Genomes and Genes
Summary: One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.
Publications231 found, 100 shown here
- Ethanol inhibition of porcine bioprosthetic heart valve cusp calcification is enhanced by reduction with sodium borohydrideJeanne M Connolly
Cardiology Research Laboratory, Children s Hospital of Philadelphia, Abramson Research Center, Suite 702, 3615 Civic Center Boulevard, Philadelphia, PA 19104 4318, USA
J Heart Valve Dis 13:487-93. 2004..The study aim was to investigate whether this was due to unreacted aldehyde residues and other reducible compounds resulting from GA cross-linking...
- Cross-linking of human amniotic membrane by glutaraldehydeEberhard Spoerl
Department of Ophthalmology, Universitatsklinikum CGC, Dresden, Germany
Ophthalmic Res 36:71-7. 2004..However, in some diseases the transplant usually dissolves rather quickly and early detachment may occur. Therefore, we tried to stabilize the amniotic transplant by applying glutaraldehyde for collagen cross-linking of the membrane...
- Carbodiimide cross-linked hyaluronic acid hydrogels as cell sheet delivery vehicles: characterization and interaction with corneal endothelial cellsPei Lin Lu
Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan 30013, Republic of China
J Biomater Sci Polym Ed 19:1-18. 2008....
- Cytotoxicity of glutaraldehyde crosslinked collagen/poly(vinyl alcohol) films is by the mechanism of apoptosisJulie E Gough
School of Biomedical Sciences, E Floor, University of Nottingham Medical School, Queen s Medical Centre, Nottingham, NG7 2UH, United Kingdom
J Biomed Mater Res 61:121-30. 2002....
- Glutaraldehyde and glyoxal cross-linked chitosan microspheres for controlled delivery of centchromanK C Gupta
Department of Chemistry, Polymer Research Laboratory, Indian Institute of Technology, Roorkee 247 667, India
Carbohydr Res 341:744-56. 2006..The linear fractional release of centchroman with the square root of time indicated a Fickian behavior of centchroman, and the microspheres also showed zero-order release kinetics for centchroman...
- Effect of desensitizing agents on dentin permeabilityHiroshi Ishihata
Department of Restorative Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan
Am J Dent 22:143-6. 2009..The tested hypothesis was that the products, in spite of different chemical mechanisms were not different at reducing or eliminating flow through dentin discs...
- Effect of desensitizing agents on dentin permeability and dentin tubule occlusionJustine L Kolker
Department of Operative Dentistry, The University of Iowa, Iowa City, Iowa 52242, USA
J Adhes Dent 4:211-21. 2002..The aim of this study was to evaluate: 1) the effect of five dentin desensitizing agents (DDAs) on permeability using hydraulic conductance, and 2) morphological tubule changes with scanning electron microscopy (SEM)...
- Replica of human dentin treated with different desensitizing agents: a methodological SEM study in vitroJose Carlos Pereira
Dentistry, Endodontics and Dental Materials Department, Bauru School of Dentistry, University of Sao Paulo, Brazil
Braz Dent J 13:75-85. 2002..Comparison of the photomicrographs of dentin discs with their respective impressions and resin replicas showed that this technique can reproduce the characteristics of the dentin surface treated with desensitizing agents...
- Efficacy of denture disinfection methods in controlling Candida albicans colonization in vitroRalf Buergers
Department of Prosthetic Dentistry, Regensburg University Medical Centre, Germany
Acta Odontol Scand 66:174-80. 2008..The aim of this study was to rank 10 denture disinfection methods according to their efficacy in reducing Candida albicans (C. albicans) colonization on soft denture relining material...
- Spectroscopic investigation of the function of aqueous 2-hydroxyethylmethacrylate/glutaraldehyde solution as a dentin desensitizerChuangye Qin
National Analytical Research Center of Electrochemistry and Spectroscopy, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China
Eur J Oral Sci 114:354-9. 2006..The function of Gluma as a desensitizer to block dentinal tubules occurs via these two reactions...
- Efficiency and cytotoxicity of resin-based desensitizing agentsJean Camps
Laboratoire IMEB, UFR Odontologie, Marseille, France
Am J Dent 15:300-4. 2002..The tested hypothesis was that their different curing techniques cause variations in efficiency and cytotoxicity...
- The long-term effectiveness of five current desensitizing products on cervical dentine sensitivityI Duran
Department of Periodontology, School of Dentistry, Selcuk University, Konya, Turkey
J Oral Rehabil 31:351-6. 2004....
- Do conventional cleaning and disinfection techniques avoid the risk of endoscopic Helicobacter pylori transmission?M Nurnberg
Oskar Ziethen Hospital, Lichtenberg, Berlin, Germany
Endoscopy 35:295-9. 2003..pylori transmission...
- GI flexible endoscope disinfection: "in use" test comparative studyJosep M Bordas
GI Endoscopy, Motility and Functional Tests, Institut de Malalties Digestives, Institut Malalties Digestives, Hospital Clinic, Facultat de Medicina Universitat de Barcelona, Barcelona, Spain
Hepatogastroenterology 52:800-7. 2005..The "in use" method is adequate for control and for establishing comparisons between different disinfectants...
- Synthesis of cross-linked enzyme aggregates (CLEAs) in CO2-expanded micellar solutionsJing Chen
Center for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China
Colloids Surf B Biointerfaces 48:72-6. 2006..This method has some advantages in applications and can be easily applied to the synthesis of other cross-linked enzyme aggregates...
- Surface fixation of dried blood by glutaraldehyde and peracetic acidG Kampf
Bode Chemie GmbH and Co, Development, Melanchthonstr 27, 22525 Hamburg, Germany
J Hosp Infect 57:139-43. 2004..3%). Our findings underline the potential for blood fixation, not only by glutaraldehyde, but also by peracetic acid, and support the evidence that effective cleaning should precede the chemical disinfection...
