tromethamine

Summary

Summary: An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)

Top Publications

  1. ncbi Evaluation of carboprost tromethamine in the treatment of cyclophosphamide-induced hemorrhagic cystitis
    L A Levine
    Section of Urology, University of Chicago, IL 60637
    Cancer 66:242-5. 1990
  2. ncbi Comparison of oral nonsteroidal analgesic and intrauterine local anesthetic for pain relief in uterine fractional curettage: a randomized, double-blind, placebo-controlled trial
    Olus Api
    Department of Obstetrics and Gynecology, Dr Lutfi Kirdar Kartal Teaching and Research Hospital, Acelya Sok No 12 2, Dragos Kartal, Istanbul, Turkey
    Am J Obstet Gynecol 203:28.e1-7. 2010
  3. ncbi Effect of pH value of freeze-drying solution on the chromosome integrity and developmental ability of mouse spermatozoa
    Takehito Kaneko
    The Institute for Biogenesis Research, Department of Anatomy and Reproductive Biology, John A Burns School of Medicine, University of Hawaii, Honolulu, Hawaii 96822, USA
    Biol Reprod 68:136-9. 2003
  4. ncbi Analgesic efficacy and safety of nonpreserved ketorolac tromethamine ophthalmic solution following radial keratotomy. Ketorolac Radial Keratotomy Study Group
    R W Yee
    University of Texas at Houston, 77030, USA
    Am J Ophthalmol 125:472-80. 1998
  5. ncbi Prophylactic and therapeutic carboprost tromethamine bladder irrigation in rats with cyclophosphamide-induced hemorrhagic cystitis
    D M Kranc
    Department of Surgery Urology, University of Chicago, Illinois
    J Urol 148:1326-30. 1992
  6. ncbi Entry of tromethamine into the cerebrospinal fluid of humans after cerebrovascular events
    R Nau
    Department of Neurology, Georg August Universitat, Gottingen, Germany
    Clin Pharmacol Ther 66:25-32. 1999
  7. ncbi The treatment of acidosis in acute lung injury with tris-hydroxymethyl aminomethane (THAM)
    R H Kallet
    Department of Anesthesia and Division of Pulmonary and Critical Care Medicine, University of California, San Francisco at San Francisco General Hospital, San Francisco, California 94110, USA
    Am J Respir Crit Care Med 161:1149-53. 2000
  8. ncbi The effects on platelet aggregation and prostanoid biosynthesis of two parenteral analgesics: ketorolac tromethamine and dipyrone
    G Geisslinger
    Department of Experimental and Clinical Pharmacology, University of Graz, Austria
    Thromb Haemost 76:592-7. 1996
  9. ncbi Treating intraoperative hyperchloremic acidosis with sodium bicarbonate or tris-hydroxymethyl aminomethane: a randomized prospective study
    Markus Rehm
    Klinik fur Anaesthesiologie, Ludwig Maximilians Universitat, Klinikum Grosshadern, Marchioninistrasse 15, D 18377 Munich, Germany markus rehm ana med uni muenchen de
    Anesth Analg 96:1201-8, table of contents. 2003
  10. ncbi Investigation of novel quantum dots/proteins/cellulose bioconjugate using NSOM and fluorescence
    Peng Zhang
    Department of Chemistry, New Mexico Institute of Mining and Technology, Socorro, New Mexico 87801, USA
    J Fluoresc 16:349-53. 2006

Research Grants

  1. Structure and Dynamics of RNA
    Arthur Pardi; Fiscal Year: 2006
  2. Purchase of 800 MHz NMR Spectrometer
    Arthur Pardi; Fiscal Year: 2002
  3. Structure and Dynamics of RNA and Protein-RNA Complexes
    Arthur Pardi; Fiscal Year: 2008
  4. Structure-Function Studies of Ribozyme and RNA
    Arthur Pardi; Fiscal Year: 2008
  5. Structure Function Studies of DNA Mismatch Repair
    Dorothy A Erie; Fiscal Year: 2010
  6. Identification of Alcohol Binding Site(s) in Protein Kinase C Epsilon
    Joydip Das; Fiscal Year: 2007
  7. BIOPHYSICAL AND SCANNING FORCE MICROSCOPY STUDIES
    DOROTHY ERIE; Fiscal Year: 2001
  8. Kinetic Studies of Transcription Elongation
    DOROTHY ERIE; Fiscal Year: 2005
  9. DNA Damage Clusters: Repair in Mammalian Cells
    Betsy Sutherland; Fiscal Year: 2004
  10. REGULATION OF BILIPROTEIN IN CYANOBACTERIA
    DONALD BRYANT; Fiscal Year: 2002

Detail Information

Publications232 found, 100 shown here

  1. ncbi Evaluation of carboprost tromethamine in the treatment of cyclophosphamide-induced hemorrhagic cystitis
    L A Levine
    Section of Urology, University of Chicago, IL 60637
    Cancer 66:242-5. 1990
    ..Each patient had failed to respond to conservative management. Carboprost tromethamine (Hemabate) was instilled into the bladder, with dwell times ranging from 45 to 60 minutes, three to four times ..
  2. ncbi Comparison of oral nonsteroidal analgesic and intrauterine local anesthetic for pain relief in uterine fractional curettage: a randomized, double-blind, placebo-controlled trial
    Olus Api
    Department of Obstetrics and Gynecology, Dr Lutfi Kirdar Kartal Teaching and Research Hospital, Acelya Sok No 12 2, Dragos Kartal, Istanbul, Turkey
    Am J Obstet Gynecol 203:28.e1-7. 2010
    ..We sought to investigate the analgesic efficacy of oral dexketoprofen trometamol and intrauterine lidocaine in patients undergoing fractional curettage...
  3. ncbi Effect of pH value of freeze-drying solution on the chromosome integrity and developmental ability of mouse spermatozoa
    Takehito Kaneko
    The Institute for Biogenesis Research, Department of Anatomy and Reproductive Biology, John A Burns School of Medicine, University of Hawaii, Honolulu, Hawaii 96822, USA
    Biol Reprod 68:136-9. 2003
    ..0) rather than near neutral or acidic (pH 7.4-6.0). The data indicated that the chromosome integrity and developmental ability of mouse spermatozoa are affected by the pH value of freeze-drying solution...
  4. ncbi Analgesic efficacy and safety of nonpreserved ketorolac tromethamine ophthalmic solution following radial keratotomy. Ketorolac Radial Keratotomy Study Group
    R W Yee
    University of Texas at Houston, 77030, USA
    Am J Ophthalmol 125:472-80. 1998
    To compare the analgesic efficacy and safety of nonpreserved ketorolac tromethamine 0.5% with those of its vehicle in the treatment of postsurgical ocular pain following radial keratotomy.
