Genomes and Genes
Summary: Sodium or sodium compounds used in foods or as a food. The most frequently used compounds are sodium chloride or sodium glutamate.
Publications245 found, 100 shown here
- Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research GroupF M Sacks
Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, USA
N Engl J Med 344:3-10. 2001..We studied the effect of different levels of dietary sodium, in conjunction with the Dietary Approaches to Stop Hypertension (DASH) diet, which is rich in vegetables, ..
- Activated vitamin D attenuates left ventricular abnormalities induced by dietary sodium in Dahl salt-sensitive animalsNatalya Bodyak
Cardiovascular Division and Division of Nephrology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Proc Natl Acad Sci U S A 104:16810-5. 2007..In summary, PC attenuates the development of LV alterations in DSS rats, and these effects should be examined in human clinical trials...
- Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trialEduardo Pimenta
Hypertension Unit, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane, QLD, Australia
Hypertension 54:475-81. 2009Observational studies indicate a significant relation between dietary sodium and level of blood pressure. However, the role of salt sensitivity in the development of resistant hypertension is unknown...
- Dietary sodium and the incidence of hypertension in the Chinese population: a review of nationwide surveysZhiquan Liu
Cardiovascular Division, Department of Internal Medicine, First Affiliated Hospital, Xi an Jiaotong University Medical School, Xi an, People s Republic of China
Am J Hypertens 22:929-33. 2009..High dietary salt consumption is considered a risk factor for hypertension...
- A review of methods to measure dietary sodium intakeBrooke Bentley
Student College of Nursing, University of Kentucky, Lexington, KY, USA
J Cardiovasc Nurs 21:63-7. 2006With the rising prevalence of heart failure, it is imperative to investigate reasons for dietary sodium nonadherence and to develop evidence-based interventions to promote adherence...
- Blood pressure response to changes in sodium and potassium intake: a metaregression analysis of randomised trialsJ M Geleijnse
Division of Human Nutrition and Epidemiology, Wageningen University, The Netherlands
J Hum Hypertens 17:471-80. 2003..51 vs -0.34 mmHg, P=0.074). In conclusion, reduced intake of sodium and increased intake of potassium could make an important contribution to the prevention of hypertension, especially in populations with elevated blood pressure...
- Dietary sodium: the dark horse amongst cardiovascular and renal risk factorsAlbert Mimran
Department of Internal Medicine, Hopital Lapeyronie, Montpellier Cedex, France
Nephrol Dial Transplant 23:2138-41. 2008
- Sodium in the Finnish diet: II trends in dietary sodium intake and comparison between intake and 24-h excretion of sodiumH Reinivuo
Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
Eur J Clin Nutr 60:1160-7. 2006To estimate cross-sectional and long-term dietary sodium intakes and sources in Finland, and to evaluate the validity of 48-h recall to assess sodium intake.
- ACE inhibition has adverse renal effects during dietary sodium restriction in proteinuric and healthy ratsI Hamming
Department of Pathology and Laboratory Medicine, University Medical Center Groningen and University of Groningen, The Netherlands
J Pathol 209:129-39. 2006..Further studies should elucidate the mechanisms underlying these observations and their impact on long-term renoprotection...
- Effect of renin-angiotensin-aldosterone system inhibition, dietary sodium restriction, and/or diuretics on urinary kidney injury molecule 1 excretion in nondiabetic proteinuric kidney disease: a post hoc analysis of a randomized controlled trialFemke Waanders
Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Am J Kidney Dis 53:16-25. 2009..We hypothesized that a decrease in proteinuria by using therapeutic interventions is associated with decreased urinary KIM-1 levels...
- A further subgroup analysis of the effects of the DASH diet and three dietary sodium levels on blood pressure: results of the DASH-Sodium TrialGeorge A Bray
Pennington Biomedical Research Center, Baton Rouge, Lousiana, USA
Am J Cardiol 94:222-7. 2004....
- Dietary sodium intake modulates myocardial relaxation responsiveness to angiotensin IIJonathan S Williams
Division of Endocrinology, Diabetes and Hypertension, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02115, USA
Transl Res 148:49-54. 2006b>Dietary sodium alters renovascular responsiveness to angiotensin II (Ang II) in normal subjects. Evidence supports a connection among dietary sodium, the rennin-angiotensin system, and myocardial function...
- The role of vasopressin in essential hypertension. Plasma levels and effects of the V1 receptor antagonist OPC-21268 during different dietary sodium intakesY Kawano
Division of Hypertension and Nephrology, National Cardiovascular Center, Osaka, Japan
Am J Hypertens 10:1240-4. 1997..Our results suggest that VP does not play an important role in mild essential hypertension through its action on the V1 receptors regardless of dietary sodium intake.
- Structural vascular changes in hypertension: role of angiotensin II, dietary sodium supplementation, and sympathetic stimulation, alone and in combination in ratsG Simon
Department of Medicine, VA Medical Center, Minneapolis, MN 55417, USA
Hypertension 37:255-60. 2001Elevated circulating angiotensin (Ang) II levels, dietary sodium, and sympathetic stimulation are recurrent themes of hypertension research, but their in vivo interaction in physiologically meaningful doses has not been adequately ..
- Knowledge, attitudes and behaviours related to dietary sodium among 35- to 50-year-old Ontario residentsSophia Papadakis
Minto Prevention and Rehabilitation Centre, University of Ottawa Heart Institute, Ottawa, Ontario
Can J Cardiol 26:e164-9. 2010Excessive consumption of dietary sodium is an important public health issue. Little is known about the knowledge, attitudes and behaviours related to sodium consumption among Canadians.
- Dietary sodium promotes increased water intake and urine volume in catsAmanda J Hawthorne
Waltham Centre for Pet Nutrition, Waltham on the Wolds, Leicestershire, UK
J Nutr 134:2128S-2129S. 2004
- High dietary sodium blunts affects of angiotensin-converting enzyme inhibition on vascular angiotensin I-to-angiotensin II conversion in ratsMenno J A Kocks
Department of Internal Medicine, Division of Nephrology, University of Groningen, The Netherlands
J Cardiovasc Pharmacol 42:601-6. 2003..To investigate whether high-dietary sodium-induced effects on vascular conversion of Ang I might be involved in the sodium-induced blunting of the ..
