famotidine

Summary

Summary: A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.

Top Publications

  1. ncbi Effects of three H2-receptor antagonists (cimetidine, famotidine, ranitidine) on serum gastrin level
    T Ohsawa
    Chidoribashi Hospital Pharmacy, Department of Pharmacokinetics, Faculty of Pharmaceutical Science, Kyushu University, Fukuoka, Japan
    Int J Clin Pharmacol Res 22:29-35. 2002
  2. ncbi Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarction
    Fook Hong Ng
    Department of Medicine and Geriatric, Ruttonjee Hospital, Hong Kong, China
    Am J Gastroenterol 107:389-96. 2012
  3. ncbi Hepatoprotective, antinociceptive and antioxidant activities of cimetidine, ranitidine and famotidine as histamine H2 receptor antagonists
    Amirhossein Ahmadi
    Student Research Committee, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
    Fundam Clin Pharmacol 25:72-9. 2011
  4. ncbi Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions
    Fook Hong Ng
    Department of Medicine and Geriatric, Ruttonjee Hospital, Hong Kong, China
    Gastroenterology 138:82-8. 2010
  5. pmc Efficacy of omeprazole, famotidine, mosapride and teprenone in patients with upper gastrointestinal symptoms: an omeprazole-controlled randomized study (J-FOCUS)
    Kouichi Sakurai
    Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto 860 8556, Japan
    BMC Gastroenterol 12:42. 2012
  6. ncbi Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3)
    David L Bourdet
    Division of Drug Delivery and Disposition, School of Pharmacy, Kerr Hall, CB 7360, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7360, USA
    J Pharmacol Exp Ther 315:1288-97. 2005
  7. ncbi Protective effect of famotidine, omeprazole, and melatonin against acetylsalicylic acid-induced gastric damage in rats
    G Sener-Muratoğlu
    Marmara University School of Pharmacy, Department of Pharmacology, Haydarpasa, Istanbul, Turkey
    Dig Dis Sci 46:318-30. 2001
  8. ncbi Influence of lansoprazole, famotidine, roxatidine and rebamipide administration on the urea breath test for the diagnosis of Helicobacter pylori infection
    Kyoichi Adachi
    Department of Internal Medicine II, Shimane Medical University, Izumo, Japan
    J Gastroenterol Hepatol 18:168-71. 2003
  9. pmc Double-blind randomized trials of single-tablet ibuprofen/high-dose famotidine vs. ibuprofen alone for reduction of gastric and duodenal ulcers
    Loren Laine
    Division of Gastrointestinal and Liver Diseases, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Am J Gastroenterol 107:379-86. 2012
  10. ncbi Influence of famotidine on verapamil pharmacokinetics in rats
    Kamal M Matar
    Department of Applied Therapeutics, Faculty of Pharmacy, Kuwait University, Kuwait
    Eur J Drug Metab Pharmacokinet 30:219-22. 2005

Research Grants

  1. AGE-RELATED GASTRIC CHANGES AND DRUG ABSORPTION
    Aryeh Hurwitz; Fiscal Year: 1993
  2. PREVENTION OF ULCER HEMORRHAGE BY H PYLORI ERADICATION
    Dennis Jensen; Fiscal Year: 2000
  3. Two Photon Microscope
    Marshall Montrose; Fiscal Year: 2005
  4. SUBCELLULAR REGULATION OF COLONIC ION TRANSPORTERS
    Marshall Montrose; Fiscal Year: 2005
  5. Innovations in Gastrointestinal Research and Therapy: FASEB summer conference
    Marshall Montrose; Fiscal Year: 2005
  6. Arcturus Veritas Microdissection Microscope
    Marshall Montrose; Fiscal Year: 2006
  7. Gastrointestinal Response to Injury: Canada 2007
    Marshall Montrose; Fiscal Year: 2007
  8. THE ROLE OF MYCOBACTERIA IN CROHN'S DISEASE
    David Graham; Fiscal Year: 2005
  9. Helicobacter pylori: Pathogenesis and Virulence
    Kenneth Simpson; Fiscal Year: 2005

Detail Information

Publications234 found, 100 shown here

  1. ncbi Effects of three H2-receptor antagonists (cimetidine, famotidine, ranitidine) on serum gastrin level
    T Ohsawa
    Chidoribashi Hospital Pharmacy, Department of Pharmacokinetics, Faculty of Pharmaceutical Science, Kyushu University, Fukuoka, Japan
    Int J Clin Pharmacol Res 22:29-35. 2002
    ..The subjects were 51 patients (cimetidine: 18 patients; famotidine: 16 patients; ranitidine: 17 patients)...
  2. ncbi Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarction
    Fook Hong Ng
    Department of Medicine and Geriatric, Ruttonjee Hospital, Hong Kong, China
    Am J Gastroenterol 107:389-96. 2012
    ..The objective of this study was to compare the efficacies of esomeprazole and famotidine in preventing gastrointestinal complications.
  3. ncbi Hepatoprotective, antinociceptive and antioxidant activities of cimetidine, ranitidine and famotidine as histamine H2 receptor antagonists
    Amirhossein Ahmadi
    Student Research Committee, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
    Fundam Clin Pharmacol 25:72-9. 2011
    ..The hepatoprotective effects of cimetidine, ranitidine and famotidine against hepatotoxicity induced by carbon tetrachloride (CCl(4) ) were determined by measuring the levels of ..
  4. ncbi Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions
    Fook Hong Ng
    Department of Medicine and Geriatric, Ruttonjee Hospital, Hong Kong, China
    Gastroenterology 138:82-8. 2010
    ..We compared the efficacy of high-dose famotidine with that of pantoprazole in preventing recurrent symptomatic ulcers/erosions.
  5. pmc Efficacy of omeprazole, famotidine, mosapride and teprenone in patients with upper gastrointestinal symptoms: an omeprazole-controlled randomized study (J-FOCUS)
    Kouichi Sakurai
    Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto 860 8556, Japan
    BMC Gastroenterol 12:42. 2012
    ..In Japan, treatment guidelines are lacking for patients with upper gastrointestinal symptoms. We aimed to compare the efficacy of different drugs for the treatment of uninvestigated upper gastrointestinal symptoms...
  6. ncbi Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3)
    David L Bourdet
    Division of Drug Delivery and Disposition, School of Pharmacy, Kerr Hall, CB 7360, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7360, USA
    J Pharmacol Exp Ther 315:1288-97. 2005
    ..this study was to evaluate the substrate and inhibitory activity of the H2-receptor antagonists ranitidine and famotidine toward hOCTs and to determine the hOCT isoforms involved in the absorption and elimination of these compounds in ..