  5. ncbi Prophylactic and therapeutic carboprost tromethamine bladder irrigation in rats with cyclophosphamide-induced hemorrhagic cystitis
    D M Kranc
    Department of Surgery Urology, University of Chicago, Illinois
    J Urol 148:1326-30. 1992
    ..Among the prostaglandins studied is carboprost tromethamine, a PGF2a analog...
  6. ncbi Entry of tromethamine into the cerebrospinal fluid of humans after cerebrovascular events
    R Nau
    Department of Neurology, Georg August Universitat, Gottingen, Germany
    Clin Pharmacol Ther 66:25-32. 1999
    The intravenous administration of tromethamine (INN, trometamol) lowers the intracranial pressure in patients with brain edema. One postulated mechanism of action is the increase of the pH of the cerebrospinal fluid.
  7. ncbi The treatment of acidosis in acute lung injury with tris-hydroxymethyl aminomethane (THAM)
    R H Kallet
    Department of Anesthesia and Division of Pulmonary and Critical Care Medicine, University of California, San Francisco at San Francisco General Hospital, San Francisco, California 94110, USA
    Am J Respir Crit Care Med 161:1149-53. 2000
    ..Although further studies are needed to confirm these observations, THAM appears to be an effective alternative to sodium bicarbonate for treating acidosis during ALI...
  8. ncbi The effects on platelet aggregation and prostanoid biosynthesis of two parenteral analgesics: ketorolac tromethamine and dipyrone
    G Geisslinger
    Department of Experimental and Clinical Pharmacology, University of Graz, Austria
    Thromb Haemost 76:592-7. 1996
    The pharmacokinetics and effects on platelet function of dipyrone (1.0 g; 2.5 g; i.v.) and ketorolac tromethamine (30 mg; i.m.) were studied in a three-way crossover study in twelve healthy subjects...
  9. ncbi Treating intraoperative hyperchloremic acidosis with sodium bicarbonate or tris-hydroxymethyl aminomethane: a randomized prospective study
    Markus Rehm
    Klinik fur Anaesthesiologie, Ludwig Maximilians Universitat, Klinikum Grosshadern, Marchioninistrasse 15, D 18377 Munich, Germany markus rehm ana med uni muenchen de
    Anesth Analg 96:1201-8, table of contents. 2003
    ..8 mmol/L because of the occurrence of an unmeasured cation. In conclusion, in case of buffering with BIC or THAM, the changes in pH were accompanied by, and probably caused by, an increase in strong ion difference...
  10. ncbi Investigation of novel quantum dots/proteins/cellulose bioconjugate using NSOM and fluorescence
    Peng Zhang
    Department of Chemistry, New Mexico Institute of Mining and Technology, Socorro, New Mexico 87801, USA
    J Fluoresc 16:349-53. 2006
    ..The spectroscopic change of spectroscopic properties of the QDs upon bioconjugation, indicating the interaction among the immobilized QDs and between the constructed protein and QDs...
  11. ncbi Effect of buffer species on the thermally induced aggregation of interferon-tau
    Derrick S Katayama
    Center for Pharmaceutical Biotechnology, University of Colorado Health Sciences Center, Denver, CO, USA
    J Pharm Sci 95:1212-26. 2006
    ..This study represents the first detailed biophysical study of specific buffer-induced stabilization, resulting in shifting the equilibrium towards the native state and away form the expanded aggregation-competent species...
  12. ncbi Histone-DNA binding free energy cannot be measured in dilution-driven dissociation experiments
    A Thåström
    Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, Illinois 60208 3500, USA
    Biochemistry 43:736-41. 2004
    ..Kinetic stability is of practical importance: it may govern nucleosome function in vivo, and it may (but need not) parallel absolute thermodynamic stability...
  13. ncbi Using hydrophilic adhesive tape for collection of evidence for forensic DNA analysis
    Richard C Li
    Forensic Science Program, College of Criminal Justice, Sam Houston State University, Huntsville, TX 77341 2296, USA
    J Forensic Sci 48:1318-21. 2003
    ..In addition, this collection method should reduce the risk of DNA degradation due to the moisture, which is encountered using conventional collecting methods...
  14. ncbi Increased lactate levels impair the coagulation system--a potential contributing factor to progressive hemorrhage after traumatic brain injury
    Martin Engstrom
    Department of Anaesthesia and Intensive Care, Lund University Hospital, Sweden
    J Neurosurg Anesthesiol 18:200-4. 2006
    ..It may also be important to consider in bleeding trauma patients...
  15. ncbi Biochemical characterization of the dissociated forms from the core antenna proteins from purple bacteria
    Veronique Arluison
    Section de Biophysique des Fonctions Membranaires, DBJC CEA and URA CNRS 2096, C E SACLAY, 91191 Gif sur Yvette Cedex, France
    Biochemistry 41:11812-9. 2002
    ....
  16. ncbi Peculiar features of the aggregation effect of silver(I) ion on hemoglobin
    Anatoli E Myshkin
    Institute of Biochemical Physics, Russian Academy of Sciences, 117977, V 334 Moscow, Russia
    Biochim Biophys Acta 1651:124-9. 2003
    ..Mercury ligands, in particular, Tris molecules and OH(-) anions markedly suppress the protein coagulation, thereby supporting the proposed protein aggregation mechanism...
  17. ncbi Buffer administration during CPR promotes cerebral reperfusion after return of spontaneous circulation and mitigates post-resuscitation cerebral acidosis
    Xiaoli Liu
    Uppsala University Hospital, Department of Surgical Sciences Anesthesiology and Intensive Care, SE 751 85 Uppsala, Sweden
    Resuscitation 55:45-55. 2002
    ..The arterial alkalosis often noticed during CPR after the administration of alkaline buffers was caused by low systemic blood flow, which also results in poor outcome...
  18. ncbi Nonradioactive assay for quality control of flat-bottom pins during DNA-array production
    Stefan Kotschote
    GPC Biotech AG, Munich, Germany
    Biotechniques 35:266-8, 270. 2003
  19. ncbi Langmuir and Langmuir-Blodgett films of organophosphorus acid anhydrolase
    Sarita V Mello
    Department of Chemistry, University of Miami, Coral Gables, Florida 33146, USA
    Biomacromolecules 4:968-73. 2003
    ..The clear, pronounced response and the stability of the LB film as a DFP sensor show the potential of this system as a biosensor...