- Dietary sodium intake and its relation to human health: a summary of the evidenceAlexander G Logan
University of Toronto, Toronto, Canada
J Am Coll Nutr 25:165-9. 2006
- Long-term effects of dietary sodium intake on cytokines and neurohormonal activation in patients with recently compensated congestive heart failureGaspare Parrinello
Department of Internal Medicine, University of Palermo, Italy
J Card Fail 15:864-73. 2009..A growing body of evidence suggests that the fluid accumulation plays a key role in the pathophysiology of heart failure (HF) and that the inflammatory and neurohormonal activation contribute strongly to the progression of this disorder...
- Reducing dietary sodium intake: the Canadian contextSusan I Barr
Food, Nutrition, and Health, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
Appl Physiol Nutr Metab 35:1-8. 2010..men and two thirds of Canadian women have sodium intakes above the UL, Health Canada's Working Group on Dietary Sodium Reduction has been charged with developing, implementing, and overseeing a strategy to reduce Canadians' ..
- Clustering of endothelial markers of vascular damage in human salt-sensitive hypertension: influence of dietary sodium load and depletionC Ferri
University La Sapienza, Chair of I Clinica Medica, Andrea Cesalpino Foundation, Departments of Experimental Medicine, A s, University of L Aquila, L Aquila, Italy
Hypertension 32:862-8. 1998..Our findings support the hypothesis that salt sensitivity is correlated with an increased risk for developing hypertension-related cardiovascular damage...
- Modulation by dietary sodium intake of melanocortin 3 receptor mRNA and protein abundance in the rat kidneyXi Ping Ni
Division of Nephrology, San Francisco General Hospital, California, USA
Am J Physiol Regul Integr Comp Physiol 290:R560-7. 2006..001). No significant increase occurred in the cortex. The increase in MC3-R expression induced by dietary sodium was observed in inner medullary collecting duct (IMCD) cells isolated from the kidneys of HSD rats, suggesting ..
- Effect of dietary sodium chloride on gastro-oesophageal reflux: a randomized controlled trialMarissa C Aanen
Gastrointestinal Research Unit, University Medical Center, Utrecht, The Netherlands
Scand J Gastroenterol 41:1141-6. 2006..The objective of this study was to investigate the effect of increased dietary NaCl intake on gastro-oesophageal reflux and reflux mechanisms...
- The influence of dietary sodium on blood pressureNorman K Hollenberg
Department of Medicine, Brigham and Women s Hospital and Harvard Medical Center, Boston, MA 02115, USA
J Am Coll Nutr 25:240S-246S. 2006..On the bright side, prognosis is improved substantially by the array of antihypertensive drugs available today...
- Effects of dietary sodium and magnesium on cyclosporin A-induced hypertension and nephrotoxicity in spontaneously hypertensive ratsE M Mervaala
Institute of Biomedicine, Department of Pharmacology and Toxicology, University of Helsinki, Finland
Hypertension 29:822-7. 1997..In the present study, the effects of dietary sodium and magnesium on CsA toxicity were examined in spontaneously hypertensive rats...
- High dietary sodium intake increases white adipose tissue mass and plasma leptin in ratsMiriam H Fonseca-Alaniz
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, 1524 Prof Lineu Prestes Ave, 05508 900, Sao Paulo, SP, Brazil
Obesity (Silver Spring) 15:2200-8. 2007..Salt restriction has been reported to increase white adipose tissue (WAT) mass in rodents. The objective of this study was to investigate the effect of different sodium content diets on the lipogenic and lipolytic activities of WAT...
- Influence of an enriched dietary sodium chloride regime during gestation and suckling and post-natally on the ontogeny of hypertension in the ratN Hazon
Department of Zoology, University of Sheffield, UK
J Hypertens 6:517-24. 1988..abstract truncated at 250 words)..
- Dietary sodium effects on heart rate variability in salt sensitivity of blood pressureJessica D McNeely
Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
Psychophysiology 45:405-11. 2008High dietary sodium intake is a risk factor for hypertension, and heart rate variability (HRV) is decreased in hypertension. Effects of dietary sodium intake on HRV of normotensive persons have not, however, been investigated to date...
- Effects of aging and alterations in dietary sodium intake on total nitric oxide productionR J Schmidt
Departments of Medicine and Physiology, West Virginia University, Morgantown, WV 26506, USA
Am J Kidney Dis 37:900-8. 2001..Limitations of blood and urine measurements of NO(2) + NO(3) and cGMP as indices of NO activity are discussed...
- Dietary sodium deprivation evokes activation of brain regional neurons and down-regulation of angiotensin II type 1 receptor and angiotensin-convertion enzyme mRNA expressionB Lu
Department of Physiology and Pathophysiology, Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, School of Medicine, Xi an Jiaotong University, 76 W Yanta Road, Xi an, 710061, PR China
Neuroscience 164:1303-11. 2009..system (RAAS) is implicated in the induction of sodium appetite in rats and that different dietary sodium intakes influence the mRNA expression of central and peripheral RAAS components...
- Changes in urinary stone risk factors in hypocitraturic calcium oxalate stone formers treated with dietary sodium supplementationMarshall L Stoller
Department of Urology, School of Medicine, University of California San Francisco, San Francisco, California, USA
J Urol 181:1140-4. 2009We investigated the effects of supplemental dietary sodium on risk factors for urinary stone disease in stone forming patients with hypocitraturia.
- How far should salt intake be reduced?Feng J He
Blood Pressure Unit, St George s Hospital Medical School, Cranmer Terrace, London, England
Hypertension 42:1093-9. 2003..A further reduction to 3 g/d will have a much greater effect and should now become the long-term target for population salt intake worldwide...
- Estimate of the benefits of a population-based reduction in dietary sodium additives on hypertension and its related health care costs in CanadaMichel R Joffres
Simon Fraser University, Burnaby, British Columbia, Canada
Can J Cardiol 23:437-43. 2007..Reductions in dietary sodium additives significantly lower systolic and diastolic blood pressure, and population reductions in dietary ..
- Surface expression of sodium channels and transporters in rat kidney: effects of dietary sodiumGustavo Frindt
Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, NY 10065, USA
Am J Physiol Renal Physiol 297:F1249-55. 2009..We conclude that cleavage of gamma-ENaC and its expression at the apical surface play a major role in the regulation of renal Na reabsorption...
- The dietary sodium-blood pressure plot "stiffens"Alexei Y Bagrov
Hypertension 44:22-4. 2004
- Extrarenal ETB plays a significant role in controlling cardiovascular responses to high dietary sodium in ratsMamoru Ohkita
Department of Pediatrics, University of Michigan, Ann Arbor 48109 0656, USA
Hypertension 45:940-6. 2005..caused by an absence of renal ET(B) signaling and performed a series of experiments to examine the effect of dietary sodium (Na) on endothelin-1 (ET1) expression and renal function in wild-type (WT) and ET(B)-deficient rats...