- A prospective study of the efficacy of routine decontamination for gastrointestinal endoscopes and the risk factors for failureLinda Bisset
Department of Infectious Diseases and Immunology and The Australian Centre for Hepatitis Virology, The University of Sydney, Australia
Am J Infect Control 34:274-80. 2006..Patient-ready endoscopes were monitored over an 80-week period to determine the efficacy of decontamination procedures in a busy endoscopy center. Decontamination failure was related to patient and procedural parameters...
- Chemical disinfection of hepatitis A virus on environmental surfacesJ N Mbithi
Department of Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ontario, Canada
Appl Environ Microbiol 56:3601-4. 1990..9%; phenolics, iodine-based products, alcohols, and solutions of acetic, peracetic, citric, and phosphoric acids were unable to do so...
- Survival of enveloped and non-enveloped viruses on surfaces compared with other micro-organisms and impact of suboptimal disinfectant exposureR Howie
Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada
J Hosp Infect 69:368-76. 2008..chelonae. Breakthrough survival was detected at 0.1% glutaraldehyde and 0.05% AHP for all organisms tested. Our data emphasise the need for effective cleaning and disinfection in nosocomial settings to prevent pathogen transmission...
- Identification and characterization of an organic solvent tolerance gene in Helicobacter pyloriHung Chuan Chiu
Department of Microbiology, National Taiwan University College of Medicine, Taipei, Taiwan
Helicobacter 12:74-81. 2007..However, some chemical-solvent-tolerant bacteria may survive after incomplete endoscopic disinfection. The goal of this study was to identify glutaraldehyde resistance-related genes in Helicobacter pylori...
- A crosslinked inclusion body process for sialic acid synthesisJozef Nahalka
Institute of Chemistry, Center for Glycomics, Slovak Academy of Sciences, Bratislava, Slovak Republic
J Biotechnol 134:146-53. 2008..The required substrate, N-acetyl-D-mannosamine, was obtained by partially improved alkaline epimerization...
- Molecular detection of methionine in rat brain using specific antibodiesA Amara
Laboratoire d Immunologie et Pathologie, Universite de Bordeaux II, France
Neurosci Lett 185:147-50. 1995..Using purified antibodies diluted at 1/20,000, motoneurons were found to be the most methionine-immunoreactive cell bodies in glutaraldehyde-fixed rat brain sections...
- In vitro dentine permeability evaluation of HEMA-based (desensitizing) products using split-chamber model following in vivo application in the dogI Duran
Selcuk University, School of Dentistry, 42079 Konya, Turkey
J Oral Rehabil 32:34-8. 2005..The Gluma Desensitizing agent provide the more lasting tubule-occluding effect than the other material tested in this model...
- Closing of dentinal tubules by Gluma desensitizerP Schupbach
Institute of Oral Microbiology and General Immunology, University of Zurich, Switzerland
Eur J Oral Sci 105:414-21. 1997..It is concluded that glutaraldehyde can intrinsically block dentinal tubules. The septa in the tubules may counteract the hydrodynamic mechanism for dentinal sensitivity...
- Mechanical and thermal properties of gelatin films at different degrees of glutaraldehyde crosslinkingA Bigi
Department of Chemistry G Ciamician, University of Bologna, Italy
Biomaterials 22:763-8. 2001....
- Treatment of bioprosthetic heart valve tissue with long chain alcohol solution to lower calcification potentialChandrashekar P Pathak
CarboMedics, 1300 East Anderson Lane, Austin, Texas 78752 1793, USA
J Biomed Mater Res A 69:140-4. 2004..These data, taken together, support the notion that treatment of glutaraldehyde-treated tissue with a short and long chain alcohol combination will reduce both extractable phospholipids and the propensity for in vivo calcification...
- Peritoneal regeneration induced by an acellular bovine pericardial patch in the repair of abdominal wall defectsPo Hong Lai
Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan, R O C
J Surg Res 127:85-92. 2005..This study was to evaluate the feasibility of using an acellular bovine pericardium fixed with genipin (AGP) to repair an abdominal wall defect created in a rat model...
- [Immunogenicity of bovine jugular vein conduits treated with different cross-linking methods]Hui Wang
Department of Cardiothoracic Surgery, Second Xiangya Hospital, Central South University, Changsha 410011, China
Zhong Nan Da Xue Xue Bao Yi Xue Ban 30:176-8. 2005..To evaluate the immunogenicity of bovine jugular vein conduits (BJVCs) treated with different cross-linking methods...
- Preparation and characterization of nanoparticles containing trypsin based on hydrophobically modified chitosanChen Guang Liu
Life Science College, Ocean University of China, Qingdao 266003, People s Republic of China
J Agric Food Chem 53:1728-33. 2005..9 mg/mL) was higher than that of pure TR (50.2 mg/mL). However, the thermal stability and optimum temperature of TR immobilized on nanoparticles improved, which make it more attractive in the application aspect...
- Surface fabrication of hollow microspheres from N-methylated chitosan cross-linked with glutaraldehydeXianghong Peng
Department of Chemistry, Wuhan University, Wuhan 430072, China
Langmuir 21:1091-5. 2005..In addition, an anti-infective drug, ofloxacin (Floxin), encapsulated in the microspheres more rapidly released to reach 90 wt % at pH 7.4 within 8 h than at pH 1.2...
- Effects of matrix stabilization when using glutaraldehyde on the material properties of porcine meniscusShawn A Hunter
Noyes Giannestras Biomechanics Laboratories, Department of Biomedical Engineering, 860 Engineering Research Center, University of Cincinnati, Cincinnati, Ohio 45221 0048, USA
J Biomed Mater Res A 67:1245-54. 2003..02% resulted in tissues with material properties no different from the untreated controls. We conclude that minimal concentrations of glutaraldehyde (less than 0.2%) should be used in future studies to preserve normal meniscus properties...