  20. ncbi Differential effect of buffer on the spin trapping of nitric oxide by iron chelates
    S Porasuphatana
    Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland 21201, USA
    Anal Biochem 298:50-6. 2001
    ..7 than was Fe(DTCS)2. Data suggested that Fe(DTCS)2 and Fe(MGD)2 are efficient at spin trapping NO* but their maximal efficiency may be affected by experimental conditions...
  21. ncbi A macrocyclic polyamine as an anion receptor in the capillary electrochromatographic separation of carbohydrates
    Chuen Ying Liu
    Department of Chemistry, National Taiwan University, Taipei, Taiwan
    J Chromatogr A 1154:407-15. 2007
    ....
  22. ncbi Relationship between stability of folding intermediates and amyloid formation for the yeast prion Ure2p: a quantitative analysis of the effects of pH and buffer system
    Li Zhu
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing 100101, People s Republic of China
    J Mol Biol 328:235-54. 2003
    ..In Tris buffer the lag time is increased, suggesting that stabilization of the native state disfavours amyloid nucleation...
  23. ncbi SDS disc electrophoresis of proteins in homogeneous, low-concentrated polyacrylamide gels
    I Piotr Maly
    Section of Functional Neuroanatomy, Institute of Anatomy, DKBW, University of Basel, Basel, Switzerland
    Electrophoresis 28:1508-13. 2007
    ..The gel system is easy to prepare and, due to the very low acrylamide concentrations, it is ideal for analytical as well as for preparative tasks...
  24. ncbi Calorimetric determination of thermodynamic parameters of reaction reveals different enthalpic compensations of the yeast hexokinase isozymes
    M Lucia Bianconi
    Departamento de Bioquimica Medica, Intituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941 590, Brazil
    J Biol Chem 278:18709-13. 2003
    ..The differences in Delta HR obtained here for both isozymes strongly suggest that, besides glucose phosphorylation, another side reaction such as ATP hydrolysis and/or enzyme phosphorylation is taking place...
  25. ncbi Effects of common buffer systems on drug activity: the case of clerocidin
    Sara Richter
    Department of Pharmaceutical Sciences, University of Padova, Via Marzolo 5, 35131 Padova, Italy
    Chem Res Toxicol 17:492-501. 2004
    ....
  26. ncbi Hemifluorinated surfactants: a non-dissociating environment for handling membrane proteins in aqueous solutions?
    Cécile Breyton
    Laboratoire de Physicochimie Moléculaire des Membranes Biologiques, UMR 7099, CNRS and Universite Paris 7, Institut de Biologie Physico Chimique, 13 rue Pierre et Marie Curie, F 75005 Paris, France
    FEBS Lett 564:312-8. 2004
    ..The stabilization of cytochrome b(6)f is at least partly due to a better retention of protein-bound lipids...
  27. ncbi Models of protein modification in Tris-glycine and neutral pH Bis-Tris gels during electrophoresis: effect of gel pH
    John P Hachmann
    Invitrogen Corporation, Carlsbad, CA 92008, USA
    Anal Biochem 342:237-45. 2005
    ..5 versus the conventional pH 6.8 of Tris-glycine gels. It is shown that significantly less protein degradation occurs during sample preparation at the higher pH used with Bis-Tris gels...
  28. ncbi Long-term motility and fertility conservation of chilled canine semen using egg yolk added Tris-glucose extender: in vitro and in vivo studies
    J P Verstegen
    College of Veterinary Medicine, LACS Small Animal Reproduction, University of Florida Gainesville, P O B 10036, 2015 SW 16 AV, Gainesville, USA
    Theriogenology 64:720-33. 2005
    ..The role of energetic substrate and pH alteration is postulated and the classically accepted relation of semen motility/viability is raised...
  29. ncbi Cu(II) complexation by "non-coordinating" N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid (HEPES buffer)
    Magdalena Sokołowska
    Faculty of Chemistry, University of Wrocław, F Joliot Curie 14, 50 383 Wrocław, Poland
    J Inorg Biochem 99:1653-60. 2005
    ..Therefore, HEPES can still be recommended for Cu(II) studies in place of other common buffers, such as Tris and phosphate, but appropriate corrections and precautions should be applied in quantitative experiments...
  30. ncbi Effectiveness of a tris-based extender (SHOTOR diluent) for the preservation of Bactrian camel (Camelus bactrianus) semen
    A Niasari-Naslaji
    Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
    Cryobiology 53:12-21. 2006
    ..05). In conclusion, the utilization of a tris-based extender, having the osmolality of 330 mOsm/kg and pH of 6.9, favors the short-term preservation of the Bactrian camel spermatozoa under chilled condition...
  31. ncbi Chiral ion-exchange capillary electrochromatography of arylglycine amides with dextran sulfate as a pseudostationary phase
    Yi Chen
    Laboratory of Analytical Chemistry for Life Science, Department of Chemical Biology, Institute of Chemistry, Chinese Academy of Science, Beijing, P R China
    Electrophoresis 26:833-40. 2005
    ..The amido group was shown irreplaceable to have chiral resolution with DS alone as an ionic and chiral pseudostationary phase...
  32. ncbi Small diamines as modifiers for phosphatidylcholine/phosphatidylserine coatings in capillary electrochromatography
    Sami J O Varjo
    Laboratory of Analytical Chemistry, Department of Chemistry, PO Box 55, FIN 00014 University of Helsinki, Finland
    J Chromatogr A 1081:92-8. 2005
    ..The factors affecting phospholipid coatings with diamines as modifiers are clarified...
  33. pmc Tris-borate is a poor counterion for RNA: a cautionary tale for RNA folding studies
    Karen L Buchmueller
    Department of Chemistry, University of North Carolina, Chapel Hill, NC 27599 3290, USA
    Nucleic Acids Res 32:e184. 2004
    ..Under some conditions, Tris-borate is a poor counterion for RNA and its use merits careful evaluation in RNA folding studies...
  34. ncbi Effect of glass dissolution products on the detection of proteins by silver staining
    M M Hall
    Alfred University, School of Engineering, Binns Merrill Hall, 2 Pine Street, Alfred, New York 14802, USA
    J Biomed Mater Res B Appl Biomater 75:435-41. 2005
    ..The cause of this behavior may be due to an interference with the fixation stage of the staining protocol, thereby resulting in the loss of protein in subsequent rinsing stages...
  35. ncbi Preliminary studies on cryopreservation of hare (Lepus europaeus Pallas, 1778) semen
    Roland Kozdrowski
    Department and Clinic of Reproduction, Ruminants Diseases and Animal Health Protection, Agricultural University of Wrocław, Plac Grunwaldzki 49, 50 366 Wrocław, Poland
    Anim Reprod Sci 93:379-82. 2006
    ..10+/-3.69% and percentage of live spermatozoa 35.05+/-4.21%. Based on the properties of freezing-thawing semen, the hare semen can be successfully preserved in extender used for rabbit semen...