- Urinary sodium excretion and cardiovascular mortality in Finland: a prospective studyJ Tuomilehto
Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
Lancet 357:848-51. 2001..We aimed to find out whether salt intake, measured by 24 h urinary sodium excretion, is an independent risk factor for cardiovascular disease frequency and mortality, and all-cause mortality...
- Heritability of blood pressure responses to dietary sodium and potassium intake in a Chinese populationDongfeng Gu
Cardiovascular Institute and Fu Wai Hospital, Beijing, China
Hypertension 50:116-22. 2007..We examined the heritability of blood pressure responses to dietary sodium and potassium intake in a family feeding study among 1906 study participants living in rural North China...
- Benefits of and barriers to dietary sodium adherenceJanet L Welch
Indiana University School of Nursing, Indianapolis, USA
West J Nurs Res 28:162-80; discussion 181-9. 2006Failure to limit dietary sodium leads to thirst, large fluid weight gain, and poor outcomes in patients receiving hemodialysis...
- Dietary sodium intake and subsequent risk of cardiovascular disease in overweight adultsJ He
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
JAMA 282:2027-34. 1999b>Dietary sodium is positively associated with blood pressure, and ecological and animal studies both have suggested that high dietary sodium intake increases stroke mortality.
- Effect of renin-angiotensin system activation by dietary sodium restriction and upright position on plasma leptin concentration in patients with essential hypertensionMarcin Adamczak
Department of Nephrology, Endocrinology and Metabolic Diseases, Silesian Medical University, Katowice, Poland
Med Sci Monit 8:CR473-7. 2002..This study was undertaken to assess the relationship between RAS and plasma leptin concentration in hypertensive patients under conditions of normal and restricted sodium supply and upright position...
- Dietary sodium as a risk factor for osteoporosis: where is the evidence?Birgit Teucher
Nutrition Division, Institute of Food Research, Norwich NR4 7UA, UK
Proc Nutr Soc 62:859-66. 2003..g. salt sensitivity). The reasons for inter-individual variability should be explored using post-genomic techniques...
- Sodium intake and risk of death from stroke in Japanese men and womenChisato Nagata
Department of Epidemiology and Preventive Medicine, Gifu University School of Medicine, 1 1 Yanagido, Gifu 501 1194, Japan
Stroke 35:1543-7. 2004..The purpose of this study was to examine the relation between sodium intake and death from stroke in a population-based cohort of Japanese men and women...
- Effect of dietary sodium intake on blood lipids: results from the DASH-sodium trialDavid W Harsha
Pennington Biomedical Research Center, Baton Rouge, LA, USA
Hypertension 43:393-8. 2004..There were no significant interactions between the effects of sodium and the DASH diet on serum lipids. In conclusion, changes in dietary sodium intake over the range of 50 to 150 mmol/d did not affect blood lipid concentrations.
- Long-term effects of weight loss and dietary sodium reduction on incidence of hypertensionJ He
Department of Epidemiology, the Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112 2699, USA
Hypertension 35:544-9. 2000To examine the long-term effects of weight loss and dietary sodium reduction on the incidence of hypertension, we studied 181 men and women who participated in the Trials of Hypertension Prevention, phase 1, in Baltimore, Md...
- Sodium intake and mortality follow-up in the Third National Health and Nutrition Examination Survey (NHANES III)Hillel W Cohen
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
J Gen Intern Med 23:1297-302. 2008..Sodium restriction is commonly recommended as a measure to lower blood pressure and thus reduce cardiovascular disease (CVD) and all-cause mortality. However, some studies have observed higher mortality associated with lower sodium intake...
- Reducing dietary sodium and decreases in cardiovascular disease in CanadaErika D Penz
Department of Medicine, University of Calgary, Calgary, Alberta
Can J Cardiol 24:497-1. 2008Increases in dietary sodium increase blood pressure, whereas emerging evidence confirms that the reduction in dietary sodium results in reduced cardiovascular events.
- Relations between dietary sodium and potassium intakes and mortality from cardiovascular disease: the Japan Collaborative Cohort Study for Evaluation of Cancer RisksMitsumasa Umesawa
Department of Public Health Medicine, Graduate School of Comprehensive Human Sciences, and the Institute of Community Medicine, University of Tsukuba, Tsukuba, Japan
Am J Clin Nutr 88:195-202. 2008..Limited evidence is available about the relations between sodium and potassium intakes and cardiovascular disease in the general population...
- Efficacy of nonpharmacologic interventions in adults with high-normal blood pressure: results from phase 1 of the Trials of Hypertension Prevention. Trials of Hypertension Prevention Collaborative Research GroupP K Whelton
Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University School of Hygiene and Public Health, Baltimore, USA
Am J Clin Nutr 65:652S-660S. 1997..These results suggest that both weight loss and sodium reduction provide an effective means to prevent hypertension. The long-term effects of both of these interventions are being tested in phase 2 of the trial...
- Increased dietary sodium alters Fos expression in the lamina terminalis during intravenous angiotensin II infusionSteven L Bealer
Department of Pharmacology and Toxicology, College of Pharmacy, 20 South 3000 East, Rm 201, University of Utah, Salt Lake City, UT 84121, USA
Exp Neurol 204:299-306. 2007These studies examined the effects of increased dietary sodium on expression of Fos, the protein product of c-fos, in forebrain structures in the rat following intravenous infusion with angiotensin II (AngII)...
- Effect of aerobic exercise training on blood pressure sensitivity to dietary sodium in older hypertensivesD R Dengel
School of Kinesiology, University of Minnesota, Minneapolis, 55455, USA
J Hum Hypertens 20:372-8. 2006..exercise training has been shown to lower blood pressure (BP) in older adults, its effect on BP sensitivity to dietary sodium (Na(+)) is unknown...
- Renal denervation chronically lowers arterial pressure independent of dietary sodium intake in normal ratsFrederic Jacob
Department of Physiology, Lillehei Heart Institute, University of Minnesota, Minneapolis 55455, USA
Am J Physiol Heart Circ Physiol 284:H2302-10. 2003..Overall, there were no between-group differences in sodium or water balance in either protocol. We conclude that renal nerves support basal levels of AP, irrespective of dietary sodium intake in normal rats.
