pentanols

Summary

Summary: Isomeric forms and derivatives of pentanol (C5H11OH).

Top Publications

  1. ncbi Lysis of cyanobacteria with volatile organic compounds
    Keiko Ozaki
    Graduate School of Environmental and Human Science, Meijo University, Tempaku, Nagoya 468 8503, Japan
    Chemosphere 71:1531-8. 2008
  2. ncbi Engineering Bacillus subtilis for isobutanol production by heterologous Ehrlich pathway construction and the biosynthetic 2-ketoisovalerate precursor pathway overexpression
    Shanshan Li
    Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
    Appl Microbiol Biotechnol 91:577-89. 2011
  3. pmc Eosinophil as a cellular target of the ocular anti-allergic action of mapracorat, a novel selective glucocorticoid receptor agonist
    Monica Baiula
    Department of Pharmacology, University of Bologna, Bologna, Italy
    Mol Vis 17:3208-23. 2011
  4. ncbi In vivo ocular efficacy profile of mapracorat, a novel selective glucocorticoid receptor agonist, in rabbit models of ocular disease
    Afshin Shafiee
    Department of Preclinical Pharmacology, Pharmaceutical R and D, Bausch and Lomb, Inc, Rochester, New York, USA
    Invest Ophthalmol Vis Sci 52:1422-30. 2011
  5. ncbi Olfaction and odor discrimination are mediated by the C. elegans guanylyl cyclase ODR-1
    N D L'Etoile
    Howard Hughes Medical Institute, Department of Anatomy, University of California, San Francisco 94143, USA
    Neuron 25:575-86. 2000
  6. ncbi A 13C nuclear magnetic resonance investigation of the metabolism of leucine to isoamyl alcohol in Saccharomyces cerevisiae
    J R Dickinson
    School of Pure and Applied Biology, University of Wales, Cardiff CF1 3TL, United Kingdom
    J Biol Chem 272:26871-8. 1997
  7. ncbi Applicability of CoA/acetyl-CoA manipulation system to enhance isoamyl acetate production in Escherichia coli
    Ravishankar V Vadali
    Department of Bioengineering, Rice University, 6100 Main Street MS 142, Houston, TX 77005, USA
    Metab Eng 6:294-9. 2004
  8. ncbi Reduced myocilin expression in cultured monkey trabecular meshwork cells induced by a selective glucocorticoid receptor agonist: comparison with steroids
    Bruce A Pfeffer
    Preclinical Pharmacology Department, Pharmaceutical Research and Development, Bausch and Lomb, Inc, Rochester, New York 14609, USA
    Invest Ophthalmol Vis Sci 51:437-46. 2010
  9. ncbi Bat2p is essential in Saccharomyces cerevisiae for fusel alcohol production on the non-fermentable carbon source ethanol
    Sung A Schoondermark-Stolk
    Department of Molecular Cell Biology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    FEMS Yeast Res 5:757-66. 2005
  10. pmc Mapracorat, a novel selective glucocorticoid receptor agonist, inhibits hyperosmolar-induced cytokine release and MAPK pathways in human corneal epithelial cells
    Megan E Cavet
    Pharmaceutical R and D, Bausch and Lomb, Inc, Rochester, NY 14609, USA
    Mol Vis 16:1791-800. 2010

Research Grants

  1. Alcohol and Acetaminophen Hepatotoxicity
    Jacqueline Sinclair; Fiscal Year: 2006
  2. STUDIES OF ADULT BRAIN NEUROPOIESIS
    Dennis Steindler; Fiscal Year: 2006
  3. Altering Fate of Hematopoietic and Neural Stem Cells
    Dennis Steindler; Fiscal Year: 2006
  4. REDUCED DRUG INTERACTIONS OF AZOLE ANTIFUNGAL DRUGS
    Joseph Gal; Fiscal Year: 2003
  5. Psychoneuroimmunology and Mind-Body Medicine
    Janice Kiecolt Glaser; Fiscal Year: 2005
  6. Psychoneuroimmunology and Mind-Body Interventions
    Janice Kiecolt Glaser; Fiscal Year: 2006
  7. Metabolic Engineering to Overcome N-Glycosylation Deficiency in Mammalian Cells
    Michael Betenbaugh; Fiscal Year: 2008
  8. Gating Mechanisms of CLC Chloride Channels
    Tsung Yu Chen; Fiscal Year: 2008

Detail Information

Publications178 found, 100 shown here

  1. ncbi Lysis of cyanobacteria with volatile organic compounds
    Keiko Ozaki
    Graduate School of Environmental and Human Science, Meijo University, Tempaku, Nagoya 468 8503, Japan
    Chemosphere 71:1531-8. 2008
    ..This color change is similar to the phenomenon observed when a sudden decline in growth of cyanobacteria begins in a natural environment...
  2. ncbi Engineering Bacillus subtilis for isobutanol production by heterologous Ehrlich pathway construction and the biosynthetic 2-ketoisovalerate precursor pathway overexpression
    Shanshan Li
    Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
    Appl Microbiol Biotechnol 91:577-89. 2011
    ..Under microaerobic condition, the engineered B. subtilis produced up to 2.62 g/L isobutanol in shake-flask fed-batch fermentation, which was 21.3% higher than that in batch fermentation...
  3. pmc Eosinophil as a cellular target of the ocular anti-allergic action of mapracorat, a novel selective glucocorticoid receptor agonist
    Monica Baiula
    Department of Pharmacology, University of Bologna, Bologna, Italy
    Mol Vis 17:3208-23. 2011
    ..This study assessed the anti-allergic activity of mapracorat at the ocular level and whether eosinophils and mast cells are targets of its action...
  4. ncbi In vivo ocular efficacy profile of mapracorat, a novel selective glucocorticoid receptor agonist, in rabbit models of ocular disease
    Afshin Shafiee
    Department of Preclinical Pharmacology, Pharmaceutical R and D, Bausch and Lomb, Inc, Rochester, New York, USA
    Invest Ophthalmol Vis Sci 52:1422-30. 2011
    ..The effects of topical BOL-303242-X and DEX on intraocular pressure (IOP) and body weight changes were also evaluated...