  36. ncbi Primary structure elements of spider dragline silks and their contribution to protein solubility
    Daniel Huemmerich
    Department of Biotechnology, Technische Universitat Munchen, Lichtenbergstrasse 4, 85747 Garching, Germany
    Biochemistry 43:13604-12. 2004
    ....
  37. ncbi Influence of glucose and fructose in the extender during long-term storage of chilled canine semen
    Suppawiwat Ponglowhapan
    Department of Obstetrics and Gynaecology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences SLU, PO Box 7039, SE 750 07 Uppsala, Sweden
    Theriogenology 62:1498-517. 2004
    ..EYT extender supplemented with fructose at a concentration of 70 mM was found to be the best of the tested extenders for long-term preservation of chilled canine semen...
  38. ncbi History and principles of conductive media for standard DNA electrophoresis
    Jonathan R Brody
    Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Anal Biochem 333:1-13. 2004
    ..Such media allow for application of a higher electric field. Applications of DNA electrophoresis can now be reengineered for lower ionic strength, higher field strengths, and lower requirements for heat dissipation...
  39. ncbi Effects of egg yolk during the freezing step of cryopreservation on the viability of goat spermatozoa
    Eiman M E Aboagla
    Laboratory of Animal Reproduction, Graduate School of Biosphere Sciences, Hiroshima University, Higashi Hiroshima, Hiroshima 739 8528, Japan
    Theriogenology 62:1160-72. 2004
    ..Furthermore, although neither glycerol nor egg yolk per se affected the proportion of intact acrosomes, the combination of the two significantly reduced the proportion of acrosome-intact spermatozoa...
  40. ncbi Improvements in two-dimensional gel electrophoresis by utilizing a low cost "in-house" neutral pH sodium dodecyl sulfate-polyacrylamide gel electrophoresis system
    David R M Graham
    Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Proteomics 5:2309-14. 2005
    ..Their utility is demonstrated using albumin-depleted serum samples, rabbit heart left ventricle, and human immunodeficiency virus type 1 (HIV-1)...
  41. ncbi Ability to activate oocytes and chromosome integrity of mouse spermatozoa preserved in EGTA Tris-HCl buffered solution supplemented with antioxidants
    Hirokazu Kusakabe
    Department of Biological Sciences, Asahikawa Medical College, 2 1 1 1 Midorigaoka Higashi, 078 8510, Japan
    Theriogenology 62:897-905. 2004
    ..These results suggested that deterioration of spermatozoa preserved in ETBS alone was delayed by supplementation with antioxidants...
  42. ncbi Factors determining types and morphologies of calcium oxalate crystals: molar concentrations, buffering, pH, stirring and temperature
    Visith Thongboonkerd
    Medical Molecular Biology Unit, Office for Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, 12th Floor Adulyadej Vikrom Building, 2 Prannok Road, Bangkoknoi, Bangkok 10700, Thailand
    Clin Chim Acta 367:120-31. 2006
    ..Calcium oxalate (CaOx) can be crystallized in several forms and morphologies. We evaluated factors that determine differential types and shapes of CaOx crystals generated in vitro...
  43. ncbi Influence of extender, freezing rate, and thawing rate on post-thaw motility, viability and morphology of coyote (Canis latrans) spermatozoa
    Larry J Minter
    Utah State University, Department of Fisheries and Wildlife, Logan, UT 84322, USA
    Theriogenology 64:1898-912. 2005
    ..5-44.0%) and viability (range, 64-49.6%) with the least amount of morphological and acrosomal abnormalities...
  44. ncbi Simultaneous determination of cefepime and vancomycin in plasma and cerebrospinal fluid by MEKC with direct sample injection and application for bacterial meningitis
    Yuan Han Yang
    Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Electrophoresis 28:1788-97. 2007
    ..5 microg/mL, respectively. The applicability of the proposed method for the determination of cefepime and vancomycin in plasma and CSF collected after intravenous administration of the drugs in patients with meningitis was demonstrated...
  45. ncbi HCO3- potentiates the cAMP-dependent secretory response of the human distal colon through a DIDS-sensitive pathway
    J Taylor
    Department of Physiology, School of Medical Sciences, University of Otago, P.O. Box 913, Dunedin, New Zealand
    Pflugers Arch 442:256-62. 2001
    ....
  46. ncbi Mathematical modeling of buffers used in myocardial preservation
    Jonathan R Triana
    Sarver Heart Center, College of Medicine, The University of Arizona, Tucson, AZ 85724, USA
    Perfusion 22:353-62. 2007
    ..Our hypothesis is that mathematical modeling of three clinically used buffers will define their individual buffering capacities under simulated clinical conditions...
  47. ncbi Evaluation of possible reasons for the low phenylalanine ammonia lyase activity in cellulose nitrate membrane microcapsules
    S Habibi-Moini
    Department of Pharmaceutical Sciences, University of the Sciences in Philadelphia, PA 19104, USA
    Int J Pharm 215:185-96. 2001
    ..However, encapsulated PAL had a 50% lower V(max) value compared to free PAL, which showed that the microencapsulation process deactivated a substantial proportion of the enzyme...
  48. ncbi Polymorphic assemblies and crystalline arrays of lens tetraspanin MP20
    Tamir Gonen
    School of Biological Sciences, University of Auckland, Auckland, New Zealand
    J Mol Biol 376:380-92. 2008
    ..The various complexes formed by MP20 most likely reflect the many ways in which tetraspanins can interact with each other to allow formation of TEMs...
  49. ncbi Effect of buffer components and carrier solvents on in vitro activity of recombinant human carboxylesterases
    Eric T Williams
    Department of Drug Disposition, Lilly Research, Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States
    J Pharmacol Toxicol Methods 57:138-44. 2008
    ..Therefore, it is unknown if the many different assay conditions used by various laboratories have a substantial impact on the activity of CE enzymes...
  50. ncbi Analysis of vancomycin and related impurities by micellar electrokinetic capillary chromatography. Method development and validation
    J W Kang
    Laboratorium voor Farmaceutische Chemie en Analyse van Geneesmiddelen, Faculteit Farmaceutische Wetenschappen, Katholieke Universiteit Leuven, Belgium
    Electrophoresis 22:2588-92. 2001
    ..The limit of detection (LOD) and limit of quantitation (LOQ) were 0.4 microg/mL vancomycin, equivalent to 0.3 microg/mL vancomycin B (0.04%) and 1.1 microg/mL vancomycin, equivalent to 0.9 microg/mL vancomycin B (0.1%), respectively...
