Walther Straub Institut für Pharmakologie und Toxikologie der Ludwig Maximilians Universität, Nussbaumstr 26, 80336 Munchen, Germany
Arch Oral Biol 49:125-31. 2004....
- Effects of mechanical cycling on the bonding of zirconia and fiber posts to human root dentinMarco Antonio Bottino
Department of Dental Materials and Prosthodontics, Sao Jose dos Campos Dental School, Sao Paulo State University UNESP, Brazil
J Adhes Dent 9:327-31. 2007..To evaluate the effect of cyclical mechanical loading on the bond strength of a fiber and a zirconia post bonded to root dentin...
- The stability of methacrylate biomaterials when enzyme challenged: kinetic and systematic evaluationsD M Yourtee
Division of Pharmacology, Toxicore Laboratory, School of Pharmacy, University of Missouri, Kansas City, Missouri 64108, USA
J Biomed Mater Res 57:522-31. 2001..Particularly resistant were aromativ derivatives and those with branching in methacrylate linkages. Overall, the study confirms the ability of physiologically important esterases to catalyze the hydrolysis of biomaterial methacrylates.
- Effects of aging and HEMA content on the translucency, fluorescence, and opalescence properties of experimental HEMA-added glass ionomersYong keun Lee
Denforus Co, I B Diosuperium, Seocho Gu, Seoul, Korea
Dent Mater J 29:9-14. 2010..In addition, results of this study showed that apart from optimal HEMA ratio, future studies should include other aspects and factors that contribute to age-dependent changes in optical properties...
- Identification of 2,3-epoxymethacrylic acid as an intermediate in the metabolism of dental materials in human liver microsomesMario Seiss
Walther Straub Institute of Pharmacology and Toxicology, Ludwig Maximilians University of Munich, 80336 Munich, Germany
Dent Mater 23:9-16. 2007..This study was performed to identify the possible dental material intermediate 2,3-epoxymethacrylic acid (2,3-EMA) from MA in human liver microsomes. Most epoxy compounds are regarded as highly toxic substances...
- The effect of ferrule on the fracture mode of endodontically treated canines restored with fibre posts and metal-ceramic or all-ceramic crownsTheodora Fragou
Department of Fixed Prosthesis and Implant Prosthodontics, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece
J Dent 40:276-85. 2012....
- HEMA reduces cell proliferation and induces apoptosis in vitroJ T Samuelsen
NIOM Nordic Institute of Dental Materials, N 1305 Haslum, Norway
Dent Mater 24:134-40. 2008..The aim of this study was to investigate potential cellular responses following long-term exposure to relatively low and potentially more clinical relevant HEMA concentrations...
- Thermally responsive injectable hydrogel incorporating methacrylate-polylactide for hydrolytic labilityZuwei Ma
McGowan Institute for Regenerative Medicine, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15219, USA
Biomacromolecules 11:1873-81. 2010..The synthesized hydrogels provide new options for biomaterial injection therapy where increased mechanical strength and relatively slow resorption rates would be attractive...
- Inhibition of TXA synthesis with OKY-046 improves liver preservation by prolonged hypothermic machine perfusion in ratsHongzhi Xu
Department of Biology, University of North Carolia at Charlotte, Charlotte, North Carolina 28223, USA
J Gastroenterol Hepatol 23:e212-20. 2008..The underlying injury mechanism is not well understood. The present study sought to investigate the role of thromboxane A(2) (TXA(2)) in the pathogenesis of liver injury after prolonged HMP...
- Respiratory effects of exposure to methacrylates among dental assistantsM S Jaakkola
Institute of Occupational and Environmental Medicine, University of Birmingham, Birmingham, UK
Allergy 62:648-54. 2007..published, but there is little data on the risk of respiratory disorders related to occupational exposure to methacrylates in dental assistants...
- Development of microporous drug-releasing films cast from artificial nanosized latexes of poly(styrene-co-methyl methacrylate) or poly(styrene-co-ethyl methacrylate)Daniel P Otto
School of Pharmacy, University of Wisconsin Madison, WI 53705, USA
Eur J Pharm Biopharm 69:1121-34. 2008..Depending on the application, one could select the copolymer films that best suited the application i.e. for short-term drug release applications such as urinary catheters or long-term applications such as artificial implants...