- Dietary sodium intake and mortality: the National Health and Nutrition Examination Survey (NHANES I)M H Alderman
Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Lancet 351:781-5. 1998Population-wide restriction of dietary sodium has been recommended. However, little evidence directly links sodium intake to morbidity and mortality...
- Dietary sodium and target organ damage in essential hypertensionGuilhem du Cailar
Department of Internal Medicine and Hypertension, Hopital Lapeyronie, Montpellier, France
Am J Hypertens 15:222-9. 2002In addition to its widely contested influence on arterial pressure, dietary sodium may exert some nonpressure-related effects on left ventricular mass in humans...
- Changes in dietary sodium consumption modulate GLUT4 gene expression and early steps of insulin signalingMaristela Mitiko Okamoto
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, 1524 05508 900, Sao Paulo, Brazil
Am J Physiol Regul Integr Comp Physiol 286:R779-85. 2004..In the present study we investigated the influence of dietary sodium on 1) GLUT4 gene expression, by No the n and Western blotting analysis; 2) in vivo GLUT4 protein translocation,..
- Abnormal expression of ENaC and SGK1 mRNA induced by dietary sodium in Dahl salt-sensitively hypertensive ratsWataru Aoi
Department of Molecular Cell Physiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
Cell Biol Int 31:1288-91. 2007..the kidney of Dahl salt-sensitive (DS) rats was abnormally regulated by aldosterone, however it is unknown if dietary sodium affects the expression of ENaC and serum and glucocorticoid-regulated kinase 1 (SGK1), which plays an ..
- Randomized trials of sodium reduction: an overviewJ A Cutler
Division of Epidemiology and Clinical Applications, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA
Am J Clin Nutr 65:643S-651S. 1997..The blood pressure reduction that would result from a substantial lowering of dietary sodium in the US population could reduce cardiovascular morbidity and mortality.
- Dietary sodium intake regulates the ubiquitin-protein ligase nedd4-2 in the renal collecting systemDominique Loffing-Cueni
University of Fribourg, Department of Medicine Anatomy, Route Albert Gockel 1, CH 1700 Fribourg, Switzerland
J Am Soc Nephrol 17:1264-74. 2006..It is concluded that Nedd4-2 abundance is regulated by Na(+) diet, by a mechanism that likely involves aldosterone. This regulation may contribute to adaptation of apical ENaC activity to altered Na(+) intake...
- Evidence relating dietary sodium to cardiovascular diseaseMichael H Alderman
Albert Einstein College of Medicine, Dept of Epidemiology and Population Health, Bronx, New York 10461, USA
J Am Coll Nutr 25:256S-261S. 2006The expectation that dietary sodium intake might influence cardiovascular disease occurrence has been based upon its impact on blood pressure (BP)...
- Reducing the public health burden from elevated blood pressure levels in the United States by lowering intake of dietary sodiumStephen Havas
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, 21201, USA
Am J Public Health 94:19-22. 2004..Such a reduction would greatly enhance the chances of attaining the Healthy People 2010 objectives and would save at least 150 000 lives annually. This issue warrants public health intervention...
- The feasibility of implementing a dietary sodium reduction intervention among free-living normotensive individuals in south west NigeriaAdebowale A Adeyemo
College of Medicine, University of Ibadan, Nigeria
Ethn Dis 12:207-12. 2002..In this study, we tested the feasibility of achieving a reduction in dietary sodium intake in free-living individuals using a dietary intervention among 82 free-living normotensive adults in ..
- Influence of dietary sodium on the blood pressure and renal sympathetic nerve activity responses to intracerebroventricular angiotensin II and angiotensin III in anaesthetized ratsBelinda L Houghton
Department of Physiology, Windle Building, University College Cork, College Road, Cork, Republic of Ireland
Exp Physiol 95:282-95. 2010..c.v. AngII and AngIII; (2) highlight an important role for peripheral V(1) receptors during these responses; and (3) differentiate the effects of AngII and AngIII on blood pressure and RSNA...
- Presidential Address: 21st Scientific Meeting of the International Society of Hypertension: dietary sodium and cardiovascular disease: the 'J'-shaped relationMichael H Alderman
Albert Einstein College of Medicine, Department of Epidemiology and Population Health, 1300 Morris Park Avenue, Bronx, New York 10461, USA
J Hypertens 25:903-7. 2007
- Dietary sodium intake and asthma: an epidemiological and clinical reviewT D Mickleborough
Department of Kinesiology, Human Performance and Exercise Biochemistry Laboratory, Indiana University, Bloomington, Indiana 47401, USA
Int J Clin Pract 60:1616-24. 2006..factors that may have contributed to the rise in the prevalence of asthma over the past few decades, and dietary sodium has been considered to be a dietary constituent which may be implicated in this phenomenon...
- Role of dietary sodium in osteoporosisRobert P Heaney
Creighton University, Omaha, Nebraska 68178, USA
J Am Coll Nutr 25:271S-276S. 2006..Given the relative difficulty of the former, and the ancillary benefits of the latter, it would seem that the optimal strategy to protect the skeleton is to ensure adequate calcium and potassium intakes...
- Evidence-based politics of salt and blood pressureQais Al-Awqati
Kidney Int 69:1707-8. 2006
- Central angiotensin modulation of baroreflex control of renal sympathetic nerve activity in the rat: influence of dietary sodiumG F DiBona
Department of Internal Medicine, University of Iowa College of Medicine and Veterans Administration Medical Center, Iowa City, IA 52242, USA
Acta Physiol Scand 177:285-9. 2003..an intact blood-brain barrier to assess the role of endogenous angII of brain origin and (c) alterations in dietary sodium intake, a known physiological regulator of activity of the renin-angiotensin system (RAS), to assess the ..
- Sodium intake affects urinary albumin excretion especially in overweight subjectsJ C Verhave
Division of Nephrology, Department of Medicine, University Medical Center Groningen, Groningen University Institute of Drug Exploration GUIDE, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
J Intern Med 256:324-30. 2004..To examine the relationship between sodium intake and urinary albumin excretion, being an established risk marker for later cardiovascular morbidity and mortality...
- Dietary sodium restriction rapidly improves large elastic artery compliance in older adults with systolic hypertensionPhillip E Gates
Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
Hypertension 44:35-41. 2004We determined the temporal effects of dietary sodium restriction on large elastic artery compliance and systolic blood pressure (SBP) in 12 untreated, older (64+/-2 years) men and women (6 each) with stage 1 systolic hypertension...
