acepromazine

Summary

Summary: A phenothiazine that is used in the treatment of PSYCHOSES.

Top Publications

  1. ncbi Evaluation of sedation on electroencephalographic spectral edge frequency 95 in dogs sedated by acupuncture at GV20 or Yintang and sedative combination
    Min Su Kim
    Biomedical Physics Laboratory, School of Physics, Seoul National University, Korea
    Acupunct Electrother Res 31:201-12. 2006
  2. ncbi Effects of medetomidine-midazolam, acepromazine-butorphanol, and midazolam-butorphanol on induction dose of thiopental and propofol and on cardiopulmonary changes in dogs
    Kentaro Kojima
    Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences The University of Tokyo, 1 1 1 Yayoi, Bunkyo ku, Tokyo 113 8657, Japan
    Am J Vet Res 63:1671-9. 2002
  3. ncbi Sedation with detomidine and acepromazine influences the endoscopic evaluation of laryngeal function in horses
    C Lindegaard
    University of Copenhagen, Faculty of Life Sciences, Department of Large Animal Sciences, Dyrlaegevej 48, DK 1870 Frederiksberg C, Denmark
    Equine Vet J 39:553-6. 2007
  4. ncbi Optimization of intraperitoneal injection anesthesia in mice: drugs, dosages, adverse effects, and anesthesia depth
    M Arras
    Institute of Laboratory Animal Science, Central Biological Laboratory, University of Zurich, Switzerland
    Comp Med 51:443-56. 2001
  5. ncbi Effects of midazolam-butorphanol, acepromazine-butorphanol and medetomidine on an induction dose of propofol and their compatibility in dogs
    Tadashi Sano
    The Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
    J Vet Med Sci 65:1141-3. 2003
  6. pmc Safety and efficacy of various combinations of injectable anesthetics in BALB/c mice
    Sandra Buitrago
    Department of Laboratory Animal Resources, Roswell Park Cancer Institute, Buffalo, NY, USA
    J Am Assoc Lab Anim Sci 47:11-7. 2008
  7. ncbi Effects of acepromazine on renal function in anesthetized dogs
    Ingrid Boström
    National Veterinary Institute, Department of Small Animals, SE 751 89 Uppsala, Sweden
    Am J Vet Res 64:590-8. 2003
  8. ncbi Comparison of sedative and analgesic/anesthetic effects induced by medetomidine, acepromazine, azaperone, droperidol and midazolam in laboratory pigs
    R Nishimura
    Department of Veterinary Surgery, Faculty of Agriculture, University of Tokyo, Japan
    J Vet Med Sci 55:687-90. 1993
  9. ncbi A comparison of acepromazine-buprenorphine and medetomidine-buprenorphine for preanesthetic medication of dogs
    Nicola J Grint
    Department of Veterinary Clinical Science, School of Veterinary Science, University of Liverpool, Leahurst, Neston, Wirral, CH46 7TE, England
    J Am Vet Med Assoc 237:1431-7. 2010
  10. ncbi Effects of acepromazine, butorphanol and buprenorphine on thermal and mechanical nociceptive thresholds in horses
    E J Love
    Department of Clinical Veterinary Science, University of Bristol, Langford House Taylor Monroe, Little Downham, Ely, Cambridgeshire, UK
    Equine Vet J 44:221-5. 2012

Research Grants

  1. Tumor NMR Images are Affected by Anesthetic
    Natarajan Raghunand; Fiscal Year: 2006
  2. Non-invasive assessment of murine intraocular pressure
    John Danias; Fiscal Year: 2003
  3. Arterial baroreceptor unloading causes hypertension
    TERRY THRASHER; Fiscal Year: 2005
  4. Pulmonary delivery of nicotine using the AERx System
    Stephen Farr; Fiscal Year: 2005
  5. LIFE AND DEATH OF RETINAL GANGLION CELLS
    Vittorio Porciatti; Fiscal Year: 2007
  6. Liposomal Opioids Extend Analgesia in Laboratory Animals
    Lisa Krugner Higby; Fiscal Year: 2008
  7. Complement activation in glaucoma
    John Danias; Fiscal Year: 2008

Detail Information

Publications195 found, 100 shown here

  1. ncbi Evaluation of sedation on electroencephalographic spectral edge frequency 95 in dogs sedated by acupuncture at GV20 or Yintang and sedative combination
    Min Su Kim
    Biomedical Physics Laboratory, School of Physics, Seoul National University, Korea
    Acupunct Electrother Res 31:201-12. 2006
    ..The acupoints used were the GV20 point and Yintang point. The sedatives used were acepromazine, butorphanol, diazepam, medetomidine, and phenobarbital, each using a different mechanism...
  2. ncbi Effects of medetomidine-midazolam, acepromazine-butorphanol, and midazolam-butorphanol on induction dose of thiopental and propofol and on cardiopulmonary changes in dogs
    Kentaro Kojima
    Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences The University of Tokyo, 1 1 1 Yayoi, Bunkyo ku, Tokyo 113 8657, Japan
    Am J Vet Res 63:1671-9. 2002
    To evaluate dose-sparing effects of medetomidine-midazolam (MM), acepromazine-butorphanol (AB), and midazolam-butorphanol (MB) on the induction dose of thiopental and propofol and to examine cardiopulmonary changes in dogs.
  3. ncbi Sedation with detomidine and acepromazine influences the endoscopic evaluation of laryngeal function in horses
    C Lindegaard
    University of Copenhagen, Faculty of Life Sciences, Department of Large Animal Sciences, Dyrlaegevej 48, DK 1870 Frederiksberg C, Denmark
    Equine Vet J 39:553-6. 2007
    ..On some occasions it is necessary to use sedation during the procedure and it is often speculated that the result of the examination might be influenced due to the muscle-relaxing properties of the most commonly used sedatives...
  4. ncbi Optimization of intraperitoneal injection anesthesia in mice: drugs, dosages, adverse effects, and anesthesia depth
    M Arras
    Institute of Laboratory Animal Science, Central Biological Laboratory, University of Zurich, Switzerland
    Comp Med 51:443-56. 2001
    ..g., embryo transfer/vasectomy) coupled with a simple method to assess anesthesia depth under routine laboratory conditions...