  7. ncbi Protective effect of famotidine, omeprazole, and melatonin against acetylsalicylic acid-induced gastric damage in rats
    G Sener-Muratoğlu
    Marmara University School of Pharmacy, Department of Pharmacology, Haydarpasa, Istanbul, Turkey
    Dig Dis Sci 46:318-30. 2001
    It has been reported that both omeprazole and famotidine have a protective effect against gastric mucosal damage induced by acetylsalicylic acid (ASA) and other nonsteroidal anti-inflammatory drugs...
  8. ncbi Influence of lansoprazole, famotidine, roxatidine and rebamipide administration on the urea breath test for the diagnosis of Helicobacter pylori infection
    Kyoichi Adachi
    Department of Internal Medicine II, Shimane Medical University, Izumo, Japan
    J Gastroenterol Hepatol 18:168-71. 2003
    ..The aim of this study is to clarify the effects of lansoprazole, famotidine, roxatidine and rebamipide administration on UBT sensitivity.
  9. pmc Double-blind randomized trials of single-tablet ibuprofen/high-dose famotidine vs. ibuprofen alone for reduction of gastric and duodenal ulcers
    Loren Laine
    Division of Gastrointestinal and Liver Diseases, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Am J Gastroenterol 107:379-86. 2012
    ..Ulcer Formation of HZT-501 Compared with Ibuprofen: Efficacy and Safety Studies)) to assess whether double-dose famotidine given in a single-tablet combination with ibuprofen (HZT-501) significantly reduces gastric and duodenal ulcers ..
  10. ncbi Influence of famotidine on verapamil pharmacokinetics in rats
    Kamal M Matar
    Department of Applied Therapeutics, Faculty of Pharmacy, Kuwait University, Kuwait
    Eur J Drug Metab Pharmacokinet 30:219-22. 2005
    The effect of famotidine (4 mg/kg, p.o.) on the kinetic profile of co-administered verapamil (20 mg/kg(-1), p.o.) was studied in the rat. Plasma verapamil levels were collected serially for 12 h and measured using sensitive HPLC method...
  11. ncbi Double-blind, placebo-controlled trial of famotidine in children with abdominal pain and dyspepsia: global and quantitative assessment
    M C See
    Department of Pediatrics, Mount Sinai Medical Center, New York, New York 10029, USA
    Dig Dis Sci 46:985-92. 2001
    ..with abdominal pain and dyspepsia, 25 such children were enrolled in a double-blind, placebo-controlled trial of famotidine. Global and quantitative pain assessments were done before and after each treatment period...
  12. ncbi In vivo gamma-rays induced initial DNA damage and the effect of famotidine in mouse leukocytes as assayed by the alkaline comet assay
    Hossein Mozdarani
    Dept of Medical Genetics, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran
    J Radiat Res 48:129-34. 2007
    ..To assess gamma ray-induced DNA damage in vivo in mouse leukocytes at various doses and the effect of famotidine, blood was collected from Balb/c male mice after irradiation with 4 Gy gamma-rays at different time intervals ..
  13. ncbi Mechanochemical synthesis and in vitro anti-Helicobacter pylori and uresase inhibitory activities of novel zinc(II)-famotidine complex
    Muhammad Amin
    Department of Chemistry, University of Sargodha, Sargodha, Pakistan
    J Enzyme Inhib Med Chem 25:383-90. 2010
    The mechanochemical synthesis and characterization of a zinc complex with famotidine is described. The complex was characterized by microanalysis and a number of spectroscopic techniques. The complex was of M:L dihydrate type...
  14. ncbi Assessing the efficacy of famotidine and rebamipide in the treatment of gastric mucosal lesions in patients receiving long-term NSAID therapy (FORCE--famotidine or rebamipide in comparison by endoscopy)
    Jun ichi Yamao
    Third Department of Internal Medicine, Nara Medical University, 840 Shijocho, Kashihara 634 8512, Japan
    J Gastroenterol 41:1178-85. 2006
    ..In this study, we compare the effects of famotidine and rebamipide on NSAID-associated gastric mucosal lesions using upper gastrointestinal endoscopy.
  15. ncbi New strategy of therapy for functional dyspepsia using famotidine, mosapride and amitriptyline
    M Otaka
    Department of Internal Medicine, Akita University School of Medicine, Hondu, Akita, Japan
    Aliment Pharmacol Ther 21:42-6. 2005
    ..As a therapy for IBS patients, the effectiveness of antidepressants has been reported...
  16. ncbi Comparison of the efficacy of irsogladine maleate and famotidine for the healing of gastric ulcers after Helicobacter pylori eradication therapy: a randomized, controlled, prospective study
    Kazunari Murakami
    Department of Gastroenterology, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama machi, Yufu, Oita, Japan
    Scand J Gastroenterol 46:287-92. 2011
    ..pylori eradication therapy. We therefore compared the efficacy of irsogladine with famotidine as appropriate treatments for ulcers after eradication therapy.
  17. ncbi Evaluation of the disintegration properties of commercial famotidine 20 mg orally disintegrating tablets using a simple new test and human sensory test
    Tsutomu Harada
    Formulation Research Laboratories, Kawashima Research, Eisai Co Ltd, 1 Kawashimatakahaya machi, Kakamigahara, Gifu 501 6195, Japan
    Chem Pharm Bull (Tokyo) 54:1072-5. 2006
    ..Eight types of commercial famotidine 20 mg orally disintegrating tablets with different physical properties (formulation, manufacturing method, ..
  18. ncbi Concomitant dosing of famotidine with a triple therapy increases the cure rates of Helicobacter pylori infections in patients with the homozygous extensive metabolizer genotype of CYP2C19
    K Okudaira
    Second Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan
    Aliment Pharmacol Ther 21:491-7. 2005
    ..Proton-pump inhibitors, such as lansoprazole, are metabolized in the liver by CYP2C19 and cannot inhibit acid sufficiently in homozygous extensive metabolizers of CYP2C19...
  19. ncbi Effect of esomeprazole versus famotidine on platelet inhibition by clopidogrel: a double-blind, randomized trial
    Prabowo Tunggal
    Department of Medicine and Geriatrics, Ruttonjee Hospital, Hong Kong, China
    Am Heart J 162:870-4. 2011
    ..It is unknown whether famotidine, a histamine 2 receptor antagonist, interacts with clopidogrel...