- High-salt diet induces gastric epithelial hyperplasia and parietal cell loss, and enhances Helicobacter pylori colonization in C57BL/6 miceJ G Fox
Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge 02139, USA
Cancer Res 59:4823-8. 1999..pylori colonization. Furthermore, elevated salt intake may potentiate H. pylori-associated carcinogenesis by inducing proliferation, pit cell hyperplasia, and glandular atrophy...
- Effects of dietary sodium and genetic background on angiotensinogen and Renin in mousePierre Lantelme
Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City, USA
Hypertension 39:1007-14. 2002..The response of this tubular renin-angiotensin system to stepwise changes in dietary sodium was investigated in 2 mouse strains, the sodium-sensitive inbred C57BL/6 and the sodium-resistant CD1 outbred...
- Reducing the population burden of cardiovascular disease by reducing sodium intake: a report of the Council on Science and Public HealthBarry D Dickinson
American Medical Association, 515 N State St, Chicago, IL 60610, USA
Arch Intern Med 167:1460-8. 2007..In the continued absence of voluntary measures adopted by the food industry, new regulations will be required to achieve lower sodium concentrations in processed and prepared foods...
- Investigation of aldosterone-synthase inhibition in ratsJoël Ménard
INSERM U652, Paris, France
J Hypertens 24:1147-55. 2006..In-vivo investigation of aldosterone-synthase inhibitors requires experimental models to characterize the biological effects of these compounds...
- A missing link between a high salt intake and blood pressure increaseMakoto Katori
Department of Pharmacology, Kitasato University School of Medicine, Kanagawa, Japan
J Pharmacol Sci 100:370-90. 2006..Furthermore, pharmaceutical development of renal kallikrein releasers, such as K(ATP) channel blockers, and renal kininase inhibitors, such as ebelactone B, may lead to the development of novel antihypertensive drugs...
- The contribution of brain angiotensin II to the baroreflex regulation of renal sympathetic nerve activity in conscious normotensive and hypertensive ratsChunlong Huang
Department of Physiology, Aras Windle, University College Cork, Cork, Republic of Ireland
J Physiol 574:597-604. 2006..indicate that in the conscious state, the tonic inhibitory action of brain angiotensin II on the baroreflex regulation of renal sympathetic nerve activity was unaffected by raised dietary sodium, but its role was enhanced in the SHRSPs.
- Sodium and potassium excretion in normotensive and hypertensive population in KashmirR A Jan
Department of Medicine, Sher I Kashmir Institute of Medical Sciences, Srinagar
J Assoc Physicians India 54:22-6. 2006..20) in patients with hypertension. Thus sodium and potassium excretion, Na+-K+ molar ratio and body mass index has direct bearing in perpetuation or causation of hypertension in Kashmir which may be related to intake of salt tea...
- Hypertension, Na+/Ca2+ exchanger, and Na+, K+-ATPaseT Iwamoto
Department of Pharmacology, School of Medicine, Fukuoka University, Fukuoka, Japan
Kidney Int 69:2148-54. 2006..This proposed pathway may have enabled us to explain how to link dietary salt to hypertension...
- Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channelKiyoshi Nakagawa
Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232, USA
J Clin Invest 116:1696-702. 2006..It is expected that these results could lead to new strategies for the early diagnosis and clinical management of this devastating disease...
- Nonmodulating trait may precede the development of hypertensionM S Gordon
Endocrine-Hypertension Division, Brigham and Women's Hospital, Boston, Massachusetts 02115-5817
Am J Hypertens 7:789-93. 1994..We conclude that the nonmodulating trait may be a heritable defect that leads to the development of hypertension and is not an epiphenomenon...
- [Promoter variants of aldosterone synthase gene (CYP11B2) and salt-sensitivity of blood pressure]Agnieszka Wrona
Samodzielna Pracownia Patobiochemii i Biologii Molekularnej Pomorskiej AM w Szczecinie
Pol Arch Med Wewn 111:191-7. 2004..Our preliminary results suggest the lack of association of the T(-344)C CYP11B2 polymorphism with salt-sensitive hypertension as well as with activity of plasma renin-angiotensin-aldosterone system in Caucasian patients...
- Low-dose lithium combined with captopril prevents stroke and improves survival in salt-loaded, stroke-prone spontaneously hypertensive ratsJihong Xu
Institute of Pharmacology, University Hospital of Schleswig Holstein, Campus Kiel, Germany
J Hypertens 23:2277-85. 2005..In the present study, we investigated the effects of a low-dose combination treatment with lithium and captopril on survival and stroke prevention in salt-loaded, stroke-prone spontaneously hypertensive rats (SHRSP)...
- [Renin-angiotensin-aldosterone system and natriuretic peptide system--reference to cardiovascular diseases]Hirofumi Yasue
Kumamoto Aging Research Institute
Nihon Rinsho 62:164-9. 2004
- Plasma sodium: ignored and underestimatedFeng J He
Blood Pressure Unit, St George s Hospital Medical School, London, UK
Hypertension 45:98-102. 2005..Small changes in plasma sodium alter extracellular volume, which may influence blood pressure. Changes in plasma sodium may also affect blood pressure directly...
- Diet and blood pressure in South Africa: Intake of foods containing sodium, potassium, calcium, and magnesium in three ethnic groupsKaren E Charlton
Chronic Diseases of Lifestyle Unit, Medical Research Council, Tygerberg, South Africa
Nutrition 21:39-50. 2005....
- Salt and hypertension: a phylogenetic perspectiveArye Lev-Ran
Maccabi Health Services, Petah Tikva, Israel
Diabetes Metab Res Rev 21:118-31. 2005....
- Effects of changes in sodium balance on plasma and kidney angiotensin II levels in anesthetized and conscious Ren-2 transgenic ratsZuzana Husková
Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
J Hypertens 24:517-27. 2006....
- [Salt restriction in treatment of diabetes mellitus]Masahiro Motokawa
Department of Internal Medicine and Pathophysiology, Nagoya City University Graduate School of Medical Sciences
Nihon Rinsho 63:417-23. 2005
- G-protein beta-3 subunit gene C825 T polymorphism: influence on plasma sodium and potassium concentrations in essential hypertensive patientsDolores Nieto Martín
Unidad de Hipertensión Arterial y Lípidos, Servicio de Medicina Interna, Hospitales Universitarios Virgen del Rocio, Avenida Manuel Siurot s n, 41013 Sevilla, Spain
Life Sci 77:2879-86. 2005....