  5. ncbi Effects of midazolam-butorphanol, acepromazine-butorphanol and medetomidine on an induction dose of propofol and their compatibility in dogs
    Tadashi Sano
    The Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
    J Vet Med Sci 65:1141-3. 2003
    The effects of acepromazine-butorphanol (AB), midazolam-butorphanol (MB) and medetomidine (Med) on the induction dose of propofol and their compatibility with propofol were evaluated in client-owned dogs...
  6. pmc Safety and efficacy of various combinations of injectable anesthetics in BALB/c mice
    Sandra Buitrago
    Department of Laboratory Animal Resources, Roswell Park Cancer Institute, Buffalo, NY, USA
    J Am Assoc Lab Anim Sci 47:11-7. 2008
    Four combinations of drugs--ketamine-xylazine, ketamine-xylazine-acepromazine (KXA), ketamine-xylazine-buprenorphine, and ketamine-xylazine-carprofen--were compared for their ability to produce anesthesia in BALB/c mice...
  7. ncbi Effects of acepromazine on renal function in anesthetized dogs
    Ingrid Boström
    National Veterinary Institute, Department of Small Animals, SE 751 89 Uppsala, Sweden
    Am J Vet Res 64:590-8. 2003
    To investigate the effects of IM administration of acepromazine on indices of relative renal blood flow and glomerular filtration rate (GFR) by means of scintigraphy, as well as the effects on physiologic, hematologic, and serum ..
  8. ncbi Comparison of sedative and analgesic/anesthetic effects induced by medetomidine, acepromazine, azaperone, droperidol and midazolam in laboratory pigs
    R Nishimura
    Department of Veterinary Surgery, Faculty of Agriculture, University of Tokyo, Japan
    J Vet Med Sci 55:687-90. 1993
    The sedative and analgesic/anesthetic effects of medetomidine, acepromazine, azaperone, droperidol and midazolam were compared in laboratory pigs...
  9. ncbi A comparison of acepromazine-buprenorphine and medetomidine-buprenorphine for preanesthetic medication of dogs
    Nicola J Grint
    Department of Veterinary Clinical Science, School of Veterinary Science, University of Liverpool, Leahurst, Neston, Wirral, CH46 7TE, England
    J Am Vet Med Assoc 237:1431-7. 2010
    To assess sedative and cardiopulmonary effects of premedication with a medetomidine-buprenorphine or acepromazine-buprenorphine combination in dogs anesthetized with propofol and isoflurane.
  10. ncbi Effects of acepromazine, butorphanol and buprenorphine on thermal and mechanical nociceptive thresholds in horses
    E J Love
    Department of Clinical Veterinary Science, University of Bristol, Langford House Taylor Monroe, Little Downham, Ely, Cambridgeshire, UK
    Equine Vet J 44:221-5. 2012
    To investigate the antinociceptive effects of buprenorphine administered in combination with acepromazine in horses and to establish an effective dose for use in a clinical environment.
  11. ncbi Effect of acepromazine, butorphanol, or N-butylscopolammonium bromide on visceral and somatic nociception and duodenal motility in conscious horses
    L Chris Sanchez
    Island Whirl Equine Colic Research Laboratory, Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    Am J Vet Res 69:579-85. 2008
    To evaluate effects of butorphanol, acepromazine, and N-butylscopolammonium bromide (NBB) on visceral and somatic nociception and duodenal motility in conscious, healthy horses.
  12. pmc Effects of acepromazine on the stress response in Southern chamois (Rupicapra pyrenaica) captured by means of drive-nets
    Jorge R Lopez-Olvera
    Servei d Ecopatologia de Fauna Salvatge, Facultat de Veterinària Edifici V, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Can J Vet Res 71:41-51. 2007
    ..stress response of Southern chamois (Rupicapra pyrenaica) to capture and physical restraint and the effects of acepromazine (a short-acting neuroleptic) on this response...
  13. ncbi Effects of acepromazine on the incidence of vomiting associated with opioid administration in dogs
    Alexander Valverde
    Department of Large Animal Clinical Sciences, University of Florida, Gainesville, FL 32610, USA
    Vet Anaesth Analg 31:40-5. 2004
    To evaluate the anti-emetic properties of acepromazine in dogs receiving opioids as pre-anesthetic medication.
  14. ncbi A retrospective study on the use of acepromazine maleate in dogs with seizures
    Karen M Tobias
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee 37996 4544, USA
    J Am Anim Hosp Assoc 42:283-9. 2006
    Use of acepromazine (i.e., acetylpromazine) maleate in dogs with a history of seizures is reportedly contraindicated because of the risk of decreasing the seizure threshold in these animals...
  15. ncbi Determination of acepromazine, ketamine, medetomidine, and xylazine in serum: multi-residue screening by liquid chromatography-mass spectrometry
    Irina R Miksa
    University of Pennsylvania, School of Veterinary Medicine, Department of Pathobiology, New Bolton Center, Toxicology, Pennsylvania 19348, USA
    J Anal Toxicol 29:544-51. 2005
    ..detection and quantitation method for four chemically different drugs: medetomidine, xylazine, ketamine, and acepromazine. Chromatographic separation was carried out on a liquid chromatography-mass spectrometry instrument with a C18-..
  16. ncbi Reduced resident time and pharmacodynamic effects of acepromazine after subclinical multiple dosage in exercised thoroughbreds
    C C Chou
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, The University of Florida, Gainesville, FL, USA
    J Vet Pharmacol Ther 25:379-82. 2002
  17. ncbi Antinociceptive effects of tramadol and acepromazine in cats
    Paulo V M Steagall
    Faculty of Veterinary Medicine and Animal Science, FMVZ, UNESP, Botucatu, SP, Brazil
    J Feline Med Surg 10:24-31. 2008
    Effects of tramadol and acepromazine on pressure and thermal thresholds were examined in eight cats. After baseline measurements, subcutaneous (SC) tramadol 1 mg/kg, acepromazine 0.1 mg/kg, tramadol 1 mg/kg with acepromazine 0...