  20. ncbi Comparative study of nizatidine and famotidine for maintenance therapy of erosive esophagitis
    Naoharu Hamamoto
    Department of Gastroenterology and Hepatology, Shimane University, School of Medicine, 89 1 Enya cho, Izumo shi, Shimane 693 8501, Japan
    J Gastroenterol Hepatol 20:281-6. 2005
    ..present multicenter, randomized controlled study was performed to investigate whether nizatidine is superior to famotidine, which does not suppress acetylcholine esterase activity, in maintenance therapy for erosive esophagitis...
  21. ncbi The effect of famotidine addition on olanzapine-induced weight gain in first-episode schizophrenia patients: a double-blind placebo-controlled pilot study
    Michael Poyurovsky
    Research Unit, Tirat Carmel Mental Health Center, 9 Eshkol Street, 30200 Tirat Carmel, Israel
    Eur Neuropsychopharmacol 14:332-6. 2004
    ..In this double-blind placebo-controlled study we evaluated whether the H2 antagonist famotidine may prevent/attenuate olanzapine-induced weight gain...
  22. ncbi Secretory transport of ranitidine and famotidine across Caco-2 cell monolayers
    Kiho Lee
    Division of Drug Delivery and Disposition, School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7360, USA
    J Pharmacol Exp Ther 303:574-80. 2002
    The secretory transport of the H(2)-antagonists, ranitidine and famotidine, across Caco-2 cell monolayers was found to be a saturable process...
  23. ncbi Effects of ranitidine, famotidine, pantoprazole, and omeprazole on intragastric pH in dogs
    Alexa M E Bersenas
    Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada
    Am J Vet Res 66:425-31. 2005
    ..To identify the normal gastric acid secretion profile in dogs and determine the degree of gastric acid suppression associated with 4 gastric acid suppressants...
  24. ncbi Capillary zone electrophoresis method for the determination of famotidine and related impurities in pharmaceuticals
    N Helali
    Institut National des Sciences Appliquées et de Technologie, Laboratoire de Chimie Analytique et Electrochimie 04UR12 01, Centre Urbain Nord, B P No 676, 1080 Tunis Cedex, Tunisia
    Talanta 74:694-8. 2008
    ..rapid capillary zone electrophoresis (CZE) method with UV detection has been developed for the determination of famotidine and its potential impurities in pharmaceutical formulations...
  25. ncbi Does famotidine enhance tumor infiltrating lymphocytes in breast cancer? Results of a randomized prospective pilot study
    Rajinder Parshad
    Department of Surgery, All India Institute of Medical Sciences, New Delhi
    Acta Oncol 41:362-5. 2002
    Thirty patients with breast cancer were prospectively randomized into case and control groups receiving 40 mg famotidine preoperatively for 10-14 days and routine premedication, respectively...
  26. pmc Effects of the H2-receptor antagonist famotidine on the pharmacokinetics of atazanavir-ritonavir with or without tenofovir in HIV-infected patients
    Xiaodong Wang
    Bristol Myers Squibb, Research and Development, Princeton, New Jersey, USA
    AIDS Patient Care STDS 25:509-15. 2011
    ..In healthy subjects, famotidine, an H(2)-receptor antagonist, reduces exposures of atazanavir by 4-28% at doses of 20-40 mg twice daily...
  27. ncbi Famotidine for the prevention of peptic ulcers and oesophagitis in patients taking low-dose aspirin (FAMOUS): a phase III, randomised, double-blind, placebo-controlled trial
    Ali S Taha
    Gastroenterology Unit, Crosshouse Hospital, University of Glasgow, Kilmarnock, UK
    Lancet 374:119-25. 2009
    ..We therefore investigated the efficacy of famotidine, a well-tolerated histamine H(2)-receptor antagonist, in the prevention of peptic ulcers and erosive ..
  28. ncbi The comparative effects of single intravenous doses of omeprazole and famotidine on intragastric pH
    Yasunobu Abe
    The Third Department of Internal Medicine, Yokohama City University School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama 236 0004, Japan
    J Gastroenterol 39:21-5. 2004
    ..The aim of our study was to investigate the inhibitory effects on gastric acid secretion after single intravenous administrations of omeprazole 20mg and famotidine 20 mg.
  29. ncbi Comparison of lansoprazole and famotidine for gastric acid inhibition during the daytime and night-time in different CYP2C19 genotype groups
    N Shirai
    First Department of Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan
    Aliment Pharmacol Ther 16:837-46. 2002
    The acid inhibitory effect of lansoprazole depends on the S-mephenytoin 4'-hydroxylase (CYP2C19) genotype status. The effect of famotidine is independent of this genotype.
  30. ncbi Comparison of an increased dosage regimen of rabeprazole versus a concomitant dosage regimen of famotidine with rabeprazole for nocturnal gastric acid inhibition in relation to cytochrome P450 2C19 genotypes
    Mitsushige Sugimoto
    First Department of Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan
    Clin Pharmacol Ther 77:302-11. 2005
    ..We compared the effectiveness of an increased dosage regimen of rabeprazole with that of a concomitant dosage regimen of rabeprazole with famotidine, relative to cytochrome P450 (CYP) 2C19 genotype status, on nocturnal acid inhibition.
  31. ncbi Enhancement of famotidine dissolution rate through liquisolid tablets formulation: in vitro and in vivo evaluation
    Rania H Fahmy
    Department of Pharmaceutics and Industrial Pharmacy, Cairo University, Cairo, Egypt
    Eur J Pharm Biopharm 69:993-1003. 2008
    Although famotidine was reported to be 7.5 and 20 times more potent than ranitidine and cimetidine, respectively, its oral bioavailability is low and variable; due mainly to its poor aqueous solubility...
  32. ncbi Preventive effects of lansoprazole and famotidine on gastric mucosal injury induced by low-dose aspirin in Helicobacter pylori-negative healthy volunteers
    Masafumi Nishino
    First Department of Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan
    J Clin Pharmacol 51:1079-86. 2011
    The preventive effects of lansoprazole and famotidine on low-dose aspirin-induced gastric mucosal injury in relation to gastric acidity were compared in healthy Japanese volunteers...
  33. pmc A prospective randomized trial of either famotidine or pantoprazole for the prevention of bleeding after endoscopic submucosal dissection
    Hye Kyong Jeong
    Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea
    J Korean Med Sci 22:1055-9. 2007
    ..patients undergoing ESD due to gastric adenoma or adenocarcinoma were randomly assigned to pantoprazole or famotidine. Both drugs were given intravenously for the first 2 days, thereafter by mouth...