- Pulse-pressure-driven neutral lipid accumulation and correlative proinflammatory markers of accelerated atherogenesisCharles R Kiefer
Department of Hospital Laboratories, UMass Memorial Medical Center, One Biotech Park, Suite 200, 365 Plantation Street, Worcester, MA 01605 2376, USA
Atherosclerosis 183:17-24. 2005..weaning on a high-saturated fat, high-cholesterol diet until early adolescence (age 12 weeks), at which point dietary sodium was increased, and changes in blood pressure, serum analytes and histologic markers were tracked...
- The impact of daily sodium intake on posttransplant hypertension in kidney allograft recipientsK Keven
Ankara University School of Medicine, Department of Nephrology, Ankara, Turkey
Transplant Proc 38:1323-6. 2006..Although dietary sodium restriction is a widely recommended nonpharmacological measure for control of blood pressure (BP), no detailed ..
- Salt sensitivity: a consequence of the metabolic syndrome?Olle Melander
J Hypertens 24:1475-7. 2006
- Enhanced sodium sensitivity and disturbed circadian rhythm of blood pressure in essential hypertensionTakashi Uzu
Department of Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan
J Hypertens 24:1627-32. 2006....
- Long-term effect of nifedipine and hydrochlorothiazide on blood pressure and sodium homeostasis at varying levels of salt intake in mildly hypertensive patientsF C Luft
Department of Internal Medicine-Nephrology, , Germany
Am J Hypertens 4:752-60. 1991..The PRA appears inactivated, although not lowered. The effects of NIF on BP may be at least in part related to the natriuresis and blunting of PRA.(ABSTRACT TRUNCATED AT 250 WORDS)..
- Salt sensitivity of children with low birth weightGiacomo D Simonetti
Department of Nephrology, Inselspital, Bern University Hospital, University of Bern, Berne, Switzerland
Hypertension 52:625-30. 2008..Whether the changes in renal growth are causative or are the consequence of the same abnormal "fetal programming" awaits clarification...
- Renin and aldosterone are higher and the hyperinsulinemic effect of salt restriction greater in subjects with risk factors clusteringB M Egan
Department of Pharmacology, Medical University of South Carolina, Charleston 29425
Am J Hypertens 7:886-93. 1994..Plasma renin activity also tended to increase more on the low salt diet in the high risk group. Ambulatory blood pressures were greater on the low than the high salt diet only in the high risk group.(ABSTRACT TRUNCATED AT 250 WORDS)..
- Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humansNaomi D L Fisher
Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Circulation 117:3199-205. 2008..We predicted that blockade with the direct oral renin inhibitor aliskiren would produce renal vascular responses exceeding those induced by angiotensin-converting enzyme inhibitors and angiotensin receptor blockers...
- Salt-sensitive hypertension in ANP knockout mice: potential role of abnormal plasma renin activityL G Melo
Department of Physiology, University of Toronto, Ontario, Canada
Am J Physiol 274:R255-61. 1998....
- Prevention of salt-induced hypertension and fibrosis by AT1-receptor blockers in Dahl S ratsBinhui Liang
From the Hypertension Unit, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
J Cardiovasc Pharmacol 51:457-66. 2008..In Dahl S rats, AT1-receptor stimulation seems to play a critical role in salt-induced hypertension and fibrosis, but a lesser role in tissue hypertrophy...
- The in vivo effects of Tulbhagia violacea on blood pressure in a salt-sensitive rat modelIrene Mackraj
Pfizer Molecular Biology Research Facility, University of KwaZulu Natal, Durban 4000, South Africa
J Ethnopharmacol 117:263-9. 2008..The in vivo effects of Tulbhagia violacea on systemic arterial blood pressure and on the renin-angiotensin system in a Dahl salt-sensitive rat model were investigated...
- Congenic strains reveal the effect of the renin gene on skeletal muscle angiogenesis induced by electrical stimulationMicheline M de Resende
Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Physiol Genomics 33:33-40. 2008..The present study emphasizes the importance of maintaining normal renin regulation as well as ANG II levels during the angiogenesis process with a combination of physiological, genetic, and pharmacological manipulation of the RAS...
- Salt-sensitive blood pressure in mice with increased expression of aldosterone synthaseNatalia Makhanova
Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 701 Brinkhous Bullitt Building, Chapel Hill, NC 27599 7525, USA
Hypertension 51:134-40. 2008....
- Parathyroid Hormone & Vitamin D Effects on Salt Sensitivity and Vascular FunctionANNA LIZA BELEN VALINA TOTH; Fiscal Year: 2010..Americans enrolled in the NIH-funded ONOSS study to examine the following before and after a 6 week period of dietary sodium supplementation: Aim #1: determine blood pressure (BP)(cuff and ambulatory 24 hour), arterial stiffness (AS), ..
- Endogenous Aldosterone and Glucose HomeostasisJAMES MATTHEW LUTHER; Fiscal Year: 2013..We anticipate that targeted RAAS inhibition will minimize the adverse metabolic effects of dietary sodium restriction or diuretic administration, and improve glucose tolerance...
- Diet and pathophysiology of heart failure with preserved ejection fractionScott L Hummel; Fiscal Year: 2013..In 'salt-sensitive'animal models, high dietary sodium intake induces oxidative stress and inflammation in the heart, kidneys, and vasculature that cause HFpEF...
- Nutrition Intervention to Reduce Symptoms in Patients with Advanced Heart FailureTerry A Lennie; Fiscal Year: 2013..Therefore, the purposes of this study are to test the effects of a 6-month nutrition intervention o dietary sodium reduction combined with supplementation of lycopene and omega-3 fatty acids on heart failure symptoms, health-..
- Vascular Endothelial Dysfunction in Older Adults: Dietary Sodium RestrictionKristen Jablonski; Fiscal Year: 2010..Research Project: This project will determine the efficacy of dietary sodium restriction (DSR) to improve vascular endothelial function, a key expression of vascular aging, as assessed by ..
- Beta2-Adrenergic Receptor Gene Variation and Cardiovascular Control in HumansJohn H Eisenach; Fiscal Year: 2012..maneuvers like mental stress and handgrip, [unreadable]2-mediated cardiac and vascular function, and dietary sodium manipulation...
- Family-Based Genome-wide Association Study for Salt-Sensitivity of Blood PressureJiang He; Fiscal Year: 2011..to localize and identify genetic variants which determine an individual's blood pressure (BP) response to dietary sodium intake by conducting a two-stage genome-wide association (GWA) study using the data and DNA specimens ..