  18. ncbi Effects of acepromazine on pulmonary gas exchange and circulation during sedation and dissociative anaesthesia in horses
    Stina Marntell
    Department of Large Animal Clinical Sciences, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Vet Anaesth Analg 32:83-93. 2005
    To study pulmonary gas exchange and cardiovascular responses to sedation achieved with romifidine and butorphanol (RB) alone, or combined with acepromazine, and during subsequent tiletamine-zolazepam anaesthesia in horses.
  19. ncbi The effects of detomidine, romifidine or acepromazine on echocardiographic measurements and cardiac function in normal horses
    Rikke Buhl
    Department of Large Animal Sciences, The Royal Veterinary and Agricultural University, Frederiksberg C, Denmark
    Vet Anaesth Analg 34:1-8. 2007
    To evaluate by echo- and electrocardiography the cardiac effects of sedation with detomidine hydrochloride, romifidine hydrochloride or acepromazine maleate in horses.
  20. ncbi Effects of preanesthetic administration of morphine on gastroesophageal reflux and regurgitation during anesthesia in dogs
    Deborah V Wilson
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48864, USA
    Am J Vet Res 66:386-90. 2005
    ..To determine the effect of morphine administered prior to anesthesia on the incidence of gastroesophageal reflux (GER) in dogs during the subsequent anesthetic episode...
  21. ncbi Pre-anesthetic meperidine: associated vomiting and gastroesophageal reflux during the subsequent anesthetic in dogs
    Deborah V Wilson
    Department of Large Animal Clinical Sciences, Michigan State University, East Lansing, MI 48864, USA
    Vet Anaesth Analg 34:15-22. 2007
    ..To determine the effect of meperidine administered prior to anesthesia on the incidence of vomiting before, and gastroesophageal reflux (GER) and regurgitation during, the subsequent period of anesthesia in dogs...
  22. ncbi The sedative and behavioral effects of nalbuphine in dogs
    Patrick A Lester
    Unit for Laboratory Animal Medicine, 018 Animal Research Facility, University of Michigan, 1301 E Catherine Street, Ann Arbor, MI 48109 0614, USA
    Contemp Top Lab Anim Sci 42:27-31. 2003
    ..sedation and frequency and intensity of adverse behaviors in dogs associated with nalbuphine when combined with acepromazine or xylazine compared with those of acepromazine or xylazine alone...
  23. ncbi Intra-vesicle administration of D-cloprostenol for induction of abortion in mid-gestation bitches
    R Manca
    Department of Animal Production, Faculty of Veterinary Medicine, University of Bari, Strada Provinciale per Casamassima Km 3, 70010 Bari, Italy
    Anim Reprod Sci 106:133-42. 2008
    ....
  24. ncbi Evaluation of the effects of the sedation with azaperone/acepromazine and immobilization with guaiphenesin/thiopentone in mules
    J U Carmona
    School of Veterinary Medicine, Universidad de Caldas, Air mail 275, Manizales, Caldas, Colombia
    Vet Res Commun 31:125-32. 2007
  25. ncbi Application of pulsed Doppler ultrasound for the evaluation of small intestinal motility in dogs
    Y J An
    Department of Radiology, College of Veterinary Medicine, Seoul National University, Seoul 151 742, Korea
    J Vet Sci 2:71-4. 2001
    ..01). However, in the dogs treated with ketamine HCl and acepromazine, the number of small intestinal peristalsis remained unchanged...
  26. ncbi Impact of sedation method on the diagnosis of hip and elbow dysplasia in Swedish dogs
    Sofia Malm
    Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, P O Box 7023, S 750 07 Uppsala, Sweden
    Prev Vet Med 78:196-209. 2007
    ..b>Acepromazine gave less than half the odds of hip dysplasia compared with medetomidine and butorphanol (the most common ..
  27. ncbi Effects of meloxicam on renal function in dogs with hypotension during anaesthesia
    Ingrid M Boström
    Department of Large Animal Clinical Sciences, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Vet Anaesth Analg 33:62-9. 2006
    To evaluate the effects of meloxicam on renal function in dogs anaesthetized and rendered hypotensive with acepromazine-thiopental-isoflurane.
  28. ncbi Effects of chronic baroreceptor unloading on blood pressure in the dog
    Terry N Thrasher
    Dept of Surgery, 10 South Pine St, Rm 400, Univ of Maryland, Baltimore, MD 21201, USA
    Am J Physiol Regul Integr Comp Physiol 288:R863-71. 2005
    ..However, because MAP did not fall to control levels, the results are compatible with the hypothesis that baroreceptor input can influence the long-term level of MAP...
  29. ncbi The stress caused by laparoscopy in sheep and its alleviation
    K J Stafford
    Institute of Veterinary Animal and Biomedical Sciences, Massey University, Private Bag 11222, Palmerston North, New Zealand
    N Z Vet J 54:109-13. 2006
    ..To determine the plasma cortisol response to laparoscopy in ewes and investigate means of reducing it...
  30. ncbi Relationships between a proprietary index, bispectral index, and hemodynamic variables as a means for evaluating depth of anesthesia in dogs anesthetized with sevoflurane
    María S Carrasco-Jiménez
    Department of Anesthesiology, Medical School, Hospital Universitario de Puerto Real, Cadiz University, Cadiz, Spain
    Am J Vet Res 65:1128-35. 2004
    ..To evaluate relationships among various techniques for monitoring anesthetic depth in sevoflurane-anesthetized dogs undergoing orthopedic surgery...
  31. ncbi Investigation of the effect of acepromazine on intravenous glucose tolerance tests in dogs
    Viorica Ionut
    Departments of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Am J Vet Res 65:1124-7. 2004
    To investigate the effects of administration of acepromazine on IV glucose tolerance tests (IVGTTs) in dogs.
  32. ncbi Intense (18)F-FDG uptake in brown fat can be reduced pharmacologically
    Mitsuaki Tatsumi
    Division of Nuclear Medicine, Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Nucl Med 45:1189-93. 2004
    ..In this study, we evaluated (18)F-FDG uptake in BAT of rats to determine whether pharmacologic or physiologic interventions affect the uptake, knowing that BAT has a high density of adrenergic innervation...
  33. ncbi Sonographic features of drug-induced splenic congestion
    Robert T O'Brien
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, 2015 Linden Drive, Madison, WI 53706, USA
    Vet Radiol Ultrasound 45:225-7. 2004
    ..to determine the maximum diameter in the minimum dimension prior to, and 15 min after, administration of acepromazine, thiopental, or propofol. Significant splenic enlargement was seen after administration of acepromazine (P<0...