  5. ncbi Olfaction and odor discrimination are mediated by the C. elegans guanylyl cyclase ODR-1
    N D L'Etoile
    Howard Hughes Medical Institute, Department of Anatomy, University of California, San Francisco 94143, USA
    Neuron 25:575-86. 2000
    ..Olfactory discrimination is also disrupted by ODR-1 overexpression, probably by overproduction of the shared second messenger cGMP. We propose that AWC odorant signaling pathways are insulated to permit odor discrimination...
  6. ncbi A 13C nuclear magnetic resonance investigation of the metabolism of leucine to isoamyl alcohol in Saccharomyces cerevisiae
    J R Dickinson
    School of Pure and Applied Biology, University of Wales, Cardiff CF1 3TL, United Kingdom
    J Biol Chem 272:26871-8. 1997
    ....
  7. ncbi Applicability of CoA/acetyl-CoA manipulation system to enhance isoamyl acetate production in Escherichia coli
    Ravishankar V Vadali
    Department of Bioengineering, Rice University, 6100 Main Street MS 142, Houston, TX 77005, USA
    Metab Eng 6:294-9. 2004
    ..The acetate production pathway was inactivated under elevated CoA/acetyl-CoA conditions, which lead to a further increase in isoamyl acetate production...
  8. ncbi Reduced myocilin expression in cultured monkey trabecular meshwork cells induced by a selective glucocorticoid receptor agonist: comparison with steroids
    Bruce A Pfeffer
    Preclinical Pharmacology Department, Pharmaceutical Research and Development, Bausch and Lomb, Inc, Rochester, New York 14609, USA
    Invest Ophthalmol Vis Sci 51:437-46. 2010
    ..To assess in vitro myocilin (MYOC) expression in trabecular meshwork (TM) cells exposed to BOL-303242-X, a selective glucocorticoid receptor (GR) agonist (SEGRA), in comparison with dexamethasone (DEX), and prednisolone acetate (PA)...
  9. ncbi Bat2p is essential in Saccharomyces cerevisiae for fusel alcohol production on the non-fermentable carbon source ethanol
    Sung A Schoondermark-Stolk
    Department of Molecular Cell Biology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    FEMS Yeast Res 5:757-66. 2005
    ..Therefore we conclude that the expression of BAT2 is essential for 3-methyl-1-butanol formation on the non-fermentable carbon source, ethanol...
  10. pmc Mapracorat, a novel selective glucocorticoid receptor agonist, inhibits hyperosmolar-induced cytokine release and MAPK pathways in human corneal epithelial cells
    Megan E Cavet
    Pharmaceutical R and D, Bausch and Lomb, Inc, Rochester, NY 14609, USA
    Mol Vis 16:1791-800. 2010
    ..This study assessed the anti-inflammatory effects of mapracorat in an in vitro osmotic stress model which mimics some of the pathophysiological changes seen in dry eye...
  11. ncbi Isoamyl alcohol-induced morphological change in Saccharomyces cerevisiae involves increases in mitochondria and cell wall chitin content
    Kerstin Kern
    Cardiff School of Biosciences, Cardiff University, P O Box 915, Cardiff CF10 3TL, UK
    FEMS Yeast Res 5:43-9. 2004
    ..Filaments have an increased chitin content which is distributed over the majority of their surface, and is not confined to bud scars and the chitin ring between mother and daughter cells as in yeast-form cells...
  12. pmc Evolution, genomic analysis, and reconstruction of isobutanol tolerance in Escherichia coli
    Shota Atsumi
    Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095, USA
    Mol Syst Biol 6:449. 2010
    ..Interestingly, improved isobutanol tolerance did not increase the final titer of isobutanol production...
  13. pmc A novel eIF2B-dependent mechanism of translational control in yeast as a response to fusel alcohols
    M P Ashe
    Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, Manchester M60 1QD, UK
    EMBO J 20:6464-74. 2001
    ..This represents one of the key limiting steps of translation initiation and we provide evidence that fusel alcohols target eIF2B in order to bring about translational regulation...
  14. ncbi A transcriptome analysis of isoamyl alcohol-induced filamentation in yeast reveals a novel role for Gre2p as isovaleraldehyde reductase
    Michael Hauser
    Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    FEMS Yeast Res 7:84-92. 2007
    ..These results indicate a previously unsuspected and novel role for the GRE2 gene product as a suppressor of filamentation by virtue of encoding isovaleraldehyde reductase activity...
  15. pmc Olfactory CNG channel desensitization by Ca2+/CaM via the B1b subunit affects response termination but not sensitivity to recurring stimulation
    Yijun Song
    Department of Biology, The Johns Hopkins University, Baltimore, MD 21218, USA
    Neuron 58:374-86. 2008
    ....
  16. pmc Engineering of an Escherichia coli strain for the production of 3-methyl-1-butanol
    Michael R Connor
    University of California, Department of Chemical and Biomolecular Engineering, 5531 Boelter Hall, Los Angeles, CA 90095, USAdu
    Appl Environ Microbiol 74:5769-75. 2008
    ..This work demonstrates the feasibility of production of 3-methyl-1-butanol as a biofuel and shows promise in using E. coli as a host for production...
  17. ncbi An investigation of the metabolism of isoleucine to active Amyl alcohol in Saccharomyces cerevisiae
    J R Dickinson
    Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3TL, United Kingdom
    J Biol Chem 275:10937-42. 2000
    ....
  18. pmc Characterization of ZK 245186, a novel, selective glucocorticoid receptor agonist for the topical treatment of inflammatory skin diseases
    H Schäcke
    Bayer Schering Pharma, Global Drug Discovery, Berlin, Germany
    Br J Pharmacol 158:1088-103. 2009
    ..Here we report on ZK 245186, a novel, non-steroidal, low-molecular-weight, glucocorticoid receptor-selective agonist for the topical treatment of inflammatory dermatoses...