- Infrared reflection absorption spectroscopy coupled with Brewster angle microscopy for studying interactions of amphiphilic triblock copolymers with phospholipid monolayersElkin Amado
Department of Chemistry, Martin Luther University Halle Wittenberg, Halle Saale, Germany
Langmuir 24:10041-53. 2008....
- Characterisation of QoI-resistant field isolates of Botrytis cinerea from citrus and strawberryHideo Ishii
National Institute for Agro Environmental Sciences, Tsukuba, Ibaraki 305 8604, Japan
Pest Manag Sci 65:916-22. 2009..Biological and molecular characterisation of resistant isolates was conducted in this study...
- In vitro stability of methylmethacrylic acid, TEGDMA and HEMA exposed to esterasesMario Seiss
Walther Straub Institute of Pharmacology and Toxicology, Ludwig Maximilians University of Munich, 80336 Munich, Germany
Dent Mater 25:1044-9. 2009....
- Volatile methacrylates in dental practicesWolfgang Marquardt
Department of Operative Dentistry and Periodontology, Ludwig Maximilians University, Munich, Germany
J Adhes Dent 11:101-7. 2009In recent years, an increase of occupational respiratory diseases, such as asthma caused by methacrylates, has been observed in dental personnel...
- Dynamic mechanical analysis and esterase degradation of dentin adhesives containing a branched methacrylateJong Gu Park
Bioengineering Research Center, University of Kansas, Lawrence, Kansas, USA
J Biomed Mater Res B Appl Biomater 91:61-70. 2009..The improved esterase resistance of the new adhesive could be explained in terms of the densely crosslinked network structure and/or the steric hindrance of branched alkyl side chains...
- Designing temperature-responsive biocompatible copolymers and hydrogels based on 2-hydroxyethyl(meth)acrylatesOlga V Khutoryanskaya
Reading School of Pharmacy, University of Reading, Whiteknights, P O Box 224, RG6 6AD, Reading, United Kingdom
Biomacromolecules 9:3353-61. 2008..The assessment of the biocompatibility of the copolymers using the slug mucosal irritation test revealed that they are also less irritant than poly(acrylic acid)...
- Influence of incorporation of fluoroalkyl methacrylates on roughness and flexural strength of a denture base acrylic resinTatiana Ramirez Cunha
Dental School of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, Brazil
J Appl Oral Sci 17:103-7. 2009..The addition of FMA into denture base resin may lower the flexural strength and modulus of elasticity, regardless of the tested concentration...
- Mechanisms of N-acetyl cysteine-mediated protection from 2-hydroxyethyl methacrylate-induced apoptosisAvina Paranjpe
The Jane and Jerry Weintraub Center for Reconstructive Biotechnology, The Jonsson Comprehensive Cancer Center JCCC, Dental Research Institute, Division of Oral Biology and Medicine, Los Angeles, CA, USA
J Endod 34:1191-7. 2008..Overall, the results reported in this article indicate that NAC is an effective chemoprotectant that can safely be used to protect the pulp and the surrounding tissues from adverse effects of dental restorative and endodontic materials...
- Novel hydrogel membrane based on copoly(hydroxyethyl methacrylate/p-vinylbenzyl-poly(ethylene oxide)) for biomedical applications: properties and drug release characteristicsM Yakup Arica
Biochemical Processing and Biomaterial Research Laboratory, Faculty of Science, Kirikkale University, 71450 Yahşihan Kirikkale, Turkey
Macromol Biosci 5:983-92. 2005..4. This membrane composition provided the best results and can be considered as a potential candidate for a transdermal antibiotic carrier and various biomedical and biotechnological applications...
- Genotoxicity and cytotoxicity of 2-hydroxyethyl methacrylateElzbieta Pawlowska
Department of Pediatric Dentistry, Medical University of Lodz, Pomorska 251, 92 216 Lodz, Poland
Mutat Res 696:122-9. 2010..Chitosan and its derivatives can be considered as additional components of dental restoration to decrease the harmful potency of HEMA...
- Clonal variation in physiological responses of Daphnia magna to the strobilurin fungicide azoxystrobinTrine Perlt Warming
Freshwater Biological Laboratory, University of Copenhagen, Helsingørsgade 51, DK 3400 Hillerød, Denmark
Environ Toxicol Chem 28:374-80. 2009..Thus, ponds in the agricultural areas may experience changes in food-web structure even at very low concentrations of azoxystrobin...