- Adsorption of anionic dyes on chitosan beads. 1. The influence of the chemical structures of dyes and temperature on the adsorption kineticsAntonio R Cestari
Laboratory of Materials and Calorimetry, Departamento de Química CCET, Universidade Federal de Sergipe, CEP 49000 000, Sao Cristovao, Sergipe, Brazil
J Colloid Interface Sci 280:380-6. 2004..Adsorption data of the dyes in relation to the contact time, the chemical structures of the dyes, and temperature were presented and were discussed...
- ADAPT-treated porcine valve tissue (cusp and wall) versus Medtronic Freestyle and Prima Plus: crosslink stability and calcification behavior in the subcutaneous rat modelWilliam M L Neethling
Fremantle Heart Institute and University of Western Australia, Department of Cardiothoracic, Fremantle Hospital, Western Australia
J Heart Valve Dis 13:689-96; discussion 696. 2004....
- Preparation and characterisation in simulated body conditions of glutaraldehyde crosslinked chitosan membranesR M Silva
Department of Polymer Engineering, University of Minho, Campus de Azurem, 4800 058 Guimaraes, Portugal
J Mater Sci Mater Med 15:1105-12. 2004..Weight loss measurements showed that the developed membranes degrade slowly up to 60 days. Cytotoxicity screening, using cell culture tests, showed that eventually such materials could be adequate for use in biomedical applications...
- Thermal dehydration treatment and glutaraldehyde cross-linking to increase the biostability of collagen-chitosan porous scaffolds used as dermal equivalentLie Ma
Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
J Biomater Sci Polym Ed 14:861-74. 2003..These results suggest that the GA-treated scaffold has an increased biostability and excellent biocompatibility. It can be a potential candidate for skin-tissue engineering...
- Viscoelastic characterizations of acellular dermal matrix (ADM) preparations for use as injectable implantsHsiu O Ho
Graduate Institute of Pharmaceutical Sciences, College of Pharmacy, Taipei Medical University, 250 Wu Hsing Street, Taipei, Taiwan, Republic of China
J Biomed Mater Res A 70:83-96. 2004..Similarly, viscoelastic characteristics of the ADM preparations examined were also so sensitive to temperature that the persistence of ADM preparations after implantation at body temperature would deteriorate...
- Immunoelectron microscopy study of polyamines using a newly prepared monoclonal antibody against spermidine: use of a mixture of glutaraldehyde and paraformaldehyde as a cross-linking agent in the preparation of the antigenToshio Tanabe
Diagnostic Agent Development Office, Nippon Kayaku, 1 11 2 Fujimi, Chiyoda ku, Tokyo 102 8172
J Biochem 135:501-7. 2004..These results are in complete agreement with the results obtained by our recent ICC method using another mAb (ASPM-29) produced against GA-conjugated Spm...
- A novel in situ gel for sustained drug delivery and targetingSudipta Ganguly
Department of Pharmacy Sciences, School of Pharmacy and Health Professions, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA
Int J Pharm 276:83-92. 2004..Inclusion of GMO enhanced the mucoadhesive property of chitosan by three- to sevenfold. This novel in situ gel system can be useful in the sustained delivery of drugs via oral as well as parenteral routes...
- [Methods for the pre-treatment of biological tissues for vascular scaffold]Xixun Yu
Institute of Biomedical Engineering, West Chin Center of Medical Sciences, Sichuan University, Chengdu 610041, China
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 21:476-81. 2004..Meanwhile, dye-mediated photooxidation crosslink is also a promising pre-treatment which should be widely applied in vascular scaffold...
- An amperometric acetylthiocholine sensor based on immobilization of acetylcholinesterase on a multiwall carbon nanotube-cross-linked chitosan compositeDan Du
Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, Central China Normal University, Wuhan, 430079, China
Anal Bioanal Chem 387:1059-65. 2007..10 micromol L(-1). Fabrication reproducibility of the sensor was good and the stability was acceptable. The sensor is a promising new tool for characterization of enzyme inhibitors and for pesticide analysis. Abstract...
- Production of lipase in a fermentor using a mutant strain of Corynebacterium species: its partial purification and immobilizationNityananda Roy
Department of Food Technology and Biochemical Engineering, Jadavpur University, Kolkata 700 032, India
Indian J Exp Biol 42:202-7. 2004..1 micromol/min and 14.7% respectively. Ca2+ (5 mM) was found to be stimulator for enzyme activity. Immobilized lipase retained 68.18% of the original activity when stored for 40 days...
- Mechanical properties of electrospun fibrinogen structuresMichael C McManus
Department of Surgery, Virginia Commonwealth University, Richmond, 23298 0230, USA
Acta Biomater 2:19-28. 2006..In conclusion, the mechanical characteristics of electrospun fibrinogen strongly support its potential use as a tissue engineering scaffold or wound dressing...
- Synthesis, characterization and immunogenicity of silk fibroin-L-asparaginase bioconjugatesYu Qing Zhang
Silk Biotechnology Laboratory, School of Life Science, Soochow University, No 1 Shizi Street, Suzhou, Jiangsu 215006, PR China
J Biotechnol 120:315-26. 2005..SF-ASNase bioconjugates could overcome the common shortcomings of the native form. Therefore, the modified ASNase coupled with silk fibroin has the potential values of being studied and developed as a new bioconjugate drug...
- Preparation and properties of invertase immobilized on a poly(maleic anhydride-hexen-1) membraneHidayet Mazi
Department of Chemistry, Faculty of Science, Hacettepe University, 06532, Ankara, Turkey
J Biomater Sci Polym Ed 17:821-35. 2006..Immobilization improved the pH stability of the enzyme, as well as its temperature stability. Immobilized samples obtained were stable and could be used many times over a period of 2 months without considerable activity loss...