  19. pmc Nonselective suppression of voltage-gated currents by odorants in the newt olfactory receptor cells
    F Kawai
    Department of Information Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    J Gen Physiol 109:265-72. 1997
    ..The nonselective blockage of ionic channels observed here is consistent with the previous notion that the suppression of the transduction current by odorants is due to the direst blockage of transduction channels...
  20. pmc Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity
    Sydnor T Withers
    Department of Chemical Engineering, University of California, Berkeley, California, USA
    Appl Environ Microbiol 73:6277-83. 2007
    ..Expression of nudF in E. coli engineered with the mevalonate-based isopentenyl pyrophosphate biosynthetic pathway resulted in the production of isopentenol...
  21. pmc BOL-303242-X, a novel selective glucocorticoid receptor agonist, with full anti-inflammatory properties in human ocular cells
    Jin Zhong Zhang
    Pharmaceutical R and D, Bausch and Lomb Inc, Rochester, NY 14603, USA
    Mol Vis 15:2606-16. 2009
    ..Data from in vitro and in vivo studies suggest an improved side-effect profile of this compound compared to classical glucocorticoids. The aim of this study was to determine the anti-inflammatory effect of BOL-303242-X in ocular cells...
  22. ncbi The uptake of 2-methyl-3-buten-2-ol into aqueous mixed solutions of sulfuric acid and hydrogen peroxide
    Ze Liu
    Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China
    Phys Chem Chem Phys 13:2069-75. 2011
    ..Thus, the multiphase acid-catalyzed oxidation of MBO with H(2)O(2) might be a potential contributor to SOA loading...
  23. pmc 3-Methyl-1-butanol production in Escherichia coli: random mutagenesis and two-phase fermentation
    Michael R Connor
    Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095, USA
    Appl Microbiol Biotechnol 86:1155-64. 2010
    ..Investigation of the host's sensitivity to 3-methyl-1-butanol directed development of a two-phase fermentation process in which titers reached 9.5 g/L of 3-methyl-1-butanol with a yield of 0.11 g/g glucose after 60 h...
  24. ncbi Ocular pharmacokinetics of mapracorat, a novel, selective glucocorticoid receptor agonist, in rabbits and monkeys
    Joel W Proksch
    Pharmaceutical Research and Development, Bausch and Lomb, Inc, Rochester, NY 14609, USA
    Drug Metab Dispos 39:1181-7. 2011
    ..The favorable pharmacokinetic profile of mapracorat supports further clinical investigation and suggests that a convenient daily dosing regimen may be efficacious for this novel ophthalmic anti-inflammatory therapy...
  25. ncbi Photooxidation of 2-methyl-3-Buten-2-ol (MBO) as a potential source of secondary organic aerosol
    Arthur W H Chan
    Department of Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA
    Environ Sci Technol 43:4647-52. 2009
    ..Despite its structural similarity to isoprene, photooxidation of MBO is not expected to make a significant contribution to SOA formation...
  26. ncbi Rapid identification of target genes for 3-methyl-1-butanol production in Saccharomyces cerevisiae
    Sung A Schoondermark-Stolk
    Department of Molecular Cell Biology, Utrecht University, The Netherlands
    Appl Microbiol Biotechnol 70:237-46. 2006
    ..The results indicate that this is a rapid and valuable approach for identification of interesting target genes for improvement of yeast strains used in industrial processes...
  27. pmc Expanding metabolism for biosynthesis of nonnatural alcohols
    Kechun Zhang
    Department of Chemical and Biomolecular Engineering and Chemistry, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 105:20653-8. 2008
    ..This work demonstrates an approach to build artificial metabolism beyond the natural metabolic network. Nonnatural metabolites such as long chain alcohols are now included in the metabolite family of living systems...
  28. ncbi Odorant-induced hyperpolarization and suppression of cAMP-activated current in newt olfactory receptor neurons
    H Yamada
    Institute of Biological Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8572, Japan
    Chem Senses 26:25-34. 2001
    ..Given that this inhibitory effect of odorants can affect excitation caused by other odorants, we suggest that it might play a role in coding odorants in olfactory receptor neurons...
  29. pmc Enantioselectivity in Candida antarctica lipase B: a molecular dynamics study
    S Raza
    Department of Biotechnology, Royal Institute of Technology, SE-100 44 Stockholm, Sweden
    Protein Sci 10:329-38. 2001
    ..The results of this study conveyed that the use of this type of subset was viable for the analysis of structural ensembles and yielded good predictions of enantioselectivity...
  30. ncbi Odorant-specific adaptation pathways generate olfactory plasticity in C. elegans
    H A Colbert
    Department of Anatomy, University of California, San Francisco 94143 0452, USA
    Neuron 14:803-12. 1995
    ..Mutations in adp-1 and osm-9 do not diminish the ability of unadapted animals to respond to odorants, indicating that odorant sensation and odorant adaptation are distinct processes...
  31. ncbi Olfactory epithelia exhibit progressive functional and morphological defects in CF mice
    Barbara R Grubb
    CF Pulmonary Research and Treatment Center, The University of North Carolina, Chapel Hill, NC 27599 7248, USA
    Am J Physiol Cell Physiol 293:C574-83. 2007
    ..The CF mouse thus provides a novel model to examine the mechanisms of disease-associated loss of olfactory function...
  32. ncbi Chirality in anesthesia II: stereoselective modulation of ion channel function by secondary alcohol enantiomers
    Robert Brosnan
    Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, USA
    Anesth Analg 103:86-91, table of contents. 2006
    ..We recommend that enantioselectivity not be used as a test of relevance for inhaled anesthetic targets...
  33. ncbi Performance of mice in discrimination of liquor odors: behavioral evidence for olfactory attention
    Noboru Takiguchi
    Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, 1 3 1 Kagamiyama, Higashi Hiroshima, 739 8530, Japan
    Chem Senses 33:283-90. 2008
    ..Additionally, we also observed that the olfactory attention of mice could be modified through their learning experiences...