- QSAR models to predict mutagenicity of acrylates, methacrylates and alpha,beta-unsaturated carbonyl compoundsAlfonso Pérez-Garrido
Enviromental Engineering and Toxicology Dpt, Catholic University of San Antonio, Guadalupe, Murcia, Spain
Dent Mater 26:397-415. 2010....
- Occupational skin diseases among dental nursesKristiina Alanko
Finnish Institute of Occupational Health, Helsinki, Finland
Contact Dermatitis 50:77-82. 2004..Plastic gloves or NRL gloves with a low-protein content are recommended for dental work. Skin exposure to (meth)acrylates should be avoided...
- Exposure to airborne methacrylates and natural rubber latex allergens in dental clinicsM L Henriks-Eckerman
Turku Regional Institute of Occupational Health, Turku, Finland
J Environ Monit 3:302-5. 2001The exposure of dental personnel to airborne methacrylates and natural rubber latex (NRL) allergens was studied during placing of composite resin restorations in six dental clinics in Finland...
- Methacrylates in dental restorative materialsMaj Len Henriks-Eckerman
Turku Regional Institute of Occupational Health, Hameenkatu 10, FIN 20500 Turku, Finland
Contact Dermatitis 50:233-7. 2004..Acetone-soluble methacrylates of 7 bonding materials, 8 composite resins and 2 glass ionomers were identified by gas chromatography with ..
- Residues of azoxystrobin from grapes to raisinsChaido Lentza-Rizos
National Agricultural Research Foundation, 1 Sophocli Venizelou Street, 141 23 Lykovrissi, Greece
J Agric Food Chem 54:138-41. 2006..51-1.49 (treatment 1) and 1.42-2.08 mg/kg (treatment 2), with residue transfer factors sometimes >1, even following alkali treatment, which reduced residues considerably. To avoid trade problems, a higher MRL for raisins is necessary...
- Occupational asthma caused by sculptured nails containing methacrylatesRiitta Sauni
Team of Occupational Medicine, Finnish Institute of Occupational Health, Helsinki, Finland
Am J Ind Med 51:968-74. 2008In recent decades, the use of artificial nails including methacrylates (MAs) has increased. This study presents the first two clinical cases of occupational asthma (OA) caused by sculptured nails containing MAs.
- The microleakage between alloy and polymeric materials in veneer crownsSorin Lakatos
Department of Dental Materials and Prosthesis Technology, University School of Dentistry Timişoara, Romania
Quintessence Int 34:295-300. 2003..This study investigated the cervical microleakage between a cobalt-chromium (Co-Cr) alloy and four indirect polymeric veneering materials using different adhesive systems...
- Bonding of prosthetic composite material to Ti-6Al-7Nb alloy with eight metal conditioners and a surface modification techniqueH Yanagida
Department of Fixed Prosthodontics, Nagasaki University School of Dentistry, Japan
Am J Dent 14:291-4. 2001....
- Influence of hyperbranched multi-methacrylates for dental neat resins on proliferation of human gingival fibroblastsQ Wan
College of Dentistry, The Ohio State University, 305 West 12th Street, P.O. Box 182357, Columbus, Ohio 43218-2357, USA
Biomacromolecules 2:217-22. 2001..All these results suggest that the biocompatibility of H-MMA-modified dental neat resins is as good as that of commercially used BisGMA/TEGDMA resin and H-MMA has potential applications in dental composites...
- Effects of cavity configuration on composite restorationKyoung Kyu Choi
Department of Conservative Dentistry, School of Dentistry, Kyunghee University, Seoul, Korea
Oper Dent 29:462-9. 2004..Mean microtensile bond strength to dentin was also decreased with increasing C-factor for both types of composites. Microleakage scores for the hybrid composite restorations were generally higher than the microhybrid composite...
- Alternative oxidase reduces the sensitivity of Mycosphaerella graminicola to QOI fungicidesMonica Miguez
Department of Environmental Sciences, University Pablo de Olavide, Seville, Spain
Pest Manag Sci 60:3-7. 2004..Using QOIs preventatively reduces the risk of resistance since the alternative oxidase cannot by itself generate all the energy needed for germination and early infection...