  34. ncbi New colorimetric methods for the determination of trazodone HCl, famotidine, and diltiazem HCl in their pharmaceutical dosage forms
    Magda M Ayad
    Analytical Chemical Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt
    Anal Bioanal Chem 376:710-4. 2003
    Two sensitive and simple spectrophotometric methods are developed for the determination of trazodone HCl, famotidine, and diltiazem HCl in pure and pharmaceutical preparations...
  35. ncbi Kinetic spectrophotometric determination of famotidine in commercial dosage forms
    Nafisur Rahman
    Analytical Research Division, Department of Chemistry, Aligarh Muslim University, Aligarh U P 202002, India
    Anal Sci 19:907-11. 2003
    A simple kinetic spectrophotometric method is described for the determination of famotidine. The method is based on the oxidation of the drug with alkaline potassium permanganate...
  36. ncbi Simultaneous determination of cimetidine, famotidine, nizatidine, and ranitidine in tablets by capillary zone electrophoresis
    S M Wu
    School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, ROC, Taiwan
    Electrophoresis 22:2758-62. 2001
    ..capillary zone electrophoresis (CZE) method is described for the simultaneous determination of cimetidine (CIM), famotidine (FAM), nizatidine (NIZ), and ranitidine (RAN)...
  37. ncbi Famotidine vs. omeprazole: a prospective randomized multicentre trial to determine efficacy in non-erosive gastro-oesophageal reflux disease
    Y Fujiwara
    Department of Gastroenterology, Osaka City University Graduate School of Medicine, Asahimachi, Osaka, Japan
    Aliment Pharmacol Ther 21:10-8. 2005
    ..The efficacy of acid-suppressive drugs for non-erosive gastro-oesophageal reflux disease in Japan, in which the prevalence of Helicobacter pylori infection is higher compared with Western countries, is unknown...
  38. ncbi Development of a rapid HPLC method for determination of famotidine in human plasma using a monolithic column
    A Zarghi
    Department of Pharmaceutical Chemistry, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, No 105, Shams Alley, Vali e Asr Ave, Across from Tavanir St, P O Box 14155 6153, Tehran, Iran
    J Pharm Biomed Anal 39:677-80. 2005
    A rapid and sensitive HPLC method using a monolithic column has been developed for quantification of famotidine in plasma...
  39. ncbi Stability indicating method for famotidine in pharmaceuticals using porous graphitic carbon column
    Nawel Helali
    Institut National des Sciences Appliquées et de Technologie, Centre Urbain Nord, Tunis Cedex, Tunisia
    J Sep Sci 31:276-82. 2008
    A simple, sensitive and rapid HPLC method was developed and validated for the simultaneous determination of famotidine (FMT) and related impurities in pharmaceuticals...
  40. pmc Preparation and evaluation of taste masked famotidine formulation using drug/beta-cyclodextrin/polymer ternary complexation approach
    Ashok R Patel
    Centre for Novel Drug Delivery Systems, Department of Pharmaceutical Sciences, University Institute of Chemical Technology, Matunga, Mumbai 400019, India
    AAPS PharmSciTech 9:544-50. 2008
    ..For this purpose famotidine with property of bitter taste was selected as a model drug...
  41. ncbi Early effects of intravenous administrations of lansoprazole and famotidine on intragastric pH
    Hiroshi Iida
    Gastroenterology Division, Yokohama City University Hospital, 3 9 Fukuura, Kanazawa Ku, Yokohama Kanagawa, 236 0004, Japan
    Hepatogastroenterology 56:551-4. 2009
    ..The aim of our study was to investigate the inhibitory effects on gastric acid secretion after single intravenous administrations of lansoprazole 30 mg and famotidine 20 mg.
  42. ncbi Application of ninhydrin to spectrophotometric determination of famotidine in drug formulations
    Nafisur Rahman
    Department of Chemistry, Analytical Chemistry Division, Aligarh Muslim University, 202 002 Aligarh, India
    Farmaco 58:1045-50. 2003
    A simple and fast spectrophotometric procedure has been developed for the determination of famotidine. The method is based on the interaction of ninhydrin with primary amines present in the famotidine...
  43. ncbi A study on the nickel II-famotidine complexes
    Malgorzata Baranska
    Faculty of Chemistry, Jagiellonian University, 3 Ingardena Str, 30 060 Cracow, Poland
    J Inorg Biochem 92:112-20. 2002
    Potentiometric studies have shown that Ni(II) forms three pH-dependent complexes with famotidine (L), namely: [NiHL](3+), [NiL](2+) and [NiH(-2)L]. Two of them have been isolated from solution with a Ni/famotidine ratio of 1:1. At pH 6...
  44. ncbi Determination of famotidine in low-volume human plasma by normal-phase liquid chromatography/tandem mass spectrometry
    L Zhong
    Department of Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania 19486, USA
    J Mass Spectrom 36:736-41. 2001
    ..procedure using liquid chromatography coupled with tandem mass spectrometry (LC/MS/MS) for the determination of famotidine in human plasma and urine is described...
  45. ncbi Quantitative determination of famotidine through charge-transfer complexation with chloranilic acid
    B K Chukwurah
    Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria
    Boll Chim Farm 140:354-60. 2001
    Quantitative determination of famotidine and its dosage forms was carried out spectrophotometrically, analysing the coloured complex resulting from a charge-transfer interaction between the drug as an electron-donor and chloranilic acid ..
  46. ncbi Optimization and validation of a dissolution test for famotidine tablets using flow injection analysis
    Paraskevas D Tzanavaras
    Quality Control Department, Cosmopharm Ltd, P O Box 42, Korinthos 20100, Greece
    J Pharm Biomed Anal 41:437-41. 2006
    A dissolution test for famotidine tablets was optimized and validated using flow injection analysis (FIA)...
  47. ncbi Validated HPTLC method for simultaneous quantitation of paracetamol, diclofenac potassium, and famotidine in tablet formulation
    Laxman D Khatal
    Bharati Vidyapeeth University, Poona College of Pharmacy, Department of Pharmaceutical Chemistry, Pune, Maharashtra, India 411038
    J AOAC Int 93:765-70. 2010
    ..simple, selective, precise, and accurate HPTLC method of analysis for paracetamol, diclofenac potassium, and famotidine both as a bulk drug and in tablet formulation was developed and validated...