- Modifying Lifestyle in Prehypertensive Older Rural WomenCAROL HALL PULLEN; Fiscal Year: 2010..Approaches to Stop Hypertension (DASH) diet that is high in fruits, vegetables and low fat dairy products;dietary sodium reduction;regular endurance physical activity supplemented by resistance exercise;and weight reduction by ..
- Multigene Kinase Network, Kidney Transport and Salt in Essential HypertensionPaul A Welling; Fiscal Year: 2010..disorder of hypertension and hyperkalemia, to control kidney salt excretion and maintain blood pressure;2) Dietary sodium and potassium differently trigger signaling through the STK39/WNK pathway to regulate the activity of a key ..
- Vitamin D Deficiency Augments Renin-Angiotensin System Activity in ObesityAnand Vaidya; Fiscal Year: 2011..on the RAS, all subjects will be washed-out of any medications that interfere with the RAS, and maintained in dietary sodium, potassium, and calcium balance...
- GRK4 and development of salt sensitivityPedro A Jose; Fiscal Year: 2012..However, dietary sodium restriction may not be beneficial to all...
- Experience of Managing ESRD Dietary ModicationsMAYA NICOLE CLARK; Fiscal Year: 2011..Self-management of dietary sodium and fluid restriction are critical to ensuring positive health outcomes for ESRD patients requiring ..
- Discovery of Gene Variants and Mechanisms Underlying Salt-Sensitive HypertensionLaura A Cox; Fiscal Year: 2013..Major obstacles include difficulty controlling dietary sodium in human studies and availability of large, salt-na[unreadable]ve human populations to identify sodium-..
- Sodium Sensitivity and Risk of HypertensionJiang He; Fiscal Year: 2011..In addition, we will repeat the dietary sodium and potassium interventions as well as the cold pressor test in a random sub-sample of GenSalt study ..
- Aldosterone-independent regulation of ENaC by systemic saltOleh Pochynyuk; Fiscal Year: 2013..and inhibitory Bradykinin (BK) cascades is necessary for proper adaptation of ENaC activity to variations in dietary sodium. Our preliminary work strongly supports our central hypothesis that Ang II directly stimulates ENaC-mediated ..
- Coordination of Renal K and Na Transport by Vesicle TrafficJames B Wade; Fiscal Year: 2013..to either conserve sodium or excrete potassium, depending on whether aldosterone is induced by a change in dietary sodium or potassium...
- Effects of Dietary Sodium and Potassium Intake on Subclinical and Clinical CardioCheryl Anderson; Fiscal Year: 2012..The objectives of Dr. Anderson's research plan are to examine the main and interactive effects of dietary sodium and potassium intake (measured by 24-hour urinary excretion) on echocardiographic left ventricular (LV) mass ..
- Sodium and Cardiovascular Disease in Patients with Chronic Kidney DiseaseJiang He; Fiscal Year: 2010..The few prospective epidemiologic studies that examined the relationship between dietary sodium and potassium intake and risk of CVD provided contradictory findings...
- MINORITY SCHOOL FACULTY DEVELOPMENT AWARDHALCYON WATKINS; Fiscal Year: 1992..development of hypertension and urinary sodium excretion in genetic hypertensive rats on different levels of dietary sodium intake...
- REVERSAL OF MYOCARDIAL HYPERTROPHY IN HYPERTENSIONSubha Sen; Fiscal Year: 2002..Influential factors are dietary sodium, catecholamines, and many pharmacological agents used as antihypertensive drugs...
- gamma-MSH and Sodium MetabolismMichael Humphreys; Fiscal Year: 2007Variations in dietary sodium intake initiate integrated adjustments in neural and hormonal systems regulating sodium excretion by the kidneys in order to maintain overall sodium balance...
- EFFECT OF SODIUM ON BAROREFLEX FUNCTION IN MANMark Creager; Fiscal Year: 1991..II and vasopressin will be measured in 45 normotensive and 45 hypertensive subjects during low and high dietary sodium intake...
- A Family Partnership Intervention for Heart FailureSandra Dunbar; Fiscal Year: 2009..Patient variables and measures are dietary sodium (24-hour urinary sodium), medication adherence to HF drugs including angiotensin converting enzyme inhibitors ..
- SODIUM-POTASSIUM BLOOD PRESSURE TRIAL IN CHILDRENAlan Sinaiko; Fiscal Year: 1991..This project will test the hypothesis that a reduction of dietary sodium and/or an increase in the potassium-sodium ratio will decrease the rate of rise in blood pressure during ..
- Etiology of Age-Related Defects in Urine ConcentrationYing Tian; Fiscal Year: 2001..water (dehydration, Aim 1); 2) increased extracellular fluid water (water loading, Aim 2); and 3) altered dietary sodium intake (low, normal, and high NaCl diet, Aim 3)...
- 24,25-DIHYDROXYVITAMIN D: MARKER OF SALT SENSITIVITYConnie Weaver; Fiscal Year: 2001..The primary aim of this proposal is to test the hypothesis that high dietary sodium increases the calcium intakes required for optimal calcium retention in both black and white adolescent girls...
- NEURAL CONTROL OF FLUID HOMEOSTASIS IN HYPERTENSIONGregory Fink; Fiscal Year: 2001..This is particularly the case where dietary sodium chloride (salt) intake is high...
- HUMORAL MECHANISMS IN CARDIAC HYPERTROPHYShirley Smith; Fiscal Year: 1991..b>Dietary sodium has been shown to affect the concentration of AII and the atrial granules which contain a natriuretic hormone...
- NEUROHUMORAL CONTROL OF BLOOD VOLUMEThomas Peterson; Fiscal Year: 1992..of the renal nerves and/or increases in ANF for eliciting the renal excretory responses to chronic changes in dietary sodium intake, (4) to determine if the level of sodium intake affects the magnitude of and renal nerve and ANF ..
- CHRONIC STRESS & SODIUM EFFECTS ON HYPERTENSIONJAYLAN TURKKAN; Fiscal Year: 1991..and after six months of exposure to daily behavioral stress sessions combined with daily ingestion of excess dietary sodium. Controls will receive stress only...
- STRESS, SODIUM, AND BLOOD PRESSURE REGULATIONThomas Pickering; Fiscal Year: 1990..Half of the subjects in each group will be randomized to take slow release sodium capsules to increase their dietary sodium by 100 meq/day, and the other half matching placebo...