- Biocompatible PEG-Functionalized MethacrylatesWilliam Collins; Fiscal Year: 2003..Macrophage chemotaxis and phagocytosis will be assessed. The morphology of adherent macrophages and HCE- I cells will also be examined with scanning electron microscopy. ..
- Dental Composite Materials Based on Photoinitiated Thiol-Vinyl Sulfone ReactionsChristopher N Bowman; Fiscal Year: 2013..dental restorative materials is plagued by critical problems;they do not achieve complete conversion of the methacrylates and thus leave a great deal of material that can be extracted into the oral environment...
- ORAL MUCOSAL CELL RESPONSES TO DENTAL RESIN COMPONENTSGeorge Schuster; Fiscal Year: 1999..The specific aims of the current proposal are to examine 1) hydrolysis of the methacrylates and their effects on cell lipid metabolism of oral epithelial and connective tissue cells, as well as a non-..
- NOVEL SOLID PHASE SUPPORTS FOR COMBINATORIAL CHEMISTRYJEAN FRECHET; Fiscal Year: 2001..In addition to the direct use of non-traditional monomers, such as methacrylates and substituted styrenes, spatially targeted modification reactions will result in supports allowing unique ..
- NOVEL CROSSLINK POLYMERS FOR DENTAL RESTORATIONSChristopher Bowman; Fiscal Year: 1999..presently used monomer resins by incorporating different dimethacrylates as well as tri-, tetra-, and penta-methacrylates into the reaction mixture...
- Novel Nanostructured Dental Glass-Ionomers for Advanced Dental RestorativesDong Xie; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Novel Amino Acid-Based Glass-Ionomer BiomaterialsDong Xie; Fiscal Year: 2005..abstract_text> ..
- Molecular/Mechanical Imaging of Dentin Bonding SubstrateYong Wang; Fiscal Year: 2007..Results from this work will provide critical, new insight into failure mechanisms at the dentin/adhesive interface; failure that can ultimately lead to premature breakdown of the composite restoration. ..
- IMPROVED PREVENTIVE/RESTORATIVE RESINS AND COMPOSITESSABINE DICKENS; Fiscal Year: 2006..The data gathered in these experiments will serve to support a larger R01 grant application with the long-term objectives of developing improved durable materials for adhesives and adhesive composites. [unreadable] [unreadable]..
- Dentin/Adhesive Interface Structure/Property ImagingYong Wang; Fiscal Year: 2006..unreadable] [unreadable]..
- RESIN-BASED REMINERALIZING CEMENTS AND COMPOSITESSABINE DICKENS; Fiscal Year: 2009..Completion of this research will lead to Ca- PO4 cements and composites with improved adhesion to dentin and improved strength for ART and the treatment of root caries. ..
- Cell Membrane Simulators in Biocompatibility TestingDAVID YOURTEE; Fiscal Year: 2006..This will enable the prediction of destructive properties of untested compounds and ensure the design of new non-toxic membrane dental materials. ..
- AMPHIPATHIC ORAL CHELATORS AND RADIONUCLIDE CONTAMINATIONScott Miller; Fiscal Year: 2008..Because the pharmacology and toxicology of PACA chelators, such as DTPA and EDTA, are quite well understood, the development pathway of the related TT- based chelators may proceed rapidly. ..
- MECHANISMS OF SKELETAL RECONSTITUTION AFTER LACTATIONScott Miller; Fiscal Year: 2004..abstract_text> ..
- The Role of BCL-2 in Corneal Epithelial Cell SheddingDANIELLE ROBERTSON; Fiscal Year: 2008..4) That events leading to increased apoptosis such as UV light signal surface cell apoptosis through the phosphorylation of BCL-2. ..
- Macromolecular Therapy for Improved Treatment of Rheumatoid ArthritisDong Wang; Fiscal Year: 2009..Eventually, this novel delivery system would lead to improved efficacy and safety profiles for treatment of rheumatoid arthritis and other inflammatory joint disorders. ..
- Viral vector-based RNAi therapy for Alexander DiseaseDaniel Bonthius; Fiscal Year: 2008..The disease is due to an abnormal gene. This research aims to develop a form of gene therapy to prevent and reverse the brain dysfunction of Alexander Disease. [unreadable] [unreadable] [unreadable]..