  34. ncbi Risk factors for anaesthetic-related death in referred dogs
    D C Brodbelt
    Animal Health Trust, Lanwades Park, Kentford, Newmarket CB8 7UU
    Vet Rec 158:563-4. 2006
  35. ncbi Middle-latency auditory-evoked potential in acepromazine-sedated dogs
    Joanna C Murrell
    Department of Clinical Sciences of Companion Animals, Utrecht University, P O Box 80154, NL 3508 TD Utrecht, The Netherlands
    J Vet Intern Med 18:196-200. 2004
    ..The MLAEP was recorded in 12 dogs with and without sedation with acepromazine. Three needle electrodes were inserted SC. Click stimuli were delivered biaurally...
  36. ncbi Refractometry for quality control of anesthetic drug mixtures
    Jennifer M Stabenow
    Department of Comparative Medicine, Saint Louis University School of Medicine, St Louis, Missouri, USA
    J Am Assoc Lab Anim Sci 45:60-3. 2006
    ..Dilutions of ketamine, xylazine, acepromazine, and buprenorphine were prepared with reagent-grade water to produce at least 4 concentration levels...
  37. ncbi Anesthesia case of the month. Hypotension
    Kristen G Hunyady
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
    J Am Vet Med Assoc 229:1250-3. 2006
  38. ncbi Results of 24-hour ambulatory electrocardiography in dogs undergoing ovariohysterectomy following premedication with medetomidine or acepromazine
    Misse A M Väisänen
    Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
    J Am Vet Med Assoc 226:738-45. 2005
    To investigate heart rate characteristics in dogs undergoing ovariohysterectomy following premedication with medetomidine or acepromazine.
  39. ncbi Mask induction of anaesthesia with isoflurane or sevoflurane in premedicated cats
    P Lerche
    Department of Veterinary Clinical Sciences, The Ohio State University, Columbus 43210, USA
    J Small Anim Pract 43:12-5. 2002
    ..Both sevoflurane and isoflurane produced mask induction of anaesthesia of a similar quality in this species. Sevoflurane provided more rapid induction of anaesthesia and establishment of a controlled airway than isoflurane...
  40. ncbi Effects of acetylpromazine or morphine on urine production in halothane-anesthetized dogs
    S A Robertson
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University East Lansing 48824-1314, USA
    Am J Vet Res 62:1922-7. 2001
    ..v. administration of fluids in the perioperative period, the type of preanesthetic agent used must be considered...
  41. ncbi Normal spatial memory following postseizure treatment with ketamine: selective damage attenuates memory deficits in brain-damaged rodents
    S A Santi
    Behavioral Neuroscience Laboratory, Laurentian University, Sudbury Ontario, Canada P3E 2C6
    Int J Neurosci 107:63-75. 2001
    ..min after the initiation of status epilepticus (SE) by lithium and pilocarpine, rats were injected with either acepromazine or ketamine...
  42. ncbi Effects of hydromorphone or oxymorphone, with or without acepromazine, on preanesthetic sedation, physiologic values, and histamine release in dogs
    L J Smith
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706, USA
    J Am Vet Med Assoc 218:1101-5. 2001
    OBJECTIVE: To compare hydromorphone with oxymorphone, with or without acepromazine, for preanesthetic sedation in dogs and assess changes in plasma concentration of histamine after drug administration. DESIGN: Randomized clinical study...
  43. ncbi Effect of acepromazine and butorphanol on isoflurane minimum alveolar concentration in goats
    T J Doherty
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, USA
    J Vet Pharmacol Ther 25:65-7. 2002
  44. ncbi Effects of carprofen on renal function and results of serum biochemical and hematologic analyses in anesthetized dogs that had low blood pressure during anesthesia
    Ingrid M Boström
    Department of Small Animals, National Veterinary Institute, Uppsala, Sweden
    Am J Vet Res 63:712-21. 2002
    ..effects of IV administered carprofen on indices of renal function and results of serum biochemical and hematologic analyses in dogs anesthetized with acepromazine-thiopentone-isoflurane that had low blood pressure during anesthesia.
  45. ncbi Evaluation of the perioperative stress response in dogs administered medetomidine or acepromazine as part of the preanesthetic medication
    Misse Väisänen
    Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Helsinki, Finland
    Am J Vet Res 63:969-75. 2002
    To compare the perioperative stress response in dogs administered medetomidine or acepromazine as part of the preanesthetic medication.
  46. ncbi Effects of acepromazine and butorphanol on tiletamine-zolazepam anesthesia in llamas
    Tulio M Prado
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996, USA
    Am J Vet Res 69:182-8. 2008
    To evaluate sedative, antinociceptive, and physiologic effects of acepromazine and butorphanol during tiletamine-zolazepam (TZ) anesthesia in llamas.
  47. pmc Physiology and behavior of dogs during air transport
    Renee Bergeron
    Departement des Sciences Animales, Universite Laval, Ste Foy, Quebec
    Can J Vet Res 66:211-6. 2002
    ..Each of 3 groups of 4 sedated (with 0.5 mg/kg body weight of acepromazine maleate) and 4 non-sedated (control) dogs was flown on a separate flight between Montreal, Quebec, and Toronto, ..
  48. pmc Stable in vivo imaging of densely populated glia, axons and blood vessels in the mouse spinal cord using two-photon microscopy
    Dimitrios Davalos
    Department of Pharmacology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    J Neurosci Methods 169:1-7. 2008
    ..This simplified technique can greatly expand the application of in vivo imaging to study spinal cord injury, regeneration, physiology and disease...
  49. ncbi A canine model used to simultaneously assess potential neurobehavioural and cardiovascular effects of candidate drugs
    Marcello Tontodonati
    Safety Pharmacology, Safety Assessment Department, GlaxoSmithKline R and D Centre, Via A Fleming 4, 37135 Verona, Italy
    J Pharmacol Toxicol Methods 56:265-75. 2007
    ....