  34. ncbi [Components of the intracellular cyclic AMP system maintaining olfactory reception of amyl alcohol]
    E V Bigdai
    I P Pavlov Institute of Physiology, Russian Acad Sci, 199034, St Petersburg, Nab Makarova, 6, Russia
    Ross Fiziol Zh Im I M Sechenova 87:821-8. 2001
    ..Increase in the intracellular cAMP level is associated with adenylate cyclase activation due to G-protein stimulation by odorant coupled with it...
  35. ncbi Olfactory discrimination of structurally similar alcohols by cockroaches
    M Sakura
    Laboratory of Neuro Cybernetics, Research Institute for Electronic Science, Hokkaido University, Japan
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 188:787-97. 2002
    ..In addition, the cockroaches learned to associate a 1-hexanol solution of the highest or lowest concentration with sucrose reward but failed to learn to associate 1-hexanol of an intermediate concentration with reward...
  36. ncbi A comparison of the discriminatory ability and sensitivity of the trigeminal and olfactory systems to chemical stimuli in the tiger salamander
    W L Silver
    Wake Forest University, Winston Salem, North Carolina 27109
    J Comp Physiol A 164:55-66. 1988
    ....
  37. ncbi Higher-alcohols biorefinery: improvement of catalyst for ethanol conversion
    Edwin S Olson
    Energy and Environmental Research Center, University of North Dakota, PO Box 9018, Grand Forks, ND 58202 9018, USA
    Appl Biochem Biotechnol 113:913-32. 2004
    ..The most successful catalysts are multifunctional with basic and hydrogen transfer components...
  38. ncbi Responsivity to two odorants, androstenone and amyl acetate, and the affective impact of odors on interpersonal relationships
    John D Pierce
    School of Science and Health, Philadelphia University, Philadelphia, PA, USA
    J Comp Psychol 118:14-9. 2004
    ..Responsivity to certain odorants may be an important factor affecting human social interactions...
  39. ncbi Human odor detectability: new methodology used to determine threshold and variation
    James C Walker
    Sensory Research Institute, Florida State University, 1800 E Paul Dirac Drive, Tallahassee, FL 32306 2741 USA
    Chem Senses 28:817-26. 2003
    ....
  40. ncbi Odor exposure causes central adaptation and morphological changes in selected olfactory glomeruli in Drosophila
    J M Devaud
    Instituto Cajal, Consejo Superior de Investigaciones Cientificas, Madrid E 28002, Spain
    J Neurosci 21:6274-82. 2001
    ..Finally, the dunce mutant fails to develop behavioral adaptation as well as morphological changes in the olfactory glomeruli after exposure. These neural changes thus appear to require the cAMP signaling pathway...
  41. ncbi Odor-concentration coding in the guinea-pig piriform cortex
    T Sugai
    Department of Physiology, Kanazawa Medical University, Uchinada, Ishikawa 920 0293, Japan
    Neuroscience 130:769-81. 2005
    ....
  42. ncbi Investigations of aroma volatile biosynthesis under anoxic conditions and in different tissues of "Redchief Delicious" apple fruit (Malus domestica Borkh.)
    D R Rudell
    Tree Fruit Research Laboratory, Agricultural Research Service, United States Department of Agriculture, Wenatchee, Washington 98801 USA
    J Agric Food Chem 50:2627-32. 2002
    ....
  43. ncbi A new method for wide frequency range dynamic olfactory stimulation and characterization
    Andrew S French
    Department of Physiology and Biophysics, Dalhousie University, Halifax, Nova Scotia B3H1X5, Canada
    Chem Senses 32:681-8. 2007
    ..Frequency response functions of Drosophila electroantennograms stimulated by fruit odors were used to demonstrate a typical application of the system...
  44. ncbi The composition of surrogate alcohols consumed in Russia
    Martin McKee
    European Centre on Health of Societies in Transition, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Alcohol Clin Exp Res 29:1884-8. 2005
    ..In this population, where there is a high death rate from alcohol-related causes, including acute alcohol poisoning, it was important to know what these products contained...
  45. ncbi Cut-off phenomenon in the protective effect of alcohols against lysophosphatidylcholine-induced calcium overload
    Louis Jean Bordeleau
    Quebec Heart Institute, Laval Hospital Research Center, 2725 Chemin Ste Foy, Ste Foy, QC, Canada, G1V 4G5
    Pflugers Arch 450:292-7. 2005
    ....
  46. ncbi Reversal of elution order for profen acid enantiomers in packed-column SFC on Chiralpak AD
    Olle Gyllenhaal
    Analytical Development, Pharmaceutical and Analytical R and D, AstraZeneca R and D Molndal, Molndal, Sweden
    Chirality 17:257-65. 2005
    ..Preliminary experiments with column temperatures over the range of -15 to 45 degrees C revealed that, in a few cases, reversal took place with a change in temperature only...
  47. ncbi Olfactory behavior of swimming C. elegans analyzed by measuring motile responses to temporal variations of odorants
    Linjiao Luo
    Department of Physics, Harvard University, 17 Oxford St, Cambridge, MA 02138, USA
    J Neurophysiol 99:2617-25. 2008
    ....
  48. ncbi Solid/gas biocatalysis: an appropriate tool to study the influence of organic components on kinetics of lipase-catalyzed alcoholysis
    Fabien Letisse
    Laboratoire de Genie Proteique et Cellulaire, Pôle Sciences et Technologies, Universite de La Rochelle, Batiment Marie Curie, Avenue Michel Crepeau, 17042 La Rochelle Cedex 1, France
    Biochim Biophys Acta 1652:27-34. 2003
    ....
  49. ncbi Olfactory sensitivity for aliphatic alcohols in squirrel monkeys and pigtail macaques
    Matthias Laska
    Department of Medical Psychology, University of Munich Medical School, Goethestrasse 31, D 80336 Munich, Germany
    J Exp Biol 205:1633-43. 2002
    ..Further, our findings suggest that olfaction may play an important and hitherto underestimated role in the regulation of behaviour in the species tested...