  48. ncbi Comparison of amoxicillin-metronidazole plus famotidine or lansoprazole for amoxicillin-clarithromycin-proton pump inhibitor treatment failures for Helicobacter pylori infection
    Kazunari Murakami
    Department of Gastroenterology, Faculty of Medicine, Oita University, 1 1 Idaigaoka Hasama, Oita 879 5593, Japan
    Helicobacter 11:436-40. 2006
    ..The authors assessed the efficacy and safety of second-line eradication using the H2-receptor antagonist famotidine as a substitute for proton pump inhibitor.
  49. ncbi Potentiometric determination of famotidine in pharmaceutical formulations
    Magda M Ayad
    Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt
    J Pharm Biomed Anal 29:247-54. 2002
    Two new potentiometric methods for determination of famotidine in pure form and in its pharmaceutical tablet form are developed...
  50. ncbi Spectrofluorimetric determination of famotidine in pharmaceutical preparations and biological fluids. Application to stability studies
    M I Walash
    Department of Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt
    J Fluoresc 19:333-44. 2009
    ..economic, selective, and stability indicating spectrofluorimetric method was developed for the determination of famotidine (FMT); is based on its reaction with 9, 10-phenanthraquinone in alkaline medium to give a highly fluorescent ..
  51. ncbi Coagulation-dependent gene expression and liver injury in rats given lipopolysaccharide with ranitidine but not with famotidine
    James P Luyendyk
    Department of Pharmacology and Toxicology, Center for Integrative Toxicology, National Food Safety and Toxicology Center, Michigan State University, East Lansing, MI 48824, USA
    J Pharmacol Exp Ther 317:635-43. 2006
    ..lipopolysaccharide (LPS) and ranitidine (RAN) develop hepatocellular injury, whereas rats treated with LPS and famotidine (FAM) do not...
  52. ncbi The effect of famotidine on gastroesophageal and duodeno-gastro-esophageal refluxes in critically ill patients
    Ying Xin
    Department of Gastroenterology, Sir Run Run Shaw Hospital, Hangzhou 310016, Zhejiang Province, China
    World J Gastroenterol 9:356-8. 2003
    To investigate the effect of famotidine on gastroesophageal reflux (GER) and duodeno-gastro-esophageal reflux (DGER) and to explore it's possible mechanisms. To identify the relevant factors of the reflux.
  53. ncbi Unique gene expression and hepatocellular injury in the lipopolysaccharide-ranitidine drug idiosyncrasy rat model: comparison with famotidine
    James P Luyendyk
    Department of Pharmacology and Toxicology, Center for Integrative Toxicology, National Food Safety and Toxicology Center, Michigan State University, East Lansing, Michigan 48824, USA
    Toxicol Sci 90:569-85. 2006
    Rats cotreated with lipopolysaccharide (LPS) and ranitidine (RAN) but not LPS and famotidine (FAM) develop hepatocellular injury in an animal model of idiosyncratic drug reactions...
  54. ncbi Interaction between famotidine and neuromuscular blockers: an in vivo study in rats
    Y Mishra
    Pharmacy Department, University of Sydney, New South Wales, Australia
    Anesth Analg 77:780-3. 1993
    The effect of histamine 2-antagonist famotidine on neuromuscular paralysis induced with either nondepolarizing or depolarizing neuromuscular blocking drugs was examined in anesthetized and mechanically ventilated rats...
  55. ncbi Efficacy of camostat mesilate compared with famotidine for treatment of functional dyspepsia: is camostat mesilate effective?
    Nobuo Ashizawa
    Department of Gastroenterology, Tamatsukuri Kousei Nenkin Hospital, Yatsuka, Japan
    J Gastroenterol Hepatol 21:767-71. 2006
    ..The aim of this study was to examine the potential efficacy of camostat mesilate, a protease inhibitor, against functional dyspepsia and to characterize patients with favorable responses...
  56. ncbi Lafutidine, a newly developed antiulcer drug, elevates postprandial intragastric pH and increases plasma calcitonin gene-related peptide and somatostatin concentrations in humans: comparisons with famotidine
    Tomohiko Shimatani
    Department of General Medicine, Hiroshima University Hospital, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Dig Dis Sci 51:114-20. 2006
    ..aged 23-32 years without Helicobacter pylori infection were orally administered either 10 mg lafutidine, 20 mg famotidine, or water only (control) 30 min after a standard meal (650 kcal)...
  57. ncbi Famotidine for infant gastro-oesophageal reflux: a multi-centre, randomized, placebo-controlled, withdrawal trial
    S R Orenstein
    Pediatric Gastroenterology, University of Pittsburgh School of Medicine, Children s Hospital of Pittsburgh, Pittsburgh, PA 15213 2583, USA
    Aliment Pharmacol Ther 17:1097-107. 2003
    ..Gastro-oesophageal reflux afflicts up to 7% of all infants. Histamine-2 receptor antagonists are the most commonly prescribed medications for this disorder, but few controlled studies support this practice...
  58. ncbi Stability of metronidazole, tetracycline HCl and famotidine alone and in combination
    Yunqi Wu
    Product Development, SCOLR Pharma, Inc, Bellevue, Washington, USA
    Int J Pharm 290:1-13. 2005
    Metronidazole, tetracycline HCl and famotidine are commonly used for the treatment of Helicobacter pylori-associated peptic ulcer...
  59. pmc Effects of the histamine H2 receptor antagonist famotidine on the healing of colonic anastomosis in rats
    Aydin Inan
    School of Medicine, Fatih University, Ankara, Turkiye
    Clinics (Sao Paulo) 64:567-70. 2009
    ..Because histamine plays an important role in immune and inflammatory reactions, we demonstrate the effects of famotidine on the healing of colonic anastomosis in rats.
  60. ncbi Comparison of the effects of omeprazole and famotidine in treatment of upper abdominal symptoms in patients with reflux esophagitis
    Hiroaki Kusunoki
    Department of General Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701 0192, Japan
    J Gastroenterol 44:261-70. 2009
    ..The purpose of this study was to compare the efficacy of proton pump inhibitor (PPI) with H(2) receptor antagonist (H(2)RA) in treatment of upper abdominal symptoms...
  61. ncbi Famotidine and long QT syndrome
    Ken W Lee
    Division of Cardiology, Cardiac Electrophysiology Section, University of California at San Francisco, 500 Parnassus Avenue, MU East 4, Box 1354, San Francisco, CA 94143, USA
    Am J Cardiol 93:1325-7. 2004
    ..However, the association of famotidine and acquired long QT syndrome has rarely been reported...