  50. ncbi Comparisons of the effects of anesthesia and stress on release of tumor necrosis factor-alpha, leptin, and nitric oxide in adult male rats
    C A Mastronardi
    Pennington Biomedical Research Center, Louisiana State University, Baton Rouge 70808-4124, USA
    Exp Biol Med (Maywood) 226:296-300. 2001
    ..Adult male rats were anesthetized with ketamine/acepromazine/xylazine anesthesia (90 + 2 + 6 mg/ml, respectively) and an external jugular catheter was inserted for removal ..
  51. ncbi Effects of treatment with oxytocin, xylazine butorphanol, guaifenesin, acepromazine, and detomidine on esophageal manometric pressure in conscious horses
    Anne A Wooldridge
    Equine Health Studies Program, Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA
    Am J Vet Res 63:1738-44. 2002
    To compare effects of oxytocin, acepromazine maleate, xylazine hydrochloride-butorphanol tartrate, guaifenesin, and detomidine hydrochloride on esophageal manometric pressure in horses.
  52. ncbi Effects of acepromazine on the cardiovascular actions of dopamine in anesthetized dogs
    Eduardo R Monteiro
    Faculdade de Medicina Veterinaria, Centro Universitario de Maringa, Maringa, Parana, Brazil
    Vet Anaesth Analg 34:312-21. 2007
    To evaluate the effects of acepromazine maleate on the cardiovascular changes induced by dopamine in isoflurane-anesthetized dogs.
  53. ncbi The effects of xylazine, detomidine, acepromazine and butorphanol on equine solid phase gastric emptying rate
    D G M Sutton
    Institute of Comparative Medicine, University of Glasgow Veterinary School, UK
    Equine Vet J 34:486-92. 2002
    ..0 mg/kg i.v.), or detomidine (0.03 mg/kg i.v.) administration, or preceded by acepromazine (0.05 mg/kg i.m.) in randomised order...
  54. ncbi A protocol for managing urethral obstruction in male cats without urethral catheterization
    Edward S Cooper
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USA
    J Am Vet Med Assoc 237:1261-6. 2010
    ..To determine efficacy of a protocol for managing urethral obstruction (UO) in male cats without urethral catheterization...
  55. ncbi The effects of medetomidine on the action of vecuronium in dogs anaesthetized with halothane and nitrous oxide
    Asadollah Kariman
    Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
    Vet Anaesth Analg 35:400-8. 2008
    ..To quantify the effects of medetomidine on the onset and duration of vecuronium-induced neuromuscular blockade in dogs...
  56. ncbi Effects of doxapram HCl on laryngeal function of normal dogs and dogs with naturally occurring laryngeal paralysis
    Karen M Tobias
    Department of Small Animal Clinical Sciences, University of Tennessee, Knoxville, TN 37996 4544, USA
    Vet Anaesth Analg 31:258-63. 2004
    ..To compare the effects of IV doxapram on glottic size and arytenoid motion in normal dogs and in dogs with laryngeal paralysis...
  57. ncbi A comparison of subarachnoid buprenorphine or xylazine as an adjunct to lidocaine for analgesia in goats
    Francesco Staffieri
    Dipartimento dell Emergenza e dei Trapianti di Organi, Sezione di Chirurgia Veterinaria, Facolta di Medicina Veterinaria, Universita degli Studi di Bari, Valenzano Bari, Italy
    Vet Anaesth Analg 36:502-11. 2009
    ..To test the hypothesis that subarachnoid administration of buprenorphine and lidocaine provides more intense and longer lasting perioperative analgesia with less side effects than xylazine and lidocaine in goats...
  58. ncbi Total intravenous anesthesia with propofol and S(+)-ketamine in rabbits
    Fernando Sf Cruz
    Pharmacology Graduate Program, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil
    Vet Anaesth Analg 37:116-22. 2010
    ..To evaluate total intravenous anesthesia with propofol alone or in combination with S(+)-ketamine in rabbits undergoing surgery...
  59. ncbi Immobilization and intravenous anesthesia in a Sumatran rhinoceros (Dicerorhinus sumatrensis)
    Chris Walzer
    Research Institute of Wildlife Ecology, University of Veterinary Medicine, Savoyenstrasse 1, A 1160 Vienna, Austria
    J Zoo Wildl Med 41:115-20. 2010
    ..Subsequently, 0.74 mg (0.0014 mg/kg) etorphine and 3 mg (0.0057 mg/kg) acepromazine, with an additional 1.5 mg butorphanol (0.0028 mg/kg) and 1.5 mg (0...
  60. ncbi Effects of ovariohysterectomy on canine blood neutrophil respiratory burst: a chemiluminescence study
    Misse Väisänen
    Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
    Vet Surg 33:551-6. 2004
    ..To examine blood neutrophil counts and luminol-enhanced chemiluminescence (CL) responses in dogs undergoing ovariohysterectomy (OH), premedicated with 2 different drugs...
  61. ncbi Influence of isoflurane general anesthesia or anesthesia and surgery on thyroid function tests in dogs
    M A Wood
    Department of Small Animal Clinical Sciences, Virginia Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
    J Vet Intern Med 23:7-15. 2009
    ..Anesthesia and surgery affect thyroid function tests in humans but have not been studied in dogs...
  62. ncbi A comparison of extradural and intravenous methadone on intraoperative isoflurane and postoperative analgesia requirements in dogs
    Elisabeth N Leibetseder
    Clinic of Surgery and Ophthalmology, GE Gemeinsame Einrichtung of Anaesthesia and Intensive Care, University of Veterinary Medicine, Vienna, Austria
    Vet Anaesth Analg 33:128-36. 2006
    ..To compare the effects of intravenous (IV) and extradural (ED) methadone on end-tidal isoflurane concentration (Fe'ISO) and postoperative analgesic requirements in dogs undergoing femoro-tibial joint surgery...
  63. ncbi Glomerular filtration rate after tramadol, parecoxib and pindolol following anaesthesia and analgesia in comparison with morphine in dogs
    Kavitha Kongara
    Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand
    Vet Anaesth Analg 36:86-94. 2009
    ....
  64. ncbi Blood gas tensions, acid-base status and cardiovascular function in miniature swine anaesthetized with halothane and methoxyflurane or intravenous metomidate hydrochloride
    P Svendsen
    Biomedical Laboratory, University of Odense, Denmark
    Pharmacol Toxicol 64:88-93. 1989
    ..given atropine and anaesthetized with one of the following drug combinations: 1) azaperone + metomidate, 2) acepromazine + thiopentone for endotracheal intubation, followed by halothane + methoxyflurane in oxygen...