- Glutaraldehyde cross-linking of lipases adsorbed on aminated supports in the presence of detergents leads to improved performanceGloria Fernandez-Lorente
Departamento de Biocatalisis, Instituto de Catalisis CSIC, Campus UAM, Cantoblanco, Madrid, Spain
Biomacromolecules 7:2610-5. 2006..This strategy seems to be of general use to improve the lipase activity to be used in macroaqueous media...
- A multi-step approach in anti-calcification of glutaraldehyde-preserved bovine pericardiumW M L Neethling
Fremantle Heart Institute, Fremantle Hospital, School of Surgery and Pathology, University of Western Australia, Fremantle, Western Australia
J Cardiovasc Surg (Torino) 47:711-8. 2006....
- Cross-linking chitosan nanofibersJessica D Schiffman
Department of Materials Science and Engineering, Drexel University, Philadelphia, Pennsylvania 19104, USA
Biomacromolecules 8:594-601. 2007....
- Preparation and characterization of glutaraldehyde cross-linked O-carboxymethylchitosan microspheres for controlled delivery of pazufloxacin mesilateYan fei Liu
College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China
Int J Biol Macromol 41:87-93. 2007..The release profiles of PM from OCMC microspheres were found to be biphasic with a burst release followed by a gradual release phase, and followed the Higuchi matrix model...
- Calcium alginate entrapped preparations of Aspergillus oryzae beta galactosidase: its stability and applications in the hydrolysis of lactoseToshiba Haider
Department of Biochemistry, Faculty of Life Sciences, Aligarh Muslim University, Aligarh 202002, UP, India
Int J Biol Macromol 41:72-80. 2007..This entrapped crosslinked concanavalin A-beta galactosidase complex retained 95% activity after seventh repeated use and 93% of its original activity even after 2 months storage at 4 degrees C...
- Covalent attachment of cholesterol oxidase and horseradish peroxidase on perlite through silanization: activity, stability and co-immobilizationSeyed Fakhreddin Torabi
Department of Biotechnology, University College of Science, University of Tehran, Tehran, Iran
J Biotechnol 131:111-20. 2007..Immobilized COD showed inhibition in its activity at high cholesterol concentration which was not reported for soluble COD before. Co-immobilized enzymes retained 65% of its initial activity after 20 consecutive reactor batch cycles...
- Monolithic macroporous albumin/chitosan cryogel structure: a new matrix for enzyme immobilizationMartin Hedström
Department of Biotechnology, Lund University, P O Box 124, 22100, Lund, Sweden
Anal Bioanal Chem 390:907-12. 2008..The low hydraulic resistance of the matrix allowed for the development of a generic, high-performance online protein digestion system utilizing the wall-bound proteases...
- Two biosensors for phenolic compounds based on mushroom (Agaricus bisporus) homogenate: comparison in terms of some important parameters of the biosensorsMustafa Teke
Faculty of Science and Arts, Chemistry Department, Mugla University, Mugla, Turkiye
Prep Biochem Biotechnol 38:51-60. 2008..The aim of the study was to compare the two biosensors in terms of their repeatability and thermal, pH, and operational stability; also, the linear ranges of the two biosensors were compared with each other...
- Histological evaluation of biocompatibility of lyophilized bovine pericardium implanted subcutaneously in ratsMarina J S Maizato
Bioengineering Division Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
Artif Organs 32:268-71. 2008..The implanted lyophilized samples presented a trend for a reduced inflammatory reaction. Lyophilization of the bovine pericardium does not seem to increase the above listed tissue reaction...
- Preparation and characterization of uniform-sized chitosan microspheres containing insulin by membrane emulsification and a two-step solidification processLian Yan Wang
State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, P O Box 353, Beijing 100080, China
Colloids Surf B Biointerfaces 50:126-35. 2006..5-4.0, the molar ratio of amino group of chitosan to aldehyde group of glutaraldehyde was 1:1 and the crosslinking time of glutaraldehyde was 60 min...
- Reduction of flatus-inducing factors in soymilk by immobilized alpha-galactosidaseDhananjay S Kulkarni
Department of Biochemistry, Gulbarga University, Gulbarga 585 106, Karnataka, India
Biotechnol Appl Biochem 45:51-7. 2006..The immobilized enzyme was used repeatedly ten times without any change in the performance of the immobilized enzyme in fluidized-bed reactor. The results obtained are of considerable interest for industrial purposes...
- Reduction of calcification of carbodiimide-processed heart valve tissue by prior blocking of amine groups with monoaldehydesFrank Everaerts
Medtronic Inc, Minneapolis, USA
J Heart Valve Dis 15:269-77. 2006..Failure of implanted bioprostheses due to calcification is a commonly occurring phenomenon. In order to prevent calcification, many alternative cross-linking methods to glutaraldehyde (GA) have been developed and evaluated...
- Cell-free xenogenic vascular grafts fixed with glutaraldehyde or genipin: in vitro and in vivo studiesYen Chang
Division of Cardiovascular Surgery, Veterans General Hospital Taichung and College of Medicine, National Yang Ming University, Taipei, Taiwan, ROC
J Biotechnol 120:207-19. 2005..Nevertheless, the H-A-GP graft was superior to the H-A-GA graft in completeness of endothelialization on its luminal surface, and thus precluded thrombus formation...
- Diamine-extended glutaraldehyde- and carbodiimide crosslinks act synergistically in mitigating bioprosthetic aortic wall calcificationPeter Zilla
Department of Cardiothoracic Surgery, Cape Heart Centre, University of Cape Town, South Africa
J Heart Valve Dis 14:538-45. 2005....