  62. ncbi Low-dose cyclophosphamide and continuous-infusion interleukin-2 with famotidine in previously treated metastatic melanoma or kidney cancer
    Walter D Y Quan
    Division of Hematology Oncology, East Carolina University Brody School of Medicine, Greenville, NC 27858, USA
    Cancer Biother Radiopharm 23:108-13. 2008
    ..b>Famotidine may increase IL-2 internalization by the IL-2 receptor on T-lymphocytes...
  63. ncbi Usefulness of famotidine in functional dyspepsia patient treatment: comparison among prokinetic, acid suppression and antianxiety therapies
    H Seno
    Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Aliment Pharmacol Ther 21:32-6. 2005
    ..The treatment of functional dyspepsia is controversial...
  64. ncbi [Preparation of famotidine microemulsion and its quality evaluation]
    Hai ying Ye
    Department of Pharmacy, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China
    Di Yi Jun Yi Da Xue Xue Bao 23:68-70. 2003
    To study the preparation of famotidine microemulsion (FM) and its quality evaluation, thereby to establish the quality-control criteria for this preparation.
  65. ncbi Effects of omeprazole and famotidine on fibroblast growth factor-2 during artificial gastric ulcer healing in humans
    Motohiro Esaki
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Eur J Gastroenterol Hepatol 14:365-9. 2002
    ..This study aimed to compare the effects of omeprazole and famotidine on ulcer healing and fibroblast growth factor-2 levels in gastric ulcers induced by endoscopic mucosal resection.
  66. ncbi Formulation and evaluation of famotidine floating tablets
    M Jaimini
    Bhupal Nobles College of Pharmacy, Udaipur 313001, Rajasthan, India
    Curr Drug Deliv 4:51-5. 2007
    The purpose of this investigation was to prepare a gastroretentive drug delivery system of famotidine. Floating tablets of famotidine were prepared employing two different grades of methocel K100 and methocel K15M by effervescent ..
  67. ncbi Evaluation of carboxymethyl-beta-cyclodextrin with acid function: improvement of chemical stability, oral bioavailability and bitter taste of famotidine
    Fatma M Mady
    Department of Pharmaceutics, Faculty of Pharmacy, El Minia University, El Minia Governate 61732, Egypt
    Int J Pharm 397:1-8. 2010
    ..CM-beta-CyD) on the aqueous solubility, chemical stability and oral bioavailability of famotidine (FMT) as well as on its bitter taste...
  68. ncbi The quantitative prediction of bitterness-suppressing effect of sweeteners on the bitterness of famotidine by sweetness-responsive sensor
    Yoshimi Hashimoto
    Astellas Pharma Inc, Information System Management Department, 3 17 1 Hasune, Tokyo 174 8612, Japan
    Chem Pharm Bull (Tokyo) 55:739-46. 2007
    ..prediction of the bitterness-suppressing effect of sweeteners (sucrose or sugar alcohols) on the bitterness of famotidine (or quinine sulfate as control) solutions using an artificial taste sensor...
  69. ncbi A prospective randomized trial of either famotidine or omeprazole for the prevention of bleeding after endoscopic mucosal resection and the healing of endoscopic mucosal resection-induced ulceration
    Y Yamaguchi
    The Third Department of Internal Medicine, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
    Aliment Pharmacol Ther 21:111-5. 2005
    ..However, uncertain whether an histamine2-receptor antagonist or proton-pump inhibitor is more effective...
  70. ncbi Initial 48-hour acid inhibition by intravenous infusion of omeprazole, famotidine, or both in relation to cytochrome P450 2C19 genotype status
    Mitsushige Sugimoto
    First Department of Medicine and Center for Clinical Research, Hamamatsu University School of Medicine, Shizuoka, Japan
    Clin Pharmacol Ther 80:539-48. 2006
    ....
  71. ncbi Omeprazole may be superior to famotidine in the management of iatrogenic ulcer after endoscopic mucosal resection: a prospective randomized controlled trial
    B D Ye
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Chongno Gu, Seoul, Korea
    Aliment Pharmacol Ther 24:837-43. 2006
    ..However, the relative merits of proton pump inhibitor or histamine(2)-receptor antagonist for endoscopic mucosal resection-induced ulcers are not known...
  72. ncbi A new quadruple therapy for Helicobacter pylori using tripotassium dicitrato bismuthate, furazolidone, josamycin and famotidine
    W Z Liu
    Shanghai Institute of Digestive Disease, Renji Hospital, Shanghai Second Medical University, China
    Aliment Pharmacol Ther 14:1519-22. 2000
    ..In our previous study, a triple therapy using tripotassium dicitrato bismuthate (TDB), josamycin and furazolidone achieved a suboptimal cure rate of Helicobacter pylori infection...
  73. ncbi Preventive therapy for non-steroidal anti-inflammatory drug-induced ulcers in Japanese patients with rheumatoid arthritis: the current situation and a prospective controlled-study of the preventive effects of lansoprazole or famotidine
    K Miyake
    Third Department of Internal Medicine, Nippon Medical School, Sendagi, Tokyo, Japan
    Aliment Pharmacol Ther 21:67-72. 2005
    ..There is a lack of evidence for the efficacy of preventive medications for peptic ulcers (PUs) among long-term users of non-steroidal anti-inflammatory drugs (NSAIDs) in Japan...
  74. ncbi Relationship between histamine2-receptor antagonist medications and risk of invasive breast cancer
    Robert W Mathes
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 17:67-72. 2008
    ..The few previous studies evaluating this association have been null but have been limited by small sample sizes, and none have evaluated risk by either histologic type or estrogen receptor/progesterone receptor status...
  75. ncbi [Safety of proton pump inhibitors]
    Juan V Esplugues
    Departamento de Farmacologia, Facultat de Medicina i Odontologia, Universitat de Valencia, Valencia, Espana
    Med Clin (Barc) 127:790-5. 2006
    ..After two decades of use, PPIs have proved to be very effective and safe drugs...
  76. ncbi Effects of famotidine, mosapride and tandospirone for treatment of functional dyspepsia
    Y Kinoshita
    Department of Gastroenterology and Hepatology, Shimane University School of Medicine, Izumo shi, Shimane, Japan
    Aliment Pharmacol Ther 21:37-41. 2005
    ..An effective therapeutic strategy for functional dyspepsia (FD) has not been well-established...