  50. ncbi Full model for reversible kinetics of lipase-catalyzed sugar-ester synthesis in 2-methyl 2-butanol
    Maria Victoria Flores
    Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow G1 1XL, Scotland, UK
    Biotechnol Bioeng 78:795-801. 2002
    ..This reduced form of a full reversible kinetic model based on the ping-pong bi-bi mechanism is able to describe the complete course of lauroyl glucose ester synthesis. The proposed model provides a good fit for the experimental results...
  51. ncbi Influence of glucose solubility and dissolution rate on the kinetics of lipase catalyzed synthesis of glucose laurate in 2-methyl 2-butanol
    Maria Victoria Flores
    Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow G1 1XL, Scotland, UK
    Biotechnol Bioeng 78:815-21. 2002
    ..Experiments with added molecular sieves show that the main reason is the accumulation of product water. In the presence of molecular sieves, 70% of glucose was converted to ester, independent of the initial soluble glucose in the medium...
  52. pmc Olfactory-mediated fear conditioning in mice: simultaneous measurements of fear-potentiated startle and freezing
    Seth V Jones
    Department of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA
    Behav Neurosci 119:329-35. 2005
    ..Furthermore, mice were able to discriminate between an odor paired with shock and a nonreinforced odor (Experiment 4)...
  53. ncbi Molecular interaction studies of acrylic esters with 1-alcohols
    P Sivagurunathan
    Department of Physics, Annamalai University, Annamalai Nagar, Tamilnadu 608002, India
    Spectrochim Acta A Mol Biomol Spectrosc 64:127-9. 2006
    ....
  54. doi Purification and concentration of DNA from aqueous solutions
    David Moore
    Baylor College of Medicine, Houston, Texas, USA
    Curr Protoc Mol Biol . 2002
    ..The final two alternate protocols are used for concentrating RNA and extracting and precipitating DNA from larger volumes and from dilute solutions, and for removing low-molecular-weight oligonucleotides and triphosphates...
  55. ncbi Heterologous expression of the alcohol dehydrogenase (adhI) gene from Geobacillus thermoglucosidasius strain M10EXG
    Young Jae Jeon
    School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney 2052, Australia
    J Biotechnol 135:127-33. 2008
    ..In silico analysis, including phylogenetic reconstruction and protein modeling, confirmed that the thermostable enzyme from G. thermoglucosidasius is likely to belong to the NAD-Zn-dependent family of alcohol dehydrogenases...
  56. ncbi Isoform-specific enhancement of adenylyl cyclase activity by n-alkanols
    Jinghong Kou
    Department of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana 70803, USA
    Alcohol Clin Exp Res 31:1467-72. 2007
    ..These findings suggest that the target of ethanol's action in the cAMP-generating system is AC. However, it is unknown if the action of ethanol is direct or indirect...
  57. ncbi Controlled formation of volatile components in cider making using a combination of Saccharomyces cerevisiae and Hanseniaspora valbyensis yeast species
    Y Xu
    School of Biotechnology, Key Laboratory of Industrial Biotechnology, Ministry of Education, Southern Yangtze University, Wuxi, Jiangsu 214036, PR China
    J Ind Microbiol Biotechnol 33:192-6. 2006
    ..41-20.96%, and to decrease the alcohol concentration by 25.06-51.38%. Efficient control of the formation of volatile compounds was achieved by adjusting the inoculation time of the two yeasts...
  58. ncbi Dual action of n-alcohols on neuronal nicotinic acetylcholine receptors
    Y Zuo
    Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Mol Pharmacol 60:700-11. 2001
    ..These results suggest that potentiating and inhibitory actions are exerted through two different binding sites. Ethanol decreased the potency of n-octanol to inhibit ACh currents, possibly resulting from an allosteric mechanism...
  59. ncbi Comprehensive gene expression analysis of the response to straight-chain alcohols in Saccharomyces cerevisiae using cDNA microarray
    K Fujita
    Japan Bioindustry Association JBA, Daicel Chemical Industries, Ltd, Branch, Tsukuba, Japan
    J Appl Microbiol 97:57-67. 2004
    ..The purpose of this study was to examine the gene expression profiles of yeast Saccharomyces cerevisiae subjected to straight-chain alcohols...
  60. ncbi Multivariable control of alcohol concentrations in the production of polyhydroxyalkanoates (PHAs) by Paracoccus denitrificans
    S Chanprateep
    Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871 Japan
    Biotechnol Bioeng 74:116-24. 2001
    ..The combined strategy is realized using multivariable controllers and P(3HB-co-3HV) production is maximized with a given value of mole fraction of 3HV units at the final step of fermentation...
  61. ncbi Lipase-catalyzed synthesis of xylitol monoesters: solvent engineering approach
    E Castillo
    Departamento de Bioingeniería, Instituto de Biotecnologia, UNAM, Apartado Postal 510 3, Cuernavaca, Morelos 62271, Mexico
    J Biotechnol 102:251-9. 2003
    ..To our knowledge, the characterization of solvent mixtures in terms of this polarity parameter and its relationship with the selectivity of the process has not been previously reported...
  62. ncbi Economically pertinent continuous amide formation by direct lipase-catalyzed amidation with ammonia
    Wouter F Slotema
    Departement de Genie Biochimique et Alimentaire, INSA, UMR CNRS 5504, UMR INRA 792, 135 Avenue de Rangueil, 31077 Toulouse Cedex 4, France
    Biotechnol Bioeng 82:664-9. 2003
    ..The volumetric productivity, 100 g. L(-1). h(-1), is 4 to 100 times higher than in literature procedures. A simple crystallization procedure leads to 99% purity...
  63. ncbi Regular self-motion of a liquid droplet powered by the chemical marangoni effect
    Ken Nagai
    Department of Physics, Graduate School of Science, Kyoto University, Kyoto 606 8502, Japan
    Colloids Surf B Biointerfaces 56:197-200. 2007
    ..This result suggests a scenario on the emergence of regular motion coupled with geometrical pattern formation under far-from-equilibrium conditions...