  65. ncbi The post-tetanic count during vecuronium-induced neuromuscular blockade in halothane-anaesthetized dogs
    Farshid Sarrafzadeh-Rezaei
    Department of Clinical Sciences, University of Urmia, Western Azerbaijan, Iran
    Vet Anaesth Analg 36:246-54. 2009
    ..facialis-m. nasolabialis (nF-mNL) and n. ulnaris-mm. carpi flexorii (nU-mCF) nerve-muscle units (NMUs) during profound vecuronium neuromuscular blockade in halothane-anaesthetized dogs...
  66. ncbi A clinical comparison of two anaesthetic protocols using lidocaine or medetomidine in horses
    Simone K Ringer
    Equine Hospital, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Vet Anaesth Analg 34:257-68. 2007
    ..To compare the effects of two balanced anaesthetic protocols on end-tidal isoflurane (Fe'ISO), cardiopulmonary performance and quality of recovery in horses...
  67. ncbi Evaluation of the analgesic effect of intracameral lidocaine hydrochloride injection on intraoperative and postoperative pain in healthy dogs undergoing phacoemulsification
    Shin Ae Park
    Department of Veterinary Surgery and Ophthalmology, Seoul National University, San 56 1, Sillim 9 Dong, Gwanak Gu, Seoul 151 742, Republic of Korea
    Am J Vet Res 71:216-22. 2010
    ..To evaluate the intraoperative and postoperative analgesic effects of intracameral lidocaine hydrochloride injection in dogs undergoing phacoemulsification...
  68. ncbi Post-anesthetic hyperthermia in cats
    Lysa P Posner
    Department of Clinical Sciences, VMC College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
    Vet Anaesth Analg 34:40-7. 2007
    ..To assess whether administration of hydromorphone and, or ketamine are associated with post-anesthetic hyperthermia in cats undergoing routine surgery...
  69. ncbi The effects of doxapram hydrochloride (dopram-V) on laryngeal function in healthy dogs
    Carrie Jean Miller
    Denver Veterinary Specialists, Wheat Ridge, CO 80033, USA
    J Vet Intern Med 16:524-8. 2002
    ..Thirty healthy dogs were studied. Dogs were premedicated with butorphanol tartrate (0.22 mg/kg IV), acepromazine maleate (0.05 mg/kg SC), and glycopyrrolate (0.005 mg/kg SC), followed by induction with propofol (4 mg/kg IV)...
  70. pmc Efficacy of preanesthetic intramuscular administration of ephedrine for prevention of anesthesia-induced hypotension in cats and dogs
    Christine Egger
    Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia 30601, USA
    Can Vet J 50:179-84. 2009
    ..of ephedrine would prevent anesthesia-induced hypotension in dogs and cats, 10 cats were anesthetized with acepromazine, butorphanol, ketamine, and isoflurane, and 8 dogs were anesthetized with acepromazine, morphine, propofol, and ..
  71. pmc Myogenic origin of the hypotension induced by rapid changes in posture in awake dogs following autonomic blockade
    Brett J Wong
    Integrative Physiology, 424 Field House, Iowa City, IA 52242, USA
    J Appl Physiol (1985) 105:1837-44. 2008
    ..The animals were sedated with acepromazine and lightly restrained in lateral recumbency on a tilt table...
  72. ncbi Bretylium and diltiazem in porcine cardiac procedures
    G P Rodgers
    Baylor College of Medicine, Houston, TX
    J Invest Surg 1:321-6. 1988
    ..General anesthesia was induced with a combination of ketamine HCl 25 mg/kg, atropine sulfate 0.1 mg/kg, and acepromazine 0.22 mg/kg, all given intramuscularly...
  73. ncbi Evaluation of intraperitoneal and incisional lidocaine or bupivacaine for analgesia following ovariohysterectomy in the dog
    Rachael E Carpenter
    Department of Large Animal Clinical Sciences, Michigan State University College of Veterinary Medicine, East Lansing, MI, USA
    Vet Anaesth Analg 31:46-52. 2004
    ..To determine if intraperitoneal (i.p.) and incisional (s.c.) lidocaine or bupivacaine provide analgesia following ovariohysterectomy (OHE)...
  74. ncbi A comparison of induction of anaesthesia using a target-controlled infusion device in dogs with propofol or a propofol and alfentanil admixture
    Adam Auckburally
    Division of Small Animal Clinical Studies, Institute of Comparative Medicine, University of Glasgow Veterinary School, Bearsden Road, Bearsden, Glasgow, UK
    Vet Anaesth Analg 35:319-25. 2008
    ..To compare induction targets, and the haemodynamic and respiratory effects, of propofol, or as an admixture with two different concentrations of alfentanil, delivered via a propofol target-controlled infusion (TCI) system...
  75. ncbi Investigation of the EEG effects of intravenous lidocaine during halothane anaesthesia in ponies
    Joanna C Murrell
    Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, University Utrecht, Utrecht, The Netherlands
    Vet Anaesth Analg 32:212-21. 2005
    ..The hypothesis tested was that in ponies, IV lidocaine is antinociceptive and would therefore obtund EEG changes during castration...
  76. ncbi Intraoperative determination of intestinal viability: a comparison with transserosal pulse oximetry and histopathological examination
    Mehmet Erikoglu
    Department of General Surgery, Selcuk University, Meram Medical Faculty, Konya, Turkey
    J Surg Res 128:66-9. 2005
    ..In this study, we aimed to measure the O2 saturation of ischemic intestinal segments and the relationship between these measures and concomitant pathological gradings...
  77. ncbi Speed of induction of anaesthesia in dogs administered halothane, isoflurane, sevoflurane or propofol in a clinical setting
    R G Pottie
    University Veterinary Centre, University of Sydney, Camden, NSW, Australia
    Aust Vet J 86:26-31. 2008
    ..To compare the speed and quality of induction of general anaesthesia using three different inhalant agents and one intravenous agent, in healthy dogs undergoing desexing surgery...