- RENAL HEMODYNAMIC ABNORMALITIES IN EARLY DIABETESNORMAN BANK; Fiscal Year: 1991..Long-term studies will be carried out to determine whether dietary sodium restriction prevents renal pathologic changes of diabetes and proteinuria...
- Tissue Kallikrein, Oxidative Stress and Renal FibrosisJulie Chao; Fiscal Year: 2007..salt-induced hypertension and end-stage renal failure, as well as with blood pressure responses to changes in dietary sodium restriction...
- ABNORMAL PRESSURE NATRIURESIS IN HYPERTENSIONJoey Granger; Fiscal Year: 2009..renal medullary endothelin system plays a greater role in regulating sodium excretion and blood pressure as dietary sodium intake is increased 2) To test the hypothesis that the reduction in sodium excretion and elevation in arterial ..
- Gene-Environment Interactions and Stroke SusceptibilityMyriam Fornage; Fiscal Year: 2004..The role of dietary sodium and potassium in modulating the onset of stroke has been well documented both in humans and animal models...
- DIETARY SODIUM RESTRICTION IN GENERAL MEDICALMyron Weinberger; Fiscal Year: 1991..b>Dietary sodium restriction has been advocated for the primary or adjunctive treatment of essential hypertension but practical ..
- SODIUM, HYPERTENSION, AND RENAL A2-RECEPTORSWILLIAM PETTINGER; Fiscal Year: 1992b>Dietary sodium intake can have a profound influence on blood pressure of hypertensive patients...
- INSULIN ACTION, SODIUM AND EXERCISE IN HYPERTENSIONDonald Dengel; Fiscal Year: 1999..These metabolic changes may raise BP in the elderly by increasing sensitivity to dietary sodium and causing sodium and water retention to reduce renal plasma flow (RPF) and increase glomerular filtration ..
- SODIUM & NEUROPEPTIDES IN STRESS INDUCED HYPERTENSIONJULIANNA SZILAGYI; Fiscal Year: 1991..three models of stress (territorial stress, rotation stress and isolation stress) while being exposed to three dietary sodium regimes (low, normal, high sodium)...
- STRESS, SODIUM, AND BLOOD PRESSURE REGULATIONGERALD DIBONA; Fiscal Year: 1991..is designed to determine the physiological and pathophysiological factors involved in the interaction between dietary sodium intake and environmental stress in relation to the pathogenesis of hypertension...
- DIETARY CONTROL AND PREVENTION OF HYPERTENSIONRICHARD GILLUM; Fiscal Year: 1980..2. Weight maintenance plus dietary sodium restriction to 70 mEq sodium per day...
- PATTERNS OF CARDIOVASCULAR REACTIVITY IN BLACKSNorman Anderson; Fiscal Year: 1991..vascular and neuroendocrine reactivity will be examined as a function of resting blood pressure level, dietary sodium intake, and socioeconomic status...
- Plasticity of Gustatory Primary Afferent CircuitryOlivia May; Fiscal Year: 2004..fields have been identified as regions undergoing considerable plasticity in response to restriction of dietary sodium during development...
- VASCULAR EFFECTS OF INHIBITORY BEHAVIORAL ADAPTATIONSDavid Anderson; Fiscal Year: 1980..Dogs will be exposed to (a) stress conditioning in a context of dietary sodium restriction, (b) salt loading without stress conditioning, or (c) stress conditioning plus salt loading over ..
- End organ damage in children with primary hypertensionDeborah Jones; Fiscal Year: 2009..members with hypertension, insulin resistance, low birth weight or intrauterine growth retardation and liberal dietary sodium. Therefore, it seems intuitive that prevention of adult cardiovascular disease should begin during childhood...
- ADOLESCENT BLOOD PRESSURE VARIATION AND VENTRICULARCRAIG EWART; Fiscal Year: 1990..if a tendency to hyperkinetic circulation and higher prevailing BP exacerbated by personality, stress, and dietary sodium lead to increase LVH at follow-up...
- TRANSTELEPHONIC MONITORING OF HYPERTENSION IN AFRICAN AMWILLIAM GENTHE; Fiscal Year: 2000..3) Achievement of appropriate lifestyle changes (weight loss, dietary sodium and fat restriction, increase in exercise, decrease in alcohol intake, and smoking cessation) that will ..
- NEUROBEHAVIORAL BASES OF STRESS-INDUCED HYPERTENSIONJames Lawler; Fiscal Year: 1991..A number of hypotheses relating the interactions between dietary sodium intake, tail shock stress, exercise and genetic history of hypertension will be tested in animals - with ..
- TREATMENT OF MILD HYPERTENSION STUDY (TOMHS)Richard Grimm; Fiscal Year: 1991..group also is advised nonpharmacologic methods to control their blood pressure including weight loss, dietary sodium reduction, alcohol reduction and increased leisure-time physical activity...
- CENTRAL CONTROL OF OXYTOCIN RELEASE DURING GESTATIONSTEVEN BEALER; Fiscal Year: 2008..abstract_text> ..
- Altered Baroreflex Responses by Dietary SodiumSTEVEN BEALER; Fiscal Year: 2003The along objectives of this research project are to understand the mechanisms through which dietary sodium modifies baroreflex sensitivity...
- Beta-2 Receptor Polymorphisms and Vasodilation in HumansJohn Eisenach; Fiscal Year: 2007..My long-term career goal is to become an independent investigator performing physiology and pharmacology studies directed at the genomics of the cardiovascular system in humans. ..
- BMI, Nutrition, Inflammation and Heart Failure OutcomesTerry Lennie; Fiscal Year: 2007..An understanding of the underlying mechanisms may also allow application of these findings to underweight patients resulting in improved outcomes for these patients. ..
- Neurobehavioral Control of Body Fluid Balance in MouseAlan Johnson; Fiscal Year: 2009..heat) challenges. These studies will be especially important for understanding mechanisms underlying pathological conditions such as hypertension and congestive heart failure where excess thirst and sodium intake have been documented. ..
- Angiotensin II Mediates Early Changes in Diabetic KidneyHelmy Siragy; Fiscal Year: 2007..The proposed studies will help understand the mechanisms that are involved in diabetic the development of new therapeutic modalities to prevent or slowdown the development ..
- AT2 Receptor Modulates Renal Angiotensin II LevelsHelmy Siragy; Fiscal Year: 2005..Data obtained from this proposal will lead to increased understanding of the pathophysiology of hypertension and development of novel therapies for its management. ..
- SEX HORMONES AND BODY FLUID REGULATIONNINA STACHENFELD; Fiscal Year: 2003....