  64. ncbi Caenorhabditus elegans arrestin regulates neural G protein signaling and olfactory adaptation and recovery
    Aimee Palmitessa
    Department of Microbiology and Immunology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Biol Chem 280:24649-62. 2005
    ....
  65. ncbi Characteristics of odorant elicited calcium fluxes in acutely-isolated chick olfactory neurons
    Yewah Jung
    Biology Department, University of Scranton, Scranton, PA 18510, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 191:511-20. 2005
    ..It appears that there are common features of odorant signaling shared by a variety of vertebrate species, as well as features that may be peculiar to chickens...
  66. ncbi [Kinetics of Ca2+, NADH, and oxidized flavoproteins in the frog olfactory lining under the effect of odorants]
    Ia N Rudenko
    Biofizika 52:88-94. 2007
    ..At the same time, the motor activity of olfactory cilia is depressed...
  67. ncbi A genetic dissociation of learning and recall in Caenorhabditis elegans
    Karen Atkinson-Leadbeater
    Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
    Behav Neurosci 118:1206-13. 2004
    ..Therefore, the CB4856 strain does not have an acquisition deficit, but it suffers from a recall deficit specific to benzaldehyde...
  68. ncbi Tracing odor-induced activation in the olfactory bulbs of mice using manganese-enhanced magnetic resonance imaging
    Robia G Pautler
    Department of Biological Sciences and Pittsburgh NMR Center for Biomedical Research, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    Neuroimage 16:441-8. 2002
    ..Furthermore, since the effects of activation are imaged after the activation protocol it should be possible to take the time to obtain very high resolution images and make MEMRI maps from awake behaving animals...
  69. ncbi Perceptual interactions in odour mixtures: odour quality in binary mixtures of woody and fruity wine odorants
    Boriana Atanasova
    Unité Mixte de Recherches sur les Arômes, INRA, 17 rue Sully, BP 86510, 21065 Dijon Cedex, France
    Chem Senses 30:209-17. 2005
    ..An alternative linear logistic model was proposed to study the qualitative dominance of the woody note in the three mixtures when the perceived intensities of each unmixed compound were equal...
  70. ncbi Identification of impact odorants in Bordeaux red grape juice, in the commercial yeast used for its fermentation, and in the produced wine
    Y Kotseridis
    Laboratoire des Arômes et Substances Naturelles, INRA IPV, 2 place P Viala, 34060 Montpellier, Cedex 01, France
    J Agric Food Chem 48:400-6. 2000
    ..Determination of the odor thresholds of some of these impact odorants was carried out...
  71. ncbi Structural aspects in the dielectric properties of pentyl alcohols
    Udo Kaatze
    Drittes Physikalisches Institut, Georg August Universitat, Friedrich Hund Platz 1, 37077 Gottingen, Germany
    J Chem Phys 133:094508. 2010
    ..Especially the dielectric parameters of tert-pentanol deviate significantly from the relevant parameters of the other pentanols. Such deviations are considered in the light of models of hydrogen network structure and fluctuations.
  72. pmc Enantioselective synthesis of (Z)- and (E)-2-methyl-1,5-anti-pentenediols via an allene hydroboration-double-allylboration reaction sequence
    Ming Chen
    Department of Chemistry, Scripps Florida, Jupiter, Florida 33458, United States
    J Am Chem Soc 135:9512-7. 2013
    ..Furthermore, 1,5-pentenediols 4 and 6 can be easily converted to 1,3,5-triols with excellent diastereoselectivity in one step. ..
  73. ncbi Continuous synthesis of alkyl ferulate by immobilized Candida antarctica lipase at high temperature
    Yayoi Yoshida
    Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Biotechnol Lett 28:1471-4. 2006
    ..Conversions greater than 0.9 were achieved for the synthesis of the 1-hexyl and 1-heptyl ferulates at 90 degrees C. The system could be stably operated for the 1-heptyl ferulate synthesis at 90 degrees C for at least two weeks...
  74. ncbi Applicability of Lactobacillus plantarum IMDO 788 as a starter culture to control vegetable fermentations
    Dorrit Wouters
    Research Group of Industrial Microbiology and Food Biotechnology IMDO, Department of Bioengineering Sciences, Faculty of Sciences and Bioengineering Sciences, Vrije Universiteit Brussel, Pleinlaan 2, B 1050, Brussels, Belgium
    J Sci Food Agric 93:3352-61. 2013
    ..g. in Eastern Europe. Although usually spontaneous fermentation processes are applied, the addition of lactic acid bacteria (LAB) starter cultures could accelerate processing and improve the consistency and quality of the end-products...
  75. ncbi Acetaminophen hepatotoxicity precipitated by short-term treatment of rats with ethanol and isopentanol: protection by triacetyloleandomycin
    J F Sinclair
    Veterans Administration Medical Center, White River Junction, VT 05009, USA
    Biochem Pharmacol 59:445-54. 2000
    ....
  76. ncbi Retention of aroma compounds in starch matrices: competitions between aroma compounds toward amylose and amylopectin
    G Arvisenet
    ENESAD, Laboratoire de Biochimie Alimentaire, UMR Arômes INRA ENESAD, 21 boulevard O de Serres, 21800 Quetigny, France
    J Agric Food Chem 50:7345-9. 2002
    ..The retention of aroma compounds blended in starch-based systems gave us additional information which confirmed that interactions occur not only with amylose but also with amylopectin...
  77. ncbi The biochemical origin of pentenol emissions from wounded leaves
    A J Fisher
    Department of Chemistry and Biochemistry, University of Colorado, CO 80309, Boulder, USA
    Phytochemistry 62:159-63. 2003
    ..It therefore seems likely that the C5,13-cleavage activity of LOX is the direct source of abundant pentenol and the indirect source of pentenone observed upon leaf wounding...