  78. pmc Effective and safe anesthesia for Yorkshire and Yucatan swine with and without cardiovascular injury and intervention
    Jan R Linkenhoker
    Division of Veterinary Resources, National Institutes of Health, Bethesda, Maryland, USA
    J Am Assoc Lab Anim Sci 49:344-51. 2010
    ..Phase 1 examined the safety and efficacy of acepromazine-ketamine, diazepam-ketamine, midazolam-ketamine, and medetomidine-ketamine in 5 healthy Yorkshire pigs...
  79. ncbi Castration of horses under total intravenous anaesthesia: analgesic effects of lidocaine
    Karine G Portier
    Universite de Lyon, Lyon, France
    Vet Anaesth Analg 36:173-9. 2009
    ..To evaluate the effects of local anaesthesia with lidocaine for castration of horses under intravenous anaesthesia...
  80. ncbi The effects of acute intraocular pressure elevation on rat retinal glutamate transport
    David J Holcombe
    School of Biomedical Sciences, University of Queensland, Brisbane, Queensland, Australia
    Acta Ophthalmol 86:408-14. 2008
    ..To investigate the relationship between intraocular pressure (IOP), retinal glutamate transport and retinal hypoxia during acute IOP elevations of varying magnitude...
  81. pmc The effect of body position, sedation, and thoracic bandaging on functional residual capacity in healthy deep-chested dogs
    Elizabeth A Rozanski
    Lung Function Testing Laboratory, Cummings School of Veterinary Medicine, Tufts University, 200 Westboro Road, North Grafton, Massachusetts 01536, USA
    Can J Vet Res 74:34-9. 2010
    ..in unsedated dogs and then again both standing and lateral following chest bandaging, and sedation with acepromazine, IV and butorphanol, IV...
  82. ncbi Electroacupuncture analgesia in dogs: is there a difference between uni- and bi-lateral stimulation?
    Renata N Cassu
    Department of Veterinary Surgery and Anaesthesiology, Faculty of Veterinary Medicine and Animal Science, FMVZ, UNESP, Botucatu, SP, Brazil
    Vet Anaesth Analg 35:52-61. 2008
    ..To compare the analgesic effect of uni- and bi-lateral electroacupuncture (EA) in response to thermal and mechanical nociceptive stimuli and to investigate the cardiorespiratory, endocrine, and behavioral changes in dogs submitted to EA...
  83. pmc Development of a technique for serial bilateral renal biopsy in steers
    O Alberto Chiesa
    Center for Veterinary Medicine, Office of Research, Division of Residue Chemistry, Food and Drug Administration, 8401 Muirkirk Road, Laurel, Maryland 20708, USA
    Can J Vet Res 70:87-93. 2006
    ..After feed was withheld for 24 h, laparoscopic surgery was performed in standing stocks. Acepromazine, xylazine, and butorphanol were used for sedation and analgesia, and 2% lidocaine was used for local anesthesia...
  84. ncbi Lipopolysaccharide-induced tumor necrosis factor-alpha release is controlled by the central nervous system
    C A Mastronardi
    Pennington Biomedical Research Center, Lousiana State University, Baton Rouge, LA 70808 4124, USA
    Neuroimmunomodulation 9:148-56. 2001
    ..would be either neurally or hormonally controlled, the effect on TNF-alpha release of anesthesia (ketamine/acepromazine/xylazine) and catecholaminergic agonists and antagonists, either alone or in the presence of LPS, was ..
  85. ncbi Evaluation of hemodynamic, metabolic, and electrolytic changes after graft reperfusion in a porcine model of intestinal transplantation
    R M de Oliveira Clark
    Department of Surgery, Botucatu School of Medicine UNESP, Sao Paulo State University, Botucatu SP, Brazil
    Transplant Proc 42:87-91. 2010
    ..We sought to establish an anesthetic protocol to evaluate the hemodynamic, metabolic, and electrolytic changes after graft reperfusion in pigs undergoing orthotopic intestinal transplant (ITx)...
  86. ncbi The cardiorespiratory effects of a fentanyl infusion following acepromazine and glycopyrrolate in dogs
    Suzanne Lemmens
    Division of Anesthesiology and Neurophysiology, Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
    Tijdschr Diergeneeskd 133:888-95. 2008
    ..Each session started with a non-medication period, followed by acepromazine with glycopyrrolate, followed by a loading dose and infusion of saline or fentanyl, and ended with the ..
  87. ncbi Hypotensive effect of push-pull gravitational stress occurs after autonomic blockade
    Don D Sheriff
    Department of Exercise Science, The University of Iowa, Iowa City, Iowa 52242, USA
    J Appl Physiol (1985) 95:167-71. 2003
    ..The animals were paced at 75 beats/min throughout the experiment. The animals were sedated with acepromazine and lightly restrained in lateral recumbency on a tilt table...
  88. ncbi Electrocardiography of Grevy's zebras (Equus grevyi)
    Debbie A Myers
    Louisiana State University, College of Veterinary Medicine, Veterinary Clinical Sciences, 1516 Skip Bertman Drive, Baton Rouge, Louisiana 70803, USA
    J Zoo Wildl Med 39:298-304. 2008
    ..ECG parameters for zebras anesthetized with a standardized dose of the drug combination etorphine-detomidine-acepromazine compared to those receiving additional supplements of these drugs and/or ketamine...
  89. ncbi Isoflurane is an effective alternative to ketamine/xylazine/acepromazine as an anesthetic agent for the mouse electroretinogram
    William R Woodward
    Department of Neurology, Oregon Health and Science University, Portland, USA
    Doc Ophthalmol 115:187-201. 2007
    ..Ketamine, in combination with xylazine and/or acepromazine, is the most commonly used anesthetic agent...
  90. ncbi Acute pulmonary edema after diazepam-ketamine in a dog
    Joseph Boutureira
    Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    Vet Anaesth Analg 34:371-6. 2007
    ..Moderate sedation was produced by premedication with glycopyrrolate, acepromazine, and hydromorphone, and anesthesia was induced by IV injection of diazepam and ketamine...
  91. ncbi Development of a mouse model to determine the systemic activity of potential flea-control compounds
    Karen A Santora
    Merck Research Labs, Merck and Co, Inc, P O Box 2000, Rahway, NJ 07065, USA
    Vet Parasitol 104:257-64. 2002
    ..Consequently, a protocol was developed which incorporated acepromazine maleate to temporarily sedate various strains of mice and allow fleas a window of time to feed undisturbed...