  77. ncbi A new sensitive flow-injection chemiluminescence method for the determination of H(2)-receptor antagonists
    Yu Hai Tang
    Institute of Analytical Chemistry, Xi an Jiaotong University, Xi an 710061, People s Republic of China
    Luminescence 22:343-8. 2007
    ..of three kinds of H(2)-receptor antagonists: cimetidine (CIMT), ranitidine (RANT) hydrochloride and famotidine (FAMT). Under the optimum conditions, the linear range for the determination was 1.0 x 10(-9)-7...
  78. ncbi [Pharmacological efficacy of bismuth tripotassium dicitrate in peptic ulcer]
    Iu B Belousov
    Ter Arkh 79:58-66. 2007
  79. ncbi Spectrophotometric determination of H(2)-receptor antagonists via their oxidation with cerium(IV)
    Ibrahim A Darwish
    Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt
    Spectrochim Acta A Mol Biomol Spectrosc 69:33-40. 2008
    ..method has been developed and validated for determination of H(2)-receptor antagonists: cimetidine, famotidine, nizatidine and ranitidine hydrochloride...
  80. ncbi Carrier-mediated uptake of H2-receptor antagonists by the rat choroid plexus: involvement of rat organic anion transporter 3
    Yoshinori Nagata
    Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7 3 1, Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Drug Metab Dispos 32:1040-7. 2004
    ..anion transporter 3 (rOat3; Slc22a8) in the uptake of H(2)-receptor antagonists (cimetidine, ranitidine, and famotidine) by the isolated rat CP...
  81. ncbi Comparative study of the speed of acid-suppressing effects of oral administration of cimetidine and famotidine
    Kyoichi Adachi
    Department of Gastroenterology and Hepatology, Shimane University, School of Medicine, Shimane, Japan
    J Gastroenterol Hepatol 20:1012-5. 2005
    ..The aim of this study was to compare the rapidity of onset of antisecretory activity of cimetidine and famotidine when orally administered.
  82. ncbi Effects of histamine 2 receptor antagonists on endothelial-neutrophil adhesion and surface expression of endothelial adhesion molecules induced by high glucose levels
    Yoshiyuki Takeuchi
    Department of Internal Medicine and Bioregulation, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    J Diabetes Complications 21:50-5. 2007
    ..Of three histamine 2 receptor antagonists (cimetidine, ranitidine, and famotidine), only cimetidine significantly attenuated adhesion mediated by 48-h incubation with 27.8 mM glucose...
  83. ncbi Effect of Helicobacter pylori status on intragastric pH during administration of lafutidine or famotidine
    Tomoyuki Koike
    Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
    Hepatogastroenterology 54:1280-4. 2007
    ..The first aim of this study was to investigate the effect of H. pylori status on intragastric pH in healthy volunteers receiving lafutidine or famotidine. The second aim was to compare the effects of the two antisecretory drugs.
  84. ncbi [The effect of H2 receptor blockers on renal function. An attempt to accurately measure glomerular filtration]
    Waldemar Motyl
    Z Oddziału Wewnetrznego Szpitala Powiatowego w Drawsku Pomorskim, ul Bolesława Chrobrego 4, 78 500 Drawsko Pomorskie
    Ann Acad Med Stetin 50:97-105. 2004
    ..consisted of 76 healthy individuals randomly assigned to groups which were placed on cimetidine, ranitidine or famotidine. Creatinine clearance was measured in all participants...
  85. ncbi Gastroprotective and antioxidant effects of montelukast on indomethacin-induced gastric ulcer in rats
    Gunnur Ozbakis Dengiz
    Department of Pharmacology, Faculty of Medicine, Karaelmas University, Turkey
    J Pharmacol Sci 105:94-102. 2007
    ..MPO), as markers of the ulceration process following oral administration of montelukast, lansoprazole, famotidine, and ranitidine, respectively, in rats with indomethacin-induced ulcers...
  86. ncbi Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats
    Naoaki Harada
    Department of Biodefense Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    Dig Dis Sci 52:469-77. 2007
    ..of calcitonin gene-related peptide (CGRP) and 6-keto-PGF(1alpha), a stable metabolite of prostacyclin, whereas famotidine, another H(2)-receptor antagonist, did not...
  87. ncbi In vitro availability of metformin in presence of h(2) receptor antagonists
    Najma Sultana
    Research Institute of Pharmaceutical Sciences, Faculty of Pharmacy, University of Karachi, Karachi 75270, Pakistan
    Pak J Pharm Sci 19:28-34. 2006
    ..2003 dissolution test apparatus. Commonly prescribed H(2) receptor antagonists like cimetidine, ranitidine and famotidine were used in these studies...
  88. ncbi [UV spectrophotometric assay of famotidine in combination with picrolonic acid, picrolinate]
    M Apostu
    Universitatea de Medicină si Farmacie Gr T Popa Iaşi, Facultatea de Farmacie, Disciplina de Chimie Analitică
    Rev Med Chir Soc Med Nat Iasi 109:422-5. 2005
    b>Famotidine, belonging to H2-antagonist group, is a compound containing a thiazolic moiety and it is used in peptic ulcer therapy...
  89. ncbi Effects of rabeprazole or famotidine during cardiac surgery on perioperative gastric and esophageal pH readings
    Shigeyoshi Gon
    Department of Cardiovascular Surgery, Dokkyo Medical University Koshigaya Hospital, Koshigaya, Saitama, Japan
    Jpn J Thorac Cardiovasc Surg 54:278-84. 2006
    ..Upper gastrointestinal bleeding, particularly from a stress-induced duodenal ulcer, is an extremely important perioperative complication in cardiovascular surgery...
  90. ncbi In vitro availability studies of enoxacin in presence of H2 receptor antagonists
    M Saeed Arayne
    Department of Chemistry, University of Karachi Karachi 75270, Pakistan
    Pak J Pharm Sci 20:235-43. 2007
    ..In present study in vitro release of enoxacin in presence of cimetidine, ranitidine and famotidine has been studied on a B.P...
  91. ncbi Effects of ranitidine on quality of gastric ulcer healing compared with famotidine: a randomized, controlled, multicenter trial
    K Higuchi
    Department of Gastroenterology, Graduate School of Medicine, Osaka City University, Abeno Ku, Japan
    Int J Clin Pharmacol Res 25:187-94. 2005
    ..The aim of this study was to investigate the effects of ranitidine compared with those of famotidine on the quality of gastric ulcer healing...