  78. ncbi Preparation of a fludarabine intermediate via selective alkylation of 2-fluoroadenine
    Brian E Schulmeier
    Genzyme Corporation, Therapeutics Manufacturing and Development, 14805 Omicron Dr, San Antonio, TX 78245, USA
    Nucleosides Nucleotides Nucleic Acids 25:735-45. 2006
    ..This reaction was demonstrated on gram scale as a practical laboratory synthesis of 5, a known intermediate in the synthesis of fludarabine...
  79. ncbi The role of non-Saccharomyces species in releasing glycosidic bound fraction of grape aroma components--a preliminary study
    A Mendes Ferreira
    Food Science Department, , 5001 Vila Real, Portugal
    J Appl Microbiol 91:67-71. 2001
    ..SIGNIFICANCE AND IMPACT OF THE STUDY: This study confirms the role of non-Saccharomyces species in enhancing wine aroma and flavour, suggesting that the future lies with controlled use of mixed cultures in winemaking...
  80. pmc Sequencing and characterizing odorant receptors of the cerambycid beetle Megacyllene caryae
    Robert F Mitchell
    Department of Entomology, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Insect Biochem Mol Biol 42:499-505. 2012
    ..These Ors are the first to be functionally characterized from any species of beetle and lay the groundwork for understanding the evolution of pheromones within the Cerambycidae...
  81. ncbi Effect of hydrophobically modified polymer on salt-induced structural transition in microemulsions
    Xiaojing Ma
    Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, PR China
    Langmuir 20:5679-82. 2004
    ..All results indicate that the strong interaction of surfactant with hydrophobically modified polymer has a large effect on the formation and properties of the middle-phase microemulsion...
  82. ncbi Interpersonal defensiveness and diminished perceptual acuity for the odor of a putative pheromone: androstenone
    John P Kline
    Department of Psychology, 381 Life Sciences Building, University of South Alabama, Mobile, AL 36688 0002, USA
    Biol Psychol 74:405-13. 2007
    ..The results are discussed in terms of motives to seek social approval and avoid social disapproval as they may relate to diminished awareness of androstenone...
  83. ncbi A new approach for the asymmetric total synthesis of umbelactone
    Huawei Liu
    State Key Laboratory of Applied Organic Chemistry, Institute of Organic Chemistry, Lanzhou University, Lanzhou, PR China
    Chirality 18:223-6. 2006
    ..Starting from 3-methyl-2-buten-1-ol, the asymmetric total synthesis was achieved in an efficient 6-step protocol with an overall yield of 16%...
  84. ncbi Solute-solvent interactions in micellar liquid chromatography. Characterization of hybrid micellar systems of sodium dodecyl sulfate-pentanol
    Mayte Gil-Agustí
    Area de Quimica Analitica, CCEE, ESTCE, Universitat Jaume I, Campus Riu Sec, 12080 Castelló, Spain
    J Chromatogr A 1117:47-55. 2006
    ..Conventional RPLC chromatography using mobile phases with high amounts of organic solvents are close to the micellar mobile phases that only use small amounts of alcohol...
  85. ncbi The composition of surrogate and illegal alcohol products in Estonia
    Katrin Lang
    Department of Public Health, University of Tartu, Ravila 19, 50411 Tartu, Estonia
    Alcohol Alcohol 41:446-50. 2006
    ..To identify the composition of illegal and surrogate alcohol products consumed in Estonia...
  86. ncbi Differences between isoamyl alcohol and ethanol on the metabolism and DNA ethylation of N-nitrosodiethylamine in the rat
    L F Ribeiro Pinto
    Departmento de Bioquimica, IBRAG, Universidade do Estado do Rio de Janeiro, Av 28 de Setembro, 87, Fundos 4 Andar, Vila Isabel, 20551 013, Rio de Janeiro, Brazil
    Toxicology 151:73-9. 2000
    ..42 mM), but also by esophageal epithelium (K(i)=0.52 mM), thus possessing an affinity also for the esophageal NDEA metabolizing P450...
  87. ncbi Analytical variables affecting exchangeable copper determination in blood plasma
    Wayne T Buckley
    Pacific Agriculture Research Centre, Agriculture and Agri Food Canada, Agassiz, BC, Canada
    Biometals 21:601-12. 2008
    ..Ultrafiltration of plasma yielded a Cu fraction about half that of the exchangeable Cu fraction. We conclude that the stable isotope dilution procedure for plasma exchangeable Cu yields reliable, physiologically meaningful results...
  88. ncbi Enhancing effect of alpha-hydroxyacids on "in vitro" permeation across the human skin of compounds with different lipophilicity
    A Copoví
    Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Valencia, Avd Vicente Andres Estellés, s n 46100 Burjassot, Valencia, Spain
    Int J Pharm 314:31-6. 2006
    ..The least irritant capacity corresponded to lactic acid; consequently, this alpha-hydroxyacid could be proposed as a percutaneous penetration enhancer for hydrophilic molecules that are of interest for transdermal administration...
  89. ncbi Packing properties of 1-alkanols and alkanes in a phospholipid membrane
    Thomas H Aagaard
    Department of Life Science and Chemistry, Roskilde University PO Box 260, DK 4000 Roskilde, Denmark
    Biophys Chem 119:61-8. 2006
    ..In this region, they partially occupy interstitial (or free-) volume, which bring about a denser molecular packing and generate a negative contribution to DeltaV(m)(pure-->mem)...
  90. ncbi Sulfone and phosphinic acid analogs of decaprenolphosphoarabinose as potential anti-tuberculosis agents
    Charla A Centrone
    Department of Chemistry, The Ohio State University, 100 West 18th Avenue, Columbus, OH 43210, USA
    Bioorg Med Chem 12:5495-503. 2004
    ..Screening of these compounds in vitro against Mycobacterium tuberculosis strain H(37)Rv revealed that while some of these compounds possessed low to modest activity, none was as potent as 7...
  91. ncbi New syntheses of 1,7-dimethylnonyl propanoate, the western corn rootworm pheromone, in four different ways via cross metathesis, alkylation and coupling reactions
    Kenji Mori
    Photosensitive Materials Research Center, Toyo Gosei Co, Ltd, Inba gun, Chiba, Japan
    Biosci Biotechnol Biochem 74:595-600. 2010
    ....