- An in vivo study of tricalcium phosphate and glutaraldehyde crosslinking gelatin conduits in peripheral nerve repairMing Hong Chen
Institute of Biomedical Engineering, National Taiwan University, No 1, Sec 1, Jen Ai Road, Taipei, Taiwan
J Biomed Mater Res B Appl Biomater 77:89-97. 2006..The difference reached a significant level at 24 weeks. Thus, the histomorphometric, electrophysiologic, and functional assessments demonstrate that GTG can be a candidate for peripheral nerve repair...
- Preparation of cross-linked chitosan microspheres by spray drying: effect of cross-linking agent on the properties of spray dried microspheresK G H Desai
School of Life Sciences and Biotechnology, Korea University, Sungbuk Ku, Seoul, South Korea
J Microencapsul 22:377-95. 2005..Release of the drug from chitosan-TPP, chitosan-FA and chitosan-GA matrices followed Fick's law of diffusion...
- Structural elements of bulk chromatin within metaphase chromosomesJuan Manuel Caravaca
Departament de Bioquimica i Biologia Molecular, Facultat de Ciencies, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
Chromosome Res 13:725-43. 2005....
- Adsorption of lipase on hollow fiber membrane chipsMarwan M Shamel
Terengganu Advanced Technical Institute, Jalan Panchor, Teluk Kalong, Kemaman, Terengganu Darul Iman, Malaysia
Artif Cells Blood Substit Immobil Biotechnol 33:423-33. 2005..However, increasing the concentration of the cross-linking agent has a low effect on the amount of lipase adsorbed...
- pH-sensitive behavior of two-component hydrogels composed of N,O-carboxymethyl chitosan and alginateFwu Long Mi
Division of Applied Chemistry, Department of Applied Science, Chinese Naval Academy, 669 Jiun Shiaw Road, Kaohsiung, Taiwan 813, ROC
J Biomater Sci Polym Ed 16:1333-45. 2005..The aforementioned results indicated that the swelling behaviors and drug-release profiles of these test hydrogels are significantly different due to their distinct cross-linking structures...
- Crosslinked chitosan implants as potential degradable devices for brachytherapy: in vitro and in vivo analysisAbdel Kareem Azab
Department of Pharmaceutics, The Hebrew University of Jerusalem, School of Pharmacy, P O Box 12065, Jerusalem 91120, Israel
J Control Release 111:281-9. 2006..It is concluded that hydrogels made of crosslinked Ct are potential novel, safe, degradable devices for brachytherapy...
- Structural requirements for stabilization of vascular elastin by polyphenolic tanninsJason C Isenburg
Cardiovascular Implant Research Laboratory, Department of Bioengineering, Clemson University, 501 Rhodes Engineering Research Center, Clemson, SC 29634, USA
Biomaterials 27:3645-51. 2006....
- An amperometric enzyme electrode for creatine determination prepared by the immobilization of creatinase and sarcosine oxidase in poly(vinylferrocenium)Pinar Esra Erden
Department of Chemistry, Faculty of Science, Ankara University, Ankara, Turkey
Artif Cells Blood Substit Immobil Biotechnol 34:223-39. 2006..5, 37 degrees C, 2.5:1 (CI:SO) and 0.05 M, respectively. The stability and reproducibility of the enzyme electrode have been also studied...
- Preparation and characterization of cross-linked enzyme aggregates (CLEA) of subtilisin for controlled release applicationsK Sangeetha
Chemical Science and Technology Division, Regional Research Laboratory CSIR, Trivandrum 695019, India
Int J Biol Macromol 43:314-9. 2008..Application of these pH-sensitive beads for the controlled release of subtilisin in vitro was studied and found to be a feasible strategy...
- Role of elastin in pathologic calcification of xenograft heart valvesMichael T Bailey
Department of Bioengineering, 501 Rhodes Engineering Research Center, Clemson University, Clemson, South Carolina 29634, USA
J Biomed Mater Res A 66:93-102. 2003..Our results also demonstrate the importance of studying elastin-oriented calcification in decellularized elastin-rich aortic matrices currently used in tissue-engineering applications...
- Inflammatory and immune processes: the neglected villain of bioprosthetic degeneration?P Human
Department of Cardiothoracic Surgery, Cape Heart Centre, University of Cape Town Medical School, Cape Town, South Africa
J Long Term Eff Med Implants 11:199-220. 2001..Finally we present evidence for a role of circulating antibodies in bioprosthesis calcification...
- Glutaraldehyde-fixed kangaroo aortic wall tissue: histology, crosslink stability and calcification potentialW M L Neethling
Fremantle Heart Institute and University of Western Australia, Fremantle Hospital, Fremantle, Western Australia
J Biomed Mater Res B Appl Biomater 66:356-63. 2003..The reduced calcification potential could result in improved long-term durability of stentless kangaroo heart valves as bioprostheses...
- Detoxification on top of enhanced, diamine-extended glutaraldehyde fixation significantly reduces bioprosthetic root calcification in the sheep modelAmeli E Trantina-Yates
Department of Cardiothoracic Surgery, Cape Heart Centre, University of Cape Town, South Africa
J Heart Valve Dis 12:93-100; discussion 100-1. 2003..The study aim was to demonstrate the combined effect of all three treatments in a circulatory sheep model...
- Degeneration of bioprosthetic heart valve cusp and wall tissues is initiated during tissue preparation: an ultrastructural studyDan T Simionescu
Cardiovascular Implant Research Laboratory, Department of Bioengineering, Clemson University, Clemson, South Carolina 29634, USA
J Heart Valve Dis 12:226-34. 2003....
- Stress state during fixation determines susceptibility to fatigue-linked biodegradation in bioprosthetic heart valve materialsSean D Margueratt
School of Biomedical Engineering, Dalhousie University, 5981 University Avenue, Halifax, Nova Scotia, Canada B3H3J5
Biomed Sci Instrum 38:145-50. 2002..There were significant decreases in the mechanical properties and an increase in the amount of collagen solubilized with increased exposure to fatigue cycling...