  51. ncbi Internal pH indicators for biomolecular NMR
    Olga K Baryshnikova
    Department of Biochemistry, University of Alberta, Edmonton, AB, Canada T6G 2H7
    J Biomol NMR 41:5-7. 2008
    ..5 to 9.8. This method is suitable for a wide range of applications where samples are handled intensively during NMR titrations or in high throughput analysis in structural genomics or metabolomics...
  52. ncbi New buffers to improve the quantitative real-time polymerase chain reaction
    Ashraf Ahmad
    Department of Chemical and Biological Engineering Molecular Biotechnology, Chalmers University of Technology, Goteborg, Sweden
    Biosci Biotechnol Biochem 71:1970-8. 2007
    ..Mixing more than one compound with the Tris buffer was also effective for expanding the dynamic range and increasing the efficiency and correlation coefficient in quantitative real-time PCR...
  53. ncbi A novel [Ag(NH3)2]+ probe for chemiluminescent imaging detection of proteins after polyacrylamide gel electrophoresis
    Xin Xiong
    College of Chemistry, Beijing Normal University, Beijing, PR China
    Proteomics 7:2511-21. 2007
    ..The CL imaging conditions, including luminescent reagents, silver ion concentration, the ammonia-controlled system and the washing reagents parameters have also been optimized...
  54. ncbi Autonomous microfluidic multi-channel chip for real-time PCR with integrated liquid handling
    Olivier Frey
    Sensors, Actuators and Microsystems Laboratory, Institute of Microtechnology, University of Neuchatel, rue Jaquet Droz 1, 2000, Neuchatel, Switzerland
    Biomed Microdevices 9:711-8. 2007
    ..Successful real-time PCR and the determination of the threshold cycle, Ct, using the developed device were demonstrated with plasmid DNA in a fluorescent real-time format...
  55. ncbi Acidosis and impaired blood coagulation: what and how to correct before using recombinant human factor VIIa
    Carl Erik Dempfle
    Crit Care Med 35:1627-9. 2007
  56. ncbi Analysis of organic acids and inorganic anions in beverage drinks by capillary electrophoresis
    Ying Sing Fung
    Department of Chemistry, The University of Hong Kong, Hong Kong SAR, China
    Electrophoresis 24:3224-32. 2003
    ..Our CZE procedure provided a sensitive and economic technique for simultaneous determination of inorganic and organic acid anions in orange juice, red and white wine samples...
  57. ncbi An alternate high yielding purification method for Clitoria ternatea lectin
    Aabgeena Naeem
    Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh 202002, India Department of Biochemistry, Life Science, AMU, Aligarh 202002, India
    Int J Biol Macromol 41:481-6. 2007
    ..The content of lectin was found to be 30mg/30g dry weight of pulse. The yield was 2.8% as compared to 0.3% obtained on fetuin column. The number of tryptophan and tyrosine estimated was four and six per subunit...
  58. ncbi Two pathways of iron uptake in bovine spleen apoferritin dependent on iron concentration
    Koichi Orino
    Laboratory of Biochemistry, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan
    Biometals 15:59-63. 2002
    ..These results demonstrate that iron loading of apoferritin was accomplished at physiological iron concentrations, which is essential for iron uptake, via two uptake pathways of dependent on iron concentration...
  59. ncbi Multidrug-resistant Gram-negative infections: what are the treatment options?
    Helen Giamarellou
    4th Department of Internal Medicine, Athens University School of Medicine, ATTIKON University Hospital of Athens, Athens, Greece
    Drugs 69:1879-901. 2009
    ..Fosfomycin tromethamine, a synthetic salt of fosfomycin discovered in 1969, has regained attention because of its in vitro activity ..
  60. ncbi Gateways to Clinical Trials. June 2002
    M Bayes
    Methods Find Exp Clin Pharmacol 24:291-327. 2002
    ..beta, interferon beta-1a, interferon beta-1b, interferon omega, irbesartan, itraconazole; Ketorolac, ketorolac tromethamine; Lamifiban, lamotrigine, lanoteplase, lansoprazole, leflunomide, leuprorelin acetate, levetiracetam, ..
  61. ncbi Effects of cloprostenol sodium at final prostaglandin F2α of Ovsynch on complete luteolysis and pregnancy per artificial insemination in lactating dairy cows
    J P N Martins
    Department of Animal Science, Michigan State University, East Lansing 48824, USA
    J Dairy Sci 94:2815-24. 2011
    ..as 20% of cows treated with a Presynch/Ovsynch program have delayed or incomplete luteolysis using dinoprost tromethamine. Cows must have complete luteolysis to have a chance to become pregnant...
  62. ncbi Ketorolac versus prednisolone versus combination therapy in the treatment of acute pseudophakic cystoid macular edema
    J S Heier
    Ophthalmic Consultants of Boston, Boston, Massachusetts, USA
    Ophthalmology 107:2034-8;discussion 2039. 2000
    To evaluate the efficacy of ketorolac tromethamine 0.5% ophthalmic solution, prednisolone acetate 1...
  63. ncbi The effect of estrus synchronization treatment on somatic cell count of transitional-anestrus local-Damascus cross breed goats' milk
    A Q Talafha
    Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, P O Box 3030, Irbid 22110, Jordan
    Trop Anim Health Prod 40:185-92. 2008
    ..In addition, goats of FGA-PGF group were injected with 10 mg dinoprost tromethamine (PGF2alpha) on day 0. Five fertile local-Damascus cross bucks were turned-in with all goats on day 0...
  64. ncbi Sublingual hyoscyamine sulfate in combination with ketorolac tromethamine for ureteral colic: a randomized, double-blind, controlled trial
    J B Jones
    Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    Ann Emerg Med 37:141-6. 2001
    We evaluate the safety and efficacy of a single dose of hyoscyamine sulfate in combination with ketorolac tromethamine for the reduction of pain in emergency department patients with ureteral colic.
  65. ncbi Treatment of acute pseudophakic cystoid macular edema: Diclofenac versus ketorolac
    David S Rho
    Department of Ophthalmology, Manhattan Eye, Ear and Throat Hospital, New York, NY, USA
    J Cataract Refract Surg 29:2378-84. 2003
    ..1% solution (Voltaren Ophthalmic) is as efficacious as topical ketorolac tromethamine 0...
  66. ncbi Retinal toxicity of commercially available intravitreal ketorolac in albino rabbits
    Izabela Komarowska
    Department of Physiology and Biophysics, Ruth and Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology and the Rappaport Institute, Haifa, Israel
    Retina 29:98-105. 2009
    To determine whether intravitreal injection of a commercially available ketorolac tromethamine preparation causes retinal toxicity in albino rabbits.