  92. pmc A comparison of the analgesic effects of butorphanol with those of meloxicam after elective ovariohysterectomy in dogs
    Nigel Caulkett
    Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4
    Can Vet J 44:565-70. 2003
    ..Fifteen dogs were premedicated with 0.05 mg/kg body weight (BW) of acepromazine by intramuscular (IM) injection, plus 0.2 mg/kg BW of meloxicam by subcutaneous (SC) injection...
  93. ncbi Comparison of two thiopental infusion rates for the induction of anaesthesia in dogs
    Alexandra H A Dugdale
    Department of Anaesthesia, University of Liverpool, Liverpool, UK
    Vet Anaesth Analg 32:360-6. 2005
    ..To compare the induction dose requirements of thiopental using two different infusion rates for induction of anaesthesia in dogs...
  94. ncbi Postoperative analgesic effects of epidural administration of neostigmine alone or in combination with morphine in ovariohysterectomized dogs
    Rodrigo L Marucio
    Department of Veterinary Surgery and Anesthesiology, Faculdade de Medicina Veterinaria e Zootecnia, Universidade Estadual Paulista, Botucatu, Sao Paulo, Brazil, 14870 000
    Am J Vet Res 69:854-60. 2008
    ..To evaluate analgesic effects of epidurally administered neostigmine alone or in combination with morphine in dogs after ovariohysterectomy. Animals-40 healthy bitches...
  95. ncbi Comparison of anesthetic induction in cats by use of isoflurane in an anesthetic chamber with a conventional vapor or liquid injection technique
    Renee D Schmid
    Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA
    J Am Vet Med Assoc 233:262-6. 2008
    ..To compare 2 techniques for induction of cats by use of isoflurane in an anesthetic chamber...
  96. ncbi Gamma scintigraphic evaluation of a miniaturized AERx pulmonary delivery system for aerosol delivery to anesthetized animals using a positive pressure ventilation system
    Deepa S Deshpande
    Aradigm Corporation, Hayward, CA 94545, USA
    J Aerosol Med 18:34-44. 2005
    ..The dogs were 3-4 years old, and weighed 10.4 kg and 13.6 kg. Acepromazine was used as pre-anesthetic medication. Anesthesia was induced with 5% isoflurane...
  97. ncbi Subcutaneous pre-anaesthetic medication with acepromazine-buprenorphine is effective as and less painful than the intramuscular route
    M Gurney
    Northwest Surgeons, Delamere House, Ashville Point, Cheshire
    J Small Anim Pract 50:474-7. 2009
    To compare reaction to injection, sedation and propofol induction dose in dogs receiving acepromazine-buprenorphine pre-anaesthetic medication by the intramuscular or subcutaneous routes.
  98. ncbi Effects of acepromazine maleate on platelet function assessed by use of adenosine diphosphate activated- and arachidonic acid- activated modified thromboelastography in healthy dogs
    Bobbi J Conner
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607
    Am J Vet Res 73:595-601. 2012
    To evaluate the effect of acepromazine maleate administered IV on platelet function assessed in healthy dogs by use of a modified thromboelastography assay.
  99. ncbi Comparison of tribromoethanol, ketamine/acetylpromazine, Telazol/xylazine, pentobarbital, and methoxyflurane anesthesia in HSD:ICR mice
    D J Gardner
    Division of Veterinary Services, Food and Drug Administration, Bethesda, MD 20892, USA
    Lab Anim Sci 45:199-204. 1995
    ..A direct correlation existed between duration of anesthesia and magnitude and duration of temperature reduction. Duration of anesthesia can be used to predict extent of hypothermia...
  100. ncbi Refinement of the dose of doxapram to counteract the sedative effects of acepromazine in dogs
    M Zapata
    Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA, USA
    J Small Anim Pract 54:405-8. 2013
    To evaluate the effectiveness of two doses of doxapram in reversing acepromazine sedation in dogs.
  101. ncbi Ultrasound-guided atlanto-occipital puncture for cerebrospinal fluid analysis on the standing horse
    M Depecker
    l Université, ONIRIS, Centre International de Santé du Cheval d ONIRIS CISCO, Atlanpole La Chantrerie, BP40706, Nantes F 44307, France
    Vet Rec 174:45. 2014
    ..Seven horses (six healthy and one mildly ataxic) were sedated with acepromazine (0.02 mg/kg bodyweight intravenously or 0.04 mg/kg bodyweight intramuscularly) and detomidine (0...

Research Grants7

  1. Tumor NMR Images are Affected by Anesthetic
    Natarajan Raghunand; Fiscal Year: 2006
    ..and resulting effects upon DCE-MRI images, using three commonly used anesthetic protocols: ketamine/xylazine/acepromazine, pentobarbital, and isoflurane, and one customized injectable anesthetic protocol: etomidate/fentanyl/midazolam...
  2. Non-invasive assessment of murine intraocular pressure
    John Danias; Fiscal Year: 2003
    ....
  3. Arterial baroreceptor unloading causes hypertension
    TERRY THRASHER; Fiscal Year: 2005
    ..These studies will provide a new framework for understanding the development and maintenance of hypertension. ..
  4. Pulmonary delivery of nicotine using the AERx System
    Stephen Farr; Fiscal Year: 2005
    ..The long-term goal of this proposed project is to develop an inhalation product (the AERx-nicotine) as a therapy for smoking cessation. ..
  5. LIFE AND DEATH OF RETINAL GANGLION CELLS
    Vittorio Porciatti; Fiscal Year: 2007
    ..Such outcomes are significant, since exploiting an animal model for testing neuroprotective strategies that preserve visual function is an important component of future research on treatments for glaucoma. ..
  6. Liposomal Opioids Extend Analgesia in Laboratory Animals
    Lisa Krugner Higby; Fiscal Year: 2008
    ..If proven efficacious, these analgesic regimens would lead to a significant change in the post-surgical care of animals used in biomedical research and veterinary medicine. ..
  7. Complement activation in glaucoma
    John Danias; Fiscal Year: 2008
    ..Findings from this work will have wider implications for other neurodegenerative disease. ..