  92. ncbi Light conditions alter accumulation of long chain polyprenols in leaves of trees and shrubs throughout the vegetation season
    Agnieszka Bajda
    Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warszawa, Poland
    Acta Biochim Pol 52:233-41. 2005
    ..The polyprenol content of leaves shows seasonal changes with a maximum in autumn and a minimum in early summer with the difference between poorly and well illuminated plants persisting throughout the vegetation season...
  93. ncbi Preparation and properties of gelatin-immobilized beta-glucosidase from Pyrococcus furiosus
    Hidetaka Nagatomo
    Faculty of Engineering, University of Miyazaki, Miyazaki, Japan
    Biosci Biotechnol Biochem 69:128-36. 2005
    ..The immobilized enzyme was more effective than the native one in transglucosylation. The gelatin-immobilized Pfu-beta-glucosidase recovered from the first run of the reaction was reusable on successive runs...
  94. ncbi Microbial ethanol production: experimental study and multivariate evaluation
    Vassiliki A Boumba
    Department of Forensic Medicine and Toxicology, Medical School, University of Ioannina, 45110 Ioaninna, Greece
    Forensic Sci Int 215:189-98. 2012
    ..However, the models can be applied with acceptable accuracy and they show potential for application in real postmortem cases...
  95. ncbi Instability of a lamellar phase under shear flow: formation of multilamellar vesicles
    L Courbin
    Centre de Physique Moleculaire Optique et Hertzienne, UMR CNRS 5798, Universite Bordeaux I, 351 Cours de la Liberation, 33400 Talence, France
    Phys Rev Lett 89:148305. 2002
    ..These results strongly suggest that formation of multilamellar vesicles may be monitored by an undulation (buckling) instability of the membranes, as expected from theory...
  96. ncbi A common inhibitory binding site for zinc and odorants at the voltage-gated K(+) channel of rat olfactory receptor neurons
    B Seebungkert
    Department of Physiology and Pharmacology, University of Queensland, Brisbane, QLD, 4072, Australia
    Eur J Neurosci 14:353-62. 2001
    ..These observations indicate that the odorants and zinc share a common inhibitory binding site on the external surface of the voltage-gated K(+) channel...
  97. ncbi Characterization of a Saccharomyces cerevisiae mutant with pseudohyphae and cloning of a gene complementing the mutation
    Jaruwan Maneesri
    Department of Applied and Bioapplied Chemistry, Graduate School of Engineering, Osaka City University, Sugimoto 3 3 138, Sumiyoshi ku, Osaka 558 8585, Japan
    Biosci Biotechnol Biochem 67:517-24. 2003
    ..Sequencing of J19 SCL1 showed that the glycine at position 226 in the Scl1 protein had been replaced by asparatic acid, suggesting that this mutation in the protein, a subunit of proteasomes, may be involved in the morphological change...
  98. ncbi Fragrance material review on 2-methyl-4-phenylpentanol
    J Scognamiglio
    Research Institute for Fragrance Materials, Inc, 50 Tice Boulevard, Woodcliff Lake, NJ 07677, USA
    Food Chem Toxicol 50:S209-14. 2012
    ..2012) for an overall assessment of the safe use of this material and all Aryl Alkyl Alcohols in fragrances...
  99. ncbi Analysis of the Frz signal transduction system of Myxococcus xanthus shows the importance of the conserved C-terminal region of the cytoplasmic chemoreceptor FrzCD in sensing signals
    Víctor H Bustamante
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720 3204, USA
    Mol Microbiol 53:1501-13. 2004
    ..Thus, signal input to the Frz system must be sensed by the conserved C-terminal module of FrzCD and not the usual N-terminal region. These results indicate an alternative mechanism for signal sensing with this cytoplasmic MCP...
  100. ncbi Olfactory detection thresholds and pleasantness of a food-related and a non-food odour in hunger and satiety
    J Albrecht
    Department of Neuroradiology, Ludwig Maximilians University Munich, Germany
    Rhinology 47:160-5. 2009
    ..Instead our findings that satiety decreases the pleasantness of a food-related odour support the hypothesis that both odour threshold as well as pleasantness play an important role in the control of food intake...
  101. ncbi The occurrence of polyprenols in seeds and leaves of woody plants
    Marcin Chouda
    Agricultural University, SGGW, Warszawa, Poland
    Acta Biochim Pol 52:243-53. 2005
    ..In angiosperms (25 representatives of 13 botanical families) the polyisoprenoid mixture in seeds resembled the minor, additional subfamily found in leaves...

Research Grants9

  1. Alcohol and Acetaminophen Hepatotoxicity
    Jacqueline Sinclair; Fiscal Year: 2006
    ..2. To investigate the effect of methylxanthines, which increase CYP3A activity but decrease CYP1A2, on alcohol-mediated APAP hepatotoxicity in wild-type and CYP1A2 knockout mice. ..
  2. STUDIES OF ADULT BRAIN NEUROPOIESIS
    Dennis Steindler; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  3. Altering Fate of Hematopoietic and Neural Stem Cells
    Dennis Steindler; Fiscal Year: 2006
    ..abstract_text> ..
  4. REDUCED DRUG INTERACTIONS OF AZOLE ANTIFUNGAL DRUGS
    Joseph Gal; Fiscal Year: 2003
    ..abstract_text> ..
  5. Psychoneuroimmunology and Mind-Body Medicine
    Janice Kiecolt Glaser; Fiscal Year: 2005
    ..Accordingly, a psychoneuroimmunology focus for these mechanistic studies will provide a way to clarify mechanisms while assessing clinical efficacy. ..
  6. Psychoneuroimmunology and Mind-Body Interventions
    Janice Kiecolt Glaser; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  7. Metabolic Engineering to Overcome N-Glycosylation Deficiency in Mammalian Cells
    Michael Betenbaugh; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  8. Gating Mechanisms of CLC Chloride Channels
    Tsung Yu Chen; Fiscal Year: 2008
    ..abstract_text> ..