  92. ncbi Fosinopril H(2)-receptor antagonists interaction studies by derivative spectroscopy
    Najma Sultana
    Research Institute of Pharmaceutical Sciences, University of Karachi, Karachi 75270, Pakistan
    Pak J Pharm Sci 20:19-25. 2007
    ..Commonly prescribed H(2) receptor antagonists like cimetidine, ranitidine and famotidine were used in these studies...
  93. ncbi [Concomitant dosing of a H2 receptor antagonist (H2RA) with a triple therapy increases the cure rate of Helicobacter pylori infection]
    Keisuke Okudaira
    Second Department of Internal Medicine, National Defense Medical College
    Nihon Rinsho 63:391-6. 2005
  94. ncbi Four-day continuous gastric pH monitoring following anti-acid secretory drug administration: cross-over test to assess the early effects
    T Suzuki
    Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan
    Aliment Pharmacol Ther 27:66-71. 2008
    ..There have been few reports that compare the effect of histamine H2-receptor antagonists (H2RAs) and proton pump inhibitors (PPIs) using continuous gastric pH monitoring for a long duration...
  95. ncbi Simple and universal HPLC-UV method to determine cimetidine, ranitidine, famotidine and nizatidine in urine: application to the analysis of ranitidine and its metabolites in human volunteers
    Diane A I Ashiru
    Department of Pharmaceutics, The School of Pharmacy, University of London, 29 39 Brunswick Square, London WC1N 1AX, UK
    J Chromatogr B Analyt Technol Biomed Life Sci 860:235-40. 2007
    A validated, simple and universal HPLC-UV method for the determination of cimetidine, famotidine, nizatidine and ranitidine in human urine is presented...
  96. ncbi Continuous infusion interleukin-2 and antihistamines in metastatic kidney cancer
    Paul R Walker
    Division of Medical Oncology and Hematology, Medical University of Ohio at Toledo, Ruppert Center, 3120 Glendale Avenue, Toledo, OH 43614, USA
    Cancer Biother Radiopharm 20:487-90. 2005
    ..Studies in which cimetidine, ranitidine, or famotidine were regularly scheduled and administered concurrently with IL-2 were included. Thirteen studies were identified...
  97. ncbi The efficacy of preanesthetic proton pump inhibitor treatment for patients on long-term H2 antagonist therapy
    Kazuyoshi Hirota
    Department of Anesthesiology, University of Hirosaki School of Medicine, Hirosaki 036 8563, Japan
    Anesth Analg 101:1038-41, table of contents. 2005
    ..preanesthetic proton pump inhibitor (PPI; oral rabeprazol) use in patients receiving regular H2-antagonist (oral famotidine) therapy for more than 4 wk...
  98. ncbi Effect of long-term half-dose famotidine therapy on corpus gastritis in peptic ulcer disease
    T Kamada
    Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School, Matsushima, Kurashiki, Japan
    Aliment Pharmacol Ther 21:99-104. 2005
    ..Recent studies showed that acid-suppressive therapy aggravates corpus gastritis in patients with Helicobacter pylori infection...
  99. ncbi Evaluation of the effects of anti-secretory drugs on intragastric acidity: is combined therapy with a proton pump inhibitor and an H2 receptor antagonist effective as initial treatment?
    Masahiko Inamori
    J Gastroenterol 40:213-4. 2005
  100. ncbi Spermicidal efficacy of H2-receptor antagonists and potentiation with 2', 4'-dichlorobenzamil hydrochloride: role of intrasperm Ca2+
    A Gupta
    Department of Pharmaceutical Sciences and Drug Research, Punjabi University, 147 002, Patiala, India
    Contraception 68:61-4. 2003
    ..Influence of commonly used H(2)-receptor antagonists cimetidine, ranitidine and famotidine on sperm viability and intrasperm Ca(2+) was evaluated in ejaculated human semen samples...
  101. ncbi Measurement of meal-stimulated gastric acid secretion by in vivo gastric autotitration
    Jerry D Gardner
    Science for Organizations, Inc, Chatham, New Jersey 07928, USA
    J Appl Physiol (1985) 92:427-34. 2002
    ..Placebo, ranitidine (150 mg), ranitidine (75 mg), or famotidine (10 mg) was given 1 h after the beginning of the meal...

Research Grants9

  1. AGE-RELATED GASTRIC CHANGES AND DRUG ABSORPTION
    Aryeh Hurwitz; Fiscal Year: 1993
    ..in young adults with normal secretory status and after suppression of acid by the H2 receptor antagonist, famotidine. Gastric pH will be confirmed directly by concomitant ingestion of a radiotelemetry pH capsule...
  2. PREVENTION OF ULCER HEMORRHAGE BY H PYLORI ERADICATION
    Dennis Jensen; Fiscal Year: 2000
    ..be randomized to receive in a double-blind fashion either a full dose of a histamine-2-receptor antagonist (H2RA-Famotidine 40 mg HS) or placebo for the entire duration of the study. Patients whose H...
  3. Two Photon Microscope
    Marshall Montrose; Fiscal Year: 2005
    ..The application is supported by substantial interest, need, and financial support at the University, and will serve a strongly NIH-funded scientific community. ..
  4. SUBCELLULAR REGULATION OF COLONIC ION TRANSPORTERS
    Marshall Montrose; Fiscal Year: 2005
    ..abstract_text> ..
  5. Innovations in Gastrointestinal Research and Therapy: FASEB summer conference
    Marshall Montrose; Fiscal Year: 2005
    ..Our funding request is specifically to support this award program allowing more Junior Investigators to participate actively in the program. ..
  6. Arcturus Veritas Microdissection Microscope
    Marshall Montrose; Fiscal Year: 2006
    ..The application is supported by substantial interest, need, and financial support at the University, and will serve a strongly NIH-funded scientific community. [unreadable] [unreadable] [unreadable]..
  7. Gastrointestinal Response to Injury: Canada 2007
    Marshall Montrose; Fiscal Year: 2007
    ..The aim of this application is to obtain the funds for travel awards to facilitate the participation of young scientists in "Gastrointestinal Response to Injury: Canada 2007." [unreadable] [unreadable] [unreadable]..
  8. THE ROLE OF MYCOBACTERIA IN CROHN'S DISEASE
    David Graham; Fiscal Year: 2005
    ..The results of this study should either confirm or refute the proposed etiologic association of M. paratuberculosis and Crohn's disease as well as the identification of patients with Crohn's disease and M. paratuberculosis. ..
  9. Helicobacter pylori: Pathogenesis and Virulence
    Kenneth Simpson; Fiscal Year: 2005
    ....