  67. ncbi Release studies on niosomes containing fatty alcohols as bilayer stabilizers instead of cholesterol
    Gopi N Devaraj
    University College of Pharmaceutical Sciences, Kakatiya University, Warangal, 506 009, India
    J Colloid Interface Sci 251:360-5. 2002
    ..Aqueous solution of ketorolac tromethamine (KT) was entrapped in them...
  68. ncbi Preoperative ketorolac tromethamine 0.4% in phacoemulsification outcomes: pharmacokinetic-response curve
    Eric D Donnenfeld
    J Cataract Refract Surg 32:1474-82. 2006
    To assess the clinical benefit, relative efficacy, and pharmacokinetic-response curve of preoperative and postoperative ketorolac tromethamine 0.4% (Acular LS) to improve outcomes during and after cataract surgery.
  69. pmc Treatment of retinopathy of prematurity with topical ketorolac tromethamine: a preliminary study
    Medardo Avila-Vazquez
    NICU, Neonatalogy Service, Hospital Universitario de Maternidad y Neonatologia, Universidad Nacional de Cordoba, Cordoba, Argentina
    BMC Pediatr 4:15. 2004
    ..This is a preliminary report of the effectiveness and safety of a new and original use of topical ketorolac in preterm newborn to prevent the progression of ROP to the more severe forms of this disease...
  70. ncbi Inhibition of choroidal neovascularization by intravitreal ketorolac
    Stephen J Kim
    Department of Ophthalmology and Visual Sciences, Vanderbilt University, Nashville, Tennessee, USA
    Arch Ophthalmol 128:596-600. 2010
    ..To determine the inhibitory effect of intravitreal nonsteroidal anti-inflammatory drugs on choroidal neovascularization (CNV) in an animal model of age-related macular degeneration...
  71. ncbi Evaluation of 0.4% ketorolac tromethamine ophthalmic solution versus 0.5% ketorolac tromethamine ophthalmic solution after phacoemulsification and intraocular lens implantation
    Helga P Sandoval
    Magill Research Center for Vision Correction, Medical University of South Carolina, Storm Eye Institute, Charleston, SC 29425, USA
    J Ocul Pharmacol Ther 22:251-7. 2006
    The aim of this study was to compare the effectiveness and patient tolerance of 0.4% ketorolac tromethamine ophthalmic solution and 0.5% ketorolac tromethamine ophthalmic solution after routine phacoemulsification and lens implantation.
  72. ncbi Fosfomycin tromethamine as second agent for the treatment of acute, uncomplicated urinary tract infections in adult female patients in The Netherlands?
    B J Knottnerus
    Department of General Practice, Academic Medical Centre, Amsterdam, The Netherlands
    J Antimicrob Chemother 62:356-9. 2008
    ..The third choice is fosfomycin tromethamine for which no current resistance data from The Netherlands are available...
  73. ncbi Comparison of prednisolone 1%, rimexolone 1% and ketorolac tromethamine 0.5% after cataract extraction: a prospective, randomized, double-masked study
    Christoph Hirneiss
    Department of Ophthalmology, Ludwig Maximilians University, Mathildenstrasse 8, 80336 Munich, Germany
    Graefes Arch Clin Exp Ophthalmol 243:768-73. 2005
    To compare the efficacy, safety and patient comfort of two topical steroids (prednisolone 1% and rimexolone 1%) and a topical non-steroidal anti-inflammatory agent (ketorolac tromethamine 0.5%) after extracapsular cataract extraction.
  74. ncbi Comparative study of 0.1% olopatadine hydrochloride and 0.5% ketorolac tromethamine in the treatment of seasonal allergic conjunctivitis
    Volkan Yaylali
    Department of Ophthalmology, Pamukkale University School of Medicine, 20010 Denizli, Turkey
    Acta Ophthalmol Scand 81:378-82. 2003
    ..To compare the therapeutic effects of two ophthalmic solutions (0.1% olopatadine hydrochloride and 0.5% ketorolac tromethamine) with different pharmacological mechanisms on the clinical signs and Symptoms of seasonal allergic ..
  75. ncbi JSAR Innovative Technology Award. Development of ovulation synchronization and fixed time artificial insemination in dairy cows
    Kyoji Yamada
    Shibetsu Veterinary Clinical Center, Nemuro District NOSAI, Hokkaido, Japan
    J Reprod Dev 51:177-86. 2005
    ..A steady and sufficient conception rate after Ovsynch/TAI could be expected by taking the factors affecting the conception rate into the consideration...
  76. ncbi Comparison of ketorolac tromethamine 0.5% and rimexolone 1% to control inflammation after cataract extraction. Prospective randomized double-masked study
    K D Solomon
    Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston, 29425, USA
    J Cataract Refract Surg 27:1232-7. 2001
    To compare the efficacy of a topical nonsteroidal anti-inflammatory agent (ketorolac tromethamine 0.5%) with that of a topical steroid (rimexolone 1%) to control inflammation after cataract surgery.
  77. ncbi Comparison of ketorolac tromethamine, diclofenac sodium, and loteprednol etabonate in an animal model of ocular inflammation
    L David Waterbury
    J Ocul Pharmacol Ther 22:155-9. 2006
    The aim of this study was to compare the anti-inflammatory activities of ketorolac tromethamine 0.4% and 0.1%; diclofenac sodium 0.1%; and loteprednol etabonate 0.5% suspension in an animal model of ocular inflammation.
  78. ncbi Ketorolac plus tobramycin/dexamethasone versus tobramycin/dexamethasone after uneventful phacoemulsification surgery: a randomized controlled trial
    Irini P Chatziralli
    Department of Ophthalmology, Veroia General Hospital, 28 Papanastasiou Street, Veroia, Greece
    Ophthalmologica 225:89-94. 2011
    ....
  79. ncbi Postoperative ketorolac tromethamine use in infants aged 6-18 months: the effect on morphine usage, safety assessment, and stereo-specific pharmacokinetics
    Anne M Lynn
    Department of Anesthesia and Pain Management, Children s Hospital and Regional Medical Center, University of Washington School of Medicine, Seattle, Washington 98105, USA
    Anesth Analg 104:1040-51, tables of contents. 2007
    ..The only parenteral nonsteroidal antiinflammatory drug currently available in the United States is ketorolac tromethamine with cyclooxygenase-1 and cyclooxygenase-2 effects...