- Biocompatibility study of biological tissues fixed by a natural compound (reuterin) produced by Lactobacillus reuteriHsing Wen Sung
Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan
Biomaterials 23:3203-14. 2002..Additionally, reuterin fixation may inhibit tissue calcification as compared to glutaraldehyde fixation. These observations implied that the biocompatibility of the reuterin-fixed tissue is superior to the glutaraldehyde-fixed tissue...
- Feasibility study using a natural compound (reuterin) produced by Lactobacillus reuteri in sterilizing and crosslinking biological tissuesChiun Nan Chen
Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan 30013
J Biomed Mater Res 61:360-9. 2002..In conclusion, the results obtained in this study indicate that reuterin is an effective agent in the sterilization and fixation of biological tissues...
- Behavior and properties of neat and filled gelatinsM Usta
Department of Materials Science and Engineering, Gebze Institute of Technology, Kocaeli, Turkey 41400
Biomaterials 24:165-72. 2003..The cross-linking led to different coordinations following the formaldehyde vs. the glutaraldehyde treatments...
- Influence of species, environmental factors, and tissue cellularity on calcification of porcine aortic wall tissueB Meuris
Department of Cardiac Surgery, Katholieke Universiteit Leuven, Leuven, Belgium
Semin Thorac Cardiovasc Surg 13:99-105. 2001..will be necessary to avoid the inflammation leading to elastolysis and consequent calcification of elastic fibers...
- In vitro evaluation of a chitosan membrane cross-linked with genipinF L Mi
Department of Mathematics, Physics and Chemistry, Chinese Naval Academy, Kaohsiung, Taiwan, ROC
J Biomater Sci Polym Ed 12:835-50. 2001..The drug-release characteristics of the genipin-cross-linked chitosan membrane are currently under investigation...
- High-level expression, functional reconstitution, and quaternary structure of a prokaryotic ClC-type chloride channelM Maduke
Department of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, Massachusetts 02254 9110, USA
J Gen Physiol 114:713-22. 1999..Cross-linking studies argue that EriC is a homodimer in both detergent micelles and reconstituted liposomes, a conclusion corroborated by gel filtration and analytical sedimentation experiments...
- Disulfide-mediated oligomerization of Peripherin/Rds and Rom-1 in photoreceptor disk membranes. Implications for photoreceptor outer segment morphogenesis and degenerationC J Loewen
Department of Biochemistry, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
J Biol Chem 275:5370-8. 2000..Peripherin/Rds containing core complexes interact through specific intermolecular disulfide bonds to form oligomers which may play a crucial role in photoreceptor disc morphogenesis and retinal degenerative diseases...
- Improved calcification resistance and biocompatibility of tissue patch grafted with sulfonated PEO or heparin after glutaraldehyde fixationW K Lee
Korea Institute of Science and Technology, Biomaterials Research Center, P.O. Box 131, Cheongnyang, Seoul 130-650, Korea
J Biomed Mater Res 58:27-35. 2001..This simple modification method may be useful for calcification-resistant and blood-compatible tissue patches for cardiovascular implants...
- Collagen-chitosan polymeric scaffolds for the in vitro culture of human epidermoid carcinoma cellsN Shanmugasundaram
Biomaterials Division, Central Leather Research Institute, Adyar, Madras, India
Biomaterials 22:1943-51. 2001..The results of the above studies suggest that the scaffolds prepared from collagen and chitosan can be utilized as a substrate to culture HEp-2 cells and can also be used as an in vitro model to test anticancerous drugs...
- A natural compound (reuterin) produced by Lactobacillus reuteri for biological-tissue fixationHsing Wen Sung
Department of Chemical Engineering, National Tsing Hua University, Hsinchu, 30013, Taiwan
Biomaterials 24:1335-47. 2003..However, after fixation, it was noted that the reuterin-fixed tissue has comparable free-amino-group content, denaturation temperature, tensile strength, and resistance against enzymatic degradation as the glutaraldehyde-fixed tissue...
- Efficacy of high-level disinfectants for reprocessing GI endoscopes in simulated-use testingR L Foliente
Division of Gastroenterology and Department of Microbiology, Loma Linda University School of Medicine, California, USA
Gastrointest Endosc 53:456-62. 2001..Several agents are currently approved by the FDA, but published data on their relative efficacies against mycobacteria are lacking. The objective of this study was to determine the efficacy of these agents for high-level disinfection...
- Blue-light induced interaction of LOV domains from Chlamydomonas reinhardtiiRoger J Kutta
Institut fur Physikalische und Theoretische Chemie, Universitat Regensburg, Universitatsstrasse 31, 93053 Regensburg, Germany
Chembiochem 9:1931-8. 2008..A model is presented that accounts for a blue-light-driven change in the quaternary structure of the LOV1 domain and gives hints to the molecular basis of light activation and regulation in LOV-containing proteins...
- Results of therapy and changing prognosis of multiple myeloma during the last 40 years in the region of North and Middle Moravia: group of 562 patientsVlastimil Scudla
3rd Department of Medicine, Palacky University Hospital, Olomouc, Czech Republic
Hematol J 4:351-7. 2003..The aim of this study was the retrospective assessment of therapy results and the changing prognosis of multiple myeloma (MM) patients from the Middle and North Moravia region of the Czech Republic during the last 40 years...
- Circular dichroism analysis of penicillin G acylase covalently immobilized on silica nanoparticlesBertolt Kranz
Institute for Technical Chemistry, Water Technology and Geotechnology, Forschungszentrum Karlsruhe GmbH, P O Box 3640, 76021 Karlsruhe, Germany
J Colloid Interface Sci 316:413-9. 2007..9 to 55.8 mg/g. Because of the fact that we found no major changes in the secondary structure, diffusion limitation seems to be the main reason for the decline of the specific activity...