- Preventive of Bile Acid-Induced Colonic Oxidative DNA DamageClaire Margaret Payne; Fiscal Year: 2010..129 mice) developed in our laboratory;2) NOS-/- k.o./DOC mouse model;3) arginine-enhanced colon tumor ApcMin/+ mouse model developed in our laboratory;4) the AOM mouse model of colon carcinogenesis using A/J mice. ..
- Microchip to Detect Influenza Infection and Type in Nasopharyngeal SwabsCatherine M Klapperich; Fiscal Year: 2010....
- Mechanisms for hypoxic Ca2+ release in pulmonary artery myocytesYong Xiao Wang; Fiscal Year: 2010..The findings from this proposal will enhance our understanding of cellular molecular mechanisms for hypoxic [Ca2+]i rise in PASMCs and associated HPV, and may lead to identify potential novel targets to treat pulmonary hypertension. ..
- Novel Signaling for Ca2+ and Release in Airway MyocytesYong Xiao Wang; Fiscal Year: 2007..6, and/or RyRs are ubiquitously expressed in a variety of cell types, the mechanistic findings from the proposed study will have general biological and pathological significance for various Ca2+-mediated cellular effects. ..
- Cytochrome C Oxidase I:A Biomarker for Colon Cancer RiskClaire Payne; Fiscal Year: 2006..Various molecular and cellular techniques will be used in these studies. ..
- Biomimetic Adhesive for Mineralized TissuesJohn Mitchell; Fiscal Year: 2005..Additionally we will characterize the changes in the interface between tooth and restoration. ..
- A novel therapy for advanced periodontitisEdward Boland; Fiscal Year: 2005..The result of this project will be the preliminary development of a safe, effective and low maintenance treatment for periodontitis which will prevent tooth loss in affected patients. ..
- Dental Composite Resins with Polymer NanofibersHao Fong; Fiscal Year: 2005....
- CONTROLLED-RELEASE SEALANT TO PREVENT SECONDARY CARIESKenneth Anusavice; Fiscal Year: 2004..mutans, site specific levels of S. mutans at the margins of amalgam and composite restorations, and the width of marginal crevices adjacent to amalgam and composite restorations). ..
- 3D Crystal Structure: Vertebrate Mitochondria Complex IIEDWARD BERRY; Fiscal Year: 2005..Finally (e) we want to crystallize a related complex n from an organism amenable to site-directed mutagenesis. ..
- 3D CRYSTALS OF CYTOCHROME REDUCTASE, A MEMBRANE PROTEINEDWARD BERRY; Fiscal Year: 2006..5) Structural studies of functionally relevant mutant bacterial and yeast complexes. ..
- HYBRIDIZED DENTIN: BIOMIMETIC MODELING AND OPTIMIZATIONJayalakshmi Vaidyanathan; Fiscal Year: 2006..Binding studies between the ligands and collagen will be conducted by:1) a novel immunochemical binding assay developed by us; and 2) isothermal titration calorimetry, and related to computed interaction energy values. ..
- Heterogeneity of hypoxic Ca2+ release in pulmonary and *Yong Xiao Wang; Fiscal Year: 2006..The proposed studies are also of fundamental physiological significance with respect to the regulation of Ca2+ release in other cell types. ..
- Determinants of the Durability of Resin-Dentin BondsDavid Pashley; Fiscal Year: 2006..This should provide important new insight into designing more durable resin-dentin bonds that can justify the placement of resin-based posterior composites. ..
- NEUROTERATOGENIC MECHANISM OF LCM VIRUS INFECTIONDaniel Bonthius; Fiscal Year: 2005..The importance of a-DG in influencing the tropism and infectivity of LCMV will be examined by blocking alpha-DG with an antibody prior to exposure of brain slices to LCMV. ..
- Thiol-Ene Polymers as Dental Restorative MaterialsNEIL CRAMER; Fiscal Year: 2006..The compatibility of monomer formulations with filler particles and the properties of filled systems will be evaluated. Biocompatibility of the new dental restorative materials will also be assessed. ..
- CERAMIC WHISKER REINFORCEMENT OF DENTAL COMPOSITE RESINSHUAKUN XU; Fiscal Year: 2002....