  80. ncbi Formulation, characterization, and evaluation of ketorolac tromethamine-loaded biodegradable microspheres
    Vivek Ranjan Sinha
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
    Drug Deliv 12:133-9. 2005
    Ketorolac tromethamine has to be given every 6 hr intramuscularly in patients for acute pain, so to avoid frequent dosing and patient inconvenience we found it to be a suitable candidate for parenteral controlled delivery by biodegradable ..
  81. ncbi Use of Acular LS in the pain management of keratoconus: a pilot study
    Jessica O Yu
    Clinical Sciences, Contact Lens Research Group, SUNY State College of Optometry, New York, New York, USA
    Optom Vis Sci 87:125-30. 2010
    The purpose of this pilot study was to determine the efficacy of ketorolac tromethamine 0.4% for pain management in conjunction with rigid gas permeable contact lenses in keratoconus...
  82. pmc Entrapment of ketorolac tromethamine in polymeric vehicle for controlled drug delivery
    S K Paliwal
    Department of Pharmaceutical Science, Faculty of Life Sciences, Banasthali Vidyapith 304 022, India
    Indian J Pharm Sci 71:687-91. 2009
    ..type E/RL/RS, Carbopol ETD 2020 and Carbopol 934 National Formulary were formulated with drug, ketorolac tromethamine. The adhesive strength of polymers on corneal surface and permeation characteristics of drug through cornea ..
  83. ncbi Effects of the 2-amino-3-hydroxy-5-methyl-4-isoxazole-proprionic acid/kainate antagonist LY293558 on spontaneous and evoked postoperative pain
    I Gilron
    Pain and Neurosensory Mechanisms Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892 1258, USA
    Clin Pharmacol Ther 68:320-7. 2000
    ..Previous studies suggest that 2-amino-3-hydroxy-5-methyl-4-isoxazole-proprionic acid (AMPA)/kainate antagonists reduce experimentally induced pain. There have been no studies of AMPA/kainate antagonists in clinical pain...
  84. ncbi Comparison of cyclooxygenase inhibitory activity and ocular anti-inflammatory effects of ketorolac tromethamine and bromfenac sodium
    L David Waterbury
    Pacific BioLabs, Hercules, CA 94070, USA
    Curr Med Res Opin 22:1133-40. 2006
    To compare the cyclooxygenase (COX) activity and anti-inflammatory effects of the nonsteroidal anti-inflammatory drugs (NSAIDs) ketorolac tromethamine (ketorolac) and bromfenac sodium (bromfenac).
  85. ncbi Ovulatory response and embryo yield in Jakhrana goats following treatments with PMSG and FSH
    A K Goel
    Embryo Transfer Technology Laboratory, Physiology, Reproduction and Shelter Management Division, Central Institute for Research on Goats, Makhdoom, PO Farah 281122, Mathura, UP India
    Trop Anim Health Prod 37:549-58. 2005
    ..To synchronize oestrus, a luteolytic dose of carboprost tromethamine (Upjohn, UK) was administered intramuscularly to all does at the dose rate of 5 microg per kg body weight in a ..
  86. ncbi Initial salt screening procedures for manufacturing ibuprofen
    Tu Lee
    Department of Chemical and Materials Engineering, National Central University, Jhong Li City, Taiwan, Republic of China
    Drug Dev Ind Pharm 35:555-67. 2009
    ..The future work is to search for the different polymorphs of this amine salt of ibuprofen and to extend the initial salt screening working logics to the formation of co-crystals...
  87. ncbi Analysis of the analgesic interactions between ketorolac and tramadol during arthritic nociception in rat
    Francisco Javier López-Muñoz
    Laboratorio No 7, Dolor y Analgesia del Departamento de Farmacobiología, CINVESTAV IPN, Calzada de los Tenorios No 235, Col Granjas Coapa, Deleg Tlalpan, Mexico, DF, CP 14330 Mexico
    Eur J Pharmacol 484:157-65. 2004
    ..order to assess a possible synergistic antinociceptive interactions, the antinociceptive effects of ketorolac tromethamine, p.o., a nonsteroidal anti-inflammatory drug (NSAID), and tramadol hydrochloride, p.o...
  88. ncbi Ketorolac tromethamine LS 0.4% versus nepafenac 0.1% in patients having cataract surgery. Prospective randomized double-masked clinical trial
    Hon Vu Q Duong
    Nevada State College, Henderson, Nevada 89012, USA
    J Cataract Refract Surg 33:1925-9. 2007
    To compare the clinical, subjective, and objective outcomes of the use of 2 topical nonsteroidal antiinflammatory drugs--ketorolac tromethamine LS 0.4% (Acular) and nepafenac 0.1% (Nevanac)--in patients having cataract surgery.
  89. ncbi Efficacy and tolerability of preservative-free and preserved diclofenac and preserved ketorolac eyedrops after cataract surgery
    Saskia M Maca
    Department of Ophthalmology and Optometry, Medical University Vienna, Vienna, Austria
    Am J Ophthalmol 149:777-84. 2010
    ..To compare the anti-inflammatory efficacy and subjective tolerability of preservative-free and preserved diclofenac 0.1% and preserved ketorolac 0.5% eye drops for prophylaxis and management of inflammation after cataract surgery...
  90. ncbi Pain reduction after laser in situ keratomileusis with ketorolac tromethamine ophthalmic solution 0.5%: a randomized, double-masked, placebo-controlled trial
    Francis W Price
    Price Vision Group, Indianapolis, IN, USA
    J Refract Surg 18:140-4. 2002
    To evaluate the analgesic efficacy of ketorolac tromethamine ophthalmic solution 0.5% after laser in situ keratomileusis (LASIK).
  91. ncbi Glucocorticoids regulate intestinal glutamine synthetase gene expression in endotoxemia
    P Sarantos
    Department of Surgery, University of Florida College of Medicine, Gainesville
    Arch Surg 129:59-65. 1994
    ....
  92. ncbi Preparation and evaluation of ketorolac tromethamine gel containing genipin for periodontal diseases
    Jeon Heon Yang
    College of Pharmacy, Woosuk University, Wanju 565 701, Korea
    Arch Pharm Res 30:871-5. 2007
    Ketorolac tromethamine gel (KT gel) and ketorolac tromethamine gel containing genipin (KTG gel) were prepared and their therapeutic effects on periodontitis were evaluated...
  93. ncbi Intramuscular ketorolac versus osteopathic manipulative treatment in the management of acute neck pain in the emergency department: a randomized clinical trial
    Tamara M McReynolds
    Department of Emergency Medicine, Darnall Army Community Hospital, Fort Hood, TX, USA
    J Am Osteopath Assoc 105:57-68. 2005
    Ketorolac tromethamine injected intramuscularly (IM) has been shown to be an effective analgesic in treating patients with acute musculoskeletal pain in the emergency department (ED)...