- Non-enzymatic posttranslational modifications of bovine serum albumin by oxo-compounds investigated by chromatographic and electrophoretic methodsKaterina Mikulikova
Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 14220 Prague 4, Czech Republic
J Chromatogr B Analyt Technol Biomed Life Sci 815:315-31. 2005....
- Autoclave sterilization of instruments used on women with cervical neoplasia is an effective method of eradicating residual human papillomavirus DNA: a polymerase chain reaction-based evaluationJacob M Estes
Division of Gynecologic Oncology, The University of Alabama Birmingham, Birmingham, AL 35249, USA
J Low Genit Tract Dis 11:12-7. 2007..To determine whether autoclave sterilization eradicates human papillomavirus (HPV) DNA on specula and instruments used to treat women with cervical neoplasia...
- A survey of the appropriate use of antiseptic agents in the operating room of several key health care facilities. A comparison between surveys in 2000 and 2004T Shiraishi
Division of Pharmacy, Yamagata University Hospital, Yamagata 990 9585, Japan
Dermatology 212:15-20. 2006..Especially, amphoteric detergents and glutaral products showed significant reductions in the total amount used in the 6 hospitals, by 94.8 and 96...
- Consumer exposure to biocides--identification of relevant sources and evaluation of possible health effectsStefan Hahn
Fraunhofer Institute for Toxicology and Experimental Medicine, Department Chemical Risk Assessment, Nikolai Fuchs Str, 1, 30625 Hanover, Germany
Environ Health 9:7. 2010....
- Rapid communication: effects of Steris 1 sterilization and Cidex ortho-phthalaldehyde high-level disinfection on durability of new-generation flexible ureteroscopesJose Benito A Abraham
Department of Urology, University of California Irvine, Orange, California 92868, USA
J Endourol 21:985-92. 2007..We prospectively studied the effects of Steris 1 sterilization and Cidex ortho-phthalaldehyde (OPA) high-level disinfection (HLD) on the image quality, physical structure, and deflective properties of two new flexible ureteroscopes...
- [The immune enhancement of the C3 to the Escherichia coli vaccine]Xue Yun Ma
Animal Science and Veterinary Medicine College of Shandong Agricultural University, Tai an 271018, China
Wei Sheng Wu Xue Bao 46:812-5. 2006C3b was separated and purified from the SPF chicken serum. It was linked with E. coli antigen by the glutaral. 11 days aged SPF chicken were immunized by the complex antigen and the chickens of control group were immunised by the FCA- E...
- Effect of peracetic acid and aldehyde disinfectants on biofilmN Henoun Loukili
Service de Gestion du Risque Infectieux, University Hospital of Lille, Lille, France
J Hosp Infect 58:151-4. 2004..Users should be concerned about the efficiency of the cleaning stage of medical devices, and when choosing a PAA product, non-fixing ability should be considered in addition to antimicrobial activity...
- Eimeria bovis meront I-carrying host cells express parasite-specific antigens on their surface membraneAhmed Ibrahem I Badawy
Institute of Parasitology, Justus Liebig University Giessen, Rudolf Buchheim Str 2, 35392, Giessen, Germany
Vet Res Commun 34:103-18. 2010..Although the function of EbHCSAg is still unknown, results of this study might suggest an involvement in the development of protective immunity against E. bovis infections...
- Acute glutaraldehyde mucosal injury of the upper aerodigestive tract due to damage to the working channel of an endoscopePriya D Krishna
Division of Laryngology, Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Ann Otol Rhinol Laryngol 119:150-4. 2010..This report details the clinical course of 2 patients who suffered acute glutaraldehyde exposure during office injection procedures...
- Entrapment in E. coli improves the operational stability of recombinant beta-glycosidase CelB from Pyrococcus furiosus and facilitates biocatalyst recoveryThomas Kamrat
Research Centre Applied Biocatalysis, Petersgasse 14, c o Institute of Biotechnology and Biochemical Engineering, Graz University of Technology, Petersgasse 12, A 8010 Graz, Austria
J Biotechnol 129:69-76. 2007..Entrapment facilitated downstream processing of CelB and biocatalyst recovery in repeated batchwise conversions of lactose at elevated temperatures...
- The effect of sterilization methods on the light transmission characteristics and structure of light-curing tipsA Kakaboura
Department of Operative Dentistry, School of Dentistry, University of Athens, Athens, Greece
J Oral Rehabil 31:918-23. 2004..Water-steam autoclave is safer than the 0.2% sodium dicloroisocyanorate and 2% glutaraldehyde chemical sterilization agents regarding the light transmission characteristics and the structure of the light-curing tips...
- Glyoxal is an important allergen for (medical care) cleaning staffW Uter
Information Network of Departments of Dermatology IVDK, Georg August University, Department of Dermatology, Gottingen, Germany
Int J Hyg Environ Health 204:251-3. 2001..In conclusion, glyoxal should be tested in all patients with contact dermatitis working in occupations with possible exposure to respective disinfecting/cleaning agents...
- An evaluation of Cidex OPA (0.55% ortho-phthalaldehyde) as an alternative to 2% glutaraldehyde for high-level disinfection of endoscopesR P D Cooke
Department of Infection Prevention and Control, District General Hospital, Eastbourne, East Sussex BN2 2UD, UK
J Hosp Infect 54:226-31. 2003..The increased cost of changing to Cidex OPA was estimated as pound 7691 per annum. Staining of washer-disinfectors was of concern as it proved very difficult to remove...
- Glutardialdehyde induced fluorescence technique (GIFT): a new method for the imaging of platelet adhesion on biomaterialsR D Frank
IZKF Biomat University Hospital RWTH Aachen, Pauwelsstr 30, 52057 Aachen, Germany
J Biomed Mater Res 52:374-81. 2000..In conclusion, GIFT is a valid, rapid, and simple method for the quantitative determination of platelet/material interactions intended for the evaluation of thrombogenicity of biomaterials surfaces...
- Human Sensory Irritation From Volitile Organic CompoundsWilliam Cain; Fiscal Year: 2006..F) The effect of inflammation upon chemesthetic sensitivity. G) Through measurement of the NMP, confirmation of the peripheral basis for a) temporal phenomena, b) differences in potency, and c) effects of inflammation. ..
- A screen for small molecule inhibitors of soluble Abeta oligomer assemblyHarry LeVine; Fiscal Year: 2007..Anti-oligomer compounds could potentially block the cognitive impairment symptoms that oligomers elicit in animal models and interfere with the progression of Alzheimer's disease. [unreadable] [unreadable] [unreadable]..
- Nanotube Reagentless Proteomic ArraysMichael Wilson; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Enhanced Capillary DNA SequencingPhilip Serwer; Fiscal Year: 2004..Each adaptation will help solve a current genomic problem, for example, either closing of a partially assembled genome sequence or performing high accuracy analysis of mutations. ..
- REGULATION OF EXTRACELLULAR SUPEROXIDE DISMUTASE BY PROTRussell Bowler; Fiscal Year: 2004..This will not only define new aspects of the pathogenesis and regulation of vascular tone and inflammation, but can open new approaches to pharmacologically control these events. ..
- Rapid Immunoassays for Detecting Pathogenic BacteriaMichael Wilson; Fiscal Year: 2004..EIC has a commercial path for assay technology through in-house manufacturing, sale of electrochemical assays and hand-held assay readers, and out-licensing of our multianalyte immunoassay technology. ..
- Determinants of the Durability of Resin-Dentin BondsDavid Pashley; Fiscal Year: 2006..This should provide important new insight into designing more durable resin-dentin bonds that can justify the placement of resin-based posterior composites. ..
- IRIDIUM OXIDE PROTEIN MICROARRAYSMichael Wilson; Fiscal Year: 2002..In Phase II, higher density protein arrays suitable for integration into automated, high-throughput microfluidic delivery systems and fluorescent analyzers will be developed. ..
- Assembly Visualized Routine Flourescence MicroscopyPhilip Serwer; Fiscal Year: 2008..Applications are anticipated in the analysis of the assembly of disease-causing viruses and determining pathways of oncogenesis. ..
- DNA Packaging MotorsPhilip Serwer; Fiscal Year: 2005..Analysis of bacteriophage DNA packaging motors is expected to provide a basis for understanding the role of motors in disease, especially disease caused by a virus that has a DNA packaging motor. ..
- Rapid Quantitative Point-of-Care Cardiac Marker TestMichael Wilson; Fiscal Year: 2005..EIC has a clear commercial path for assay technology through in-house manufacturing, sale of electrochemical assays and hand-held assay readers, and out-licensing of our multianalyte immunoassay technology. ..
- SOLUTE AND FLUID TRANSPORT ACROSS THE CONJUNCTIVAOSCAR CANDIA; Fiscal Year: 2002..Based on this model, he will devise protocols to modify and possibly reverse the secretory/absorptive properties of the tissue. ..
- Micro-and nano-mechanical and chemical guidance of neuronsChristine Schmidt; Fiscal Year: 2008..unreadable] [unreadable]..
- Fabrication of Novel Biomimetic Polymers Using Combinatorial Peptide ScreeningChristine Schmidt; Fiscal Year: 2008..unreadable] [unreadable]..
- Mechanically Stable Blood SubstitutesAndre Francis Palmer; Fiscal Year: 2010..The proposed work is both innovative and significant, because novel LEAcHb hybrid vesicles with engineered structural and mechanical characteristics will be created for use as an artificial blood substitute. ..
- Nuclease-Resistant Aptamers for Anthrax OpsonizationJohn Bruno; Fiscal Year: 2004..Such shielded aptamers could even be used in inhalers to enhance alveolar macrophage phagocytosis. ..
- Measurement of Fluid Flow Across the Ocular Ciliary BodyOSCAR CANDIA; Fiscal Year: 2006..abstract_text> ..
- Nuclease-Resistant Aptamers to Botox and Anthrax ToxinsJohn Bruno; Fiscal Year: 2004..Such reagents could also be used in environmental biosensors or diagnostic test kits for detection of BOTOX and anthrax toxins in body fluids or environmental samples. ..
- MINORITY PREDOCTORAL FELLOWSHIP PROGRAMLAURA NGWENYA; Fiscal Year: 2005..It has been established that cognitive decline occurs with age. This proposed investigation will determine if there are changes in adult cell genesis that could be important in the neurobiological basis of age-related cognitive decline. ..
- ANTIBODY MICROARRAY FOR DETECTION OF TUMOR MARKERSMichael Wilson; Fiscal Year: 2005..The Phase II will focus on developing a robust, reliable and reproducible assaying system. ..
- Enhanced O2 Delivery to C3A HepatocytesAndre Palmer; Fiscal Year: 2009..The knowledge gained from this study is expected to be of benefit in the design of hepatocyte containing HF bioreactors for use as potential BLADs. ..
- ENHANCED DURABILITY OF BIOPROSTHETIC HEART VALVESMichael Sacks; Fiscal Year: 2004..Determine how chemical treatment alters cuspal layer micromechanics. 2. Quantify PBHV cuspal deformation during the cardiac cycle. 3. Determine how long-term cyclic fatigue alters PBHV later structure and mechanical properties. ..
- Fluid Movement across Conjunctiva: Stimulation and RegulationOSCAR CANDIA; Fiscal Year: 2007..These studies may provide the groundwork for the design of future treatment modalities for dry-eye syndromes. ..