  94. ncbi A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients
    John R Wittpenn
    State University of New York at Stony Brook, Stony Brook, New York 11790, USA
    Am J Ophthalmol 146:554-560. 2008
    To evaluate whether adding perioperative topical ketorolac tromethamine 0.4% improves cataract surgery outcomes relative to topical steroids alone in patients without known risk factors for cystoid macular edema (CME).
  95. ncbi Effects of prostaglandins and prostaglandin synthesis inhibitors on sexual behavior in boars
    Mark J Estienne
    Virginia Tech Tidewater Agricultural Research and Extension Center, 6321 Holland Road, Suffolk, VA 23437, USA
    Reprod Biol 7:163-75. 2007
    ..On each of five consecutive days, boars received i.m. treatment with saline, dinoprost tromethamine or cloprostenol sodium (n=12/group). On each of day 1 (p=0.06), day 2 (p<0.05), and day 3 (p<0...
  96. ncbi Effect of prophylactic nonsteroidal antiinflammatory drugs on cystoid macular edema assessed using optical coherence tomography quantification of total macular volume after cataract surgery
    David R P Almeida
    Department of Ophthalmology, Queen s University, Hotel Dieu Hospital, Kingston, Ontario, Canada
    J Cataract Refract Surg 34:64-9. 2008
    ..the efficacy of prophylactic administration of the topical nonsteroidal antiinflammatory drug (NSAID) ketorolac tromethamine 0...
  97. ncbi Influence of estrus on somatic cell count in dairy goats
    S McDougall
    Animal Health Centre, Morrinsville, New Zealand
    J Dairy Sci 85:378-83. 2002
    ..progesterone-releasing device was inserted for 12 d plus equine chorionic gonadotropin and dinoprost tromethamine 2 d before device removal (n = 12), b) "Long," in which an intravaginal progesterone-releasing was inserted for ..
  98. ncbi Intravenous ketorolac in the emergency department management of sickle cell pain and predictors of its effectiveness
    J L Beiter
    Department of Pediatrics, Hughes Spalding Children s Hospital, Emory University School of Medicine, Children s Healthcare of Atlanta at Egleston, GA, USA
    Arch Pediatr Adolesc Med 155:496-500. 2001
    To evaluate the effectiveness of intravenous (IV) ketorolac tromethamine in the treatment of children with sickle cell disease with moderate to severe acute vaso-occlusive pain (VOP) and to develop a predictive model that would determine ..
  99. ncbi Aldosterone secretion during acute metabolic and respiratory alkalosis in the goat
    O Augustinsson
    Department of Physiology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala
    Acta Physiol Scand 137:143-9. 1989
    ..Increased K stimulation may therefore have masked a possible inhibitory influence of the alkalosis upon the aldosterone secretion...
  100. ncbi An update on the use of ophthalmic ketorolac tromethamine 0.4%
    Henry D Perry
    Ophthalmic Consultants of Long Island, 2000 North Village Avenue, Rockville Centre, New York 11570, USA
    Expert Opin Pharmacother 7:99-107. 2006
    Ketorolac tromethamine 0.4% ophthalmic solution, a recent reformulation of the original ketorolac tromethamine 0.5% solution, is indicated for the reduction of ocular pain and burning/stinging following cataract and refractive surgery...
  101. ncbi Contact lens assisted pharmacologically induced keratoshaping
    James E McDonald
    McDonald Eye Associates, 3318 North Hills Boulevard, Fayetteville, AR 72701, USA
    Eye Contact Lens 30:122-6. 2004
    ..To retrospectively evaluate the effectiveness and describe the process of reducing hyperopia with a nonsteroidal antiinflammatory agent and a soft disposable contact lens in postoperative excimer laser patients with consecutive hyperopia...

Research Grants12

  1. Structure and Dynamics of RNA
    Arthur Pardi; Fiscal Year: 2006
    ..These data will lead to a better understanding of how dynamics correlates with the function and stability of this RNA tertiary structural motif. ..
  2. Purchase of 800 MHz NMR Spectrometer
    Arthur Pardi; Fiscal Year: 2002
    ..J. Overduin - Structure-Function Studies of RNA-A. Pardi - Structural Studies of HIV-1 Assembly and Budding- W.I. Sundquist - Structural Studies of Biologically Important Molecular Recognition- D.S. Wuttke ..
  3. Structure and Dynamics of RNA and Protein-RNA Complexes
    Arthur Pardi; Fiscal Year: 2008
    ..Overall this proposal will lead to a better understanding of molecular mechanisms that RNAs use to recognize their protein partners and to switch between their functional states. ..
  4. Structure-Function Studies of Ribozyme and RNA
    Arthur Pardi; Fiscal Year: 2008
    ..Both NMR and fluorescence techniques will be used to probe the effect of Mg2+ on the structure and dynamicsof these faster cleaving hammerhead ribozymes. ..
  5. Structure Function Studies of DNA Mismatch Repair
    Dorothy A Erie; Fiscal Year: 2010
    ....
  6. Identification of Alcohol Binding Site(s) in Protein Kinase C Epsilon
    Joydip Das; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  7. BIOPHYSICAL AND SCANNING FORCE MICROSCOPY STUDIES
    DOROTHY ERIE; Fiscal Year: 2001
    ..3) How do polymorphisms affect the above properties? ..
  8. Kinetic Studies of Transcription Elongation
    DOROTHY ERIE; Fiscal Year: 2005
    ..Accordingly, we will use this information to begin to understand, at the amino acid level, the role of NTP binding and conformational transitions in the regulation of elongation. ..
  9. DNA Damage Clusters: Repair in Mammalian Cells
    Betsy Sutherland; Fiscal Year: 2004
    ..Further, knowledge of conditions affecting formation of clustered damages, and cellular paths for dealing with them could allow the design of more effective radiation therapies. ..
  10. REGULATION OF BILIPROTEIN IN CYANOBACTERIA
    DONALD BRYANT; Fiscal Year: 2002
    ..These last studies could explain bloom disappearance in natural populations and could suggest new approaches for the control of problematic or toxic cyanobacteria in water supplies. ..
  11. 2002 Gordon Research Conference on Biopolymers
    DOROTHY ERIE; Fiscal Year: 2002
    ..The program encompasses some of the most exciting research in the field of nucleic acid and protein biophysics and promises to generate lively discussions both in and outside of the sessions. ..
  12. Mechanistic studies of DNA repair and damage response
    Dorothy A Erie; Fiscal Year: 2010
    ..abstract_text> ..